Dr Khalida Perveen

School of Medicine

College of Health


Dr Perveen has a Master of Philosophy (2012 in molecular/medical microbiology, Quaid-i-Azam University, Pakistan) and PhD (2023, in Immunology, the University of Adelaide), supervised by Prof. Antonio Ferrante in the Department of Immunopathology, SA Pathology at the Women’s and Children’s Hospital. Her research activity, which continues from her PhD studies, is focused on the characterization of early development of the newborn’s immune system. The work has led to the discovery that a signaling protein called protein Kinase C zeta (PKCζ) regulates the development and maturation of T cells with a potential to be stimulated towards either a Th1 or Th2 cytokine profile. The work has identified that a significant number of babies are born with low levels of PKCζ which predisposes them to a high risk of developing allergic diseases. Consistent with development towards a Th2 cytokine propensity. Interestingly, this low PKCζ has a short transient period and the present research results suggest that it is amenable to regulation with nutrients such as omega-3 polyunsaturated fatty acids (fish oil). Current research focuses on the characterisation of the window of opportunity of the low PKCζ and implements strategies for intervention to tackle the allergy epidemic facing our community today.

Date Position Institution name
2024 - 2025 Visiting Associate University of Adelaide
2022 - 2024 Research Assistant University of Adelaide
2019 - 2023 Grant Funded Scientist South Australia Pathology

Date Type Title Institution Name Country Amount
2022 Award Invest for Success grant-2022 Robinson Research Institute, The University of Adelaide Australia 30000
2020 Scholarship Australian Government Research Training Program Department of Education, Australian Government Australia -
2016 Scholarship Adelaide Scholarships International University of Adelaide Australia -
2011 Scholarship Indigenous 5000 PhD Fellowships Scheme Higher Education Commission Pakistan -

Year Citation
2025 Ho, W. D., Perveen, K., Quach, A., Hii, C. S., & Ferrante, A. (2025). Innate recognition and phagocytosis of zymosan by human neutrophils require cell priming in a p38-dependent manner. JOURNAL OF IMMUNOLOGY, 15 pages.
DOI
2024 Lao, Y., Quach, A., Perveen, K., Hii, C., & Ferrante, A. (2024). Effects of blood sample storage time, temperature, anti-coagulants and blood stabiliser on lymphocyte phenotyping. Pathology, 56(4), 571-576.
DOI Scopus2 WoS1 Europe PMC1
2024 Perveen, K., & Ferrante, A. (2024). Protein Kinase C Isozyme Immaturity/Deficiency in Cord Blood Monocytes and Neutrophils. International Journal of Molecular Sciences, 25(21), 11665-1-11665-12.
DOI
2023 Perveen, K., Quach, A., Stark, M. J., Prescott, S., Barry, S. C., Hii, C. S., & Ferrante, A. (2023). PKCζ activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensity.. Immunology, 170(3), 359-373.
DOI Scopus3 WoS2 Europe PMC2
2022 Small, A. G., Perveen, K., Putty, T., Patel, N., Quinn, P., Wechalekar, M. D., . . . Ferrante, A. (2022). Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin.. Frontiers in Immunology, 13, 840510-1-840510-13.
DOI Scopus8 WoS9 Europe PMC5
2021 Ahmed, H., Fehmi, S., Rahim, A., Perveen, K., Baig, N., & Jahanara. (2021). To Evaluate the Dimensions of Each Lobe and Total Volume of Thyroid Gland by Ultrasonography Among Pregnant and Non-Pregnant Women in Local Population of Karachi. ANNALS ABBASI SHAHEED HOSPITAL & KARACHI MEDICAL & DENTAL COLLEGE, 26(1), 251-256.
2021 Acevedo, N., Alashkar Alhamwe, B., Caraballo, L., Ding, M., Ferrante, A., Garn, H., . . . van Esch, B. C. A. M. (2021). Perinatal and early-life nutrition, epigenetics, and allergy. Nutrients, 13(3), 1-50.
DOI Scopus132 WoS123 Europe PMC104
2021 Small, A. G., Harvey, S., Kaur, J., Putty, T., Quach, A., Munawara, U., . . . Ferrante, A. (2021). Vitamin D upregulates the macrophage complement receptor immunoglobulin in innate immunity to microbial pathogens. Communications Biology, 4(1), 401-1-401-7.
DOI Scopus44 WoS37 Europe PMC36
2021 Perveen, K., Quach, A., McPhee, A., Prescott, S. L., Barry, S. C., Hii, C. S., & Ferrante, A. (2021). Cord blood T cells expressing high and low PKCζ levels develop into cells with a propensity to display Th1 and Th9 cytokine profiles, respectively. International Journal of Molecular Sciences, 22(9), 1-16.
DOI Scopus9 WoS9 Europe PMC8
2021 Perveen, K., Quach, A., Stark, M. J., Prescott, S. L., Barry, S. C., Hii, C. S., & Ferrante, A. (2021). Characterization of the transient deficiency of PKC isozyme levels in immature cord blood T cells and its connection to anti-allergic cytokine profiles of the matured cells. International Journal of Molecular Sciences, 22(23), 12650-1-12650-16.
DOI Scopus10 WoS9 Europe PMC8
2020 Krummenacher, M., Perveen, K., Ferrante, A., & Hissaria, P. (2020). The lymphocyte transformation test, flow cytometry and HLA typing in vancomycin induced dress: A case series from South Australia. Pathology, 52, S42.
DOI
2019 Perveen, K., Quach, A., McPhee, A., Prescott, S. L., Barry, S. C., Hii, C. S., & Ferrante, A. (2019). Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells. Scientific reports, 9(1), 9263-1-9263-11.
DOI Scopus9 WoS8 Europe PMC9
2019 Munawara, U., Perveen, K., Small, A. G., Putty, T., Quach, A., Gorgani, N. N., . . . Ferrante, A. (2019). Human dendritic cells express the complement receptor immunoglobulin which regulates T cell responses. Frontiers in Immunology, 10, 2892-1-2892-14.
DOI Scopus16 WoS12 Europe PMC13
2014 Hasan, B., Perveen, K., Olsen, B., & Zahra, R. (2014). Emergence of carbapenem-resistant Acinetobacter baumannii in hospitals in Pakistan. Journal of Medical Microbiology, 63(1), 50-55.
DOI Scopus70 WoS70 Europe PMC52
2010 Zaidi, G., Idrees, M., Malik, F. A., Amin, I., Shahid, M., Younas, S., . . . Parveen, K. (2010). Prevalence of hepatitis delta virus infection among hepatitis b virus surface antigen positive patients circulating in the largest province of pakistan. Virology Journal, 7(1), 5 pages.
DOI Scopus24 WoS16 Europe PMC13

2025

CI as ECR for the RRI STEP Research Funding: Identifying the Best Time to Guide Newborns' Immune Development to Prevent Allergies ($40,000)

2025

Shortlisted – Early Career Research Award, Biochemical Society (2026).

2024

CI as ECR for the SPARK Research Seed Funding Program, Women's and Children's Health Network and The Hospital Research Foundation Group. Study title: Evaluating the critical period for reprogramming T cell development to prevent allergy”. ($50,000) 

2024

Co-CI SA-Pathology Small Grants Scheme – Research ($10,000)

2024

Women's Initiative Award, Australian and New Zealand Society for Immunology. ($1000)

2022

Co-CI Invest for Success grant, Robinson Research Institute, The University of Adelaide. Salary and research support for 6 months. ($30000)

2021

Conference presentation support from the Australian and New Zealand Society for Immunology for online presentation on the 8th Congress of the Federation of Immunological Societies of Asia Oceania (60 USD)

2021

Research Training Program (RTP) Scholarship, Department of Education, Australian Government

2016

Adelaide Scholarships International, 2016-2020, University of Adelaide

2010

Indigenous 5000 PhD Fellowships Scheme, Higher Education Commission, Pakistan

Date Role Research Topic Program Degree Type Student Load Student Name
2024 Co-Supervisor Innate phagocytosis from a basic feeding behaviour to a regulated defence action Doctor of Philosophy Doctorate Full Time Mr Wei Da Ho
2024 Co-Supervisor Early diagnosis of allergy risk and supplement induced immune alterations to prevent allergy Doctor of Philosophy Doctorate Full Time Mr Cameron Damien Skurray
2024 Co-Supervisor Early diagnosis of allergy risk and supplement induced immune alterations to prevent allergy Doctor of Philosophy Doctorate Full Time Mr Cameron Damien Skurray
2024 Co-Supervisor Innate phagocytosis from a basic feeding behaviour to a regulated defence action Doctor of Philosophy Doctorate Full Time Mr Wei Da Ho

Connect With Me

External Profiles

Other Links