Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Catharine Jawahar is a lecturer at the Discipline of Psychiatry, University of Adelaide. She coordinates the undergraduate, Fundamentals of Biological Psychiatry course. Her research focus is on understanding the mechanisms mediating psychosocial stress effects to increased risk of psychiatric disorders.
Broadly, my research is on understanding the effects of psychosocial stress on brain development, neuroendocrine and immune functions and behaviors across life-span. As a molecular biologist with a specific interest in the genetics of psychiatric disorders, my research aims to unravel the complex interplay of genes and environment in the onset and progression of various psychiatric disorders. In particular, my research focus is on the effect of early life stressors and their role in programming the brain for later-life psychopathology in either adolescence or adulthood. My primary expertise is with animal models of psychiatric endophenotypes, focused on the effect of early stress and trauma in WT or genetically modified mouse strains. More recently I have also been working with clinical cohorts of depression and psychosis within the discipline in collaboration with other researchers.
Title: DNA methylation effects of childhood trauma exposure in adult psychopathology
Description: This study will analyze epigenome-wide and candidate based methylation differences between those exposed to high vs low childhood trauma. The study will use a small pilot data from a larger Cognitive and Functional analysis in Mood study (CoFaMS) and conduct a systematic review of existing research to understand if distinct methylation profiles underlie various childhood stressor effects.
Project available for Third-year students
Research project start: Semester 1 and 2
Date Position Institution name 2016 - ongoing Lecturer The University of Adelaide 2011 - 2016 Research Officer/Postgraduate Coordinator University of Adelaide
Language Competency Hindi Can read, write, speak and understand spoken Tamil Can read, write, speak, understand spoken and peer review
Date Institution name Country Title 2005 - 2010 University of Melbourne Australia PhD 1999 - 2004 Bharathidasan University India MSc, Life Sciences
Year Citation 2019 Jawahar, M., Toben, C., & Baune, B. (2019). Gene-environment interactions and epigenetic mechanisms in depression. In J. L. de Quevedo, A. F. Carvalho, & C. A. Zarate (Eds.), Neurobiology of Depression: Road to Novel Therapeutics (pp. 17-25). Londone, United Kingdom: Academic Press.
2018 Jawahar, M., & Baune, B. T. (2018). Biological Embedding of Childhood Maltreatment in Adult Depression. In B. T. Baune (Ed.), Inflammation and Immunity in Depression Basic Science and Clinical Applications (pp. 301-323). United Kingdom: Academic Press.
2009 Jawahar, M., Wilson, Y., Lawrence, A., Brodnicki, T., & Murphy, M. (2009). Approaches to the Study of the Genetics of Behavioural Variation Using Mice and Rats. In L. Rechi (Ed.), Animal Genetics (pp. 55-79). Nova Science Pub Incorporated.
Year Citation 2015 Jawahar, M. C., Toben, C., Izzo, J., Heriot, N., Harrison, E., Murgatroyd, C., & Baune, B. T. (2015). The two-hit stress model:effect of early life stress and later life stressors on adult psychiatric disorders. Poster session presented at the meeting of Abstract. Brisbane. 2015 Jawahar, M. C., Toben, C., Izzo, J., Heriot, N., Harrison, E., Murgatroyd, C., & Baune, B. T. (2015). The two-hit stress model: effect of early life stress and later life stressors on adult psychiatric disorders. Poster session presented at the meeting of Society for Mental Health Research (SMHR) 2015. Brisbane.
Royal Adelaide Hospital (RAH) Research Committee- Clinical research grant: Associate investigator (AI-C). Title: To investigate the association of complement, oxidative and inflammatory markers and BDNF with cognitive and general function in chronic psychosis. $40,242 Jan 2019- June 2020
Royal Adelaide Hospital (RAH) Research Committee - Clinical research grant: CI-A. Title: Childhood maltreatment and adult depression status: A pilot study to identify neuro-immune interaction mechanisms mediating early adversity effects on adult depression. $43,772.84 Jan 2015 - Dec 2016
Lecturer: Fundamentals of Biological Psychiatry (PSYCHIAT3200): 2014-2015
Course coordinator: Fundamentals of Biological Psychiatry (PSYCHIAT3200): 2016-present
Module Co-Coordinator: Addiction and Mental Health Module; Reflect, Research and Resolve: 2018-present
Guest lecturer: Biological and Psychosocial Factors in Addiction: 2018-present
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2019 Co-Supervisor The Effects of Long-Term Exercise and Stopping Long-Term Exercise on Behaviours and Neurobiology Doctor of Philosophy Doctorate Full Time Ms Julie A Morgan 2015 - 2020 Co-Supervisor The Differential Effects of Short-Term Physical Exercise, Environmental Enrichment and their Combination, and Short-and-Long-Term Environmental Enrichment on Behavior and Associated Molecular Changes in the Brain of C57BL/6 Mice Doctor of Philosophy Doctorate Part Time Dr Gaurav Singhal
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