Richard Young

Research Interests

Nutrition and Metabolic Health

Richard Young

NHMRC Externally-Funded Research Associate Professor

School of Medicine

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

A/Prof Richard L Young is a Senior Research Fellow in the Adelaide Medical School at The University of Adelaide, and the South Australian Health & Medical Research Institute (SAHMRI). He is a member of the Centre of Research Excellence in Translating Nutritional Science to Good Health, which links basic and clinician researchers in world-leading research in diabetes.A/Prof Young heads the Intestinal Sensing Group within the Nutrition, Diabetes and Gut Health Program of SAHMRI Lifelong Health. He investigates the intestinal taste system, which detects dietary sugars and low-calorie sweeteners and, in turn, controls how glucose is absorbed and disposed in the body. He has shown how this system is regulated in health, and its dysregulation in type 2 diabetes, critical illness and obesity. This NHMRC supported research is providing new knowledge of gut physiology and microbiology, with the potential to prevent, and better manage, type 2 diabetes and obesity.

We offer higher degree research projects that span interventional clinical research through to basic research with genetic and disease models. These projects aim to save lives in critical illnesses and can be tailored to the individual student. One-year Honours projects are also available in these areas. Students will be based in the west-end health precinct in SAHMRI, with clinical studies undertaken in the Adelaide University AHMS building (Clinical Research Facility, CRF).

  • Sepsis killsSaving lives in critical illness by preserving cortisol targeting Blood levels of the carrier protein for cortisol fall in many patients with sepsis in a manner that predicts their death. Supplementing this protein in these patients may preserve its unique capacity to deliver the full benefits of cortisol's anti-inflammatory actions to injured tissues. Using our mouse model, which responds to sepsis in the same manner as patients, we aim to provide fundamental knowledge on the value of novel therapies to save lives. This is an exciting space and has the promise to deliver the first new therapy for sepsis management in decades. This project will involve clinical research in Adelaide University CRF and laboratory experiments in SAHMRI. Project start: Semester 1 and 2.

Date Position Institution name
2016 - ongoing Associate Professor The University of Adelaide

Date Institution name Country Title
University of Melbourne, Melbourne Australia PhD
University of Adelaide, Adelaide Australia BSc Honours
University of Adelaide, Adelaide Australia BSc

Year Citation
2026 Ramsay, S. D., Kilgariff, D. E., Young, B. J., Darveniza, L. C., O'Hare Doig, R. L., Hollis, C. A., . . . Young, R. L. (2026). Harnessing native corticosteroid-binding globulin to treat life-threatening septic shock. Endocrinology, 167(2), bqag002-1-bqag002-18.
DOI Europe PMC1
2026 Rose, B. D., Kreuch, D., Wu, T., Horowitz, M., Rayner, C. K., Page, A. J., . . . Young, R. L. (2026). Glycemic Impact of Non-Nutritive Sweeteners in Health and Type 2 Diabetes. NUTRITION REVIEWS, 20 pages.
DOI WoS1
2026 Su Khin, K. L., Youssefi, S., Yang, Q., Page, A. J., Nateri, A. S., Eldeghaidy, S., . . . Idris, I. (2026). Emerging Role of Taste Receptors, Entero-Endocrine Cells in Type 2 Diabetes and Metabolic Disorders. Nutrients, 18(5), 23 pages.
DOI
2026 Sun, Y., Xie, C., Bound, M., Jones, K. L., Horowitz, M., Macdonald, I. A., . . . Wu, T. (2026). Disparities in GLP-1 and GIP responses to small intestinal glucose infusion in individuals with well- and poorly-controlled type 2 diabetes.. Diabetes research and clinical practice, 236, 113235.
DOI
2025 Long, T., Milbourn, C. C., Smith, A., Khin, K. L. S., Page, A. J., Idris, I., . . . Eldeghaidy, S. (2025). Neural Mechanisms and Alterations of Sweet Sensing: Insights from Functional Magnetic Resonance Imaging Studies. Life, 15(7), 1075-1-1075-20.
DOI Scopus1 WoS1 Europe PMC2
2025 Overduin, T. S., Clarke, G. S., Li, H., Young, R. L., Gatford, K. L., & Page, A. J. (2025). Differential changes in anatomical, molecular and functional determinants of intestinal glucose absorption during murine pregnancy.. Physiological Reports, 13(15), e70493-1-e70493-15.
DOI Europe PMC2
2025 Ramsay, S. D., Kilgariff, D. E., Young, B. J., Plummer, M. P., Nenke, M. A., Meyer, E. J., . . . Young, R. L. (2025). Precision Profiling of Disease Progression in Murine Models of Sepsis and Septic Shock. International Journal of Molecular Sciences, 26(20), 9954-1-9954-21.
DOI Scopus3 WoS3
2025 Overduin, T. S., Page, A. J., Young, R. L., & Gatford, K. L. (2025). Adaptations in Gastrointestinal Nutrient Absorption and its Determinants During Pregnancy in Monogastric Mammals: A Scoping Review. Nutrition Reviews, 83(3), e1172-e1196.
DOI Scopus4 WoS4 Europe PMC2
2025 Ramsay, S. D., Nenke, M. A., Meyer, E. J., Torpy, D. J., & Young, R. L. (2025). Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy. Frontiers in Endocrinology, 16, 1508848-1-1508848-16.
DOI Scopus2 WoS3 Europe PMC1
2024 Rose, B. D., Pezos, N., Choo, J. M., Wu, T., Rogers, G. B., Ivey, K. L., . . . Young, R. L. (2024). Host or the Hosted? Effects of Non-Nutritive Sweeteners on Intestinal and Microbial Mechanisms of Glycemic Control. Nutrients, 16(21), 3628-1-3628-15.
DOI
2024 Clarke, G. S., Li, H., Ladyman, S. R., Young, R. L., Gatford, K. L., & Page, A. J. (2024). Effect of pregnancy on the expression of nutrient-sensors and satiety hormones in mice.. Peptides, 172, 171114.
DOI Scopus3 WoS3 Europe PMC3
2023 Overduin, T. S., Wardill, H. R., Young, R. L., Page, A. J., & Gatford, K. L. (2023). Active glucose transport varies by small intestinal region and oestrous cycle stage in mice. Experimental physiology, 108(6), 865-873.
DOI Scopus5 WoS5 Europe PMC6
2023 Rose, B. D., Rimm, E. B., Zhang, X., Sun, Q., Huang, T., Young, R. L., & Ivey, K. L. (2023). You are what you drink? How associations between profiles of beverage consumption and type 2 diabetes risk are mediated by biomarker networks. Am J Clin Nutr, 118(1), 68-76.
DOI Scopus1 WoS2 Europe PMC1
2022 Overduin, T. S., Page, A. J., Young, R. L., & Gatford, K. L. (2022). Adaptations in gastrointestinal nutrient absorption and its determinants during pregnancy in monogastric mammals: a scoping review protocol. Jbi Evidence Synthesis, 20(2), 640-646.
DOI Scopus2 WoS2 Europe PMC2
2022 Xie, C., Huang, W., Watson, L. E., Soenen, S., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes - impact on gastric emptying. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1643-e1652.
DOI Scopus24 WoS24 Europe PMC25
2022 Wang, X., Chen, C., Xie, C., Huang, W., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Serum bile acid response to oral glucose is attenuated in patients with early type 2 diabetes and correlates with 2h plasma glucose in individuals without diabetes.. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 24(6), 1134-1142.
DOI Scopus12 WoS11 Europe PMC13
2021 Nunez Salces, M., Li, H., Young, R. L., & Page, A. J. (2021). The secretion of total and acyl ghrelin from the mouse gastric mucosa: Role of nutrients and the lipid chemosensors FFAR4 and CD36. Peptides, 146, 170673-1-170673-9.
DOI Scopus3 WoS3 Europe PMC3
2021 Clarke, G. S., Gatford, K. L., Young, R. L., Grattan, D. R., Ladyman, S. R., & Page, A. J. (2021). Maternal adaptations to food intake across pregnancy: Central and peripheral mechanisms.. Obesity (Silver Spring, Md.), 29(11), 1813-1824.
DOI Scopus30 WoS26 Europe PMC25
2021 Xie, C., Huang, W., Wang, X., Trahair, L. G., Pham, H. T., Marathe, C. S., . . . Wu, T. (2021). Gastric emptying in health and type 2 diabetes: an evaluation using a 75g oral glucose drink. Diabetes Research and Clinical Practice, 171(108610), 1-8.
DOI Scopus28 WoS28 Europe PMC23
2021 Sun, E. W., Martin, A. M., de Fontgalland, D., Sposato, L., Rabbitt, P., Hollington, P., . . . Keating, D. J. (2021). Evidence for glucagon secretion and function within the human gut. Endocrinology, 162(4), 4-12.
DOI Scopus11 WoS10 Europe PMC7
2021 Xie, C., Huang, W., Young, R. L., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2021). Role of bile acids in the regulation of food intake, and their dysregulation in metabolic disease. Nutrients, 13(4), 1-16.
DOI Scopus102 WoS99 Europe PMC71
2021 Sun, E. W., Iepsen, E. W., Pezos, N., Lumsden, A. L., Martin, A. M., Schober, G., . . . Keating, D. J. (2021). A gut-intrinsic melanocortin signalling complex augments L cell secretion in humans. Gastroenterology, 161(2), 536-547.
DOI Scopus14 WoS15 Europe PMC11
2020 Li, H., Clarke, G. S., Christie, S., Ladyman, S. R., Kentish, S. J., Young, R. L., . . . Page, A. J. (2020). Pregnancy-related plasticity of gastric vagal afferent signals in mice.. American journal of physiology. Gastrointestinal and liver physiology, 320(2), 10 pages.
DOI Scopus18 WoS18 Europe PMC13
2020 Nunez Salces, M., Li, H., Feinle-Bisset, C., Young, R. L., & Page, A. J. (2020). The regulation of gastric ghrelin secretion.. Acta Physiol (Oxf), 231(3), e13588.
DOI Scopus39 WoS36 Europe PMC31
2020 Nunez-Salces, M., Li, H., Feinle-Bisset, C., Young, R. L., & Page, A. J. (2020). Nutrient-sensing components of the mouse stomach and the gastric ghrelin cell. Neurogastroenterology & Motility, 32(12), 1-13.
DOI Scopus15 WoS12 Europe PMC10
2020 Huang, W., Xie, C., Young, R. L., Zhao, J., Ebendorff-Heidepriem, H., Jones, K. L., . . . Wu, T. (2020). Development of innovative tools for investigation of nutrient-gut interaction. World Journal of Gastroenterology, 26(25), 3562-3576.
DOI Scopus10 WoS10 Europe PMC7
2019 Malbert, C. H., Horowitz, M., & Young, R. L. (2019). Low-calorie sweeteners augment tissue-specific insulin sensitivity in a large animal model of obesity. European Journal of Nuclear Medicine and Molecular Imaging, 46(11), 2380-2391.
DOI Scopus11 WoS12 Europe PMC9
2019 Findeisen, M., Allen, T. L., Henstridge, D. C., Kammoun, H., Brandon, A. E., Baggio, L. L., . . . Febbraio, M. A. (2019). Treatment of type 2 diabetes with the designer cytokine IC7Fc. Nature, 574(7776), 63-68.
DOI Scopus73 WoS70 Europe PMC65
2019 Sun, E. W. L., Martin, A. M., Young, R. L., & Keating, D. J. (2019). The regulation of peripheral metabolism by gut-derived hormones. Frontiers in Endocrinology, 9(JAN), 1-11.
DOI Scopus40 WoS50 Europe PMC43
2019 Lumsden, A. L., Martin, A. M., Sun, E. W., Schober, G., Isaacs, N. J., Pezos, N., . . . Keating, D. J. (2019). Sugar responses of human enterochromaffin cells depend on gut region, sex, and body mass. Nutrients, 11(2), 1-13.
DOI Scopus23 WoS22 Europe PMC23
2019 Zhang, X., Young, R. L., Bound, M., Hu, S., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes. Diabetes Care, 42(4), 520-528.
DOI Scopus52 WoS49 Europe PMC40
2019 Sun, E. W., Martin, A. M., Wattchow, D. A., deFontgalland, D., Rabbitt, P., Hollington, P., . . . Keating, D. J. (2019). Metformin triggers PYY secretion in human gut mucosa. The Journal of clinical endocrinology and metabolism, 104(7), 2668-2674.
DOI Scopus22 WoS19 Europe PMC18
2018 Bahne, E., Sun, E. W., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., . . . Knop, F. K. (2018). Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes. JCI Insight, 3(23), e93936-1-e93936-15.
DOI Scopus143 WoS136 Europe PMC117
2018 Kreuch, D., Keating, D. J., Wu, T., Horowitz, M., Rayner, C. K., & Young, R. L. (2018). Gut mechanisms linking intestinal sweet sensing to glycemic control. Frontiers in Endocrinology, 9, 741-1-741-11.
DOI Scopus37 WoS33 Europe PMC27
2018 Little, T. J., Cvijanovic, N., DiPatrizio, N. V., Argueta, D. A., Rayner, C. K., Feinle-Bisset, C., & Young, R. L. (2018). Plasma endocannabinoid levels in lean, overweight, and obese humans: relationships to intestinal permeability markers, inflammation, and incretin secretion. American Journal of Physiology: Endocrinology and Metabolism, 315(4), E489-E495.
DOI Scopus41 WoS34 Europe PMC33
2018 Young, R., Lumsden, A., Martin, A., Schober, G., Pezos, N., Thazhath, S., . . . Keating, D. (2018). Augmented capacity for peripheral serotonin release in human obesity. International Journal of Obesity, 42(11), 1880-1889.
DOI Scopus81 WoS72 Europe PMC61
2018 Xie, C., Wang, X., Young, R. L., Horowitz, M., Rayner, C. K., & Wu, T. (2018). Role of intestinal bitter sensing in enteroendocrine hormone secretion and metabolic control. Frontiers in Endocrinology, 9, 576-1-576-10.
DOI Scopus68 WoS62 Europe PMC46
2017 Cvijanovic, N., Isaacs, N., Rayner, C., Feinle-Bisset, C., Young, R., & Little, T. (2017). Lipid stimulation of fatty acid sensors in the human duodenum: relationship with gastrointestinal hormones, BMI and diet. International Journal of Obesity, 41(2), 233-239.
DOI Scopus21 WoS21 Europe PMC20
2017 Martin, A., Lumsden, A., Young, R., Jessup, C., Spencer, N., & Keating, D. (2017). The nutrient-sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon. Neurogastroenterology and Motility, 29(6), e13046-1-e13046-8.
DOI Scopus64 WoS56 Europe PMC49
2017 Martin, A., Young, R., Leong, L., Rogers, G., Spencer, N., Jessup, C., & Keating, D. (2017). The diverse metabolic roles of peripheral serotonin. Endocrinology, 158(5), 1049-1063.
DOI Scopus209 WoS197 Europe PMC159
2017 Martin, A., Lumsden, A., Young, R., Jessup, C., Spencer, N., & Keating, D. (2017). Regional differences in nutrient-induced secretion of gut serotonin. Physiological Reports, 5(6), 1-12.
DOI Scopus75 WoS68 Europe PMC64
2017 Sun, E., De Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., . . . Keating, D. (2017). Mechanisms controlling glucose-induced GLP-1 secretion in human small intestine. Diabetes, 66(8), 2144-2149.
DOI Scopus125 WoS120 Europe PMC103
2017 Cvijanovic, N., Isaacs, N., Rayner, C., Feinle-Bisset, C., Young, R., & Little, T. (2017). Duodenal fatty acid sensor and transporter expression following acute fat exposure in healthy lean humans. Clinical Nutrition, 36(2), 1-6.
DOI Scopus16 WoS14 Europe PMC14
2016 Rogers, G. B., Keating, D. J., Young, R. L., Wong, M. L., Licinio, J., & Wesselingh, S. (2016). From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways. Molecular Psychiatry, 21(6), 738-748.
DOI Scopus865 WoS759 Europe PMC695
2016 Lumsden, A., Young, R., Pezos, N., & Keating, D. (2016). Huntingtin-associated protein 1: eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine. BMC Evolutionary Biology, 16(1), 214-1-214-18.
DOI Scopus8 WoS9 Europe PMC6
2016 Richardson, C., Hachach-Haram, N., Billingsley, M., Timoney, N., Grant, W., Gerarchi, P., . . . Kirkpatrick, N. (2016). Facing The World in Vietnam: Feedback From Trainees on the Educational Value of Surgical Missions to Help Patients With Craniofacial Deformities. JOURNAL OF CRANIOFACIAL SURGERY, 27(7), 1715-1718.
DOI WoS2
2015 Zelkas, L., Raghupathi, R., Lumsden, A., Martin, A., Sun, E., Spencer, N., . . . Keating, D. (2015). Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability. Nutrition and Metabolism, 12(1), 55.
DOI Scopus46 WoS40 Europe PMC38
2015 Cvijanovic, N., Feinle-Bisset, C., Young, R., & Little, T. (2015). Oral and intestinal sweet and fat tasting: impact of receptor polymorphisms and dietary modulation for metabolic disease. Nutition Reviews, 73(5), 318-334.
DOI Scopus18 WoS17 Europe PMC14
2015 Young, R. L., Lumsden, A. L., & Keating, D. J. (2015). Gut serotonin is a regulator of obesity and metabolism. Gastroenterology, 149(1), 253-255.
DOI Scopus40 Europe PMC35
2015 Reddi, B., Beltrame, J., Young, R., & Wilson, D. (2015). Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model. Intensive Care Medicine Experimental, 3(1), 36-1-36-15.
DOI Scopus8 Europe PMC5
2015 Symonds, E., Peiris, M., Page, A., Chia, B., Dogra, H., Masding, A., . . . Blackshaw, L. (2015). Mechanisms of activation of mouse and human enteroendocrine cells by nutrients. Gut, 64(4), 618-626.
DOI Scopus104 WoS97 Europe PMC81
2014 Little, T., Isaacs, N., Young, R., Ott, R., Nguyen, N., Rayner, C., . . . Feinle-Bisset, C. (2014). Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index. American Journal of Physiology. Gastrointestinal and Liver Physiology, 307(10), G958-G967.
DOI Scopus49 WoS46 Europe PMC44
2014 Nguyen, N., Debreceni, T., Bambrick, J., Chia, B., Deane, A., Wittert, G., . . . Young, R. (2014). Upregulation of intestinal glucose transporters after Roux-en-Y gastric bypass to prevent carbohydrate malabsorption. Obesity, 22(10), 2164-2171.
DOI Scopus57 WoS54 Europe PMC52
2014 Thazhath, S., Wu, T., Young, R., Horowitz, M., & Rayner, C. (2014). Glucose absorption in small intestinal diseases. Expert Review of Gastroenterology and Hepatology, 8(3), 301-312.
DOI Scopus20 WoS18 Europe PMC16
2014 Deane, A., Rayner, C., Keeshan, A., Cvijanovic, N., Marino, Z., Nguyen, Q., . . . Young, R. (2014). The effects of critical illness on intestinal glucose sensing, transporters and absorption. Critical Care Medicine, 42(1), 57-65.
DOI Scopus71 WoS68 Europe PMC60
2014 Nguyen, N., Debreceni, T., Bambrick, J., Chia, B., Wishart, J., Deane, A., . . . Young, R. (2014). Accelerated intestinal glucose absorption in morbidly obese humans: relationship to glucose transporters, incretin hormones, and glycaemia. Journal of Clinical Endocrinology and Metabolism, 100(3), 968-976.
DOI Scopus105 WoS98 Europe PMC84
2013 Wu, T., Bound, M., Standfield, S., Bellon, M., Young, R., Jones, K., . . . Rayner, C. (2013). Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans. Diabetes Care, 36(12), e202-e203.
DOI Scopus52 WoS53 Europe PMC48
2013 Wu, T., Rayner, C., Young, R., & Horowitz, M. (2013). Gut motility and enteroendocrine secretion. Current Opinion in Pharmacology, 13(6), 928-934.
DOI Scopus95 WoS83 Europe PMC66
2013 Young, R., Chia, C., Isaacs, N., Ma, J., Khoo, J., Wu, T., . . . Rayner, C. (2013). Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes. Diabetes, 62(10), 3532-3541.
DOI Scopus97 WoS89 Europe PMC72
2013 Harrington, A., Brierley, S., Isaacs, N., Young, R., & Blackshaw, L. (2013). Identifying spinal sensory pathways activated by noxious esophageal acid. Neurogastroenterology and Motility, 25(10), 660-668.
DOI Scopus20 WoS16 Europe PMC15
2013 Li, H., Kentish, S., Kritas, S., Young, R., Isaacs, N., O'Donnell, T., . . . Page, A. (2013). Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W. Acta Physiologica (Print Edition), 209(2), 179-191.
DOI Scopus20 WoS21 Europe PMC20
2013 Kentish, S., O'Donnell, T., Isaacs, N., Young, R., Li, H., Harrington, A., . . . Page, A. (2013). Gastric vagal afferent modulation by leptin is influenced by food intake status. Journal of Physiology-London, 591(7), 1921-1934.
DOI Scopus79 WoS73 Europe PMC64
2012 Page, A., Symonds, E., Peiris, M., Blackshaw, L., & Young, R. (2012). Peripheral neural targets in obesity. British Journal of Pharmacology, 166(5), 1537-1558.
DOI Scopus38 WoS37 Europe PMC29
2012 Kentish, S., Li, H., Philp, L., O'Donnell, T., Isaacs, N., Young, R., . . . Page, A. (2012). Diet-induced adaptation of vagal afferent function. Journal of Physiology-London, 590(1), 209-221.
DOI Scopus120 WoS116 Europe PMC106
2012 Wu, T., Zhao, R., Bound, M., Checklin, H., Bellon, M., Little, T., . . . Rayner, C. (2012). Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. American Journal of Clinical Nutrition, 95(1), 78-83.
DOI Scopus147 WoS140 Europe PMC115
2012 McArdle, A., Young, R., & Kelly, M. H. (2012). Preferences for the White Female Nasal Supratip Break. ANNALS OF PLASTIC SURGERY, 68(4), 366-368.
DOI WoS8
2011 Blackshaw, L., Page, A., & Young, R. (2011). Metabotropic glutamate receptors as novel therapeutic targets on visceral sensory pathways. Frontiers in Neuroscience, 5(40), 1-7.
DOI Scopus30 WoS28 Europe PMC30
2011 Blackshaw, L. A., & Young, R. L. (2011). Detection and signaling of glucose in the intestinal mucosa - vagal pathway. Neurogastroenterology and Motility, 23(7), 591-594.
DOI Scopus8 WoS7 Europe PMC8
2011 Young, R. (2011). Sensing via intestinal sweet taste pathways. Frontiers in Neuroscience, 5(MAR), 23-1-23-13.
DOI Scopus60 WoS54 Europe PMC45
2010 Isaacs, N. J., Young, R. L., Wittert, G., Blackshaw, L. A., & Page, A. J. (2010). Anatomy of gastric vagal afferent innervation in normal and obese mice. NEUROGASTROENTEROLOGY AND MOTILITY, 22, 9.
2010 Ma, J., Chang, J., Checklin, H., Young, R., Jones, K., Horowitz, M., & Rayner, C. (2010). Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects. British Journal of Nutrition, 104(6), 803-806.
DOI Scopus124 WoS111 Europe PMC104
2010 Young, R., Page, A., Isaacs, N., Flach, C., & Blackshaw, L. (2010). Sensory and Motor Innervation of the Crural Diaphragm by the Vagus Nerves. Gastroenterology, 138(3), 1091-1106.
DOI Scopus56 WoS38 Europe PMC31
2010 Ma, J., Bellon, M., Wishart, J., Young, R., Jones, K., Horowitz, M., & Rayner, C. (2010). Effects of cefaclor on gastric emptying and cholecystokinin release in healthy humans. Regulatory Peptides, 159(1-3), 156-159.
DOI Scopus5 WoS4 Europe PMC2
2009 Page, A., O'Donnell, T., Isaacs, N., Young, R., & Blackshaw, L. (2009). Nitric Oxide as an Endogenous Peripheral Modulator of Visceral Sensory Neuronal Function. Journal of Neuroscience, 29(22), 7246-7255.
DOI Scopus41 WoS38 Europe PMC32
2009 Ma, J., Bellon, M., Wishart, J., Young, R., Blackshaw, L., Jones, K., . . . Rayner, C. (2009). Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects. American Journal of Physiology-Gastrointestinal and Liver Physiology, 296(4), G735-G739.
DOI Scopus222 WoS207 Europe PMC179
2009 Young, R., Sutherland, K., Pezos, N., Brierley, S., Horowitz, M., Rayner, C., & Blackshaw, L. (2009). Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes. Gut, 2008(3), 337-346.
DOI Scopus163 WoS160 Europe PMC143
2008 Young, R., Isaacs, N., & Blackshaw, L. (2008). Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways. Neuropharmacology, 54(6), 965-975.
DOI Scopus24 WoS22 Europe PMC19
2008 Young, R., Isaacs, N., & Blackshaw, L. (2008). Chemical coding and central projections of gastric vagal afferent neurons. Neurogastroenterology and Motility, 20(6), 708-718.
DOI Scopus30 WoS24 Europe PMC23
2007 Young, R., Page, A., Isaacs, N., O'Donnell, T., & Blackshaw, L. (2007). Peripheral versus central modulation of gastric vagal pathways by metabotropic glutamate receptor 5. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(2), G501-G511.
DOI Scopus39 WoS33 Europe PMC33
2007 Sutherland, K., Young, R., Isaacs, N., Horowitz, M., & Blackshaw, L. (2007). Phenotypic characterization of taste cells of the mouse small intestine. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(5), G1420-G1428.
DOI Scopus117 WoS113 Europe PMC103
2007 Hughes, P., Brierley, S., Young, R., & Blackshaw, L. (2007). Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia. Journal of Comparative Neurology, 500(5), 863-875.
DOI Scopus89 WoS79 Europe PMC76
2005 Page, A., Slattery, J., O'Donnell, T., Isaacs, N., Young, R., & Blackshaw, L. (2005). Modulation of gastro-oesophageal vagal afferents by galanin in mouse and ferret. Journal of Physiology-London, 563(3), 809-819.
DOI Scopus33 WoS25 Europe PMC27
2005 Page, A., Young, R., Martin, C., Umaerus, M., O'Donnell, T., Isaacs, N., . . . Blackshaw, L. (2005). Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons. Gastroenterology, 128(2), 402-410.
DOI Scopus87 WoS73 Europe PMC70
2001 Partosoedarso, E., Young, R., & Blackshaw, L. (2001). GABAB receptors on vagal afferent pathways: peripheral and central inhibition. American Journal of Physiology-Gastrointestinal and Liver Physiology, 280(4), G658-G668.
DOI Scopus71 WoS62 Europe PMC51
2001 Smid, S., Young, R., Isaacs, N., & Blackshaw, L. (2001). GABABR expressed on vagal afferent neurones inhibit gastric mechanosensitivity in ferret proximal stomach. American Journal of Physiology - Gastrointestinal and Liver Physiology, 281(6), G1494-G1501.
DOI Scopus67 WoS50 Europe PMC47
2001 Sakaguchi, G., Young, R., Komeda, M., Yamanaka, K., Buxton, B., & Louis, W. (2001). Left ventricular aneurysm repair in rats: Structural, functional, and molecular consequences. Journal of Thoracic and Cardiovascular Surgery, 121(4), 750-761.
DOI Scopus13 WoS11 Europe PMC9
1998 Young, R. L., Gundlach, A. L., & Louis, W. J. (1998). Altered cardiac hormone and contractile protein messenger RNA levels following left ventricular myocardial infarction in the rat: An in situ hybridization histochemical study. Cardiovascular Research, 37(1), 187-201.
DOI Scopus10 WoS10 Europe PMC7
1993 Young, R. L., Jonsson, J. R., Mano, M. T., Frewin, D. B., & Head, R. J. (1993). Influence of α1and α2-adrenoceptor antagonist therapy on the development of hypertension in spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology, 21(5), 780-790.
DOI Scopus3 WoS5 Europe PMC3

Year Citation
2019 Martin, A. M., Young, R. L., Leong, L., Rogers, G. B., Spencer, N. J., Jessup, C. F., & Keating, D. J. (2019). Cellular regulation of peripheral serotonin. In P. M. Pilowsky (Ed.), Serotonin: The Mediator that Spans Evolution (pp. 137-153). London, United Kingdom: Academic Press.
DOI Scopus6 WoS5

Year Citation
2024 Huang, W., Xie, C., Xiang, C., Li, T., Young, R. L., Zhao, J., . . . Wu, T. (2024). A gut-on-a-chip platform to monitor GLP-1 secretion dynamics from primary intestinal tissue. In DIABETOLOGIA Vol. 67 (pp. S395). SPAIN, Madrid: SPRINGER.
2024 Sun, Y., Xie, C., Bound, M., Jones, K. L., Horowitz, M., Young, R., . . . Wu, T. (2024). Disparities in GLP-1 and GIP responses to small intestinal glucose infusion between people with well- and poorly-controlled type 2 diabetes. In DIABETOLOGIA Vol. 67 (pp. S92). SPAIN, Madrid: SPRINGER.
DOI
2023 Clark, V. E., & Young, R. (2023). EZH2 Inhibition Decreases SMARCB1 and NF2 Mutant Meningioma Cell Viability. In NEUROSURGERY Vol. 69 (pp. 177). DC, Washington: LIPPINCOTT WILLIAMS & WILKINS.
2021 Clark, V., Charalampos, L., & Young, R. (2021). RNA Polymerase II Meningioma Mutations Dysregulate Transcriptional Pause-Release and Exhibit Susceptibility to CDK9 Inhibition. In JOURNAL OF NEUROSURGERY Vol. 135 (pp. 44). ELECTR NETWORK: AMER ASSOC NEUROLOGICAL SURGEONS.
2019 Young, R., Williams, P., Lo, T., Athanasiou, A., Mehta, S., Dexter, S., . . . Hayden, J. (2019). Pathological and early surgical outcomes of oesophagectomy after neoadjuvant FLOT chemotherapy in a single centre UK tertiary referral centre. In BRITISH JOURNAL OF SURGERY Vol. 106 (pp. 68). ENGLAND, Liverpool: WILEY.
2018 Nam, Q. N., Naidu, J., Debricini, T., Burgess, J., Safaeian, R., Young, R., & Horowitz, M. (2018). Is dysregulation of intestinal glucose transporters in the morbidly obese responsible for the development of diabetes mellitus?. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 33 (pp. 218-219). WILEY.
2017 Youngblood, M. W., Clark, V., Harmanci, A. S., Bai, H., Mora, D. D., Montejo, J., . . . Gunel, M. (2017). Clinical and Molecular Features of Genomic Subgroups in Meningioma. In JOURNAL OF NEUROSURGERY Vol. 126 (pp. A1424). CA, Los Angeles: AMER ASSOC NEUROLOGICAL SURGEONS.
WoS3
2014 Nguyen, N. Q., Debreceni, T. L., Bambrick, J. E., Chia, B., Wishart, J. M., Wittert, G. A., . . . Young, R. L. (2014). Impact of a 2-Week Very Low Calorie Diet (VLCD) on Glucose Sensing, Absorption, Transporters, Incretin Hormones and Glycemia in Morbidly Obese Humans. In GASTROENTEROLOGY Vol. 146 (pp. S899). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC.
2014 Nguyen, N. Q., Debreceni, T. L., Bambrick, J. E., Chia, B., Wishart, J. M., Deane, A. M., . . . Young, R. L. (2014). Accelerated Glucose Absorption in Proximal Intestine and Its Relationship to Glucose Transporters, Incretin Hormones and Glycaemia in Morbidly Obese Humans: the "X-Factor" of the Foregut Theory?. In GASTROENTEROLOGY Vol. 146 (pp. S108). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
2013 Nguyen, N. Q., Debreceni, T. L., Chia, B., Burgstad, C. M., Neo, M., Deane, A. M., . . . Young, R. L. (2013). Intestinal Sweet Taste Receptor and Transporter Expression, Post-Prandial Glycemia and Glucose Absorption in Morbidly Obese Subjects. In GASTROENTEROLOGY Vol. 144 (pp. S836). Orlando, FL: W B SAUNDERS CO-ELSEVIER INC.
2013 Harrington, A. M., Castro, J., Young, R. L., Kurtz, C. B., Silos-Santiago, A., Nguyen, N. Q., . . . Brierley, S. M. (2013). Alterations in the Guanylate Cyclase-C/cGMP Pathway in Patients With Irritable Bowel Syndrome With Constipation. In GASTROENTEROLOGY Vol. 144 (pp. S59-S60). Orlando, FL: W B SAUNDERS CO-ELSEVIER INC.
2013 Nguyen, N. Q., Debreceni, T. L., Chia, B., Burgstad, C. M., Neo, M., Wittert, G. A., . . . Young, R. L. (2013). Alterations in the Expression of Intestinal Sweet Taste Receptor and Glucose Transporters After Roux-en-Y Gastric Bypass: An Adaptive Response to Prevent Carbohydrate Malabsorption. In GASTROENTEROLOGY Vol. 144 (pp. S64). FL, Orlando: W B SAUNDERS CO-ELSEVIER INC.
2011 Young, R. L., Chia, B., Ma, J., Wu, T., Khoo, J., Horowitz, M., . . . Rayner, C. (2011). Disordered Control of Intestinal Sweet Taste Receptor Expression in Type 2 Diabetes. In GASTROENTEROLOGY Vol. 140 (pp. S99-S100). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC.
2011 Young, R. L., Deane, A. M., Chia, B., Horowitz, M., Blackshaw, L. A., & Rayner, C. (2011). Dysregulation of Intestinal Glucose Transporter and Sweet Taste Receptor Expression in Critical Illness. In GASTROENTEROLOGY Vol. 140 (pp. S194). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
2011 Little, T., Young, R., Blackshaw, L., Rayner, C., & Feinle-Bisset, C. (2011). Expression of the fatty acid sensors, CD36, GPR119 and GPR120, in the duodenum of humans. Relationships with obesity. In 19th Annual Meeting of the Society for the Study of Ingestive Behavior Vol. 575 (pp. S26). Netherlands: Elsevier BV.
DOI
2011 Wu, T., Zhao, B., Bound, M., Checklin, H. L., Bellon, M., Little, T. J., . . . Rayner, C. K. (2011). Effects of different sweet preloads on incretin hormone responses, gastric emptying and postprandial glycaemia in healthy humans. In DIABETOLOGIA Vol. 54 (pp. S330). Lisbon, PORTUGAL: SPRINGER.
2010 Harrington, A., Young, R., Brierley, S., & Blackshaw, L. (2010). TRPV1 mediates acid activation of esophageal sensory pathways. In Proceedings of 2010 Joint International Neurogastroenterology and Motility Meeting, NGM 2010 Vol. 22 (pp. 55). UK: Wiley-Blackwell Publishing Ltd.
2008 Sutherland, K., Brierley, S. M., Rayner, C., Horowitz, M., Blackshaw, L. A., & Young, R. L. (2008). Altered duodenal sweet taste receptor expression in diabetic hyperglycemia. In GASTROENTEROLOGY Vol. 134 (pp. A44). W B SAUNDERS CO-ELSEVIER INC.
2007 Sutherland, K., Brierley, S. M., Horowitz, M., Rayner, C., Blackshaw, L. A., & Young, R. L. (2007). Sweet taste transduction molecules are expressed in the upper gastrointestinal tract in humans. In GASTROENTEROLOGY Vol. 132 (pp. A587). Washington, DC: W B SAUNDERS CO-ELSEVIER INC.
WoS3
2007 Pezos, N., Sutherland, K., Brierley, S. M., Horowitz, M., Blackshaw, L. A., & Young, R. L. (2007). Vagal afferents do not directly detect intestinal glucose via a sweet-taste mechanism. In GASTROENTEROLOGY Vol. 132 (pp. A587). Washington, DC: W B SAUNDERS CO-ELSEVIER INC.
2006 Sutherland, K., Cooper, N. J., Horowitz, M., Margolskee, R. F., Blackshaw, L. A., & Young, R. L. (2006). Taste receptor G-protein α-gustducin does not colocalise with enteroendocrine cell markers in the mouse intestine. In GASTROENTEROLOGY Vol. 130 (pp. A605). Los Angeles, CA: W B SAUNDERS CO-ELSEVIER INC.
2005 Gountounas, N., Cooper, N. J., Horowitz, M., Margolskee, R. F., Blackshaw, L. A., & Young, R. L. (2005). Does the gut 'taste' sweet? Identifying glucosensor molecules in the small intestine. In GASTROENTEROLOGY Vol. 128 (pp. A555). Chicago, IL: W B SAUNDERS CO.
2002 Young, R. L., Cooper, N. J., & Blackshaw, L. A. (2002). Neurochemical coding of gastric vago-vagal pathways in the ferret. In JOURNAL OF PHYSIOLOGY-LONDON Vol. 543 (pp. 5P). UNIV LIVERPOOL, LIVERPOOL, ENGLAND: CAMBRIDGE UNIV PRESS.

Year Citation
2020 Li, H., Christie, S., Clarke, G., Watson, O., Young, R., Gatford, K., & Page, A. (2020). Gastric vagal afferent satiety signals are attenuated during pregnancy. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2020 Kreuch, D., Ivey, K., Mobegi, F. M., Leong, L., Isaacs, N. J., Pezos, N., . . . Young, R. L. (2020). Mechanisms linking low-calorie sweeteners to impaired glycaemic control. Poster session presented at the meeting of Abstracts of the 4th Meeting of the Federation of Neurogastroenterology and Motility (FNM 2020), as published in Neurogastroenterology and Motility. Adelaide Convention Centre, Adelaide, Australia: Wiley.
DOI
2020 Nunez-Salces, M., Li, H., Young, R. L., Feinle-Bisset, C., & Page, A. J. (2020). Nutrient-sensing mechanisms of the gastric ghrelin cell. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2020 Xie, C., Wang, X., Bound, M. J., Young, R. L., Jones, K. L., Horowitz, M., . . . Wu, T. (2020). Bitter taste signalling modulates bile acid-induced PYY, but not GLP-1 secretion in healthy humans. Poster session presented at the meeting of Abstracts of the 56th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Virtual Online: Springer-Verlag.
DOI
2018 Xie, C., Wang, X., Bound, M. J., Grivell, J., Young, R. L., Jones, K. L., . . . Wu, T. (2018). Effects of the bitter taste receptor agonist, denatonium benzoate, on postprandial glycaemia, gastric emptying and energy intake in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI Europe PMC9
2018 Young, R. L., Kreuch, D., Mobegi, F. M., Leong, L., Schober, G., Isaacs, N. J., . . . Rogers, G. B. (2018). Low-calorie sweeteners disrupt the gut microbiome in healthy subjects in association with impaired glycaemic control. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI
2017 Young, R., Isaacs, N., Schober, G., Wu, T., Cvijanovic, N., Pezos, N., . . . Horowitz, M. (2017). Impact of artificial sweeteners on glycaemic control in healthy humans. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS4
2015 Nguyen, N. Q., Burgess, J. E., Debrecini, T. L., Wishart, J., Rayner, C. K., Horowitz, M., & Young, R. L. (2015). Impact of a 2-week very low calorie diet (vlcd) on fatty acid sensing and transport, incretin hormones and lipid profile in morbidly obese humans. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL.
2014 Harrington, A. M., Castro, J., Young, R. L., Kurtz, C., Silos-Santiago, A., Nguyen, N., . . . Brierley, S. M. (2014). Distinct alterations in the guanylate cyclase-C/cGMP pathway are evident across different subtypes of irritable bowel syndrome patients. Poster session presented at the meeting of Neurogastroenterology and Motility. Guangzhou, China: John Wiley and Sons.
DOI
2014 Harrington, A. M., Castro, J., Young, R. L., Kurtz, C. B., Silos-Santiago, I., Nguyen, N. Q., . . . Brierley, S. M. (2014). Distinct Alterations in the Guanylate Cyclase-C (GC-C)/Cyclic GMP (cGMP) Pathway Are Evident Across Different Subtypes of Irritable Bowel Syndrome (IBS) Patients. Poster session presented at the meeting of GASTROENTEROLOGY. Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
WoS3
2013 Harrington, A. M., Castro, J., Young, R. L., Kurtz, C., Silos-Santiago, A., Nguyen, N., . . . Brierley, S. M. (2013). The guanylatecyclase-c/CGMP pathway is altered in patients with irritable bowel syndrome with constipation. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY-BLACKWELL.
DOI
2013 Namq, N., Debreceni, T., Chia, B., Burgstad, C., Neo, M., Deane, A., . . . Young, R. (2013). Abnormal intestinal glucose transport & absorption in obesity: implication in weight gain & diabetes. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Shanghai, China: Wiley-Blackwell.
2013 Namq, N., Debreceni, T., Chia, B., Burgstad, C., Neo, M., Wittert, G., . . . Young, R. (2013). Upregulation of intestinal glucose transporters after RYGB prevents carbohydrate. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
2013 Nguyen, N. Q., Debreceni, T. L., Chia, B., Burgstad, C. M., Neo, M., Wittert, G. A., . . . Young, R. L. (2013). Alterations in the expression of intestinal sweet taste receptor and glucose transporters after Roux-en-Y gastric bypass: an adaptive response to prevent carbohydrate malabsorption. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
2013 Nguyen, N. Q., Debreceni, T. L., Chia, B., Burgstad, C. M., Neo, M., Deane, A. M., . . . Young, R. L. (2013). Dysregulation of intestinal glucose absorption and glucose transporters in morbidly obesity: potential molecular mechanisms of weight gain and diabetes in obesity. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Melbourne, Vic.: Wiley.
DOI
2010 Isaacs, N., Flach, C., Young, R., Wittert, G., Blackshaw, L., & Page, A. (2010). Anatomy of gastric vagal afferent-leptin interactions in normal and obese mice. Poster session presented at the meeting of Abstracts of the 111th Annual Meeting of the American-Gastroenterological-Association/Digestive Disease Week, as published in Gastroenterology. USA: W.B. Saunders Co..
DOI
2010 Young, R., Sutherland, K., Pezos, N., Brierley, S., Ma, J., Rayner, C., . . . Blackshaw, L. (2010). Control of intestinal sweet taste receptor expression is impaired in type 2 diabetes. Poster session presented at the meeting of Proceedings of 2010 Joint International Neurogastroenterology and Motility Meeting (NGM), as published in Neurogastroenterology & Motility. Boston, MA, USA: Wiley-Blackwell Publishing.
DOI WoS2

Year Citation
- Ramsay, S., Kilgariff, D., Young, B. J., DARVENIZA, L. C., Doig, R. O., Hollis, C. A., . . . Young, R. (n.d.). Supplementary methods and data for Harnessing a native corticosteroid-binding globulin to treat life -threatening septic shock.
DOI

Year Citation
- Li, H., Clarke, G., Ramsay, S., Kentish, S., Ladyman, S., Young, R., . . . Page, A. (n.d.). Supplementary Figure 2: Pregnancy-related plasticity of gastric vagal afferent signals in mice..
DOI

Year Citation
2025 Long, T., Milbourn, C. C., Smith, A., Khin, K. L. S., Page, A. J., Idris, I., . . . Eldeghaidy, S. (2025). Neural Mechanisms and Alterations of Sweet Sensing: Insights from Functional Magnetic Resonance Imaging Studies.
DOI

NHMRC (last 5 years)

  • 2023-26 Ideas (APP2019948) ‘Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock’. Young RL, Torpy DJ, Nenke MA. AI: Meyer EJ, Plummer MP, Ahamed M.
  • 2023-26 Ideas (APP2020454) ‘Stratifying low-calorie sweeteners for diabetes risk’. Rayner CK, Rogers GB. AI: Young RL, Ivey KL, Snel MF, Miller CL, Wu T, Lange K.
  • 2021-23 Ideas (APP2001271) ‘Characterisation of erusiolin - a new peptide hormone’ Larance M, Hocking S. AI: Young RL, Solon-Biet SM, Neely GG, Samocha-Bonet D, Viardot A, Payne RJ.
  • 2020-23 Ideas (APP1181145) Young RL, Ivey KL. AI: Miller CL, Rayner CK, Keating DJ, Lynn DJ, Rogers, GB, Snel MF, Horowitz M. 'Friend or Foe? Low-calorie sweeteners and glycaemic control in type 2 diabetes'

MRFF (last 5 years)

  • 2024-26 Targeted Translation Research Accelerator, Cardiovascular Disease & Diabetes  Mechanisms (MRFCDDM000009) ‘Sweet tasting kidneys: A novel pathway in glucose homeostasis'. Wu T, Young RL, Rayner CK, Thomas MC, Miller CL, Xie C, Huang W (with Diabetes SA, Pasalidis A).

Diabetes Australia (last 5 years)

  • 2026-7 Project "A novel renal pathway for non-nutritive sweetener risk in prediabetes.  Wu T, Rayner CK, Young RL, Luscombe-Marsh N, Thomas MC.
  • 2024 Project "Regulation of glucose homeostasis by renal ‘sweet taste’ sensing in people with type 2 diabetes. Wu T, Rayner CK, Young RL, Thomas MC, Xie C, Huang W.
  • 2023 Project 'Targeting intestinal bile acid sensing mechanisms to manage type 2 diabetes.' Wu T, Rayner CK, Horowitz M, Young RL, Xie C, Jones KL.
  • 2023 Project 'Impact of renal 'sweet taste' sensing on the risk of dysglycaemia.' Rayner CK, Wu T, Young RL, Thomas MC, Xie C, Huang W.
  • 2022 Project 'Host or the hosted? Mechanisms underlying intestinal control of glycaemia in type 2 diabetes'. Young RL, Rayner CK, Horowitz M, Wu T, Rogers GB, Ivey KL.
  • 2021 Project 'Blocking intestinal sweet taste for glycaemic benefits in type 2 diabetes.' Young RL, Rayner CK, Horowitz M, Wu T, Rogers GB, Ivey KL.
  • 2021 Project 'More or less? Bile acids and glycaemic control in type 2 diabetes. Wu T, Rayner CK, Jones KL, Young RL, Horowitz M. 

Diabetes UK (last 5 years)

  • 2024-7 Project Grant. Identifying the mechanisms of gut–brain axis to sweet sensing in patients with type 2 diabetes using neuroimaging techniques. Eldeghaidy S, Yang Q, Idris I (Nottingham University), Young RL, Page AJ.

Diabetes SA (last 5 years)

  • 2022-23 (Project) 'Blocking intestinal sweet taste for better glycaemic control in type 2 diabetes.' Young RL, Rayner CK, Rogers GB, Horowitz M.

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor Harnessing a native corticosteroid-binding globulin to treat chronic inflammation and life-threatening septic shock Doctor of Philosophy Doctorate Full Time Mr Declan Emmett Kilgariff
2025 Principal Supervisor Investigating biological processes in intestinal sweet-sensing and glycaemic control, using pre-clinical mouse models Master of Clinical Science Master Full Time Ms Wei Theng Eng
2025 Principal Supervisor Harnessing a native corticosteroid-binding globulin to treat chronic inflammation and life-threatening septic shock Doctor of Philosophy Doctorate Full Time Mr Declan Emmett Kilgariff
2025 Principal Supervisor Investigating biological processes in intestinal sweet-sensing and glycaemic control, using pre-clinical mouse models - Master Full Time Ms Wei Theng Eng
2025 Principal Supervisor Investigating biological processes in intestinal sweet-sensing and glycaemic control, using pre-clinical mouse models Master of Philosophy Master Full Time Ms Wei Theng Eng
2023 Principal Supervisor Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock Master of Clinical Science Master Part Time Mr Benjamin James Young
2023 Principal Supervisor Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock Master of Clinical Science Master Part Time Mr Benjamin James Young

Date Role Research Topic Program Degree Type Student Load Student Name
2020 - 2024 Co-Supervisor Adaptations of small intestinal nutrient absorption during pregnancy in mice Doctor of Philosophy Doctorate Full Time Mr Teunis Sebastian Overduin
2020 - 2024 Principal Supervisor Glycaemic consequences of non-nutritive sweeteners in human health and type 2 diabetes Doctor of Philosophy Doctorate Full Time Braden Rose
2019 - 2023 Principal Supervisor Gut mechanisms linking low-calorie sweeteners to impaired glycaemic control Doctor of Philosophy Doctorate Part Time Miss Denise Kreuch
2012 - 2017 Principal Supervisor Gastrointestinal Nutrient Sensing in Obesity and type 2 Diabetes: Role in Appetite Regulation and Glycaemic Control Doctor of Philosophy Doctorate Full Time Ms Nada Cvijanovic
2004 - 2009 Co-Supervisor Nutrient Sensing Mechanisms in the Small Intestine: Localisation of Taste Molecules in Mice and Humans With and Without Diabetes Doctor of Philosophy Doctorate Full Time Ms Kate Sutherland

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2014 - ongoing External Supervisor Isolation, purification and characterisation of human enteroendocrine cells Flinders University of South Australia School of Medicine, PhD Doctorate Full Time Emily Wai-Ling Sun

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