Nicole Dmochowska

Research Interests

Molecular imaging (incl. electron microscopy and neutron diffraction) Nanomedicine

Dr Nicole Dmochowska

Research Fellow

Future Industries Institute

Future Industries Institute

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Nicole Dmochowska is an early-career Research Fellow whose research focuses on developing techniques and agents to enhance tumour mapping for improved cancer treatment, with a strong emphasis on clinical translation. She collaborates closely with Adelaide-based Ferronova to develop iron oxide contrast agents for improved tumour delineation on MRI. Notably, her work contributed to the development of second-generation FerroTrace-FAPi (WO/2022/241506, Mapping Nanoparticles), which is being prepared for first-in-human trials. In 2022, Nicole was awarded an MTPConnect Researcher Exchange and Development within Industry Fellowship, undertaking a year-long placement with Ferronova to gain industry expertise in clinical translation and commercialisation.
Nicole completed her PhD in Medicine at the University of Adelaide and the South Australian Health and Medical Research Institute in 2020 before joining the Future Industries Institute as a research associate. Her PhD focused on developing PET imaging tracers to target intestinal inflammation and fibrosis in a murine model of inflammatory bowel disease. During this time, she was awarded the William T. Southcott Nuclear Medicine Scholarship. From 2019 to 2024, Nicole served as a board member of the Australian Society of Molecular Imaging, contributing to the advancement of multidisciplinary molecular imaging research. She is also an Editorial Board Member for Discover Imaging (Springer Nature). Passionate about mentoring the next generation of women in STEM, Nicole is actively involved with the South Australian Academy for Gender Equity in STEM.

Date Type Title Institution Name Country Amount
2024 Award Finalist in science category, Women in Innovation (Winnovation) Winnovation Australia -
2020 Award Alavi-Mandell Award Society of Nuclear Medicine and Molecular Imaging United States -

Date Institution name Country Title
2016 University of Adelaide Australia Doctor of Philosophy
2015 - 2015 University of Adelaide Australia Bachelor of Health Science (Honours)
2012 - 2014 University of Adelaide Australia Bachelor of Science

Year Citation
2024 Badiee, P., Maritz, M. F., Dehghankelishadi, P., Dmochowska, N., & Thierry, B. (2024). Hydrophobic ion pairing and microfluidic nanoprecipitation enable efficient nanoformulation of a small molecule indolamine 2, 3-dioxygenase inhibitor immunotherapeutic. Bioengineering and Translational Medicine, 9(1, article no. e10599), 1-13.
DOI Europe PMC1
2023 Dehghankelishadi, P., Badiee, P., Maritz, M. F., Dmochowska, N., & Thierry, B. (2023). Bosutinib high density lipoprotein nanoformulation has potent tumour radiosensitisation effects. Journal of Nanobiotechnology, 21(102), 1-14.
DOI Scopus7 WoS7 Europe PMC5
2023 Dmochowska, N., Milanova, V., Mukkamala, R., Chow, K. K., Pham, N. T. H., Srinivasarao, M., . . . Thierry, B. (2023). Nanoparticles Targeted to Fibroblast Activation Protein Outperform PSMA for MRI Delineation of Primary Prostate Tumors. Small, 19(21), 2204956-1-2204956-14.
DOI Scopus7 WoS7 Europe PMC8
2022 Dmochowska, N., Milanova, V., Mukkamala, R., Chow, K. K., Pham, N. T. H., Srinivasarao, M., . . . Thierry, B. (2022). Nanoparticles targeted to fibroblast activation protein outperform PSMA for MRI delineation of primary prostate tumours.
DOI
2022 Dehghankelishadi, P., Maritz, M. F., Dmochowska, N., Badiee, P., Cheah, E., Kempson, I., . . . Thierry, B. (2022). Formulation of simvastatin within high density lipoprotein enables potent tumour radiosensitisation. Journal of Controlled Release, 346, 98-109.
DOI Scopus20 WoS17 Europe PMC11
2022 Badiee, P., Maritz, M. F., Dmochowska, N., Cheah, E., & Thierry, B. (2022). Intratumoral anti-PD-1 nanoformulation improves its biodistribution. ACS Applied Materials and Interfaces, 14(14), 15881-15893.
DOI Scopus10 WoS10 Europe PMC8
2020 Dmochowska, N., Tieu, W., Keller, M. D., Hollis, C. A., Campaniello, M. A., Mavrangelos, C., . . . Hughes, P. A. (2020). ⁸⁹Zr-pro-MMP-9 F(ab′)₂ detects colitis induced intestinal and kidney fibrosis. Scientific Reports, 10(1), 20372.
DOI Scopus10 WoS11 Europe PMC9
2019 Dmochowska, N., Tieu, W., Keller, M. D., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., . . . Hughes, P. A. (2019). Immuno-PET of Innate Immune Markers CD11b and IL-1β Detects Inflammation in Murine Colitis. Journal of nuclear medicine : Official publication, Society of Nuclear Medicine, 60(6), 858-863.
DOI Scopus30 WoS28 Europe PMC27
2019 Wardill, H. R., Choo, J. M., Dmochowska, N., Mavrangelos, C., Campaniello, M. A., Bowen, J. M., . . . Hughes, P. A. (2019). Acute colitis drives tolerance by persistently altering the epithelial barrier and innate and adaptive immunity. Inflammatory Bowel Diseases, 25(7), 1196-1207.
DOI Scopus13 WoS12 Europe PMC10
2018 Dmochowska, N., Wardill, H., & Hughes, P. (2018). Advances in imaging specific mediators of inflammatory bowel disease. International Journal of Molecular Sciences, 19(9), 2471-1-2471-13.
DOI Scopus43 WoS30 Europe PMC26

Year Citation
2022 Dmochowska, N., Milanova, V., Shetty, A., Mukkamala, R., Srinivasarao, M., Walser, E., . . . Thierry, B. (2022). FIBROBLAST ACTIVATION PROTEIN-SPECIFIC MRI PROVIDES IMPROVED TUMOUR MAPPING IN AN ORTHOTOPIC MODEL OF PROSTATE CANCER COMPARED TO PROSTATE SPECIFIC MEMBRANE ANTIGEN. In JOURNAL OF UROLOGY Vol. 207 (pp. E101-E102). LIPPINCOTT WILLIAMS & WILKINS.
2022 Dmochowska, N., Milanova, V., Shetty, A., Mukkamala, R., Srinivasarao, M., Walser, E., . . . Thierry, B. (2022). FIBROBLAST ACTIVATION PROTEIN-SPECIFIC MRI PROVIDES IMPROVED TUMOUR MAPPING IN AN ORTHOTOPIC MODEL OF PROSTATE CANCER COMPARED TO PROSTATE SPECIFIC MEMBRANE ANTIGEN. In JOURNAL OF UROLOGY Vol. 207 (pp. E101). LA, New Orleans: LIPPINCOTT WILLIAMS & WILKINS.
2020 Dmochowska, N., Tieu, W., Keller, M. D., Hollis, C., Campaniello, M., Mavrangelos, C., . . . Hughes, P. (2020). Detection of colitis induced intestinal and kidney fibrosis using α-pro-MMP9 immuno-PET. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 32 (pp. 1 page). WILEY.
2018 Hughes, P., Wardill, H., Choo, J., Dmochowska, N., Campaniello, M., Mavrangelos, C., . . . Rogers, G. (2018). Acute colitis chronically alters epithelial barrier and adaptive and innate immune responses to subsequent colitis re-activation independently of shifts in microbiota composition. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 30 (pp. 1 page). WILEY.

Year Citation
2018 Dmochowska, N., Campaniello, M., Mavrangelos, C., Wardill, H., Takhar, P., Keller, M., . . . Hughes, P. (2018). "In vivo" PET imaging of innate immune responses in murine DSS colitis. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2018 Hughes, P., Wardill, H., Dmochowska, N., Mavrangelos, C., Campaniello, M., Bowen, J., . . . Andrews, J. (2018). Proteolytic activation of IL-1 beta impairs epithelial barrier integrity in the ulcerative colitis lumen. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Brisbane, Qld: Wiley.
2017 Wardill, H., Bowen, J., Dmochowska, N., Campaniello, M., Mavrangelos, C., Holloway, R., . . . Hughes, P. (2017). Faecal supernatants from diarrhoea predominant Irritable Bowel Syndrome (IBS) patients disrupt colonic epithelial barrier function and directly activate colo-rectal afferent nerves. Poster session presented at the meeting of Abstracts of the NeuroGASTRO 2017 Congress, as published in Neurogastroenterology and Motility. Cork, Ireland: Wiley.
DOI
2017 Wardill, H. R., Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Bowen, J. M., Andrews, J. M., . . . Hughes, P. A. (2017). Fecal supernatants from active ulcerative colitis patients impair colonic epithelial barrier integrity and activate pelvic mucosal extrinsic afferent nerves. Poster session presented at the meeting of FASEB Journal. Chicago, IL: Federation of American Societies for Experimental Biology.

Year Citation
2022 Thierry, B., Nelson, M. R. M., Milanova, V., Dmochowska, N., Pham, T. H. N., & Hawkett, B. S. (2022). WO2022241506, Mapping nanoparticles.

  • Development and preclinical validation of a laparoscopic magnetometer probe based on quantum sensors for intraoperative mapping of the spread of gastrointestinal tumours, Australia's Economic Accelerator Ignite Grant, 27/05/2025 - 26/05/2026

  • Preclinical investigation of an ultrabright indocyanine green nanoformulation towards improved intraoperative fluorescence-guided surgery of pancreatic tumours, Tour de Cure Ltd, 01/01/2024 - 04/09/2025

  • Preclinical validation of a new molecular magnetic resonance imaging of glioblastoma towards improved image-guided treatment, Tour de Cure Ltd, 01/07/2023 - 01/07/2024

  • FAPi-MRI towards Better target delineation of high-grade Gliomas, Neurosurgical Research Foundation, 30/08/2021 - 31/08/2022

Date Role Research Topic Program Degree Type Student Load Student Name
2023 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mr Jaco Van Rooyen
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Tesi Liu
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Luke Bredberg
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Jalil Charmi

Date Role Board name Institution name Country
2021 - 2023 Secretary Australian Society of Molecular Imaging Australian Society of Molecular Imaging Australia
2019 - 2021 Board Member Australian Society of Molecular Imaging Australian Society of Molecular Imaging Australia

Date Role Editorial Board Name Institution Country
2024 - ongoing Board Member Discover Imaging Springer Nature (United States) Australia

Date Engagement Type Partner Name
2019 - ongoing Collaboration Ferronova

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