Dr Abiodun Ogunniyi
NHMRC Externally-Funded Research Associate Professor
School of Animal and Veterinary Sciences
College of Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
My research program broadly aims to gain a deep understanding of how bacterial pathogens interact with their hosts to cause disease. I then apply the information gleaned from such investigations to prevent or treat the infections through vaccination or using new antimicrobial agents and novel biocides. I also integrate food safety, environmental, human and animal health research as a “One Health” approach to managing infections caused by multidrug-resistant pathogens (superbugs) through antimicrobial stewardship, for better public health outcomes. To achieve these objectives, I use a combination of molecular, cellular and immunological techniques and imaging of light-emitting microorganisms during infection in living mice (in vivo bioluminescence imaging).
I have a keen interest in understanding the molecular mechanisms of bacterial pathogenesis, with emphasis on the characterisation of virulence factors and evaluating the potential of candidate vaccine antigens. My PhD was conducted under the joint supervision of Professor Paul Manning, Professor Ieva Kotlarski, and Associate Professor Renato Morona and entailed the functional characterisation of the SefA protein of Salmonella enterica serovar Enteritidis.
I carried out my postdoctoral work in Professor James Paton’s laboratory from March 1997 to December 2009 on the molecular analysis of pneumococcal pathogenesis, and became an independent Senior Research Fellow in January 2010.
I joined the Australian Centre for Antimicrobial Resistance Ecology (ACARE; Director - Prof Darren Trott) in January 2015, where my research focusses on efficacy assessments of new broad-spectrum antimicrobials to address the rising incidence of multidrug-resistant bacterial pathogens. I also assess efficacy evaluation of biocides (such as the pH-neutral electrolysed oxidising water) for wide application in health, agriculture and food industries.
Throughout my research career, I have contributed significantly to the design and execution of research projects, international research grant applications and development of new technologies. I have significantly harnessed my expertise and experience to supervise and mentor numerous Honours, MSc and PhD candidates, and I actively collaborate with national and international colleagues and postdoctoral fellows to achieve mutual success in our research activities.
A significant aspect of my research also involves extensive engagement and consultation with Industry to promote research translation into community benefit through commercialisation.
I have a series of interwoven projects in my research program:
Molecular analysis of bacterial pathogenesis
Efficacy evaluation of new biocides
Serotype-independent pneumococcal vaccines
| Date | Position | Institution name |
|---|---|---|
| 2024 - ongoing | Associate Professor | The University of Adelaide |
| 2023 - 2028 | Chief Investigator | The University of Adelaide |
| 2023 - 2026 | NHMRC Externally-Funded Research Fellow | The University of Adelaide |
| 2022 - ongoing | Group leader, novel drug discovery and preclinical evaluation program | The University of Adelaide |
| 2017 - 2020 | Senior Research Fellow (C) | University of South Australia |
| 2015 - 2023 | University Senior Postdoctoral Researcher (C) | The University of Adelaide |
| 2010 - 2014 | Senior Research Fellow (C) | The University of Adelaide |
| 2001 - 2009 | Senior Research Officer (B) | Women's and Children's Hospital and The University of Adelaide |
| 1997 - 2000 | Research Officer (A) | Women's and Children's Hospital |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2024 | Award | ASA 2024 Travel Award | Australian Society for Antimicrobials | Australia | AU$2,500.00 |
| 2022 | Fellowship | Fellow, Australian Society for Microbiology (FASM) | The Australian Society for Microbiology | Australia | - |
| 2012 | Achievement | Research Career Development Network (RCDN) Achievement Award | The University of Adelaide | Australia | - |
| 2007 | Award | Research Career Development Network (RCDN) Travel Award | The University of Adelaide | Australia | - |
| 1991 | Scholarship | Equity and Merit Scholarship Award | Australian International Development Assistance Bureau (AIDAB, now Australian Agency for International Development [AusAID]) | Australia | - |
| Language | Competency |
|---|---|
| English | Can read, write, speak, understand spoken and peer review |
| Yoruba | Can read, write, speak and understand spoken |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 1991 - 1996 | The University of Adelaide | Australia | PhD |
| 1987 - 1989 | Obafemi Awolowo University | Nigeria | MSc |
| 1982 - 1986 | University of Jos | Nigeria | BSc (First Class Honours) |
| Date | Title | Institution name | Country |
|---|---|---|---|
| 2022 | Fellow, The Australian Society for Microbiology (FASM) | The Australian Society for Microbiology (ASM) | Australia |
| Year | Citation |
|---|---|
| 2015 | Knippenberg, S., Ueberberg, B., Maus, R., Bohling, J., Ding, N., Tarres, M. T., . . . Maus, U. A. (2015). Streptococcus Pneumoniae Triggers Progression Of Pulmonary Fibrosis Through Pneumolysin. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 191 (pp. 1 page). Denver, CO: AMER THORACIC SOC. |
| Year | Citation |
|---|---|
| 2017 | Pi, H., Khazandi, M., Ogunniyi, A. D., Page, S. W., Venter, H., & Trott, D. J. (2017). Characterization of a potential newclass of antimicrobial agent for Gram-negative bacteria. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. Taipei, TAIWAN: ELSEVIER SCIENCE BV. |
| 2016 | Kopecki, Z., Ogunniyi, A. D., Trott, D., & Cowin, A. J. (2016). Development of novel bioluminescent models of wound infection. Poster session presented at the meeting of Wound repair and regeneration. US: Wiley-Blackwell Publishing. DOI |
| 2011 | Weber, M., Lambeck, S., Ding, N., Henken, S., Kohl, M., Deigner, H. P., . . . Bauer, M. (2011). Hepatic Induction of Cholesterol Biosynthesis Reflects a Remote Adaptive Response to Pneumococcal Pneumonia. Poster session presented at the meeting of INFECTION. SPRINGER HEIDELBERG. |
| Year | Citation |
|---|---|
| 2007 | Steinhoff, M. C. (2007). Animal models for protein pneumococcal vaccine evaluation: A summary. Elsevier BV. DOI |
| Year | Citation |
|---|---|
| 2016 | Alsharifi, M., Babb, R., Chen, A. Y., David, S. C., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). 050231, Streptococcal Vaccine. Australia. |
| 2016 | Alsharifi, M., Babb, R., Chen, A. Y., David, S. C., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). 050231, Streptococcal Vaccine. Australia. |
| 2016 | Babb, R., Alsharifi, M., Chen, A. Y., David, S. C., Hurst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). WO2016149771, Streptococcal vaccine. |
| 2016 | Babb, R., Alsharifi, M., Chen, A. Y., David, S. C., Hurst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). WO2016149771, Streptococcal vaccine. |
| 2013 | Paton, J., Mahdi, L., & Ogunniyi, A. (2013). WO2013040648, Pneumococcal GLPO immunogen. |
| 2011 | Rhee, D. K., Kwon, H. Y., Choi, M. H., Ogunniyi, A. D., & Paton, J. C. (2011). JP4646806, Vaccine comprising a recombinant S. pneumoniae ClpP protein. |
| 2005 | Rhee, D., Kwon, H., Choi, M., Ogunniyi, A., & Paton, J. (2005). WO/2005/063283, Vaccine comprising recombinant CIpP protein of streptococcus Pneumoniae. Korea. |
| Funding Scheme | CI/PI/AI Names | Amount Funded | Years of Funding | Project Title |
| NHMRC Ideas Grant (APP2020758) | Ogunniyi A, Garg S, Woolford L, Soares da Costa T | $981,046 | 2023-2025 | A novel dual therapy approach to treatment of multidrug-resistant Gram-negative infections |
| IC220100050: ARC Industrial Transformation Training Centre (ARC ITTC) | Blaskovich M (CI) Trott D (CI), Henderson I (CI) Amirali Popat A (CI), Guo J (CI) Elliott A (CI), Soares Magalhaes R (CI), Turni C (CI), Wilson D (CI), Ogunniyi A (CI), Soares da Costa T (CI), Parekh H (CI), Ziora Z (CI), De Cerqueira G (PI), Page S (PI), van Merkestein R (PI), Boot-Handford M (PI), Sceats M (PI), Bright M (PI), Chandrasekaran N (PI) | $4,508,426 | 2023-2027 | ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR) |
| Contract Research (UA227512); Contracting Party: Invion Limited and RMWC Unlimited Innovation Pty Ltd | Ogunniyi AD (CI) Trott DJ (CI) |
$74,019 PLUS Contract Variation 1 ($50,713) |
2022-2023 | Evaluation of the in vitro antimicrobial activity of 5 photodynamic therapy compounds against Gram-positive, Gram-negative (including periodontitis-causing bacteria) and fungal pathogens. |
| Research Roadmap Grant Scheme 2021, Faculty of Sciences, The University of Adelaide | Wilson DW (CI), O’Handley R (CI), Richter K (CI), Gancheva MR (CI), Ogunniyi AD (CI), Sheppard AE (CI), Ebrahimie E (CI), Abraham R (CI), Trott DJ (CI) | $37,000 | 2022 | Deciphering the mechanism of action of a new class of cell membrane-active antimicrobials: a pathway to widespread applications in human and animal health |
| ICERA DSTG To Neoculi Pty Ltd | Page SW (CI), Trott D (CI), Garg S (CI), Ogunniyi AD (CI) | $339,963 | 2021-2022 | Tier 2 Priority: Enhanced Human Performance – Operating in CBRN Environments |
| Contract Research (UA216024); Contracting Party: Zoetis Indonesia | Ogunniyi AD (CI) | $32,556 | 2021 | Zoetis Lincospectin Checkerboard / FIC studies |
| Contract Research Variation 1 (UA194233-S02); Contracting Party: Botanix Pharmaceuticals Ltd | Ogunniyi AD (CI) | $42,594 | 2019 | Cannabidiol MIC and MBC against clinical isolates of canine otitis externa in Australia and time-kill assay against Staphylococcus aureus ATCC 29213 |
| Contract Research (UA194233); Contracting Party: Botanix Pharmaceuticals Ltd | Ogunniyi AD (CI) | $19,546 | 2019 | Efficacy testing of synthetic cannabidiol in a bioluminescent murine model of Staphylococcus aureus scald wound infection |
| Contract Research (UA172503); Contracting Party: The University of Queensland | Trott D (CI); Ogunniyi AD (CI) | $12,000 | 2018 | Efficacy trials of MCC5145 against S. pneumoniae D39 bacteraemia using a bioluminescent intraperitoneal mouse model of sepsis |
| Contract Research (UA172408); Contracting Party: CSIRO | Trott D (CI); Ogunniyi AD (CI) | $33,150 | 2018 | Literature Review on the presence of antimicrobial resistance (AMR) in food in Australia and New Zealand |
| Contract Research (UA183243-S01); Contracting Party: Bayer Australia Ltd | Trott D (CI); Ogunniyi AD (CI) | $47,911 | 2018 | Mastitis Product Registration (benzyl penicillin) MIC Study |
| DEBRA Australia | Kopecki Z (CI), Cowin A (CI), Vasilev K (CI), Ogunniyi AD (CI) | $40,000 | 2018 | Safe and intelligent dressings for treatment of infected wounds |
| Research Themes Investment Scheme (101796) Seed Funding, University of South Australia | Thomas N (CI), Prestidge C (CI), Ogunniyi AD (CI), Kopecki Z (CI), Cowin A (CI), Wormald PJ (PI) | $40,000 | 2018 | Re-sensitising resistant bacteria against antibiotics: Giving new power to failing medicines. |
| Research Themes Investment Scheme, University of South Australia | Kopecki Z (CI), Cowin A (CI), Venter H (CI), Garg, S (CI), Coad B (CI) Page, S (PI), Trott D (CI), Ogunniyi AD (PI) | $40,000 | 2018 | New in vivo technologies for preclinical assessment of novel antimicrobial drugs against wound infections |
| Research Themes Investment Scheme Development Funding, University of South Australia | Donner E (CI), Short M (CI), Williams C (CI), Ogunniyi AD (CI), Djordjevic S (PI) Reynolds B (PI), King B (PI) | $82,788 | 2018-2020 | Antimicrobial resistance burden in migratory and resident bird species in the northern Adelaide coastal zone |
| Partnership Enabling Grant Scheme, Division of Information Technology Engineering and the Environment, University of South Australia | Lombi E (CI), Wedding B (CI), Smith E (CI), Myers B (CI), Condina M (CI), Ogunniyi AD (CI) | $36,000 | 2018 | Use of hydrodynamic cavitation for degradation of PFAS, pathogens and antibiotic resistance genes in contaminated waters |
| ORG121561: AMPC Research Grant; Australian Meat Processor Corporation | Trott D (CI); Deo P (co-CI); Khazandi M (co-CI); Ogunniyi A (co-CI) | $30,000 | 2016 | Twin Oxide Cabinet Microbiological assessment |
| FND000138: DIIS - Innovation Connections; Australian Government Department of Industry, Innovation & Science | Trott D (CI); Ogunniyi A (co-CI); Khazandi M (co-CI) | $100,000 | 2015-2016 | Investigation of ECAS4 technology for improving water quality and shelf life in the seafood industry |
| ARC Linkage grant | JC Paton (CI), AD Ogunniyi (CI), M Alsharifi (PI), TR. Hirst (PI) | $275,000 | 2012-2015 | A single vaccine for influenza and pneumonia |
| Channel 7 Children’s Research Foundation Project Grant | AD Ogunniyi (CI), LK Mahdi (AI) | $70,000 | 2012-2013 | Molecular analysis of alpha-glycerophosphate oxidase: Role in pneumococcal meningitis |
| NHMRC Project Grant | JC Paton, AD Ogunniyi | $1,106,169 | 2010-2015 | Molecular analysis of pneumococcal pathogenesis |
| Meningitis Research Foundation (UK) | AD Ogunniyi, JC Paton, LK Mahdi |
UK£196,773 ($437,000) |
2008-2011 | Characterization and vaccine potential of pneumococcal virulence factors expressed during meningitis |
| Channel 7 Research Foundation grant | UH Stroeher (CI), AD Ogunniyi (AI) | $47,000 | 2008 | Characterisation of Virulence Genes of Streptococcus pneumoniae Involved in Otitis Media |
| NHMRC Equipment Grant | JC Paton, R Morona, AW Paton, AD Ogunniyi, AR Jilbert, SR McColl | $61,000 | 2008 | Grant to purchase small equipment |
| Women’s and Children’s Hospital Research Foundation | AD Ogunniyi, JC Paton | $40,000 | 2000 | Regulation of capsule expression in Streptococcus pneumoniae |
| Women’s and Children’s Hospital Research Foundation | JC Paton, AD Ogunniyi | $30,000 | 1999 | Regulation of capsule expression in Streptococcus pneumoniae |
Although I am a Research-only academic, I gave 2 lectures each to 2nd year Biomed, 3rd year Infection and Immunity A and MSc Biotech students annually from 2011 until the end of 2014 at The University of Adelaide. I was also involved in setting and marking exam questions for 3rd year Infection and Immunity A and MSc Biotech courses and was occasionally involved in tutorials for the MSc Biotech students during that period. I have also given a total of 13 lectures to 3rd year Infection and Immunity students at The University of South Australia (4 lectures in 2017, and 3 lectures each in 2018, 2019 and 2020). Collectively, these activities have allowed me to interact closely with all academic staff, students and colleagues, leading to exchange of ideas and problem solving as well as gaining familiarity with modern approaches to tertiary education and opportunity to attract and recruit prospective Honours, MSc and PhD students.
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | Integration of Experimental Approaches for Exploration and Development of Novel Antifungal Agents: Addressing Emerging Resistance Challenges | Doctor of Philosophy | Doctorate | Full Time | Miss Olivia Pei Ying Oh |
| 2025 | Principal Supervisor | Identification of pneumococcal serotype-independent antigenic regions and mobile genetic elements driving antimicrobial resistance gene mobility | Doctor of Philosophy | Doctorate | Full Time | Mr Gabriel Temitope Sunmonu |
| 2025 | Principal Supervisor | Identification of pneumococcal serotype-independent antigenic regions and mobile genetic elements driving antimicrobial resistance gene mobility | Doctor of Philosophy | Doctorate | Full Time | Mr Gabriel Temitope Sunmonu |
| 2025 | Co-Supervisor | Integration of Experimental Approaches for Exploration and Development of Novel Antifungal Agents: Addressing Emerging Resistance Challenges | Doctor of Philosophy | Doctorate | Full Time | Miss Olivia Pei Ying Oh |
| 2024 | Principal Supervisor | Preclinical evaluation of new derivatives of the anticoccidial drug robenidine as novel antibacterial agents | Doctor of Philosophy | Doctorate | Full Time | Ms Sayara Bista |
| 2024 | Co-Supervisor | Development of a novel controlled release anticancer drugs combination system using 3D printing | Doctor of Philosophy | Doctorate | Full Time | Songhita Mukhopadhyay |
| 2024 | Principal Supervisor | Preclinical evaluation of new derivatives of the anticoccidial drug robenidine as novel antibacterial agents | Doctor of Philosophy | Doctorate | Full Time | Ms Sayara Bista |
| 2022 | Co-Supervisor | New antimicrobial formulations and their efficacy for canine otitis externa and other fungal infections. | Doctor of Philosophy | Doctorate | Full Time | Bhumi Savaliya |
| 2022 | Co-Supervisor | New antimicrobial formulations and their efficacy for canine otitis externa and other fungal infections. | Doctor of Philosophy | Doctorate | Full Time | Bhumi Savaliya |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2018 - 2022 | Co-Supervisor | Pre-Clinical In Vitro and In Vivo Testing of Novel Antimicrobials for the Treatment of Bacterial Infections | Doctor of Philosophy | Doctorate | Full Time | Ms Hang Thi Nguyen |
| 2012 - 2017 | Co-Supervisor | Development of a Novel Co-vaccination Approach for Pneumococcal and Influenza Infections | Doctor of Philosophy | Doctorate | Full Time | Miss Rachelle Babb |
| 2010 - 2016 | Co-Supervisor | Characterisation of Streptococcus pneumoniae opacity phase variation | Doctor of Philosophy | Doctorate | Full Time | Miss Melissa Hui Chieh Chai |
| 2010 - 2013 | Co-Supervisor | Molecular Characterisation of the Polyhistidine Triad Proteins of Streptococcus Pneumoniae | Doctor of Philosophy | Doctorate | Full Time | Mr Charles Plumptre |
| 2006 - 2010 | Co-Supervisor | Pathogenesis of Streptococcus pneumoniae | Doctor of Philosophy | Doctorate | Full Time | Dr Lauren McAllister |
| 2003 - 2007 | Co-Supervisor | Differential Expression of Streptococcus Pneumoniae Genes during Pathogenesis | Doctor of Philosophy | Doctorate | Full Time | Ms Kim Suk Le Messurier |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2017 - ongoing | Co-Supervisor | The effect of hospital effluent on the antimicrobial resistance ecology of waste water. | University of South Australia | - | Master | - | Ms Hong Nguyen |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2023 - ongoing | Member | Innovation and research sub-committee, South Australian Antimicrobial Resistance Action Plan | South Australian Antimicrobial Resistance Action Plan (SAAMRAP) | Australia |
| 2022 - 2024 | Member | The University of Adelaide Animal Ethics Committee (Science) | The University of Adelaide | Australia |
| 2022 - ongoing | Member | Australian Society for Microbiology, South Australia Branch | Australian Society for Microbiology | Australia |
| 2021 - ongoing | Member | School of Animal and Veterinary Sciences Research Committee | The University of Adelaide | Australia |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2024 - ongoing | Member | Australasian Biospecimen Network Association | Australia |
| 2021 - ongoing | Member | Australian Society for Antimicrobials (ASA) | Australia |
| 2009 - ongoing | Member | Australian Society for Microbiology | Australia |