Dr Liliana Ciobanu

Adjunct Associate Lecturer

Adelaide Medical School

Faculty of Health and Medical Sciences

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Contact

In my research, I investigate the molecular underpinnings of cognition and psychiatric disorders. I'm interested in understanding what genes play a role in major depression, schizophrenia, and bipolar disorder, to what extent they overlap with cognitive functioning, and how the interaction between these genes affects biological pathways implicated in these psychiatric conditions. In particular, I'm interested in utilising integrative approaches allowing to bridge multiple levels of -omics abstraction with clinical data. This may provide new insights into the pathophysiology of psychiatric conditions and cognition, identify clinically relevant biological markers of disease and suggest novel therapeutic targets. I use next‐generation sequencing (NGS) and a range of statistical and bioinformatics techniques from classical candidate gene association analysis to genome-wide network approach and machine learning.

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Appointments

Date	Position	Institution name
2020	Grant-Funded Researcher	The University of Adelaide
2019	Adjunct Associate Lecturer	The University of Adelaide
2018 - 2020	Research Associate: Biostatistics and Epidemiology	University of South Australia
2014 - 2019	PhD candidate	The University of Adelaide

Language Competencies

Language Competency
Russian Can read, write, speak, understand spoken and peer review
Education

Date Institution name Country Title
— The University of Adelaide Australia PhD
Research Interests

Bioinformatics Biostatistics Gene Expression Genetics Genomics Health Policy Innate Immunity Mental Health Psychiatry Public Health Systems Biology

Language	Competency
Russian	Can read, write, speak, understand spoken and peer review

Date	Institution name	Country	Title
—	The University of Adelaide	Australia	PhD

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Journals

Year	Citation
2020	Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2020). Downregulated transferrin receptor in the blood predicts recurrent MDD in the elderly cohort: a fuzzy forests approach. Journal of Affective Disorders, 267, 42-48. DOI
2019	Orpana, H., Marczak, L., Arora, M., Abbasi, N., Abdulkader, R., Abebe, Z., . . . Jha, R. (2019). Global, regional, and national burden of suicide mortality 1990 to 2016: Systematic analysis for the Global Burden of Disease Study 2016. BMJ (Online), 364(1), 11 pages. DOI Scopus15 WoS32 Europe PMC8
2018	Roth, G., Abate, D., Abate, K., Abay, S., Abbafati, C., Abbasi, N., . . . Badawi, A. (2018). Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1736-1788. DOI Scopus622 WoS401 Europe PMC137
2018	Lozano, R., Fullman, N., Abate, D., Abay, S., Abbafati, C., Abbasi, N., . . . Appiah, L. (2018). Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 2091-2138. DOI Scopus65 WoS63 Europe PMC26
2018	Dicker, D., Nguyen, G., Abate, D., Abate, K., Abay, S., Abbafati, C., . . . Opio, J. (2018). Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1684-1735. DOI Scopus157 WoS95 Europe PMC52
2018	Roth, G., Abate, D., Abate, K., Abay, S., Abbafati, C., Abbasi, N., . . . Badawi, A. (2018). Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7)). The Lancet, 392(10160), 2170. DOI
2018	Charara, R., Elbcheraoui, C., Khalil, I., Moradi-Lakeh, M., Afshin, A., Kassebaum, N., . . . Larson, H. (2018). The burden of mental disorders in the Eastern Mediterranean region, 1990–2015: findings from the global burden of disease 2015 study. International Journal of Public Health, 63(Suppl 1), 25-37. DOI Scopus11 WoS10 Europe PMC2
2018	Khalil, I., Collison, M., El Bcheraoui, C., Charara, R., Moradi-Lakeh, M., Afshin, A., . . . Magdy Abd El Razek, M. (2018). Maternal mortality and morbidity burden in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study. International Journal of Public Health, 63(Suppl 1), 47-61. DOI Scopus4 WoS3
2018	Fullman, N., Yearwood, J., Abay, S., Abbafati, C., Abd-Allah, F., Abdela, J., . . . Ciobanu, L. (2018). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016. The Lancet, 391(10136), 2236-2271. DOI Scopus129 WoS108 Europe PMC33
2018	Griswold, M., Fullman, N., Hawley, C., Arian, N., Zimsen, S., Tymeson, H., . . . Ciobanu, L. (2018). Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 392(10152), 1015-1035. DOI Scopus413 WoS375 Europe PMC101
2018	Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2018). Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults. Journal of Psychiatric Research, 107, 19-27. DOI Scopus3 WoS3 Europe PMC1
2018	James, S., Abate, D., Abate, K., Abay, S., Abbafati, C., Abbasi, N., . . . Bali, A. (2018). Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1789-1858. DOI Scopus748 WoS632 Europe PMC156
2018	Murray, C., Callender, C., Kulikoff, X., Srinivasan, V., Abate, D., Abate, K., . . . Atique, S. (2018). Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1995-2051. DOI Scopus68 WoS51 Europe PMC18
2018	Ciobanu, L., Ferrari, A., Erskine, H., Santomauro, D., Charlson, F., Leung, J., . . . Baune, B. (2018). The prevalence and burden of mental and substance use disorders in Australia: Findings from the Global Burden of Disease Study 2015. The Australian and New Zealand journal of psychiatry, 52(5), 483-490. DOI Scopus5 WoS4 Europe PMC1
2017	Stacey, D., Ciobanu, L., & Baune, B. (2017). A systematic review on the association between inflammatory genes and cognitive decline in non-demented elderly individuals. European Neuropsychopharmacology, 27(6), 568-588. DOI Scopus10 WoS8 Europe PMC3
2017	Afshin, A., Forouzanfar, M., Reitsma, M., Sur, P., Estep, K., Lee, A., . . . Noubiap, J. (2017). Health effects of overweight and obesity in 195 countries over 25 years. New England Journal of Medicine, 377(1), 13-27. DOI Scopus1395 WoS1220 Europe PMC597
2017	Barber, R., Fullman, N., Sorensen, R., Bollyky, T., McKee, M., Nolte, E., . . . Beyene, T. (2017). Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: A novel analysis from the global burden of disease study 2015. The Lancet, 390(10091), 231-266. DOI Scopus197 WoS170 Europe PMC88
2017	Hay, S., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., . . . Olagunju, A. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1260-1344. DOI Scopus669 WoS652 Europe PMC321
2017	Vos, T., Abajobir, A., Abbafati, C., Abbas, K., Abate, K., Abd-Allah, F., . . . Opio, J. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1211-1259. DOI Scopus1549 WoS1286 Europe PMC661
2017	Naghavi, M., Abajobir, A., Abbafati, C., Abbas, K., Abd-Allah, F., Abera, S., . . . Chibueze, C. (2017). Global, regional, and national age-sex specifc mortality for 264 causes of death, 1980-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1151-1210. DOI Scopus1342 WoS1274 Europe PMC595
2017	Wang, H., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., . . . Bennett, J. (2017). Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1084-1150. DOI Scopus271 WoS260 Europe PMC151
2017	Kassebaum, N., Kyu, H., Zoeckler, L., Olsen, H., Thomas, K., Pinho, C., . . . Goto, A. (2017). Child and adolescent health from 1990 to 2015: Findings from the global burden of diseases, injuries, and risk factors 2015 study. JAMA Pediatrics, 171(6), 573-592. DOI Scopus102 WoS100 Europe PMC63
2017	Reitsma, M., Fullman, N., Ng, M., Salama, J., Abajobir, A., Abate, K., . . . Tefera, Y. (2017). Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015. The Lancet, 389(10082), 1885-1906. DOI Scopus407 WoS387 Europe PMC179
2017	Kassebaum, N., Barber, R., Dandona, L., Hay, S., Larson, H., Lim, S., . . . Ajala, O. (2017). Erratum: Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 (The Lancet (2016) 388(10053) (1775–1812)(S0140673616314702)(10.1016/S0140-6736(16)31470-2)). The Lancet, 389(10064), e1. DOI
2017	Wang, H., Bhutta, Z., Coates, M., Coggeshall, M., Dandona, L., Diallo, K., . . . Bazargan-Hejazi, S. (2017). Erratum: Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015 (The Lancet (2016) 388(10053) (1725–1774)(S0140673616315756)(10.1016/S0140-6736(16)31575-6)). The Lancet, 389(10064), e1. DOI
2017	Kassebaum, N., Barber, R., Dandona, L., Hay, S., Larson, H., Lim, S., . . . Bärnighausen, T. (2017). Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Obstetrical and Gynecological Survey, 72(1), 11-13. DOI
2016	Wang, H., Wolock, T., Carter, A., Nguyen, G., Kyu, H., Gakidou, E., . . . CÃ rdenas, R. (2016). Erratum: Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: The Global Burden of Disease Study 2015 (The Lancet HIV (2016) 3 (e361-e387) PII: S235230181630087X DOI: 10.1016/S2352-3018(16)30087-X). The Lancet HIV, 3(9), e408. DOI Europe PMC1
2016	Vos, T., Allen, C., Arora, M., Barber, R., Bhutta, Z., Brown, A., . . . Amberbir, A. (2016). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1545-1602. DOI Scopus2244 WoS2156 Europe PMC1087
2016	Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., . . . Alexander, L. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459-1544. DOI Scopus2281 WoS2171 Europe PMC1249
2016	Melaku, Y. (2016). Global, regional, and national comparative risk assessment of 79 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1659-1724. DOI Scopus1437 WoS1258 Europe PMC641
2016	Kassebaum, N., Arora, M., Barber, R., Bhutta, Z., Brown, J., Carter, A., . . . Amberbir, A. (2016). Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1603-1658. DOI Scopus865 WoS815 Europe PMC468
2016	Lim, S., Allen, K., Bhutta, Z., Dandona, L., Forouzanfar, M., Fullman, N., . . . Bayou, T. (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1813-1850. DOI Scopus204 WoS62 Europe PMC107
2016	GBF 2015 Maternal Mortality Collaborators., Wang, H., Amare, A., Hancock, J., Lalloo, R., Melaku, Y., & Tessema, G. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725-1774. DOI Scopus253 WoS41 Europe PMC156
2016	GBF 2015 Maternal Mortality Collaborators., Kassebaum, N., Amare, A., Ciobanu, L., Hancock, J., Lalloo, R., . . . Tessema, G. (2016). Global, regional, and national levels of maternal mortality, 1990–2015 : a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1775-1812. DOI Scopus278 WoS268 Europe PMC114
2016	Wang, H., Wolock, T., Carter, A., Nguyen, G., Kyu, H., Gakidou, E., . . . Amare, A. (2016). Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. The Lancet HIV, 3(8), 361-387. DOI Scopus296 WoS277 Europe PMC196
2016	Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2016). Differential gene expression in brain and peripheral tissues in depression across the life span: a review of replicated findings. Neuroscience and Biobehavioral Reviews, 71, 281-293. DOI Scopus11 WoS9 Europe PMC4
2016	Lim, S. S., Allen, K., Bhutta, Z. A., Dandona, L., Forouzanfar, M. H., Fullman, N., . . . Murray, C. J. (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. LANCET, 388(10053), 1813-1850. DOI WoS203
2016	Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., . . . Murray, C. J. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET, 388(10053), 1725-1774. WoS215

Book Chapters

Year	Citation
2020	Ciobanu, L., Cearns, M., & Baune, B. (2020). Gene coexpression network and machine learning in personalized psychiatry. In B. Baune (Ed.), Personalized Psychiatry (pp. 385-392). London, United Kingdom: Academic Press. DOI
2018	Ciobanu, L. G., & Baune, B. (2018). Gene expression of inflammation markers in depression. In B. T. Baune (Ed.), Inflammation and immunity in depression: basic science and clinical applications (pp. 199-222). London: Academic Press. DOI

Conference Items

Year	Citation
2017	Ciobanu, L., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. (2017). TRANSCRIPTOME SIGNATURE OF DEPRESSION. Poster session presented at the meeting of EUROPEAN NEUROPSYCHOPHARMACOLOGY. Jerusalem, ISRAEL: ELSEVIER SCIENCE BV. DOI
2017	Ciobanu, L., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. (2017). GENOME-WIDE GENE EXPRESSION SIGNATURE OF DEPRESSION. Poster session presented at the meeting of EUROPEAN NEUROPSYCHOPHARMACOLOGY. Jerusalem, ISRAEL: ELSEVIER SCIENCE BV. DOI WoS1
2017	Ciobanu, L., Ori, A., Pagliaroli, L., Polimanti, R., Spindola, L., Vincent, J., & Cormack, F. (2017). Summaries of plenary and selected symposia sessions at the XXIV World Congress of Psychiatric Genetics; Jerusalem, Israel; 30 October 2016-3 November 2016. Poster session presented at the meeting of Psychiatric Genetics. England. DOI

Royal Adelaide Hospital Research Foundation 2018 Project Grant. Clark SR, Ciobanu L, Baune BT. “Patterns of gene expression in chronic psychosis associated with cognitive and general function.” (AUD 50,000)

Australian Defence Force 2020. Ciobanu L, Clark SR, Aidman E. "Structural and functional correlates of cognitive functioning to inform on modifiable factors of cognitive fitness." (AUD 141,660)

Adjunct Associate Lecturer (Fundamentals of Biological Psychiatry, PSYCHIAT 3200)

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Other Supervision Activities

Date	Role	Research Topic	Location	Program	Supervision Type	Student Load	Student Name
2018 - 2018	Co-Supervisor	Patterns of gene expression in chronic psychosis associated with cognitive and general function	The University of Adelaide	—	Honours	Full Time	Edward Luong

Position: Adjunct Associate Lecturer
Email: liliana.ciobanu@adelaide.edu.au
Campus: North Terrace
Building: Adelaide Health and Medical Sciences, floor 6
Org Unit: Adelaide Medical School

Dr Liliana Ciobanu

Appointments

Language Competencies

Education

Research Interests

Journals

Book Chapters

Conference Items

Other Supervision Activities

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