Dr Johnny Licari

Grant-Funded Postdoctoral Research Fellow

School of Medicine

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Date Position Institution name
2018 - ongoing Research Fellow University of Adelaide
2017 - 2018 Senior Researcher Bionomics (Australia)

Language Competency
Italian Can read, write, speak and understand spoken

Date Institution name Country Title
University of Adelaide Australia PhD

Year Citation
2023 Dhakal, B., Li, C. M. Y., Ramezanpour, M., Houtak, G., Li, R., Bouras, G., . . . Fenix, K. (2023). Proteomic characterisation of perhexiline treatment on THP-1 M1 macrophage differentiation. Frontiers in Immunology, 14, 13 pages.
DOI Scopus3 WoS3 Europe PMC3
2022 Dhakal, B., Li, C. M. Y., Li, R., Yeo, K., Wright, J. A., Gieniec, K. A., . . . Fenix, K. (2022). The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing. Cancers, 14(4), 16 pages.
DOI Scopus13 WoS14 Europe PMC13
2018 Surikow, S. Y., Nguyen, T. H., Stafford, I., Chapman, M., Chacko, S., Singh, K., . . . Horowitz, J. D. (2018). Nitrosative stress as a modulator of inflammatory change in a model of Takotsubo syndrome. JACC: Basic to Translational Science, 3(2), 213-226.
DOI Scopus60 WoS58 Europe PMC41
2018 Licari, G., Milne, R., Somogyi, A., & Sallustio, B. (2018). Enantioselectivity in the tissue distribution of perhexiline contributes to different effects on hepatic histology and peripheral neural function in rats. Pharmacology Research and Perspectives, 6(3), e00406.
DOI Scopus3 WoS3 Europe PMC3
2017 Panagopoulos, V., Leach, D., Zinonos, I., Ponomarev, V., Licari, G., Liapis, V., . . . Evdokiou, A. (2017). Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment. International Journal of Oncology, 50(4), 1191-1200.
DOI Scopus50 WoS46 Europe PMC50
2015 Chong, C., Drury, N., Licari, G., Frenneaux, M., Horowitz, J., Pagano, D., & Sallustio, B. (2015). Stereoselective handling of perhexiline: implications regarding accumulation within the human myocardium. European Journal of Clinical Pharmacology, 71(12), 1485-1491.
DOI Scopus11 WoS9 Europe PMC7
2015 Licari, G., Somogyi, A., Milne, R., & Sallustio, B. (2015). Comparison of CYP2D metabolism and hepatotoxicity of the myocardial metabolic agent perhexiline in Sprague-Dawley and Dark Agouti rats. Xenobiotica, 45(1), 3-9.
DOI Scopus3 WoS3 Europe PMC1
2015 Chong, C., Liu, S., Licari, G., Heresztyn, T., Chirkov, Y., Ngo, D., & Horowitz, J. (2015). Reversal of hyperglycemia: effects on nitric oxide signaling. American Journal of Medicine, 128(4), 427-430.
DOI Scopus6 WoS6 Europe PMC5
2015 Liu, S., Ngo, D., Chong, C., Amarasekera, A., Procter, N., Licari, G., . . . Horowitz, J. (2015). Suppression of neutrophil superoxide generation by BNP is attenuated in acute heart failure: a case for 'BNP resistance'. European Journal of Heart Failure, 17(5), 475-483.
DOI Scopus15 WoS14 Europe PMC13
2015 Westley, I., Licari, G., & Sallustio, B. (2015). Validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of perhexiline and cis-hydroxy-perhexiline plasma concentrations. Therapeutic Drug Monitoring, 37(6), 821-826.
DOI Scopus2 WoS1 Europe PMC2
2015 Surikow, S., Raman, B., Licari, J., Singh, K., Nguyen, T., & Horowitz, J. (2015). Evidence of nitrosative stress within hearts of patients dying of Tako-tsubo cardiomyopathy. International Journal of Cardiology, 189(1), 112-114.
DOI Scopus28 WoS30 Europe PMC26
2014 Drury, N., Licari, G., Chong, C., Howell, N., Frenneaux, M., Horowitz, J., . . . Sallustio, B. (2014). Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake. British Journal of Clinical Pharmacology, 77(5), 789-795.
DOI Scopus9 WoS9 Europe PMC9
2013 Dautov, R., Ngo, D., Licari, G., Liu, S., Sverdlov, A., Ritchie, R., . . . Chirkov, Y. (2013). The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness. Nitric Oxide-Biology and Chemistry, 35, 72-78.
DOI Scopus22 WoS23 Europe PMC15
2011 Licari, G., Somogyi, A. A., Milne, R. W., & Sallustio, B. C. (2011). MYOCARDIAL AND HEPATIC DISPOSITION OF THE ENANTIOMERS OF PERHEXILINE. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 109, 152.

Year Citation
2009 Licari, J., Somogyi, A. A., Pierides, J., & Sallustio, B. C. (2009). Comparison of sprague dawley and dark agouti rats as animal models of perhexiline-induced hepatotoxicity. In DRUG METABOLISM REVIEWS Vol. 41 (pp. 128). Baltimore, MD: TAYLOR & FRANCIS INC.

Year Citation
2013 Chong, C., Liu, S., Licari, G., Chirkov, Y., Ngo, D., & Horowitz, J. (2013). Reversal of acute hyperglycemia restores tissue responsiveness to nitric oxide and improves endothelial progenitor cell function without downregulating platelet thioredoxin interacting protein. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: American Heart Association.
2013 Licari, G., Singh, K., Chong, C., Thanh, N., Chapman, M., Stafford, I., . . . Horowitz, J. (2013). Increased myocardial expression of thioredoxin-interacting protein, and evidence of nitrosative stress in a rat model of Tako-Tsubo Cardiomyopathy. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: Amercian Heart Association.
2013 Horowitz, J., Nguyen, T., Neil, C., Singh, K., Chong, C., Licari, J., & Raman, B. (2013). Stress cardiomyopathy: new clinical and pathogenetic insights. Poster session presented at the meeting of Abstracts of the 10th International Congress on Coronary Artery Disease (ICCAD), as published in Cardiology. Florence, Italy: Karger.
DOI
2012 Liu, S., Ngo, D. T., Chirkov, Y. Y., Sheikh, A. R., Licari, G., Stewart, S., & Horowitz, J. D. (2012). Brain Natriuretic Peptide (BNP) Suppresses Neutrophil Superoxide Release: Attenuation in Patients with Congestive Heart Failure (CHF). Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS.
2012 Westley, I., Bezak, E., Sjostedt, S., Sallustio, B., & Licari, G. (2012). Investigation of the Role of Acid Sphingomyelinase in the Bystander Effects of Breast Cancer Cell Irradiation. Poster session presented at the meeting of EUROPEAN JOURNAL OF CANCER. Barcelona, SPAIN: ELSEVIER SCI LTD.
DOI

Date Role Research Topic Program Degree Type Student Load Student Name
2022 - 2024 Co-Supervisor Liposomal-Based Delivery of Phosphoantigens as Sensitizers for Gamma Delta T Cell Immunotherapy In Breast Cancer Master of Philosophy (Medical Science) Master Full Time Mr Nikolaos Filippatos

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