John Beltrame

Professor John Beltrame

Professor of Medicine - Michell Chair

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Professor John Beltrame is a world-renowned academic cardiologist with active research, clinical and teaching roles. He is the Michell Chair and Discipline of Medicine Lead at the University of Adelaide. He is also the Director of Research for the Central Adelaide Local Health Network, and a Senior Consultant Cardiologist at The Queen Elizabeth Hospital, Royal Adelaide Hospital and Lyell McEwin Hospital.

His expertise and international research reputation focus on the coronary vasomotor disorders, particularly involving large vessel coronary artery spasm and coronary microvascular dysfunction. He has undertaken seminal work in the clinical characterisation of the coronary slow flow phenomenon, vasospastic angina, and MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries). Furthermore, since women are particularly susceptible to coronary microvascular disorders, many of his studies focus on women’s heart disease.

In addition to these coronary disorders, he has a strong interest in value-based healthcare, particularly evaluating the benefit of cardiac treatments on patient outcomes – referred to as PROMs (ie Patient-Related Outcome Measures). This is largely achieved via the CADOSA (Coronary Angiogram Database of South Australia) Registry, which he developed and currently chairs.

The above collaborative studies not only involve local hospitals and institutions but also international institutions in the United States, Sweden, Norway, Japan and New Zealand.

In addition to these research roles, he is an active clinician and undertakes both undergraduate medical course teaching and post-graduate research training.

Prof Beltrame is focused on translational research, an approach that aims to ensure medical research findings are usable and applicable to patients as quickly as possible. This involves a combination of different types of research:

  • Firstly, integrated laboratory and clinical research or ‘bench to beside’ research which includes discoveries generated in the laboratory and then developed in clinical trials.
  • Secondly, exploring ways of applying evidence-based medicine, recommendations or guidelines to clinical practice. This type of research yields knowledge about real-world settings.

Prof Beltrame undertakes basic, clinical and epidemiological studies into cardiovascular disorders with the objective of improving the health of these patients. Currently the group focuses on coronary heart disease and peripheral artery disease, although many principles are applicable to other vascular disorders.

The research group includes both clinicians and medical scientists located at the Basil Hetzel Institute, the University of Adelaide Medical School and the Central Adelaide Local Health Network. The integrative nature of the group provides a unique opportunity to ensure that innovations are translated from bench to bedside to health outcome, as well as the reverse.

The following research projects are available for semester 1 start and mid-year entry may be considered:

Project 1

Title: Coronary Angiogram Database of South Australia (CADOSA): Improving health outcomes in patients undergoing coronary angiography

Description:Coronary angiography is the clinical benchmark technique in the assessment of coronary artery disease with more than 6,000 performed in South Australia each year. Despite its diagnostic benefits in identifying the presence of coronary disease, its benefit to the patient has been less rigorously studied and will be the focus of this project. CADOSA is an internationally renowned clinical registry incorporating global links with organizations including the American College of Cardiology National Cardiovascular Data Registry and the International Consortium of Health Outcomes Measurement (ICHOM).

Projects Available: Honours and HDR

Location: Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital

Special Requirements: DCSI Clearance, Vaccinations 

 

Project 2

Title: Clinical and Vasomotor Studies of Patients with Myocardial Infarction and Non-Obstructive Coronary Arteries (MINOCA)

Description: Approximately 5-10% of patients who experience a myocardial infarct do not have significant coronary artery disease, prompting the clinical question of what is the underlying mechanism? This project will (i) integrate with established registry studies to assess clinical outcomes and health status of MINOCA patients and (2) utilise invasive and non-invasive clinical techniques to elucidate potential mechanisms that may be responsible for the myocardial infarct.

Projects Available: Honours and HDR

Location: Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital

Special Requirements: DCSI Clearance, Vaccinations

  • Appointments

    Date Position Institution name
    2020 - 2021 Interim Department Head, Medical Specialties, Adelaide Medical School University of Adelaide
    2019 - ongoing Lead, Discipline of Medicine, Adelaide Medical School University of Adelaide
    2018 - 2019 Acting Director of Cardiology Queen Elizabeth Hospital
    2017 - ongoing Senior Consultant Cardiologist Royal Adelaide Hospital
    2017 - ongoing Director of Research Central Adelaide Local Health Network
    2012 - ongoing Cardiology Academic Lead, Central Adelaide Local Health Network SA Health
    2010 - ongoing Michell Professor of Medicine University of Adelaide
    2010 - 2019 Deputy Lead, Discipline of Medicine, Adelaide Medical School University of Adelaide
    2009 - 2010 Acting Director of Cardiology Queen Elizabeth Hospital
    2008 - 2010 Associate Professor in Medicine University of Adelaide
    1999 - 2007 Senior Lecturer in Medicine University of Adelaide
    1999 - ongoing Senior Consultant Cardiologist Queen Elizabeth Hospital
    1999 - ongoing Senior Consultant Cardiologist Lyell McEwin Hospital
    1998 - 1999 Interventional Research Fellow Brigham and Women's Hospital
    1998 - 1999 Interventional Research Fellow Brigham and Women's Hospital
    1997 - 1998 Senior Staff Cardiologist North Western Adelaide Health Service
    1995 - 1997 Cardiology Research Fellow Queen Elizabeth Hospital
    1995 - 1997 Visiting Cardiologist Queen Elizabeth Hospital
    1994 - 1994 Cardiology Research Fellow Kyoto University Hospital
    1993 - 1994 Cardiology Research Fellow Universita Cattolica del Sacro Cuore
    1991 - 1992 Physician Advanced Training Queen Elizabeth Hospital
    1987 - 1990 Physician Basic Training Flinders Medical Centre
    1986 - 1986 Internship Flinders Medical Centre
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2020 Recognition Australia’s Leading Cardiology Researcher – ‘Top 66 Health & Medical Researchers’ The Australian Australia -
    2020 Award 2020 Executive Dean’s Award for Research Excellence (Senior Researcher) Faculty of Health and Medical Sciences, University of Adelaide Australia -
    2019 Honour Member of the Order of Australia (AM) Australian Government Australia -
    2016 Award Peer Review Award (Top 1% of Journal Reviewers) Publons United States -
    2010 Fellowship South Australian Cardiovascular Research Development Program Fellowship - - -
    2008 Award Ahrens Group Award for Outstanding Achievements by a Young Heart Foundation Researcher (SA) - - -
    2006 Award Clinical Postdoctoral Research Fellowship Award The National Heart Foundation of Australia - -
    2003 Award Sylvia & Charles Viertel Charitable Foundation Clinical Investigatorship - - -
    1998 Fellowship The CRB Blackburn RACP Overseas Traveling Fellowship - - -
    1998 Fellowship The Servier Cardiovascular and Metabolic Fellowship - - -
    1997 Award Cardiac Society of Australia & New Zealand Ralph Reader Presentation Finalist - - -
    1995 Scholarship NHMRC Medical Postgraduate Research Scholarship - - -
    1993 Scholarship Italian Government Scholarship for Australian Residents - - -
    1993 Fellowship Lions Overseas Traveling Fellowship - - -
  • Education

    Date Institution name Country Title
    2000 University of Adelaide Australia Doctor of Philosophy (Medicine)
    1986 Flinders University Australia Bachelor of Medicine, Bachelor of Surgery
    1981 University of Adelaide Australia Bachelor of Science
  • Postgraduate Training

    Date Title Institution Country
    1998 - 1999 Interventional Research Fellow Harvard University United States
    1994 - 1994 Cardiology Research Fellow Kyoto University Hospital Japan
    1993 - 1994 Cardiology Research Fellow Universita Cattolica del Sacro Cuore Italy
    1992 Fellow Royal Australasian College of Physicians Australia
  • Certifications

    Date Title Institution name Country
    2008 License to Use or Handle Radioactive Substances Government of South Australia -
    2008 Credentialing in Cardiology SA Health -
    1997 Certified Educational Commission for Foreign Medical Graduates Certified -
    1992 General Medicine & Cardiology Medical Board of South Australia -
  • Research Interests

Research Funding
2000 Pathophysiology of the Coronary Slow Flow Phenomenon J Beltrame, Y. Zhang, I. DeLande. Parke Davis/Pfizer CardioVascular Lipid Research Grant  $40,000
2001 Pathophysiology of the Coronary Slow Flow Phenomenon J Beltrame. New Appointment B3 Grant – University of Adelaide $14,000
2002 - 2004 A Placebo-controlled, Randomised, Double-blind, Crossover Study of the Efficacy of Dipyridamole in the Management of Chest Pain Associated with the Coronary Slow Flow Phenomenon J Beltrame. Boehringer-Ingelheim Support Grant for Investigator-initiated Study. $8,000
2003 Endothelim-dependent Vasodilation in the Coronary and Peripheral Microvasculature of Patients with the Coronary Slow Flow Phenomenon S Turner & J. Beltrame. Pfizer CardioVascular Lipid Research Grant. $40,000
2003 Coronary Haemodynamic Effects of Rho-kinase Inhibition in Coronary Slow Flow J Beltrame. Small Grants Scheme – University of Adelaide/Faculty of Health Science. $10,000
2003 Pathophysiology and Management of the Coronary Slow Flow Phenomenon J Beltrame. Sylvia & Charles Viertel Charitable Foundation Clinical Investigatorship. $55,000
2005 - 2006 The Early Use of Verapamil and Nitrates in Acute Myocardial Infarction J Beltrame, D. Chew, L. Mahar, J. Horowitz. National Heart Foundation of Australia Grant-in-Aid. G 04A 1446; $120,000
2006 - 2007 Endothelin in the Pathophysiology of the Coronary Slow Flow Phenomenon J Beltrame & J. Horowitz. National Heart Foundation of Australia Grant-in-Aid. G 05A 2080; $123,000
2006 The Diagnosis and Management of Microspastic Angina J Beltrame. Pfizer Australia Independent Research Grant $145,000
2006 Multisolvent Delivery System for Analysis of ADMA by HPLC J Horowitz & J Beltrame. National Heart Foundation of Australia ‘J’ Trust Fund $23,870
2006 - 2007 Establishing the Safety and Effectiveness of a Diagnostic Therapeutic Trial for Asthma in Community Elderly R Adams, D Wilson, J Beltrame, R Visvanathan. NHMRC Project Grant (#399124; $411,037
2006 Anna-Marie Trimboli Grant J Beltrame. Anna-Marie Trimboli Trust Fund $40,000
2006 Molecular Mechanisms Underlying Contractile Dysfunction in Smooth Muscle DP Wilson, J Beltrame, G Posterino, P Coates, J Horowitz, J Morrison, L MacKensie, G Coulter, D Saint. NHMRC Equipment Grant $52,861
2006 N-Terminal Pro-B-Type Naturetic Peptide in the Coronary Slow Flow Phenomenon J Beltrame Roche Diagnostics $15,000
2006 - 2007 Coronary Artery Disease in general practice (CADENCE) Study J Beltrame Servier Laboratories (Australia) Pty Ltd

$15,000 

 

2006 The Contribution of ET-A/B Receptors to Endothelin-1 Microvascular Hyper-responsiveness in the Coronary Slow Flow Phenomenon J Beltrame Actelion Pharmaceuticals Australia Pty Ltd $15,000
2006 Myograph Microscopy System. J Beltrame & DP Wilson J-Trust Fund, National Heart Foundation of Australia, SA Division $5,000
2006 - 2009

Clinical Postdoctoral Research Fellowship Award

Mechanism and  new therapies of large and small coronary blood vessel spasm

J Beltrame The National Heart Foundation of Australia. PR 05A 2452, $180,000
2008 - 2010 The Clinical Utility of CT Coronary Angiography in the Assessment of Patients with Intermediate Probability of Coronary Artery Disease J Beltrame & R Sebben BUPA Australia $200,000
2008 Insignificant Coronary Artery Disease (ICAD) Survey J Beltrame Bristol-Myers Squibb $70,000
2008 The Rho Kinase pathway: A therapeutic target for microvascular dysfunction J Beltrame & David Wilson The Queen Elizabeth Hospital Research Foundation $75,000
2008 - 2009 The early use of N-AcetylCysteine In Acute Myocardial infarction: The NACIAM Study J Beltrame, J Horowitz, M Arstall, J Selvanaygam National Heart Foundation Grant-in-Aid. G 07A 3109; $128,400
2008 - 2010 Omega-3 fatty acid supplementation for symptoms of depression in cardiovascular disease G Schrader, J Beltrame, P Howe National Heart Foundation of Australia and Beyond Blue $445,000
2009 - 2010 Health, economic, psychological and social benefits of educating carers P Phillips, T Jones, S Eckerman, S Worthley, J Beltrame, D Chew, M Arstall, P Cafarella. Department of Health Strategic Health Research Program HSR 11599: $486,990
2008 - 2009 The Mevalonate and Rho kinase Pathways: Combination Therapy Targeted at the Treatment of Microvascular Dysfunction DP Wilson, J Beltrame, J Horowitz. National Heart Foundation Grant-in-Aid. G 08A 3641; $123,000
2008 - 2009 Tako-Tsubo Cardiomyopathy: pathogenesis and natural history J Horowitz, J Beltrame, J Selvanayagam, M Frenneaux, D Tsikas NHMRC Project Grant #565404; $237,000
2009 - 2014 TQEH Vascular Disease and Therapeutics Research Group: towards improved outcomes for vascular diseases J Horowitz, J Beltrame, R Morris, R Fitridge, C Zeitz, DP Wilson, B Sallustio, Y Chirkov, J Kennedy, P Cowled TQEH Research Foundation Program Grant $1,040,000
2010 - 2012 Endothelin as a Therapeutic Target in Ischaemic Vascular Disorders J Beltrame. South Australian Cardiovascular Research Development Program Fellowship $450,000
2010 Clinical and Biological Determinants of the Coronary Slow Flow Phenomenon J Beltrame & T Heresztyn TQEH Research Foundation Small Grant Fund $6,000
2010 Italian Heart QoL Study J Beltrame Italian Community Fundraiser $25,000
2010 Laser Doppler Surface Blood Flow Monitor J Beltrame J-Trust Fund, National Heart Foundation of Australia, SA Division $15,000
2010 - 2012 A Placebo-controlled, Randomised, Double-blind, Crossover Study of the Efficacy of Ivabradine in the Management of Chronic Refractory Angina J Beltrame Servier Laboratories Australia Grant-in-Aid $190,000
2011 - 2014 Chronic Refractory Angina – Defining its Characteristics and Exploring Endothelin Blockade as a New Potential Therapy J Beltrame, S Worthley, D Chew. South Australian Cardiovascular Research Development Program Grant $1,327,652
2012 - 2013 A Randomised Comparison Evaluating the Value of High-sensitivity Troponin in the Efficient Management of Chest Pain Across the Spectrum of Risk for an Acute Coronary Syndrome D Chew, J Beltrame, M Worthley, C Zeitz, P Aylward, S Quinn, C Astley. NHMRC Project Grant #1024008; $496,904
2012 Nucleofector for Cell Transfection P Zalewski, JF Beltrame, M Rischmuller. The Hospital Research Foundation Equipment Grant $14,030
2012 Nucleofector for Cell Transfection P Zalewski, JF Beltrame, M Rischmuller University of Adelaide Discipline of Medicine Equipment Grant $10,000
2013 The Coronary Angiogram Database of South Australia (CADOSA) Biobank JF Beltrame, CJ Zeitz, MI Worthley, MA Arstall. University of Adelaide Discipline of Medicine Equipment Grant $10,000
2013 - 2017 The ACCESS Project – Assessment of CAD using Ct Effectively for Stable Symptoms JF Beltrame, CJ Zeitz, R Tavella, MI Worthley. NHMRC Partnership Grant #1062331; $1,564,165
2014 - 2015 Exercise Therapy for the Management of the Coronary Slow Flow Phenomenon JF Beltrame, A Elliott, K Rajopadhyaya, R Fitridge The Hospital Research Foundation $300,000
2015 -2016 CADOSA - Coronary Angiogram Database of South Australia JF Beltrame National Heart Foundation (SA Branch) $993,502
2016 - 2017 Reducing Hospital Variation in Cardiac Device Complications I Ranasinghe, J Beltrame, R Tavella, J Curtis, H Krumholz, S Mazumdar, B Cooper, C Zeitz HCF Research Foundation IRUA2015149; $250,000
2016 - 2018 Ticagrelor In Coronary microvascular dysfunction (TIC) Program – TIC 2: Anti-anginal Efficacy in Primary Coronary Microvascular Disorders JF Beltrame, C Zeitz, M Worthley, M Arstall, R Tavella. AstraZeneca Externally-sponsored Scientific Research ESR-14-10465-TIC 2; $301,710
2016 - 2017 Coronary Haemodynamic Indices – their clinical usefulness for predicting persistent symptoms in patients with chest pain and non-obstructive coronary arteries JF Beltrame The Hospital Research Foundation $100,000
2016 - 2017 Coronary Haemodynamic Indices – their clinical usefulness for predicting persistent symptoms in patients with chest pain and non-obstructive coronary arteries JF Beltrame Northern Communities Health Foundation $30,000
2016 - 2017 Novel Applications of Machine Learning in Healthcare I Ranasinghe, G Carneiro, A van den Hengel, J Beltrame, R Tavella University of Adelaide Interdisciplinary Research Fund 2016 $25,000
2016 Mechanistic Studies of endothelial dependent sex-differences in vascular function JF Beltrame University of Adelaide 2016 School of Medicine Equipment Grant $20,590
2016 Endothelial zinc deficiency as a previously unrecognized factor linked to cigarette smoking and predisposing to vascular endothelial dysfunction and disease

P Zalewski, S Hodge, J Beltrame, C Murgia, R Tavella

University of Adelaide 2016 School of Medicine Near Miss Funding $9,992
2017 EVALuation of Appropriate Use of Elective Percutaneous – VALUE of PCI R Tavella, JF Beltrame, C Zeitz, I Ranasinghe National Heart Foundation Vanguard Grant $75,000
2017 Cardiovascular impacts of obstructive sleep apnoea in men

RJ Adams, SL Appleton, RD McEvoy, J Beltrame

National Heart Foundation Vanguard Grant $75,000
2017 The anti-anginal benefits of Zibotentan in the Coronary Slow Flow Phenomenon JF Beltrame, R Tavella University of Adelaide, Commercial Accelerator Scheme 2016 $87,085
2017 Coronary Angiogram Database of South Australia (CADOSA) Registry JF Beltrame The University of Adelaide Research Infrastructure Scheme $204,000
2017-2020 Potential Mechanisms and Treatment of Post-infarct Angina in Patients with Myocardial Infarction with Non-obstructed Coronary Arteries [MINOCA] JF Beltrame, CJ Zeitz, B Lindahl The Hospital Research Foundation Basil Hetzel Translational Grant $750,000
2017-2020 Potential Mechanisms and Treatment of Post-infarct Angina in Patients with Myocardial Infarction with Non-obstructed Coronary Arteries [MINOCA] JF Beltrame, CJ Zeitz, B Lindahl Centre of Research Excellence in Cardiovascular Outcomes Improvement Grant $62,000
2017 Avanti JE High Speed Centrifuge G Maddern, JF Beltrame, E Gowans, JD Horowitz University of Adelaide, Faculty of Health Science, Research Infrastructure Awards $32,000
2018-2021 Value-based Healthcare in Elective Coronary Stenting JF Beltrame, R Tavella, C Zeitz, J Spertus, M Arstall, M Worthley. D Chew. NHMRC Partnership Grant APP1150036 $2,538, 861
2018-2020 Role for zinc and ZIP2 in the action of nitric oxide and in vascular protection against cigarette smoke and cardiovascular disease P Zalewski, S Hodge, J Beltrame, Chiara Murgia, R Tavella NHMRC Project Grant APP1138917 $685,940
2018-2020 The NALHN Cardiovascular Biobank, revolutionising research in Northern Adelaide

M Arstall, J Beltrame, C Roberts

The Hospital Research Foundation NALHN Grant $100,000
2018 LABS40K Cryogenic Vapour Phase Storage Tank

G Maddern, J Beltrame, P Zalewski, PJ Wormald

University of Adelaide, Research Infrastructure Funding Award $25,538
2018-2019 Biotronik Australia CADOSA Research Grant J Beltrame, R Tavella, C Zeitz, M Worthley   $20,000
2019 Calvary Hospital CADOSA Research Grant J Beltrame, R Tavella   $10,000
2019-2020 Establishing CALHN Clinical Implementation Project Grant Scheme JF Beltrame Health Services Charitable Gift Board Fund $400,000
2019 TQEH Cardiology Research Nurses support JF Beltrame Health Services Charitable Gift Board Fund $173,717
2020-2021 Collaborative depression care for coronary heart disease patients: a clinical trial. ID102973 PJ Tully, JF Beltrame, DP Chew, A Brown. National Heart Foundation Vanguard Grant $150,000
2020-2021 Biotronik Australia CADOSA Research Grant J Beltrame, R Tavella, C Zeitz, M Worthley   $60,000
2020-2022 The Country Heart Attack Prevention (CHAP) Project: A four step model of care and clinical pathway for the translation of cardiac rehabilitation and secondary prevention guidelines into practice for rural and remote patients R Clark, S Nicholls, A Brown, D Chew, J Beltrame, A Maeder, C Maher, V Versace, J Hendriks, P Tideman NHMRC Partnership Grant APP1169893 $1,353,113
2021-2024 The Personalising Acute Myocardial Infarction Care to Improve Outcomes (PAMICO) Project J Beltrame, J Spertus, R Tavella, C Zeitz, G Harvey NHMRC Partnership Grant APP2005797 $3,775,231

Prof Beltrame has successfully supervised numerous research students at Doctoral, Honours, and Undergraduate level.

He has also delivered over 200 formal lectures to Undergraduate Medical Students, Postgraduate General Practitioners, and Postgraduate Physician/Hospital Staff. 

In addition, 14 public lectures have been given over the past 10 years for organizations including TQEH Research Foundation, National Heart Foundation (Federal & South Australian), West Torrens Council, Thebarton Rotary Club, and Prospect Rotary Club.

  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2023 Principal Supervisor Acute Coronary Syndrome in Women Doctor of Philosophy Doctorate Part Time Ms Janet Smith
    2022 Co-Supervisor Effect of aortic valve stenosis on coronary artery blood flow Doctor of Philosophy Doctorate Full Time Ms Tamasin Atkins
    2022 Principal Supervisor Clinical Considerations in Coronary Vasomotor Disorders Doctor of Philosophy Doctorate Full Time Miss Olivia Girolamo
    2022 Co-Supervisor Evaluation of heart transplant transportation device in a pig model Master of Philosophy (Surgery) Master Part Time James Edward Besanko
    2022 Co-Supervisor The challenge of too much and too little vasoconstriction in patient populations: towards improvement in clinical management of cardiac patients with coronary spasm and septic shock patients with vasopressor insensitivity Doctor of Philosophy Doctorate Full Time Miss Anastasia Zacharia
    2021 Principal Supervisor Biological Studies in Coronary Vasomotor Disorders Doctor of Philosophy Doctorate Full Time Mr Alex Minopoulos
    2020 Co-Supervisor Clinical insights into patients with chest pain and NOCA (Non-Obstructive Coronary Arteries) Syndromes Doctor of Philosophy Doctorate Full Time Miss Sarena La
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 - 2022 Principal Supervisor A Journey Through The Thoracic Aorta: From Root To Arch Doctor of Philosophy Doctorate Part Time Dr Timothy Luke Surman
    2018 - 2024 Co-Supervisor Understanding the Longitudinal Characteristics of Chronic Pain in Arthritis:
    The Role of Intensive Longitudinal Methods in Analysing Pain and the Attributable Burden of Persistent Pain on Treatment and Health Outcomes
    Doctor of Philosophy Doctorate Full Time Dr Huai Leng Pisaniello
    2017 - 2022 Co-Supervisor Ischaemia With No Obstructive Coronary Artery Disease (INOCA): Insights Into Assessment and Obstructive Sleep Apnoea Association Doctor of Philosophy Doctorate Full Time Dr Eng Lee Ooi
    2016 - 2020 Principal Supervisor Readmissions in Australian Patients with Cardiovascular Disease Doctor of Philosophy Doctorate Full Time Dr Clementine Labrosciano
    2016 - 2022 Co-Supervisor Incidence, Management, and Outcome of Out-of-Hospital Cardiac Arrest Doctor of Philosophy Doctorate Part Time Mrs Melanie Ruth Wittwer
    2013 - 2017 Principal Supervisor Molecular Mechanisms of Sex-Differences in Vascular Reactivity of Human Internal Mammary Artery Doctor of Philosophy Doctorate Full Time Mr Victor Lamin
    2012 - 2017 Co-Supervisor The Natural History Investigation of In Vivo Human Coronary Endothelial Function and Atheroma Plaque Progression: Invasive Coronary Imaging Studies Doctor of Philosophy Doctorate Full Time Dr Samuel Lengkong Sidharta
    2012 - 2016 Principal Supervisor Novel Clinical Insights into Acute Myocardial Infarction Doctor of Philosophy Doctorate Full Time Dr Sivabaskari Pasupathy
    2011 - 2014 Co-Supervisor Vascular reactivity in sepsis and platelet dysfunction in septic shock Doctor of Philosophy Doctorate Full Time APrf Benjamin John Reddi
    2010 - 2013 Co-Supervisor The Molecular Basis of Small Vessel Constriction in Endothelin-1 Models and Peripheral Arterial Disease Doctor of Philosophy Doctorate Full Time Mrs Kanchani Kitto
    2010 - 2013 Co-Supervisor Regulation of Calcium-Dependent Vasoconstriction in Large and Small Arteries Doctor of Philosophy Doctorate Full Time Miss Yann Yoong Chan
    2010 - 2011 Co-Supervisor Statin mediated vasodilation in the vaculature Doctor of Philosophy Doctorate Full Time Mr Scott Copley
    2010 - 2015 Principal Supervisor Sex-Dependent Differences in Vasomotor Responses of Older Male and Female Humans Doctor of Philosophy Doctorate Full Time Ms Amenah Jaghoori
    2009 - 2014 Co-Supervisor The In Vivo Evaluation of Coronary Atheroma and Endothelium-Dependent Vasomotor Reactivity in Humans with Coronary Artery Disease: Studies Utilizing Intravascular Ultrasound Doctor of Philosophy Doctorate Full Time APrf Rishi Puri
    2009 - 2013 Principal Supervisor Gender Disparities in Vascular Disease Doctor of Philosophy Doctorate Full Time Ms Rachel Dreyer
    2006 - 2012 Principal Supervisor Clinical and Biological Determinants of the Coronary Slow Flow Phenomenon Doctor of Philosophy Doctorate Part Time Miss Victoria Kopetz
    2006 - 2012 Principal Supervisor Health Status Outcomes in Patients Presenting for Coronary Angiography for the Evaluation of Chest Pain Doctor of Philosophy Doctorate Full Time APrf Rosanna Tavella
    2005 - 2010 Principal Supervisor Calcium Channel Distribution in the Arterial Vascular Tree and its Relation to Function Doctor of Philosophy Doctorate Full Time Mrs Christine Smith
    2005 - 2011 Principal Supervisor Clinical Studies of Patients with Acute Coronary Syndromes in the Absence of Obstructive Coronary Artery Disease Doctor of Philosophy Doctorate Part Time Dr Natalie Cutri
    2002 - 2006 Principal Supervisor The Pathophysiology of the Coronary Slow Flow Phenomenon Doctor of Philosophy Doctorate Full Time Dr Stuart Turner
  • Board Memberships

    Date Role Board name Institution name Country
    2020 - ongoing Member Medical Advisory Board INOCA International Australia
    2015 - ongoing Member Board The Hospital Research Foundation Australia
    2013 - ongoing Co-Chair COVADIS (Coronary Vasomotor Disorders International Study group) - -
    2012 - 2016 Chair Year 2 MBBS Board of Examiners University of Adelaide Australia
    2010 - ongoing Member Tom Simpson Trust Fund Board National Heart Foundation of Australia Australia
    2007 - ongoing Board Member The Hospital Research Foundation - Australia
  • Committee Memberships

    Date Role Committee Institution Country
    2021 - ongoing Chair Coronary Vasomotor Dysfunction Working Group Cardiac Society of Australia & New Zealand Australia
    2021 - ongoing Member Women’s Ischemia Trial to Reduce Events in Non-Obstructive Coronary Artery Disease (WARRIOR) Trial External Advisory Panel . Australia
    2021 - ongoing Member International Heart Spasms Alliance Health Professional . Australia
    2020 - ongoing Member Women and Heart Disease Committee National Heart Foundation of Australia Australia
    2020 - 2021 Chair Vanguard Grant Committee National Heart Foundation of Australia Australia
    2020 - ongoing Member Heart Failure Subcommittee South Australian Statewide Cardiology Clinical Network Australia
    2019 - ongoing Chair Strategy and Governance Committee South Australian Cancer Research Biobank (SACRB) Australia
    2019 - ongoing Member Steering Committee South Australian Statewide Cardiology Clinical Network Australia
    2019 - ongoing Member Clinical Trials Flagship Advisory Group Australian Cardiovascular Alliance Australia
    2019 - ongoing Chair Research Week Co-ordinating Committee Central Adelaide Local Health Network Australia
    2019 - ongoing Member Leadership Group Health Analytics Research Collaborative (HARC) Australia
    2019 - ongoing Member Advisory Committee North West Adelaide Health Study (NWAHS) Australia
    2019 - ongoing Member Clinical Quality Registries Framework Review Advisory Group Aust Commission on Safety & Quality in Health Care Australia
    2018 - ongoing Member Scientific Advisory Committee Australian & New Zealand Alliance for Cardiovascular Trials (ANZACT) Australia
    2018 - ongoing Member Steering Committee Australian & New Zealand Alliance for Cardiovascular Trials (ANZACT) Australia
    2018 - ongoing Member Founding Steering Committee National Cardiac Registry Australia
    2018 - ongoing Member PARC Steering Committee Central Adelaide Local Health Network Australia
    2018 - ongoing Member Research Advisory Committee Adelaide BioMed City Australia
    2018 - ongoing Chair Clinical Trials Working Group Adelaide BioMed City Australia
    2017 - ongoing Member PORTRAIT Trial Publication Committee . Australia
    2017 - ongoing Chair Research Executive Committee Central Adelaide Local Health Network Australia
    2017 - ongoing Member Research Directors Committee South Australian Health Australia
    2017 - ongoing Co-Chair MINOCA-BAT Study Steering Group . Australia
    2017 - ongoing Member Research Management Committee South Australian Health Australia
    2017 - ongoing Member New Clinical Procedure Committee Central Adelaide Local Health Network Australia
    2016 - 2019 Member Vanguard Grant Committee National Heart Foundation of Australia Australia
    2016 - ongoing Member Clinical Research Subcommittee South Australian Academic Health Science & Translation Centre Australia
    2016 - ongoing Member Cardiac Rehab Subcommittee South Australian Academic Health Science & Translation Centre Australia
    2015 - ongoing Member Heart & Stroke Leadership Group SA Aboriginal Chronic Disease Consortium Australia
    2015 - ongoing Member Working Group on Quality of Care and Clinical Outcomes European Society of Cardiology France
    2015 - ongoing Member Working Group on Cardiovascular Pharmacology European Society of Cardiology France
    2014 - ongoing Representative South Australian Policy Advisory Committee on Technology (SAPACT) - Cardiology Representative South Australia (SA) Department for Health and Wellbeing Australia
    2013 - ongoing Member Steering Committee Asia Pacific Evaluation of Cardiovascular Therapies (ASPECT) Australia
    2013 - ongoing Member Cardiology Executive Committee Central Adelaide Local Health Network Australia
    2011 - ongoing Member Strategic Research Directions Committee The Basil Hetzel Institute Australia
    2011 - ongoing Chair Steering Committee Coronary Angiogram Database of South Australia (CADOSA) Australia
    2010 - ongoing Member Policy Committee The Basil Hetzel Institute Australia
    2010 - ongoing Member Scholarship Selection Committee The Basil Hetzel Institute Australia
    2008 - ongoing Chair Small Grants Committee The Queen Elizabeth Hospital Research Foundation Australia
    2007 - ongoing Chair South Australian Cardiology Network Data & Information Workgroup Heart Foundation Australia
    2006 - ongoing Member Working Group on Coronary Pathophysiology and Microcirculation European Society of Cardiology France
  • Memberships

    Date Role Membership Country
    2015 - ongoing Member European Society of Cardiology Cardiovascular Pharmacology Working Group -
    2014 - ongoing Member Faculty member of the South Australian Health & Medical Research Institute Australia
    2013 - ongoing Co-Founder Coronary Vasomotion Disorders International Study (COVADIS) Group Australia
    2012 - ongoing - Fellow of the American Heart Association -
    2011 - 2013 Member Graduate MD Advisory Reference Group Australia
    2010 - ongoing Member South Australian Cardiovascular Health Research Network Australia
    2009 - ongoing Member American Heart Association -
    2007 - ongoing Member International Society for Heart Research -
    2006 - ongoing Member European Society of Cardiology Coronary Pathophysiology & Microcirculation Working Group -
    2005 - ongoing - Fellow of the Cardiac Society of Australia and New Zealand -
    2004 - ongoing Member American College of Cardiology United States
    2003 - ongoing Member European Society of Cardiology -
    1998 - 1999 Member The Massachusetts Medical Society United States
    1995 - ongoing Member The Queen Elizabeth Hospital Medical Staff Society Australia
    1992 - ongoing Member Royal Australasian College of Physicians Australia
    1992 - ongoing Member Cardiac Society of Australia & New Zealand Australia
    1992 - ongoing - South Australian Italian Medical Association -
  • Consulting/Advisories

    Date Institution Department Organisation Type Country
    2015 - ongoing Central Adelaide Local Health Network (CALHN) CALHN Strategic Review of Research Health services and related Australia
    2008 - ongoing Schering-Plough Hypertension Advisory Board - - -
    2004 - ongoing Olmetec Advisory Board - - -
    2003 - ongoing Bayer Major Trials Discussion Group - - -
    2002 - ongoing Zanidip State Advisory Group - - -
    2002 - ongoing Teverten Advisory Board - - -
    2002 - ongoing Isocover Advisory Board - - -
    2002 - ongoing Norvasc and Calcium Channel Blocker Workshop Committee - - -
    2001 - ongoing Accupril Strategic Working Group - - -
  • Editorial Boards

    Date Role Editorial Board Name Institution Country
    2016 - ongoing Board Member International Journal of Cardiology - -
    2015 - ongoing Board Member Cardiovascular Innovations and Applications Great Wall International Congress of Cardiology China
    2015 - ongoing Board Member European Heart Journal: Quality of Care and Clinical Outcomes Editorial Board - -
    2014 - ongoing Board Member Coronary Artery Disease Editorial Board - -
    2014 - ongoing Board Member European Heart Journal: Cardiovascular Pharmacotherapy Editorial Board - -
    2014 - ongoing Editor Frontiers in Cardiovascular Medicine, Coronary Cardiology Section - -
    2014 - ongoing Board Member European Cardiology Review Editorial Board - -
    2014 - ongoing Board Member European Heart Journal Cardiovascular Pharmacotherapy European Society of Cardiology -
    2014 - ongoing Board Member European Heart Journal Quality of Care and Clinical Outcomes European Society of Cardiology -
    2014 - ongoing Board Member Coronary Artery Disease - -
    2014 - ongoing Board Member Frontiers in Cardiovascular Medicine, Coronary Vascular Medicine - -
    2013 - ongoing Member Datasets in Science - -
    2012 - ongoing Board Member ISRN Cardiology Editorial Board - -
    2011 - ongoing Board Member World Journal of Hypertension Editorial Board - -
    2011 - ongoing Associate Editor Heart, Lung Circulation - -
    2011 - ongoing Board Member World Journal of Hypertension - -
    2011 - 2015 Associate Editor Heart, Lung & Circulation Cardiac Society of Australia & New Zealand -
    2009 - ongoing Member American College of Physicians PIER (Physicians’ Information & Education Resource) - -
    2008 - ongoing Board Member Heart and Blood Vessels Editorial Board - -
    2008 - ongoing Board Member Heart and Vessels: an international journal - Japan
    2005 - ongoing Board Member Cardiology News Editorial Advisory Board - -
    2005 - ongoing Board Member Virtual Cardiac Centre Editorial Board - -
  • Position: Professor of Medicine - Michell Chair
  • Phone: 82226740
  • Email: john.beltrame@adelaide.edu.au
  • Fax: 82226042
  • Campus: The Queen Elizabeth Hospital
  • Building: QEH - Main Bldg, floor 5
  • Org Unit: Medical Studies

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