Dr Amna Ghith

• Appointments

  Date	Position	Institution name
  2023 - ongoing	Postdoctoral Researcher	University of Adelaide
  2019 - 2023	HDR / PhD Student	University of Adelaide
  2014 - 2017	MSc Student	Ain Shams University

• Language Competencies

  Language	Competency
  Arabic	Can read, write, speak and understand spoken
  English	Can read, write, speak, understand spoken and peer review
  French	Can read
  Turkish	Can read, write, speak, understand spoken and peer review

• Education

  Date	Institution name	Country	Title
  2019 - 2023	University of Adelaide	Australia	PhD in Chemical Sciences-Chemistry
  2017	Ain Shams University	Egypt	MSc.in Pharmaceutical Sciences-Pharmacy
  2006 - 2011	Ain Shams University	Egypt	BSc Pharmaceutical Sciences Pharmacy

• Postgraduate Training

  Date	Title	Institution	Country
  2021 - 2021	APR Intern	Australian Postgraduate Internship	Australia

• Research Interests

  Biochemistry & Molecular Biology Cancer Cell Biology Crystallography Structural biology (incl. macromolecular modelling)

• Journals

  Year	Citation
  2024	Churchman, L. R., Beckett, J. R., Tan, L., Woods, K., Doherty, D. Z., Ghith, A., . . . De Voss, J. J. (2024). Synthesis of steroidal inhibitors for Mycobacterium tuberculosis. Journal of Steroid Biochemistry and Molecular Biology, 239, 106479-1-106479-16. DOI
  2024	Maleki, R., Ghith, A., Heydarlou, H., Grzeskowiak, L. E., & Ingman, W. V. (2024). The Role of Breastmilk in Macrophage-Tumour Cell Interactions in Postpartum Breast Cancer. Frontiers in Bioscience-Landmark, 29(9), 328-1-328-12. DOI
  2023	Ghith, A., Bruning, J. B., & Bell, S. G. (2023). The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum.. Archives of biochemistry and biophysics, 737, 109554. DOI Scopus2 WoS1
  2023	Mohamed, H., Ghith, A., & Bell, S. G. (2023). The binding of nitrogen-donor ligands to the ferric and ferrous forms of cytochrome P450 enzymes. Journal of Inorganic Biochemistry, 242, 112168. DOI Scopus5 Europe PMC1
  2023	Ghith, A., Bruning, J. B., & Bell, S. G. (2023). The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum.. J Steroid Biochem Mol Biol, 231, 106317-1-106317-12. DOI Scopus1 Europe PMC1
  2023	Doherty, D. Z., Ghith, A., Ho, A., De Voss, J. J., & Bell, S. G. (2023). The bacterial cytochrome P450 (CYP) CYP125 enzymes can competitively oxidise sitosterol in the presence of cholesterol. Chemical Communications, 59(61), 9392-9395. DOI Scopus2
  2023	Ghith, A., & Bell, S. G. (2023). The oxidation of steroid derivatives by the CYP125A6 and CYP125A7 enzymes from Mycobacterium marinum. The Journal of Steroid Biochemistry and Molecular Biology, 235, 106406-1-106406-14. DOI Scopus1
  2022	Ghith, A., Doherty, D. Z., Bruning, J. B., Russell, R. A., De Voss, J. J., & Bell, S. G. (2022). The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum. ACS Infectious Diseases, 8(8), 1606-1617. DOI Scopus7 WoS3 Europe PMC1
  2020	Child, S. A., Ghith, A., Bruning, J. B., & Bell, S. G. (2020). A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis. Journal of Inorganic Biochemistry, 209, 1-12. DOI Scopus13 WoS8 Europe PMC2
  2019	Ghith, A., Youssef, K. M., Ismail, N. S. M., & Abouzid, K. A. M. (2019). Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agents. Bioorganic Chemistry, 83, 111-128. DOI Scopus45 WoS33 Europe PMC12
  2017	Ghith, A., Ismail, N. S. M., Youssef, K., & Abouzid, K. A. M. (2017). Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities. Archiv der Pharmazie, 350(11), 24 pages. DOI Scopus22 WoS14 Europe PMC6

Teaching Chemistry Foundations and Chemitsry for undergrdauates.

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2024	Co-Supervisor	The role of human breast milk in prevention of postpartum breast cancer	Doctor of Philosophy	Doctorate	Full Time	Mr Reza Maleki

• Position: Postdoctoral Researcher
• Email: amna.ghith@adelaide.edu.au
• Fax: 83134380
• Campus: Queen Elizabeth Hospital
• Building: Institute Building
• Org Unit: Surgical Specialities