Mr Carl Coolen

Research Assistant

Centre for Cancer Biology

College of Health


Year Citation
2025 Subramaniam, S., Donnellan, L., Wignall, A., Woodcock, J., Coolen, C., Pitson, S., . . . Joyce, P. (2025). Polymeric-lipid nanoparticles that leverage cationic helper lipids and the protein corona for lung-targeted delivery of a novel anti-cancer drug. Journal of Controlled Release, 388(Pt 1), 15 pages.
DOI
2023 Yip, K. H., Chao, J., Coolen, C., Pant, H., Kral, A., Smith, W., . . . Tumes, D. J. (2023). IgE receptor of mast cells signals mediator release and inflammation via adaptor protein 14-3-3ζ. Journal of Allergy and Clinical Immunology, 152(3), 725-735.
DOI Scopus5 WoS5 Europe PMC3
2018 Woodcock, J., Goodwin, K., Sandow, J., Coolen, C., Perugini, M., Webb, A., . . . Carver, J. (2018). Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order, and molecular chaperone activity. Journal of Biological Chemistry, 293(1), 89-99.
DOI Scopus23 WoS23 Europe PMC20
2015 Pitman, M., Powell, J., Coolen, C., Moretti, P., Zebol, J., Pham, D., . . . Pitson, S. (2015). A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties. Oncotarget, 6(9), 7065-7083.
DOI Scopus65 WoS64 Europe PMC56
2015 Woodcock, J., Coolen, C., Goodwin, K., Baek, D., Bittman, R., Samuel, M., . . . Lopez, A. (2015). Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics. Oncotarget, 6(16), 14522-14536.
DOI Scopus34 WoS30 Europe PMC25
2010 Woodcock, J., Ma, Y., Coolen, C., Pham, D., Jones, C., Lopez, A., & Pitson, S. (2010). Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function. Cellular Signalling, 22(9), 1291-1299.
DOI Scopus65 WoS63 Europe PMC61
2008 Carr, J., Coolen, C., Davis, A., Burrell, C., & Li, P. (2008). Human immunodeficiency virus 1 (HIV-1) virion infectivity factor (Vif) is part of reverse transcription complexes and acts as an accessory factor for reverse transcription. Virology, 372(1), 147-156.
DOI Scopus22 WoS19 Europe PMC16
2007 Carr, J., Cheney, K., Coolen, C., Davis, A., Shaw, D., Ferguson, W., . . . Li, P. (2007). Development of methods for coordinate measurement of total cell-associated and integrated human immunodeficiency virus type 1 (HIV-1) DNA forms in routine clinical samples: levels are not associated with clinical parameters, but low levels of integrated HIV-1 DNA may be prognostic for continued successful therapy. Journal of Clinical Microbiology, 45(4), 1288-1297.
DOI Scopus23 WoS22 Europe PMC21
2006 Carr, J., Davis, A., Coolen, C., Cheney, K., Burrell, C., & Li, P. (2006). Vif-deficient HIV reverse transcription complexes (RTCs) are subject to structural changes and mutation of RTC-associated reverse transcription products. Virology, 351(1), 80-91.
DOI Scopus18 WoS17 Europe PMC12

Year Citation
2016 Woodcock, J., Lopez, A., Pitson, S., Samuel, M., & Coolen, C. (2016). WO2016054680, Modulators of 14-3-3 functionality and uses thereof.

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