Dr Eric Smith
School of Medicine
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Eric Smith is a Principal Medical Scientist, Team Leader in Oncology, in the Solid Cancer Research Group, Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, and a Visiting Research Fellow in the Faculty of Health and Medical Sciences.He was awarded his PhD, from The University of Adelaide in 2010, for his thesis entitled “Aberrant DNA methylation in oesophageal cancer and Barrett’s oesophagus”. His thesis was composed of eight original research articles published in peer reviewed journals,, for which he received a commendation from the Dean of Graduate Studies.
My research has focused on increasing our understanding of premalignant and malignant diseases of the colorectum, oesophagus, prostate and breast. I have developed and applied novel and cutting-edge molecular and cellular biology techniques to answer clinically relevant questions, expand our knowledge of disease development, progression and treatment response, identify prognostic biomarkers and potential therapeutic targets, with the overall aim of improving healthcare delivery and patient outcomes. I have established and directed a range of research programs requiring the robust validation of a variety of molecular and cellular biology assays. I have researched networks and pathways associated with the regulation of coding and non-coding RNA in disease development and progression, epithelial-to-mesenchymal transition, fibroblast-epithelial cell cross-talk, identification of prognostic factors and novel therapeutic targets. I have evaluated the efficacy of novel drugs using a range of pre-clinical in vitro and in vivo experimental models with clear clinical translation.
Research Project 1
Title: Identification and characterisation of fibroblast subsets using single cell RNA-sequencing to improve outcomes in patients with rectal cancer.
Project description: Preoperative (neoadjuvant) chemoradiotherapy (nCRT) followed by surgery is widely accepted as the standard of care for patients with rectal cancer. However, most will endure nCRT without clear benefit because currently there is no way to predict which patients will respond. Identification of non-responders before treatment would be enormously beneficial. They would not be at risk of the side effects, and surgery or alternative treatments could be undertaken without unnecessary delay. Significantly, an improved understanding of the factors associated with nCRT resistance could lead to identification of novel targets for intervention and suggest new avenues of research.
This project will investigate the role of cancer associated fibroblasts in the response to nCRT using a combination of innovative and emergent methodologies including single cell RNA-sequencing, multicolour fluorescence immunohistochemistry, and a range of fibroblast-cancer cell co-culture experimental models to identify, characterise and validate novel fibroblast subsets.
Projects available for: Honours / HDR / Masters / Mphil
Location: Basil Hetzel Institute/The Queen Elizabeth Hospital
Research project start: Semester 1 and 2
Special requirements: None
| Date | Position | Institution name |
|---|---|---|
| 2021 - ongoing | Principal Medical Scientist | CALHN (TQEH) |
| 2016 - 2018 | Senior Grant Funded Scientist | CALHN (TQEH) |
| 2016 - ongoing | Visiting Research Fellow | University of Adelaide |
| 2010 - 2016 | Senior Research Officer | The University of Adelaide |
| 2009 - 2015 | Casual Lecturer | Flinders University of South Australia |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2019 | Award | AGIGT 2019 Annual Scientific Meeting : Site Scholarship Award | Australasian Gastro-Instetinal Trials Group (AGIGT) | Australia | - |
| 2018 | Award | The Hospital Research Foundation Research Travel Awards 2018 | The Hospital Research Foundation | Australia | - |
| 2010 | Award | Commendation from the Dean of Graduate Studies | University of Adelaide | - | - |
| 2007 | Award | Winner of 2007 inaugural Faculty of Health Science Postgraduate Research Expo Poster Presenter Award | - | - | - |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2010 | University of Adelaide | Australia | Doctor of Philosophy |
| University of Adelaide | Australia | Bachelor of Science | |
| University of South Australia | Australia | Associate Diploma in Medical Laboratory Science | |
| University of South Australia | Australia | Certificate in Medical Laboratory Science |
| Year | Citation |
|---|---|
| 2020 | Mikaeel, R. R., Young, J. P., Smith, E., & Price, T. J. (2020). INCIDENCE AND MORTALITY RATES OF APPENDICEAL NEOPLASMS ARE ON THE RISE IN AUSTRALIA. In GASTROENTEROLOGY Vol. 158 (pp. S1008-S1009). Austin, TX: W B SAUNDERS CO-ELSEVIER INC. |
| 2019 | Young, J. P., Symonds, E. L., Jesudason, D., Poplawski, N., Ruszkiewicz, A., Uylaki, W., . . . Price, T. J. (2019). INCREASED PREVALENCE OF TYPE 2 DIABETES IN YOUNG ONSET COLORECTAL CANCER. In GASTROENTEROLOGY Vol. 156 (pp. S676-S677). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC. DOI |
| 2019 | Mikaeel, R., Symonds, E., Kimber, J., Uylaki, W., Horsnell, M., Rico, G., . . . Price, T. (2019). Personal history of type 2 diabetes is a potential risk marker for colorectal cancer in young people. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 34 (pp. 42). WILEY. |
| 2015 | Smith, E., Palethorpe, H. M., Ruszkiewicz, A., Leach, D., Need, E., & Drew, P. (2015). Sa1924 Androgen Receptor Pathway As a Prognostic Indicator in Esophageal Adenocarcinoma. In Gastroenterology Vol. 148 (pp. S-356). Elsevier BV. DOI |
| 2013 | Swinstead, E. E., Trotta, A. P., Smith, E., Grover, P. K., Need, E. F., & Buchanan, G. (2013). Estrogen signaling promotes effective progesterone receptor engagement with DNA in breast cancer cells. In CANCER RESEARCH Vol. 73 (pp. 1 page). Washington, DC: AMER ASSOC CANCER RESEARCH. DOI |
| 2007 | Smith, E., De Young, N. J., Ruszkiewicz, A., Devitt, P. G., Jamieson, G., & Drew, P. A. (2007). Novel aberrantly methylated genes in esophageal adenocracinoma. In GASTROENTEROLOGY Vol. 132 (pp. A322). DC, Washington: W B SAUNDERS CO-ELSEVIER INC. WoS1 |
| 2007 | Tsunoda, S., Smith, E., De Young, N. J., Tian, Z. -Q., Liu, J. -F., Jamieson, G. G., & Drew, P. A. (2007). Aberrant methylation of follistatin-like 1 (Fstl1) in esophageal squamous cell carcinoma. In GASTROENTEROLOGY Vol. 132 (pp. A636-A637). DC, Washington: W B SAUNDERS CO-ELSEVIER INC. WoS1 |
| 2006 | Smith, E., Caruso, M., Tian, Z. Q., Liu, J. F., Kelly, J. J., Ruszkiewicz, A. R., & Drew, P. A. (2006). No methylation or reduction in the expression of TIMP3 in squamous cell carcinoma of the esophagus from a region of high incidence in China. In Gastroenterology Vol. 130 (pp. A415). Los Angeles CA: WB Saunders. |
| 2006 | Smith, E., Drew, P. A., Abu-Sheineh, A., Tam, W. C., Ruszkiewicz, A. R., Schoeman, M. N., . . . Holloway, R. H. (2006). Suppression of acid reflux with double-dose esomeprazole for 6 months does not alter DNA methylation in patients with Barrett's esophagus. In Gastroenterology Vol. 130 (pp. A265). Los Angeles 2006: WB Saunders. |
| 2006 | Kelly, J. J., Smith, E., Drew, P. A., Phillis, S. R., Ruszkiewicz, A. R., & Jamieson, G. G. (2006). DNA methylation in the esophageal mucosa of patients 5 or more years after a fundoplication for Barrett's Esophagus. In Gastroenterology Vol. 130 (pp. A8). Los Angeles CA: WB Saunders. |
| 2006 | Smith, E., Nancarrow, D. J., Pavey, S., Hayward, N. K., de Young, N. J., Kelly, J. J., . . . Drew, P. A. (2006). Gene promoter methylation of ID4 and ARL4D in Barrett's esophagus and esophageal adenocarcinoma. In GASTROENTEROLOGY Vol. 130 (pp. A565). CA, Los Angeles: W B SAUNDERS CO-ELSEVIER INC. WoS1 |
| 1995 | Drew, P., Smith, E., Devitt, P., & Thomas, P. (1995). Cerebral arterial fat embolism: a rat model. In Australian and New Zealand Journal of Surgery Vol. 65. Sydney: Wiley. |
| 1994 | Drew, P., Smith, E., Dillon, T., Thomas, P., McLennan, G., & Faris, I. (1994). Neutrophil and mononuclear cell activity in ARDS. In Intensive Care Medicine Vol. 20. Munich. |
| 1993 | Smith, E., Drew, P., Thomas, P., Dillon, T., MacLennan, G., & Faris, I. (1993). Neutrophil degranulation in patients at risk of ARDS. In Anaesthesia and Intensive Care Vol. 22 (pp. 226). Perth. |
| Year | Citation |
|---|---|
| 2020 | Nakhjavani, M., Smith, E., Price, T., Townsend, A., & Hardingham, J. (2020). PS11-38. Ginsenoside Rg3 enantiomers in a defined ratio as a novel treatment for metastatic triple-negative breast cancer. Poster session presented at the meeting of San Antonio Breast Cancer Symposium. San Antonio, TX U.S.A.. |
| 2019 | Smith, E., Tomita, Y., Palethorpe, H., Howell, S., Nakhjavani, M., Townsend, A., . . . Hardingham, J. (2019). Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation and improved overall survival. Poster session presented at the meeting of 31st Lorne Cancer Conference. Lorne, VIC, Australia. |
| 2018 | Palethorpe, H. M., Tomita, Y., Smith, E., Townsend, A. R., Price, T. J., Yool, A. J., & Hardingham, J. E. (2018). Bacopaside II reduces endothelial cell migration and angiogenesis in vitro. Poster session presented at the meeting of 30th Lorne Cancer Conference. Lorne. |
| 2018 | Smith, E., Palethorpe, H. M., Tomita, Y., Townsend, A. R., Price, T. J., Yool, A. J., & Hardingham, J. E. (2018). Anti-tumour effects of Bacopaside II on colorectal cancer cells in vitro. Poster session presented at the meeting of 30th Lorne Cancer Conference. Lorne, VIC. |
| 2017 | Palethorpe, H. M., Smith, E., & Drew, P. A. (2017). New roles for myofibroblasts in cancer - insights from two cancers. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day. |
| 2016 | Palethorpe, H. M., Smith, E., & Drew, P. A. (2016). The effect of fibroblasts on androgen signalling in oesophageal adenocarcinoma cell lines in vitro. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day. |
| 2016 | Palethorpe, H. M., Smith, E., & Drew, P. A. (2016). The effect of fibroblasts on androgen signalling in oesophageal adenocarcinoma cell lines in vitro. Poster session presented at the meeting of 10th Florey International Postgraduate Research Conference. The University of Adelaide. |
| 2015 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2015). Myofibroblast androgen receptor expression modifies direct and indirect interactions between myofibroblasts and prostate cancer cells in vitro. Poster session presented at the meeting of 9th Florey International Postgraduate Research Conference 2015. Adelaide SA. |
| 2015 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2015). Myofiboblast androgen receptor expression modifies direct and indirect interactions between myofibroblasts and prostate cancer cells in vitro. Poster session presented at the meeting of South Australian Men’s Health Research Symposium. South Australian Health and Medical Research Institute (SAHMRI), Adelaide SA. |
| 2015 | Smith, E., Palethorpe, H., Ruszkiewicz, A., Edwards, S., Leach, D., Underwood, T., . . . Drew, P. (2015). Expression of androgen receptor and the androgen-responsive gene FKBP5 are independent prognostic indicators for oesophageal adenocarcinoma. Poster session presented at the meeting of Abstracts of the South Australian Men’s Health Research Symposium. South Australian Health and Medical Research Institute (SAHMRI), Adelaide SA: The University of Adelaide. |
| 2015 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2015). Myofiboblast androgen receptor expression modifies indirect and direct interactions between myofibroblasts and prostate cancer cells in vitro. Poster session presented at the meeting of ASMR SA Annual Scientific Meeting. Adelaide SA. |
| 2014 | Smith, E., Palethorpe, H. M., Ruszkiewicz, A. R., Leach, D. A., Need, E. F., & Drew, P. A. (2014). Expression of androgen receptor and the androgen receptor responsive gene FKBP5 in oesophageal adenocarcinoma. Poster session presented at the meeting of 7th Australian Health & Medical Research Congress 2014. Melbourne Convention and Exhibition Centre, Melbourne, Victoria. |
| 2014 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2014). Myofibroblast androgen receptor expression regulates direct and indirect interactions between myofibroblast and prostate cancer cells in vitro. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2014. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2014 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2014). Myofibroblast androgen receptor expression regulates direct and indirect interactions between myofibroblast and prostate cancer cells in vitro. Poster session presented at the meeting of Florey International Postgraduate Research Conference 2014. |
| 2014 | Palethorpe, H. M., Leach, D. A., Need, E. F., Drew, P. A., & Smith, E. (2014). The effect of androgen receptor expression in fibroblasts co-cultured with prostate cancer cells. Poster session presented at the meeting of ASMR SA Annual Scientific Meeting. Adelaide SA. |
| 2012 | Swinstead, E. E., Trotta, A. P., Smith, E., Grover, P. K., Need, E. F., & Buchanan, G. (2012). The genomic action of progesterone receptor in breast cancer cells requires E2 priming. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2012. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2012 | Giorgio, L., Leach, D. A., Smith, E., Drew, P. A., Trotta, A. P., & Buchanan, G. (2012). Curcumin inhibits cell growth and androgen receptor function in prostate tumour and fibroblast cell lines. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2012. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2011 | Giorgio, L., Harris, T., Drew, P. A., Smith, E., & Buchanan, G. (2011). Exploring the interaction between tumour cells and fibroblasts in prostate cancer. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2011. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2011 | Swinstead, E. E., Need, E. F., Smith, E., & Buchanan, G. (2011). Progesterone receptor signalling in breast cancer cellular processes. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2012. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2011 | Leach, D. A., Drew, P. A., Smith, E., Need, E. F., & Buchanan, G. (2011). Androgen signalling in prostate cancer stroma. Poster session presented at the meeting of The Queen Elizabeth Hospital Research Day 2011. Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA. |
| 2011 | Swinstead, E. E., Need, E. F., Smith, E., & Buchanan, G. (2011). Progesterone receptors in Breast cancer cellular processes. Poster session presented at the meeting of Faculty of Health Sciences Postgraduate Research Conference. |
| 2000 | Smith, E., De Young, N. J., & Drew, P. A. (2000). Phagocytic potential of cells from splenic autotransplants in vitro. Poster session presented at the meeting of . Australasian Society for Immunology 30th Annual Scientific Meeting. |
| 1996 | Smith, E., Drew, P. A., & Thomas, P. D. (1996). Blood brain barrier damage in a rat model of cerebral arterial fat embolism. Poster session presented at the meeting of The Federation of Immunological Societies of Asia Oceania, First Congress. |
| 1995 | Drew, P. A., Smith, E., Thomas, P. D., & Devitt, P. G. (1995). Cerebral arterial fat embolism in the rat. Poster session presented at the meeting of Australian and New Zealand Microcirculation Society Eighth Symposium. |
| Year | Citation |
|---|---|
| 2020 | Hauben, E., Ngo, D., Smith, E., Kirana, C., & Maddern, G. (2020). AU2020903281, Marker associated with colorectal cancer.. Australia. |
| Year | Citation |
|---|---|
| 2010 | Smith, E. (2010). Aberrant DNA methylation in oesophageal cancer and Barrett’s oesophagus. (PhD Thesis, The University of Adelaide). |
| Year | Citation |
|---|---|
| 2025 | Rad, S. K., Yeo, K., Wu, F., Li, R., Nourmohammadi, S., Tomita, Y., . . . Smith, E. (2025). Systematic Review and Meta-Analysis of 16S rRNA and Cancer Microbiome Atlas Datasets to Characterize Microbiota Signatures in Normal Breast, Mastitis and Breast Cancer. DOI |
| 2025 | Kianpour Rad, S., Li, R., Yeo, K., Wu, F., Tomita, Y., Price, T., . . . Smith, E. (2025). Bacterial Infection and Their Cell Wall Ligands Differentially Modulate Doxorubicin Sensitivity in Triple‐Negative Breast Cancer Cells. DOI |
| 2025 | Rad, S. K., Li, R., Yeo, K., Cooksley, C., Shaghayegh, G., Vreugde, S., . . . Smith, E. (2025). Cell Line-Dependent Internalization, Persistence, and Immunomodulatory Effects of Staphylococcus aureus in Triple-Negative Breast Cancer. DOI |
| 2024 | Rad, S. K., Yeo, K., Li, R., Wu, F., Liu, S., Nourmohammadi, S., . . . Smith, E. (2024). Enhancement of Doxorubicin Efficacy by Bacopaside II in Triple-Negative Breast Cancer Cells. DOI |
| 2024 | Heydarlou, H., Hodson, L., Dorraki, M., Hickey, T., Tilley, W., Smith, E., . . . Farajpour, A. (2024). A Deep Learning Approach for Classification of Fibroglandular Breast Density in Histology Images of Human Breast Tissue. DOI |
| 2024 | Yeo, K., Wu, F., Li, R., Smith, E., Wormald, P. -J., Valentine, R., . . . Fenix, K. (2024). Is Short-Read 16S rRNA Sequencing of Oral Microbiome Sampling a Suitable Diagnostic Tool for Head and Neck Cancer?. DOI |
| 2024 | Li, R., Liu, S., Yeo, K., Edwards, S., Li, M. Y., Santos, R., . . . Smith, E. (2024). Circulating SFRP5 levels are elevated in colorectal cancer and correlate with overall survival in stage II-III disease. DOI |
AusHealth Research Funding
Validation of circulating SFRP5 as biomarker for early detection and prognosis of progression in colorectal cancer patients.
Price TJ, Hauben E, Smith E.
$150,000, 2021.
Cancer Council SA (APP1138776)
Personal and family history of type 2 diabetes and risk for colorectal cancer in young adults
Chief investigators: Young J, Price T, Tomlinson I, Rosty C, Ruszkiewicz A, Schrieber A, Platell C, Hardingham J, Smith E, Drew P.
$75,000, 2018.
The Hospital Research Foundation
Paracrine and juxtacrine signalling between prostate cancer cells and fibroblasts
Chief Investigators: Smith E, Drew PA.
$75,000, 2013-2014.
SAHMRI (APP1031549)
Oesophageal adenocarcinoma from patients with or without Barrett’s oesophagus: different gene expression and DNA methylation profiles, biomarkers for survival and response to treatment, and cancer biology.
Chief Investigators: Drew PA, Underwood TJ, Ruszkiewicz AR, Jamieson GG, Associate Investigators: Smith E, Kelly JJ, Devitt PG, Thompson SK.
$87,500, 2012-2013.
Discipline of Medicine RIGB Equipment Grant
Waterless bead baths for busy Tissue Culture laboratory used in multiple research groups within the Faculty of Health Sciences.
Bray S, Grubor-Bauk B, Trotta A, Smith E.
$6,260, 2012.
Cancer Council SA (APP1005078)
Dissecting out what influences the progression from non-dysplastic Barrett's oesophagus to invasive oesophageal adenocarcinoma.
Chief Investigators: Drew PA, Jamieson GG, Ruszkiewicz AR, Underwood T, Smith E, Kelly JJ.
$86,394, 2010.
Cancer Council SA (NP09565194)
Improving diagnosis and treatment of reflux and cancer of the oesophagus by studying changes in microRNAs.
Chief Investigators: Jamieson GG, Drew PA, Smith E, Ruszkiewicz AR, Kelly JJ, Liu J-F.
$72,250, 2009.
Cancer Council SA (APP453588)
Barrett's oesophagus: insights from and into fundoplication and oesophagectomy.
Chief Investigators: Jamieson GG, Drew PA, Devitt PG, Ruszkiewicz AR, Smith E, Liu J-F, Kelly JJ.
$71,750, 2007.
RAH/IMVS Research Committee Project Grant
The expression of miRNAs in oesophageal disease.
Chief Investigators: Jamieson GG, Devitt PG, Drew PA, Smith E, Kelly JJ, Thompson SK.
$19,720, 2007.
NHMRC Project Grant (APP275504)
Barrett's oesophagus and reflux oesophagitis: efficacy of medical vs surgical management.
Chief Investigators: Watson DI, Drew PA, Ruszkiewicz A, Jamieson GG, Bianco-Miotto T, DJ Hussey, Associate Investigators: Miners J, Hayward N, Smith E.
$500,250, 2004-2006.
RAH/IMVS Research Committee Clinical Project Grant
Application for the purchase of a tissue microarrayer for the construction of tissue microarrays for use in studies into colorectal and oesophageal cancer.
Chief Investigators: Jamieson GG, Ruskiewicz AR, Drew PA, Smith E.
$10,000, 2004.
RAH/IMVS Research Committee Clinical Project Grant
Discovery of new genes important in Barrett's oesophagus and adenocarcinoma of the oesophagus by in vitro demethylation of cell and tissue cultures. Chief Investigators: Bianco-Miotto T, Jamieson GG, Watson DI, Smith E, Drew PA.
$20,000, 2003.
The University of Adelaide Small Research Grants
A novel model for studying the effects of aspirin on proliferation, apoptosis and implantation of tumour cells in vivo. Chief Investigators: Jamieson GG, Watson DI, Drew PA, Smith E.
$7,445, 2001.
The University of Adelaide
2009 Semester 2, Research in Surgery 2920_RSCHMED_8112
2010 Semester 1, Research in Surgery 3010_RSCHMED_8112
2010 Semester 2, Research in Surgery 3020_RSCHMED_8112
2015 Semester 1, Cellular and Systems Neurobiology 3510_PHYSIOL_3001
2015 Semester 2, Integrative and Applied Systems Physiology 3520_PHYSIOL_3000
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2024 | Co-Supervisor | The development of more effective next-generation cytokine-induced killer cell therapies for the improved treatment of metastatic colorectal cancer | Doctor of Philosophy | Doctorate | Full Time | Mrs Elham Shokati |
| 2024 | Co-Supervisor | The development of more effective next-generation cytokine-induced killer cell therapies for the improved treatment of metastatic colorectal cancer | Doctor of Philosophy | Doctorate | Full Time | Mrs Elham Shokati |
| 2023 | Principal Supervisor | Repurposing the anti-anginal drug perhexiline for the treatment of cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Fangmeinuo Wu |
| 2023 | Principal Supervisor | Repurposing the anti-anginal drug perhexiline for the treatment of cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Fangmeinuo Wu |
| 2022 | Principal Supervisor | The Biology of Triple Negative Breast Cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Sima Kianpour Rad |
| 2022 | Principal Supervisor | Over-expression of SFRP5 in hepatocytes: a novel treatment strategy for colorectal cancer liver metastases | Doctor of Philosophy | Doctorate | Full Time | Mr Runhao Li |
| 2022 | Co-Supervisor | The role of TLR4 in mammographic density and breast cancer risk | Doctor of Philosophy | Doctorate | Full Time | Miss Hanieh Heydarlou |
| 2022 | Principal Supervisor | The Biology of Triple Negative Breast Cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Sima Kianpour Rad |
| 2022 | Principal Supervisor | Over-expression of SFRP5 in hepatocytes: a novel treatment strategy for colorectal cancer liver metastases | Doctor of Philosophy | Doctorate | Full Time | Mr Runhao Li |
| 2022 | Co-Supervisor | The role of TLR4 in mammographic density and breast cancer risk | Doctor of Philosophy | Doctorate | Full Time | Miss Hanieh Heydarlou |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2018 - 2022 | Co-Supervisor | Towards an Understanding of the Growing Incidence of Colorectal Cancer and Appendiceal Neoplasms in Young Adults | Doctor of Philosophy | Doctorate | Full Time | Mr Reger Romi Mikaeel |
| 2013 - 2018 | External Supervisor | Fibroblasts, Androgen Signalling and Oesophageal Adenocarcinoma | Doctor of Philosophy | Doctorate | Full Time | Ms Helen Palethorpe |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2019 - ongoing | Principal Supervisor | Is aquaporin 1 expression a poor prognostic marker in colorectal cancer? | The University of Adelaide | - | Honours | Full Time | James Clarke |
| 2019 - ongoing | Co-Supervisor | Identification of microRNA predictive of response to therapeutic agents in colorectal cancer | The University of Adelaide | - | Honours | Full Time | Steven Ha |
| 2019 - ongoing | Co-Supervisor | scRNA Analysis of Tumour Samples | The University of Adelaide | Master of Biotechnology (Biomedical Science) | Master | - | Junwei Wang |
| 2015 - 2015 | Principal Supervisor | Androgen signalling in oesophageal carcinoma | The University of Adelaide | 3rd year research project for 3520_PHYSIOL_3000 and 3510_PHYSIOL_3001 | Other | Part Time | Nathan Borg |
| 2015 - 2015 | Principal Supervisor | Androgen signalling in oesophageal adenocarcinoma | The University of Adelaide | 3rd year research project for 3520_PHYSIOL_3000 and 3510_PHYSIOL_3001 | Other | - | Alice Short |
| 2015 - 2015 | Principal Supervisor | Androgen signalling in oesophageal adenocarcinoma | The University of Adelaide | 3rd year research project for 3520_PHYSIOL_3000 and 3510_PHYSIOL_3001 | Other | Part Time | Alexandra Burdakova |
| 2015 - 2015 | Principal Supervisor | Androgen signalling in oesophageal adenocarcinoma | The University of Adelaide | 3rd year research project for 3520_PHYSIOL_3000 and 3510_PHYSIOL_3001 | Other | Part Time | Yang Hu |
| 2007 - 2007 | Co-Supervisor | Methylation of Wnt pathway genes in oesophageal cancer | The University of Adelaide | - | Honours | Full Time | Karissa Phillis |
| Date | Topic | Location | Name |
|---|---|---|---|
| 2018 - ongoing | Investigation of the Mechanism of Action of a Ginsenoside Compound on Tumour Growth and Angiogenesis in Advanced Breast Cancer | The University of Adelaide | Maryam Nakhjavani |
| 2017 - ongoing | New drug candidates targeting aquaporin 1 show efficacy in reducing colon cancer metastasis in a murine model – pre-clinical work-up for first-in-human trials | The University of Adelaide | Dr Helen Palethorpe |
| 2015 - ongoing | Pharmacological Blocking of Aquaporin 1 to Restrict Tumour Angiogenesis and Metastasis in Pre-Clinical Models of Human Colon Cancer | The University of Adelaide | Dr Yoko Tomita |
| 2015 - ongoing | Does Inhibition of Cation Conductance in Aquaporin-1 Channels Expressed in Tumour Cells Impede Tumour Cell Migration? | The University of Adelaide | Michael Lucio De Ieso |
| 2012 - 2012 | Steroid Receptor Crosstalk in Breast Cancer Cells | The University of Adelaide | Miss Erin Elizabeth Swinstead |
| 2012 - 2012 | Curcumin Action in Prostate Cancer Cells and Fibroblasts | The University of Adelaide | Miss Lauren Giorgio |
| 2010 - 2014 | Androgen signalling in the prostate cancer microenvironment | The University of Adelaide | Damien Alexander Leach |
| 2008 - 2009 | DNA methylation in oesophageal squamous cell carcinoma | The University of Adelaide/Royal Adelaide Hospital | Dr Shigeru Tsunoda |
| 2006 - 2007 | The effect of long-term control of reflux by fundoplication on aberrant deoxyribonucleic acid methylation in patients with Barrett esophagus | The University of Adelaide/Royal Adelaide Hospital | Mr John Jamie Kelly |
| 2004 - 2005 | Aspirin and indomethacin for the prevention of experimental port-site metastases | The University of Adelaide/Royal Adelaide Hospital | Dr Shoichi Kinugasa |
| 2003 - 2004 | DNA methylation in oesophageal squamous cell carcinoma | The University of Adelaide/Royal Adelaide Hospital | Dr Zi-Qiang Tian |
| 2002 - 2003 | Tumor implantation during laparoscopy using different insufflation gases - an experimental study using cultured cancer cells | The University of Adelaide/Royal Adelaide Hospital | Dr Robert Ludemann |
| 1999 - 2000 | Oesophageal cancer | The University of Adelaide | Professor Jun-Feng Liu |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2022 - ongoing | Chair | Research Advisory Committee | Basil Hetzel Institute for Translational Health Research | Australia |
| 2021 - ongoing | Member | Basil Hetzel Institute for Translational Health Research Policy Committee | Basil Hetzel Institute for Translational Health Research | Australia |
| 2020 - ongoing | Chair | The Queen Elizabeth Hospital Institutional Biosafety Committe | The Queen Elizabeth Hospital | Australia |
| 2019 - ongoing | Member | Basil Hetzel Insitute Equipment Prioritisation Subcommittee | Basil Hetzel Insitute | Australia |
| 2015 - 2020 | Member | The Queen Elizabeth Hospital Institutional Biosafety Committee | The Queen Elizabeth Hospital | Australia |
| 2015 - 2012 | Member | Basil Hetzel Institute Management Committee | Basil Hetzel Institute for Translational Health Research | Australia |
| 2012 - 2014 | Member | Women’s and Children’s Hospital Foundation Research Committee | Women’s and Children’s Hospital Foundation | Australia |
| 2012 - ongoing | Member | Basil Hetzel Institute Strategic Directions Committee | Basil Hetzel Institute | Australia |
| 2009 - 2016 | Member | The University of Adelaide Open Day Organisation Committee | The University of Adelaide | Australia |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2018 - ongoing | Member | The Australasian Gastro-Intestinal Cancer Trials Group (AGITG) | Australia |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2016 - ongoing | THRF Community Awareness Program for the Tea Tree Gully Probus Club | Public Community Engagement | The Hospital Research Foundation | Australia |
| 2015 - ongoing | Oesophageal Cancer Awareness | Public Community Engagement | Adelaide’s CoastFM 88.7 | - |
| 2013 - ongoing | Prostate Cancer Awareness | Public Community Engagement | Adelaide’s CoastFM 88.7 | - |
