Marcus Wagstaff
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
A/Professor Marcus Wagstaff BSc, MBBS, PhD, FRCS(Plast), FRACS
Marcus is a Specialist Plastic and Reconstructive Surgeon, Head of Unit of the Adult Burns Service at the Royal Adelaide Hospital (RAH), Associate Professor affiliated to the University of Adelaide Faculty of Health and Medical Sciences, and Head of the RAH Skin Engineering Laboratory.
He obtained his medical degree and PhD in molecular pathology at University College London, trained in plastic and reconstructive surgery in the UK, and has been working as a consultant at the RAH since 2010.
His surgical interests include breast reconstruction after cancer, burns surgery, microsurgery, cosmetic breast surgery, body contouring, hand surgery, skin cancer excision and reconstruction, and trauma.
He has research interests in skin culture, wounds, dermal substitutes, and scar management. He is a qualified PhD supervisor for the University of Adelaide and an examiner for the FRACS exam.
Whilst providing an essential epidermal cell expansion and delivery service to supplement skin grafts in burns patients of South Australia, the RAH Skin Engineering Laboratory carries out focused translational research on laboratory-grown autologous composite skin culture (dermis and epidermis). The work of Dr Bronwyn Dearman is pioneering this tissue engineering technology for use in extensive burn-related and surgical wounds, with the goal of negating the need for surgical skin grafts.
A/Prof Wagstaff's doctoral research approached the question of whether overexpression of the heat shock proteins can protect neurons from the stresses of heat shock, ischaemia and apoptotic stimuli, an enquiry that demanded an understanding of the principles and problems associated with gene therapy - including vectors, delivery, and transgene expression - as well as knowledge of herpes simplex virology, gene activation, the cellular response to stress and the role of molecular chaperones. As a PhD candidate, A/Prof Wagstaff became experienced in both basic and specialised molecular and cellular biology and virology techniques and developed more general research skills such as protocol development, data compilation, statistical analysis and interpretation, and manuscript preparation.
A/Prof Wagstaff has worked collaboratively with Prof John Greenwood in the Burns Unit of the Royal Adelaide Hospital in developing a novel dermal scaffold for cultured composite skin application in burns patients. During its development, they conducted the following four HREC approved case series:
Year | Series Overview | Project Details |
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2012 |
Short term implantation of novel biodegradable polyurethane foam in a randomised controlled trial as a negative pressure wound therapy dressing for decubitus ulcers. |
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2013 | Long term implantation of novel biodegradable polyurethane foam (biodegradable temporising matrix – BTM) as a dermal scaffold for free flap donor site reconstruction. |
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2014 | Long term implantation of an optimised, modified BTM as a dermal scaffold for free flap donor site reconstruction. |
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2014 | Use of the BTM as a dermal scaffold for major burn reconstruction |
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Appointments
Date Position Institution name 2020 - ongoing Clinical Associate Professor University of Adelaide 2020 - ongoing Head of Unit Royal Adelaide Hospital 2017 - ongoing Consultant Plastic and Reconstructive Surgeon Advanced Plastic and Cosmetic Surgery 2012 - ongoing Consultant Plastic and Reconstructive Staff Specialist Royal Adelaide Hospital 2011 - 2012 Senior Registrar / Supervised Consultant Royal Adelaide Hospital 2010 - 2011 Microsurgical Fellow Royal Adelaide Hospital -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 2012 Royal Australasian College of Surgeons Australia FRACS in Plastic Surgery 2009 Postgraduate Medical Education and Training Board (United Kingdom) United Kingdom Certificate of Completion of Training in Plastic Surgery 2009 Royal College of Surgeons of England United Kingdom FRCS (Plast) 2002 Royal College of Surgeons of England United Kingdom MRCS 1999 University College London United Kingdom MBBS 1997 University College London United Kingdom PhD (Molecular Pathology) 1994 University College London United Kingdom Bachelor of Science (Immunology) with First Class Honours -
Research Interests
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Journals
Year Citation 2024 Dounas, G. D., Willet, J. W., Alvaro, A. I., Jennings, M. P., Van de Ven, L., & Wagstaff, M. J. D. (2024). The importance of ward-based education in the postoperative assessment of free flaps. Australasian Journal of Plastic Surgery, 7(2), 1-6.
2024 Schmitt, B., Moore, L., Heath, K., Concannon, E., & Wagstaff, M. (2024). Multi-disciplinary mass burn casualty simulation exercise. Burns, 50(9), 12 pages.
2024 Wang, Y., Sapula, S. A., Whittall, J. J., Blaikie, J. M., Lomovskaya, O., & Venter, H. (2024). Identification and characterization of CIM-1, a carbapenemase that adds to the family of resistance factors against last resort antibiotics. Communications Biology, 7(1), 13 pages.
Scopus12024 Huang, B., Pang, L., Fu, A., Al-Sarawi, S., Abbott, D., & Gao, Y. (2024). Sponge Attack Against Multi-Exit Networks with Data Poisoning. IEEE Access, 12, 33843-33851.
Scopus12024 Xu, W., Smith, N., Ting, R., Soh, Q., Saeed, U., Farrell, M., . . . Chye, D. (2024). Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries. British Journal of Surgery, 111(1), znad421.
Scopus5 Europe PMC22024 Ma, Y., Lin, J., Li, M., Zhu, Y., Zhao, L., Liang, D., . . . Zhao, G. (2024). Effect of lignin on the formation of polycyclic aromatic hydrocarbons in smoked and grilled meat products. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 261, 7 pages.
2023 Concannon, E., Damkat-Thomas, L., Rose, E., Coghlan, P., Solanki, N., & Wagstaff, M. (2023). Use of a synthetic dermal matrix for reconstruction of 55 patients with non-graftable wounds and management of complications. Journal of Burn Care & Research, 44(4), 894-904.
Scopus9 WoS2 Europe PMC62023 Bedrikovetski, S., Traeger, L., Jay, A. A., Oehler, M. K., Cho, J., Wagstaff, M., . . . Sammour, T. (2023). Is preoperative sarcopenia associated with postoperative complications after pelvic exenteration surgery?. Langenbeck's archives of surgery, 408(1), 12 pages.
2023 Lo, C. H., Wagstaff, M. J. D., Barker, T. M., Damkat-Thomas, L., Salerno, S., Holden, D., . . . Cleland, H. (2023). Long-term scarring outcomes and safety of patients treated with NovoSorb<sup>Ⓡ</sup> Biodegradable Temporizing Matrix (BTM): An observational cohort study. JPRAS Open, 37, 42-51.
Scopus5 Europe PMC42023 Wagstaff, M. (2023). Burns workforce planning. Australasian Journal of Plastic Surgery, 6(1), 1-3.
2023 De Decker, I., Klotz, T., Vu, P., Hoeksema, H., De Mey, K., Beeckman, A., . . . Claes, K. E. Y. (2023). Influence of Moisturizers on Skin Microcirculation: An Assessment Study Using Laser Speckle Contrast Imaging. Journal of Personalized Medicine, 13(10), 1507.
2023 Concannon, E., Damkat Thomas, L., Kerr, L., Damkat, I., Reddi, B., Greenwood, J. E., . . . Wagstaff, M. J. D. (2023). Review of Indications for Endotracheal Intubation in Burn Patients with Suspected Inhalational Injury. European Burn Journal, 4(2), 163-172.
2022 Kuang, B., Pena, G., Cowled, P., Fitridge, R., Greenwood, J., Wagstaff, M., & Dawson, J. (2022). Use of Biodegradable Temporising Matrix (BTM) in the reconstruction of diabetic foot wounds: A pilot study.. Scars, burns & healing, 8, 20595131221122272.
Europe PMC42022 Barker, T., Wagstaff, M., Ricketts, S., & Bruscino-Raiola, F. (2022). Use of a bilayer biodegradable synthetic dermal matrix for the management of defects arising from necrotising fasciitis. Journal of Wound Care, 31(9), 724-732.
Scopus1 Europe PMC12022 Lo, C. H., Brown, J. N., Dantzer, E. J. G., Maitz, P. K. M., Vandervord, J. G., Wagstaff, M. J. D., . . . Cleland, H. (2022). Wound healing and dermal regeneration in severe burn patients treated with NovoSorb® Biodegradable Temporising Matrix: A prospective clinical study. Burns, 48(3), 529-538.
Scopus33 WoS15 Europe PMC172022 Klotz, T., Ibrahim, A., Maddern, G., Caplash, Y., & Wagstaff, M. (2022). Devices measuring transepidermal water loss: A systematic review of measurement properties.. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 28(4), 497-539.
Scopus15 WoS4 Europe PMC92022 Traeger, L., Bedrikovetski, S., Oehler, M. K., Cho, J., Wagstaff, M., Harbison, J., . . . Sammour, T. (2022). Short-term outcomes following development of a dedicated pelvic exenteration service in a tertiary centre.. ANZ J Surg, 92(10), 2620-2627.
Scopus5 WoS3 Europe PMC12022 Chan, D., Bennett, P. R., Lee, Y. S., Kundu, S., Teoh, T. G., Adan, M., . . . Sykes, L. (2022). Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response. Nature Communications, 13(1), 15 pages.
Scopus54 Europe PMC392021 Stefani, K., Wagstaff, M. J. D., Damkat, I., & Greenwood, J. E. (2021). Mortality data 2004–2019: an audit of the Royal Adelaide Hospital Adult Burn Service. ANZ Journal of Surgery, 91(1-2), 77-82.
Scopus2 Europe PMC22021 Schmitt, B., Heath, K., Kurmis, R., Klotz, T., Wagstaff, M. J. D., & Greenwood, J. (2021). Early physiotherapy experience with a biodegradable polyurethane dermal substitute: Therapy guidelines for use. Burns, 47(5), 1074-1083.
Scopus9 WoS4 Europe PMC42021 Klotz, T., Maddern, G., Caplash, Y., & Wagstaff, M. (2021). Devices measuring transepidermal water loss of the skin. JBI Evidence Synthesis, 19(10), 2893-2903.
Scopus2 WoS1 Europe PMC12019 Damkat-Thomas, L., Greenwood, J. E., & Wagstaff, M. J. D. (2019). A Synthetic Biodegradable Temporising Matrix in Degloving Lower Extremity Trauma Reconstruction: A Case Report. Plastic and Reconstructive Surgery - Global Open, 7(4), 4 pages.
Scopus33 WoS18 Europe PMC192019 Wagstaff, M. J. D., Salna, I. M., Caplash, Y., & Greenwood, J. E. (2019). Biodegradable Temporising Matrix (BTM) for the reconstruction of defects following serial debridement for necrotising fasciitis: A case series. Burns Open, 3(1), 12-30.
Scopus492018 Greenwood, J. E., Schmitt, B. J., & Wagstaff, M. J. D. (2018). Experience with a synthetic bilayer Biodegradable Temporising Matrix in significant burn injury. Burns Open, 2(1), 17-34.
Scopus732017 Wagstaff, M. J., Caplash, Y., & Greenwood, J. E. (2017). Reconstruction of an Anterior Cervical Necrotizing Fasciitis Defect Using a Biodegradable Polyurethane Dermal Substitute.. Eplasty, 17, e3.
Europe PMC142016 Greenwood, J. E., Wagstaff, M. J. D., Rooke, M., & Caplash, Y. (2016). Reconstruction of Extensive Calvarial Exposure After Major Burn Injury in 2 Stages Using a Biodegradable Polyurethane Matrix.. Eplasty, 16, e17.
Europe PMC232016 Iyer, K., Dearman, B. L., Wagstaff, M. J., & Greenwood, J. E. (2016). A Novel Biodegradable Polyurethane Matrix for Auricular Cartilage Repair: An In Vitro and In Vivo Study. Journal of Burn Care and Research, 37(4), e353-e364.
Scopus11 WoS9 Europe PMC62016 Smith, N. W. S., Overland, J., & Wagstaff, M. (2016). Informed consent practices by junior medical officers: A cross-sectional study. ANZ Journal of Surgery, 86(1-2), 10-11.
Scopus2 WoS22015 Mistry, R., Caplash, Y., Giri, P., Kearney, D., & Wagstaff, M. (2015). Thoracic outlet syndrome following breast implant rupture. Plastic and reconstructive surgery. Global open, 3(3), e331-1-e331-4.
Scopus4 WoS1 Europe PMC32015 Wagstaff, M., Schmitt, B., Coghlan, P., Finkemeyer, J., Caplash, Y., & Greenwood, J. (2015). A biodegradable polyurethane dermal matrix in reconstruction of free flap donor sites: a pilot study. Eplasty, 15, 102-118.
Europe PMC242015 Wagstaff, M., Schmitt, B., Caplash, Y., & Greenwood, J. (2015). Free Flap Donor Site Reconstruction: A Prospective Case Series Using an Optimized Polyurethane Biodegradable Temporizing Matrix.. Eplasty, 15, 231-248.
Europe PMC182014 Wagstaff, M., Driver, S., Coghlan, P., & Greenwood, J. (2014). A randomized, controlled trial of negative pressure wound therapy of pressure ulcers via a novel polyurethane foam. Wound Repair and Regeneration, 22(2), 205-211.
Scopus35 WoS26 Europe PMC192013 Mistry, R., Tsimiklis, C., Wagstaff, M., Abou-Hamden, A., & Caplash, Y. (2013). Secondary Reconstruction of Recurrent Primary Intraosseous Meningioma of the Calvarium Using a Fasciocutaneous Anterolateral Thigh Free Flap. Neuroscience and Medicine, 04(04), 280-283.
2012 Pilkington, K., Wagstaff, M., & Greenwood, J. (2012). Prevention of gastrointestinal bleeding due to stress ulceration: a review of current literature. Anaesthesia and Intensive Care, 40(2), 253-259.
Scopus18 WoS17 Europe PMC122012 Solanki, N. S., Greenwood, J. E., Wagstaff, M. J. D., & Franchi, B. F. A. L. (2012). Length of stay of elderly patients in an acute burns unit: has the pilot appointment of a geriatrician to the service made a difference?. Journal of Burn Care and Research, 33(3), e179.
Scopus2 WoS2 Europe PMC12012 Greenwood, J. E., Wagstaff, M. J. D., Mackie, I. P., & Mustoe, T. A. (2012). Silicone action in the open wound: a hypothesis. Journal of Burn Care and Research, 33(1), e17-e20.
Scopus5 WoS3 Europe PMC22011 Chang, A. C., Watson, K. M., Aston, T. L., Wagstaff, M. J., & Greenwood, J. E. (2011). Depilatory wax burns: experience and investigation.. Eplasty, 11, e25.
Europe PMC12010 Rozen, W. M., Whitaker, I. S., Audolfsson, T., Jakobsson, O. P., Wagstaff, M. J. D., & Acosta, R. (2010). Banking a DIEP flap in high-risk patients: A new technique during unilateral DIEP harvest. Plastic and Reconstructive Surgery, 125(3), 114E-115E.
Scopus3 WoS5 Europe PMC12010 Wagstaff, M. J. D. (2010). BASO/BAPRAS interface fellowship in oncoplastic surgery of the breast at Sheffield teaching hospitals NHS trust. Annals of Plastic Surgery, 65(6), 517-518.
2010 Rozen, W. M., Whitaker, I. S., Wagstaff, M. J. D., Audolfsson, T., & Acosta, R. (2010). Buried free flaps for breast reconstruction: A new technique using the cook-swartz implantable doppler probe for postoperative monitoring. Plastic and Reconstructive Surgery, 125(4), 171E-172E.
Scopus11 WoS6 Europe PMC52010 Acosta, R., Enajat, M., Rozen, W. M., Smit, J. M., Wagstaff, M. J. D., Whitaker, I. S., & Audolfsson, T. (2010). Performing two DIEP flaps in a working day: an achievable and reproducible practice. Journal of Plastic, Reconstructive and Aesthetic Surgery, 63(4), 648-654.
Scopus34 WoS25 Europe PMC152010 Rozen, W. M., Wagstaff, M. J. D., Grinsell, D., Le Roux, C. M., & Ashton, M. W. (2010). The course of anterolateral thigh perforators does not correlate between sides of the body: The role for preoperative imaging. Plastic and Reconstructive Surgery, 125(3), 132E-134E.
Scopus4 WoS2 Europe PMC22009 Mavrogordato, A. E., Wagstaff, M. J. D., Fletcher, A. J. P., Wilson, D. I., & Jayamaha, J. E. L. (2009). A novel method to treat hyperthermia in a burns case: Use of a catheter-based heat exchange system. Burns, 35(1), 141-145.
Scopus9 WoS4 Europe PMC42009 Wagstaff, M. J. D., Rozen, W. M., Whitaker, I. S., Schneider, T. N., Audolfsson, T., & Acosta, R. (2009). Kirschner wires: a novel technique to assist abdominal closure utilising the viscoelastic properties of skin. Journal of Plastic, Reconstructive and Aesthetic Surgery, 62(5), E115-E116.
Scopus2 WoS2 Europe PMC12009 Rozen, W. M., Ashton, M. W., Whitaker, I. S., Wagstaff, M. J. D., & Acosta, R. (2009). The financial implications of computed tomographic angiography in diep flap surgery: A cost analysis. Microsurgery, 29(2), 168-169.
Scopus34 WoS29 Europe PMC202009 Wagstaff, M. J. D., Rozen, W. M., Whitaker, I. S., Enajat, M., Audolfsson, T., & Acosta, R. (2009). Perineal and posterior vaginal wall reconstruction with superior and inferior gluteal artery perforator flaps. Microsurgery, 29(8), 626-629.
Scopus54 WoS44 Europe PMC292009 Audolfsson, T., Rozen, W. M., Wagstaff, M. J. D., Whitaker, I. S., & Acosta, R. (2009). A reliable and aesthetic technique for cephalic vein harvest in DIEP flap surgery. Journal of Reconstructive Microsurgery, 25(5), 319-321.
Scopus8 WoS9 Europe PMC32007 Wagstaff, M. J. D., Shah, M., McGrouther, D. A., & Latchman, D. S. (2007). The heat shock proteins and plastic surgery. Journal of Plastic, Reconstructive and Aesthetic Surgery, 60(9), 974-982.
Scopus16 WoS13 Europe PMC62006 Milner, C. S., Wagstaff, M. J. D., & Rose, G. K. (2006). Compartment syndrome of multiple limbs: An unusual presentation. Journal of Plastic, Reconstructive and Aesthetic Surgery, 59(11), 1251-1252.
Scopus5 WoS4 Europe PMC32006 Wagstaff, M. J. D., Sankar, T. K., & Ward, D. J. (2006). Describing the 'dog ear' - a novel method. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 88(4), 415-416.
2004 Wagstaff, M. J. D., Raurell, A., & Perks, A. G. B. (2004). Multicentric extra-abdominal desmoid tumours. British Journal of Plastic Surgery, 57(4), 362-365.
Scopus18 WoS11 Europe PMC111999 Brar, B. K., Stephanou, A., Wagstaff, M. J. D., Coffin, R. S., Marber, M. S., Engelmann, G., & Latchman, D. S. (1999). Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. Journal of Molecular and Cellular Cardiology, 31(1), 135-146.
Scopus117 WoS108 Europe PMC781999 Wagstaff, M. J. D., Collaço-Moraes, Y., Smith, J., De Belleroche, J. S., Coffin, R. S., & Latchman, D. S. (1999). Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. Journal of Biological Chemistry, 274(8), 5061-5069.
Scopus195 WoS188 Europe PMC1451998 Wagstaff, M. J. D. (1998). Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. European Journal of Neuroscience, 10(11), 3343-3350.
Scopus35 WoS33 Europe PMC251998 Coffin, R. S., Thomas, S. K., Thomas, N. S. B., Lilley, C. E., Pizzey, A. R., Griffiths, C. H., . . . Latchman, D. S. (1998). Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry. Gene Therapy, 5(5), 718-722.
Scopus35 WoS29 Europe PMC191998 Wagstaff, M. J. D., Lilley, C. E., Smith, J., Robinson, M. J., Coffin, R. S., & Latchman, D. S. (1998). Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo. Gene Therapy, 5(11), 1566-1570.
Scopus26 WoS22 Europe PMC121996 Wagstaff, M. J. D., Collaço-Moraes, Y., Aspey, B. S., Coffin, R. S., Harrison, M. J. G., Latchman, D. S., & De Belleroche, J. S. (1996). Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Molecular Brain Research, 42(2), 236-244.
Scopus52 WoS54 Europe PMC431995 VYAKARNAM, A., MATEAR, P. M., MARTIN, S. J., & WAGSTAFF, M. (1995). TH1 CELLS SPECIFIC FOR HIV-1 GAG P24 ARE LESS EFFICIENT THAN TH0 CELLS IN SUPPORTING HIV REPLICATION, AND INHIBIT VIRUS-REPLICATION IN TH0 CELLS. IMMUNOLOGY, 86(1), 85-96.
WoS34 Europe PMC251995 LANGLOIS, N. E. I., MILLER, I. D., & MANN, E. M. F. (1995). Adenoid basal carcinoma of the cervix: an unusual cytological appearance. Cytopathology, 6(2), 104-109.
Scopus3 Europe PMC2 -
Books
Year Citation 2011 Raftery, A. T., Delbridge, M. S., & Wagstaff, M. J. D. (2011). Churchill's Pocketbook of Surgery E-Book. Elsevier Health Sciences. -
Book Chapters
Year Citation 2016 Greenwood, J., & Wagstaff, M. (2016). The use of Biodegradable Polyurethane in the Development of Dermal Scaffolds. In S. Cooper, & J. Guan (Eds.), Advances in Polyurethane Biomaterials (pp. 631-662). United Kingdom: Elsevier.
DOI Scopus92010 Wagstaff, M. J. D., Reed, M. W. R., & Caddy, C. M. (2010). Breast reconstruction. In Management of Breast Cancer in Older Women (pp. 213-229). Springer London.
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Conference Papers
Year Citation 2017 Kamran, S. C., Seisen, T., Markt, S. C., Preston, M. A., Frazier, A. L., & Sweeney, C. (2017). Post-orchiectomy adjuvant therapy versus surveillance for stage IS testicular cancer.. In JOURNAL OF CLINICAL ONCOLOGY Vol. 35 (pp. 1 page). LIPPINCOTT WILLIAMS & WILKINS.
DOI2016 Wallace, W. C., Ghafur, O., Khurmi, C., Satya Sainadh, U., Calvert, J. E., Laban, D. E., . . . Tong, X. M. (2016). Percent-level accuracy in measuring strong-field photoionization and laser intensity. In Optics InfoBase Conference Papers (pp. UTh4A.29). OSA.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2020 Co-Supervisor Hypertrophic scar measures relationship to transepidermal water loss, and the effect of generic moisturisers on transepidermal water loss. Doctor of Philosophy Doctorate Part Time Ms Tanja Klotz
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Committee Memberships
Date Role Committee Institution Country 2021 - ongoing Member Fellowship Examination Committee in Plastic and Reconstructive Surgery Royal Australasian College of Surgeons Australia
Connect With Me
External Profiles