David Torpy
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Torpy is Senior Endocrinologist and Deputy Director, Endocrine and Metabolic Unit, Royal Adelaide Hospital. He is also Professor of Medicine at the University of Adelaide School of Medicine. His research interests predominantly involve studies of the hypothalamic-pituitary-adrenal axis and stress. Recent specific areas have included corticosteroid-binding globulin (CBG) genetic variants and their effect on the stress response, immune-HPA interactions involving CBG in inflammatory states, adrenal function in septic shock, maternal cortisolaemia in complicated pregnancies, inherited forms of adrenal dysfunction causing Cushing’s, adrenocortical carcinoma, opioids and adrenal function, the stress axis in hypoglycaemia unawareness, and cortisone dosing and well-being in Addison’s disease.
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Appointments
Date Position Institution name 2012 - ongoing Professor, Discipline of Medicine University of Adelaide 2011 - ongoing Deputy Director, Endocrine & Metabolic Unit Royal Adelaide Hospital, Adelaide 2002 - ongoing Senior Consultant Endocrinologist Royal Adelaide Hospital 2002 - 2012 Associate Professor, Discipline of Medicine University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2012 Award Prof Derek Frewin AO Citation for Clinical Teaching – Recognised by MBBS students, School of Medicine University of Adelaide Australia - -
Education
Date Institution name Country Title 1996 University of Queensland Australia PhD 1991 Royal Australasian College of Physicians Australia Fellowship of the Royal Australasian College of Physicians 1984 University of Adelaide Australia MBBS -
Postgraduate Training
Date Title Institution Country 1995 - 1998 PhD University of Queensland Australia -
Certifications
Date Title Institution name Country 1993 ECFMG Certification Educational Commission for Foreign Medical Graduates United States -
Research Interests
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Journals
Year Citation 2025 Rushworth, R. L., Falhammar, H., & Torpy, D. J. (2025). Adrenal Crisis and Adrenal Insufficiency Admissions in Patients 30–59 Years: Contribution of Psychosocial Factors. Clinical Endocrinology, 102(3), 245-254.
2025 Willemsen, A. L., Torpy, D. J., De Sousa, S. M. C., Falhammar, H., & Rushworth, R. L. (2025). 17α-Hydroxylase/17,20-lyase Deficiency (17-OHD): A Meta-analysis of Reported Cases. Journal of Clinical Endocrinology and Metabolism, 110(4), e1261-e1271.
2025 Lee, J. H., Sumer-Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567, 8 pages.
Scopus1 WoS1 Europe PMC12025 Torpy, H., Chau, T. H., Chatterjee, S., Chernykh, A., Torpy, D. J., Meyer, E. J., & Thaysen-Andersen, M. (2025). Impact of different pathogen classes on the serum N-glycome in septic shock. BBA Advances, 7, 100138-1-100138-9.
Scopus12025 Candy, N. G., Mignone, E., Quick, E., Koszyca, B., Brown, A., Chapman, I. M., . . . De Sousa, S. M. C. (2025). The role of BRAF testing of Rathke's cleft cysts to identify missed papillary craniopharyngioma.. Pituitary, 28(1), 30.
Scopus2 WoS22025 Ramsay, S. D., Nenke, M. A., Meyer, E. J., Torpy, D. J., & Young, R. L. (2025). Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy. Frontiers in Endocrinology, 16, 1508848-1-1508848-16.
Scopus1 WoS1 Europe PMC12025 Chernykh, A., Sumer-Bayraktar, Z., Lee, J. H., Meyer, E. J., Torpy, D. J., & Thaysen-Andersen, M. (2025). RCL glycosylation of serum corticosteroid-binding globulin: implications in cortisol delivery and septic shock. Glycobiology, 35(4), cwaf013-1-cwaf013-10.
2025 Lin, R., Hii, M., Lim, W., Huynh, L., Marathe, J., Steele, P., . . . Ong, G. (2025). Diagnosis and Management of Severe Left Main Disease With Concurrent Severe Thyrotoxicosis: A Case Report. Heart, Lung and Circulation, 34, S240.
2024 Peel, A., Rushworth, R. L., & Torpy, D. J. (2024). Novel agents to treat adrenal insufficiency: findings of preclinical and early clinical trials. Expert Opinion on Investigational Drugs, 33(2), 115-126.
Scopus5 WoS7 Europe PMC42024 Nowell, A., Torres, S. J., Hall, S. J., Keske, M. A., Torpy, D. J., Parker, L., . . . Turner, A. I. (2024). Is high salt intake inducing obesity via production of cortisol? A novel working hypothesis and pilot study. European Journal of Nutrition, 63(4), 1315-1327.
WoS1 Europe PMC12024 De Sousa, S. M. C., Jukes, A. K., Candy, N. G., Chapman, I. M., Torpy, D. J., Shivalingam, B., . . . Santoreneos, S. (2024). Tumour fibrosis in dopamine agonist-exposed prolactinomas is a diminishing concern.. Nat Rev Endocrinol, 20(5), 314.
Scopus6 WoS6 Europe PMC32024 De Sousa, S. M. C., Mccormack, A., Orsmond, A., Shen, A., Yates, C. J., Clifton-Bligh, R., . . . Scott, H. S. (2024). Increased Prevalence of Germline Pathogenic CHEK2 Variants in Individuals With Pituitary Adenomas. Journal of Clinical Endocrinology and Metabolism, 109(11), 2720-2728.
Scopus5 WoS5 Europe PMC72024 Torpy, D. J., & Lim, W. T. (2024). Glucocorticoid-induced adrenal suppression: physiological basis and strategies for glucocorticoid weaning. Medical Journal of Australia, 220(10), 1 page.
Scopus12024 Ragnarsson, O., Juhlin, C. C., Torpy, D. J., & Falhammar, H. (2024). A clinical perspective on ectopic Cushing's syndrome. Trends in Endocrinology and Metabolism, 35(4), 347-360.
Scopus25 WoS23 Europe PMC222024 Maiden, M. J., Torpy, D. J., Ludbrook, G. L., Clarke, I. J., Chacko, B., Nash, C. H., . . . Kuchel, T. R. (2024). Triiodothyronine supplementation in a sheep model of intensive care. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 28(2), 7 pages.
2024 Lee, J. H., Meyer, E. J., Nenke, M. A., Lightman, S. L., & Torpy, D. J. (2024). Cortisol, Stress, and Disease-Bidirectional Associations; Role for Corticosteroid-Binding Globulin?. Journal of Clinical Endocrinology and Metabolism, 109(9), 2161-2172.
Scopus5 WoS4 Europe PMC22024 Clarke, B. M., Kireta, S., Johnston, J., Christou, C., Greenwood, J. E., Hurtado, P. R., . . . Torpy, D. J. (2024). In Vivo Formation of Adrenal Organoids in a Novel Porcine Model of Adrenocortical Cell Transplantation.. Endocrinology, 165(8), 19 pages.
Scopus1 WoS1 Europe PMC32024 Hayes, A. G., Stowasser, M., Umapathysivam, M. M., Falhammar, H., & Torpy, D. J. (2024). Approach to the Patient: Reninoma. Journal of Clinical Endocrinology and Metabolism, 109(2), e809-e816.
Scopus6 WoS8 Europe PMC72023 De Sousa, S. M. C., Wu, K. H. C., Colclough, K., Rawlings, L., Dubowsky, A., Monnik, M., . . . Torpy, D. J. (2023). Identification of monogenic diabetes in an Australian cohort using the Exeter maturity-onset diabetes of the young (MODY) probability calculator and next-generation sequencing gene panel testing. Acta Diabetologica: an international journal devoted to the study of clinical and experimental diabetes and metabolism, 61(2), 181-188.
Scopus3 WoS4 Europe PMC42023 Torpy, D. J., & Lim, W. T. (2023). Glucocorticoid-induced adrenal suppression: physiological basis and strategies for glucocorticoid weaning. Medical Journal of Australia, 219(10), 444-447.
Scopus4 WoS4 Europe PMC22023 Ganni, R., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2023). Response to Letter to the Editor From Yu: “Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis”. Journal of Clinical Endocrinology and Metabolism, 108(10), e1162.
Scopus12023 Rushworth, R. L., Falhammar, H., & Torpy, D. J. (2023). Factors underlying a disproportionate increase in hospital admissions for adrenal insufficiency in women aged 20-29 years. Frontiers in Endocrinology, 14, 8 pages.
Scopus2 WoS2 Europe PMC12023 De Sousa, S. M. C., Shen, A., Yates, C. J., Clifton-Bligh, R., Santoreneos, S., King, J., . . . Scott, H. S. (2023). <i>PAM</i> variants in patients with thyrotrophinomas, cyclical Cushing's disease and prolactinomas. FRONTIERS IN ENDOCRINOLOGY, 14, 10 pages.
WoS6 Europe PMC52023 Lee, J. H., & Torpy, D. J. (2023). Adrenal insufficiency in pregnancy: Physiology, diagnosis, management and areas for future research. Reviews in Endocrine and Metabolic Disorders, 24(1), 57-69.
Scopus10 WoS9 Europe PMC92023 Umapathysivam, M. M., Morgan, B., Bischoff, C., Hayes, A., Wilks, M., Stowasser, M., & Torpy, D. J. (2023). Intraprocedural cortisol testing improves adrenal vein cannulation success and diagnostic accuracy in assessment of primary aldosteronism, in a medium throughput centre. Journal of Human Hypertension, 37(9), 783-787.
Scopus8 WoS7 Europe PMC52023 Candy, N. G., Jukes, A. K., Van Der Veken, J., Torpy, D. J., Vrodos, N., Santoreneos, S., . . . Psaltis, A. J. (2023). The Learning Curve for Endoscopic Endonasal Transsphenoidal Pituitary Surgery: Evaluating Endocrine Outcomes.. J Clin Neurosci, 120, 14-22.
Scopus2 WoS2 Europe PMC12023 Heath, M., Torpy, D. J., & Rushworth, R. L. (2023). An analysis of the utilisation of medical identification jewellery among children and young adults with type 1 diabetes mellitus in Australia. Endocrine, 79(1), 72-79.
Scopus2 WoS2 Europe PMC12023 Graves, L. E., Torpy, D. J., Coates, P. T., Alexander, I. E., Bornstein, S. R., & Clarke, B. (2023). Future Directions for Adrenal Insufficiency: Cellular Transplantation and Genetic Therapies. Journal of Clinical Endocrinology and Metabolism, 108(6), 1273-1289.
Scopus9 WoS8 Europe PMC82023 Hayes, A. G., Shirazi, M. G., Thiyagarajah, A., Torpy, D. J., & De Sousa, S. M. C. (2023). Cabergoline-associated valvulopathy of the tricuspid valve in the treatment of prolactinoma. Endocrine Oncology, 3(1), e220086.
2023 Lee, J. H., Meyer, E. J., Nenke, M. A., Falhammar, H., & Torpy, D. J. (2023). Corticosteroid-binding globulin (CBG): spatiotemporal distribution of cortisol in sepsis. Trends in Endocrinology and Metabolism, 34(3), 181-190.
Scopus17 WoS14 Europe PMC162023 Lee, J. H., Nenke, M. A., Flabouris, K., Torpy, D. J., & Meyer, E. J. (2023). Plasma corticosteroid-binding globulin concentrations are preserved in mild cirrhosis. Liver International, 43(3), 740-741.
Scopus12023 Rushworth, R. L., & Torpy, D. J. (2023). The Changing Epidemiology of Adrenal Insufficiency: Iatrogenic Factors Predominate. Journal of the Endocrine Society, 7(3), 13 pages.
Scopus14 WoS15 Europe PMC112023 Ganni, R., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2023). Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis. Journal of Clinical Endocrinology and Metabolism, 108(9), E885-E892.
Scopus6 WoS6 Europe PMC22022 Raftopulos, N. L., Torpy, D. J., & Louise Rushworth, R. (2022). Epidemiology of acute pancreatitis in Australia from 2007–2019. ANZ Journal of Surgery, 92(1-2), 92-98.
Scopus5 WoS6 Europe PMC62022 Hayes, A. G., Rushworth, R. L., & Torpy, D. J. (2022). Risk assessment, diagnosis, and treatment of cancer treatment-related adrenal insufficiency. Expert Review of Endocrinology and Metabolism, 17(1), 21-33.
Scopus5 WoS5 Europe PMC42022 Saranapala, D. M. M. K., Baranoff, J., Rushworth, R. L., Westley, I., Collins, K., Burke, A. L. J., . . . Torpy, D. J. (2022). The effect of cognitive behavioral stress management on perceived stress, biological stress markers and weight loss/regain, from a diet-induced weight loss program: A randomized controlled trial. Comprehensive Psychoneuroendocrinology, 10, 1-9.
Scopus5 WoS2 Europe PMC12022 Meyer, E. J., Nenke, M. A., Davies, M. L., Chapman, M., Rankin, W., Rushworth, R. L., & Torpy, D. J. (2022). Corticosteroid-Binding Globulin Deficiency Independently Predicts Mortality in Septic Shock. Journal of Clinical Endocrinology and Metabolism, 107(6), 1636-1646.
Scopus17 WoS16 Europe PMC122022 Wu, D., Bampton, T. J., Scott, H. S., Brown, A., Kassahn, K., Drogemuller, C., . . . Coates, P. T. (2022). The clinical and genetic features of hereditary pancreatitis in South Australia.. Medical Journal of Australia, 216(11), 578-582.
Scopus6 WoS4 Europe PMC42022 Rushworth, R. L., Chrisp, G. L., Bownes, S., Torpy, D. J., & Falhammar, H. (2022). Adrenal crises in adolescents and young adults. Endocrine, 77(1), 1-10.
Scopus15 WoS14 Europe PMC112022 Hayes, A. G., Umapathysivam, M. M., & Torpy, D. J. (2022). Accidental exposure to glimepiride from adulterated medication resulting in severe hypoglycaemia. Endocrinology Diabetes and Metabolism Case Reports, 2022(1), 4 pages.
Scopus1 WoS12022 Lao, L., Bourdeau, I., Gagliardi, L., He, X., Shi, W., Hao, B., . . . Wu, J. (2022). ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia. Nucleic Acids Research, 50(11), 6343-6367.
Scopus23 WoS23 Europe PMC232022 Chrisp, G. L., Quartararo, M., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2022). Trends in hospital admissions for adrenal insufficiency in adolescents and young adults in the 21st century. Frontiers in Endocrinology, 13, 11 pages.
Scopus11 WoS7 Europe PMC62022 Meyer, E. J., Nenke, M. A., Davies, M. L., Chapman, M., Rankin, W., Rushworth, R. L., & Torpy, D. J. (2022). Erratum to: "Corticosteroid-Binding Globulin Deficiency Independently Predicts Mortality in Septic Shock" (The Journal of Clinical Endocrinology and Metabolism (2022) DOI: 10.1210/clinem/dgac035). Journal of Clinical Endocrinology and Metabolism, 107(8), E3547.
2022 Hensman, C. J., Gooley, J. L., Januszewski, A. S., Lee, M. H., MacIsaac, R. J., Boston, R. C., . . . Jenkins, A. J. (2022). Insulin antibodies are prevalent in adults with type 1 diabetes referred for islet cell transplantation and are modified by islet transplantation and immunosuppression: an Australian experience. Internal Medicine Journal, 52(8), 1434-1436.
2021 Jalleh, R., & Torpy, D. J. (2021). The Emerging Role of Copeptin.. The Clinical biochemist. Reviews, 42(1), 17-25.
Europe PMC192021 Bampton, T. J., Holmes-Walker, D. J., Drogemuller, C. J., Radford, T., Anderson, P., Etherton, C., . . . Australian Islet Consortium. (2021). Australian experience with total pancreatectomy with islet autotransplantation to treat chronic pancreatitis. ANZ Journal of Surgery, 91(12), 2663-2668.
Scopus5 WoS4 Europe PMC52021 Bichard, L. K., Rushworth, R. L., & Torpy, D. J. (2021). Flash Glucose Monitoring Compared to Capillary Glucose Levels in Patients With Diabetic Ketoacidosis: Potential Clinical Applications. Endocrine Practice, 27(8), 813-818.
Scopus8 WoS7 Europe PMC72021 Lubomski, A., Falhammar, H., Torpy, D. J., & Rushworth, R. L. (2021). The epidemiology of primary and secondary adrenal malignancies and associated adrenal insufficiency in hospitalised patients: an analysis of hospital admission data, NSW, Australia. BMC Endocrine Disorders, 21(1), 10 pages.
Scopus6 WoS6 Europe PMC42021 Meyer, E. J., Spangenberg, L., Ramírez, M. J., De Sousa, S. M. C., Raggio, V., & Torpy, D. J. (2021). CBG Montevideo: A Clinically Novel SERPINA6 Mutation Leading to Haploinsufficiency of Corticosteroid-binding Globulin. Journal of the Endocrine Society, 5(9), 8 pages.
Scopus8 WoS7 Europe PMC52021 Rushworth, R. L., Goubar, T., Ostman, C., McGrath, S., & Torpy, D. J. (2021). Interaction between hypotension and age on adrenal crisis diagnosis. Endocrinology Diabetes and Metabolism, 4(2), 5 pages.
Scopus4 WoS4 Europe PMC52021 Chatterjee, S., Kawahara, R., Tjondro, H. C., Shaw, D. R., Nenke, M. A., Torpy, D. J., & Thaysen-Andersen, M. (2021). Serum N-glycomics stratifies bacteremic patients infected with different pathogens. Journal of Clinical Medicine, 10(3), 1-18.
Scopus18 WoS14 Europe PMC132021 Rushworth, R. L., Gouvoussis, N., Goubar, T., Maguire, A., Munns, C. F., Neville, K. A., & Torpy, D. J. (2021). Acute illness in children with secondary adrenal insufficiency. Clinical Endocrinology, 94(6), 913-919.
Scopus6 WoS6 Europe PMC72021 Chrisp, G. L., Quartararo, M., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2021). Use of medical identification jewellery in children and young adults with adrenal insufficiency in Australia. Endocrine, 72(2), 539-545.
Scopus8 WoS8 Europe PMC92021 Hamblin, P. S., Yeap, B. B., & Torpy, D. J. (2021). Sepsis and adrenal insufficiency: a potentially lethal combination. Medical Journal of Australia, 214(7), 334-334.e1.
2021 Hahner, S., Ross, R. J., Arlt, W., Bancos, I., Burger-Stritt, S., Torpy, D. J., . . . Quinkler, M. (2021). Adrenal insufficiency. Nature Reviews Disease Primers, 7(1), 19.
Scopus119 WoS106 Europe PMC892020 De Sousa, S. M. C., Baranoff, J., Rushworth, R. L., Butler, J., Sorbello, J., Vorster, J., . . . Torpy, D. J. (2020). Impulse control disorders in dopamine agonist-treated hyperprolactinemia: prevalence and risk factors.. The Journal of clinical endocrinology and metabolism, 105(3), 108-118.
Scopus59 WoS47 Europe PMC382020 Dean, B., Chrisp, G. L., Quartararo, M., Maguire, A. M., Hameed, S., King, B. R., . . . Rushworth, R. L. (2020). P450 oxidoreductase deficiency: A systematic review and meta-analysis of genotypes, phenotypes and their relationships.. The Journal of clinical endocrinology and metabolism, 105(3), e43-E54.
Scopus20 WoS11 Europe PMC132020 De Sousa, S. M. C., Manavis, J., Feng, J., Wang, P., Schreiber, A. W., Scott, H. S., & Torpy, D. J. (2020). A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease. BMC Endocrine Disorders, 20(1), 6 pages.
Scopus6 WoS6 Europe PMC52020 Chrisp, G. L., Torpy, D. J., Maguire, A. M., Quartararo, M., Falhammar, H., King, B. R., . . . Rushworth, R. L. (2020). The effect of patient-managed stress dosing on electrolytes and blood pressure in acute illness in children with adrenal insufficiency. Clinical Endocrinology, 93(2), 97-103.
Scopus7 WoS6 Europe PMC52020 Mortimer, B., Naganur, V. D., Satouris, P., Greenfield, J. R., Torpy, D. J., & Rushworth, R. L. (2020). Acute illness in patients with concomitant Addison's disease and type 1 diabetes mellitus: Increased incidence of hypoglycaemia and adrenal crises. Clinical Endocrinology, 93(2), 104-110.
Scopus9 WoS8 Europe PMC72020 Hodyl, N. A., Stark, M. J., Meyer, E. J., Lewis, J. G., Torpy, D. J., & Nenke, M. A. (2020). High binding site occupancy of corticosteroid-binding globulin by progesterone increases fetal free cortisol concentrations. European Journal of Obstetrics and Gynecology and Reproductive Biology, 251, 129-135.
Scopus7 WoS6 Europe PMC52020 Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2020). Adrenal crises in older patients. The Lancet Diabetes and Endocrinology, 8(7), 628-639.
Scopus35 WoS32 Europe PMC282020 Bichard, L. K., & Torpy, D. J. (2020). Diabetes insipidus complicating apoplexy during pregnancy: the potential use of copeptin. Internal Medicine Journal, 50(7), 877-879.
Scopus5 WoS2 Europe PMC12020 Clarke, B., Loudovaris, T., Radford, T., Drogemuller, C., Coates, P. T., & Torpy, D. (2020). Ambulatory intravenous insulin and islet cell transplantation to treat severe type III insulin hypersensitivity in a patient with type 1 diabetes mellitus. Clinical Case Reports, 8(12), 2758-2761.
Scopus1 WoS1 Europe PMC22020 Meyer, E. J., Torpy, D. J., Chernykh, A., Thaysen-Andersen, M., Nenke, M. A., Lewis, J., . . . Polyak, S. W. (2020). Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin. Protein Science, 29(12), 2495-2509.
Scopus10 WoS10 Europe PMC92020 De Sousa, S. M. C., Toubia, J., Hardy, T. S. E., Feng, J., Wang, P., Schreiber, A. W., . . . Torpy, D. J. (2020). Aberrant Splicing of SDHC in Families With Unexplained Succinate Dehydrogenase-Deficient Paragangliomas. Journal of the Endocrine Society, 4(12), 1-12.
Scopus12 WoS12 Europe PMC112019 Barthel, A., Benker, G., Berens, K., Diederich, S., Manfras, B., Gruber, M., . . . Bornstein, S. R. (2019). An Update on Addison's Disease. Experimental and Clinical Endocrinology and Diabetes, 127(2-3), 165-170.
Scopus74 WoS60 Europe PMC452019 Webster, A. C., Hedley, J. A., Anderson, P. F., Hawthorne, W. J., Radford, T., Drogemuller, C., . . . Olakkengil, S. (2019). Australia and New Zealand islet and pancreas transplant registry annual report 2018—islet donations, islet isolations, and islet transplants. Transplantation Direct, 5(2), 9 pages.
Scopus5 WoS3 Europe PMC32019 Rushworth, R. L., Chrisp, G. L., & Torpy, D. J. (2019). The use of medical identification jewellery in adults with adrenal insufficiency in Australia. Clinical Endocrinology, 91(1), 41-47.
Scopus8 WoS8 Europe PMC62019 Philpott, H., Dougherty, M., Torpy, D., & Dellon, E. (2019). Letter: reassuringly normal response to ACTH in children treated with swallowed topical corticosteroids for eosinophilic oesophagitis – authors’ reply. Alimentary Pharmacology and Therapeutics, 49(12), 1539.
2019 Tallis, P. H., Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2019). Adrenal insufficiency due to bilateral adrenal metastases – A systematic review and meta-analysis. Heliyon, 5(5), 8 pages.
Scopus33 WoS31 Europe PMC282019 De Sousa, S. M. C., Saleem, M., Rankin, W., & Torpy, D. J. (2019). Serum prolactin overestimation and risk of misdiagnosis. ENDOCRINOLOGY DIABETES & METABOLISM, 2(3), 4 pages.
WoS4 Europe PMC42019 Meyer, E. J., Nenke, M. A., Rankin, W., Lewis, J. G., Konings, E., Slager, M., . . . Torpy, D. J. (2019). Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality. Clinical Endocrinology, 90(1), 232-240.
Scopus14 WoS13 Europe PMC112019 Maiden, M. J., & Torpy, D. J. (2019). Thyroid Hormones in Critical Illness. Critical Care Clinics, 35(2), 375-388.
Scopus66 WoS54 Europe PMC452019 Goubar, T., Torpy, D. J., McGrath, S., & Rushworth, R. L. (2019). Prehospital Management of Acute Addison Disease: Audit of Patients Attending a Referral Hospital in a Regional Area.. Journal of the Endocrine Society, 3(12), 2194-2203.
Scopus12 WoS13 Europe PMC102019 Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2019). Adrenal Crisis. Reply. New England Journal of Medicine, 381(22), 2182-2183.
Scopus2 WoS22019 De Sousa, S. M. C., Wang, P. P. S., Santoreneos, S., Shen, A., Yates, C. J., Babic, M., . . . Scott, H. S. (2019). The Genomic Landscape of Sporadic Prolactinomas. Endocrine Pathology, 30(4), 318-328.
Scopus18 WoS18 Europe PMC182019 Louise Rushworth, R., Torpy, D. J., & Falhammar, H. (2019). Adrenal crisis. New England Journal of Medicine, 381(9), 852-861.
Scopus192 WoS165 Europe PMC1402019 Torpy, D. J. (2019). Commentary on article: Adrenal crisis in treated patients with Cushing’s syndrome. European Journal of Endocrinology, 181(4), C13-C15.
Scopus3 WoS5 Europe PMC22018 Chrisp, G. L., Maguire, A. M., Quartararo, M., Falhammar, H., King, B. R., Munns, C. F., . . . Rushworth, R. L. (2018). Variations in the management of acute illness in children with congenital adrenal hyperplasia: An audit of three paediatric hospitals. Clinical Endocrinology, 89(5), 577-585.
Scopus23 WoS23 Europe PMC192018 De Sousa, S. M. C., Hardy, T. S. E., Scott, H. S., & Torpy, D. J. (2018). Genetic testing in endocrinology. Clinical Biochemist Reviews, 39(1), 17-28.
Scopus16 Europe PMC92018 Kalra, S., Sahoo, A., Das, S., Kumar, K. V. S. H., Baliarsinha, A. K., Mohanty, B., . . . Acharya, K. (2018). The Bhubaneswar declaration on sports endocrinology, 2018. Indian Journal of Endocrinology and Metabolism, 22(7), S14-S16.
Scopus2 Europe PMC12018 Lamprecht, A., Sorbello, J., Jang, C., Torpy, D. J., & Inder, W. J. (2018). Secondary adrenal insufficiency and pituitary dysfunction in oral/transdermal opioid users with non-cancer pain. European Journal of Endocrinology, 179(6), 353-362.
Scopus40 WoS42 Europe PMC262018 Crowther, S., Rushworth, R., Rankin, W., Falhammar, H., Phillips, L., & Torpy, D. (2018). Trends in surgery, hospital admissions and imaging for pituitary adenomas in Australia. Endocrine, 59(2), 373-382.
Scopus13 WoS12 Europe PMC102018 Philpott, H., Dougherty, M. K., Reed, C. C., Caldwell, M., Kirk, D., Torpy, D. J., & Dellon, E. S. (2018). Systematic review: adrenal insufficiency secondary to swallowed topical corticosteroids in eosinophilic oesophagitis. Alimentary Pharmacology and Therapeutics, 47(8), 1071-1078.
Scopus60 WoS52 Europe PMC482018 Rushworth, R. L., Chrisp, G. L., & Torpy, D. J. (2018). Glucocorticoid-induced adrenal insufficiency: A study of the incidence in hospital patients and a review of peri-operative management. Endocrine Practice, 24(5), 437-445.
Scopus17 WoS16 Europe PMC122018 Trainer, P. J., Newell-Price, J. D. C., Ayuk, J., Aylwin, S. J. B., Rees, A., Drake, W., . . . Bidlingmaier, M. (2018). A randomised, open-label, parallel group phase 2 study of antisense oligonucleotide therapy in acromegaly. European Journal of Endocrinology, 179(2), 97-108.
Scopus34 WoS29 Europe PMC242018 Rushworth, R., Torpy, D., Stratakis, C., & Falhammar, H. (2018). Adrenal crises in children: perspectives and research directions. Hormone Research in Paediatrics, 89(5), 341-351.
Scopus45 WoS41 Europe PMC352017 De Sousa, S. M. C., McCormack, A. I., McGrath, S., & Torpy, D. J. (2017). Prolactin correction for adequacy of petrosal sinus cannulation may diminish diagnostic accuracy in Cushing's disease. Clinical Endocrinology, 87(5), 515-522.
Scopus24 WoS23 Europe PMC132017 Meyer, E. J., Nenke, M. A., Lewis, J. G., & Torpy, D. J. (2017). Corticosteroid-binding globulin: acute and chronic inflammation. Expert Review of Endocrinology and Metabolism, 12(4), 241-251.
Scopus18 WoS19 Europe PMC172017 De Sousa, S. M. C., Meyer, E. J., Rankin, W., Brautigan, P. J., Burt, M. G., & Torpy, D. J. (2017). Vasculogenic hyperprolactinemia: severe prolactin excess in association with internal carotid artery aneurysms. Pituitary, 20(6), 676-682.
Scopus5 WoS4 Europe PMC42017 Rushworth, R., Chrisp, G., Dean, B., Falhammar, H., & Torpy, D. (2017). Hospitalisation in Children with Adrenal Insufficiency and Hypopituitarism: Is There a Differential Burden between Boys and Girls and between Age Groups?. Hormone Research in Paediatrics, 88(5), 339-346.
Scopus17 WoS15 Europe PMC142017 De Sousa, S. M. C., Stowasser, M., Feng, J., Schreiber, A. W., Wang, P., Hahn, C. N., . . . Gagliardi, L. (2017). ARMC5 is not implicated in familial hyperaldosteronism type II (FH-II). Journal of Human Hypertension, 31(12), 857-859.
Scopus6 WoS3 Europe PMC52017 Rushworth, R., Torpy, D., & Falhammar, H. (2017). Adrenal crises: perspectives and research directions. Endocrine, 55(2), 336-345.
Scopus73 WoS59 Europe PMC522017 Nenke, M. A., Nielsen, S. T., Lehrskov, L. L., Lewis, J. G., Rankin, W., Møller, K., & Torpy, D. J. (2017). Pyrexia’s effect on the CBG-cortisol thermocouple, rather than CBG cleavage, elevates the acute free cortisol response to TNF-α in humans. Stress, 20(2), 183-188.
Scopus6 WoS6 Europe PMC52017 Rushworth, R. L., Bischoff, C., & Torpy, D. J. (2017). Preventing adrenal crises: home-administered subcutaneous hydrocortisone is an option. Internal Medicine Journal, 47(2), 231-232.
Scopus3 WoS2 Europe PMC32017 Du, Y. T., Roberts, A. P., & Torpy, D. J. (2017). Seizure induced by sudden cessation of pregabalin in a patient with chronic kidney disease. BMJ Case Reports, 2017, bcr-2016-219158.
Scopus5 Europe PMC22017 Nenke, M. A., Zeng, A., Meyer, E. J., Lewis, J. G., Rankin, W., Johnston, J., . . . Torpy, D. J. (2017). Differential Effects of Estrogen on Corticosteroid-Binding Globulin Forms Suggests Reduced Cleavage in Pregnancy. Journal of the Endocrine Society, 1(3), 202-210.
Scopus35 WoS30 Europe PMC212017 Torpy, D. J. (2017). GLUCOCORTICOID REPLACEMENT IN CHRONIC ADRENAL INSUFFICIENCY: EVALUATING THE EVIDENCE FOR OPTIMAL THERAPY.. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 23(1), 113-115.
Scopus2 WoS1 Europe PMC12017 De Sousa, S., Chapman, I., Falhammar, H., & Torpy, D. (2017). Dopa-testotoxicosis: disruptive hypersexuality in hypogonadal men with prolactinomas treated with dopamine agonists. Endocrine, 55(2), 618-624.
Scopus43 WoS36 Europe PMC302017 Nenke, M. A., Lewis, J. G., Rankin, W., Shaw, D., & Torpy, D. J. (2017). Corticosteroid-binding globulin cleavage may be pathogen-dependent in bloodstream infection. Clinica Chimica Acta, 464, 176-181.
Scopus7 WoS7 Europe PMC72017 Tirosh, A., Papadakis, G., Chittiboina, P., Lyssikatos, C., Belyavskaya, E., Keil, M., . . . Stratakis, C. (2017). 3D Volumetric Measurements of GH Secreting Adenomas Correlate with Baseline Pituitary Function, Initial Surgery Success Rate, and Disease Control. Hormone and Metabolic Research, 49(06), 440-445.
2016 Gerstein, H. C., Bosch, J., Dagenais, G. R., Díaz, R., Jung, H., Maggioni, A. P., . . . Bustos, B. (2016). Cardiovascular and other outcomes postintervention with insulin glargine and omega-3 fatty acids (ORIGINALE). Diabetes Care, 39(5), 709-716.
Scopus52 WoS50 Europe PMC412016 Falhammar, H., & Torpy, D. J. (2016). A 42-year-old man presented with adrenal incidentaloma due to non-classic congenital adrenal hyperplasia with a novel CYP21A2 mutation. Internal Medicine Journal, 46(9), 1115-1116.
Scopus4 WoS4 Europe PMC32016 Baumann, A., Conway, J., Rosenfeld, H., Le Cong, T., Torpy, D. J., & Rankin, W. (2016). Non-islet cell tumour-induced hypoglycaemia secondary to haemangiopericytoma: A case report.. Pathology, 48 Suppl 1, S89-S90.
2016 Nenke, M. A., Lewis, J. G., Rankin, W., & Torpy, D. J. (2016). Evidence of Reduced CBG Cleavage in Abdominal Obesity: A Potential Factor in Development of the Metabolic Syndrome.. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 48(9), 620.
Europe PMC52016 De Sousa, S. M. C., Kassahn, K. S., McIntyre, L. C., Chong, C. E., Scott, H. S., & Torpy, D. J. (2016). Case report of whole genome sequencing in the XY female: identification of a novel SRY mutation and revision of a misdiagnosis of androgen insensitivity syndrome. BMC Endocrine Disorders, 16(1), 58-1-58-7.
Scopus7 WoS4 Europe PMC42016 Henley, D., Brown, S., Pennell, C., Lye, S., & Torpy, D. (2016). Evidence for central hypercortisolism and elevated blood pressure in adolescent offspring of mothers with pre-eclampsia. Clinical Endocrinology, 85(4), 583-589.
Scopus24 WoS23 Europe PMC162016 Meyer, E., Nenke, M., Rankin, W., Lewis, J., & Torpy, D. (2016). Corticosteroid-binding globulin: a review of basic and clinical advances. Hormone and Metabolic Research, 48(6), 359-371.
Scopus107 WoS97 Europe PMC882016 Nenke, M., Lewis, J., Rankin, W., & Torpy, D. (2016). Evidence of Reduced CBG Cleavage in Abdominal Obesity: A Potential Factor in Development of the Metabolic Syndrome. Hormone and Metabolic Research, 48(8), 523-528.
Scopus8 WoS7 Europe PMC42016 Nenke, M., Lewis, J., Rankin, W., McWilliams, L., Metcalf, R., Proudman, S., & Torpy, D. (2016). Reduced corticosteroid-binding globulin cleavage in active rheumatoid arthritis. Clinical Endocrinology, 85(3), 369-377.
Scopus11 WoS8 Europe PMC82016 Nenke, M., Holmes, M., Rankin, W., Lewis, J., & Torpy, D. (2016). Corticosteroid-binding globulin cleavage is paradoxically reduced in alpha-1 antitrypsin deficiency: implications for cortisol homeostasis. Clinica Chimica Acta, 452, 27-31.
Scopus20 WoS19 Europe PMC182016 Falhammar, H., & Torpy, D. (2016). Congenital adrenal hyperplasia due to 21-hydroxylase deficiency presenting as adrenal incidentaloma: a systematic review and meta-analysis. Endocrine Practice, 22(6), 736-752.
Scopus56 WoS46 Europe PMC382016 Maiden, M., Chapman, M., Torpy, D., Kuchel, T., Clarke, I., Nash, C., . . . Ludbrook, G. (2016). Triiodothyronine administration in a model of septic shock: A randomized blinded placebo-controlled trial. Critical Care Medicine, 44(6), 1153-1160.
Scopus5 WoS7 Europe PMC62016 Bornstein, S., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G., . . . Torpy, D. (2016). Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism, 101(2), 364-389.
Scopus1323 WoS1130 Europe PMC9352016 Rushworth, R., Falhammar, H., Munns, C., Maguire, A., & Torpy, D. (2016). Hospital admission patterns in children with CAH: admission rates and adrenal crises decline with age. International Journal of Endocrinology, 2016, 5748264-1-5748264-7.
Scopus21 WoS23 Europe PMC192015 Rushworth, R., & Torpy, D. (2015). Adrenal insufficiency in Australia: Is it possible that the use of lower dose, short-acting glucocorticoids has increased the risk of adrenal crises?. Hormone and Metabolic Research, 47(6), 427-432.
Scopus33 WoS33 Europe PMC282015 Nenke, M., Haylock, C., Rankin, W., Inder, W., Gagliardi, L., Eldridge, C., . . . Torpy, D. (2015). Low-dose hydrocortisone replacement improves wellbeing and pain tolerance in chronic pain patients with opioid-induced hypocortisolemic responses. A pilot randomized, placebo-controlled trial. Psychoneuroendocrinology, 56, 157-167.
Scopus27 WoS27 Europe PMC202015 Rushworth, R., & Torpy, D. (2015). Modern hydrocortisone replacement regimens in adrenal insufficiency patients and the risk of adrenal crisis. Hormone and Metabolic Research, 47(9), 637-642.
Scopus26 WoS26 Europe PMC202015 Louise Rushworth, R., Slobodian, P., & Torpy, D. J. (2015). Interruptions to supply of high-dose hydrocortisone tablets and the incidence of adrenal crises. Clinical Endocrinology, 83(6), 999-1000.
Scopus7 WoS6 Europe PMC32015 Petersen, K. S., Rushworth, R. L., Clifton, P. M., & Torpy, D. J. (2015). Recurrent nocturnal hypoglycaemia as a cause of morning fatigue in treated Addison's disease - favourable response to dietary management: A case report. BMC Endocrine Disorders, 15(1), 5 pages.
Scopus13 WoS11 Europe PMC102015 Marathe, C., Drogemuller, C., Marathe, J., Loudavaris, T., Hawthorne, W., O'Connell, P., . . . Torpy, D. (2015). Islet cell transplantation in Australia: screening, remote transplantation, and incretin hormone secretion in insulin independent patients. Hormone and Metabolic Research, 47(1), 16-23.
Scopus8 WoS8 Europe PMC62015 Dorin, R., Qualls, C., Torpy, D., Schrader, R., & Urban, F. (2015). Reversible increase in maximal cortisol secretion rate in septic shock. Critical Care Medicine, 43(3), 549-556.
Scopus13 WoS12 Europe PMC92015 Nenke, M., Rankin, W., Chapman, M., Stevens, N., Diener, K., Hayball, J., . . . Torpy, D. (2015). Depletion of high affinity corticosteroid-binding globulin corresponds to illness severity in sepsis and septic shock; clinical implications. Clinical Endocrinology, 82(6), 801-807.
Scopus51 WoS46 Europe PMC352015 Torpy, D. J. (2015). Screening for ACTH-dependent hypercortisolism in patients with pituitary incidentaloma. European Journal of Endocrinology, 172(4), C1-C4.
Scopus3 WoS3 Europe PMC32014 Jung, C., Greco, S., Nguyen, H., Ho, J., Lewis, J., Torpy, D., & Inder, W. (2014). Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers. BMC Endocrine Disorders, 14(1), 10 pages.
Scopus96 WoS80 Europe PMC732014 Gagliardi, L., Schreiber, A., Hahn, C., Feng, J., Cranston, T., Boon, H., . . . Scott, H. (2014). ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism, 99(9), E1784-E1792.
Scopus106 WoS92 Europe PMC802014 Gagliardi, L., Nenke, M., Thynne, T., von der Borch, J., Rankin, W., Henley, D., . . . Torpy, D. (2014). Continuous subcutaneous hydrocortisone infusion therapy in Addison's disease: a randomized, placebo-controlled clinical trial. The Journal of Clinical Endocrinology & Metabolism, 99(11), 4149-4157.
Scopus69 WoS60 Europe PMC472014 Nguyen, P., Lewis, J., Sneyd, J., Lee, R., Torpy, D., & Shorten, P. (2014). Development of a formula for estimating plasma free cortisol concentration from a measured total cortisol concentration when elastase-cleaved and intact corticosteroid binding globulin coexist. Journal of Steroid Biochemistry and Molecular Biology, 141, 16-25.
Scopus24 WoS22 Europe PMC172014 Rushworth, R., & Torpy, D. (2014). A descriptive study of adrenal crises in adults with adrenal insufficiency: increased risk with age and in those with bacterial infections. BMC Endocrine Disorders, 14(1), 79-1-79-8.
Scopus53 WoS52 Europe PMC402014 Gagliardi, L., Scott, H., Feng, J., & Torpy, D. (2014). A case of Aromatase deficiency due to a novel CYP19A1 mutation. BMC Endocrine Disorders, 14(1), 1-7.
Scopus38 WoS35 Europe PMC202013 Clifton, V., Hodyl, N., Fogarty, P., Torpy, D., Roberts, R., Nettelbeck, T., . . . Hetzel, B. (2013). The impact of iodine supplementation and bread fortification on urinary iodine concentrations in a mildly iodine deficient population of pregnant women in South Australia. Nutrition Journal, 12(1), 1-5.
Scopus43 WoS34 Europe PMC222013 Lim, W., Torpy, D., & Jeffries, W. (2013). The medical management of Cushing's syndrome during pregnancy. European Journal of Obstetrics Gynecology and Reproductive Biology, 168(1), 1-6.
Scopus55 WoS44 Europe PMC302013 O'Connell, P., Holmes-Walker, D., Goodman, D., Hawthorne, W., Loudovaris, T., Gunton, J., . . . Kay, T. (2013). Multicenter Australian trial of islet transplantation: Improving accessibility and outcomes. American Journal of Transplantation, 2013(13), 1850-1858.
Scopus100 WoS87 Europe PMC712013 Petersen, K., Torpy, D., Chapman, I., Guha, S., Clifton, P., Turner, K., & Keogh, J. (2013). Food label education does not reduce sodium intake in people with type 2 diabetes mellitus. A randomised controlled trial. Appetite, 68(1), 147-151.
Scopus28 WoS28 Europe PMC232012 Torpy, D. (2012). Combination chemotherapy in advanced adrenocortical carcinoma. New England Journal of Medicine, 366(23), 2189-2197.
Scopus708 WoS630 Europe PMC5222012 Gagliardi, L., Ling, K., Kok, C., Carolan, J., Brautigan, P., Kenyon, R., . . . Scott, H. (2012). Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocrine-Related Cancer, 19(3), 19-23.
Scopus6 WoS6 Europe PMC52012 Marathe, C., & Torpy, D. (2012). A role for corticosteroid-binding globulin variants in stress-related disorders. Expert Review of Endocrinology & Metabolism, 7(3), 301-308.
Scopus2 WoS3 Europe PMC12012 Torpy, D., Lundgren, B., Ho, J., Lewis, J., Scott, H., & Mericq, V. (2012). CBG Santiago: a novel CBG mutation. Journal of Clinical Endocrinology and Metabolism, 97(1), E151-E155.
Scopus28 WoS23 Europe PMC192012 Bosch, J., Gerstein, H. C., Dagenais, G. R., Díaz, R., Dyal, L., Jung, H., . . . Caccavo, A. (2012). N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. New England Journal of Medicine, 367(4), 309-318.
Scopus815 WoS731 Europe PMC6212012 Gerstein, H. C., Bosch, J., Dagenais, G. R., Díaz, R., Jung, H., Maggioni, A. P., . . . Bustamante Labarta, M. (2012). Basal insulin and cardiovascular and other outcomes in dysglycemia. New England Journal of Medicine, 367(4), 319-328.
Scopus1470 WoS1288 Europe PMC10192012 Ting, R. -D., Keech, A. C., Drury, P. L., Donoghoe, M. W., Hedley, J., Jenkins, A. J., . . . Stanton, K. (2012). Benefits and Safety of Long-Term Fenofibrate Therapy in People With Type 2 Diabetes and Renal Impairment The FIELD Study. DIABETES CARE, 35(2), 218-225.
WoS100 Europe PMC812011 Cizza, G., Bernardi, L., Smirne, N., Maletta, R., Tomaino, C., Costanzo, A., . . . Bruni, A. (2011). Clinical manifestations of highly prevalent corticosteroid-binding globulin mutations in a village in Southern Italy. Journal of Clinical Endocrinology and Metabolism, 96(10), E1684-E1693.
Scopus28 WoS25 Europe PMC192011 Simon, S., Torpy, D., Brophy, B., Blumbergs, P., Selva-Nayagam, D., & Crompton, J. (2011). Neuro-ophthalmic manifestations and outcomes of pituitary apoplexy - a life and sight-threatening emergency. New Zealand Medical Journal, 124(1335), 52-59.
Scopus20 WoS10 Europe PMC32011 Jung, C., Ho, J., Torpy, D., Rogers, A., Doogue, M., Lewis, J., . . . Inder, W. (2011). A longitudinal study of plasma and urinary cortisol in pregnancy and postpartum. Journal of Clinical Endocrinology and Metabolism, 96(5), 1533-1540.
Scopus326 WoS300 Europe PMC2492010 Ho, J., Chapman, M., O'Connor, S., Lam, S., Edwards, J., Ludbrook, G., . . . Torpy, D. (2010). Characteristics of plasma NOx levels in severe sepsis: High interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels. Clinical Endocrinology, 73(3), 413-420.
Scopus14 WoS13 Europe PMC112010 Wong, K., Wong, V., Ho, J., Torpy, D., McLean, M., & Cheung, N. (2010). High cortisol levels in hyperglycaemic myocardial infarct patients signify stress hyperglycaemia and predict subsequent normalization of glucose tolerance. Clinical Endocrinology, 72(2), 189-195.
Scopus21 WoS20 Europe PMC172010 Gagliardi, L., Ho, J., & Torpy, D. (2010). Corticosteroid-binding globulin: The clinical significance of altered levels and heritable mutations. Molecular and Cellular Endocrinology, 316(1), 24-34.
Scopus70 WoS66 Europe PMC542010 Gagliardi, L., Chapman, I., O'Loughlin, P., & Torpy, D. (2010). Screening for subclinical Cushing's Syndrome in Type 2 Diabetes Mellitus: Low false-positive rates with nocturnal salivary cortisol. Hormone and Metabolic Research, 42(4), 280-284.
Scopus22 WoS20 Europe PMC162010 Gagliardi, L., & Torpy, D. (2010). Subclinical Cushing's syndrome in adrenal incidentaloma: a common problem or an artefact of current diagnostic testing?. Clinical Endocrinology, 72(2), 277-278.
Scopus7 WoS7 Europe PMC72009 Gagliardi, L., Hotu, C., Casey, G., Braund, W., Ling, K., Dodd, T., . . . Torpy, D. (2009). Familial vasopressin-sensitive ACTH-independent macronodular adrenal hyperplasia (VPs-AIMAH): clinical studies of three kindreads. Clinical Endocrinology, 70(6), 883-891.
Scopus43 WoS38 Europe PMC322009 Pfeffer, M. A., Burdmann, E. A., Chen, C. -Y., Cooper, M. E., de Zeeuw, D., Eckardt, K. -U., . . . Toto, R. (2009). A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease. NEW ENGLAND JOURNAL OF MEDICINE, 361(21), 2019-2032.
WoS1643 Europe PMC13622008 Gerstein, H. C., Yusuf, S., Riddle, M., Ryden, L., Bosch, J., Richardson, L., . . . Falu, R. (2008). Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention). American Heart Journal, 155(1), 26-26.e13.
Scopus153 WoS165 Europe PMC1372008 Dorin, R., Pai, H., Ho, J., Lewis, J., Torpy, D., Urban, F., & Qualls, C. (2008). Validation of a simple method of estimating plasma free cortisol: Role of cortisol binding to albumin. Clinical Biochemistry, 42(1-2), 64-71.
Scopus48 WoS46 Europe PMC342008 Cukier, K., Tewari, N., Kurth, F., Schmid, H., Lai, C., & Torpy, D. (2008). Significant response to pasireotide (SOM230) in the treatment of a patient with persistent, refractory Cushing's disease. Clinical Endocrinology, 71(2), 305-307.
Scopus16 WoS16 Europe PMC112007 Torpy, D., & Ho, J. (2007). Corticosteroid-binding globulin gene polymorphisms: clinical implications and links to idiopathic chronic fatigue disorders. Clinical Endocrinology, 67(2), 161-167.
Scopus35 WoS28 Europe PMC242007 Ho, J., Lewis, J., O'Loughlin, P., Bagley, C., Romero, R., Dekker, G., & Torpy, D. (2007). Reduced maternal corticosteroid-binding globulin and cortisol levels in pre-eclampsia and gamete recipient pregnancies. Clinical Endocrinology, 66(6), 869-877.
Scopus74 WoS68 Europe PMC452007 Torpy, D. (2007). Misleading information for consumers. Medical Journal of Australia, 186(9), 483-484.
Scopus12007 Ho, J. T., Keogh, J. B., Bornstein, S. R., Ehrhart-Bornstein, M., Lewis, J. G., Clifton, P. M., & Torpy, D. J. (2007). Moderate weight loss reduces renin and aldosterone but does not influence basal or stimulated pituitary-adrenal axis function. Hormone and Metabolic Research, 39(9), 694-699.
Scopus53 WoS52 Europe PMC412007 Ho, J., & Torpy, D. J. (2007). Evaluation of adrenocortical function in adults. Australian Prescriber, 30(6), 147-149.
2006 Venkatesh, B., Prins, J., Torpy, D., Chapman, M., Joyce, C., Cooper, D. J., . . . Higgins, A. (2006). Relative adrenal insufficiency in sepsis: match point or deuce?. Critical Care and Resuscitation Journal of the Australasian Academy of Critical Care Medicine, 8(4), 376-380.
Scopus5 Europe PMC32006 Ho, J., Al Musalhi, H., Chapman, M., Quach, T., Thomas, P., Bagley, C., . . . Torpy, D. (2006). Septic shock and sepsis: A comparison of total and free plasma cortisol levels. Journal of Clinical Endocrinology and Metabolism, 91(1), 105-114.
Scopus278 WoS239 Europe PMC1792005 Bachmann, A., Sedgley, T., Jackson, R., Gibson, J., Young, R., & Torpy, D. (2005). Glucocorticoid receptor polymorphisms and post-traumatic stress disorder. PsychoNeuroendocrinology, 30(3), 297-306.
Scopus124 WoS114 Europe PMC892005 Lewis, J., Bagley, C., Elder, P., Bachmann, A., & Torpy, D. (2005). Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulin. Clinica Chimica Acta, 359(1-2), 189-194.
Scopus180 WoS166 Europe PMC1382005 Keech, A. C., Scott, R., Best, J., Forder, P., Taskinen, M. R., Simes, R. J., . . . Morris, S. (2005). Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: Baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]. Cardiovascular Diabetology, 4(1), 9 pages.
Scopus84 WoS52 Europe PMC672005 Ilias, I., Torpy, D. J., Pacak, K., Mullen, N., Wesley, R. A., & Nieman, L. K. (2005). Cushing's syndrome due to ectopic corticotropin secretion: Twenty years' experience at the National Institutes of Health. Journal of Clinical Endocrinology and Metabolism, 90(8), 4955-4962.
Scopus560 WoS498 Europe PMC4142004 Mitchell, E., Torpy, D. J., & Bagley, C. J. (2004). Pregnancy-associated corticosteroid-binding globulin: High resolution separation of glycan isoforms. Hormone and Metabolic Research, 36(6), 357-359.
Scopus28 WoS24 Europe PMC192004 Barter, P., Best, J., Colman, P., d'Emden, M., Davis, T., Drury, P., . . . Alard, F. (2004). The need for a large-scale trial of fibrate therapy in diabetes: The rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481]. Cardiovascular Diabetology, 3(1), 11 pages.
Scopus96 WoS74 Europe PMC602004 Kleinig, T., & Torpy, D. (2004). Milk-Alkali syndrome: broadening the spectrum of causes to allow early recognition. Internal Medicine Journal, 34(6), 366-NIL_2.
Scopus6 WoS7 Europe PMC62004 Torpy, D., Bachmann, A., Gartside, M., Grice, J., Harris, J., Clifton, P., . . . Whitworth, J. (2004). Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene ALA SER224 polymorphism. Endocrine Research, 30(3), 417-429.
Scopus35 WoS31 Europe PMC232003 Joyner, J. M., Hutley, L. J., Bachmann, A. W., Torpy, D. J., & Prins, J. B. (2003). Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiency. American Journal of Physiology Endocrinology and Metabolism, 284(5 47-5), E1049-E1054.
Scopus23 WoS21 Europe PMC142002 Jackson, R. V., Lafferty, A., Torpy, D. J., & Stratakis, C. (2002). New genetic insights in familial hyperaldosteronism. Annals of the New York Academy of Sciences, 970(1), 77-88.
Scopus44 WoS33 Europe PMC232001 Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Crosbie, G. V., Walters, M. M., . . . Jackson, R. V. (2001). The insulin hypoglycemia test: Hypoglycemic criteria and reproducibility. Journal of Neuroendocrinology, 13(6), 524-530.
Scopus22 WoS20 Europe PMC142001 Torpy, D. J., Bachmann, A. W., Grice, J. E., Fitzgerald, S. P., Phillips, P. J., Whitworth, J. A., & Jackson, R. V. (2001). Familial corticosteroid-binding globulin deficiency due to a novel null mutation: Association with fatigue and relative hypotension. Journal of Clinical Endocrinology and Metabolism, 86(8), 3692-3700.
Scopus104 WoS89 Europe PMC662001 Jackson, R. V., Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Walters, M. M., . . . Whitworth, J. A. (2001). Early rise in blood pressure following administration of adrenocorticotropic hormone-[1-24] in humans. Clinical and Experimental Pharmacology and Physiology, 28(9), 773-775.
Scopus7 WoS6 Europe PMC62001 Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Crosbie, G. V., Walters, M. M., . . . Jackson, R. V. (2001). Adrenocorticotropin stimulation tests in patients with hypothalamic-pituitary disease: Low dose, standard high dose and 8-h infusion tests. Clinical Endocrinology, 55(5), 625-633.
Scopus30 WoS25 Europe PMC192001 Eaton, H. J., Phillips, P. J., Hanieh, A., Cooper, J., Bolt, J., & Torpy, D. J. (2001). Rapid onset of pituitary apoplexy after goserelin implant for prostate cancer: Need for heightened awareness. Internal Medicine Journal, 31(5), 313-314.
Scopus19 WoS15 Europe PMC132000 Lafferty, A. R., Torpy, D. J., Stowasser, M., Taymans, S. E., Lin, J. P., Huggard, P., . . . Stratakis, C. A. (2000). A novel genetic locus for low renin hypertension: Familial hyperaldosteronism type II maps to chromosome 7 (7p22). Journal of Medical Genetics, 37(11), 831-835.
Scopus178 WoS142 Europe PMC1142000 Torpy, D. J., Papanicolaou, D. A., Lotsikas, A. J., Wilder, R. L., Chrousos, G. P., & Pillemer, S. R. (2000). Responses of the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis to interleukin-6: A pilot study in fibromyalgia. Arthritis and Rheumatism, 43(4), 872-880.
Scopus211 WoS168 Europe PMC1272000 Torpy, D. J., Stratakis, C. A., & Chrousos, G. P. (2000). Familial hyperaldosteronism. Brazilian Journal of Medical and Biological Research, 33(10), 1149-1155.
Scopus4 WoS3 Europe PMC32000 Nye, E. J., Bornstein, S. R., Grice, J. E., Tauchnitz, R., Hockings, G. I., Strakosch, C. R., . . . Torpy, D. J. (2000). Interactions between the stimulated hypothalamic-pituitary-adrenal axis and leptin in humans. Journal of Neuroendocrinology, 12(2), 141-145.
Scopus25 WoS23 Europe PMC192000 Hope, P., Turnbull, H., Farr, S., Morley, J., Rice, K., Chrousos, G., . . . Wittert, G. (2000). Peripheral administration of CRF and urocortin: effects on food intake and the HPA axis in the marsupial Sminthopsis crassicaudata. Peptides, 21(5), 669-677.
Scopus36 WoS33 Europe PMC251999 Torpy, D. J., Chen, C. C., Mullen, N., Doppman, J. L., Carrasquillo, J. A., Chrousos, G. P., & Nieman, L. K. (1999). Primary localization of an ectopic ACTH-producing bronchial carcinoid tumor by Indium 111pentetreotide scintigraphy - Authors' response [5]. Journal of Clinical Endocrinology and Metabolism, 84(9), 3402-3403.
1999 Torpy, D. J., Chen, C. C., Mullen, N., Doppman, J. L., Carrasquillo, J. A., Chrousos, G. P., & Nieman, L. K. (1999). Lack of utility of 111In-pentetreotide scintigraphy in localizing ectopic ACTH producing tumors: Follow-up of 18 patients. Journal of Clinical Endocrinology and Metabolism, 84(4), 1186-1192.
Scopus77 WoS64 Europe PMC471999 Torpy, D. J., Bornstein, S. R., Taylor, W., Tauchnitz, R., & Gordon, R. D. (1999). Leptin levels are suppressed in primary aldosteronism. Hormone and Metabolic Research, 31(9), 533-536.
Scopus28 WoS27 Europe PMC211999 Torpy, D. J., Webster, E. L., Zachman, E. K., Aguilera, G., & Chrousos, G. P. (1999). Urocortin and inflammation: Confounding effects of hypotension on measures of inflammation. Neuroimmunomodulation, 6(3), 182-186.
Scopus38 WoS35 Europe PMC261999 Böttner, A., Eisenhofer, G., Torpy, D. J., Ehrhart-Bornstein, M., Keiser, H. R., Chrousos, G. P., & Bornstein, S. R. (1999). Preliminary report: Lack of leptin suppression in response to hypersecretion of catecholamines in pheochromocytoma patients. Metabolism Clinical and Experimental, 48(5), 543-545.
Scopus32 WoS29 Europe PMC131999 Nye, E. J., Hockings, G. I., Grice, J. E., Strakosch, C. R., Torpy, D. J., & Jackson, R. V. (1999). The use of naloxone for investigating disorders of the hypothalamic- pituitary-adrenal axis. Endocrinologist, 9(3), 161-182.
Scopus6 WoS61998 Stratakis, C. A., Kirschner, L. S., Taymans, S. E., Tomlinson, I. P. M., Marsh, D. J., Torpy, D. J., . . . Carney, J. A. (1998). Carney complex, Peutz-Jeghers syndrome, Cowden disease, and Bannayan- Zonana syndrome share cutaneous and endocrine manifestations, but not genetic loci. Journal of Clinical Endocrinology and Metabolism, 83(8), 2972-2976.
Scopus60 WoS43 Europe PMC321998 Joyner, J. M., Grice, J. E., Hockings, G. I., Torpy, D. J., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1998). Inhibition of naloxone-stimulated adrenocorticotropin release by alprazolam in myotonic dystrophy patients. Journal of Neuroendocrinology, 10(5), 391-395.
Scopus7 WoS6 Europe PMC41998 Bornstein, S. R., Webster, E. L., Torpy, D. J., Richman, S. J., Mitsiades, N., Igel, M., . . . Chrousos, G. P. (1998). Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation. Endocrinology, 139(4), 1546-1555.
Scopus104 WoS87 Europe PMC681998 Torpy, D. J., Gordon, R. D., Lin, J. P., Huggard, P. R., Taymans, S. E., Stowasser, M., . . . Stratakis, C. A. (1998). Familial Hyperaldosteronism Type II: Description of a Large Kindred and Exclusion of the Aldosterone Synthase (CYP11B2) Gene<sup>1</sup>. The Journal of Clinical Endocrinology & Metabolism, 83(9), 3214-3218.
1998 Torpy, D. J., & Stratakis, C. A. (1998). Linkage Analysis of Familial Hyperaldosteronism Type II—Absence of Linkage to the Gene Encoding the Angiotensin II Receptor Type 1. The Journal of Clinical Endocrinology & Metabolism, 83(3), 1046.
1998 Buyalos, R. P., Jackson, R. V., Grice, G. I., Hockings, G. I., Torpy, D. J., Fox, L. M., . . . Azziz, R. (1998). Androgen response to hypothalamic-pituitary-adrenal stimulation with naloxone in women with myotonic muscular dystrophy. Journal of Clinical Endocrinology and Metabolism, 83(9), 3219-3224.
Scopus6 WoS7 Europe PMC21998 Torpy, D. J., Bornstein, S. R., & Chrousos, G. P. (1998). Leptin and interleukin-6 in sepsis. Hormone and Metabolic Research, 30(12), 726-729.
Scopus112 WoS95 Europe PMC661998 Taymans, S. E., Pack, S., Pak, E., Torpy, D. J., Zhuang, Z., & Stratakis, C. A. (1998). Human CYP11B2 (aldosterone synthase) maps to chromosome 8q24.3. Journal of Clinical Endocrinology and Metabolism, 83(3), 1033-1036.
Scopus90 WoS70 Europe PMC481998 Torpy, D. J., Tsigos, C., Lotsikas, A. J., Defensor, R., Chrousos, G. P., & Papanicolaou, D. A. (1998). Acute and delayed effects of a single-dose injection of interleukin-6 on thyroid function in healthy humans. Metabolism Clinical and Experimental, 47(10), 1289-1293.
Scopus86 WoS67 Europe PMC521998 Bornstein, S. R., Torpy, D. J., Shek, E. W., Brands, M. W., & Hall, J. E. (1998). Leptin and the renin-angiotensin-aldosterone system [1] (multiple letters). Hypertension, 32(2), 376-377.
Scopus13 WoS14 Europe PMC151998 Torpy, D. J., Bornstein, S. R., Cizza, G., & Chrousos, G. P. (1998). The effects of glucocorticoids on leptin levels in humans may be restricted to acute pharmacologic dosing [1]. Journal of Clinical Endocrinology and Metabolism, 83(5), 1821-1822.
Scopus27 WoS24 Europe PMC211998 Torpy, D. J., Stratakis, C. A., & Gordon, R. D. (1998). Linkage analysis of familial hyperaldosteronism type II - Absence of linkage to the gene encoding the angiotensin II receptor type 1 [6]. Journal of Clinical Endocrinology and Metabolism, 83(3), 1046.
Scopus36 WoS30 Europe PMC251998 Chrousos, G. P., Torpy, D. J., & Gold, P. W. (1998). Interactions between the hypothalamic-pituitary-adrenal axis and the female reproductive system: Clinical implications. Annals of Internal Medicine, 129(3), 229-240.
Scopus607 Europe PMC3941998 Torpy, D. J., Gordon, R. D., Lin, J. P., Huggard, P. R., Taymans, S. E., Stowasser, M., . . . Stratakis, C. A. (1998). Familial hyperaldosteronism type II: Description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene. Journal of Clinical Endocrinology and Metabolism, 83(9), 3214-3218.
Scopus93 WoS70 Europe PMC521997 Webster, E. L., Torpy, D. J., Elenkov, I. J., & Chrousos, G. P. (1997). Corticotropin-releasing hormone and inflammation. Review of Clinical Pharmacology and Pharmacokinetics International Edition, 11(1), 32-39. 1997 Nye, E. J., Hockings, G. I., Grice, J. E., Torpy, D. J., Walters, M. M., Crosbie, G. V., . . . Jackson, R. V. (1997). Aspirin inhibits vasopressin-induced hypothalamic-pituitary-adrenal activity in normal humans. Journal of Clinical Endocrinology and Metabolism, 82(3), 812-817.
Scopus40 WoS37 Europe PMC311997 Torpy, D. J., Papanicolaou, D. A., & Chrousos, G. P. (1997). Sexual dimorphism of the human stress response may be due to estradiol- mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis [1]. Journal of Clinical Endocrinology and Metabolism, 82(3), 982.
Scopus21 WoS17 Europe PMC111997 Torpy, D. J., Stratakis, C. A., & Chrousos, G. P. (1997). Hyper- and Hypoaldosteronism. Vitamins and Hormones, 57(C), 177-216.
Scopus39 WoS22 Europe PMC131997 Torpy, D. J., & Chrousos, G. P. (1997). Stress and critical illness: The integrated immune/hypothalamic- pituitary-adrenal axis response. Journal of Intensive Care Medicine, 12(5), 225-238.
Scopus81997 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1997). Diurnal effects of fluoxetine and naloxone on the human hypothalamic- pituitary-adrenal axis. Clinical and Experimental Pharmacology and Physiology, 24(6), 421-423.
Scopus8 WoS6 Europe PMC31997 Bornstein, S. R., Torpy, D. J., Chrousos, G. P., Licinio, J., & Engelmann, L. (1997). Leptin levels are elevated despite low thyroid hormone levels in the 'euthyroid sick' syndrome [9]. Journal of Clinical Endocrinology and Metabolism, 82(12), 4278-4279.
Scopus21 Europe PMC101997 Torpy, D. J., Papanicolaou, D. A., & Chrousos, G. P. (1997). Sexual Dimorphism of the Human Stress Response May Be Due to Estradiol-Mediated Stimulation of Hypothalamic Corticotropin-Releasing Hormone Synthesis1. The Journal of Clinical Endocrinology & Metabolism, 82(3), 982.
1997 Nye, E. J., Hockings, G. I., Grice, J. E., Torpy, D. J., Walters, M. M., Crosbie, G. V., . . . Jackson, R. V. (1997). Aspirin Inhibits Vasopressin-Induced Hypothalamic-Pituitary-Adrenal Activity in Normal Humans1. The Journal of Clinical Endocrinology & Metabolism, 82(3), 812-817.
1997 Bornstein, S. R., Torpy, D. J., Chrousos, G. P., Licinio, J., & Engelmann, L. (1997). Leptin levels are elevated despite low thyroid hormone levels in the "euthyroid sick" syndrome. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 82(12), 4278-4279.
WoS131996 Webster, E. L., Lewis, D. B., Torpy, D. J., Zachman, E. K., Rice, K. C., & Chrousos, G. P. (1996). In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral inflammation. Endocrinology, 137(12), 5747-5750.
Scopus291 WoS279 Europe PMC2051996 Papanicolaou, O. A., Tsigos, C., Torpy, D., Defensor, R., Thompson, B., & Chrousos, O. P. (1996). Recombinant interleukin-6 effects on pituitary secretion in humans. Journal of Investigative Medicine, 44(3), 266.
Scopus81996 Torpy, D. J., & Chrousos, G. P. (1996). The three-way interactions between the hypothalamic-pituitary-adrenal and gonadal axes and the immune system. Bailliere S Clinical Rheumatology, 10(2), 181-198.
Scopus70 WoS52 Europe PMC371995 Torpy, D. J., Grice, J. E., Hockings, G. I., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1995). EFFECT OF SODIUM VALPROATE ON NALOXONE‐STIMULATED ACTH AND CORTISOL RELEASE IN HUMANS. Clinical and Experimental Pharmacology and Physiology, 22(6-7), 441-443.
Scopus12 WoS13 Europe PMC21995 Torpy, D. J., Grice, J. E., Hockings, G. I., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1995). The effect of desipramine on basal and naloxone-stimulated cortisol secretion in humans: Interaction of two drugs acting on noradrenergic control of adrenocorticotropin secretion. Journal of Clinical Endocrinology and Metabolism, 80(3), 802-806.
Scopus15 WoS14 Europe PMC91995 Grice, J. E., Jackson, R. V., Hockings, G. I., Torpy, D. J., Walters, M. M., & Crosbie, G. V. (1995). Adrenocorticotropin hyperresponse to the corticotropin-releasing hormone-mediated stimulus of naloxone in patients with myotonic dystrophy. Journal of Clinical Endocrinology and Metabolism, 80(1), 179-184.
Scopus17 WoS17 Europe PMC81995 Jackson, R. V., Grice, J. E., Hockings, G. I., & Torpy, D. J. (1995). Naloxone-induced ACTH release: Mechanism of action in humans. Clinical Endocrinology, 43(4), 423-424.
Scopus18 WoS16 Europe PMC121995 Hlockings, G. I., Grice, J. E., Watters, M. M., Crosbie, G. V., Torpy, D. J., & Jackson, R. V. (1995). A synergistic adrenocorticotropin response to naloxone and vasopressin in normal humans: Evidence that naloxone stimulates endogenous corticotropin-releasing hormone. Neuroendocrinology, 61(2), 198-206.
Scopus21 WoS22 Europe PMC91994 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1994). Alprazolam attenuates vasopressin-stimulated adrenocorticotropin and cortisol release: Evidence for synergy between vasopressin and corticotropin-releasing hormone in humans. Journal of Clinical Endocrinology and Metabolism, 79(1), 140-144.
Scopus45 WoS41 Europe PMC281994 Torpy, D. J., Jackson, R. V., Grice, J. E., Hockings, G. I., Crosbie, G. V., & Walters, M. M. (1994). EFFECT OF FLUMAZENIL ON BASAL AND NALOXONE‐STIMULATED ACTH AND CORTISOL RELEASE IN HUMANS. Clinical and Experimental Pharmacology and Physiology, 21(2), 157-161.
Scopus2 WoS11994 Hockings, G. I., Jackson, R. V., Grice, J. E., Crosbie, G. V., Walters, M. M., Torpy, D. J., & Jackson, A. J. (1994). Paradoxical inhibition by aspirin of naloxone-induced adrenocorticotropin secretion in myotonic dystrophy. Journal of Clinical Endocrinology and Metabolism, 78(6), 1424-1427.
Scopus6 WoS6 Europe PMC41993 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1993). Alprazolam blocks the naloxone-stimulated hypothalamo-pituitary-adrenal axis in man. Journal of Clinical Endocrinology and Metabolism, 76(2), 388-391.
Scopus63 WoS63 Europe PMC361993 Torpy, D. J., Jackson, R. V., Grice, J. E., Hockings, G. I., Strakosch, C. R., & Topliss, D. J. (1993). NALOXONE STIMULATION OF ACTH SECRETION DURING PETROSAL SINUS SAMPLING IN CUSHING'S SYNDROME. Clinical and Experimental Pharmacology and Physiology, 20(5), 299-302.
Scopus10 WoS11 Europe PMC4- Clarke, B., Kireta, S., Johnston, J., Christou, C., Greenwood, J., Hurtado, P., . . . Torpy, D. (n.d.). Supplementary data for "In vivo formation of adrenal organoids in a novel porcine model of adrenocortical cell transplantation".
- Coates, P., Penko, D., Nitschke, J., Johnson, J., Kireta, S., Concannon, E., . . . Drogemuller, C. (2025). The Proof of Concept INCEPTR trial 12 month outcomes - Intracutaneous islet transplant in humans into pre-vascularised Novosorb® neodermis. Endocrine Abstracts.
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Book Chapters
Year Citation 2022 Torpy, D. J., O’Reilly, M. W., & De Sousa, S. M. C. (2022). Adrenal Disease in Pregnancy. In J. A. H. Wass, W. Arlt, & R. K. Semple (Eds.), Oxford Textbook of Endocrinology and Diabetes 3e (pp. 1479-1488). Oxford University PressOxford.
DOI2012 Marathe, C., & Torpy, D. (2012). Corticosteroid-Binding Globulin Gene Mutations and Chronic Fatigue/Pain Syndromes: An Overview of Current Evidence. In C. R. Snell (Ed.), An International Perspective on the Future of Research in Chronic Fatigue Syndrome. 2011 Torpy, D. (2011). A woman with palpitations.. In P. Devitt, J. Mitchell, & C. Hamilton Craig (Eds.), Clinical Problems in Medicine and Surgery E-Book (3rd ed., pp. 336-342). Elsevier Health Sciences. 2003 Stergiopoulos, S. G., Torpy, D. J., & Stratakis, C. A. (2003). Primary aldosteronism: Pathophysiology, diagnosis and management. In Endocrine Surgery (pp. 401-410). 2001 Torpy, D., & Jackson, R. V. (2001). Adrenocorticotropin - physiology and clinical aspects.. In K. L. Becker (Ed.), Principles and Practice of Endocrinology and Metabolism (3rd ed., pp. 153-159). Lippincott Williams & Wilkins. 1999 Ratnaike, R. N., Buttery, J. E., & Torpy, D. (1999). Endocrine, metabolic and miscellaneous causes of diarrhoea.. In R. N. Ratnaike (Ed.), Diarrhoea and Constipation in Geriatric Practice (pp. 171-184). Cambridge University Press. 1997 Torpy, D., & Chrousos, G. P. (1997). The general adaptation syndrome: an overview.. In K. P. Ober (Ed.), Endocrinology of Critical Disease (pp. 1-24). Humana Press. -
Conference Papers
Year Citation 2023 Wu, D., Rushworth, L., Torpy, D. J., & Coates, P. T. H. (2023). Chronic Pancreatitis in children under 18 in New South Wales, Australia: establishing suitable candidates for total pancreatectomy and islet auto transplantation (TPIAT). In TRANSPLANTATION Vol. 107 (pp. 189). CA, San Diego: LIPPINCOTT WILLIAMS & WILKINS.
DOI2018 De Sousa, S. M. C., McCormack, A. I., McGrath, S., & Torpy, D. J. (2018). Use of prolactin in inferior petrosal sinus sampling is misleading. In CLINICAL ENDOCRINOLOGY Vol. 89 (pp. 32). Perth, AUSTRALIA: WILEY.
WoS12016 Nenke, M. A., Holmes, M., Rankin, W., Lewis, J. G., & Torpy, D. J. (2016). Paradoxical reduction in corticosteroid-binding globulin cleavage is seen in alpha-1 antitrypsin deficiency: implications for cortisol homeostasis. In CLINICAL ENDOCRINOLOGY Vol. 84 (pp. 41). Adelaide, AUSTRALIA: WILEY. 2016 Hodyl, N. A., Stark, M. J., Nenke, M. A., Lewis, J. G., & Torpy, D. J. (2016). Displacement of Cortisol from Corticosteroid-Binding Globulin by High Fetal Progesterone May Drive Free Fetal Cortisol.. In REPRODUCTIVE SCIENCES Vol. 23 (pp. 310A). Montreal, CANADA: SAGE PUBLICATIONS INC. 2016 Hue, S. M., Torpy, D. J., Bennett, G., Kay, T. W., Thomas, H. E., Goodman, D., . . . Coates, P. T. (2016). De-novo donor-specific anti-HLA antibodies in islet cell transplant recipients in Australia. In TRANSPLANTATION Vol. 100 (pp. S405). LIPPINCOTT WILLIAMS & WILKINS. 2015 O'Connell, P., Holmes-Walker, D. J., Goodman, D., Hawthorne, W. J., Loudovaris, T., Gunton, J. E., . . . Kay, T. W. (2015). Five years outcomes from the Australian multicentre trial of islet transplantation. In XENOTRANSPLANTATION Vol. 22 (pp. S10-S11). Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2015 Drogemuller, C., Radford, T. M., Torpy, D. J., Rainis, H. A., Barton, F. B., & Coates, P. T. (2015). Effects of etanercept route of administration in clinical allogeneic islet transplantation: an analysis from the collaborative islet transplant registry (CITR). In XENOTRANSPLANTATION Vol. 22 (pp. S187-S188). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
WoS22015 O'Connell, P. J., Holmes-Walker, D. J., Goodman, D., Hawthorne, W. J., Loudovaris, T., Gunton, J. E., . . . Kay, T. W. (2015). FIVE YEARS OUTCOMES FROM THE AUSTRALIAN MULTICENTRE TRIAL OF ISLET TRANSPLANTATION.. In TRANSPLANTATION Vol. 99 (pp. S17). Melbourne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS. 2015 Drogemuller, C., Radford, T. M., Torpy, D. J., Rainis, H. A., Barton, F. B., & Coates, P. T. (2015). EFFECTS OF ETANERCEPT ROUTE OF ADMINISTRATION IN CLINICAL ALLOGENEIC ISLET TRANSPLANTATION: AN ANALYSIS FROM THE COLLABORATIVE ISLET TRANSPLANT REGISTRY (CITR).. In TRANSPLANTATION Vol. 99 (pp. S313). Melbourne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS. 2010 Ho, J. T., O'Connor, S., Chapman, M. J., Edwards, J., Lam, S., Ludbrook, G., . . . Torpy, D. J. (2010). Plasma NOx Is Not a Suitable Tissue Marker To Guide Glucocorticoid Therapy in Severe Sepsis.. In ENDOCRINE REVIEWS Vol. 31 (pp. 1 page). San Diego, CA: ENDOCRINE SOC. 2010 Jung, C., Ho, J. T., Torpy, D. J., Lewis, J. G., & Inder, W. J. (2010). A Longitudinal Study of Plasma and Urinary Cortisol in Pregnancy and the Post-Partum Period.. In ENDOCRINE REVIEWS Vol. 31 (pp. 1 page). San Diego, CA: ENDOCRINE SOC. 2007 Torpy, D. J., & Ho, J. T. (2007). Value of free cortisol measurement in systemic infection. In Hormone and Metabolic Research Vol. 39 (pp. 439-444). Bethesda, MD: GEORG THIEME VERLAG KG.
DOI Scopus36 WoS34 Europe PMC252002 Torpy, D. J., Mullen, N., Ilias, I., & Nieman, L. K. (2002). Association of hypertension and hypokalemia with Cushing's syndrome caused by ectopic ACTH secretion: A series of 58 cases. In K. Pacak, & G. Eisenhofer (Eds.), Annals of the New York Academy of Sciences Vol. 970 (pp. 134-144). BETHESDA, MARYLAND: NEW YORK ACAD SCIENCES.
DOI Scopus154 WoS121 Europe PMC961999 Elenkov, I. J., Webster, E. L., Torpy, D. J., & Chrousos, G. P. (1999). Stress, corticotropin-releasing hormone, glucocorticoids, and the immune/inflammatory response: Acute and chronic effects. In M. Cutolo, A. T. Masi, J. W. J. Bijlsma, I. C. Chikanza, H. L. Bradlow, & L. Castagnetta (Eds.), Annals of the New York Academy of Sciences Vol. 876 (pp. 1-13). GENOA, ITALY: NEW YORK ACAD SCIENCES.
DOI Scopus215 WoS180 Europe PMC1221999 Lafferty, A. R., Torpy, D. J., Huggard, P., Gordon, R. D., & Stratakis, C. A. (1999). Familial hyperaldosteronism type II: Identification of potential disease loci using linkage analysis. In PEDIATRIC RESEARCH Vol. 45 (pp. 92A). INT PEDIATRIC RESEARCH FOUNDATION, INC. 1998 Grice, J. E., Torpy, D. J., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1998). Pituitary-adrenal responses to combined oral D-fenfluramine and intravenous naloxone in humans. In Clinical and Experimental Pharmacology and Physiology Vol. 25 (pp. 621-623). FREMANTLE, AUSTRALIA: BLACKWELL SCIENCE.
DOI Scopus2 WoS2 Europe PMC21998 Webster, E. L., Torpy, D. J., Elenkov, I. J., & Chrousos, G. P. (1998). Corticotropin-releasing hormone and inflammation. In S. M. McCann, J. M. Lipton, E. M. Sternberg, G. P. Chrousos, P. W. Gold, & C. C. Smith (Eds.), Annals of the New York Academy of Sciences Vol. 840 (pp. 21-32). BETHESDA, MARYLAND: NEW YORK ACAD SCIENCES.
DOI Scopus157 WoS142 Europe PMC861996 Jackson, R. V., Hockings, G. I., Torpy, D. J., Grice, J. E., Crosbie, G. V., Walters, M. M., & Strakosch, C. R. (1996). New diagnostic tests for Cushing's syndrome: Uses of naloxone, vasopressin and alprazolam. In Clinical and Experimental Pharmacology and Physiology Vol. 23 (pp. 579-581). Australia: WILEY.
DOI Scopus5 WoS5 Europe PMC21990 BANNISTER, K. M., GAFFNEY, R., & TORPY, D. J. (1990). REDUCING THE FALSE NEGATIVE RATE OF RADIONUCLIDE SCANS IN RENAL-ARTERY STENOSIS (RAS) - THE VALUE OF CAPTOPRIL. In KIDNEY INTERNATIONAL Vol. 38 (pp. 544). BLACKWELL SCIENCE INC. -
Conference Items
Year Citation 2023 Wu, D., Zuiani, J., Drogemuller, C., De Sousa, S., Adelson, D., Torpy, D. J., & Coates, P. T. H. (2023). The Epidemiology of Hereditary Pancreatitis in Australia and its effect on patient of Total Pancreatectomy with Islet Auto-Transplantation (TPIAT). Poster session presented at the meeting of Abstracts of the IPITA-IXA-CTRMS Joint Congress 2023, as published in Transplantation. San Diego, CA, USA: Lippincott Williams & Wilkins.
DOI2019 Baranoff, J., Saranapala, M., Burke, A. L., Collins, K., & Torpy, D. (2019). Acceptability, credibility, and effectiveness of group-based cognitive behavioral stress management (CBSM) during diet-induced weight loss. Poster session presented at the meeting of 'Applying New Solutions in Health Psychology’ 2019 APS College of Health Psychologists Conference. Stamford Grand Hotel, Glenelg, South Australia. 2017 De Sousa, S. M. C., Chapman, I. M., Falhammar, H., & Torpy, D. J. (2017). Dopa-testotoxicosis: a novel drug toxicity of dopamine agonists in male prolactinoma patients. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2017 De Sousa, S. M. C., Stowasser, M., Feng, J., Schreiber, A. W., Hahn, C. N., Torpy, D. J., . . . Scott, H. S. (2017). Sequence variants in <i>ARMC5</i> are not implicated in familial hyperaldosteronism type II. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2017 Meyer, E. J., De Sousa, S. M. C., Burt, M. G., & Torpy, D. J. (2017). Cavernous internal carotid artery ansurysm: a rare cause of marked hyperprolactinaemia. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2014 Gagliardi, L., Nenke, M. A., Thynne, T. R. J., von der Borch, J., Rankin, W. A., Henley, D. E., . . . Torpy, D. J. (2014). Continuous Subcutaneous Hydrocortisone Infusion Therapy in Addison's Disease; Effects on Health Status in a Randomised Placebo-Controlled Clinical Trial. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC. 2014 Gagliardi, L., Nenke, M. A., Thynne, T. R. J., von der Borch, J., Rankin, W. A., Henley, D. E., . . . Torpy, D. J. (2014). Continuous Subcutaneous Hydrocortisone Infusion Therapy in Addison's Disease; Effects on Health Status in a Randomised Placebo Controlled Clinical Trial. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC. 2012 Marathe, C., Irish, G., & Torpy, D. (2012). The clinical outcome of pituitary adenomas in the cavernous sinus. Poster session presented at the meeting of Endocrine. Florence, Italy. -
Report for External Bodies
Year Citation 2008 Bassett, D., Edwards-Smith, C., Goldney, R., Beltrame, J. F., Riessen, R., Torpy, D., . . . Wilson, D. (2008). The Management of Cardiometabolic Effects in Patients Receiving Antipsychotic Medications.
Grants
| 2011 | ACTH-independent macronodular adrenal hyperplasia. | Royal Adelaide Hospital Research Grant. | Gagliardi L, Scott H, Torpy DJ, Hahn C. | $25,000 |
| 2012 | A randomized placebo controlled crossover pilot study of cortisol replacement in chronic pain patients. | Royal Adelaide Hospital Clinical Research Grant. | Torpy DJ, Rolan P. | $30,000 |
| 2013 | Effect of depletion of cleaved CBG on inflammation in preeclampsia, rheumatoid arthritis and sepsis. | Royal Adelaide Hospital Research Grant. | Nenke M, Lewis J, Torpy DJ. | $50,000 |
| 2015 | Obesity, Stress and the Metebolic Syndrome: Effect of cognitive behavior stress management (CBSM) on the extent and durability of diet-induced weight loss. Role of the biological stress system. | Flinders Medical Centre (FMC) Foundation. Seeding Grant. | Licinio J, Torpy DJ. | $15,000 |
| 2015 | Effect of plasma corticosteroid binding globulin on noradrenaline weaning in septic shock. | RAH Research Grant. | $40,000 | |
| 2016 | High-affinity corticosteroid binding globulin depletion in septic shock: clinical implications | NHMRC Near Miss grant. RAH Special purposes fund. | $40,000 | |
| 2019 | Adrenal cell transplantation for Addison’s disease using biodegradable temporizing matrix technology. | RRC Clinical Project Grant. | Torpy, DJ | $48,000 |
| 2020 | Development of new approaches to measure proteolysis and glycosylation profiling of high and low affinity corticosteroid-binding globulin (CBG) in septic shock using mass spectrometry. | RRC Clinical Project Grant. | $47,840 | |
| 2020 | Purification of CBG for glycosylation analysis in sepsis and distribution studies | Near Miss Funding | $50,000/FHMS $30,511/SAHMRI $19,489 |
Teaching
In addition to the teaching activities below, Prof. Torpy has supervised 11 HDR students to completion from 2001-2021 and currently supervises 5 HDR students.
Undergraduate:
| 1988 – 1991 | Bedside teaching and small group tutorials to undergraduate medical students at the Universities of Adelaide and Queensland in my capacities as Senior Medical Registrar. |
| 1992 – 1995 | Clinical Instructor in Medicine |
| 1998 | Clinical Senior Lecturer in Medicine |
| 1997 – 1998 | Teaching in the field of clinical endocrinology at the National Institutes of Health, USA. Supervision of junior scientific staff in specific laboratory procedures at the NIH. |
| 1997 - 1998 | Lecturer in Endocrinology – MBBS Course Year 2. Includes provision of web-based learning materials. |
| 2000 – 2001 | Supervision of foreign elective students in endocrinology – clinical and research, through postgraduate Medical Education Association of Queensland. |
| 2000 - 2001 |
Problem Based Learning Tutor, Graduate Medical Course, University of Queensland. Provision of case wraps / end core based learning in endocrine related cases University of Adelaide Year 4 students. |
| 2002- | Group based tutorials University of Adelaide Year 4 students diabetes topics. |
Postgraduate:
| 1998 - 1999 | Responsibilities for coordinating an internal medicine training program for basic physician trainees. |
| 2000 – 2001 | Co-supervision of RACP advanced trainees in endocrinology (core year). |
| 2002 – 2012 | Provision of endocrinology tutorials for basic physician trainees. |
| 2002 – 2012 | Supervision of RACP advanced trainees in endocrinology (required year). |
| 2002 - 2012 | Participation in postgraduate teaching of advanced trainees, weekly long cases, and trial exam program. |
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2025 Co-Supervisor Novel applications of molecular imaging and theranostics in endocrine neoplasia. Doctor of Philosophy Doctorate Part Time Mr James Michael McNeil 2025 Co-Supervisor Harnessing a native corticosteroid-binding globulin to treat chronic inflammation and life-threatening septic shock Doctor of Philosophy Doctorate Full Time Mr Declan Emmett Kilgariff 2023 Co-Supervisor Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock Master of Clinical Science Master Part Time Mr Benjamin James Young -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 - 2024 Co-Supervisor Understanding the Relationship of Incretin Hormones, Gastric Emptying and the Glucoregulatory Responses to Nutrients Doctor of Philosophy Doctorate Full Time Dr Ryan Joseph Jalleh 2019 - 2025 Principal Supervisor Exploring Adrenocortical Cell Transplantation for Primary Adrenal Insufficiency Doctor of Philosophy Doctorate Full Time Dr Brigette Marie Clarke 2017 - 2022 Principal Supervisor Corticosteroid-Binding Globulin in Inflammation and Septic Shock Doctor of Philosophy Doctorate Full Time Dr Emily Jane Meyer 2016 - 2020 Principal Supervisor Clinical and Genetic Aspects of Prolactin Hypersecretion Doctor of Philosophy Doctorate Full Time APrf Sunita Maria Christina De Sousa 2015 - 2017 Co-Supervisor The Effect of Dairy 0n Insulin Sensitivity Master of Philosophy (Medical Science) Master Full Time Jordan Linley Peters 2014 - 2017 Principal Supervisor Corticosteroid-Binding Globulin – a Targeted Delivery System for Cortisol. Physiology and Responses to Acute and Chronic Inflammation Doctor of Philosophy Doctorate Full Time Dr Marni Anne Nenke 2010 - 2013 Co-Supervisor Neuro-endocrine Function in Older Men with Chronic Pain - Effects of Chronic Opioid Usage Master of Medical Science Master Part Time Ms Clare Haylock 2010 - 2015 Co-Supervisor Tri-iodothyronine (T3) Therapy in a Pre-Clinical Model of Septic Shock Doctor of Philosophy Doctorate Full Time Dr Matthew Jerome Maiden 2008 - 2011 Principal Supervisor Regulation of Cortisol Secretion in Humans; Relation to Vasopressin Action at the Adrenals in Macronodular and Micronodular Adrenocortical Tumours and Well-Being in Addison's Disease Doctor of Philosophy Doctorate Full Time Dr Lucia Gagliardi 2004 - 2007 Principal Supervisor Nutrition and Vascular Function Doctor of Philosophy Doctorate Full Time Jennifer Beatrice Keogh 2004 - 2007 Principal Supervisor Corticosteroid Binding Globulin: High Resolution Separation of Glycan Isoforms from Plasma of Pregnant Women and Women taking the Combined Oral Contraceptive Pill Master of Medical Science Master Full Time Miss Elizabeth Mitchell 2004 - 2007 Principal Supervisor Cortisol and Blood Pressure Perturbation in the Pathophysiology of Septicaemia, Complicated Pregnancy and Weight Loss/Obesity Doctor of Philosophy Doctorate Full Time Dr Jui Ho -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2011 - 2014 Co-Supervisor The effects of dietary salt restriction and potassium augmentation on diabetes mellitus and hypertension University of South Australia Doctor of Philosophy Doctorate Full Time Kristina Petersen
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Committee Memberships
Date Role Committee Institution Country 2010 - 2012 Chair Organising Committee Annual Endocrine Clinical Education Weekend Update (SA). Australia 2009 - 2012 Member Program Organising Committee Endocrine Society of Australia Annual Scientific Meeting Australia -
Memberships
Date Role Membership Country 2003 - ongoing Member Hanson Institute of Medical Research Australia 1994 - ongoing Member The Endocrine Society (US) United States 1991 - ongoing Member Fellow of the Royal Australasian College of Physicians Australia 1990 - ongoing Member Endocrine Society of Australia Australia 1984 - ongoing Member Australian Medical Association Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2016 - ongoing Board Member Journal of the Endocrine Society Oxford University Press United Kingdom 2011 - 2016 Associate Editor Journal of Clinical Endocrinology and Metabolism Oxford University Press United Kingdom 2010 - 2014 Board Member Hormone and Metabolic Research Thieme India -
Review, Assessment, Editorial and Advice
Date Title Type Institution Country 2012 - 2012 Cancer Grant Reviewer Grant Assessment Pfizer Australia 2009 - 2012 Abstract reviewer Conference Review Endocrine Society of Australia Annual Scientific Meeting Australia 2001 - ongoing Grant reviewer Grant Assessment National Heart Foundation Australia 2000 - 2000 Grant reviewer Grant Assessment Canterbury Medical Research Foundation, University of Otago New Zealand 1999 - 1999 Grant reviewer Grant Assessment The Royal Adelaide Hospital Project Grant Committee Australia 1998 - 2018 Abstract reviewer Conference Review The Endocrine Society (US) Annual Scientific Meeting United States 1997 - ongoing Grant reviewer Grant Assessment National Health and Medical Research Council Australia
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