Marcus Wagstaff

School of Medicine

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


A/Professor Marcus Wagstaff BSc, MBBS, PhD, FRCS(Plast), FRACSMarcus is a Specialist Plastic and Reconstructive Surgeon, Head of Unit of the Adult Burns Service at the Royal Adelaide Hospital (RAH), Associate Professor affiliated to the University of Adelaide Faculty of Health and Medical Sciences, and Head of the RAH Skin Engineering Laboratory. He obtained his medical degree and PhD in molecular pathology at University College London, trained in plastic and reconstructive surgery in the UK, and has been working as a consultant at the RAH since 2010.His surgical interests include breast reconstruction after cancer, burns surgery, microsurgery, cosmetic breast surgery, body contouring, hand surgery, skin cancer excision and reconstruction, and trauma. He has research interests in skin culture, wounds, dermal substitutes, and scar management. He is a qualified PhD supervisor for the University of Adelaide and an examiner for the FRACS exam. Whilst providing an essential epidermal cell expansion and delivery service to supplement skin grafts in burns patients of South Australia, the RAH Skin Engineering Laboratory carries out focused translational research on laboratory-grown autologous composite skin culture (dermis and epidermis). The work of Dr Bronwyn Dearman is pioneering this tissue engineering technology for use in extensive burn-related and surgical wounds, with the goal of negating the need for surgical skin grafts.

A/Prof Wagstaff's doctoral research approached the question of whether overexpression of the heat shock proteins can protect neurons from the stresses of heat shock, ischaemia and apoptotic stimuli, an enquiry that demanded an understanding of the principles and problems associated with gene therapy - including vectors, delivery, and transgene expression -  as well as knowledge of herpes simplex virology, gene activation, the cellular response to stress and the role of molecular chaperones. As a PhD candidate, A/Prof Wagstaff became experienced in both basic and specialised molecular and cellular biology and virology techniques and developed more general research skills such as protocol development, data compilation, statistical analysis and interpretation, and manuscript preparation.

A/Prof Wagstaff has worked collaboratively with Prof John Greenwood in the Burns Unit of the Royal Adelaide Hospital in developing a novel dermal scaffold for cultured composite skin application in burns patients. During its development, they conducted the following four HREC approved case series:

Year Series Overview Project Details

2012

Short term implantation of novel biodegradable polyurethane foam in a randomised controlled trial as a negative pressure wound therapy dressing for decubitus ulcers.

  • 16 patients
  • 20 ulcers
2013 Long term implantation of novel biodegradable polyurethane foam (biodegradable temporising matrix – BTM) as a dermal scaffold for free flap donor site reconstruction.
  • 10 patients
2014 Long term implantation of an optimised, modified BTM as a dermal scaffold for free flap donor site reconstruction.
  • 10 patients
2014 Use of the BTM as a dermal scaffold for major burn reconstruction
  • 5 patients

Date Position Institution name
2020 - ongoing Clinical Associate Professor University of Adelaide
2020 - ongoing Head of Unit Royal Adelaide Hospital
2017 - ongoing Consultant Plastic and Reconstructive Surgeon Advanced Plastic and Cosmetic Surgery
2012 - ongoing Consultant Plastic and Reconstructive Staff Specialist Royal Adelaide Hospital
2011 - 2012 Senior Registrar / Supervised Consultant Royal Adelaide Hospital
2010 - 2011 Microsurgical Fellow Royal Adelaide Hospital

Language Competency
English Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2012 Royal Australasian College of Surgeons Australia FRACS in Plastic Surgery
2009 Postgraduate Medical Education and Training Board (United Kingdom) United Kingdom Certificate of Completion of Training in Plastic Surgery
2009 Royal College of Surgeons of England United Kingdom FRCS (Plast)
2002 Royal College of Surgeons of England United Kingdom MRCS
1999 University College London United Kingdom MBBS
1997 University College London United Kingdom PhD (Molecular Pathology)
1994 University College London United Kingdom Bachelor of Science (Immunology) with First Class Honours

Year Citation
2025 Vo, V., Haidari, H., Cowin, A. J., Wagstaff, M., Dearman, B., & Kopecki, Z. (2025). Dermal Substitutes for Clinical Management of Severe Burn Injuries: Current and Future Perspectives. Advanced Therapeutics, 8(3), 20 pages.
DOI Scopus2 WoS2
2025 Moran, H., Koh, E., Concannon, E., & Wagstaff, M. (2025). High voltage hobby; electrical burn following fractal wood burning: A case report. Jpras Open, 44, 129-132.
DOI
2025 Dowling, S., Kurmis, R., Gauro, J., Chapple, L. A., Coghlan, P., Concannon, E., . . . Hill, A. M. (2025). Energy expenditure following biodegradable dermal matrix application in severe burn injury: A pilot study. Clinical Nutrition ESPEN, 68, 71-80.
DOI
2025 Klotz, T., Moran, H., Vu, P., Maddern, G., & Wagstaff, M. (2025). Commonly recommended moisturising products effect on transepidermal water loss and hydration in a scar model. Burns, 51(8), 107629.
DOI
2024 Dounas, G. D., Willet, J. W., Alvaro, A. I., Jennings, M. P., Van de Ven, L., & Wagstaff, M. J. D. (2024). The importance of ward-based education in the postoperative assessment of free flaps. Australasian Journal of Plastic Surgery, 7(2), 1-6.
DOI
2024 Schmitt, B., Moore, L., Heath, K., Concannon, E., & Wagstaff, M. (2024). Multi-disciplinary mass burn casualty simulation exercise. Burns, 50(9), 12 pages.
DOI Scopus2 WoS2 Europe PMC1
2023 Concannon, E., Damkat-Thomas, L., Rose, E., Coghlan, P., Solanki, N., & Wagstaff, M. (2023). Use of a synthetic dermal matrix for reconstruction of 55 patients with non-graftable wounds and management of complications. Journal of Burn Care & Research, 44(4), 894-904.
DOI Scopus17 WoS13 Europe PMC12
2023 Bedrikovetski, S., Traeger, L., Jay, A. A., Oehler, M. K., Cho, J., Wagstaff, M., . . . Sammour, T. (2023). Is preoperative sarcopenia associated with postoperative complications after pelvic exenteration surgery?. Langenbeck's archives of surgery, 408(1), 12 pages.
DOI Scopus2 WoS1 Europe PMC1
2023 Lo, C. H., Wagstaff, M. J. D., Barker, T. M., Damkat-Thomas, L., Salerno, S., Holden, D., . . . Cleland, H. (2023). Long-term scarring outcomes and safety of patients treated with NovoSorbⓇ Biodegradable Temporizing Matrix (BTM): An observational cohort study. Jpras Open, 37, 42-51.
DOI Scopus9 WoS7 Europe PMC7
2023 Wagstaff, M. (2023). Burns workforce planning. Australasian Journal of Plastic Surgery, 6(1), 1-3.
DOI
2023 De Decker, I., Klotz, T., Vu, P., Hoeksema, H., De Mey, K., Beeckman, A., . . . Claes, K. E. Y. (2023). Influence of Moisturizers on Skin Microcirculation: An Assessment Study Using Laser Speckle Contrast Imaging. Journal of Personalized Medicine, 13(10), 1507.
DOI Scopus4 WoS2 Europe PMC2
2023 Concannon, E., Damkat Thomas, L., Kerr, L., Damkat, I., Reddi, B., Greenwood, J. E., . . . Wagstaff, M. J. D. (2023). Review of Indications for Endotracheal Intubation in Burn Patients with Suspected Inhalational Injury. European Burn Journal, 4(2), 163-172.
DOI Scopus2 WoS1
2022 Kuang, B., Pena, G., Cowled, P., Fitridge, R., Greenwood, J., Wagstaff, M., & Dawson, J. (2022). Use of Biodegradable Temporising Matrix (BTM) in the reconstruction of diabetic foot wounds: A pilot study.. Scars, burns & healing, 8, 20595131221122272.
DOI Europe PMC8
2022 Barker, T., Wagstaff, M., Ricketts, S., & Bruscino-Raiola, F. (2022). Use of a bilayer biodegradable synthetic dermal matrix for the management of defects arising from necrotising fasciitis. Journal of Wound Care, 31(9), 724-732.
DOI Scopus2 WoS3 Europe PMC1
2022 Lo, C. H., Brown, J. N., Dantzer, E. J. G., Maitz, P. K. M., Vandervord, J. G., Wagstaff, M. J. D., . . . Cleland, H. (2022). Wound healing and dermal regeneration in severe burn patients treated with NovoSorb® Biodegradable Temporising Matrix: A prospective clinical study. Burns, 48(3), 529-538.
DOI Scopus49 WoS46 Europe PMC38
2022 Klotz, T., Ibrahim, A., Maddern, G., Caplash, Y., & Wagstaff, M. (2022). Devices measuring transepidermal water loss: A systematic review of measurement properties.. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 28(4), 497-539.
DOI Scopus25 WoS25 Europe PMC14
2022 Traeger, L., Bedrikovetski, S., Oehler, M. K., Cho, J., Wagstaff, M., Harbison, J., . . . Sammour, T. (2022). Short-term outcomes following development of a dedicated pelvic exenteration service in a tertiary centre.. ANZ J Surg, 92(10), 2620-2627.
DOI Scopus5 WoS5 Europe PMC4
2021 Stefani, K., Wagstaff, M. J. D., Damkat, I., & Greenwood, J. E. (2021). Mortality data 2004–2019: an audit of the Royal Adelaide Hospital Adult Burn Service. ANZ Journal of Surgery, 91(1-2), 77-82.
DOI Scopus3 WoS1 Europe PMC2
2021 Schmitt, B., Heath, K., Kurmis, R., Klotz, T., Wagstaff, M. J. D., & Greenwood, J. (2021). Early physiotherapy experience with a biodegradable polyurethane dermal substitute: Therapy guidelines for use. Burns, 47(5), 1074-1083.
DOI Scopus11 WoS9 Europe PMC7
2021 Klotz, T., Maddern, G., Caplash, Y., & Wagstaff, M. (2021). Devices measuring transepidermal water loss of the skin. JBI Evidence Synthesis, 19(10), 2893-2903.
DOI Scopus3 WoS3 Europe PMC3
2019 Damkat-Thomas, L., Greenwood, J. E., & Wagstaff, M. J. D. (2019). A Synthetic Biodegradable Temporising Matrix in Degloving Lower Extremity Trauma Reconstruction: A Case Report. Plastic and Reconstructive Surgery Global Open, 7(4), 4 pages.
DOI Scopus41 WoS34 Europe PMC32
2019 Wagstaff, M. J. D., Salna, I. M., Caplash, Y., & Greenwood, J. E. (2019). Biodegradable Temporising Matrix (BTM) for the reconstruction of defects following serial debridement for necrotising fasciitis: A case series. Burns Open, 3(1), 12-30.
DOI Scopus57
2018 Greenwood, J. E., Schmitt, B. J., & Wagstaff, M. J. D. (2018). Experience with a synthetic bilayer Biodegradable Temporising Matrix in significant burn injury. Burns Open, 2(1), 17-34.
DOI Scopus85
2017 Wagstaff, M. J., Caplash, Y., & Greenwood, J. E. (2017). Reconstruction of an Anterior Cervical Necrotizing Fasciitis Defect Using a Biodegradable Polyurethane Dermal Substitute.. Eplasty, 17, e3.
Europe PMC19
2016 Greenwood, J. E., Wagstaff, M. J. D., Rooke, M., & Caplash, Y. (2016). Reconstruction of Extensive Calvarial Exposure After Major Burn Injury in 2 Stages Using a Biodegradable Polyurethane Matrix.. Eplasty, 16, e17.
Europe PMC24
2016 Iyer, K., Dearman, B. L., Wagstaff, M. J., & Greenwood, J. E. (2016). A Novel Biodegradable Polyurethane Matrix for Auricular Cartilage Repair: An In Vitro and In Vivo Study. Journal of Burn Care and Research, 37(4), e353-e364.
DOI Scopus14 WoS13 Europe PMC11
2016 Smith, N. W. S., Overland, J., & Wagstaff, M. (2016). Informed consent practices by junior medical officers: A cross-sectional study. ANZ Journal of Surgery, 86(1-2), 10-11.
DOI Scopus4 WoS5 Europe PMC5
2015 Mistry, R., Caplash, Y., Giri, P., Kearney, D., & Wagstaff, M. (2015). Thoracic outlet syndrome following breast implant rupture. Plastic and reconstructive surgery. Global open, 3(3), e331-1-e331-4.
DOI Scopus8 WoS7 Europe PMC7
2015 Wagstaff, M., Schmitt, B., Coghlan, P., Finkemeyer, J., Caplash, Y., & Greenwood, J. (2015). A biodegradable polyurethane dermal matrix in reconstruction of free flap donor sites: a pilot study. Eplasty, 15, 102-118.
Europe PMC31
2015 Wagstaff, M., Schmitt, B., Caplash, Y., & Greenwood, J. (2015). Free Flap Donor Site Reconstruction: A Prospective Case Series Using an Optimized Polyurethane Biodegradable Temporizing Matrix.. Eplasty, 15, 231-248.
Europe PMC21
2014 Wagstaff, M., Driver, S., Coghlan, P., & Greenwood, J. (2014). A randomized, controlled trial of negative pressure wound therapy of pressure ulcers via a novel polyurethane foam. Wound Repair and Regeneration, 22(2), 205-211.
DOI Scopus37 WoS32 Europe PMC25
2013 Mistry, R., Tsimiklis, C., Wagstaff, M., Abou-Hamden, A., & Caplash, Y. (2013). Secondary Reconstruction of Recurrent Primary Intraosseous Meningioma of the Calvarium Using a Fasciocutaneous Anterolateral Thigh Free Flap. Neuroscience and Medicine, 04(04), 280-283.
DOI
2012 Pilkington, K., Wagstaff, M., & Greenwood, J. (2012). Prevention of gastrointestinal bleeding due to stress ulceration: a review of current literature. Anaesthesia and Intensive Care, 40(2), 253-259.
DOI Scopus18 WoS19 Europe PMC12
2012 Solanki, N. S., Greenwood, J. E., Wagstaff, M. J. D., & Franchi, B. F. A. L. (2012). Length of stay of elderly patients in an acute burns unit: has the pilot appointment of a geriatrician to the service made a difference?. Journal of Burn Care and Research, 33(3), e179.
DOI Scopus3 WoS2 Europe PMC1
2012 Greenwood, J. E., Wagstaff, M. J. D., Mackie, I. P., & Mustoe, T. A. (2012). Silicone action in the open wound: a hypothesis. Journal of Burn Care and Research, 33(1), e17-e20.
DOI Scopus6 WoS4 Europe PMC3
2011 Chang, A. C., Watson, K. M., Aston, T. L., Wagstaff, M. J., & Greenwood, J. E. (2011). Depilatory wax burns: experience and investigation.. Eplasty, 11, e25.
Europe PMC1
2010 Rozen, W. M., Whitaker, I. S., Audolfsson, T., Jakobsson, O. P., Wagstaff, M. J. D., & Acosta, R. (2010). Banking a DIEP flap in high-risk patients: A new technique during unilateral DIEP harvest. Plastic and Reconstructive Surgery, 125(3), 114E-115E.
DOI Scopus3 WoS5 Europe PMC1
2010 Wagstaff, M. J. D. (2010). BASO/BAPRAS interface fellowship in oncoplastic surgery of the breast at Sheffield teaching hospitals NHS trust. Annals of Plastic Surgery, 65(6), 517-518.
DOI
2010 Rozen, W. M., Whitaker, I. S., Wagstaff, M. J. D., Audolfsson, T., & Acosta, R. (2010). Buried free flaps for breast reconstruction: A new technique using the cook-swartz implantable doppler probe for postoperative monitoring. Plastic and Reconstructive Surgery, 125(4), 171E-172E.
DOI Scopus11 WoS8 Europe PMC7
2010 Acosta, R., Enajat, M., Rozen, W. M., Smit, J. M., Wagstaff, M. J. D., Whitaker, I. S., & Audolfsson, T. (2010). Performing two DIEP flaps in a working day: an achievable and reproducible practice. Journal of Plastic Reconstructive and Aesthetic Surgery, 63(4), 648-654.
DOI Scopus35 WoS30 Europe PMC23
2010 Rozen, W. M., Wagstaff, M. J. D., Grinsell, D., Le Roux, C. M., & Ashton, M. W. (2010). The course of anterolateral thigh perforators does not correlate between sides of the body: The role for preoperative imaging. Plastic and Reconstructive Surgery, 125(3), 132E-134E.
DOI Scopus4 WoS2 Europe PMC3
2009 Mavrogordato, A. E., Wagstaff, M. J. D., Fletcher, A. J. P., Wilson, D. I., & Jayamaha, J. E. L. (2009). A novel method to treat hyperthermia in a burns case: Use of a catheter-based heat exchange system. Burns, 35(1), 141-145.
DOI Scopus9 WoS5 Europe PMC6
2009 Wagstaff, M. J. D., Rozen, W. M., Whitaker, I. S., Schneider, T. N., Audolfsson, T., & Acosta, R. (2009). Kirschner wires: a novel technique to assist abdominal closure utilising the viscoelastic properties of skin. Journal of Plastic Reconstructive and Aesthetic Surgery, 62(5), e115-e116.
DOI Scopus2 WoS2 Europe PMC1
2009 Rozen, W. M., Ashton, M. W., Whitaker, I. S., Wagstaff, M. J. D., & Acosta, R. (2009). The financial implications of computed tomographic angiography in diep flap surgery: A cost analysis. Microsurgery, 29(2), 168-169.
DOI Scopus36 WoS34 Europe PMC30
2009 Wagstaff, M. J. D., Rozen, W. M., Whitaker, I. S., Enajat, M., Audolfsson, T., & Acosta, R. (2009). Perineal and posterior vaginal wall reconstruction with superior and inferior gluteal artery perforator flaps. Microsurgery, 29(8), 626-629.
DOI Scopus58 WoS50 Europe PMC46
2009 Audolfsson, T., Rozen, W. M., Wagstaff, M. J. D., Whitaker, I. S., & Acosta, R. (2009). A reliable and aesthetic technique for cephalic vein harvest in DIEP flap surgery. Journal of Reconstructive Microsurgery, 25(5), 319-321.
DOI Scopus9 WoS10 Europe PMC6
2007 Wagstaff, M. J. D., Shah, M., McGrouther, D. A., & Latchman, D. S. (2007). The heat shock proteins and plastic surgery. Journal of Plastic Reconstructive and Aesthetic Surgery, 60(9), 974-982.
DOI Scopus16 WoS15 Europe PMC9
2006 Milner, C. S., Wagstaff, M. J. D., & Rose, G. K. (2006). Compartment syndrome of multiple limbs: An unusual presentation. Journal of Plastic Reconstructive and Aesthetic Surgery, 59(11), 1251-1252.
DOI Scopus6 WoS4 Europe PMC3
2006 Wagstaff, M. J. D., Sankar, T. K., & Ward, D. J. (2006). Describing the 'dog ear' - a novel method. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 88(4), 415-416.
DOI
2004 Wagstaff, M. J. D., Raurell, A., & Perks, A. G. B. (2004). Multicentric extra-abdominal desmoid tumours. British Journal of Plastic Surgery, 57(4), 362-365.
DOI Scopus19 WoS13 Europe PMC14
1999 Brar, B. K., Stephanou, A., Wagstaff, M. J. D., Coffin, R. S., Marber, M. S., Engelmann, G., & Latchman, D. S. (1999). Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. Journal of Molecular and Cellular Cardiology, 31(1), 135-146.
DOI Scopus120 WoS109 Europe PMC93
1999 Wagstaff, M. J. D., Collaço-Moraes, Y., Smith, J., De Belleroche, J. S., Coffin, R. S., & Latchman, D. S. (1999). Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. Journal of Biological Chemistry, 274(8), 5061-5069.
DOI Scopus196 WoS189 Europe PMC159
1998 Wagstaff, M. J. D. (1998). Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. European Journal of Neuroscience, 10(11), 3343-3350.
DOI Scopus35 WoS33 Europe PMC26
1998 Coffin, R. S., Thomas, S. K., Thomas, N. S. B., Lilley, C. E., Pizzey, A. R., Griffiths, C. H., . . . Latchman, D. S. (1998). Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry. Gene Therapy, 5(5), 718-722.
DOI Scopus35 WoS29 Europe PMC22
1998 Wagstaff, M. J. D., Lilley, C. E., Smith, J., Robinson, M. J., Coffin, R. S., & Latchman, D. S. (1998). Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo. Gene Therapy, 5(11), 1566-1570.
DOI Scopus26 WoS22 Europe PMC15
1996 Wagstaff, M. J. D., Collaço-Moraes, Y., Aspey, B. S., Coffin, R. S., Harrison, M. J. G., Latchman, D. S., & De Belleroche, J. S. (1996). Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Molecular Brain Research, 42(2), 236-244.
DOI Scopus53 WoS55 Europe PMC50
1995 VYAKARNAM, A., MATEAR, P. M., MARTIN, S. J., & WAGSTAFF, M. (1995). TH1 CELLS SPECIFIC FOR HIV-1 GAG P24 ARE LESS EFFICIENT THAN TH0 CELLS IN SUPPORTING HIV REPLICATION, AND INHIBIT VIRUS-REPLICATION IN TH0 CELLS. IMMUNOLOGY, 86(1), 85-96.
WoS34 Europe PMC27

Year Citation
2011 Raftery, A. T., Delbridge, M. S., & Wagstaff, M. J. D. (2011). Churchill's Pocketbook of Surgery E-Book. Elsevier Health Sciences.

Year Citation
2025 Wagstaff, M. J. D., & Low, N. (2025). Experience with a Synthetic Bilayer Biodegradable Temporising Matrix in Significant Burn Injury. In 50 Landmark Papers Every Plastic Surgeon Should Know (pp. 68-77). CRC Press.
DOI
2016 Greenwood, J., & Wagstaff, M. (2016). The use of Biodegradable Polyurethane in the Development of Dermal Scaffolds. In S. Cooper, & J. Guan (Eds.), Advances in Polyurethane Biomaterials (pp. 631-662). United Kingdom: Elsevier.
DOI Scopus10
2010 Wagstaff, M. J. D., Reed, M. W. R., & Caddy, C. M. (2010). Breast reconstruction. In Management of Breast Cancer in Older Women (pp. 213-229). Springer London.
DOI

Date Role Research Topic Program Degree Type Student Load Student Name
2020 Co-Supervisor Hypertrophic scar measures relationship to transepidermal water loss, and the effect of generic moisturisers on transepidermal water loss. Doctor of Philosophy Doctorate Part Time Ms Tanja Klotz

Date Role Committee Institution Country
2021 - ongoing Member Fellowship Examination Committee in Plastic and Reconstructive Surgery Royal Australasian College of Surgeons Australia

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