Manuela Klingler-Hoffmann

Dr Manuela Klingler-Hoffmann

Senior Research Fellow

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Manuela Klingler-Hoffmann is passionate about making a difference to cancer patients’ lives. She uses proteomics to analyse patient-derived samples with the long-term goal to assists clinicians in their therapy decisions. She is an experienced cell biologist and biochemist with a background in biophysics and the recipient of multiple fellowships and awards, such as the 2020 Winnovation award in the Science category.
She is leading a small and dedicated team working on translational research projects and develops disruptive laboratory solutions for personalised medicine and novel sample preparation for mass spectrometry.
After finishing her PhD in 1999 at the German Cancer Research Centre in Heidelberg, Germany, she has been awarded a prestigious DFG (German Research Foundation) fellowship to work at Monash University in Melbourne. After her time at Monash University, she has been working part time in several laboratories around the world and had several career interruptions. In 2016 she was the recipient of a Barbara Kidman Fellowship, which aims to enhance and promote the career of female academics. She has co-supervised more than a dozen Honour’s students and PhD students and numerous vacation scholarship students; with multiple winning internal and external awards, such as the University medal for best the PhD thesis in Biological Sciences.

Date Institution name Country Title
Saarland University Germany PhD

Date Title Institution Country
Dip Ed University of Adelaide Australia

Year Citation
2026 Scanlan, J., Mittal, P., Lokman, N. A., Oehler, M. K., Hoffmann, P., & Klingler-Hoffmann, M. (2026). Toward Proteomic-Based Prediction of Ex Vivo Platinum Sensitivity in Ovarian Cancer Ascitic Cellular Aggregates: A Pilot Study.. Journal of proteome research, 25(2), 828-841.
DOI WoS1
2026 Scanlan, J., Mittal, P., Oehler, M. K., Hoffmann, P., & Hoffmann, M. K. (2026). Proteomic Studies That Predict Patients’ Responses to High-Grade Serous Ovarian Cancer Treatments: A Systematic Review. Journal of Proteome Research, 25(2), 1126-1138.
DOI Scopus1 WoS1 Europe PMC1
2026 Lau, D., Mittal, P., Scanlan, J., Donnellan, L., Klingler-Hoffmann, M., & Hoffmann, P. (2026). Tissue-resolved proteomic characterization of oat grains guided by metabolite MALDI mass spectrometry imaging. Analytical and Bioanalytical Chemistry, 14 pages.
DOI
2026 Scanlan, J., Mittal, P., Washington, J., Young, C., Antoniou, M., Kochetkova, M., . . . Klingler-Hoffmann, M. (2026). Proteomic analysis of malignant ascites and its impact on ovarian cancer spheroids.. Clinical proteomics.
DOI
2025 Lee, J. H., Sumer-Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567(120108), 120108.
DOI Scopus2 WoS2 Europe PMC1
2025 Lau, D., Donnellan, L., Briggs, M., Klingler Hoffmann, M., & Hoffmann, P. (2025). MALDI Mass spectrometry imaging of metabolites in cereal grains and legumes: repurposing for industrial applications. Food Reviews International, 41(4), 1200-1221.
DOI Scopus5 WoS5
2025 Palethorpe, H. M., Shard, C., Scheer, K. G., Ryan, C. P., Fouladzadeh, A., Wenholz, D., . . . Gomez, G. A. (2025). An Optimized Explant Organoid Method for Preclinical Brain Tumor Research. NEURO-ONCOLOGY, 27(Supplement_5), v167.
DOI
2025 Dharmayanti, C., Clulow, A. J., Hussain, M. S., Gillam, T. A., Klingler Hoffmann, M., Albrecht, H., & Blencowe, A. (2025). Influence of pendant pyridyl regioisomers on the pH-responsive behaviour of polymer-homopeptide copolymers and micelles. European Polymer Journal, 234(113931), 1-11.
DOI Scopus2 WoS2
2025 Noye, T. M., Mittal, P., Price, Z. K., Fewster, A., Williams, G., Pukala, T. L., . . . Ricciardelli, C. (2025). Identification of Proteins Associated with Ovarian Cancer Chemotherapy Resistance Using MALDI-MSI. International Journal of Molecular Sciences, 26(12), 5893.
DOI Scopus1 WoS1
2025 Seidel, J. D., Young, C., Klingler Hoffmann, M., Condina, M. R., Shah, A., Ramarathinam, S., . . . Hoffmann, P. (2025). Analytical methods for in-depth characterisation of cell culture bioreactors: A case study. Journal of Chromatography Open, 8(100248), 1-13.
DOI
2025 Ngai, Y. T., Young, C., Parkinson-Lawrence, E. J., Wimmer-Kleikamp, S., Mittal, P., Beard, H., . . . Hoffmann, P. (2025). Defining lung pathogenesis in a murine model of mucopolysaccharidosis Type I by proteomic analysis. Molecular Genetics and Metabolism, 146(1-2), 109231.
DOI Scopus1 WoS1
2024 Dilmetz, B. A., Desire, C. T., Meneses, J., Klingler-Hoffmann, M., Young, C., & Hoffmann, P. (2024). Impact of propagation time on yeast physiology during bottle conditioning of beer on an industrial scale. Food Chemistry, 435, 1-9.
DOI Scopus5 WoS4 Europe PMC2
2024 Sukjoi, W., Young, C., Acland, M., Siritutsoontorn, S., Roytrakul, S., Klingler Hoffmann, M., . . . Jitrapakdee, S. (2024). Proteomic analysis of holocarboxylase synthetase deficient-MDA-MB-231 breast cancer cells revealed the biochemical changes associated with cell death, impaired growth signaling, and metabolism. Frontiers in Molecular Biosciences, 10, 1-16.
DOI Scopus1 WoS1 Europe PMC1
2024 Li, C. M. Y., Briggs, M. T., Lee, Y. -R., Tin, T., Young, C., Pierides, J., . . . Fenix, K. (2024). Use of tryptic peptide MALDI mass spectrometry imaging to identify the spatial proteomic landscape of colorectal cancer liver metastases.. Clin Exp Med, 24(1), 53.
DOI Scopus14 WoS14 Europe PMC13
2024 Ngai, Y. T., Briggs, M. T., Mittal, P., Young, C., Parkinson-Lawrence, E., Klingler-Hoffmann, M., . . . Hoffmann, P. (2024). Mass spectrometry imaging protocol for spatial mapping of lipids, N-glycans and peptides in murine lung tissue. Rapid Communications in Mass Spectrometry, 38(9), e9721.
DOI Scopus6 WoS7 Europe PMC4
2024 Moxon, J. V., Pretorius, C., Trollope, A. F., Mittal, P., Klingler-Hoffmann, M., Hoffmann, P., & Golledge, J. (2024). A systematic review and in silico analysis of studies investigating the ischaemic penumbra proteome in animal models of experimental stroke. Journal of Cerebral Blood Flow and Metabolism, 44(10), 1709-1722.
DOI Scopus7 WoS7 Europe PMC6
2024 Dharmayanti, C., Clulow, A. J., Gillam, T. A., Klingler Hoffmann, M., Albrecht, H., & Blencowe, A. (2024). Position matters: pyridine regioisomers influence secondary structure and micelle morphology in polymer-homopolypeptide micelles. Biomacromolecules, 25(7), 4095-4109.
DOI Scopus6 WoS6 Europe PMC2
2024 Dilmetz, B. A., Brar, G., Desire, C. T., Meneses, J., Klingler Hoffmann, M., Young, C., & Hoffmann, P. (2024). Performance of different Saccharomyces strains on secondary fermentation during the production of beer. Foods, 13(16, article no. 2593), 1-17.
DOI Scopus5 WoS4
2024 Seidel, J. D., Condina, M. R., Klingler Hoffmann, M., Young, C., Donnellan, L., Kyngdon, C., & Hoffmann, P. (2024). Development of an optimized LC-MS workflow for host cell protein characterization to support upstream process development. Journal of Proteome Research, 24(1), 234-243.
DOI Scopus2 WoS2 Europe PMC1
2023 Arentz, G., Mittal, P., Klingler-Hoffmann, M., Condina, M. R., Ricciardelli, C., Lokman, N. A., . . . Hoffmann, P. (2023). Label-Free Quantification Mass Spectrometry Identifies Protein Markers of Chemotherapy Response in High-Grade Serous Ovarian Cancer. Cancers, 15(7), 14 pages.
DOI Scopus7 WoS8 Europe PMC7
2023 Dilmetz, B. A., Desire, C. T., Donnellan, L., Meneses, J., Klingler Hoffmann, M., & Young, C. (2023). Assessment of yeast physiology during industrial-scale brewing practices using the redox-sensitive dye resazurin. Yeast, 40(5-6), 171-181.
DOI Scopus3 WoS3 Europe PMC2
2023 Sebastian, S., Hoffmann, M. K., Howard, D., Young, C., Washington, J., Unterweger, H., . . . Kempson, I. (2023). Kinetic effects of transferrin-conjugated gold nanoparticles on the antioxidant glutathione-thioredoxin pathway. Antioxidants, 12(8, article no. 1617), 1-21.
DOI Scopus8 WoS8 Europe PMC8
2022 Khetan, R., Dharmayanti, C., Gillam, T. A., Kübler, E., Klingler-Hoffmann, M., Ricciardelli, C., . . . Albrecht, H. (2022). Using GPCRs as Molecular Beacons to Target Ovarian Cancer with Nanomedicines. Cancers, 14(10), 1-32.
DOI Scopus15 WoS15 Europe PMC15
2022 Acland, M., Lokman, N. A., Young, C., Anderson, D., Condina, M., Desire, C., . . . Klingler-Hoffmann, M. (2022). Chemoresistant Cancer Cell Lines Are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations. Cancers, 14(11), 1-24.
DOI Scopus8 WoS8 Europe PMC10
2022 Acland, M., Mittal, P., Arentz, G., Whitehead, F., Hoffmann, P., Klingler Hoffmann, M., & Oehler, M. K. (2022). A protocol for the acquisition of comprehensive proteomics data from single cases using formalin-fixed paraffin embedded sections. Methods and Protocols, 5(4, article no. 57), 1-17.
DOI Scopus3 WoS3 Europe PMC3
2021 Mittal, P., Briggs, M., Klingler-Hoffmann, M., Kaur, G., Packer, N. H., Oehler, M. K., & Hoffmann, P. (2021). Altered N-linked glycosylation in endometrial cancer. Analytical and Bioanalytical Chemistry, 413(10), 2721-2733.
DOI Scopus24 WoS24 Europe PMC25
2021 Dharmayanti, C., Gillam, T. A., Klingler Hoffmann, M., Albrecht, H., & Blencowe, A. (2021). Strategies for the development of pH-responsive synthetic polypeptides and polymer-peptide hybrids: recent advancements. Polymers, 13(4), 1-16.
DOI Scopus58 WoS46 Europe PMC29
2021 Mittal, P., Condina, M. R., Klingler-Hoffmann, M., Kaur, G., Oehler, M. K., Sieber, O. M., . . . Hoffmann, P. (2021). Cancer tissue classification using supervised machine learning applied to maldi mass spectrometry imaging. Cancers, 13(21), 16 pages.
DOI Scopus35 WoS28 Europe PMC20
2021 Dilmetz, B. A., Lee, Y. R., Condina, M. R., Briggs, M., Young, C., Desire, C. T., . . . Hoffmann, P. (2021). Novel technical developments in mass spectrometry imaging in 2020: A mini review. Analytical Science Advances, 2(3-4), 225-237.
DOI Scopus30 WoS29 Europe PMC30
2020 Boyle, S. T., Mittal, P., Kaur, G., Hoffmann, P., Samuel, M. S., & Klingler-Hoffmann, M. (2020). Uncovering tumor−stroma inter-relationships using MALDI Mass spectrometry imaging. Journal of Proteome Research, 19(10), 4093-4103.
DOI Scopus16 WoS16 Europe PMC15
2020 Weiland, F., Lokman, N. A., Klingler-Hoffmann, M., Jobling, T., Stephens, A. N., Sundfeldt, K., . . . Oehler, M. K. (2020). Ovarian Blood Sampling Identifies Junction Plakoglobin as a Novel Biomarker of Early Ovarian Cancer. Frontiers in Oncology, 10(1767), 1-10.
DOI Scopus11 WoS11 Europe PMC13
2020 Acland, M., Arentz, G., Mussared, M., Whitehead, F., Hoffmann, P., Klingler Hoffmann, M., & Oehler, M. K. (2020). Proteomic analysis of pre-invasive serous lesions of the endometrium and fallopian tube reveals their metastatic potential. Frontiers in Oncology, 10(article no. 523989), 1-12.
DOI Scopus5 WoS5 Europe PMC5
2019 Briggs, M. T., Condina, M. R., Klingler-Hoffmann, M., Arentz, G., Everest-Dass, A. V., Kaur, G., . . . Hoffmann, P. (2019). Translating N-Glycan Analytical Applications into Clinical Strategies for Ovarian Cancer. Proteomics - Clinical Applications, 13(3), 1-5.
DOI Scopus23 WoS19 Europe PMC16
2019 Mittal, P., Price, Z. K., Lokman, N. A., Ricciardelli, C., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for monitoring of drug response in primary cancer spheroids. Proteomics, 19(21 - 22), e1900146-1-e1900146-4.
DOI Scopus24 WoS21 Europe PMC18
2019 Klingler-Hoffmann, M., Mittal, P., & Hoffmann, P. (2019). The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers.. Proteomics, 19(21-22), e1800483.
DOI Scopus17 WoS12 Europe PMC10
2019 Condina, M. R., Mittal, P., Briggs, M. T., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Egg white as a quality control in matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI).. Analytical chemistry, 91(23), 14846-14853.
DOI Scopus13 WoS14 Europe PMC12
2018 Chong, C. -E., Venugopal, P., Stokes, P., Lee, Y., Brautigan, P., Yeung, D., . . . Scott, H. (2018). Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes. Leukemia, 32(1), 194-202.
DOI Scopus57 WoS54 Europe PMC54
2018 Acland, M., Mittal, P., Lokman, N., Klingler-Hoffmann, M., Oehler, M., & Hoffmann, P. (2018). Mass spectrometry analyses of multicellular tumor spheroids. Proteomics Clinical Applications, 12(3), 1700124-1-1700124-13.
DOI Scopus26 WoS23 Europe PMC24
2017 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Kaur, G., Anderson, L., . . . Oehler, M. (2017). Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.. Biochim Biophys Acta, 1865(7), 846-857.
DOI Scopus26 WoS26 Europe PMC23
2017 Amare, A., Schubert, K., Klingler-Hoffmann, M., Cohen-Woods, S., & Baune, B. (2017). The genetic overlap between mood disorders and cardiometabolic diseases: A systematic review of genome wide and candidate gene studies. Translational Psychiatry, 7(1), 1-12.
DOI Scopus305 WoS265 Europe PMC268
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Zhang, C., Kaur, G., Oehler, M., & Hoffmann, P. (2016). Proteomics of endometrial cancer diagnosis, treatment, and prognosis. Proteomics - Clinical Applications, 10(3), 217-229.
DOI Scopus25 WoS23 Europe PMC21
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Lokman, N., Zhang, C., . . . Hoffmann, P. (2016). Lymph node metastasis of primary endometrial cancers: associated proteins revealed by MALDI imaging. Proteomics, 16(11-12), 1793-1801.
DOI Scopus29 WoS29 Europe PMC30
2016 Barnett, C. P., Nataren, N. J., Klingler-Hoffmann, M., Schwarz, Q., Chong, C. E., Lee, Y. K., . . . Scott, H. S. (2016). Ectrodactyly and lethal pulmonary acinar dysplasia associated with homozygous FGFR2 mutations identified by exome sequencing. Human Mutation, 37(9), 955-963.
DOI Scopus33 WoS24 Europe PMC26
2016 Zhang, C., Arentz, G., Winderbaum, L., Lokman, N., Klingler-Hoffmann, M., Mittal, P., . . . Hoffmann, P. (2016). MALDI mass spectrometry imaging reveals decreased CK5 levels in vulvar squamous cell carcinomas compared to the precursor lesion differentiated vulvar intraepithelial neoplasia. International Journal of Molecular Sciences, 17(7), 1088-1-1088-12.
DOI Scopus14 WoS11 Europe PMC13
2016 Weiland, F., Arentz, G., Klingler-Hoffmann, M., McCarthy, P., Lokman, N., Kaur, G., . . . Hoffmann, P. (2016). A novel IEF peptide fractionation method reveals a detailed profile of N-terminal Acetylation in chemotherapy-responsive and -resistant ovarian cancer cells. Journal of Proteome Research, 15(11), 4073-4081.
DOI Scopus8 WoS7 Europe PMC7
2016 Barnett, C. P., Nataren, N. J., Klingler-Hoffmann, M., Schwarz, Q., Chong, C. E., Lee, Y. K., . . . Scott, H. S. (2016). Cover Image, Volume 37, Issue 9. Human Mutation, 37(9), i.
DOI
2015 Hahn, C., Brautigan, P., Chong, C., Janssan, A., Venugopal, P., Lee, Y., . . . Scott, H. (2015). Characterisation of a compound in-cis GATA2 germline mutation in a pedigree presenting with myelodysplastic syndrome/acute myeloid leukemia with concurrent thrombocytopenia. Leukemia, 29(8), 1795-1797.
DOI Scopus9 WoS10 Europe PMC11
2015 Turvey, M., Klingler-Hoffmann, M., Hoffmann, P., & McColl, S. (2015). p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration. Immunology and Cell Biology, 93(8), 735-743.
DOI Scopus7 WoS7 Europe PMC8
2014 Humphries, J., Penno, M., Weiland, F., Klingler-Hoffmann, M., Zuber, A., Boussioutas, A., . . . Hoffmann, P. (2014). Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer. Biochimica et Biophysica Acta - Proteins and Proteomics, 1844(5), 1051-1058.
DOI Scopus54 WoS52 Europe PMC43
2013 Sciacca, B., François, A., Klingler-Hoffmann, M., Brazzatti, J., Penno, M., Hoffmann, P., & Monro, T. (2013). Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications. Nanomedicine: Nanotechnology, Biology & Medicine, 9(4), 550-557.
DOI Scopus54 WoS38 Europe PMC16
2013 Niu, M., Klingler-Hoffmann, M., Brazzatti, J., Forbes, B., Akekawatchai, C., Hoffmann, P., & McColl, S. (2013). Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line. Proteome Science, 11(1), 1-12.
DOI Scopus7 WoS3 Europe PMC4
2012 Penno, M., Klingler-Hoffmann, M., Brazzatti, J., Boussioutas, A., Putoczki, T., Ernst, M., & Hoffmann, P. (2012). 2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer. Journal of Proteomics, 77, 40-58.
DOI Scopus27 WoS26 Europe PMC22
2012 Brazzatti, J., Klingler-Hoffmann, M., Haylock-Jacobs, S., Harata-Lee, Y., Niu, M., Higgins, M., . . . McColl, S. (2012). Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis. Oncogene, 31(18), 2350-2361.
DOI Scopus48 WoS46 Europe PMC46
2011 Haylock-Jacobs, S., Comerford, I., Bunting, M., Kara, E., Townley, S., Klingler-Hoffmann, M., . . . McColl, S. (2011). PI3Kδ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation. Journal of Autoimmunity, 36(3-4), 278-287.
DOI Scopus76 WoS75 Europe PMC70
2010 Condina, M., Klingler-Hoffmann, M., & Hoffmann, P. (2010). Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS. Current Protocols in Protein Science, Suppl 2(13.11), 1-26.
DOI Scopus6 Europe PMC3
2010 Condina, M., Gustafsson, O., Klingler-Hoffmann, M., Bagley, C., McColl, S., & Hoffmann, P. (2010). EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation. Proteomics, 10(13), 2516-2530.
DOI Scopus8 WoS8 Europe PMC7
2005 Klingler-Hoffmann, M., Barth, H., Richards, J., Konig, N., & Kinzel, V. (2005). Downregulation of protein phosphatase 2A activity in HeLa cells at the G2-mitosis transition and unscheduled reactivation induced by 12-O-tetradecanoyl phorbol-13-acetate (TPA). European Journal of Cell Biology, 84(8), 719-732.
DOI Scopus8 WoS8 Europe PMC7
2004 Bukczynska, P., Klingler-Hoffmann, M., Mitchelhill, K., Lam, M., Cicomancini, M., Tonks, N., . . . Tiganis, T. (2004). The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis. Biochemical Journal, 380(3), 939-949.
DOI Scopus18 WoS17 Europe PMC15
2003 Klingler-Hoffmann, M., Bukczynska, P., & Tiganis, T. (2003). Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells. International Journal of Cancer, 105(3), 331-339.
DOI Scopus40 WoS39 Europe PMC32
2003 Galic, S., Klingler-Hoffmann, M., Fodero-Tavoletti, M., Puryer, M., Meng, T., Tonks, N., & Tiganis, T. (2003). Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Molecular and Cellular Biology, 23(6), 2096-2108.
DOI Scopus163 WoS146 Europe PMC131
2001 Klingler-Hoffmann, M., Fodero-Tavoletti, M., Mishima, K., Narita, Y., Cavenee, W., Furnari, F., . . . Tiganis, T. (2001). The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. Journal of Biological Chemistry, 276(49), 46313-46318.
DOI Scopus70 WoS64 Europe PMC58
1999 Barth, H., Klingler, M., Aktories, K., & Kinzel, V. (1999). <i>Clostridium botulinum</i> C2 toxin delays entry into mitosis and activation of p34<i><SUP>cdc2</SUP></i> kinase and cdc25-C phosphatase in HeLa cells. INFECTION AND IMMUNITY, 67(10), 5083-5090.
DOI WoS18 Europe PMC15
1996 Klingler, M. (1996). Radiation with 1 Gy prevents the activation of the mitotic inducers mitosis-promoting factor (MPF) and cdc25-C in HeLa cells. Cancer Research.

Year Citation
2017 Arentz, G., Mittal, P., Zhang, C., Ho, Y., Briggs, M., Winderbaum, L., . . . Hoffmann, P. (2017). Applications of mass spectrometry imaging to cancer. In R. Drake (Ed.), Advances in Cancer Research (Vol. 134, pp. 27-66). USA: Academic Press.
DOI Scopus67 WoS57 Europe PMC47
2010 Condina, M., Klingler-Hoffmann, M., & Hoffmann, P. (2010). Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS.. In Unknown Book (Vol. Chapter 13).
Scopus1

Year Citation
2014 Hoffmann, P., Gustafsson, J. O. R., Zhang, C., Mitall, P., Klingler-Hoffmann, M., & Oehler, M. K. (2014). PEPTIDE IMAGING MASS SPECTROMETRY ON FORMALIN FIXED PARAFFIN EMBEDDED TISSUE IN GYNAECOLOGICAL CANCER. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. LIPPINCOTT WILLIAMS & WILKINS.

Year Citation
2026 Scanlan, J., Mittal, P., Washington, J., Young, C., Oehler, M., Hoffmann, P., & Klingler-Hoffmann, M. (2026). Ascites-Driven Modulation of Cell Phenotypes and Proteomes: Implications for Cancer Progression.
DOI

  • Enabling personalised medicine for patients with ovarian cancer, Tour de Cure Ltd, 01/11/2021 - 31/12/2022

Courses I teach

  • BIOL 1056 Biomedical Research Training (2024)

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor Shining a light on the dark proteome of ovarian cancer Doctor of Philosophy Doctorate Full Time Ms Paula González Menéndez
2023 Principal Supervisor Towards personalised treatment of Ovarian Cancer Doctor of Philosophy Doctorate Full Time Mr Jack Scanlan
2022 Co-Supervisor Process analytical technologies for the development and monitoring of cell culture processes in biopharmaceutical production Doctor of Philosophy Doctorate Full Time Mr Janik Seidel
2021 Co-Supervisor Functional Analysis and Quantification of Biopharmaceuticals in Tissues by Mass Spectrometry Imaging Doctor of Philosophy Doctorate Part Time Ms Sammi Ngai

Date Role Research Topic Program Degree Type Student Load Student Name
2021 - 2024 Co-Supervisor Linking the intracellular journey of gold nanoparticles to protein expression changes in prostate cancer cells Doctor of Philosophy Doctorate Part Time Mrs Sonia Sebastian
2021 - 2025 Co-Supervisor Maximising yeast health during the industrial brewing process Doctor of Philosophy Doctorate Part Time Miss Brooke Dilmetz
2020 - 2024 Co-Supervisor Development of pH-responsive polymer-homopolypeptide micelles for drug delivery Doctor of Philosophy Doctorate Part Time Miss I Gusti Ayu Agung Cintya Dharmayanti
2016 - 2023 Principal Supervisor Characterisation of Ovarian Cancer Development, Progression and Treatment Resistance Through Mass Spectrometry Analysis Doctor of Philosophy Doctorate Full Time Mr Mitchell Aidan Acland
2014 - 2017 External Supervisor Molecular Characterization of Metastatic Endometrial Cancer by Mass Spectrometry Doctor of Philosophy Doctorate Full Time Ms Parul Mittal
2013 - 2016 Co-Supervisor Identification and Characterisation of Genetic Lesions that Predispose to and Gene Expression Patterns that Contribute to Myeloid Malignancies Doctor of Philosophy Doctorate Full Time Ms Parvathy Venugopal
2011 - 2015 Co-Supervisor The role and regulation of the p84 adaptor subunit in phosphatidylinositol 3-kinase gamma lipid-kinase signalling and the control of PI3Kgamma-dependent cell migration Doctor of Philosophy Doctorate Full Time Ms Michelle Elizabeth Turvey
2010 - 2012 Co-Supervisor Investigation of P13Ky Signalimg Downstream of IGF-1R1CXCR4 Transactivation in Metastatic MDA-MB 231 Breast Cancer Cells Doctor of Philosophy Doctorate Full Time Ms Meizhi Niu
2007 - 2011 Co-Supervisor The Differential Roles of p101 and p84, the Regulatory Subunits of Phosphoinositide 3-kinase Gamma, in Cell Migration Doctor of Philosophy Doctorate Full Time Miss Julie Brazzatti
2006 - 2010 Co-Supervisor The Role of Class IA PI3K? in Experimental Autoimmune Encephalomyelitis Doctor of Philosophy Doctorate Full Time Mrs Sarah Haylock-Jacobs

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