Braden Rose

Braden Rose

Pdoc Res Fellow (A) (with PhD)

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Dr Braden Rose is an early career postdoctoral researcher for the Intestinal Sensing Group within the Nutrition, Diabetes and Gut Health Program of the Lifelong Health Theme at the South Australian Health and Medical Research Institute (SAHMRI) and the Adelaide Medical School NHMRC Centre for Research Excellence in Translating Nutritional Science to Good Health. Braden’s research investigates the role of intestinal sweet sensing in glycaemic control and its potential as a novel therapeutic target for type 2 diabetes, as well as the glycaemic consequences of non-nutritive sweeteners in health and type 2 diabetes.

My research focuses on understanding the role intestinal sweet sensing plays in controlling blood glucose. I currently lead multiple projects spanning pre-clinical research using genetic mouse models, basic laboratory experiments on ex vivo human tissues, and interventional clinical studies with the aim of finding new ways to treat type 2 diabetes. 

 

RESEARCH PROJECTS AVAILABLE (2025 – 2026):

What role does intestinal sweet sensing play in blood glucose control?

This project will utilise our novel genetic mouse models to determine the precise mechanisms that link sweet sensing in the intestinal wall to glucose absorption and gut hormone responses, and how this affects blood glucose control and the progression of type 2 diabetes. This project may also involve functional and multiomic experiments in collected human biopsy and other tissues, as well as experiments investigating effects on the gut microbiome. These mouse and laboratory experiments will be carried out in SAHMRI and can be modified to better suit a one-year honours project.  

Supervisors: Dr Braden Rose, A/Prof Richard Young

Degree: PhD, Honours

Location:  SAHMRI, North Terrace

Skills learned: Laboratory – mouse experimental skills, tissue processing, cryopreservation, basic lab techniques (PCR, ELISA, IHC). General - literature searching, statistical analysis, data interpretation, increased knowledge on blood glucose control and type 2 diabetes.

 

Date Position Institution name
2024 - ongoing Postdoctoral Researcher University of Adelaide

Date Type Title Institution Name Country Amount
2024 Award SAHMRI PhD Student of 2024 South Australian Health and Medical Research Institute Australia $1,000
2024 Award Dean's Commendation for Doctoral Thesis Excellence The University of Adelaide Australia -
2024 Award ADS Travel Grant Australian Diabetes Society Australia $800
2024 Award Pincus-Taft Young Investigator Award (Finalist) Australian Diabetes Society Australia -
2022 Award ADS Travel Grant Australian Diabetes Society Australia -
2020 Scholarship Research Training Program Scholarship The University of Adelaide Australia -
2019 Award University Medal The University of Adelaide Australia -
2019 Award Bachelor Of Health Medical Science (Hons Award) Medical Specialties Hilda Farmer Bequest The University of Adelaide Australia -
2018 Award Faculty of Sciences Outstanding Academic Achievement Award The University of Adelaide Australia -
2017 Award Faculty of Sciences Outstanding Academic Achievement Award The University of Adelaide Australia -
2016 Award Faculty of Sciences Outstanding Academic Achievement Award The University of Adelaide Australia -

Date Institution name Country Title
2020 - 2024 University of Adelaide Australia PhD
2019 University of Adelaide Australia Bachelor of Health and Medical Sciences with First Class Honours
2016 - 2018 University of Adelaide Australia Bachelor of Science (Biomedical Science)

Year Citation
2024 Rose, B. D., Pezos, N., Choo, J. M., Wu, T., Rogers, G. B., Ivey, K. L., . . . Young, R. L. (2024). Host or the Hosted? Effects of Non-Nutritive Sweeteners on Intestinal and Microbial Mechanisms of Glycemic Control. Nutrients, 16(21), 3628-1-3628-15.
DOI
2023 Rose, B. D., Rimm, E. B., Zhang, X., Sun, Q., Huang, T., Young, R. L., & Ivey, K. L. (2023). You are what you drink? How associations between profiles of beverage consumption and type 2 diabetes risk are mediated by biomarker networks. Am J Clin Nutr, 118(1), 68-76.
DOI Scopus1 WoS2 Europe PMC1
2023 Rezaie, P., Bitarafan, V., Rose, B. D., Lange, K., Mohammadpour, Z., Rehfeld, J. F., . . . Feinle-Bisset, C. (2023). Effects of Quinine on the Glycaemic Response to, and Gastric Emptying of, a Mixed-Nutrient Drink in Females and Males. Nutrients, 15(16), 1-18.
DOI Scopus7 WoS6 Europe PMC3
2022 Rezaie, P., Bitarafan, V., Rose, B. D., Lange, K., Rehfeld, J. F., Horowitz, M., & Feinle-Bisset, C. (2022). Quinine effects on gut and pancreatic hormones and antropyloroduodenal pressures in humans-Role of delivery site and sex.. Journal of Clinical Endocrinology and Metabolism, 107(7), e2870-e2881.
DOI Scopus7 WoS6 Europe PMC6
2021 Rose, B. D., Bitarafan, V., Rezaie, P., Fitzgerald, P. C. E., Horowitz, M., & Feinle-Bisset, C. (2021). Comparative effects of intragastric and intraduodenal administration of quinine on the plasma glucose response to a mixed-nutrient drink in healthy men: relations with glucoregulatory hormones and gastric emptying. Journal of Nutrition, 151(6), 1453-1461.
DOI Scopus17 WoS16 Europe PMC14
- Anjom-Shoae, J., Fitzgerald, P. C. E., Rose, B. D., Bitarafan, V., Rehfeld, J. F., Horowitz, M., & Feinle-Bisset, C. (2025). Effects of combined intraduodenal administration of lauric acid and l-tryptophan on postprandial plasma glucose, glucoregulatory hormones and gastric emptying in type 2 diabetes: a double-blind, randomised, crossover study. Diabetologia.
DOI

Year Citation
2020 Rezaie, P., Rose, B., Bitarafan, V., Fitzgerald, P., Horowitz, M., & Feinle-Bisset, C. (2020). Effects of intragastric vs. intraduodenal administration of the bitter compound, quinine, on gut and gluco-regulatory hormones, antropyloroduodenal pressures and fasting glucose, in healthy men. Neurogastroenterology and motility. Poster session presented at the meeting of 4th meeting of the Federation of Neurogastroenterology and Motility (FNM).

Year Citation
- Rose, B. (n.d.). Raw data.
DOI

2025     ACADI ECR Grant: Gut sweet sensing and non-nutritive sweeteners: a pathway to dysglycaemia? $40,000 

2025     The University of Adelaide, Faculty of Health and Medical Sciences – 2025 Small Equipment Funding Award: Refrigerated benchtop microcentrifuge $9,144 

2024     Blocking intestinal sweet taste for glycaemic benefits in type 2 diabetes. ADS-AstraZeneca Diabetes Research Grant. $20,000

2024     Optimising culturally safe and self-determined management of gestational diabetes mellitus among Aboriginal women in South Australia, assisting child health outcomes. HTSA MRFF Catalyst Grant. Elovaris R, Glover K, Llewellyn A, Jesudason D, Hampton K, Glass J, Collins H, Amos T, Davies C, Rose BD. $60,000

2020-4  Research Training Program Stipend, The University of Adelaide, $32,500 pa

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Investigating biological processes in intestinal sweet-sensing and glycaemic control, using pre-clinical mouse models Master of Clinical Science Master Full Time Ms Wei Theng Eng

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2025 - ongoing Principal Supervisor Interrogating the role of intestinal sweet sensing in blood glucose control The University of Adelaide - Honours - Emeshe Robson

Date Role Membership Country
2021 - ongoing Member American Society for Nutrition United States
2021 - ongoing Member Australian Diabetes Society Australia

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