Prof David Waugh
Dean, Health Innovation, Precincts and Partnerships
Office of Health
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor David Waugh is the Inaugural Pro-Vice Chancellor for Health and Medical Research and Engagement at University of South Australia, a role focused on developing inter-disciplinary and impactful research programmes that provide transformative solutions to inform improved patient outcomes and future healthcare practice. He was formerly the Head of School for Biomedical Sciences at Queensland University of Technology and prior to emigrating to Australia, he served as Director of the Patrick G Johnston Centre for Cancer Research at Queen’s University and the CRUK Belfast Cancer Centre, developing an ecosystem that integrated academic discovery science with entrepreneurial biotech research and development and finally implementation in innovative early-phase clinical trials.
A Professor of Molecular Oncology and Therapeutics, David is an internationally-respected prostate cancer researcher focusing on using scientific discoveries to inform the use of new therapies in treating men with prostate cancer. He was the Founding Director of the FASTMAN Movember/PCUK Centre of Excellence (2013-2018) between Queen’s University Belfast and the University of Manchester in the UK, a programme delivering biomarkers and a series of translational studies to improve the outcomes of prostate cancer patients being treated for high-risk disease using radiotherapy protocols. His own research has focused on disrupting the inflammatory storms driven by chemokine signalling that underpin the aggressive and life-threatening behaviour of specific, genetically-defined subtypes of prostate cancer.
| Year | Citation |
|---|---|
| 2025 | Hindes, M. T., McElligott, A. M., Best, O. G., Ward, M. P., Selemidis, S., Miles, M. A., . . . Brooks, D. A. (2025). Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer. Cancer Letters, 611(217441), 217441-1-217441-18. Scopus13 WoS14 Europe PMC11 |
| 2025 | Grist, E., Dutey-Magni, P., Parry, M. A., Mendes, L., Sachdeva, A., Proudfoot, J. A., . . . Attard, G. (2025). Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers.. Cell, 188(20), 1-29. Scopus11 WoS11 Europe PMC10 |
| 2025 | Lam, G., Martini, C., Sorvina, A., Hickey, S., Hindes, M., Waugh, D., . . . Logan, J. (2025). Implications of Altered Endosomal-Lysosomal Biogenesis in Melanoma Pathogenesis. International Journal of Molecular Sciences, 26(20, article no. 10113), 1-15. |
| 2025 | Bessot, A., Medeiros Savi, F., Gunter, J., Mendhi, J., Amini, S., Waugh, D., . . . Bock, N. (2025). Humanized in vivo bone tissue engineering: in vitro preculture conditions control the structural, cellular, and matrix composition of humanized bone organs. Advanced Healthcare Materials, 14(2, article no. 2401939), 1-22. Scopus5 Europe PMC5 |
| 2025 | Bessot, A., Röhl, J., Emmerich, M., Klotz, A., Ravichandran, A., Meinert, C., . . . Bock, N. (2025). ECM-mimicking hydrogel models of human adipose tissue identify deregulated lipid metabolism in the prostate cancer-adipocyte crosstalk under antiandrogen therapy. Materials Today Bio, 30(101424), 1-17. Scopus5 WoS6 Europe PMC4 |
| 2024 | Nturubika, B. D. D., Logan, J., Johnson, I. R. D., Moore, C., Li, K. L., Tang, J., . . . Brooks, D. A. (2024). Components of the endosome-lysosome vesicular machinery as drivers of the metastatic cascade in prostate cancer. Cancers, 17(1), 1, article no. 43-31. Scopus4 WoS4 Europe PMC4 |
| 2023 | Bessot, A., Gunter, J., Waugh, D., Clements, J. A., Hutmacher, D. W., McGovern, J., & Bock, N. (2023). GelMA and biomimetic culture allow the engineering of mineralized, adipose, and tumor tissue human microenvironments for the study of advanced prostate cancer in vitro and in vivo. Advanced Healthcare Materials, 12(14, article no. 2201701), e2201701. Scopus27 Europe PMC22 |
| 2023 | Guo, C., Sharp, A., Gurel, B., Crespo, M., Waugh, D., & de Bono, J. S. (2023). Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance. Nature, 623(7989), 1053-1061. Scopus85 WoS95 Europe PMC92 |
| 2022 | Waugh, D. J. J., McGovern, J. A., & McCusker, S. (2022). The challenges and emerging opportunities of targeting cytokines and chemokine-driven inflammatory signals in metastatic castrate-resistant prostate cancer.. Critical Reviews in Oncogenesis, 27(1), 25-43. Scopus3 Europe PMC2 |
| 2022 | Mak, B., Lin, H. -M., Kwan, E. M., Fettke, H., Tran, B., Davis, I. D., . . . Horvath, L. G. (2022). Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer. BMC Medicine, 20(1), 112-1-112-14. Scopus19 WoS19 Europe PMC18 |
| 2022 | Maxwell, P. J., McKechnie, M., Armstrong, C. W., Manley, J. M., Ong, C. W., Worthington, J., . . . Waugh, D. J. J. (2022). Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers. Molecular Cancer Research, 20(6), 841-853. Scopus8 Europe PMC7 |
| 2021 | Hanna, C., Dunne, V. L., Walker, S. M., Butterworth, K. T., McCabe, N., Waugh, D. J. J., . . . Prise, K. M. (2021). ATM kinase inhibition preferentially sensitises pten-deficient prostate tumour cells to ionising radiation. Cancers, 13(1, article no. 79), 1-17. Scopus8 |
| 2021 | Amoroso, F., Glass, K., Singh, R., Liberal, F., Steele, R. E., Maguire, S., . . . Mills, I. G. (2021). Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells. Scientific Reports, 11(1, article no. 4252), 1-16. Scopus12 Europe PMC14 |
| 2020 | Murphy, R. G., Roddy, A. C., Srivastava, S., Baena, E., Waugh, D. J., O Sullivan, J. M., . . . LaBonte, M. J. (2020). Prostate cancer heterogeneity assessment with multi-regional sampling and alignment-free methods. NAR Genomics and Bioinformatics, 2(3, article no. lqaa062), 1-7. |
| 2020 | Armstrong, C. W. D., Coulter, J. A., Ong, C. W., Maxwell, P. J., Walker, S., Butterworth, K. T., . . . Waugh, D. J. J. (2020). Clinical and functional characterization of CXCR1/CXCR2 biology in the relapse and radiotherapy resistance of primary PTEN-deficient prostate carcinoma. Nar Cancer, 2(3). Scopus16 |
| 2019 | Gilmore, A. R., Alderdice, M., Savage, K. I., O Reilly, P. G., Roddy, A. C., Dunne, P. D., . . . McArt, D. G. (2019). ACE: A workbench using evolutionary genetic algorithms for analyzing association in TCGA. Cancer Research, 79(8), 2072-2075. Scopus6 Europe PMC5 |
| 2019 | Di Mitri, D., Mirenda, M., Vasilevska, J., Calcinotto, A., Waugh, D., & Alimonti, A. (2019). Re-education of tumor-associated macrophages by CXCR2 blockade drives senescence and tumor inhibition in advanced prostate cancer. Cell Reports, 28(8), 2156.e5-2168.e5. Scopus161 Europe PMC151 |
| 2018 | Jain, S., Lyons, C. A., Walker, S. M., McQuaid, S., & Waugh, D. J. (2018). Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy. Annals of Oncology, 29(1), 215-222. Scopus90 Europe PMC98 |
| 2018 | Ong, C. W., Maxwell, P., Alvi, M. A., McQuaid, S., Waugh, D., Mills, I., & Salto Tellez, M. (2018). A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases. Journal of Pathology: Clinical Research, 4(2), 103-113. Scopus20 Europe PMC21 |
| 2018 | Sumanasuriya, S., Omlin, A., Armstrong, A., Attard, G., Chi, K. N., Bevan, C. L., . . . de Bono, J. S. (2018). Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer. European Urology Oncology, 1(2), 151-159. Scopus30 Europe PMC28 |
| 2018 | McCann, C., Crawford, N., Majkut, J., Holohan, C., Armstrong, C. W. D., Maxwell, P. J., . . . Longley, D. B. (2018). Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists. Cell Death and Disease, 9(11, article no. 1081), 1-13. Scopus13 Europe PMC14 |
| 2017 | Walker, S. M., Knight, L. A., McCavigan, A. M., Logan, G. E., Waugh, D. J., & Kennedy, R. D. (2017). Molecular subgroup of primary prostate cancer presenting with metastatic biology. European Urology, 72(4), 509-518. Scopus29 Europe PMC23 |
| 2017 | Waugh, D. J. J. (2017). Expanding the Armamentarium for Castrate-resistant Prostate Cancer. European Urology, 71(3), 328-329. Scopus1 Europe PMC1 |
| 2016 | Bingham, V., Ong, C. W., James, J., Maxwell, P., Waugh, D., Salto Tellez, M., & McQuaid, S. (2016). PTEN mRNA detection by chromogenic, RNA in situ technologies: a reliable alternative to PTEN immunohistochemistry. Human Pathology, 47(1), 95-103. Scopus18 Europe PMC20 |
| 2016 | Armstrong, C. W. D., Maxwell, P. J., Ong, C. W., Redmond, K. M., McCann, C., Neisen, J., . . . Waugh, D. J. J. (2016). PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy. Oncotarget, 7(7), 7885-7898. Scopus32 Europe PMC29 |
| 2016 | Dunne, P. D., McArt, D. G., Bradley, C. A., O'Reilly, P. G., Barrett, H. L., Cummins, R., . . . Van Schaeybroeck, S. (2016). Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer. Clinical Cancer Research, 22(16), 4095-4104. Scopus129 Europe PMC128 |
| 2016 | Lawler, M., Gavin, A., Salto-Tellez, M., Kennedy, R. D., Van Schaeybroeck, S., Wilson, R. H., . . . Waugh, D. J. (2016). Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program. Cancer, 122(5), 664-673. Scopus6 Europe PMC2 |
| 2015 | Ong, C. W., Chong, P. Y., McArt, D. G., Chan, J. Y., Tan, H. T., Kumar, A. P., . . . Salto Tellez, M. (2015). The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers. Oncotarget, 6(14), 12763-12773. Scopus19 Europe PMC13 |
| 2015 | McFarlane, S., McFarlane, C., Montgomery, N., Hill, A., & Waugh, D. J. J. (2015). CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices. Oncotarget, 6(34), 36762-36773. Scopus58 Europe PMC58 |
| 2015 | McFarlane, S., Coulter, J. A., Tibbits, P., O'Grady, A., McFarlane, C., Montgomery, N., . . . Waugh, D. J. J. (2015). CD44 increases the efficiency of distant metastasis of breast cancer. Oncotarget, 6(13), 11465-11476. Scopus100 Europe PMC90 |
| 2014 | Maxwell, P. J., Neisen, J., Messenger, J., & Waugh, D. J. J. (2014). Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells. Oncotarget, 5(13), 4895-4908. Scopus73 Europe PMC70 |
| 2014 | D'Costa, Z. C., Higgins, C., Ong, C. W., Irwin, G. W., Boyle, D., McArt, D. G., . . . Mullan, P. B. (2014). TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: A novel cancer-selective target pathway with therapeutic opportunities. Oncotarget, 5(6), 1609-1620. Scopus38 Europe PMC34 |
| 2013 | Crawford, N., Stasik, I., Holohan, C., Majkut, J., McGrath, M., Johnston, P. G., . . . Longley, D. B. (2013). SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma. Cell Death and Disease, 4(7), e733. Scopus22 |
| 2013 | Waugh, D. J. J. (2013). Reply from Authors re: Zoran Culig. CXCL8, an underestimated "bad guy" in prostate cancer. Eur Urol 2013;64:189-90: Putting the "bad Guy" CXCL8 into context. European Urology, 64(2), 190-192. |
| 2013 | Campbell, L. M., Maxwell, P. J., & Waugh, D. J. J. (2013). Rationale and means to target pro-inflammatory interleukin-8 (CXCL8) signaling in cancer. Pharmaceuticals, 6(8), 929-959. Scopus125 |
| 2013 | Ray, S., Johnston, R., Campbell, D. C., Nugent, S., McDade, S. S., Waugh, D., & Panov, K. I. (2013). Androgens and estrogens stimulate ribosome biogenesis in prostate and breast cancer cells in receptor dependent manner. Gene, 526(1), 46-53. Scopus25 Europe PMC23 |
| 2013 | Ming, L., Byrne, N. M., Camac, S. N., Mitchell, C. A., Ward, C., Waugh, D. J., . . . Worthington, J. (2013). Androgen deprivation results in time-dependent hypoxia in LNCaP prostate tumours: Informed scheduling of the bioreductive drug AQ4N improves treatment response. International Journal of Cancer, 132(6), 1323-1332. Scopus39 Europe PMC35 |
| 2013 | McCourt, C. M., McArt, D. G., Mills, K., Catherwood, M. A., Maxwell, P., Waugh, D. J., . . . Salto-Tellez, M. (2013). Validation of Next Generation Sequencing Technologies in Comparison to Current Diagnostic Gold Standards for BRAF, EGFR and KRAS Mutational Analysis. Plos One, 8(7), e69604. Scopus107 Europe PMC81 |
| 2013 | Maxwell, P. J., Coulter, J., Walker, S. M., McKechnie, M., Neisen, J., McCabe, N., . . . Waugh, D. J. J. (2013). Potentiation of inflammatory CXCL8 signalling sustains cell survival in pten-deficient prostate carcinoma. European Urology, 64(2), 177-188. Scopus71 Europe PMC66 |
| 2013 | Medina, R. J., O'neill, C. L., O'doherty, T. M., Chambers, S. E. J., Guduric-Fuchs, J., Neisen, J., . . . Stitt, A. W. (2013). Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function. Stem Cells, 31(8), 1657-1668. Scopus61 Europe PMC50 |
| 2012 | Montgomery, N., Hill, A., McFarlane, S., Neisen, J., O'Grady, A., Conlon, S., . . . Waugh, D. J. J. (2012). CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity. Breast Cancer Research, 14(3), R84. Scopus67 Europe PMC58 |
| 2012 | Wilson, C., Maxwell, P. J., Longley, D. B., Wilson, R. H., Johnston, P. G., & Waugh, D. J. J. (2012). Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer. Plos One, 7(5), e36545. Scopus21 Europe PMC18 |
| 2012 | McCourt, C., Maxwell, P., Mazzucchelli, R., Montironi, R., Scarpelli, M., Salto-Tellez, M., . . . Waugh, D. J. J. (2012). Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy. Clinical Cancer Research, 18(14), 3822-3833. Scopus56 Europe PMC52 |
| 2011 | Valentine, A., O'Rourke, M., Yakkundi, A., Worthington, J., Hookham, M., Bicknell, R., . . . Robson, T. (2011). FKBPL and peptide derivatives: Novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism. Clinical Cancer Research, 17(5), 1044-1056. Scopus52 Europe PMC49 |
| 2011 | Oladipo, O., Conlon, S., O'Grady, A., Purcell, C., Wilson, C., Maxwell, P. J., . . . Waugh, D. J. J. (2011). The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. British Journal of Cancer, 104(3), 480-487. Scopus75 Europe PMC64 |
| 2010 | Higgins, C. A., Bell, T., Delbederi, Z., Feutren-Burton, S., McClean, B., O'Dowd, C., . . . Van Den Berg, H. (2010). Growth inhibitory activity of extracted material and isolated compounds from the fruits of Kigelia pinnata. Planta Medica, 76(16), 1840-1846. Scopus31 Europe PMC12 |
| 2009 | Higgins, C. A., Delbederi, Z., McGarel, K., Mills, T., McGrath, O., Feutren-Burton, S., . . . Van Den Berg, H. (2009). Synthesis and in vitro and in vivo evaluation of a series of dihydroisocoumarin derivatives conjugated with fatty acids, alcohols, and amines as potential anticancer agents. Bioconjugate Chemistry, 20(9), 1737-1751. Scopus20 Europe PMC9 |
| 2009 | Seaton, A., Maxwell, P. J., Hill, A., Gallagher, R., Pettigrew, J., Wilson, R. H., & Waugh, D. J. J. (2009). Inhibition of constitutive and cxc-chemokine-induced NF-B activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells. British Journal of Cancer, 101(9), 1620-1629. Scopus13 Europe PMC9 |
| 2008 | Waugh, D. J. J., Wilson, C., Seaton, A., & Maxwell, P. J. (2008). Multi-faceted roles for CXC-chemokines in prostate cancer progression. Frontiers in Bioscience, 13(12), 4595-4604. Scopus54 Europe PMC44 |
| 2008 | Wilson, C., Wilson, T., Johnston, P. G., Longley, D. B., & Waugh, D. J. J. (2008). Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells. Molecular Cancer Therapeutics, 7(9), 2649-2661. Scopus94 Europe PMC78 |
| 2008 | Wilson, C., Purcell, C., Seaton, A., Oladipo, O., Maxwell, P. J., O'Sullivan, J. M., . . . Waugh, D. J. J. (2008). Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-κB transcription and evasion of apoptosis. Journal of Pharmacology and Experimental Therapeutics, 327(3), 746-759. Scopus107 Europe PMC95 |
| 2008 | Seaton, A., Scullin, P., Maxwell, P. J., Wilson, C., Pettigrew, J., Gallagher, R., . . . Waugh, D. J. J. (2008). Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation. Carcinogenesis, 29(6), 1148-1156. Scopus134 Europe PMC102 |
| 2008 | Waugh, D. J. J., & Wilson, C. (2008). The interleukin-8 pathway in cancer. Clinical Cancer Research, 14(21), 6735-6741. Scopus1853 Europe PMC1597 |
| 2008 | Wilson, C., Scullin, P., Worthington, J., Seaton, A., Maxwell, P., O'Rourke, D., . . . Waugh, D. J. J. (2008). Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer. British Journal of Cancer, 99(12), 2054-2064. Scopus31 Europe PMC23 |
| 2007 | MacManus, C. F., Pettigrew, J., Seaton, A., Wilson, C., Maxwell, P. J., Berlingeri, S., . . . Waugh, D. J. J. (2007). Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells. Molecular Cancer Research, 5(7), 737-748. Scopus99 Europe PMC89 |
| 2007 | Maxwell, P. J., Gallagher, R., Seaton, A., Wilson, C., Scullin, P., Pettigrew, J., . . . Waugh, D. J. J. (2007). HIF-1 and NF-κB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene, 26(52), 7333-7345. Scopus194 Europe PMC165 |
| 2006 | Hill, A., McFarlane, S., Mulligan, K., Gillespie, H., Draffin, J. E., Trimble, A., . . . Waugh, D. J. J. (2006). Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells. Oncogene, 25(45), 6079-6091. Scopus108 Europe PMC104 |
| 2006 | Hill, A., McFarlane, S., Johnston, P. G., & Waugh, D. J. J. (2006). The emerging role of CD44 in regulating skeletal micrometastasis. Cancer Letters, 237(1), 1-9. Scopus68 Europe PMC52 |
| 2005 | Murphy, C., McGurk, M., Pettigrew, J., Santinelli, A., Mazzucchelli, R., Johnston, P. G., . . . Waugh, D. J. J. (2005). Nonapical and cytoplasmic expression of interleukin-8, CXCR1, and CXCR2 correlates with cell proliferation and microvessel density in prostate cancer. Clinical Cancer Research, 11(11), 4117-4127. Scopus185 Europe PMC159 |
| 2004 | Draffin, J. E., McFarlane, S., Hill, A., Johnston, P. G., & Waugh, D. J. J. (2004). CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells. Cancer Research, 64(16), 5702-5711. Scopus239 Europe PMC182 |
| 2003 | Smith, D. D., Saha, S., Fang, G., Schaffert, C., Waugh, D. J. J., Zeng, W., . . . Abel, P. W. (2003). Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity. Journal of Medicinal Chemistry, 46(12), 2427-2435. Scopus24 Europe PMC16 |
| 2001 | Zuscik, M. J., Chalothorn, D., Hellard, D., Deighan, C., McGee, A., Daly, C. J., . . . Perez, D. M. (2001). Hypotension, Autonomic Failure, and Cardiac Hypertrophy in Transgenic Mice Overexpressing the α1B-Adrenergic Receptor. Journal of Biological Chemistry, 276(17), 13738-13743. Scopus94 Europe PMC62 |
| 2001 | Waugh, D. J. J., Gaivin, R. J., Zuscik, M. J., Gonzalez-Cabrera, P., Ross, S. A., Yun, J., & Perez, D. M. (2001). Phe-308 and Phe-312 in transmembrane domain 7 are major sites of α1-adrenergic receptor antagonist binding: Imidazoline agonists bind like antagonists. Journal of Biological Chemistry, 276(27), 25366-25371. Scopus62 Europe PMC45 |
| 2000 | Zuscik, M. J., Sands, S., Ross, S. A., Waugh, D. J. J., Gaivin, R. J., Morilak, D., & Perez, D. M. (2000). Overexpression of the α(1B)-adrenergic receptor causes apoptotic neurodegeneration: Multiple system atrophy. Nature Medicine, 6(12), 1388-1394. Scopus128 Europe PMC88 |
| 2000 | McCune, D. F., Edelmann, S. E., Olges, J. R., Post, G. R., Waldrop, B. A., Waugh, D. J. J., . . . Piascik, M. T. (2000). Regulation of the cellular localization and signaling properties of the α(1B)- and α(1D)-adrenoceptors by agonists and inverse agonists. Molecular Pharmacology, 57(4), 659-666. Scopus94 Europe PMC63 |
| 2000 | Waugh, D. J. J., Zhao, M. M., Zuscik, M. J., & Perez, D. M. (2000). Novel aromatic residues in transmembrane domains IV and V involved in agonist binding at α(1a)-adrenergic receptors. Journal of Biological Chemistry, 275(16), 11698-11705. Scopus21 Europe PMC16 |
| 1999 | Waugh, D. J. J., Bookman, C. S., Smith, D. D., & Abel, P. W. (1999). Limitations in using peptide drugs to characterize calcitonin gene- related peptide receptors. Journal of Pharmacology and Experimental Therapeutics, 289(3), 1419-1426. Scopus32 Europe PMC19 |
| 1999 | Waugh, D. J. J., Gaivin, R. J., Damron, D. S., Murray, P. A., & Perez, D. M. (1999). Binding, partial agonism, and potentiation of α1-adrenergic receptor function by benzodiazepines: A potential site of allosteric modulation. Journal of Pharmacology and Experimental Therapeutics, 291(3), 1164-1171. Scopus30 Europe PMC18 |
| 1998 | Saha, S., Waugh, D. J. J., Zhao, P., Abel, P. W., & Smith, D. D. (1998). Role of conformational constraints of position 7 of the disulphide bridge of h-α-CGRP derivatives in their agonist versus antagonist properties. Journal of Peptide Research, 52(2), 112-120. Scopus14 Europe PMC10 |
| 1998 | Porter, J. E., Edelmann, S. E., Waugh, D. J., Piascik, M. T., & Perez, D. M. (1998). The agonism and synergistic potentiation of weak partial agonists by triethylamine in α1-adrenergic receptor activation: Evidence for a salt bridge as the initiating process. Molecular Pharmacology, 53(4), 766-771. Scopus6 Europe PMC3 |
| 1998 | Chartrel, N., Conlon, J. M., Collin, F., Braun, B., Waugh, D., Vallarino, M., & Vaudry, H. (1998). Urotensin II in the central nervous system of the frog Rana ridibunda - Biochemical characterization and immunohistochemical localization. Annals of the New York Academy of Sciences, 839(1), 506-507. Scopus9 Europe PMC8 |
| 1997 | Li, J., Matsuura, J. E., Waugh, D. J. J., Adrian, T. E., Abel, P. W., Manning, M. C., & Smith, D. D. (1997). Structure-Activity studies on position 14 of human α-calcitonin gene- related peptide. Journal of Medicinal Chemistry, 40(19), 3071-3076. Scopus10 Europe PMC3 |
| 1997 | Abel, P. W., Waugh, D., & Jeffries, W. B. (1997). Radioligand binding using 125I-labeled peptides.. Methods in Molecular Biology Clifton N J, 73, 323-329. Scopus9 Europe PMC1 |
| 1997 | Jeffries, W. B., Waugh, D., & Abel, P. W. (1997). Analysis of data from "cold saturation" radioligand binding experiments.. Methods in Molecular Biology Clifton N J, 73, 331-342. Scopus8 Europe PMC8 |
| 1996 | Conlon, J. M., Yano, K., Waugh, D., & Hazon, N. (1996). Distribution and molecular forms of urotensin II and its role in cardiovascular regulation in vertebrates. Journal of Experimental Zoology, 275(2-3), 226-238. Scopus113 Europe PMC83 |
| 1996 | Le Mevel, J. C., Olson, K. R., Conklin, D., Waugh, D., Smith, D. D., Vaudry, H., & Conlon, J. M. (1996). Cardiovascular actions of trout urotensin II in the conscious trout, Oncorhynchus mykiss. American Journal of Physiology Regulatory Integrative and Comparative Physiology, 271(5 40-5), R1335-R1343. Scopus55 Europe PMC40 |
| 1996 | Waugh, D., Charles, S., Bockman, D., Smith, D., & Abel, P. W. (1996). Cgrp receptors on porcine arteries. FASEB Journal, 10(3), A697. |
| 1996 | Chartrel, N., Conlon, J. M., Collin, F., Braun, B., Waugh, D., Vallarino, M., . . . Vaudry, H. (1996). Urotensin II in the central nervous system of the frog Rana ridibunda: Immunohistochemical localization and biochemical characterization. Journal of Comparative Neurology, 364(2), 324-339. Scopus52 Europe PMC45 |
| 1995 | Waugh, D., Youson, J., Mims, S. D., Sower, S., & Conlon, J. M. (1995). Urotensin II from the River Lamprey (Lampetra fluviatilis), the Sea Lamprey (Petromyzon marinus), and the Paddlefish (Polyodon spathula). General and Comparative Endocrinology, 99(3), 323-332. Scopus34 Europe PMC25 |
| 1995 | Waugh, D., Anderson, G., Armour, K. J., Balment, R. J., Hanzon, N., & Conlon, J. M. (1995). A Peptide from the Caudal Neurosecretory System of the Dogfish Scyliorhinus canicula That Is Structurally Related to Urotensin I. General and Comparative Endocrinology, 99(3), 333-339. Scopus25 Europe PMC18 |
| 1995 | Waugh, D., Groff, K. E., Platzack, B., Youson, J. H., Olson, K. R., & Conlon, J. M. (1995). Isolation, localization, and cardiovascular activity of tachykinins from the stomach of the bowfin Amia calva. American Journal of Physiology Regulatory Integrative and Comparative Physiology, 269(3 38-3), R565-R571. Scopus16 Europe PMC9 |
| 1995 | Waugh, D., Bondareva, V., Rusakov, Y., Bjenning, C., Nielsen, P. F., & Conlon, J. M. (1995). Tachykinins with unusual structural features from a urodele, the amphiuma, an elasmobranch, the hammerhead shark, and an agnathan, the river lamprey. Peptides, 16(4), 615-621. Scopus33 Europe PMC28 |
| 1994 | Waugh, D., Sower, S., Bjenning, C., & Conlon, J. M. (1994). Novel tachykinins from the brain of the sea lamprey, Petromyzon marinus, and the skate, Raja rhina. Peptides, 15(1), 155-161. Scopus25 Europe PMC19 |
| 1993 | WAUGH, D., WANG, Y., HAZON, N., BALMENT, R. J., & CONLON, J. M. (1993). Primary structures and biological activities of substance‐P‐related peptides from the brain of the dogfish, Scyliorhinus canicula. European Journal of Biochemistry, 214(2), 469-474. Scopus29 Europe PMC19 |
| 1993 | Waugh, D., & Conlon, J. M. (1993). Purification and Characterization of Urotensin II from the Brain of a Teleost (Trout, Oncorhynchus mykiss) and an Elasmobranch (Skate, Raja rhina). General and Comparative Endocrinology, 92(3), 419-427. Scopus44 Europe PMC31 |
| Year | Citation |
|---|---|
| 2018 | Armstrong, C. W. D., Lyubomska, O., LaBonte, M. J., & Waugh, D. J. J. (2018). Protocols for studies on genetically engineered mouse models in prostate cancer. In Z. Lulig (Ed.), Source details - Title: Prostate Cancer (Vol. 1786, pp. 195-206). US: Springer. DOI |
| 2009 | Waugh, D. J. J., McClatchey, A., Montgomery, N., & McFarlane, S. (2009). Adhesion and Penetration: Two Sides of CD44 Signal Transduction Cascades in the Context of Cancer Cell Metastasis. In Hyaluronan in Cancer Biology (pp. 109-125). Elsevier. DOI Scopus5 |
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Targeting Inhibitory kappa B kinase α (IKKα): a new treatment paradigm for inflammatory-driven cancers, Medical Research Council - Developmental Pathway Funding Scheme, 28/08/2024 - 27/08/2027
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