George Opie

Dr George Opie

NHMRC Early Career Fellow

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


I am an early career neuroscientist located within the neurophysiology of human movement laboratory at The University of Adelaide. My research utilises non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) to mechanistically understand the brain, with a particular emphasis on motor function. Currently, my main research interests revolve around mild forms of traumatic brain injury, with specific focus on identifying how these injuries influence the brain, and how changes within the brain manifest as altered functionality. I'm also interested in understanding how the ageing process influences the brain and in developing interventions for maintaining function in to old age.

Available Research Projects
Neurophysiology of Human Movement Laboratory

Our research utilises non-invasive brain stimulation techniques to investigate neuroplastic changes in synaptic communication, in addition to the function of intracortical circuits, in human volunteers. This enables us to better understand how the brain learns and stores new information, or recovers from injury. These techniques also allow us to design and test the viability of interventions for promoting beneficial changes within the brain in both health and disease. Our research is particularly interested in applying these techniques to better understand changes in the brain associated with mild traumatic brain injury and healthy ageing, in addition to the neurophysiological mechanisms contributing to learning new motor skills.

 

Research Project 1 - Investigating the neurophysiological effects of mild traumatic brain injury

Project description: Mild traumatic brain injury (mTBI) is extremely common, affecting millions of people annually. In contrast to the common belief that these injuries are short-lived in nature, emerging evidence suggests that alterations within the brain may be present long after mTBI. The nature of these alterations, and how they contribute to long-term functional deficits associated with injury, is not well understood. Using advanced non-invasive brain stimulation techniques in conjunction with electroencephalography (EEG), this study will attempt to identify specific mechanisms of brain injury in mTBI patients.

Projects available for: Honours / HDR / Masters
Location: Helen Mayo Building
Research project start: Semester 1 and 2
Special requirements: None

 

Research Project 2 - Cortical mechanisms associated with age-related deficits in motor function

Project description: A degradation of motor function represents one of the most common deficits associated with the ageing process. These changes can impede the ability of older adults to care for themselves, and may significantly reduce their quality of life. Given the rapidly ageing population, it is crucial to develop a better understanding of these deficits and how they might be treated. Subsequently, this project will use advanced non-invasive brain stimulation techniques in conjunction with electroencephalography (EEG) to characterise changes within the brain that may contribute to age-related reductions in motor function.

Projects available for: Honours / HDR / Masters
Location: Helen Mayo Building
Research project start: Semester 1 and 2
Special requirements: None

 

Research Project 3 - Unravelling the role of cerebellar-motor connections in the acquisition of new motor skills.

Project description: Connections between the cerebellum and primary motor cortex are known to be critical mediators of the error-based acquisition of new motor skills. However, the nature of these connections and how they are modulated during learning, remains unclear. Using advanced non-invasive brain stimulation and imaging techniques, the current project aims to develop new measures of cerebellar-motor connectivity that are sensitive to changes associated with the acquisition of novel motor skills.

Projects available for: Honours / HDR / Masters
Location: Helen Mayo Building
Research project start: Semester 1 and 2
Special requirements: None

 

    Expand
  • Appointments

    Date Position Institution name
    2018 NHMRC Early Career Research Fellow University of Adelaide
    2015 - 2018 Research Associate University of Adelaide
    2014 - 2014 Research Assistant University of Adelaide
    2011 - 2013 Research Assistant University of Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2015 Award Deans Commendation for Doctoral Thesis Excellence
    2015 Award Doctoral Research Medal The University of Adelaide Australia
    2014 Award School of Medical Science Travel Award (International)
    2013 Award School of Medical Science Travel Award (National)
    2012 Scholarship Australian Postgraduate Award Scholarship (APA)
    2012 Scholarship Adelaide Centre for Neuroscience Research top-up Scholarship
    2012 Award Adelaide Centre for Neuroscience Research poster award
    2011 Achievement University of Adelaide, 1st class honours
  • Education

    Date Institution name Country Title
    2015 University of Adelaide Australia Ph.D (Neurophysiology)
    2011 University of Adelaide Australia B.Hlth.Sc. (Hons)
    2010 University of Adelaide Australia B.Sc. (Biomed Sc)
  • Research Interests

NHMRC Early Career Fellowship: 'Investigating the “Silent Epidemic”: a TMS-EEG study of mild traumatic brain injury.'

Neurosurgical Research Foundation Grant: 'Characterising the neurophysiological effects of concussion using combined TMS-EEG.'

Neurosurgical Research Foundation Grant: 'Developing TMS-EEG indices of functional and physiological deficit following mild traumatic brain injury.'

  • Position: NHMRC Early Career Fellow
  • Phone: 83134157
  • Email: george.opie@adelaide.edu.au
  • Campus: North Terrace
  • Building: Helen Mayo South, floor 4
  • Room: N4 07
  • Org Unit: Adelaide Medical School

Connect With Me
External Profiles