Parul Mittal

Dr Parul Mittal

Research Associate

School of Pharmacy and Biomedical Science

College of Health

Available For Media Comment.

Parul Mittal is a Research Associate in the Mass spectrometry & Proteomics group, UniSA Clinical & Health Sciences. She obtained her PhD from the University of Adelaide in 2018 for her research in endometrial cancer and received a Dean’s Commendation for Doctoral Research Excellence.
She is a mass spectrometry specialist and has been engaged in many collaborative projects with universities, hospitals, and research centres across projects such as the analysis of cancer samples, organoids, spheroids, as well as the development of new data analysis methods.
Parul joined the University in 2020, after working as the Service and Facility officer at the Adelaide Proteomics Centre at the University of Adelaide for two years. There she was a vital part of a small and dedicated team operating the fee-for-service facility.

Year Citation
2025 Ngai, Y. T., Lau, D., Mittal, P., & Hoffmann, P. (2025). Mini Review: Highlight of Recent Advances and Applications of MALDI Mass Spectrometry Imaging in 2024. Analytical Science Advances, 6(1), 11 pages.
DOI Scopus5 WoS4 Europe PMC4
2025 Lee, J. H., Sumer Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567(120108), 1-8.
DOI Scopus1 WoS1 Europe PMC1
2025 Palethorpe, H., Shard, C., Scheer, K., Ryan, C., Fouladzadeh, A., Wenholz, D., . . . Gomez, G. (2025). An optimized explant organoid method for preclinical brain tumour research. NEURO-ONCOLOGY, 27(Supplement_5), v167.
DOI
2025 Noye, T. M., Mittal, P., Price, Z. K., Fewster, A., Williams, G., Pukala, T. L., . . . Ricciardelli, C. (2025). Identification of Proteins Associated with Ovarian Cancer Chemotherapy Resistance Using MALDI-MSI. International Journal of Molecular Sciences, 26(12), 5893.
DOI
2025 Ngai, Y. T., Young, C., Parkinson-Lawrence, E. J., Wimmer-Kleikamp, S., Mittal, P., Beard, H., . . . Hoffmann, P. (2025). Defining lung pathogenesis in a murine model of mucopolysaccharidosis Type I by proteomic analysis. Molecular Genetics and Metabolism, 146(1-2), 109231.
DOI
2024 Ngai, Y. T., Briggs, M. T., Mittal, P., Young, C., Parkinson-Lawrence, E., Klingler-Hoffmann, M., . . . Hoffmann, P. (2024). Mass spectrometry imaging protocol for spatial mapping of lipids, N-glycans and peptides in murine lung tissue. Rapid Communications in Mass Spectrometry, 38(9), e9721.
DOI Scopus6 WoS4 Europe PMC3
2024 Moxon, J. V., Pretorius, C., Trollope, A. F., Mittal, P., Klingler-Hoffmann, M., Hoffmann, P., & Golledge, J. (2024). A systematic review and in silico analysis of studies investigating the ischaemic penumbra proteome in animal models of experimental stroke. Journal of Cerebral Blood Flow and Metabolism, 44(10), 1709-1722.
DOI Scopus2 WoS3 Europe PMC2
2023 Arentz, G., Mittal, P., Klingler-Hoffmann, M., Condina, M. R., Ricciardelli, C., Lokman, N. A., . . . Hoffmann, P. (2023). Label-Free Quantification Mass Spectrometry Identifies Protein Markers of Chemotherapy Response in High-Grade Serous Ovarian Cancer. Cancers, 15(7), 14 pages.
DOI Scopus4 WoS5 Europe PMC4
2023 Sanyal, S. K., Pukala, T., Mittal, P., Reith, F., Brugger, J., Etschmann, B., & Shuster, J. (2023). From biomolecules to biogeochemistry: Exploring the interaction of an indigenous bacterium with gold. Chemosphere, 339, 139657-1-139657-12.
DOI Scopus1
2023 Kumarasamy, G., Ismail, M. N., Tuan Sharif, S. E., Desire, C., Mittal, P., Hoffmann, P., & Kaur, G. (2023). Protein profiling in human papillomavirus-associated cervical carcinogenesis: cornulin as a biomarker for disease progression. Current Issues in Molecular Biology, 45(4), 3603-3627.
DOI Scopus4 WoS3 Europe PMC3
2022 Lin, V. J. T., Hu, J., Zolekar, A., Salick, M. R., Mittal, P., Bird, J. T., . . . Wang, Y. C. (2022). Deficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids. Cell Death & Disease, 13(3, article no. 262), 1-13.
DOI Scopus13 WoS11 Europe PMC9
2022 Acland, M., Mittal, P., Arentz, G., Whitehead, F., Hoffmann, P., Klingler Hoffmann, M., & Oehler, M. K. (2022). A protocol for the acquisition of comprehensive proteomics data from single cases using formalin-fixed paraffin embedded sections. Methods and Protocols, 5(4, article no. 57), 1-17.
DOI Scopus3 WoS3 Europe PMC3
2021 Mittal, P., Briggs, M., Klingler-Hoffmann, M., Kaur, G., Packer, N. H., Oehler, M. K., & Hoffmann, P. (2021). Altered N-linked glycosylation in endometrial cancer. Analytical and Bioanalytical Chemistry, 413(10), 2721-2733.
DOI Scopus20 WoS20 Europe PMC20
2021 Enot, M. M., Weiland, F., Mittal, P., Hoffmann, P., Sillero-Mahinay, M., & Pukala, T. (2021). Differential proteome analysis of the leaves of lead hyperaccumulator, Rhoeo discolor (L. Her.) Hance. Journal of Mass Spectrometry, 56(4), e4689-1-e4689-11.
DOI Scopus10 WoS6 Europe PMC3
2021 Mittal, P., Condina, M. R., Klingler-Hoffmann, M., Kaur, G., Oehler, M. K., Sieber, O. M., . . . Hoffmann, P. (2021). Cancer tissue classification using supervised machine learning applied to maldi mass spectrometry imaging. Cancers, 13(21), 16 pages.
DOI Scopus29 WoS23 Europe PMC15
2020 Wang, C. R., Bubner, E. R., Jovcevski, B., Mittal, P., & Pukala, T. L. (2020). Interrogating the higher order structures of snake venom proteins using an integrated mass spectrometric approach.. J Proteomics, 216, 103680.
DOI Scopus21 WoS20 Europe PMC19
2020 Salman Sajid, M., Jovcevski, B., Mittal, P., Fatima, B., Hussain, D., Jabeen, F., . . . Najam-ul-Haq, M. (2020). Glycosylation heterogeneity and low abundant serum glycoproteins MS analysis by boronic acid immobilized Fe<inf>3</inf>O<inf>4</inf>@1,2-Epoxy-5-Hexene/DVB magnetic core shell nanoparticles. Microchemical Journal, 159, 8 pages.
DOI Scopus7 WoS8
2020 Boyle, S. T., Mittal, P., Kaur, G., Hoffmann, P., Samuel, M. S., & Klingler-Hoffmann, M. (2020). Uncovering tumor−stroma inter-relationships using MALDI Mass spectrometry imaging. Journal of Proteome Research, 19(10), 4093-4103.
DOI Scopus16 WoS15 Europe PMC13
2019 Briggs, M. T., Condina, M. R., Ho, Y. Y., Everest-Dass, A. V., Mittal, P., Kaur, G., . . . Hoffmann, P. (2019). MALDI mass spectrometry imaging of early- and late-stage serous ovarian cancer tissue reveals stage-specific N-glycans. Proteomics, 19(21-22), 1800482-1-1800482-11.
DOI Scopus52 WoS46 Europe PMC41
2019 Mittal, P., Price, Z. K., Lokman, N. A., Ricciardelli, C., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for monitoring of drug response in primary cancer spheroids. Proteomics, 19(21 - 22), e1900146-1-e1900146-4.
DOI Scopus22 WoS20 Europe PMC16
2019 Klingler-Hoffmann, M., Mittal, P., & Hoffmann, P. (2019). The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers.. Proteomics, 19(21-22), e1800483.
DOI Scopus16 WoS12 Europe PMC9
2019 Condina, M. R., Mittal, P., Briggs, M. T., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Egg white as a quality control in matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI).. Analytical chemistry, 91(23), 14846-14853.
DOI Scopus13 WoS14 Europe PMC10
2019 Guo, Q., Ng, P. Q., Shi, S., Fan, D., Li, J., Zhao, J., . . . Searle, I. R. (2019). Arabidopsis TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth. PLoS ONE, 14(11), 1-26.
DOI Scopus23 WoS22 Europe PMC21
2018 Acland, M., Mittal, P., Lokman, N., Klingler-Hoffmann, M., Oehler, M., & Hoffmann, P. (2018). Mass spectrometry analyses of multicellular tumor spheroids. Proteomics Clinical Applications, 12(3), 1700124-1-1700124-13.
DOI Scopus23 WoS21 Europe PMC19
2017 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Kaur, G., Anderson, L., . . . Oehler, M. (2017). Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.. Biochim Biophys Acta, 1865(7), 846-857.
DOI Scopus25 WoS25 Europe PMC22
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Zhang, C., Kaur, G., Oehler, M., & Hoffmann, P. (2016). Proteomics of endometrial cancer diagnosis, treatment, and prognosis. Proteomics - Clinical Applications, 10(3), 217-229.
DOI Scopus24 WoS22 Europe PMC18
2016 Winderbaum, L., Koch, I., Mittal, P., & Hoffmann, P. (2016). Classification of MALDI-MS imaging data of tissue microarrays using canonical correlation analysis based variable selection. Proteomics, 16(11-12), 1731-1735.
DOI Scopus9 WoS9 Europe PMC7
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Lokman, N., Zhang, C., . . . Hoffmann, P. (2016). Lymph node metastasis of primary endometrial cancers: associated proteins revealed by MALDI imaging. Proteomics, 16(11-12), 1793-1801.
DOI Scopus27 WoS27 Europe PMC24
2016 Zhang, C., Arentz, G., Winderbaum, L., Lokman, N., Klingler-Hoffmann, M., Mittal, P., . . . Hoffmann, P. (2016). MALDI mass spectrometry imaging reveals decreased CK5 levels in vulvar squamous cell carcinomas compared to the precursor lesion differentiated vulvar intraepithelial neoplasia. International Journal of Molecular Sciences, 17(7), 1088-1-1088-12.
DOI Scopus12 WoS9 Europe PMC11

Year Citation
2025 Scheer, K., Yeo, E., Shard, C., Lenin, S., Ormsby, R., Skarne, N., . . . Gomez, G. (2025). Growth rates of patient-derived tumor organoids reflect glioblastoma patients' heterogeneity in survival. In NEURO-ONCOLOGY Vol. 27 (pp. v479). OXFORD UNIV PRESS INC.
DOI

Year Citation
2024 Palethorpe, H. M., Shard, C., Scheer, K. G., Ryan, C. P., Fouladzadeh, A., Wenholz, D., . . . Gomez, G. A. (2024). An Optimized Explant Organoid Method for Preclinical Brain Tumor Research.
DOI
2018 Guo, Q., Ng, P. Q., Shi, S., Fan, D., Li, J., Wang, H., . . . Searle, I. R. (2018). <i>Arabidopsis</i> TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth.
DOI

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