
Dr Liliana Ciobanu
NHMRC Grant-Funded Researcher C
Adelaide Medical School
Faculty of Health and Medical Sciences
As a leader of the Cognitive Genomics research group, I investigate the molecular underpinnings of cognitive functioning in healthy individuals as well as in people with psychiatric disorders. My current work is focused on examining the genome-informed structure of cognitive functioning to develop biology-based assessment tools for cognitive functioning in high-performance occupations. I'm also interested in understanding what genes play a role in major depression, schizophrenia, and bipolar disorder, to what extent they overlap with cognitive functioning, and how the interaction between these genes affects biological pathways implicated in these psychiatric conditions. In particular, I'm interested in utilising integrative approaches allowing to bridge multiple levels of -omics abstraction with clinical data. This may provide new insights into the pathophysiology of psychiatric conditions and cognition, identify clinically relevant biological markers of disease and suggest novel therapeutic targets. I use next‐generation sequencing (NGS) and a range of statistical and bioinformatics techniques from classical candidate gene association analysis to genome-wide network approach and machine learning. Available for HDR supervision.
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Appointments
Date Position Institution name 2020 - ongoing Grant-Funded Researcher The University of Adelaide 2019 - ongoing Adjunct Associate Lecturer The University of Adelaide 2018 - 2020 Research Associate: Biostatistics and Epidemiology University of South Australia 2014 - 2019 PhD candidate The University of Adelaide -
Language Competencies
Language Competency Russian Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title The University of Adelaide Australia PhD -
Research Interests
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Journals
Year Citation 2021 Kendrick, P. J., Reitsma, M. B., Abbasi-Kangevari, M., Abdoli, A., Abdollahi, M., Abedi, A., . . . Gakidou, E. (2021). Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. The Lancet Public Health, 6(7), e482-e499.
Scopus8 WoS3 Europe PMC22021 GBD 2019 Under-5 Mortality Collaborators., Bhandari, D., Ciobanu, L., Gill, T., Lassi, Z., Tessema, G., . . . Ahmed, M. (2021). Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019. The Lancet, 398(10303), 870-905.
Scopus41 WoS41 Europe PMC222020 Wong, M. W., Thalamuthu, A., Braidy, N., Mather, K. A., Liu, Y., Ciobanu, L., . . . Sachdev, P. S. (2020). Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins. eLife, 9, 1-28.
Scopus2 WoS2 Europe PMC12020 GBD 2019 Universal Health Coverage Collaborators., Bhandari, D., Ciobanu, L., Azzopardi, P., Baune, B., Lalloo, R., . . . Gill, T. (2020). Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1250-1284.
Scopus111 WoS130 Europe PMC612020 GBD 2019 Risk Factors Collaborators., Bhandari, D., Baune, B., Lalloo, R., Noubiap Nzeale,, J. J., Ciobanu, L., & Lassi, Z. (2020). Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1223-1249.
Scopus954 WoS629 Europe PMC4972020 GBD 2019 Diseases and Injuries Collaborators., Baune, B., Bhandari, D., Ciobanu, L., Lalloo, R., Lassi, Z., & Noubiap Nzeale, J. (2020). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1204-1222.
Scopus1693 WoS1529 Europe PMC9572020 Murray, C. J. L., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasi-Kangevari, M., Abd-Allah, F., . . . Badiye, A. D. (2020). Five insights from the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1135-1159.
Scopus112 WoS115 Europe PMC422020 Wang, H., Abbas, K. M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., . . . Noubiap Nzeale, J. (2020). Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1160-1203.
Scopus227 WoS219 Europe PMC1322020 Ciobanu, L. G., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. T. (2020). Downregulated transferrin receptor in the blood predicts recurrent MDD in the elderly cohort: a fuzzy forests approach. Journal of Affective Disorders, 267, 42-48.
Scopus5 WoS7 Europe PMC42019 Orpana, H., Marczak, L., Arora, M., Abbasi, N., Abdulkader, R., Abebe, Z., . . . Jha, R. (2019). Global, regional, and national burden of suicide mortality 1990 to 2016: Systematic analysis for the Global Burden of Disease Study 2016. BMJ (Online), 364(1), 11 pages.
Scopus71 WoS586 Europe PMC1442018 Roth, G. A., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., . . . Badawi, A. (2018). Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7)). The Lancet, 392(10160), 2170.
Scopus3 WoS42018 Fullman, N., Yearwood, J., Abay, S., Abbafati, C., Abd-Allah, F., Abdela, J., . . . Ciobanu, L. (2018). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016. The Lancet, 391(10136), 2236-2271.
Scopus399 WoS380 Europe PMC2122018 Charara, R., Elbcheraoui, C., Khalil, I., Moradi-Lakeh, M., Afshin, A., Kassebaum, N., . . . Larson, H. (2018). The burden of mental disorders in the Eastern Mediterranean region, 1990–2015: findings from the global burden of disease 2015 study. International Journal of Public Health, 63(Suppl 1), 25-37.
Scopus30 WoS28 Europe PMC122018 Khalil, I., Collison, M., El Bcheraoui, C., Charara, R., Moradi-Lakeh, M., Afshin, A., . . . Magdy Abd El Razek, M. (2018). Maternal mortality and morbidity burden in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study. International Journal of Public Health, 63(Suppl 1), 47-61.
Scopus7 WoS9 Europe PMC22018 Griswold, M., Fullman, N., Hawley, C., Arian, N., Zimsen, S., Tymeson, H., . . . Ciobanu, L. (2018). Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 392(10152), 1015-1035.
Scopus1165 WoS1143 Europe PMC5622018 Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2018). Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults. Journal of Psychiatric Research, 107, 19-27.
Scopus16 WoS15 Europe PMC62018 Roth, G., Abate, D., Abate, K., Abay, S., Abbafati, C., Abbasi, N., . . . Badawi, A. (2018). Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1736-1788.
Scopus2771 WoS2428 Europe PMC16162018 Lozano, R., Fullman, N., Abate, D., Abay, S., Abbafati, C., Abbasi, N., . . . Appiah, L. (2018). Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 2091-2138.
Scopus218 WoS206 Europe PMC1272018 Dicker, D., Nguyen, G., Abate, D., Abate, K., Abay, S., Abbafati, C., . . . Opio, J. (2018). Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1684-1735.
Scopus445 WoS429 Europe PMC2662018 James, S. L., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., . . . Olagunju, A. (2018). Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1789-1858.
Scopus4481 WoS3241 Europe PMC24392018 Murray, C. J. L., Callender, C. S. K. H., Kulikoff, X. R., Srinivasan, V., Abate, D., Abate, K. H., . . . Atique, S. (2018). Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1995-2051.
Scopus201 WoS212 Europe PMC1132018 Ciobanu, L., Ferrari, A., Erskine, H., Santomauro, D., Charlson, F., Leung, J., . . . Baune, B. (2018). The prevalence and burden of mental and substance use disorders in Australia: Findings from the Global Burden of Disease Study 2015. The Australian and New Zealand journal of psychiatry, 52(5), 483-490.
Scopus20 WoS17 Europe PMC92017 Reitsma, M., Fullman, N., Ng, M., Salama, J., Abajobir, A., Abate, K., . . . Tefera, Y. (2017). Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015. The Lancet, 389(10082), 1885-1906.
Scopus906 WoS861 Europe PMC5012017 Afshin, A., Forouzanfar, M., Reitsma, M., Sur, P., Estep, K., Lee, A., . . . Noubiap, J. (2017). Health effects of overweight and obesity in 195 countries over 25 years. New England Journal of Medicine, 377(1), 13-27.
Scopus3035 WoS2826 Europe PMC16312017 Barber, R. M., Fullman, N., Sorensen, R. J. D., Bollyky, T., McKee, M., Nolte, E., . . . Beyene, T. J. (2017). Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: A novel analysis from the global burden of disease study 2015. The Lancet, 390(10091), 231-266.
Scopus331 WoS300 Europe PMC1752017 Naghavi, M., Abajobir, A., Abbafati, C., Abbas, K., Abd-Allah, F., Abera, S., . . . Chibueze, C. (2017). Global, regional, and national age-sex specifc mortality for 264 causes of death, 1980-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1151-1210.
Scopus2592 WoS2492 Europe PMC14852017 Hay, S., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., . . . Olagunju, A. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1260-1344.
Scopus1169 WoS1439 Europe PMC6672017 Vos, T., Abajobir, A., Abbafati, C., Abbas, K., Abate, K., Abd-Allah, F., . . . Opio, J. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1211-1259.
Scopus3498 WoS2679 Europe PMC19202017 Wang, H., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., . . . Bennett, J. (2017). Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1084-1150.
Scopus427 WoS407 Europe PMC2742017 Stacey, D., Ciobanu, L., & Baune, B. (2017). A systematic review on the association between inflammatory genes and cognitive decline in non-demented elderly individuals. European Neuropsychopharmacology, 27(6), 568-588.
Scopus15 WoS15 Europe PMC62017 Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., . . . Bazargan-Hejazi, S. (2017). Erratum: Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015 (The Lancet (2016) 388(10053) (1725–1774)(S0140673616315756)(10.1016/S0140-6736(16)31575-6)). The Lancet, 389(10064), e1.
2017 Kassebaum, N. J., Barber, R. M., Dandona, L., Hay, S. I., Larson, H. J., Lim, S. S., . . . Bärnighausen, T. (2017). Erratum: Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 (The Lancet (2016) 388(10053) (1775–1812)(S0140673616314702)(10.1016/S0140-6736(16)31470-2)). The Lancet, 389(10064), e1.
2017 Kassebaum, N., Kyu, H., Zoeckler, L., Olsen, H., Thomas, K., Pinho, C., . . . Goto, A. (2017). Child and adolescent health from 1990 to 2015: Findings from the global burden of diseases, injuries, and risk factors 2015 study. JAMA Pediatrics, 171(6), 573-592.
Scopus211 WoS194 Europe PMC1372017 Kassebaum, N. J., Barber, R. M., Dandona, L., Hay, S. I., Larson, H. J., Lim, S. S., . . . Bärnighausen, T. (2017). Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Obstetrical and Gynecological Survey, 72(1), 11-13.
Scopus22017 Hay, S. I., Jayaraman, S. P., Truelsen, T., Sorensen, R. J. D., Millear, A., Giussani, G., & Beghi, E. (2017). GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015 (vol 388, pg 1545, 2016). LANCET, 389(10064), E1.
WoS7002016 Wang, H., Wolock, T. M., Carter, A., Nguyen, G., Kyu, H. H., Gakidou, E., . . . Cárdenas, R. (2016). Erratum: Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: The Global Burden of Disease Study 2015 (The Lancet HIV (2016) 3 (e361-e387) PII: S235230181630087X DOI: 10.1016/S2352-3018(16)30087-X). The Lancet HIV, 3(9), e408.
Europe PMC12016 Wang, H., Wolock, T., Carter, A., Nguyen, G., Kyu, H., Gakidou, E., . . . Amare, A. (2016). Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. The Lancet HIV, 3(8), 361-387.
Scopus403 WoS390 Europe PMC2932016 Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2016). Differential gene expression in brain and peripheral tissues in depression across the life span: a review of replicated findings. Neuroscience and Biobehavioral Reviews, 71, 281-293.
Scopus16 WoS17 Europe PMC82016 Melaku, Y. A. (2016). Global, regional, and national comparative risk assessment of 79 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1659-1724.
Scopus2543 WoS2099 Europe PMC13092016 Lim, S., Allen, K., Bhutta, Z., Dandona, L., Forouzanfar, M., Fullman, N., . . . Bayou, T. (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1813-1850.
Scopus301 WoS62 Europe PMC1582016 Kassebaum, N., Arora, M., Barber, R., Bhutta, Z., Brown, J., Carter, A., . . . Amberbir, A. (2016). Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1603-1658.
Scopus1311 WoS1145 Europe PMC7612016 Vos, T., Allen, C., Arora, M., Barber, R., Bhutta, Z., Brown, A., . . . Amberbir, A. (2016). Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1545-1602.
Scopus4000 WoS3728 Europe PMC21382016 GBF 2015 Maternal Mortality Collaborators., Wang, H., Amare, A., Hancock, J., Lalloo, R., Melaku, Y., & Tessema, G. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725-1774.
Scopus427 WoS41 Europe PMC2812016 GBF 2015 Maternal Mortality Collaborators., Kassebaum, N., Amare, A., Ciobanu, L., Hancock, J., Lalloo, R., . . . Azzopardi, P. (2016). Global, regional, and national levels of maternal mortality, 1990–2015 : a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1775-1812.
Scopus516 WoS498 Europe PMC2812016 Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., . . . Alexander, L. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459-1544.
Scopus3661 WoS2957 Europe PMC21652016 Lim, S. S., Allen, K., Bhutta, Z. A., Dandona, L., Forouzanfar, M. H., Fullman, N., . . . Murray, C. J. (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. LANCET, 388(10053), 1813-1850.
WoS2802016 Wang, H., Bhutta, Z. A., Coates, M. M., Coggeshall, M., Dandona, L., Diallo, K., . . . Murray, C. J. L. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET, 388(10053), 1725-1774.
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Book Chapters
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Conference Papers
Year Citation 2021 Ciobanu, L., Heathcote, A., Breen, J., Rogasch, N., Stankov, L., Clark, S., & Aidman, E. (2021). From Genes to Personalised Cognitive Training: Mapping the Genetic Architectures of Cognitive Functioning. In APPLYING NEUROSCIENCE TO PERFORMANCE: FROM REHABILITATION TO HUMAN COGNITIVE AUGMENTATION. Rome, Italy. -
Conference Items
Year Citation 2021 Ciobanu, L., Stankov, L., Heathcote, A., Clark, S., Breen, J., Rogasch, N., . . . Aidman, E. (2021). Mapping the genetic architectures of cognitive functioning. Poster session presented at the meeting of GeneMappers 2021. Virtual. 2020 Ciobanu, L., Schubert, O., Amare, A., Jawahar, C., Lawrence-Woods, E., Mills, N., . . . Aidman, E. (2020). P9. MAPPING THE GENETIC ARCHITECTURES OF COGNITIVE FITNESS: CAN GWAS DATA DIFFERENTIATE EXECUTIVE FUNCTIONING FROM GENERAL COGNITIVE ABILITY?. Poster session presented at the meeting of Nature Neurogenetics. New York. 2020 Ciobanu, L., Schubert, K. O., Amare, A., Jawahar, C., Mills, N., Knight, M., . . . Aidman, E. (2020). Genetic Pathways of Cognitive Performance are Overlapping but Distinct for General Intelligence and Executive Functioning Tasks. Poster session presented at the meeting of 2020 Virtual World Congress of Psychiatric Genetics. Virtual. 2020 Ciobanu, L., Schubert, K. O., Amare, A., Jawahar, C., Lawrence-Woods, E., Knight, M., . . . Aidman, E. (2020). Genetic Markers of Cognitive Fitness. Poster session presented at the meeting of Defence Human Sciences Symposium 2020. online. 2017 Ciobanu, L. G., Ori, A. P. S., Pagliaroli, L., Polimanti, R., Spindola, L. M., Vincent, J. B., & Cormack, F. K. (2017). Summaries of plenary and selected symposia sessions at the XXIV World Congress of Psychiatric Genetics; Jerusalem, Israel; 30 October 2016-3 November 2016. Poster session presented at the meeting of Psychiatric Genetics. England: Ovid Technologies (Wolters Kluwer Health).
2017 Ciobanu, L., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. (2017). TRANSCRIPTOME SIGNATURE OF DEPRESSION. Poster session presented at the meeting of EUROPEAN NEUROPSYCHOPHARMACOLOGY. Jerusalem, ISRAEL: ELSEVIER SCIENCE BV.
2017 Ciobanu, L., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. (2017). GENOME-WIDE GENE EXPRESSION SIGNATURE OF DEPRESSION. Poster session presented at the meeting of EUROPEAN NEUROPSYCHOPHARMACOLOGY. Jerusalem, ISRAEL: ELSEVIER SCIENCE BV.
WoS1
Royal Adelaide Hospital Research Foundation 2018 Project Grant. Clark SR, Ciobanu L, Baune BT. “Patterns of gene expression in chronic psychosis associated with cognitive and general function.” (AUD 50,000)
Australian Defence Force 2020. Ciobanu L, Clark SR, Aidman E. "Structural and functional correlates of cognitive functioning to inform on modifiable factors of cognitive fitness." (AUD 141,660)
Adjunct Associate Lecturer (Fundamentals of Biological Psychiatry, PSYCHIAT 3200)
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Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2018 - 2018 Co-Supervisor Patterns of gene expression in chronic psychosis associated with cognitive and general function The University of Adelaide Honours Full Time Edward Luong
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