
Sarena La
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Sarena recently completed her PhD with the Translational Vascular Function Research Collaborative at the University of Adelaide, Basil Hetzel Institute & The Queen Elizabeth Hospital, and awarded the Deans Commendation for Doctoral Thesis Excellence. She is currently continuing her research as a cardiovascular researcher with CALHN. Sarena's interest and expertise lies in patients with the NOCA (Non-Obstructive Coronary Arteries) Syndrome, with special interest in health outcomes and patient advocacy.
What are the NOCA Syndromes?
Angina is the term used for chest pain or discomfort due to myocardial ischaemia (inadequate supply of blood and oxygen to the myocardium). This usually arises from build up of plaque (atherosclerosis) in the coronary arteries which results in a demand-supply mismatch of oxygen. Those with atherosclerotic blockages are diagnosed with coronary artery disease (CAD), which is the leading cause of death globally.
However, the term NOCA Syndrome describes patients with chest pain but non-obstructive coronary arteries. These disorders include the chronic form ANOCA (Angina with Non-Obstructive Coronary Arteries) and the acute form MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries). The chest pain these patients experience still arises from myocardial ischaemia, but from conditions other than CAD, such as coronary vasomotor disorders (i.e. vasospastic angina or coronary microvascular dysfunction). Due to the absence of CAD, those with NOCA are often overlooked clinically and are often discharged with 'non-cardiac chest pain' despite the possibility of having underlying coronary vasomotor disorders. This issue can be seen around the world, as reflected by the International Heart Spasms Alliance which is a global NOCA patient-led advocacy group.
The NOCA Syndromes may afflict up to 15,000 Australians each year, and although research on this topic has recently gained rapid interest, there remain large gaps in knowledge on these NOCA patients. Our group is recognised as an international leader in this field.
Sarena is available to supervise undergraduate and honours students.
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Appointments
Date Position Institution name 2025 - ongoing Affiliate Lecturer University of Adelaide 2024 - ongoing Cardiovascular Researcher Queen Elizabeth Hospital 2023 - 2023 Teaching and Marking University of Adelaide 2022 - 2022 Conference Coordinator Assistance University of Adelaide 2020 - 2024 Research Data Entry Assistant University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2025 Research Award Deans Commendation for Doctoral Thesis Excellence University of Adelaide Australia - 2023 Award The People's Choice Award South Australian Cardiovascular Research Network Australia - 2023 Research Award New Investigator Poster Prize Cardiac Society of Australia and New Zealand (CSANZ) Australia 500 2022 Research Award South Australian Cardiovascular Showcase Poster Award Heart Foundation Australia 100 2021 Research Award Innovation & Commercial Partners Prize University of Adelaide Australia 100 2020 Award Adelaide Graduate Award University of Adelaide Australia - -
Education
Date Institution name Country Title 2020 - 2024 University of Adelaide Australia PhD (medicine) 2019 - 2020 University of Adelaide Australia Health and Medical Sciences (Honours), First Class 2016 - 2018 University of Adelaide Australia Bachelor of Health and Medical Sciences (Advanced) -
Research Interests
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Journals
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Conference Papers
Year Citation 2024 Girolamo, O., Ismali, M. D., Tavella, R., Ooi, E. L., La, S., Sheikh, A., . . . Beltrame, J. (2024). Coronary slow flow as measured by corrected TIMI frame counts is associated with impaired microvascular resistance. In EUROPEAN HEART JOURNAL Vol. 45 (pp. 1 page). OXFORD UNIV PRESS.
DOI2024 La, S., Tavella, R., Wu, J., Spertus, J., Pasupathy, S., Girolamo, O., . . . Beltrame, J. (2024). Chronic Coronary Syndromes with/without obstructive coronary arteries: are there differences in ongoing chest pain?. In EUROPEAN HEART JOURNAL Vol. 45 (pp. 1 page). OXFORD UNIV PRESS.
DOI2023 La, S., Tavella, R., Wu, J., Girolamo, O., Zeitz, C., Arstall, M., . . . Beltrame, J. (2023). Health outcomes in patients with chronic coronary syndromes due to obstructive or non-obstructive coronary arteries. In EUROPEAN HEART JOURNAL Vol. 44 (pp. 1 page). NETHERLANDS, Amsterdam: OXFORD UNIV PRESS.
DOI2023 La, S., Tavella, R., Wu, J., Zeitz, C., Arstall, M., Sinhal, A., . . . Beltrame, J. (2023). Coronary vasomotor disorders in ANOCA patients: insights from the CADOSA registry. In EUROPEAN HEART JOURNAL Vol. 44 (pp. 1 page). NETHERLANDS, Amsterdam: OXFORD UNIV PRESS.
DOI2023 La, S., Tavella, R., Wu, J., Zeitz, C., Arstall, M., Sinhal, A., . . . Beltrame, J. (2023). Does ischaemia testing predict worse adverse outcomes in ANOCA patients?. In EUROPEAN HEART JOURNAL Vol. 44 (pp. 1 page). NETHERLANDS, Amsterdam: OXFORD UNIV PRESS.
DOI2023 La, S., Tavella, R., Wu, J., Girolamo, O., Zeitz, C., Arstall, M., . . . Beltrame, J. (2023). Health Outcomes in Chronic Coronary Syndromes.. In Heart Lung and Circulation Vol. 32 (pp. S286). Adelaide, Australia: Elsevier.
DOI2023 La, S., Tavella, R., Wu, J., Zeitz, C., Arstall, M., Sinhal, A., . . . Beltrame, J. (2023). Coronary Vasomotor Disorders in ANOCA Patients: Insights From the CADOSA Registry. In Heart, Lung and Circulation Vol. 32 (pp. S277). Elsevier BV.
DOI2023 La, S., Tavella, R., Wu, J., Zeitz, C., Arstall, M., Sinhal, A., . . . Beltrame, J. (2023). Does ischaemia predict worse outcomes in ANOCA patients?. In Heart Lung and Circulation Vol. 32 (pp. S280-S281). Adelaide, Australia: Elsevier.
DOI2023 La, S., Chua, L., Pasupathy, S., Tavella, R., Wu, J., Zeitz, C., . . . Beltrame, J. (2023). Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) Patients
Undergoing Cardiac Magnetic Resonance Imaging (cMRI).. In Heart Lung and Circulation Vol. 32 (pp. S295). Adelaide, Australia: Elsevier.
DOI2022 La, S., Tavella, R., Wu, J., Arstall, M., Sinhal, A., Worthley, M., . . . Beltrame, J. (2022). Diagnostic and therapeutic approach in ANOCA patients: Insights from the CADOSA
registry.. In Heart Lung and Circulation Vol. 31 (pp. S201-S202). Gold Coast, Australia: Elsevier.
DOI2022 La, S., Tavella, R., Wu, J., Arstall, M., Sinhal, A., Worthley, M., . . . Beltrame, J. (2022). ANOCA: An under-recognised and undertreated disorder. Insights from the
CADOSA registry.. In Heart Lung and Circulation Vol. 31 (pp. S193-S194). Gold Coast, Australia: Elsevier.
DOI2022 Ismail, M. D., La, S., Tavella, R., & Beltrame, J. (2022). 10.1016/j.hlc.2022.06.375. In Heart Lung and Circulation Vol. 31 (pp. S226). Gold Coast, Australia: Elsevier.
DOI2022 Ismail, M. D., La, S., Tavella, R., & Beltrame, J. (2022). 10.1016/j.hlc.2022.06.375. In Heart Lung and Circulation Vol. 31 (pp. S226). Gold Coast, Australia: Elsevier.
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Conference Items
Funding Period | Funding Body | Amount | |
Heart Foundation South Australian Travel Grant | 2025 | National Heart Foundation | 4000 |
THRFG/BHI Travel Grant | 2024 | The Hospital Research Foundation Group | 2500 |
University of Adelaide HDR Travel Grant | 2023 | University of Adelaide | 3800 |
THRFG/BHI Travel Grant | 2022 | The Hospital Research Foundation Group | 750 |
EO Myers Trust Fund | 2022 | National Heart Foundation | 2000 |
Research Training Program Scholarship (RTPS) | 2020-2024 | University of Adelaide | |
THRFG Honours Scholarship | 2019 | The Hospital Research Foundation Group | 8000 |
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Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2023 - 2023 Principal Supervisor Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) Patients undergoing Cardiac Magnetic Resonance Imaging (CMR) University of Adelaide Research Placement for Health and Medical Sciences Other Full Time Enna Torres 2023 - 2023 Principal Supervisor Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) Patients undergoing Cardiac Magnetic Resonance Imaging (CMR) University of Adelaide Research Placement for Health and Medical Sciences Other Full Time Madison Liebich 2023 - 2023 Principal Supervisor Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) Patients undergoing Cardiac Magnetic Resonance Imaging (CMR) University of Adelaide Research Placement for Health and Medical Sciences Other Full Time Stephen Hearn 2022 - 2023 Principal Supervisor Predictors and Outcomes of MINOCA diagnosed on Cardiac MRI University of Adelaide Summer Research Project Other Full Time Linnette Chua 2022 - 2023 Co-Supervisor Coronary Artery Spasm Provocation Testing University of Adelaide Summer Research Project Other Full Time Ali Alsharifi
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Committee Memberships
Date Role Committee Institution Country 2025 - ongoing Member TQEH BHI Research Expo Committee Basil Hetzel Institute Australia 2025 - 2025 Member National Allied Health Conference Scientific Committee - Abstract Reviewer National Allied Health Australia 2022 - 2023 Representative Adelaide Medical School/ Biomedicine School HDR Committee University of Adelaide Australia 2022 - ongoing Chair International Heart Spasm Alliance (IHSA) Advisory Committee University of Adelaide Australia 2021 - 2023 Representative Basil Hetzel Institute Management Committee Basil Hetzel Institute Australia 2021 - ongoing Member Coronary Vasomotor Dysfunction Working Group Cardiac Society of Australia & New Zealand Australia -
Memberships
Date Role Membership Country 2023 - ongoing Member European Society of Cardiology (ESC) Belgium 2023 - ongoing Member South Australian Cardiovascular Research Network (SA CVRN) Australia 2021 - ongoing Member Australian Society of Medical Research (ASMR) Australia 2021 - ongoing Member Cardiac Society of Australia and New Zealand (CSANZ) Australia -
Community Engagement
Date Title Engagement Type Institution Country 2022 - 2022 Florey Undergraduate Conference Judge Scientific Community Engagement University of Adelaide Australia 2019 - 2020 Student Representative for Health and Medical Sciences Honours Program Scientific Community Engagement University of Adelaide Australia
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