Neil Langlois

School of Biomedicine

Faculty of Health and Medical Sciences


Consultant forensic pathologist. UK trained and qualified in medicine. Trained and qualified in anatomical and forensic pathology. Consultant since 1999 in NSW, moved to Adelaide in 2008. Interest in estimating age of wounds, particularly bruises. Also, improving the evidence base for forensic pathology practice.

Areas of interest:

- Data extraction and analysis:  projects requiring extraction of information from autopsy reports from coronial post-mortem examinations for critical analysis of trends and incidence of causes of death.

- Determining the age of bruises : projects using experimental models and coronial postmortem tissue

- Ferroptosis: Resolution of a bruise requires macrophages to break down haemoglobin; the first step liberates an iron at (Fe 2+). Does this promote ferroptosis or is the iron oxidised and stored before ferroptosis occurs?

- Cell culture simulation of bruises: previous work has shown that macrophages will take up and breakdown red blood cells in culture. This would provide a model system to investigate the products of the resolution process of bruises and the potential for ferroptpsis.

 - Studies to examine the use of alternate light sources to enhance the visual appearance of bruises: work so far has used a model system representing a fresh bruise (by injection of blood). These previously published studies could be expanded by replicating old bruises (by using a mixture of bilirubin, ferritin and blood). Investigation is also required to compare visual assessment of bruises using alternate light source illumination with the results using photography.

 - Post-mortem radiology: coming soon, area under development

 

I have supervised a number of students to successful honours and PhD level. I aim to make each project have a publishable outcome.

Project work conducted at Forensic Science requires a National Police Clearance for the period of the project.

Faculty of Health and Medical Sciences 

Topics in Forensic Science


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