Sam Henderson
School of Agriculture, Food and Wine
Faculty of Sciences, Engineering and Technology
Sam is a researcher with expertise in plant science, cell membrane biology, and ion channels. His first postdoctoral position was undertaken at the ARC Centre of Excellence in Plant Energy Biology, investigating salinity tolerance in crop plants. He carried out further postdoctoral work at CSIRO, investigating the molecular basis of apomixis in plants. In 2019, he joined Andrea Yool’s team in the Faculty of Health and Medical Sciences, to study the fundamental roles of human aquaporins.
Aquaporins (AQPs) are channels that conduct water and small solutes across cell membranes. Our laboratory aims to understand the physiological role of water and ion conductivity of human AQPs in health and disease.
We use a range of techniques including:
• Recombinant protein production and purification
• Patch-clamp electrophysiology
• Two-electrode voltage clamp (TEVC) electrophysiology
• Cell swelling assays
• Cell culture
• Microbiology
• Advanced microscopy
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Appointments
Date Position Institution name 2019 - ongoing Postdoctoral Research Fellow University of Adelaide 2018 - 2019 Postdoctoral Scientist Commonwealth Scientific and Industrial Research Organisation 2014 - 2017 Postdoctoral Research Associate University of Adelaide 2007 - 2010 Research Officer University of Adelaide 2006 - 2007 Technical Officer Australian Centre for Plant Functional Genomics, University of Adelaide -
Education
Date Institution name Country Title 2014 University of Adelaide Australia PhD 2005 Flinders University Australia Bachelor of Biotechnology (Hons) -
Research Interests
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Journals
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Book Chapters
Year Citation 2015 Henderson, S., & Gilliham, M. (2015). The "Gatekeeper" Concept: Cell-Type Specific Molecular Mechanisms of Plant Adaptation to Abiotic Stress. In R. Laitinen (Ed.), Molecular Mechanisms in Plant Adaptation (pp. 83-116). New Jersey: Wiley.
DOI Scopus20 -
Conference Items
Year Citation 2016 Byrt, C. S., Zhao, M., Kourghi, M., Bose, J., Henderson, S. W., Qui, J., . . . Tyerman, S. (2016). Charging up water transport with plant aquaporins permeable to ions. Poster session presented at the meeting of Combio2016. Brisbane, Australia. -
Preprint
Year Citation 2024 Henderson, S., Nourmohammadi, S., & Hrmova, M. (2024). Protein modelling and thermodynamics reveal that plant cation-chloride cotransporters mediate potassium-chloride symport.
DOI
Date | Grant Title | Investigators | Funding Body |
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2020 - 2021 |
Replacing frog oocytes and animal antibodies in aquaporin research: Developing an animal-free analysis platform to assess human Aquaporin-1 channels involved in cancer cell migration. |
Henderson, SW; Yool AJ; Martinac B | The Medical Advances Without Animals (MAWA) Trust |
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Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2019 Co-Supervisor Functional Study of Grapevine (Vitis vinifera L.) Membrane Ion Transporters Related to Salt Tolerance Doctor of Philosophy Doctorate Full Time Miss Yue Wu
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Memberships
Date Role Membership Country 2010 - ongoing - Australian Society for Plant Scientists (ASPS) Australia
Connect With Me
External Profiles