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Professor David Adelson

David Adelson
Chair of Bioinformatics & Computational Genet
School of Biological Sciences
Faculty of Sciences

David Adelson is Professor and Chair of Bioinformatics and Computational Genetics, Zhendong Chair of Molecular Traditional Chinese Medicine in the School of Biological Sciences at the University of Adelaide and is also a Xinglin Scholar Professor at Guangzhou University of TCM. Prof. Adelson’s current research also focuses on the non-coding portions of animal genomes, such as regions used to transcribe ncRNAs (piRNAs and lncRNAs) and the computational analysis of repetitive, so called “Junk DNA”, in order to understand large scale evolutionary/structural changes in animal genomes. Prof. Adelson has led the analysis of repetitive DNA for the cow, horse and elephant genome sequencing consortia and his lab is currently working on the Tuatara repetitive DNA analysis for that international genome sequencing consortium. In addition to characterising repeat content in genomes, his lab has also developed a set of tools to identify and annotate transposable elements and segmental duplications “from scratch”. Additional aspects of the genome evolution work include understanding the impact of horizontal transfer of repetitive elements in higher organisms.

Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.

Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.

Prior to moving to Adelaide in 2007, Prof Adelson worked at Texas A&M University from 2001, and before that worked for CSIRO from 1988. Prof Adelson obtained his PhD in Biomedical Sciences (Biochemistry), from the John A Burns School of Medicine at the University of Hawaii at Manoa in 1985 and carried out postdoctoral research at Duke University.

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Professor David Adelson

David Adelson is Professor and Chair of Bioinformatics and Computational Genetics, Zhendong Chair of Molecular Traditional Chinese Medicine in the School of Biological Sciences at the University of Adelaide and is also a Xinglin Scholar Professor at Guangzhou University of TCM. Prof. Adelson’s current research also focuses on the non-coding portions of animal genomes, such as regions used to transcribe ncRNAs (piRNAs and lncRNAs) and the computational analysis of repetitive, so called “Junk DNA”, in order to understand large scale evolutionary/structural changes in animal genomes. Prof. Adelson has led the analysis of repetitive DNA for the cow, horse and elephant genome sequencing consortia and his lab is currently working on the Tuatara repetitive DNA analysis for that international genome sequencing consortium. In addition to characterising repeat content in genomes, his lab has also developed a set of tools to identify and annotate transposable elements and segmental duplications “from scratch”. Additional aspects of the genome evolution work include understanding the impact of horizontal transfer of repetitive elements in higher organisms.

Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.

Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.

Prior to moving to Adelaide in 2007, Prof Adelson worked at Texas A&M University from 2001, and before that worked for CSIRO from 1988. Prof Adelson obtained his PhD in Biomedical Sciences (Biochemistry), from the John A Burns School of Medicine at the University of Hawaii at Manoa in 1985 and carried out postdoctoral research at Duke University.

Eligible to supervise Masters and PhD — email supervisor to discuss availability.

My research has two main themes: 1)understanding how transposable elements affect genome structure and function at both the individual and species level and 2)using systems biology and network based methods to understand the molecular mode of action of complex mixtures of bioactives such as Traditional Chinese Medicines. 

Journals

Year Citation
2018 Zeng, L., Pederson, S., Kortschak, D., & Adelson, D. (2018). Transposable elements and gene expression during the evolution of amniotes.
DOI
2018 Stringer, J., Forster, S., Qu, Z., Prokopuk, L., O'Bryan, M., Gardner, D., . . . Western, P. (2018). Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance. BMC Biology, 16(1), 104.
DOI
2018 Alanazi, I., Ebrahimie, E., Hoffmann, P., & Adelson, D. (2018). Correction to: Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis (Apoptosis, (2013), 18, 11, (1291-1305), 10.1007/s10495-013-0887-6). Apoptosis, 23(1), 92.
DOI
2018 Palkopoulou, E., Lipson, M., Mallick, S., Nielsen, S., Rohland, N., Baleka, S., . . . Reich, D. (2018). A comprehensive genomic history of extinct and living elephants. Proceedings of the National Academy of Sciences of the United States of America, 115(11), 2566-2574.
DOI Scopus3 Europe PMC2
2018 Zeng, L., Kortschak, R., Raison, J., Bertozzi, T., & Adelson, D. (2018). Superior ab initio identification, annotation and characterisation of TEs and segmental duplications from genome assemblies. PLoS ONE, 13(3), 1-17.
DOI Scopus1 WoS1 Europe PMC1
2018 Buckley, R., Kortschak, R., & Adelson, D. (2018). Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse.. PLoS computational biology, 14(4), e1006091.
DOI
2018 Zeng, L., Pederson, S., Cao, D., Qu, Z., Hu, Z., Adelson, D., & Wei, C. (2018). Genome-Wide Analysis of the Association of Transposable Elements with Gene Regulation Suggests that Alu Elements Have the Largest Overall Regulatory Impact. Journal of Computational Biology, 25(6), 1-12.
DOI
2018 Hin, N., Newman, M., Kaslin, J., Douek, A., Lumsden, A., Zhou, X., . . . Lardelli, M. (2018). Accelerated brain aging towards transcriptional inversion in a zebrafish model of familial Alzheimer's disease. BioRxiv, OnlinePubl.
DOI
2018 Mills, P., Adelson, D., & Yu, I. (2018). Chinese herbal medicine versus other interventions in the treatment of type 2 diabetes: A systematic review of randomized controlled trial.. Journal of Evidence-Based Medicine, 23, 1-10.
DOI
2018 Zeng, L., Pederson, S., Kortschak, R., & Adelson, D. (2018). Transposable elements and gene expression during the evolution of amniotes. Mobile DNA, 9(1), 1-9.
DOI
2018 Ivancevic, A., Kortschak, R., Bertozzi, T., & Adelson, D. (2018). Horizontal transfer of BovB and L1 retrotransposons in eukaryotes. Genome Biology, 19(1), 13 pages.
DOI
2018 Liang, Q., Qu, Z., Liang, Y., Feng, Q., Niu, X., Bai, T., . . . Adelson, D. (2018). Zuo gui wan alters expression of energy metabolism genes and prevents cell death in high-glucose loaded mouse embryos. Evidence-based Complementary and Alternative Medicine, 2018, 11 pages.
DOI
2018 Aung, T. (2018). Cell Cycle, Energy Metabolism and DNA Repair Pathways in Cancer Cells are Suppressed by Compound Kushen Injection.. BioRxiv.
DOI
2018 Banjar, H., Adelson, D., Brown, F., & Chaudhri, N. (2018). Corrigendum: Intelligent techniques using molecular data analysis in leukaemia: An opportunity for personalized medicine support system (BioMed Research International (2017) 2017 (12) DOI: 10.1155/2017/3587309). BioMed Research International, 2018, 1 page.
DOI
2017 Ivancevic, A., Kortschak, D., Bertozzi, T., & Adelson, D. (2017). Re-evaluating inheritance in genome evolution: widespread transfer of LINEs between species.
DOI
2017 Aung, T., Qu, Z., Kortschak, R., & Adelson, D. (2017). Understanding the effectiveness of natural compound mixtures in cancer through their molecular mode of action. International Journal of Molecular Sciences, 18(3), 20 pages.
DOI Scopus14 WoS11 Europe PMC6
2017 Daniel Kortschak, R., & L Adelson, D. (2017). bíogo/ncbi: interfaces to NCBI services for the Go language. The Journal of Open Source Software, 2(13), 234.
DOI
2017 Yu, C., Qu, Z., Zhang, Y., Zhang, X., Lan, T., Adelson, D., . . . Zhu, Y. (2017). Seed weight differences between wild and domesticated soybeans are associated with specific changes in gene expression. Plant Cell Reports, 36(9), 1417-1426.
DOI
2017 Hempfling, A., Lim, S., Adelson, D., Evans, J., O Connor, A., Qu, Z., . . . Bergmann, M. (2017). Expression patterns of HENMT1 and PIWIL1 in human testis: implications for transposon expression. Reproduction, 154(4), 363-374.
DOI Scopus2 WoS2 Europe PMC2
2017 Li, J., Harata-Lee, Y., Denton, M., Feng, Q., Rathjen, J., Qu, Z., & Adelson, D. (2017). Long read reference genome-free reconstruction of a full-length transcriptome from Astragalus membranaceus reveals transcript variants involved in bioactive compound biosynthesis. Cell Discovery, 3, 17031-1-17031-13.
DOI Scopus3 WoS2 Europe PMC3
2017 Buckley, R., Kortschak, R., Raison, J., & Adelson, D. (2017). Similar evolutionary trajectories for retrotransposon accumulation in mammals. Genome Biology and Evolution, 9(9), 2336-2353.
DOI Scopus4 WoS4 Europe PMC4
2017 Banjar, H., Adelson, D., Brown, F., & Leclercq, T. (2017). Personalized medicine support system : resolving conflict in allocation to risk groups and predicting patient molecular response to targeted therapy. Health Informatics - An International Journal, 6(2), 1-21.
DOI
2017 Banjar, H., Adelson, D., Brown, A., & Chaudhri, N. (2017). Intelligent techniques using molecular data analysis in leukaemia: an opportunity for personalized medicine support system. BioMed Research International, 2017, 3587309-1-3587309-21.
DOI WoS1 Europe PMC1
2017 Banjar, H., Ranasinghe, D., Brown, F., Adelson, D., Kroger, T., Leclercq, T., . . . Chaudhri, N. (2017). Modelling predictors of molecular response to frontline imatinib for patients with chronic myeloid leukaemia. PLoS ONE, 12(1), 1-23.
DOI Scopus2 WoS1
2017 Wang, D., Qu, Z., Yang, L., Zhang, Q., Liu, Z., Do, T., . . . Zhu, J. (2017). Transposable elements (TEs) contribute to stress-related long intergenic noncoding RNAs in plants. Plant Journal, 90(1), 133-146.
DOI Scopus17 WoS15 Europe PMC8
2017 Fruzangohar, M., Ebrahimie, E., & Adelson, D. (2017). A novel hypothesis-unbiased method for gene ontology enrichment based on transcriptome data. PLoS ONE, 12(2), e0170486-1-e0170486-14.
DOI Scopus3 WoS3 Europe PMC3
2017 Kortschak, R., Pedersen, B., & Adelson, D. (2017). bíogo/hts: high throughput sequence handling for the Go language. The Journal of Open Source Software, 2(10), 168-1.
DOI
2017 Kortschak, R., Snyder, J., Maragkakis, M., & Adelson, D. (2017). bíogo: a simple high-performance bioinformatics toolkit for the Go language. The Journal of Open Source Software, 2(10), 1.
DOI
2016 Ling, K., Brautigan, P., Moore, S., Fraser, R., Leong, M., Leong, J., . . . Scott, H. (2016). In depth analysis of the Sox4 gene locus that consists of sense and natural antisense transcripts. Data in Brief, 7, 282-290.
DOI Scopus2 Europe PMC2
2016 Qu, Z., Cui, J., Harata-Lee, Y., Thazin Nwe Aung, T., Feng, Q., Raison, J., . . . Adelson, D. (2016). Identification of candidate anti-cancer molecular mechanisms of compound kushen injection using functional genomics. Oncotarget, 7(40), 66003-66019.
DOI Scopus14 WoS15 Europe PMC5
2016 Ivancevic, A., Kortschak, R., Bertozzi, T., & Adelson, D. (2016). LINEs between species: evolutionary dynamics of LINE-1 retrotransposons across the eukaryotic tree of life. Genome Biology and Evolution, 8(11), 3301-3322.
DOI Scopus14 WoS12 Europe PMC12
2016 Ling, K., Brautigan, P., Moore, S., Fraser, R., Cheah, P., Raison, J., . . . Scott, H. (2016). Derivation of an endogenous small RNA from double-stranded Sox4 sense and natural antisense transcripts in the mouse brain. Genomics, 107(2-3), 88-99.
DOI Scopus8 WoS7 Europe PMC8
2015 Fruzangohar, M., Ebrahimie, E., Ogunniyi, A., Mahdi, L., Paton, J., & Adelson, D. (2015). Correction: Comparative GO: A web application for comparative gene ontology and gene ontology-based gene selection in bacteria. PLoS ONE, 10(4), 1 page.
DOI Scopus3 WoS2 Europe PMC2
2015 McMichael, G., Bainbridge, M., Haan, E., Corbett, M., Gardner, A., Thompson, S., . . . MacLennan, A. (2015). Whole-exome sequencing points to considerable genetic heterogeneity of cerebral palsy. Molecular Psychiatry, 20(2), 176-182.
DOI Scopus39 WoS33 Europe PMC31
2015 Alanazi, I., Hoffmann, P., & Adelson, D. (2015). MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells. PLoS One, 10(3), e0120337-1-e0120337-20.
DOI Scopus10 WoS11 Europe PMC11
2015 Hu, Z., Scott, H., Qin, G., Zheng, G., Chu, X., Xie, L., . . . Wei, C. (2015). Revealing missing human protein isoforms based on ab initio prediction, RNA-seq and proteomics. Scientific Reports, 5(1), 10940-1-10940-15.
DOI Scopus8 WoS7 Europe PMC6
2015 Lim, S., Qu, Z., Kortschak, R., Lawrence, D., Geoghegan, J., Hempfling, A., . . . O'Bryan, M. (2015). HENMT1 and piRNA stability are required for adult male germ cell transposon repression and to define the spermatogenic program in the mouse. PLoS Genetics, 11(10), e1005620-1-e1005620-30.
DOI Scopus26 WoS23 Europe PMC21
2015 Lim, S. L., Qu, Z. P., Kortschak, R. D., Lawrence, D. M., Geoghegan, J., Hempfling, A. -L., . . . O'Bryan, M. K. (2015). Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.. PLoS genetics, 11(12), e1005782.
DOI Europe PMC1
2014 Mahdi, L., Deihimi, T., Zamansani, F., Fruzangohar, M., Adelson, D., Paton, J., . . . Ebrahimie, E. (2014). A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease. BMC Genomics, 15(1), 769-1-769-15.
DOI Scopus9 WoS9 Europe PMC10
2014 Ghosh, S., Qu, Z., Das, P., Fang, E., Juras, R., Cothran, E., . . . Raudsepp, T. (2014). Copy number variation in the horse genome. PLoS Genetics, 10(10), e1004712-1-e1004712-19.
DOI Scopus23 WoS22 Europe PMC22
2014 Jiang, Y., Xie, M., Chen, W., Talbot, R., Maddox, J., Faraut, T., . . . Dalrymple, B. (2014). The sheep genome illuminates biology of the rumen and lipid metabolism. Science, 344(6188), 1168-1173.
DOI Scopus136 WoS126 Europe PMC112
2014 Buckley, R., & Adelson, D. (2014). Mammalian genome evolution as a result of epigenetic regulation of transposable elements. Biomolecular Concepts, 5(3), 183-194.
DOI Scopus3 Europe PMC2
2014 Gagliardi, L., Schreiber, A., Hahn, C., Feng, J., Cranston, T., Boon, H., . . . Scott, H. (2014). ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism, 99(9), E1784-E1792.
DOI Scopus44 WoS39 Europe PMC29
2014 Ebrahimi, M., Aghagolzadeh, P., Shamabadi, N., Tahmasebi, A., Alsharifi, M., Adelson, D., . . . Ebrahimie, E. (2014). Understanding the undelaying mechanism of HASubtyping in the level of physic-chemal characteristics of protein. PLoS One, 9(5), e96984-1-e96984-14.
DOI Scopus10 WoS10 Europe PMC5
2014 Lim, S., Kortschak, R., & Adelson, D. (2014). Discovery of a novel long terminal repeat (LTR2i-SS) in Sus Scrofa. Animal Genetics, 45(3), 367-372.
DOI
2014 Wang, D., Qu, Z., Adelson, D., Zhu, J., & Timmis, J. (2014). Transcription of nuclear organellar DNA in a model plant system. Genome Biology and Evolution, 6(6), 1327-1334.
DOI Scopus8 WoS7 Europe PMC6
2013 Ivancevic, A., Walsh, A., Kortschak, R., & Adelson, D. (2013). Jumping the fine LINE between species: Horizontal transfer of transposable elements in animals catalyses genome evolution. Bioessays, 35(12), 1071-1082.
DOI Scopus30 WoS26 Europe PMC23
2013 Bellone, R., Holl, H., Sealuri, V., Devi, S., Maddodi, N., Archer, S., . . . Brooks, S. (2013). Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse. PLoS One, 8(10), 1-14.
DOI Scopus37 WoS33 Europe PMC26
2013 Alanazi, I., Ebrahimie, E., Hoffmann, P., & Adelson, D. (2013). Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis. Apoptosis, 18(11), 1291-1305.
DOI Scopus20 WoS17 Europe PMC8
2013 Fruzangohar, M., Kroeger, T., & Adelson, D. (2013). Improved part-of-speech prediction in suffix analysis. PLoS One, 8(10), 1-6.
DOI Scopus6 WoS5 Europe PMC1
2013 Mahdi, L., Ebrahimie, E., Adelson, D., Paton, J., & Ogunniyi, A. (2013). A transcription factor contributes to pathogenesis and virulence in streptococcus pneumoniae. PLoS One, 8(8), 1-9.
DOI Scopus12 WoS11 Europe PMC10
2013 Roberts, N., Kortschak, R., Parker, W., Schreiber, A., Branford, S., Scott, H., . . . Adelson, D. (2013). A comparative analysis of algorithms for somatic SNV detection in cancer. Bioinformatics, 29(18), 2223-2230.
DOI Scopus42 WoS42 Europe PMC37
2013 Fruzangohar, M., Ebrahimie, E., Ogunniyi, A., Mahdi, L., Paton, J., & Adelson, D. (2013). Comparative GO: a web application for comparative Gene Ontology and Gene Ontology-based gene selection in bacteria. PLoS One, 8(3), 1-8.
DOI Scopus29 WoS29 Europe PMC21
2013 Walsh, A., Kortschak, R., Gardner, M., Bertozzi, T., & Adelson, D. (2013). Widespread horizontal transfer of retrotransposons. Proceedings of the National Academy of Sciences of the United States of America, 110(3), 1012-1016.
DOI Scopus54 WoS49 Europe PMC45
2012 Qu, Z., & Adelson, D. (2012). Identification and comparative analysis of ncRNAs in human, mouse and zebrafish indicate a conserved role in regulation of genes expressed in brain. PLoS One, 7(12), 1-14.
DOI Scopus21 WoS16 Europe PMC17
2012 Qu, Z., & Adelson, D. (2012). Bovine ncRNAs are abundant, primarily intergenic, conserved and associated with regulatory genes. PLoS One, 7(8), 1-14.
DOI Scopus29 WoS19 Europe PMC24
2012 Qu, Z., & Adelson, D. (2012). Evolutionary conservation and functional roles of ncRNA. Frontiers in Genetics, 3(205), 1-11.
DOI Scopus19 Europe PMC15
2011 Vidale, P., Piras, F., Nergadze, S., Bertoni, L., Verini-Supplizi, A., Adelson, D., . . . Giulotto, E. (2011). Chromosomal assignment of six genes (EIF4G3, HSP90, RBBP6, IL8, TERT, and TERC) in four species of the genus Equus. Animal Biotechnology, 22(3), 119-123.
DOI Scopus1 Europe PMC1
2011 Ling, K., Brautigan, P., Hahn, C., Daish, T., Rayner, J., Cheah, P., . . . Scott, H. (2011). Deep sequencing analysis of the developing mouse brain reveals a novel microRNA. BMC Genomics, 12(1), 1-15.
DOI Scopus39 WoS33 Europe PMC30
2011 Appels, R., Adelson, D., Moolhiujzen, P., Webster, H., Barrero, R., & Bellgard, M. (2011). Genome studies at the PAG 2011 conference. Functional & Integrative Genomics, 11(1), 1-11.
DOI Scopus2 WoS2 Europe PMC4
2011 Childers, C., Reese, J., Sundaram, J., Vile, D., Dickens, C., Childs, K., . . . Elsik, C. (2011). Bovine Genome Database: Integrated tools for genome annotation and discovery. Nucleic Acids Research, 39(SUPPL. 1), D830-D834.
DOI Scopus20 WoS19 Europe PMC11
2010 Adelson, D., Raison, J., Garber, M., & Edgar, R. (2010). Interspersed repeats in the horse (Equus caballus); spatial correlations highlight conserved chromosomal domains. Animal Genetics, 41(Suppl 2), 91-99.
DOI Scopus12 WoS9 Europe PMC7
2010 Rios, J., Fleming, J., Bryant, U., Carter, C., Huber, J., Long, M., . . . Adelson, D. (2010). OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horses. PLoS One, 5(5), 1-9.
DOI Scopus26 WoS23 Europe PMC18
2009 Bovine Genome Sequencing and Analysis Consortium., Elsik, C., Tellam, R., & Worley, K. (2009). The genome sequence of Taurine cattle: a window to ruminant biology and evolution. Science, 324(5926), 522-528.
DOI Scopus673 WoS613 Europe PMC496
2009 Wade, C., Giulotto, E., Sigurdsson, S., Zoli, M., Gnerre, S., Imsland, F., . . . Guerin, G. (2009). Genome sequence, comparative analysis, and population genetics of the domestic horse. Science, 326(5954), 865-867.
DOI Scopus405 WoS373 Europe PMC305
2009 Satterfield, M., Song, G., Kochan, K., Riggs, P., Simmons, R., Elsik, C., . . . Spencer, T. (2009). Discovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation. Physiological Genomics, 39(2), 85-99.
DOI Scopus55 WoS54 Europe PMC42
2009 Adelson, D., Raison, J., & Edgar, R. (2009). Characterization and distribution of retrotransposons and simple sequence repeats in the bovine genome. Proceedings of the National Academy of Sciences of the United States of America, 106(31), 12855-12860.
DOI Scopus52 WoS48 Europe PMC37
2009 Salih, H., & Adelson, D. (2009). QTL global meta-analysis: are trait determining genes clustered?. BMC Genomics, 10(1), 1-8.
DOI Scopus18 WoS15 Europe PMC11
2008 Adelson, D. (2008). Insights and applications from sequencing the bovine genome. Reproduction Fertility and Development, 20(1), 54-60.
DOI Scopus5 WoS3 Europe PMC4
2007 Rios, J., Perelygin, A., Long, M., Lear, T., Zharkikh, A., Brinton, M., & Adelson, D. (2007). Characterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes. BMC Genomics, 8(313), WWW 1-WWW 14.
DOI Scopus10 WoS8 Europe PMC7
2007 Brooks, S., Lear, T., Adelson, D., & Bailey, E. (2007). A chromosome inversion near the KIT gene and the Tobiano spotting pattern in horses. Cytogenetic and Genome Research, 119(3-4), 225-230.
DOI Scopus48 WoS43 Europe PMC29
2007 Murphy, B., Lear, T., Adelson, D., & Fitzgerald, B. (2007). Chromosomal assignments and sequences for the equine core circadian clock genes. Animal Genetics, 38(1), 84-85.
DOI Scopus7 WoS5 Europe PMC3
2007 Snelling, W., Chiu, R., Schein, J., Hobbs, M., Abbey, C., Adelson, D., . . . Zhao, S. (2007). A physical map of the bovine genome. Genome Biology, 8(8), 1-17.
DOI Scopus57 WoS47 Europe PMC40
2007 Seabury, C., Gill, C., Templeton, J., Dyar, J., Derr, J., Adelson, D., . . . Womack, J. (2007). Molecular characterization of the Rocky Mountain elk (Cervus elaphus nelsoni) PRNP putative promoter. Journal of Heredity, 98(7), 678-686.
DOI Scopus1 Europe PMC1
2007 Lewis, S., Farmer, J., Burghardt, R., Newton, G., Johnson, G., Adelson, D., . . . Spencer, T. (2007). Galectin 15 (LGALS15): A gene uniquely expressed in the uteri of sheep and goats that functions in trophoblast attachment. Biology of Reproduction, 77(6), 1027-1036.
DOI Scopus34 WoS34 Europe PMC28
2006 Gray, C., Abbey, C., Beremand, P., Choi, Y., Farmer, J., Adelson, D., . . . Spencer, T. (2006). Identification of endometrial genes regulated by early pregnancy progesterone and interferon tau in the ovine uterus. Biology of Reproduction, 74(2), 383-394.
DOI Scopus116 WoS110 Europe PMC88
2006 Nergadze, S., Magnani, E., Attolini, C., Bertoni, L., Adelson, D., Cappelli, K., . . . Giulotto, E. (2006). Assignment of the Equus caballus interleukin 8 gene (IL8) to chromosome 3q14.2→q14.3 by in situ hybridization. Cytogenetic and Genome Research, 112(3-4), 341B.1-341B.2.
DOI Scopus4 WoS4 Europe PMC3
2006 Bellone, R., Lear, T., Adelson, D., & Bailey, E. (2006). Comparative mapping of oculocutaneous albinism type II (OCA2) transient receptor potential cation channel subfamily M member 1 (TRPM1) and two equine microsatellites ASBO8 and 1CA43 among four equid species by fluorescence in situ hybridization. Cytogenetic and Genome Research, 114(1), 93A1-93A3.
DOI Scopus9 WoS7 Europe PMC6
2006 Polineni, P., Aragonda, A., Xavier, S., Furuta, R., & Adelson, D. (2006). The bovine QTL viewer: A web accessible database of bovine Quantitative Trait Loci. BMC Bioinformatics, 7(5), 7 pages.
DOI Scopus33 WoS35 Europe PMC21
2006 Wunderlich, K., Abbey, C., Clayton, D., Song, Y., Schein, J., Georges, M., . . . Gill, C. (2006). A 2.5-Mb contig constructed from Angus Longhorn and horned Hereford DNA spanning the polled interval on bovine chromosome 1. Animal Genetics, 37(6), 592-594.
DOI Scopus12 WoS10 Europe PMC10
2005 Yilmaz, A., Shen, S., Adelson, D., Xavier, S., & Zhu, J. (2005). Identification and sequence analysis of chicken Toll-like receptors. Immunogenetics, 56(10), 743-753.
DOI Scopus112 WoS109 Europe PMC74
2005 Wang, J., Adelson, D., Yilmaz, A., Sze, S., Jin, Y., & Zhu, J. (2005). Genomic organization, annotation, and ligand-receptor inferences of chicken chemokines and chemokine receptor genes based on comparative genomics. BMC Genomics, 6, 45-1-45-17.
DOI Scopus42 WoS39 Europe PMC29
2005 Yilmaz, A., Adelson, D., Xavier, S., & Zhu, J. (2005). Annotation of the chicken IL10 gene cluster and effects of lipopolysaccharide stimulation on IL10 gene expression. Animal Genetics, 36(3), 263-265.
DOI Scopus2 WoS2 Europe PMC2
2005 Dunlap, K., Palmarini, M., Adelson, D., & Spencer, T. (2005). Sheep endogenous betaretroviruses (enJSRVs) and the hyaluronidase 2 (HYAL2) receptor in the ovine uterus and conceptus. Biology of Reproduction, 73(2), 271-279.
DOI Scopus42 WoS37 Europe PMC25
2004 Adelson, D., Cam, G., DeSilva, U., & Franklin, I. (2004). Gene expression in sheep skin and wool (hair). Genomics, 83(1), 95-105.
DOI Scopus18 WoS16 Europe PMC11
2004 Lee, E., Raudsepp, T., Kata, S., Adelson, D., Womack, J., Skow, L., & Chowdhary, B. (2004). A 1.4-Mb interval RH map of horse chromosome 17 provides detailed comparison with human and mouse homologues. Genomics, 83(2), 203-215.
DOI Scopus18 WoS15 Europe PMC12
2004 Gray, C., Adelson, D., Bazer, F., Burghardt, R., Meeusen, E., & Spencer, T. (2004). Discovery and characterization of an epithelial-specific galectin in the endometrium that forms crystals in the trophectoderm. Proceedings of the National Academy of Sciences of the United States of America, 101(21), 7982-7987.
DOI Scopus102 WoS94 Europe PMC70
2004 Ward, T., Valberg, S., Adelson, D., Abbey, C., Binns, M., & Mickelson, J. (2004). Glycogen branching enzyme (GBE1) mutation causing equine glycogen storage disease IV. Mammalian Genome, 15(7), 570-577.
DOI Scopus53 WoS38 Europe PMC23
2003 Hamernik, D., & Adelson, D. (2003). USDA stakeholder workshop on animal bioinformatics: Summary and recommendations. Comparative and Functional Genomics, 4(2), 271-274.
DOI Scopus1 WoS1
2003 DeSilva, U., Franklin, I., Maddox, J., van Hest, B., & Adelson, D. (2003). Systematic screening of sheep skin cDNA libraries for microsatellite sequences. Cytogenetic and Genome Research, 102(1-4), 79-84.
DOI Scopus4 WoS3 Europe PMC2
2002 Adelson, D., Hollis, D., & Brown, G. (2002). Wool fibre diameter and follicle density are not specified simultaneously during wool follicle initiation. Australian Journal of Agricultural Research, 53(9), 1003-1009.
DOI Scopus9 WoS10
2001 Maddox, J., Davies, K., Crawford, A., Hulme, D., Vaiman, D., Cribiu, E., . . . van Hest, B. (2001). An enhanced linkage map of the sheep genome comprising more than 1000 loci. Genome Research, 11(7), 1275-1289.
DOI Scopus200 WoS188 Europe PMC127
1998 Wessel, G., Berg, L., Adelson, D., Cannon, G., & McClay, D. (1998). A molecular analysis of hyalin - A substrate for cell adhesion in the hyaline layer of the sea urchin embryo. Developmental Biology, 193(2), 115-126.
DOI Scopus59 WoS56 Europe PMC41
1997 Adelson, D., Hollis, D., Merchant, J., & Kelley, B. (1997). In vivo effects of epidermal growth factor on epidermal pattern formation and hair follicle initiation in the marsupial bandicoot Isoodon macrourus. Reproduction, Fertility and Development, 9(5), 493-500.
DOI Scopus6 WoS5 Europe PMC6
1992 Adelson, D., Alliegro, M., & McClay, D. (1992). On the ultrastructure of hyalin, a cell adhesion protein of the sea urchin embryo extracellular matrix. Journal of Cell Biology, 116(5), 1283-1289.
DOI Scopus19 WoS19 Europe PMC9
1992 Adelson, D., Kelley, B., & Nagorcka, B. (1992). Increase in dermal papilla cells by proliferation during development of the primary wool follicle. Australian Journal of Agricultural Research, 43(4), 843-856.
DOI Scopus15
1992 Campbell, M., Dollin, A., & Adelson, D. (1992). Differential lectin binding to presumptive cortical cells of the wool follicle bulb. Journal of Cell Science, 102(2), 353-360.
Scopus6 WoS6 Europe PMC5
1988 Adelson, D., & Humphreys, T. (1988). Sea urchin morphogenesis and cell-hyalin adhesion are perturbed by a monoclonal antibody specific for hyalin. Development, 104(3), 391-402.
Scopus66 WoS67 Europe PMC39
1985 Noll, H., Matranga, V., Cervello, M., Humphreys, T., Kuwasaki, B., & Adelson, D. (1985). Characterization of toposomes from sea urchin blastula cells: A cell organelle mediating cell adhesion and expressing positional information. Proceedings of the National Academy of Sciences of the United States of America, 82(23), 8062-8066.
DOI Scopus46 WoS56 Europe PMC21

Book Chapters

Year Citation
2015 Adelson, D. L., Qu, Z., Raison, J. M., & Lim, S. L. (2015). Bovine Genomics. In D. J. Garrick, & A. Ruvinsky (Eds.), The Genetics of Cattle (2nd Edition ed., pp. 130-152). Wallingford, Oxfordshire, UK: CAB International.
2012 Adelson, D. (2012). Bovine genome architecture. In J. E. Womack (Ed.), Bovine Genomics (1 ed., pp. 123-140). United Kingdom: Wiley.
DOI

Conference Papers

Year Citation
2015 Adelson, D., Buckley, R., Ivancevic, A., Qu, Z., & Zeng, L. (2015). Retrotransposons: Genomic and trans-genomic agents of change. In Unknown Conference (pp. 55-75).
DOI Scopus1
2014 Ling, K., Lee, H., Brautigan, P., Moore, S., Fraser, R., Cheah, P., . . . Scott, H. (2014). Deciphering the secret role of Sox4 gene locus during mouse cerebral corticogenesis. In Journal of Neurochemistry Vol. 130 (pp. 8). Kaohsiung, Taiwan: Wiley.

Conference Items

Year Citation
2017 Nourmohammadi, S., Pie, V. J., Kourghi, M., De leso, M. L., Pak, C., Adelson, D. L., & Yool, A. J. (2017). (Oral presentation) Analysis of effective compounds and mechanisms of action of a Chinese traditional herbal medicine (Compound Kushen Injection) on aquaporins involved in cancer cell migration and metastasis.. Poster session presented at the meeting of Gage Ion Channels and Transporters Conference. Canberra, Australia.
2012 Ghosh, S., Das, P., Qu, Z., Fang, E., Arnold, C., Adelson, D., . . . Raudsepp, T. (2012). Array CGH Studies in Equine Disorders of Sexual Development - SRY-Positive Sex Reversal and Cryptorchidism. Poster session presented at the meeting of CYTOGENETIC AND GENOME RESEARCH. San Antonio, TX: KARGER.

Internet Publications

Year Citation
2017 Zeng, L., Pederson, S. M., Cao, D., Qu, Z., Adelson, D., & Wei, C. (2017). Genome-Wide Analysis Of Repetitive Elements Associated With Gene Regulation. biorXiv.
DOI

Research Support: (Ongoing Research support)

 

NHMRC Project Grant 1123341                          Scott (CIA)                       2017-2019

Genetic autopsy of perinatal death: diagnosis and discovery by Genome Sequencing 

Role: Co-CI (CIF)                                                                                        A$989,332

 

NHMRC Project Grant 1144966                          Western(CIA)                   2018-2020

Defining the epigenetic origins of maternally inherited disease.                     A$731,162

Role: Co-CI (CID)

 

NHMRC Project Grant 1144887                          Western(CIA)                   2018-2020

Determining the impacts of epigenetic modifying drugs on germline programming and offspring health

Role: Co-CI (CIC)                                                                                       A$863,918

 

Completed Project Funding (since 2001).

 

USDA-CSREES NRI                                           Chowdhary (PI)                2003-2006

High resolution integrated genetic and physical map of the equine genome. US$870,892

Role: Co-I

 

Kleberg Foundation Gift                                     Womack (PI)                    2005-2007

Bovine Genomics Bioinformatics                                                                 US$1,000,000

Role: Co-PI

 

Texas Equine Research Fund                             Adelson (PI)                     2005-2007

Bioinformatics Support for Equine Genomics                                               US$26,000

 

NSF                                                                    Young(PI)                       2005-2008

Phages of Agronomic Bacteria: A Student Based Genomics Approach.        US$261,329

Role: Co-PI

 

USDA CSREES NRI                                            Elsik (PI)                         2007-2010

Bovine Genome Database: A Community Informatics Resource                  US$999,595

Role: Co-PI

 

ARC LIEF Grant                                                  Leinweber (CI)                2011

Enhancement of South Australian high-performance computing facilities       A$430,000

Role: CI

 

ANDS Project                                                      Adelson(CI)                     2011-2012

Genomics Data Capture                                                                             A$250,000

Role: Sole CI

 

ARC Linkage Project                                           Cooper(CI)                      2009-2011

Environmental Genomics: Mining, climate change, water, crime and health   A$500,000

Role: CI

 

USDA AFRI                                                        Elsik (PI)                          2010-2013

Next Generation Bovine Genome Database                                                US$970,000

Role: Co-PI

 

NHMRC Project Grant 1011334                          Scott (CIA)                       2011-2013

Dnmt3L haploinsufficent retrotransposition leads to genetic hypermutation    A$593,390

Role: CI

 

NHMRC Project Grant                                        Scott (CIA)                       2012-2014

Identification of genes responsible for familial predispositions to haematological malignancies

Role: CI                                                                                                     A$689,754

 

NHMRC Project Grant                                        Branford (CIA)                   2012-2014

Assessment of markers of genomic instability for the prediction of treatment response in chronic myeloid leukaemia.                                                                                   A$570,093

Role: CI

 

NHMRC Project Grant                                        MacLennan (CIA)              2012-2014

Copy number variations in cerebral palsy                                                     A$639,877

Role: CI

 

NHMRC Project Grant                                        Jensen (CIA)                     2012-2014

Understanding the post- transcriptional regulatory roles of the Hu family of RNA-binding proteins using HITS-CLIP

Role: CI                                                                                                     A$568,660

 

ARC Discovery Project                                        O’Bryan (CIA)                   2012-2014

HEN1 is a regulator of piRNA metabolism, transcriptional regulation and mammalian male fertility

Role: CI                                                                                                     A$344,000

 

Zhendong Pharmaceutical Co Ltd                       Adelson(CI)                      2012-2017

Zhendong Centre                                                                                      A$2,250,000

Role: CI/Director

 

The Australian Cancer Research Foundation       Lopez(CI)                         2010-2017

The ACRF Cancer Genome Facility

Role: Co-CI

A$3,500,000 (ACRF), A$1,050,000 (SA Dept of Health), A$500,000 (Cancer Council SA), A$250,000 (DIISR SuperScience Project, Australian National Data Service), A$400,000 (RAH research funds), A$1,500,000 (5 salaries for 3 years, Medvet PTY LTD (2), SA Pathology RIBG (1), Adelaide University (1 RIBG, 1 IGS) = CI with 11 others.(Lopez, Kumar, Hughes, Scott, Goodall, Tilley, McColl, Paton, Adelson, Gécz, Melo, To)

 

 

 

I teach into second and third year genetics and second year biomedical science.  At postgraduate level, I teach into the Masters of Bioinformatics program.

Current Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2018 Co-Supervisor Understanding of the Molecular Mechanisms of Aquaporins in Human Cancer Doctor of Philosophy Doctorate Full Time Mr Saeed Nourmohammadi
2018 Principal Supervisor Structural variation in complex genomes Doctor of Philosophy Doctorate Full Time Dr Mani Ghani Poor Samami
2018 Co-Supervisor Transcriptome analysis of genetic zebrafish models of familial Alzheimer's disease and human sporadic Alzheimer's disease Doctor of Philosophy Doctorate Full Time Miss Nhi Hin
2017 Co-Supervisor The Role of M5C on mRNA and lncRNA Master of Philosophy Master Full Time Miss Pei Qin Ng
2017 Principal Supervisor Evolutionary Impact of Transposable Elements on Higher Organisms Doctor of Philosophy Doctorate Full Time Mr James Douglas Galbraith
2017 Principal Supervisor Statistical modelling and analysis of genome wide changes in chromatin structure as determined by ChIP seq Master of Philosophy Master Full Time Miss Catisha Leigh Coburn
2016 Co-Supervisor The role of RNA modifications in plants Doctor of Philosophy Doctorate Full Time Miss Jun Li
2016 Co-Supervisor Functional analysis of the regulating factors controlling gene expression in cattle Doctor of Philosophy Doctorate Full Time Ms Cynthia Liu
2015 Principal Supervisor Molecular Mode of Action of Traditional Chinese Medicine Doctor of Philosophy Doctorate Full Time Mrs Thazin Nwe Aung
2015 Principal Supervisor The systems biology approach to reveal the molecular basis of TCM Doctor of Philosophy Doctorate Full Time Mr Hanyuan Shen

Past Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2015 - 2018 Principal Supervisor Personalized Medicine Support System for Chronic Myeloid Leukaemia Patients Doctor of Philosophy Doctorate Full Time Mrs Haneen Reda M Banjar
2014 - 2018 Principal Supervisor The Impact of Transposable Elements on Amniote Evolution Doctor of Philosophy Doctorate Full Time Miss Lu Zeng
2014 - 2018 Principal Supervisor Research on Compound Kushen Injection (CKI): Anti-cancer Mechanism Pathway/Network structure Doctor of Philosophy Doctorate Full Time Mr Jian Cui
2014 - 2017 Principal Supervisor Jumping the Fine LINE Between Species: Horizontal Transfer and Evolution of Repetitive Elements in Eukaryotic Species Doctor of Philosophy Doctorate Full Time Dr Atma Maria Ivancevic
2013 - 2017 Principal Supervisor Evolution of mammalian genome architecture through retrotransposition Doctor of Philosophy Doctorate Full Time Reuben Mackenzie Buckley
2012 - 2014 Principal Supervisor Functional analysis of repeat regions in the eukaryotic genomes Master of Philosophy under a Jointly-awarded Degree Agreement with Master Full Time Miss Lu Zeng
2011 - 2015 Co-Supervisor Investigation and Application of Methods for Ancient DNA Research Doctor of Philosophy Doctorate Full Time Dr Steve Richards
2010 - 2014 Principal Supervisor Biomedical Literature Mining Doctor of Philosophy Doctorate Full Time Mr Mario Fruzangohar
2010 - 2014 Principal Supervisor Identification and Annotation of Recombinant Repeats In Mammals Indicates They Are Experimental Products For Creating Novel Transposable Element Families Doctor of Philosophy Doctorate Full Time Mr Sim Lin Lim
2009 - 2015 Co-Supervisor Investigating the evolution of replication timing and monoallelic expression in mammals and birds Doctor of Philosophy Doctorate Full Time Miss Megan Wright
2009 - 2013 Co-Supervisor Imprinted Gene Expression and Phenotype of Bovine Concepti with Bos taurus and Bos indicus Genetics Doctor of Philosophy Doctorate Full Time Dr Mani Ghani Poor Samami
2009 - 2013 Co-Supervisor Chloroplast DNAs Diversify Nuclear and Mitochondrial Genomes in Plants Doctor of Philosophy Doctorate Full Time Mr Dong Wang
2008 - 2013 Principal Supervisor Comprehensive Identification and Annotation of Non-Protein-Coding Transcriptomes from Vertebrates Indicates Most ncRNAs are Regulatory Doctor of Philosophy Doctorate Full Time Dr Zhipeng Qu
2008 - 2014 Principal Supervisor "Understanding the Apoptotic Signaling Pathway that Involve In Breast Cancer Using Microarray, Proteomics and Bioinformatics Doctor of Philosophy Doctorate Full Time Mr Ibrahim Oqla Alanazi

Committee Memberships

Date Role Committee Institution Country
2017 - ongoing Member ABACBS Conference Committee Australia
Position
Chair of Bioinformatics & Computational Genet
Phone
83137555
Fax
8313 4362
Campus
North Terrace
Building
The Braggs, floor 2
Room Number
261
Org Unit
Molecular and Biomedical Science

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