Abiodun Ogunniyi

Abiodun Ogunniyi

School of Animal and Veterinary Science

Faculty of Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


I have a long-standing interest in understanding the molecular mechanisms of bacterial pathogenesis, with emphasis on the characterisation of the virulence factors involved and evaluating the potential of candidate vaccine antigens.  My PhD was conducted under the joint supervision of Professor Paul Manning, Professor Ieva Kotlarski, and Associate Professor Renato Morona and entailed the functional characterisation of the SefA protein of Salmonella enterica serovar Enteritidis.

I carried out my postdoctoral work in Professor James Paton’s laboratory from March 1997 to December 2009 on the molecular analysis of pneumococcal pathogenesis, and became a Senior Research Fellow in January 2010.

I joined Prof Darren Trott’s group at the Australian Centre for Antimicrobial Resistance Ecology [ACARE]) in January 2015, where my research focuses on efficacy assessments of new broad-spectrum antimicrobials to address the rising incidence of multi-drug resistant bacterial pathogens, and efficacy evaluation of biocides (such as the pH-neutral electrolysed oxidising water) for wide application in health, agriculture and food industries.

Throughout my research career, I have contributed significantly to the design and execution of research projects, international research grant applications and development of new technologies. I have significantly harnessed my expertise and experience to supervise and mentor numerous Honours, MSc and PhD candidates, and I actively collaborate with national and international colleagues and postdoctoral fellows to achieve mutual success in our research activities.

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  • Journals

    Year Citation
    2021 Ogunniyi, A. D., Tenzin, S., Ferro, S., Venter, H., Pi, H., Amorico, T., . . . Trott, D. J. (2021). A pH-neutral electrolyzed oxidizing water significantly reduces microbial contamination of fresh spinach leaves. Food Microbiology, 93, 1-9.
    DOI Scopus1
    2021 Ogunniyi, A. D., Dandie, C. E., Brunetti, G., Drigo, B., Aleer, S., Hall, B., . . . Lombi, E. (2021). Neutral electrolyzed oxidizing water is effective for pre-harvest decontamination of fresh produce. Food Microbiology, 93, 10 pages.
    DOI Scopus1
    2021 Morshed, M. T., Nguyen, H. T., Vuong, D., Crombie, A., Lacey, E., Ogunniyi, A. D., . . . Piggott, A. M. (2021). Semisynthesis and biological evaluation of a focused library of unguinol derivatives as next-generation antibiotics. Organic and Biomolecular Chemistry, 19(5), 1022-1036.
    DOI Scopus2 WoS2 Europe PMC1
    2021 Nguyen, H. T., Venter, H., Veltman, T., Williams, R., Anne O'Donovan, L., Russell, C. C., . . . Trott, D. J. (2021). In vitro synergistic activity of NCL195 in combination with colistin against Gram-negative bacterial pathogens. International Journal of Antimicrobial Agents, 57(5), 106323-1-106323-13.
    DOI Scopus1 Europe PMC1
    2021 Nguyen, H. T., O’Donovan, L., Venter, H., Russell, C. C., McCluskey, A., Page, S. W., . . . Ogunniyi, A. D. (2021). Comparison of two transmission electron microscopy methods to visualize drug-induced alterations of gram-negative bacterial morphology. Antibiotics, 10(3), 307.
    DOI
    2021 André, G. O., Borges, M. T., Assoni, L., Ferraz, L. F. C., Sakshi, P., Adamson, P., . . . Darrieux, M. (2021). Protective role of PhtD and its amino and carboxyl fragments against pneumococcal sepsis.. Vaccine, 39(27), 3626-3632.
    DOI
    2021 Nguyen, H. T., Morshed, M. T., Vuong, D., Crombie, A., Lacey, E., Garg, S., . . . Ogunniyi, A. D. (2021). Evaluation of Benzguinols as Next-Generation Antibiotics for the Treatment of Multidrug-Resistant Bacterial Infections. Antibiotics, 10(6), 1-17.
    DOI
    2021 Pi, H., Ogunniyi, A. D., Savaliya, B., Nguyen, H. T., Page, S. W., Lacey, E., . . . Trott, D. J. (2021). Repurposing of the fasciolicide triclabendazole to treat infections caused by staphylococcus spp. And vancomycin-resistant enterococci. Microorganisms, 9(8), 20 pages.
    DOI
    2020 Chai, W. C., Whittall, J. J., Song, D., Polyak, S. W., Ogunniyi, A. D., Wang, Y., . . . Venter, H. (2020). Antimicrobial action and reversal of resistance in MRSA by difluorobenzamide derivatives targeted at FtsZ. Antibiotics (Basel), 9(12), 1-22.
    DOI Scopus2 WoS2
    2020 Dandie, C. E., Ogunniyi, A. D., Ferro, S., Hall, B., Drigo, B., Chow, C. W. K., . . . Lombi, E. (2020). Disinfection options for irrigation water: Reducing the risk of fresh produce contamination with human pathogens. CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 50(20), 2144-2174.
    DOI Scopus7 WoS9
    2020 Tenzin, S., Ogunniyi, A. D., Ferro, S., Deo, P., & Trott, D. J. (2020). Effects of an Eco-Friendly Sanitizing Wash on Spinach Leaf Bacterial Community Structure and Diversity. APPLIED SCIENCES-BASEL, 10(8), 15 pages.
    DOI Scopus2 WoS1
    2020 Pi, H., Nguyen, H. T., Venter, H., Boileau, A. R., Woolford, L., Garg, S., . . . Ogunniyi, A. D. (2020). In vitro activity of robenidine Analog NCL195 in combination with outer membrane permeabilizers against gram-negative bacterial pathogens and impact on systemic gram-positive bacterial infection in mice. Front Microbiol, 11, 1556.
    DOI WoS5 Europe PMC4
    2019 Oliver, E., Pope, C., Clarke, E., Langton Hewer, C., Ogunniyi, A., Paton, J., . . . Finn, A. (2019). Th17 responses to pneumococcus in blood and adenoidal cells in children. Clinical and Experimental Immunology, 195(2), 213-225.
    DOI Scopus2 WoS2 Europe PMC2
    2019 Khazandi, M., Pi, H., Chan, W. Y., Ogunniyi, A. D., Sim, J. X. F., Venter, H., . . . Trott, D. J. (2019). In vitro antimicrobial activity of robenidine, ethylenediaminetetraacetic acid and polymyxin B nonapeptide against important human and veterinary pathogens. Frontiers in Microbiology, 10(APR), 837-1-837-15.
    DOI Scopus8 WoS9 Europe PMC6
    2019 Imani Rad, H., Peeri, H., Amani, M., Mohammadnia, A., Ogunniyi, A., Khazandi, M., . . . Arzanlou, M. (2019). Allicin prevents the formation of Proteus-induced urinary crystals and the blockage of catheter in a bladder model in vitro. Microbial Pathogenesis, 132, 293-301.
    DOI WoS1
    2019 Russell, C. C., Stevens, A., Young, K. A., Baker, J. R., McCluskey, S. N., Khazandi, M., . . . McCluskey, A. (2019). Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-Amine with antibiotic activity. ChemistryOpen, 8(7), 896-907.
    DOI Scopus3 WoS3 Europe PMC1
    2019 Tenzin, S., Ogunniyi, A. D., Khazandi, M., Ferro, S., Bartsch, J., Crabb, S., . . . Trott, D. J. (2019). Decontamination of aerosolised bacteria from a pig farm environment using a pH neutral electrochemically activated solution (Ecas4 anolyte).. PloS one, 14(9), 1-5.
    DOI Scopus4 WoS4 Europe PMC3
    2019 Ogunniyi, A. D., Dandie, C. E., Ferro, S., Hall, B., Drigo, B., Brunetti, G., . . . Lombi, E. (2019). Comparative antibacterial activities of neutral electrolyzed oxidizing water and other chlorine-based sanitizers. Scientific Reports, 9(1), 19955-1-19955-13.
    DOI Scopus5 WoS4 Europe PMC1
    2018 Khazandi, M., Al-Farha, A., Coombs, G., O'Dea, M., Pang, S., Trott, D., . . . Petrovski, K. (2018). Genomic characterization of coagulase-negative staphylococci including methicillin-resistant Staphylococcus sciuri causing bovine mastitis. Veterinary Microbiology, 219, 17-22.
    DOI Scopus13 WoS12 Europe PMC2
    2018 Ogunniyi, A., Kopecki, Z., Hickey, E., Khazandi, M., Peel, E., Belov, K., . . . Trott, D. (2018). Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing. PLoS ONE, 13(7), e0200195-1-e0200195-13.
    DOI Scopus12 WoS14 Europe PMC7
    2018 Hickey, E., Wong, H., Khazandi, M., Ogunniyi, A., Petrovski, K., Garg, S., . . . Trott, D. (2018). Repurposing Ionophores as novel antimicrobial agents for the treatment of bovine mastitis caused by Gram-positive pathogens. Journal of Veterinary Pharmacology and Therapeutics, 41(5), 746-754.
    DOI Scopus11 WoS11 Europe PMC4
    2018 Russell, C. C., Stevens, A., Pi, H., Khazandi, M., Ogunniyi, A., Young, K. A., . . . McCluskey, A. (2018). Gram-positive and gram-negative antibiotic activity of asymmetric and monomeric robenidine analogues. ChemMedChem, 13(23), 2573-2580.
    DOI Scopus4 WoS4 Europe PMC2
    2017 Mahdi, L., Higgins, M., Day, C., Tiralongo, J., Hartley-Tassell, L., Jennings, M., . . . Ogunniyi, A. (2017). The pneumococcal alpha-glycerophosphate oxidase enhances nasopharyngeal colonization through binding to host glycoconjugates. EBioMedicine, 18, 236-243.
    DOI Scopus3 WoS2 Europe PMC1
    2017 Chai, M., Weiland, F., Harvey, R., Hoffmann, P., Ogunniyi, A., & Paton, J. (2017). Proteomic comparisons of opaque and transparent variants of Streptococcus pneumoniae by two dimensional-differential gel electrophoresis. Scientific Reports, 7(1), 2453-1-2453-11.
    DOI Scopus3 WoS3 Europe PMC1
    2017 Khazandi, M., Deo, P., Ferro, S., Venter, H., Pi, H., Crabb, S., . . . Trott, D. (2017). Efficacy evaluation of a new water sanitizer for increasing the shelf life of Southern Australian King George Whiting and Tasmanian Atlantic Salmon fillets. Food Microbiology, 68, 51-60.
    DOI Scopus16 WoS13 Europe PMC2
    2017 Kopecki, Z., Ogunniyi, A., Trott, D., & Cowin, A. (2017). Fighting chronic wound infection – one model at a time. Wound Practice and Research, 25(1), 6-13.
    2017 Ogunniyi, A., Khazandi, M., Stevens, A., Sims, S., Page, S., Garg, S., . . . Trott, D. (2017). Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent. PLoS ONE, 12(9), e0183457-1-e0183457-23.
    DOI Scopus22 WoS23 Europe PMC13
    2017 Babb, R., Chen, A., Ogunniyi, A., Hirst, T., Kara, E., McColl, S., . . . Paton, J. (2017). Enhanced protective responses to a serotype-independent pneumococcal vaccine when combined with an inactivated influenza vaccine. Clinical Science, 131(2), 169-180.
    DOI Scopus11 WoS12 Europe PMC6
    2017 Wang, Y., Mowla, R., Guo, L., Ogunniyi, A., Rahman, T., De Barros Lopes, M., . . . Venter, H. (2017). Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. Bioorganic and Medicinal Chemistry Letters, 27(4), 733-739.
    DOI Scopus18 WoS16 Europe PMC3
    2016 Abraham, R., Stevens, A., Young, K., Russell, C., Qvist, A., Khazandi, M., . . . Trott, D. (2016). Robenidine analogues as Gram-positive antibacterial agents. Journal of Medicinal Chemistry, 59(5), 2126-2138.
    DOI Scopus13 WoS14 Europe PMC11
    2016 Babb, R., Chen, A., Hirst, T., Kara, E., McColl, S., Ogunniyi, A., . . . Alsharifi, M. (2016). Intranasal vaccination with γ -irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses. Clinical Science, 130(9), 697-710.
    DOI Scopus32 WoS30 Europe PMC22
    2015 Iwajomo, O., Moons, P., Nkhata, R., Mzinza, D., Ogunniyi, A., Williams, N., . . . Finn, A. (2015). Delayed reconstitution of B cell immunity to pneumococcus in HIV-infected Malawian children on antiretroviral therapy. Journal of Infection, 70(6), 616-623.
    DOI Scopus6 WoS5 Europe PMC5
    2015 Le, N. T., Jeong, H. Y., Kwon, H. Y., Ogunniyi, A. D., Paton, J. C., Pyo, S. N., & Rhee, D. K. (2015). Erratum to Modulation of adherence, invasion, and tumor necrosis factor alpha secretion during the early stages of infection by Streptococcus pneumoniae ClpL [Infection and Immunity, 75, 6 (2007) 2996-3005, 2007]. Infection and Immunity, 83(3), 1224.
    DOI Scopus1 WoS1 Europe PMC1
    2015 Fruzangohar, M., Ebrahimie, E., Ogunniyi, A. D., Mahdi, L. K., Paton, J. C., & Adelson, D. L. (2015). Correction: Comparative GO: A web application for comparative gene ontology and gene ontology-based gene selection in bacteria. PLoS ONE, 10(4), 1 page.
    DOI Scopus4 WoS3 Europe PMC2
    2015 Knippenberg, S., Ueberberg, B., Maus, R., Bohling, J., Ding, N., Tort Tarres, M., . . . Maus, U. (2015). Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin. Thorax, 70(7), 636-646.
    DOI Scopus53 WoS54 Europe PMC31
    2015 Kara, E., McKenzie, D., Bastow, C., Gregor, C., Fenix, K., Ogunniyi, A., . . . McColl, S. (2015). CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nature Communications, 6(1), 8644-1-8644-1 7.
    DOI Scopus71 WoS72 Europe PMC52
    2015 Mahdi, L., Van der Hoek, M., Ebrahimie, E., Paton, J., & Ogunniyi, A. (2015). Characterization of pneumococcal genes involved in bloodstream invasion in a mouse model. PLoS One, 10(11), e0141816-1-e0141816-15.
    DOI Scopus13 WoS13 Europe PMC13
    2014 Mahdi, L., Deihimi, T., Zamansani, F., Fruzangohar, M., Adelson, D., Paton, J., . . . Ebrahimie, E. (2014). A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease. BMC Genomics, 15(1), 769-1-769-15.
    DOI Scopus16 WoS14 Europe PMC14
    2014 Plumptre, C., Eijkelkamp, B., Morey, J., Behr, F., Couñago, R., Ogunniyi, A., . . . McDevitt, C. (2014). AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology, 91(4), 834-851.
    DOI Scopus69 WoS67 Europe PMC55
    2014 Manso, A., Chai, M., Atack, J., Furi, L., Croix, M., Haigh, R., . . . Oggioni, M. (2014). A random six-phase switch regulates pneumococcal virulence via global epigenetic changes. Nature Communications, 5(1), 5055-1-5055-9.
    DOI Scopus128 WoS127 Europe PMC106
    2013 Plumptre, C., Ogunniyi, A., & Paton, J. (2013). Vaccination against Streptococcus pneumoniae using truncated derivatives of polyhistidine triad protein D. PLoS One, 8(10), 1-11.
    DOI Scopus21 WoS20 Europe PMC16
    2013 Iwajomo, O., Finn, A., Ogunniyi, A., Williams, N., & Heyderman, R. (2013). Impairment of pneumococcal antigen specific isotype-switched IgG memory B-cell immunity in HIV infected Malawian adults. PLoS One, 8(11), 1-7.
    DOI Scopus9 WoS9 Europe PMC7
    2013 Plumptre, C., Ogunniyi, A., & Paton, J. (2013). Surface association of Pht proteins of Streptococcus pneumoniae. Infection and Immunity, 81(10), 3644-3651.
    DOI Scopus23 WoS21 Europe PMC15
    2013 Mahdi, L., Ebrahimie, E., Adelson, D., Paton, J., & Ogunniyi, A. (2013). A transcription factor contributes to pathogenesis and virulence in streptococcus pneumoniae. PLoS One, 8(8), 1-9.
    DOI Scopus13 WoS12 Europe PMC11
    2013 Fruzangohar, M., Ebrahimie, E., Ogunniyi, A., Mahdi, L., Paton, J., & Adelson, D. (2013). Comparative GO: a web application for comparative Gene Ontology and Gene Ontology-based gene selection in bacteria. PLoS One, 8(3), 1-8.
    DOI Scopus43 WoS41 Europe PMC30
    2013 Basavanna, S., Chimalapati, S., Maqbool, A., Rubbo, B., Yuste, J., Wilson, R., . . . Brown, J. (2013). The effects of methionine acquisition and synthesis on Streptococcus pneumoniae growth and virulence. PLoS One, 8(1), 1-14.
    DOI Scopus37 WoS37 Europe PMC30
    2012 Brumshagen, C., Maus, R., Bischof, A., Ueberberg, B., Bohling, J., Osterholzer, J., . . . Maus, U. (2012). FMS-like tyrosine kinase 3 ligand treatment of mice aggravates acute lung injury in response to Streptococcus pneumoniae: Role of pneumolysin. Infection and Immunity, 80(12), 4281-4290.
    DOI Scopus16 WoS16 Europe PMC13
    2012 Plumptre, C., Ogunniyi, A., & Paton, J. (2012). Polyhistidine triad proteins of pathogenic streptococci. Trends in Microbiology, 20(10), 485-493.
    DOI Scopus38 WoS38 Europe PMC34
    2012 Ogunniyi, A., Mahdi, L., Trappetti, C., Verhoeven, N., Mermans, D., Van der Hoek, M., . . . Paton, J. (2012). Identification of genes that contribute to the pathogenesis of invasive Pneumococcal Disease by in vivo transcriptomic analysis. Infection and Immunity, 80(9), 3268-3278.
    DOI Scopus45 WoS41 Europe PMC34
    2012 Mahdi, L., Wang, H., Van der Hoek, M., Paton, J., & Ogunniyi, A. (2012). Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice. Journal of Clinical Investigation, 122(6), 2208-2220.
    DOI Scopus40 WoS37 Europe PMC31
    2012 Weber, M., Lambeck, S., Ding, N., Henken, S., Kohl, M., Deigner, H., . . . Bauer, M. (2012). Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia. FASEB Journal, 26(6), 2424-2436.
    DOI Scopus28 WoS29 Europe PMC19
    2012 McAllister, L., Ogunniyi, A., Stroeher, U., & Paton, J. (2012). Contribution of a genomic accessory region encoding a putative cellobiose phosphotransferase system to virulence of Streptococcus Pneumoniae. PLoS One, 7(2), 1-9.
    DOI Scopus18 WoS18 Europe PMC13
    2011 McAllister, L., Ogunniyi, A., Stroeher, U., Leach, A., & Paton, J. (2011). Contribution of serotype and genetic background to virulence of serotype 3 and serogroup 11 pneumococcal isolates. Infection and Immunity, 79(12), 4839-4849.
    DOI Scopus21 WoS19 Europe PMC15
    2011 McDevitt, C., Ogunniyi, A., Valkov, E., Lawrence, M., Kobe, B., McEwan, A., & Paton, J. (2011). A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7(11), 2357-2365.
    DOI Scopus238 WoS231 Europe PMC164
    2011 Harvey, R., Ogunniyi, A., Chen, A., & Paton, J. (2011). Pneumolysin with low hemolytic activity confers an early growth advantage to Streptococcus pneumoniae in the blood. Infection and Immunity, 79(10), 4122-4130.
    DOI Scopus39 WoS36 Europe PMC28
    2011 Iwajomo, O., Finn, A., Moons, P., Nkhata, R., Sepako, E., Ogunniyi, A., . . . Heyderman, R. (2011). Deteriorating pneumococcal-specific B-cell memory in minimally symptomatic African children with HIV infection. The Journal of Infectious Diseases, 204(4), 534-543.
    DOI Scopus26 WoS25 Europe PMC24
    2011 van Bueren, A., Ficko-Blean, E., Pluvinage, B., Hehemann, J., Higgins, M., Deng, L., . . . Boraston, A. (2011). The conformation and function of a multimodular glycogen-degrading pneumococcal virulence factor. Structure, 19(5), 640-651.
    DOI Scopus37 WoS35 Europe PMC20
    2011 Trappetti, C., Ogunniyi, A., Oggioni, M., & Paton, J. (2011). Extracellular matrix formation enhances the ability of streptococcus pneumoniae to cause invasive disease. PLoS One, 6(5), 1-17.
    DOI Scopus49 WoS44 Europe PMC39
    2011 Harvey, R., Stroeher, U., Ogunniyi, A., Smith-Vaughan, H., Leach, A., & Paton, J. (2011). A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence. PLoS One, 6(5), 1-14.
    DOI Scopus36 WoS32 Europe PMC30
    2011 Ota, M., Oluwalana, C., Howie, S., Gomez, M., Ogunniyi, A., Mendy-Gomez, A., . . . Adegbola, R. (2011). Antibody and T-cell responses during acute and convalescent stages of invasive pneumococcal disease. International Journal of Infectious Diseases, 15(4), E282-E288.
    DOI Scopus2 WoS2 Europe PMC2
    2011 Paton, J. C., & Ogunniyi, A. D. (2011). Evicting the pneumococcus from its nasopharyngeal lodgings. Cell Host and Microbe, 9(2), 89-91.
    DOI Scopus2 WoS2 Europe PMC1
    2010 Ogunniyi, A., Mahdi, L., Jennings, M., McEwan, A., McDevitt, C., Van der Hoek, M., . . . Paton, J. (2010). Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae. Journal of Bacteriology, 192(17), 4489-4497.
    DOI Scopus69 WoS65 Europe PMC53
    2010 Henken, S., Bohling, J., Ogunniyi, A., Paton, J., Salisbury, V., Welte, T., & Maus, U. (2010). Evaluation of biophotonic imaging to estimate bacterial burden in mice infected with highly virulent compared to less virulent Streptococcus pneumoniae serotypes. Antimicrobial Agents and Chemotherapy, 54(8), 3155-3160.
    DOI Scopus17 WoS17 Europe PMC14
    2010 Henken, S., Bohling, J., Martens-Lobenhoffer, J., Paton, J., Ogunniyi, A., Briles, D., . . . Maus, U. (2010). Efficacy profiles of Daptomycin for treatment of Iinvasive and noninvasive pulmonary infections with treptococcus pneumoniae. Antimicrobial Agents and Chemotherapy, 54(2), 707-717.
    DOI Scopus27 WoS27 Europe PMC22
    2009 Ogunniyi, A., Grabowicz, M., Mahdi, L., Cook, J., Gordon, D., Sadlon, T., & Paton, J. (2009). Pneumococcal histidine triad proteins are regulated by the Zn²⁺-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H. FASEB Journal, 2008(3), 1-8.
    DOI Scopus95 WoS88 Europe PMC72
    2008 Ogunniyi, A., Paton, J., Kirby, A., McCullers, J., Cook, J., Hyodo, M., . . . Karaolis, D. (2008). C-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection. Vaccine, 26(36), 4676-4685.
    DOI Scopus63 WoS53 Europe PMC42
    2008 Mahdi, L., Ogunniyi, A., Le Messurier, K., & Paton, J. (2008). Pneumococcal Virulence Gene Expression and Host Cytokine Profiles during Pathogenesis of Invasive Disease. Infection and Immunity, 76(2), 646-657.
    DOI Scopus49 WoS47 Europe PMC43
    2007 Tu, L., Jeong, H., Kwon, H., Ogunniyi, A., Paton, J., Pyo, S., & Rhee, D. (2007). Modulation of adherence invasion and tumor necrosis factor alpha secretion during the early stages of infection by Strepococcus pneumoniae ClpL. Infection and Immunity, 75(6), 2996-3005.
    DOI Scopus24 WoS18 Europe PMC21
    2007 Ogunniyi, A., Le Messurier, K., Graham, R., Watt, J., Briles, D., Stroeher, U., & Paton, J. (2007). Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model. Infection and Immunity, 75(4), 1843-1851.
    DOI Scopus73 WoS71 Europe PMC56
    2007 Ogunniyi, A., Grabowicz, M., Briles, D., Cook, J., & Paton, J. (2007). Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infection and Immunity, 75(1), 350-357.
    DOI Scopus150 WoS142 Europe PMC120
    2006 Le Messurier, K., Ogunniyi, A., & Paton, J. (2006). Differential expression of key pneumococcal virulence genes in vivo. Microbiology, 152(2), 305-311.
    DOI Scopus90 WoS81 Europe PMC69
    2004 Kwon, H., Ogunniyi, A., Choi, M., Pyo, S., Rhee, D., & Paton, J. (2004). The ClpP protease of Streptococcus pneumoniae modulates virulence gene expression and protects against fatal pneumococcal challenge. Infection and Immunity, 72(10), 5646-5653.
    DOI Scopus78 WoS78 Europe PMC61
    2004 McAllister, L., Tseng, H., Ogunniyi, A., Jennings, M., McEwan, A., & Paton, J. (2004). Molecular analysis of the psa permease complex of Streptococcus pneumoniae. Molecular Microbiology, 53(3), 889-901.
    DOI Scopus104 WoS104 Europe PMC88
    2004 Brown, J. S., Ogunniyi, A. D., Woodrow, M. C., Holden, D. W., & Paton, J. C. (2004). Erratum: Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection (Infection and Immunity (2001) 69, 11 (6702-6706)). Infection and Immunity, 72(11), 6755.
    DOI Scopus1 WoS1
    2003 Chapuy-Regaud, S., Ogunniyi, A., Diallo, N., Huet, Y., Desnottes, J., Paton, J., . . . Trombe, M. (2003). RegR, a global LacI/GalR family regulator, modulates virulence and competence in Streptococcus pneumoniae. Infection and Immunity, 71(5), 2615-2625.
    DOI Scopus34 WoS32 Europe PMC26
    2003 Stroeher, U., Paton, A., Ogunniyi, A., & Paton, J. (2003). Mutation of luxS of Streptococcus pneumoniae affects virulence in a mouse model. Infection and Immunity, 71(6), 3206-3212.
    DOI Scopus77 WoS72 Europe PMC55
    2003 Kwon, H., Kim, S., Choi, M., Ogunniyi, A., Paton, J., Park, S., . . . Rhee, D. (2003). Effect of heat shock and mutations in ClpL and ClpP on virulence gene expression in Streptococcus pneumoniae. Infection and Immunity, 71(7), 3757-3765.
    DOI Scopus84 WoS85 Europe PMC66
    2002 Duthy, T., Ormsby, R., Giannakis, E., Ogunniyi, A., Stroeher, U., Paton, J., & Gordon, D. (2002). The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15. Infection and Immunity, 70(10), 5604-5611.
    DOI Scopus67 WoS65 Europe PMC48
    2002 Ogunniyi, A., Giammarinaro, P., & Paton, J. (2002). The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo. Microbiology, 148(Part 7), 2045-2053.
    DOI Scopus112 WoS104 Europe PMC76
    2002 Ogunniyi, A., Kotlarski, I., Morona, R., & Manning, P. (2002). Epitope analysis of the FanC subunit protein of the K99 (F5) fimbriae of enterotoxigenic Escherichia coli using a recombinant fusion technique. FEMS Immunology and Medical Microbiology, 34(1), 23-31.
    DOI Scopus6 WoS5 Europe PMC4
    2001 Ogunniyi, A., Woodrow, M., Poolman, J., & Paton, J. (2001). Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA. Infection and Immunity, 69(10), 5997-6003.
    DOI Scopus120 WoS108 Europe PMC90
    2001 Brown, J., Ogunniyi, A., Woodrow, M., Holden, D., & Paton, J. (2001). Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection. Infection and Immunity, 69(11), 6702-6706.
    DOI Scopus133 WoS126 Europe PMC102
    2000 Ogunniyi, A., Folland, R., Briles, D., Hollingshead, S., & Paton, J. (2000). Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae. Infection and Immunity, 68(5), 3028-3033.
    DOI Scopus167 WoS161 Europe PMC128
    1999 Berry, A., Ogunniyi, A., Miller, D., & Paton, J. (1999). Comparative virulence of Streptococcus pneumoniae strains with insertion-duplication, point, and deletion mutations in the pneumolysin gene. Infection and Immunity, 67(2), 981-985.
    DOI Scopus73 WoS71 Europe PMC53
    1999 Auzat, I., Chapuy-Regaud, S., Bras, G., Santos, D., Ogunniyi, A., Thomas, I., . . . Trombe, M. (1999). The NADH oxidase of Streptococcus pneumoniae: Its involvement in competence and virulence. Molecular Microbiology, 34(5), 1018-1028.
    DOI Scopus101 WoS97 Europe PMC79
    1999 Palmen, R., Ogunniyi, A., Berroy, P., Larpin, S., Paton, J., & Trombe, M. (1999). Insertional mutation of orfD of the DCW cluster of Streptococcus pneumoniae attenuates virulence. Microbial Pathogenesis, 27(6), 337-348.
    DOI Scopus5 WoS5 Europe PMC3
    1998 Pilling, P. A., Lawrence, M. C., Berry, A. M., Ogunniyi, A. D., Lock, R. A., & Paton, J. C. (1998). Expression, purification and preliminary X-ray crystallographic analysis of PsaA, a putative metal-transporter protein of Streptococcus pneumoniae. Acta Crystallographica Section D: Biological Crystallography, 54(6 PART II), 1464-1466.
    DOI Scopus30 WoS29 Europe PMC19
    1998 Lawrence, M. C., Pilling, P. A., Epa, V. C., Berry, A. M., Ogunniyi, A. D., & Paton, J. C. (1998). The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein. Structure, 6(12), 1553-1561.
    DOI Scopus172 WoS172 Europe PMC111
    1997 Ogunniyi, A., Kotlarski, I., Morona, R., & Manning, P. (1997). Role of SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar enteritidis. Infection and Immunity, 65(2), 708-717.
    DOI Scopus41 WoS37 Europe PMC21
    1997 Ogunniyi, A., Kotlarski, I., Morona, R., & Manning, P. (1997). Role of the SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis. Infection and Immunity, 65(February), 708-717.
    1996 Lamikanra, A., Ako-Nai, A. K., & Ogunniyi, D. A. (1996). Transferable antibiotic resistance in Escherichia coli isolated from healthy Nigerian school children. International Journal of Antimicrobial Agents, 7(1), 59-64.
    DOI Scopus10
    1994 Ogunniyi, A. D., Manning, P. A., & Kotlarski, I. (1994). A Salmonella enteritidis 11RX pilin induces strong T-lymphocyte responses. Infection and Immunity, 62(12), 5376-5383.
    DOI Scopus33 Europe PMC19
    1994 Ogunniyi, A. D., Manning, P. A., & Kotlarski, I. (1994). A Salmonella enteritidis 11RX pilin induces strong T-lymphocyte responses. Infection and Immunity, 62(12), 5376-5383.
    DOI Scopus33 Europe PMC19
    1991 Ako-Nai, A. K., Torimiro, S. E. A., Lamikanra, A., & Ogunniyi, A. D. (1991). A survey of nasal carriage of Staphylococcus aureus in a neonatal ward in Ile-Ife, Nigeria. Annals of Tropical Paediatrics, 11(1), 41-45.
    DOI Scopus12 Europe PMC4
    1991 Ako-Nai, A. K., Ogunniyi, A. D., Lamikanra, A., & Torimiro, S. E. A. (1991). The characterisation of clinical isolates of Staphylococcus aureus in Ile-Ife, Nigeria. Journal of Medical Microbiology, 34(2), 109-112.
    DOI Scopus23 Europe PMC10
  • Book Chapters

    Year Citation
    2015 Ogunniyi, A., & Paton, J. (2015). Vaccine Potential of Pneumococcal Proteins. In J. Brown, S. Hammerschmidt, & C. Orihuela (Eds.), Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions (pp. 59-78). United Kingdom: Elsevier.
    DOI Scopus6
    2013 Ogunniyi, A., & Paton, J. (2013). Regulation of pneumococcal surface proteins and capsule. In M. Vasil, & A. Darwin (Eds.), Regulation of Bacterial Virulence (1 ed., pp. 190-208). United States: American Society for Microbiology Press.
    DOI
  • Conference Papers

    Year Citation
    2015 Knippenberg, S., Ueberberg, B., Maus, R., Bohling, J., Ding, N., Tarres, M. T., . . . Maus, U. (2015). Streptococcus Pneumoniae Triggers Progression Of Pulmonary Fibrosis Through Pneumolysin. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 191 (pp. 1 page). Denver, CO: AMER THORACIC SOC.
  • Conference Items

    Year Citation
    2017 Pi, H., Khazandi, M., Ogunniyi, A. D., Page, S. W., Venter, H., & Trott, D. J. (2017). Characterization of a potential newclass of antimicrobial agent for Gram-negative bacteria. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. Taipei, TAIWAN: ELSEVIER SCIENCE BV.
    2016 Kopecki, Z., Ogunniyi, A. D., Trott, D., & Cowin, A. J. (2016). DEVELOPMENT OF NOVEL BIOLUMINESCENT MODELS OF WOUND INFECTION. Poster session presented at the meeting of WOUND REPAIR AND REGENERATION. WILEY-BLACKWELL.
    2011 Weber, M., Lambeck, S., Ding, N., Henken, S., Kohl, M., Deigner, H., . . . Bauer, M. (2011). Hepatic Induction of Cholesterol Biosynthesis Reflects a Remote Adaptive Response to Pneumococcal Pneumonia. Poster session presented at the meeting of INFECTION. SPRINGER HEIDELBERG.
  • Report for External Bodies

    Year Citation
    2007 Steinhoff, M. C. (2007). Animal models for protein pneumococcal vaccine evaluation: A summary. Elsevier BV.
    DOI
  • Patents

    Year Citation
    2016 Alsharifi, M., Babb, R., Chen, A. Y., David, S. C., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). 050231, Streptococcal Vaccine. Australia.
    2016 Alsharifi, M., Babb, R., Chen, A. Y., David, S. C., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2016). 050231, Streptococcal Vaccine. Australia.
    2015 Alsharifi, M., Babb, R., Chen, A. Y., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2015). 2015901098, Streptococcal Vaccine. Australia.
    2015 Alsharifi, M., Babb, R., Chen, A. Y., Hirst, T. R., Ogunniyi, A. D., & Paton, J. C. (2015). 2015901098, Streptococcal Vaccine. Australia.
    2005 Rhee, D., Kwon, H., Choi, M., Ogunniyi, A., & Paton, J. (2005). WO/2005/063283, Vaccine comprising recombinant CIpP protein of streptococcus Pneumoniae. Korea.

Funding Scheme

CI/PI/AI Names

Amount Funded

Years of Funding

Project Title

NHMRC Project Grant 627142

Paton JC (CI), Ogunniyi AD (CI)

$1,048,125

2010-2015

Molecular analysis of pneumococcal pathogenesis

ARC Linkage grant LP120200244

Paton JC (CI), Ogunniyi AD (CI), Alsharifi M (PI), Hirst TR (PI)

$275,000

2012-2015

A single vaccine for influenza and pneumonia

Meningitis Research Foundation (UK) Grant 0802.0

Ogunniyi AD (CI), Paton JC (CI), Mahdi LK (CI)

UK£196,773 ($437,000)

2008-2011

Characterization and vaccine potential of pneumococcal virulence factors expressed during meningitis

0001039884: Australian Government Department of Industry, Innovation & Science (DIIS) - Innovation Connections (Managed by RBP)

Trott D (CI); Ogunniyi A (AI); Khazandi M (AI)

$199,668

2015-2016

Investigation of ECAS4 technology for improving water quality and shelf life in the seafood industry

Contract Research (A158095); Contracting Party: Virbac Australia Pty Ltd

Trott D (CI); Ogunniyi A (CI)

$64,730

2015-2016

Comparative minimum inhibitory concentration (MIC) testing

ORG121561: AMPC Research Grant; Australian Meat Processor Corporation

Trott D (CI); Deo P (CI); Khazandi M (CI); Ogunniyi A (CI)

$30,000

2016

Twin Oxide Cabinet Microbiological assessment

Channel 7 Children’s Research Foundation Project Grant 75109360

Ogunniyi AD (CI), Mahdi LK (AI)

$70,000

2012-2013

Molecular analysis of alpha-glycerophosphate oxidase: Role in pneumococcal meningitis

NHMRC Equipment Grant

Paton JC, Morona R, Paton AW, Ogunniyi AD, Jilbert AR, McColl SR

$61,000

2008

Facility for in vivo transcriptional analysis of the host-pathogen interaction

Channel 7 Children’s Research Foundation Project Grant

Stroeher UH (CI), Ogunniyi AD (AI)

$47,000

2008

Characterisation of virulence genes of Streptococcus pneumoniae involved in otitis media

Partnership Enabling Grant Scheme, Division of Information Technology Engineering and the Environment, University of South Australia

Lombi E (CI), Wedding B (CI), Smith E (CI), Myers B (CI), Condina M (CI), Ogunniyi AD (CI)

$36,000

2018

Use of hydrodynamic cavitation for degradation of PFAS, pathogens and antibiotic resistance genes in contaminated waters

Research Themes Investment Scheme Development Funding, University of South Australia

Donner E (CI), Short M (CI), Williams C (CI), Ogunniyi AD (CI), Djordjevic S (PI) Reynolds B (PI), King B (PI)

$82,788

2018-2020

Antimicrobial resistance burden in migratory and resident bird species in the northern Adelaide coastal zone

Research Themes Investment Scheme, University of South Australia

Kopecki Z (CI), Cowin A (CI), Venter H (CI), Garg, S (CI), Coad B (CI) Page, S (PI), Trott D (CI), Ogunniyi AD (PI)

$40,000

2016

New in vivo technologies for preclinical assessment of novel antimicrobial drugs against wound infections

Contract Research (UA183243-S01); Contracting Party: Bayer Australia Ltd

Trott D (CI); Ogunniyi A (CI)

$47,911

2018

Mastitis Product Registration (benzyl penicillin) MIC Study

Research Themes Investment Scheme (101796) Seed Funding, University of South Australia

Thomas N (CI), Prestidge C (CI), Ogunniyi AD (CI), Kopecki Z (CI), Cowin A (CI), Wormald PJ (PI)

$40,000

2018

Re-sensitising resistant bacteria against antibiotics: Giving new power to failing medicines

DEBRA Australia

Kopecki Z (CI), Cowin A (CI), Vasilev K (CI), Ogunniyi AD (CI)

$40,000

2018

Safe and intelligent dressings for treatment of infected wounds

Contract Research (UA172408); Contracting Party: CSIRO

Trott D (CI); Ogunniyi A (CI)

$33,150

2018

Literature Review on the presence of antimicrobial resistance (AMR) in food in Australia and New Zealand

Contract Research (UA194233); Contracting Party: Botanix Pharmaceuticals Ltd

Ogunniyi AD

$19,546

2019

Efficacy testing of synthetic cannabidiol in a bioluminescent murine model of Staphylococcus aureus scald wound infection

Contract Research Variation 1 (UA194233-S02); Contracting Party: Botanix Pharmaceuticals Ltd

Ogunniyi AD

$42,594

2019

Efficacy testing of synthetic cannabidiol in a bioluminescent murine model of Staphylococcus aureus scald wound infection

 

Although I am a Research-only academic, I gave 2 lectures each to 2nd year Biomed, 3rd year Infection and Immunity A and MSc Biotech students annually from 2011 until the end of 2014 at The University of Adelaide. I was also involved in setting and marking exam questions for 3rd year Infection and Immunity A and MSc Biotech courses and was occasionally involved in tutorials for the MSc Biotech students during that period. I have also given a total of 13 lectures to 3rd year Infection and Immunity students at The University of South Australia (4 lectures in 2017, and 3 lectures each in 2018, 2019 and 2020). Collectively, these activities have allowed me to interact closely with all academic staff, students and colleagues, leading to exchange of ideas and problem solving as well as gaining familiarity with modern approaches to tertiary education and opportunity to attract and recruit prospective Honours, MSc and PhD students.

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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2018 Co-Supervisor Development of Bioluminescent Mouse Models for Pre-clinical Testing of Novel Antimicrobials for Treatment of Gram-negative Bacterial Infections Doctor of Philosophy Doctorate Full Time Ms Hang Thi Nguyen
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2012 - 2017 Co-Supervisor Development of a Novel Co-vaccination Approach for Pneumococcal and Influenza Infections Doctor of Philosophy Doctorate Full Time Miss Rachelle Babb
    2010 - 2016 Co-Supervisor Characterisation of Streptococcus pneumoniae opacity phase variation Doctor of Philosophy Doctorate Full Time Miss Melissa Hui Chieh Chai
    2010 - 2013 Co-Supervisor Molecular Characterisation of the Polyhistidine Triad Proteins of Streptococcus Pneumoniae Doctor of Philosophy Doctorate Full Time Mr Charles Plumptre
    2006 - 2010 Co-Supervisor Pathogenesis of Streptococcus pneumoniae Doctor of Philosophy Doctorate Full Time Dr Lauren McAllister
    2003 - 2007 Co-Supervisor Differential Expression of Streptococcus Pneumoniae Genes during Pathogenesis Doctor of Philosophy Doctorate Full Time Ms Kim Suk Le Messurier
  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2017 - ongoing Co-Supervisor The effect of hospital effluent on the antimicrobial resistance ecology of waste water. University of South Australia Master Ms Hong Nguyen
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  • Memberships

    Date Role Membership Country
    2009 - ongoing Member Australian Society for Microbiology Australia

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