Dr Luke Selth

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• Appointments

  Date	Position	Institution name
  2015	Senior Research Fellow	University of Adelaide
  2009 - 2014	Research Fellow	University of Adelaide
  2005 - 2009	Post-doctoral Fellow	Cancer Research UK London Research Institute

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2016	Fellowship	Endeavour Research Fellowship	—	—	—
  2015	Research Award	Australian Society for Medical Research Leading Light Award (finalist)	—	—	—
  2013	Award	South Australian Young Tall Poppy Science Award	—	—	—
  2012	Award	Prostate Cancer Foundation Young Investigator Award	—	—	—
  2011	Award	Millennium Sciences Award (Lorne Genome Conference)	—	—	—
  2011	Award	Prostate Cancer Foundation of Australia Young Investigator Award	—	—	—
  2010	Award	International Conference Award	University of Adelaide Faculty of Health Sciences	—	—
  2005	Fellowship	European Molecular Biology Organisation (EMBO) Long-Term Fellowship	—	—	—

• Education

  Date	Institution name	Country	Title
  2005	University of Adelaide	Australia	PhD
  2000	Flinders University	Australia	B. Biotechnology (Honours)

• Research Interests

  Cancer Biology and Clinical Oncology Cancer Cell Biology Cancer Therapy

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• Journals

  Year	Citation
  2019	Das, R., Feng, F. Y., & Selth, L. A. (2019). Long non-coding RNAs in prostate cancer: biological and clinical implications. Molecular and Cellular Endocrinology, 480, 142-152. DOI Scopus3 WoS3 Europe PMC1
  2019	MacFawn, I., Wilson, H., Selth, L., Leighton, I., Serebriiskii, I., Bleackley, R., . . . Frisch, S. (2019). Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers. Molecular Immunology, 105, 137-149. DOI Scopus3 WoS3 Europe PMC1
  2019	Watt, M., Clark, A., Selth, L., Haynes, V., Lister, N., Rebello, R., . . . Taylor, R. (2019). Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer. Science Translational Medicine, 11(478), 1-12. DOI Scopus10 WoS8 Europe PMC7
  2019	Fernandes, R. C., Hickey, T. E., Tilley, W. D., & Selth, L. A. (2019). Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer. Endocrine-Related Cancer, 26(5), R237-R257. DOI WoS1
  2019	Holding, A., Giorgi, F., Donnelly, A., Cullen, A., Nagarajan, S., Selth, L., & Markowetz, F. (2019). VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer. Genome Biology, 20(1), 16 pages. DOI Scopus1 WoS2 Europe PMC1
  2019	Holding, A., Giorgi, F., Donnelly, A., Cullen, A., Nagarajan, S., Selth, L., & Markowetz, F. (2019). Correction to: VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer (Genome Biol (2019) 20:91 DOI: 10.1186/s13059-019-1698-z). Genome Biology, 20(1), 2 pages. DOI
  2019	Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., . . . Furic, L. (2019). Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression. The EMBO Journal, OnlinePubl, e101323-1-e101323-19. DOI
  2019	Warren, A., Massie, C., Watt, K., Luko, K., Orafidiya, F., Selth, L., . . . Asim, M. (2019). A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer. Oncogene, 38(7), 1136-1150. DOI Scopus1 WoS1
  2018	Lawrence, M., Obinata, D., Sandhu, S., Selth, L., Wong, S., Porter, L., . . . Frydenberg, M. (2018). Patient-derived models of abiraterone- and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy. European Urology, 74(5), 562-572. DOI Scopus11 WoS10 Europe PMC5
  2018	Holding, A., Giorgi, F., Donnelly, A., Cullen, A., Nagarajan, S., Selth, L., & Markowetz, F. (2018). VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer. DOI Europe PMC1
  2018	Matin, F., Jeet, V., Moya, L., Selth, L., Chambers, S., Clements, J., & Batra, J. (2018). A plasma biomarker panel of four MicroRNAs for the diagnosis of prostate cancer. Scientific Reports, 8(1), 6653-1-6653-15. DOI Scopus12 WoS12 Europe PMC7
  2018	Pillman, K., Phillips, C., Roslan, S., Toubia, J., Dredge, B., Bert, A., . . . Gregory, P. (2018). miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking. EMBO Journal, 37(13), 20 pages. DOI Scopus9 WoS10 Europe PMC4
  2018	Luo, J., Attard, G., Balk, S., Bevan, C., Burnstein, K., Cato, L., . . . Raj, G. (2018). Role of androgen receptor variants in prostate cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting. European Urology, 73(5), 715-723. DOI Scopus23 WoS27 Europe PMC10
  2018	Armstrong, H., Gillis, J., Johnson, I., Nassar, Z., Moldovan, M., Levrier, C., . . . Butler, L. (2018). Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion. Scientific reports, 8(1), 2090-1-2090-14. DOI Scopus5 WoS5 Europe PMC2
  2018	Dhahbi, J. M., Atamna, H., & Selth, L. A. (2018). Data mining of small RNA-Seq suggests an association between prostate cancer and altered abundance of 5' transfer RNA halves in seminal fluid and prostatic tissues. Biomarkers in cancer, 10, 1-8. DOI Europe PMC1
  2018	Centenera, M., Selth, L., Ebrahimie, E., Butler, L., & Tilley, W. (2018). New opportunities for targeting the androgen receptor in prostate cancer. Cold Spring Harbor Perspectives in Medicine, 10(12), 1-19. DOI Scopus7 WoS7 Europe PMC4
  2017	Pedraza-Arévalo, S., Hormaechea-Agulla, D., Gómez-Gómez, E., Requena, M., Selth, L., Gahete, M., . . . Luque, R. (2017). Somatostatin receptor subtype 1 as a potential diagnostic marker and therapeutic target in prostate cancer. Prostate, 77(15), 1499-1511. DOI Scopus5 WoS5 Europe PMC2
  2017	Ponnusamy, S., Coss, C., Thiyagarajan, T., Watts, K., Hwang, D. -J., He, Y., . . . Narayanan, R. (2017). Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer. Cancer Research, 77(22), 6282-6298. DOI Scopus8 WoS7 Europe PMC4
  2017	Leach, D., Panagopoulos, V., Nash, C., Bevan, C., Thomson, A., Selth, L., & Buchanan, G. (2017). Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome. Molecular and Cellular Endocrinology, 439(C), 261-272. DOI Scopus9 WoS9 Europe PMC8
  2017	Selth, L., Das, R., Townley, S., Coutinho, I., Hanson, A., Centenera, M., . . . Tilley, W. (2017). A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer. Oncogene, 36(1), 24-34. DOI Scopus40 WoS41 Europe PMC26
  2017	Das, R., Gregory, P., Fernandes, R., Denis, I., Wang, Q., Townley, S., . . . Selth, L. (2017). MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2. Cancer Research, 77(4), 1021-1034. DOI Scopus29 WoS29 Europe PMC18
  2017	Tse, B., Volpert, M., Ratther, E., Stylianou, N., Nouri, M., McGowan, K., . . . Hollier, B. (2017). Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene, 36(24), 3417-3427. DOI Scopus19 WoS19 Europe PMC6
  2017	Miao, L., Yang, L., Li, R., Rodrigues, D., Crespo, M., Hsieh, J., . . . Raj, G. (2017). Disrupting androgen receptor signaling induces Snail-mediated epithelial-mesenchymal plasticity in prostate cancer. Cancer Research, 77(11), 3101-3112. DOI Scopus14 WoS15 Europe PMC12
  2017	Wang, Q., Selth, L., & Callen, D. (2017). MiR-766 induces p53 accumulation and G2/M arrest by directly targeting MDM4. Oncotarget, 8(18), 29914-29924. DOI Scopus9 WoS12 Europe PMC6
  2017	Paltoglou, S., Das, R., Townley, S., Hickey, T., Tarulli, G., Coutinho, I., . . . Selth, L. (2017). Novel androgen receptor coregulator GRHL2 exerts both oncogenic and antimetastatic functions in prostate cancer. Cancer Research, 77(13), 3417-3430. DOI Scopus14 WoS12 Europe PMC10
  2016	Armstrong, H., Koay, Y., Irani, S., Das, R., Nassar, Z., The Australian Prostate Cancer BioResource., . . . Butler, L. (2016). A novel class of Hsp90 C-terminal modulators have pre-clinical efficacy in prostate tumor cells without induction of a heat shock response. Prostate, 76(16), 1546-1559. DOI Scopus10 WoS9 Europe PMC7
  2016	Roberts, M. J., Richards, R., Chow, C., Schirra, H., Buck, M., Selth, L., . . . Gardiner, R. (2016). PROSTATIC FLUID MRNA AND MICRORNA BIOMARKERS: AN EMERGING PARADIGM FOR NONINVASIVE DIAGNOSIS OF PROSTATE CANCER. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 12, 41.
  2016	Hu, D., Selth, L., Tarulli, G., Meech, R., Wijayakumara, D., Chanawong, A., . . . Hickey, T. (2016). Androgen and estrogen receptors in breast cancer coregulate human UDP-glucuronosyltransferases 2B15 and 2B17. Cancer Research, 76(19), 5881-5893. DOI Scopus20 WoS20 Europe PMC11
  2016	Asim, M., Massie, C., Orafidiya, F., Pértega-Gomes, N., Warren, A., Esmaeili, M., . . . Neal, D. (2016). Choline kinase alpha as an androgen receptor chaperone and prostate cancer therapeutic target. Journal of the National Cancer Institute, 108(5), djv371-1-djv371-13. DOI Scopus15 WoS15 Europe PMC10
  2016	Carter, S., Centenera, M., Tilley, W., Selth, L., & Butler, L. (2016). IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor. BMC Cancer, 16(1), 141-1-141-13. DOI Scopus6 WoS7 Europe PMC5
  2016	Carter, S., Centenera, M., Tilley, W., Selth, L., & Butler, L. (2016). Erratum to: IΚBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor.[BMC Cancer. 2016] 16:141. Doi: 10.1186/s12885-016-2188-2.. BMC Cancer, 16(1), 1 page. DOI Europe PMC1
  2016	Coutinho, I., Day, T., Tilley, W., & Selth, L. (2016). Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence. Endocrine-Related Cancer, 23(12), T179-T197. DOI Scopus41 WoS43 Europe PMC31
  2015	Raj, G., Selth, L., Day, T., & Tilley, W. (2015). Evolution of androgen deprivation therapy. Cancer Forum, 39(3), 189-194.
  2015	Chan, S., Selth, L., Li, Y., Nyquist, M., Miao, L., Bradner, J., . . . Dehm, S. (2015). Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. Nucleic Acids Research, 43(12), 5880-5897. DOI Scopus81 WoS85 Europe PMC68
  2015	Need, E., Selth, L., Trotta, A., Leach, D., Giorgio, L., O'Loughlin, M., . . . Buchanan, G. (2015). The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype. BMC Cancer, 15(1), 791-1-791-17. DOI Scopus12 WoS10 Europe PMC9
  2015	Hickey, T., Irvine, C., Dvinge, H., Tarulli, G., Hanson, A., Ryan, N., . . . Selth, L. (2015). Expression of androgen receptor splice variants in clinical breast cancers. Oncotarget, 6(42), 44728-44744. DOI Scopus40 WoS35 Europe PMC28
  2015	Roberts, M., Chow, C., Schirra, H., Richards, R., Buck, M., Selth, L., . . . Gardiner, R. (2015). Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer. The Prostate, 75(5), 539-549. DOI Scopus23 WoS23 Europe PMC16
  2015	Stegeman, S., Moya, L., Selth, L., Spurdle, A., Clements, J., & Batra, J. (2015). A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer. Endocrine-Related Cancer, 22(2), 265-276. DOI Scopus25 WoS25 Europe PMC22
  2015	Roberts, M., Richards, R., Gardiner, R., & Selth, L. (2015). Seminal fluid: a useful source of prostate cancer biomarkers?. Biomarkers in Medicine, 9(2), 77-80. DOI Scopus8 WoS8 Europe PMC8
  2014	Hu, D., Hickey, T., Irvine, C., Wijayakumara, D., Lu, L., Tilley, W., . . . MacKenzie, P. (2014). Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues. Hormones and Cancer, 5(2), 61-71. DOI Scopus28 WoS26 Europe PMC22
  2014	Das, R., Gregory, P., Hollier, B., Tilley, W., & Selth, L. (2014). Epithelial plasticity in prostate cancer: principles and clinical perspectives. Trends in Molecular Medicine, 20(11), 643-651. DOI Scopus12 WoS14 Europe PMC10
  2014	Selth, L., Roberts, M., Chow, C., Marshall, V., Doi, S., Vincent, A., . . . Gardiner, R. (2014). Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers. Endocrine-Related Cancer, 21(4), L17-L21. DOI Scopus23 WoS20 Europe PMC17
  2014	Li, X., Roslan, S., Johnstone, C., Wright, J., Bracken, C., Anderson, M., . . . Khew-Goodall, Y. (2014). MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways. Oncogene, 33(31), 4077-4088. DOI Scopus79 WoS72 Europe PMC62
  2013	Trotta, A., Need, E., Selth, L., Chopra, S., Pinnock, C., Leach, D., . . . Buchanan, G. (2013). Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation. International Journal of Cancer, 133(12), 2812-2823. DOI Scopus14 WoS13 Europe PMC10
  2013	Selth, L., Townley, S., Bert, A., Stricker, P., Sutherland, P., Horvath, L., . . . Tilley, W. (2013). Circulating microRNAs predict biochemical recurrence in prostate cancer patients. British Journal of Cancer, 109(3), 641-650. DOI Scopus84 WoS84 Europe PMC62
  2013	Larsson, M., Uvell, H., Sandstrom, J., Ryden, P., Selth, L., & Bjorklund, S. (2013). Functional studies of the yeast Med5, Med15 and Med16 mediator tail subunits. PLoS One, 8(8), e73137-1-e73137-10. DOI Scopus9 WoS9 Europe PMC7
  2013	Sapre, N., & Selth, L. (2013). Circulating microRNAs as biomarkers of prostate cancer: the state of play. Prostate Cancer, 2013, 1-10. DOI Europe PMC27
  2013	Gillis, J., Selth, L., Centenera, M., Townley, S., Sun, S., Plymate, S., . . . Butler, L. (2013). Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors. Oncotarget, 4(5), 691-704. DOI Scopus33 WoS31 Europe PMC29
  2013	Chiam, K., Ryan, N., Ricciardelli, C., Day, T., Buchanan, G., Ochnik, A., . . . Bianco-Miotto, T. (2013). Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers. Prostate, 73(2), 182-193. DOI Scopus12 WoS11 Europe PMC9
  2012	Need, E., Selth, L., Harris, T., Birrell, S., Tilley, W., & Buchanan, G. (2012). Research resource: interplay between the genomic and transcriptional networks of androgen receptor and estrogen receptor α in luminal breast cancer cells. Molecular Endocrinology, 26(11), 1941-1952. DOI Scopus46 WoS43 Europe PMC36
  2012	Trotta, A., Need, E., Butler, L., Selth, L., O'Loughlin, M., Coetzee, G., . . . Buchanan, G. (2012). Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client. Journal of Molecular Endocrinology, 49(2), 57-68. DOI Scopus16 WoS16 Europe PMC15
  2012	Moore, N., Buchanan, G., Harris, J., Selth, L., Bianco-Miotto, T., Hanson, A., . . . Tilley, W. (2012). An androgen receptor mutation in the MDA-MB-453 cell line model of molecular apocrine breast cancer compromises receptor activity. Endocrine-Related Cancer, 19(4), 599-613. DOI Scopus31 WoS31 Europe PMC24
  2012	Selth, L., Tilley, W., & Butler, L. (2012). Circulating microRNAs: macro-utility as markers of prostate cancer?. Endocrine-Related Cancer, 19(4), 99-113. DOI Scopus31 WoS29 Europe PMC23
  2012	Thompson, V., Day, T., Bianco-Miotto, T., Selth, L., Han, G., Thomas, M., . . . Tilley, W. (2012). A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease. International Journal of Cancer, 131(3), 662-672. DOI Scopus16 WoS18 Europe PMC12
  2012	Selth, L., Townley, S., Gillis, J., Ochnik, A., Murti, K., Macfarlane, R., . . . Butler, L. (2012). Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease. International Journal of Cancer, 131(3), 652-661. DOI Scopus125 WoS119 Europe PMC88
  2011	Kumar, R., Selth, L., Schulz, R., Tay, B., Neilsen, P., & Callen, D. (2011). Genome-wide mapping of ZNF652 promoter binding sites in breast cancer cells. Journal of Cellular Biochemistry, 112(10), 2742-2747. DOI Scopus12 WoS10 Europe PMC11
  2011	Selth, L., Randles, J., & Ali Rezaian, M. (2011). Erratum: Agrobacterium tumefaciens supports DNA replication of diverse geminivirus types (FEBS Letters (2002) 516 (179-182)). FEBS Letters, 585(24), 4030. DOI
  2010	Selth, L., Sigurdsson, S., & Svejstrup, J. (2010). Transcript elongation by RNA polymerase II. Annual Review of Biochemistry, 79(1), 271-293. DOI Scopus129 WoS129 Europe PMC111
  2010	Kainov, D., Selth, L., Svejstrup, J., Egly, J., & Poterzsman, A. (2010). Interacting partners of the Tfb2 subunit from yeast TFIIH. DNA Repair, 9(1), 33-39. DOI Scopus9 WoS9 Europe PMC6
  2009	Selth, L., Lorch, Y., Ocampo-Hafalla, M., Mitter, R., Shales, M., Krogan, N., . . . Svejstrup, J. (2009). An Rtt109-independent role for Vps75 in transcription-associated nucleosome dynamics. Molecular and Cellular Biology, 29(15), 4220-4234. DOI Scopus24 WoS23 Europe PMC24
  2009	Selth, L., Gilbert, C., & Svejstrup, J. (2009). RNA immunoprecipitation to determine RNA-protein associations in vivo. Cold Spring Harbor Protocols, 4(6), 1-7. DOI Scopus33 Europe PMC22
  2009	Greenwood, C., Selth, L., Dirac-Svejstrup, A., & Svejstrup, J. (2009). An Iron-Sulfur Cluster Domain in Elp3 Important for the Structural Integrity of Elongator. Journal of Biological Chemistry, 284(1), 141-149. DOI Scopus41 WoS34 Europe PMC31
  2009	Eini Gandomani, O., Dogra, S., Selth, L., Dry, I., Randles, J., & Rezaian, M. (2009). Interaction with a Host Ubiquitin-Conjugating Enzyme Is Required for the Pathogenicity of a Geminiviral DNA beta Satellite. Molecular Plant-Microbe Interactions, 22(6), 737-746. DOI Scopus46 WoS42 Europe PMC27
  2007	Selth, L., & Svejstrup, J. (2007). Vps75, a new yeast member of the NAP histone chaperone family. Journal of Biological Chemistry, 282(17), 12358-12362. DOI Scopus53 WoS53 Europe PMC50
  2006	Selth, L., Dogra, S., Rasheed, M., Randles, J., & Rezaian, M. (2006). Identification and characterization of a host reversibly glycosylated peptide that interacts with the Tomato leaf curl virus V1 protein. Plant Molecular Biology, 61(1-2), 297-310. DOI Scopus22 WoS19 Europe PMC14
  2006	Rasheed, M., Selth, L., Koltunow, A., Randles, J., & Rezaian, M. (2006). Single-stranded DNA of Tomato leaf curl virus accumulates in the cytoplasm of phloem cells. Virology, 348(1), 120-132. DOI Scopus22 WoS20 Europe PMC18
  2005	Selth, L., Dogra, S., Rasheed, M., Healy, H., Randles, J., & Rezaian, M. (2005). A NAC domain protein interacts with tomato leaf curl virus replication accessory protein and enhances viral replication. Plant Cell, 17(1), 311-325. DOI Scopus115 WoS105 Europe PMC77
  2004	Selth, L., Randles, J., & Rezaian, M. (2004). Host responses to transient expression of individual genes encoded by Tomato leaf curl virus. Molecular Plant-Microbe Interactions, 17(1), 27-33. DOI Scopus41 WoS33 Europe PMC25
  2002	Selth, L., Randles, J., & Rezaian, M. (2002). Agrobacterium tumefaciens supports DNA replication of diverse geminivirus types. FEBS Letters, 516(1-3), 179-182. DOI Scopus23 WoS25 Europe PMC23

• Book Chapters

  Year	Citation
  2013	Selth, L., Townley, S., Gillis, J., Tilley, W., & Butler, L. (2013). Identification of prostate cancer-associated microRNAs in circulation using a mouse model of disease. In T. Ochiya (Ed.), Circulating MicroRNAs. Methods and Protocols (Vol. 1024, pp. 235-246). UK: Springer. DOI Scopus3 Europe PMC3
  2011	Selth, L., Close, T., & Svejstrup, J. (2011). Studying RNA-protein interactions in vivo by RNA immunoprecipitation. In T. Tollefsbol (Ed.), Epigenetics Protocols (Vol. 791, 2 ed., pp. 253-264). United States: Humana Press. DOI Scopus18 Europe PMC15

• Conference Papers

  Year	Citation
  2018	Matin, F., Jeet, V., Moya, L., Selth, L. A., Chambers, S., Clements, J. A., & Batra, J. (2018). A plasma biomarker panel of four microRNAs for the diagnosis of prostate cancer. In BJU INTERNATIONAL Vol. 122 (pp. 29). Brisbane, AUSTRALIA: WILEY.
  2018	Selth, L. (2018). Toward Improved Treatment of Prostate Cancer: Novel Strategies to Target the Androgen Receptor. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 14 (pp. 26-27). WILEY.

• Conference Items

  Year	Citation
  2019	Winter, J. M., Mustafa, E. H., Wang, S., Selth, L. A., Hickey, T. E., & Tilley, W. D. (2019). Novel and highly selective CDK9 inhibitors suppress proliferation of triple negative breast cancer (TNBC) cells in vitro. Poster session presented at the meeting of CANCER RESEARCH. Atlanta, GA: AMER ASSOC CANCER RESEARCH. DOI
  2018	Daniel, M. L., Hickey, T. E., Carroll, J. S., Tilley, W. D., Selth, L. A., & Dehm, S. M. (2018). Deciphering the regulome of androgen receptor variants in prostate cancer. Poster session presented at the meeting of CANCER RESEARCH. Chicago, IL: AMER ASSOC CANCER RESEARCH. DOI
  2018	Nassar, Z. D., Centenera, M. M., Machiels, J., Zinonos, I., Hanson, A., Bloch, K., . . . Swinnen, J. V. (2018). Lipid elongation in prostate cancer is androgen regulated and a potential therapeutic target. Poster session presented at the meeting of BJU International. Brisbane, Australia: Wiley.
  2017	Selth, L. (2017). TOWARDS IMPROVED PROSTATE CANCER TREATMENT BY EXPLOITING MICRORNAS. Poster session presented at the meeting of ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY.
  2016	Nassar, Z. D., Centenera, M. M., Machiels, J., Polacek, S. J., Bloch, K., Tilley, W. D., . . . Swinnen, J. V. (2016). Androgenic regulation of lipid elongation in prostate cancer. Poster session presented at the meeting of BJU International. Melbourne: Wiley.
  2015	Roberts, M. J., Chow, C. W. K., Schirra, H. J., Richards, R., Buck, M., Selth, L. A., . . . Gardiner, R. A. F. (2015). Diagnostic performance of PCA3, Hepsin and microRNA biomarkers in ejaculate in combination with serum PSA for the detection and triaging of prostate cancer. Poster session presented at the meeting of British Journal of Urology (BJU) International. Adelaide, Australia: Wiley. DOI
  2014	Hickey, T. E., Robinson, J. L., Moore, N. L., Russell, R., Selth, L., Rueda, O., . . . Tilley, W. D. (2014). The androgen receptor restricts estrogen receptor Alpha DNA binding in breast cancer cells. Poster session presented at the meeting of Endocrine Reviews. Chicago: Endocrine Society.
  2014	Roberts, M., Selth, L., Chow, C., Doi, S., Vincent, A., Butler, L., . . . Gardiner, R. (2014). Seminal fluid microRNAs: new, non-invasive biomarkers for prostate cancer. Poster session presented at the meeting of BJU International. Brisbane: Wiley.
  2013	Selth, L., Townley, S., Bert, A., Stricker, P., Sutherland, P., Horvath, L., . . . Tilley, W. (2013). CIRCULATING microRNAs PREDICT BIOCHEMICAL RECURRENCE IN PROSTATE CANCER PATIENTS. Poster session presented at the meeting of ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY-BLACKWELL.

Investigative Cell Biology - Lecturing and supervisor for research placements - 2011-current.

Bachelor of Health Sciences (Advanced) HEALTH 3000A & 3000B - Supervisor for research placements - 2017.

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• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2019	Principal Supervisor	The effect of gleason score at positive surgical margin after radical prostalectory on biochemical recurrence and oncological outcomes.	Master of Philosophy (Surgery)	Master	Part Time	Dr Athul Francis John
  2019	Principal Supervisor	Elucidating the Interplay Between Androgen Receptor Signalling and Lipid Metabolism in Prostate Cancer	Doctor of Philosophy	Doctorate	Full Time	Ms Meiwen Danielle Fang
  2018	Co-Supervisor	Female Germline Formation During Plant Development	Doctor of Philosophy	Doctorate	Full Time	Mr Dayton Christopher Bird
  2017	Principal Supervisor	Interactions between Androgen signalling and the lipid microenvironment in prostate cancer	Doctor of Philosophy	Doctorate	Full Time	Mr Raj Kumar Shrestha
  2017	Principal Supervisor	Development of Microfluidic Technology for Genomic Studies of Circulation Tumor Cells	Doctor of Philosophy	Doctorate	Full Time	Mr Mohammadreza Alizadeh Ghodsi
  2016	Principal Supervisor	Unraveling the regulatory network underlying Androgen Deprivation Therapy- induced cancer stem cell traits in prostate cancer	Doctor of Philosophy	Doctorate	Full Time	Miss Rayzel Candida Fernandes

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2014 - 2014	Principal Supervisor	Curcumin Action in Prostate Cancer Cells and Fibroblasts	Doctor of Philosophy	Doctorate	Full Time	Miss Lauren Giorgio
  2014 - 2017	Co-Supervisor	MicroRNA Mediated Gene Regulation in Cancer	Doctor of Philosophy	Doctorate	Full Time	Ms Qingqing Wang
  2013 - 2016	Co-Supervisor	Elucidating the Molecular Action of Synthetic Heat Shock Protein 90 Inhibitors in Prostate Cancer	Doctor of Philosophy	Doctorate	Full Time	Miss Heather Krista Armstrong
  2013 - 2016	Principal Supervisor	The Role of microRNA-194 and microRNA-375 in Prostate Cancer Metastasis	Doctor of Philosophy	Doctorate	Full Time	Dr Rajdeep Das
  2011 - 2015	Co-Supervisor	Combinatorial Targeting of the Androgen Receptor for Prostate Cancer Therapy	Doctor of Philosophy	Doctorate	Full Time	Miss Sarah Carter

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• Committee Memberships

  Date	Role	Committee	Institution	Country
  2016 - ongoing	Member	Adelaide Health and Medical School Research Reference Group	—	—
  2015 - ongoing	Member	Faculty of Health Sciences Early/Mid Career Researcher Working Group	University of Adelaide	—
  2014 - ongoing	Member	University of Adelaide Institutional Biosafety Committee	University of Adelaide	—

• Editorial Boards

  Date	Role	Editorial Board Name	Institution	Country
  2017 - ongoing	Board Member	Endocrine-Related Cancer	—	—
  2015 - ongoing	Editor	Scientific Reports (Nature Publishing Group)	—	—

• Position: Senior Research Fellow - DRMCRL
• Phone: 83137860
• Email: luke.selth@adelaide.edu.au
• Campus: North Terrace
• Building: Adelaide Health and Medical Sciences, floor 8
• Room: WS8058.02
• Org Unit: Medical Specialties