Dr Briony Gliddon

Dr Briony Gliddon

Research Fellow

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Year Citation
2025 Mekonnen, L. B., Teo, T., Noll, B., Rahaman, M. H., Lenjisa, J., Basnet, S., . . . Wang, S. (2025). A brain-penetrant CDK4/6 inhibitor - AU3-14 shows robust anti-tumor efficacy against glioblastoma.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 189(118340), 118340.
DOI Europe PMC1
2024 Li, M., Bennett, M. K., Toubia, J., Pope, V. S., Tea, M. N., Tamang, S., . . . Pitson, S. M. (2024). An orthotopic syngeneic mouse model of bortezomib-resistant multiple myeloma. British Journal of Haematology, 204(2), 566-570.
DOI Scopus1 WoS1 Europe PMC1
2022 Lewis, A. C., Pope, V. S., Tea, M. N., Li, M., Nwosu, G. O., Nguyen, T. M., . . . Pitson, S. M. (2022). Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.. Blood, 139(26), 3737-3751.
DOI Scopus37 WoS32 Europe PMC35
2022 Gargett, T., Ebert, L. M., Truong, N. T. H., Kollis, P. M., Sedivakova, K., Yu, W., . . . Brown, M. P. (2022). GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma. Journal for ImmunoTherapy of Cancer, 10(9), 1-15.
DOI Scopus79 WoS79 Europe PMC75
2021 Duszyc, K., Gomez, G. A., Lagendijk, A. K., Yau, M. K., Nanavati, B. N., Gliddon, B. L., . . . Yap, A. S. (2021). Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. Current Biology, 31(6), 1326-1336.
DOI Scopus47 WoS46 Europe PMC47
2021 Bennett, M. K., Li, M., Tea, M. N., Pitman, M. R., Toubia, J., Wang, P. P. -S., . . . Pitson, S. M. (2021). Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition.. Neoplasia, 24(1), 1-11.
DOI Scopus16 WoS16 Europe PMC13
2019 Neubauer, H. A., Tea, M. N., Zebol, J. R., Gliddon, B. L., Stefanidis, C., Moretti, P. A. B., . . . Pitson, S. M. (2019). Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene, 38(8), 1151-1165.
DOI Scopus26 WoS24 Europe PMC18
2017 Zhu, W., Gliddon, B., Jarman, K., Moretti, P., Tin, T., Parise, L., . . . Pitson, S. (2017). CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1. Oncogene, 36(18), 2619-2627.
DOI Scopus29 WoS27 Europe PMC19
2017 Zhu, W., Jarman, K., Lokman, N., Neubauer, H., Davies, L., Gliddon, B., . . . Pitson, S. (2017). CIB2 negatively regulates oncogenic signaling in ovarian cancer via sphingosine kinase 1. Cancer Research, 77(18), 4823-4834.
DOI Scopus30 WoS26 Europe PMC26
2016 Clarke, J., Davies, L., Calvert, J., Gliddon, B., Al Shujari, W., Aloia, A., . . . Carr, J. (2016). Reduction in sphingosine kinase 1 influences the susceptibility to dengue virus infection by altering antiviral responses. Journal of General Virology, 97(1), 95-109.
DOI Scopus20 WoS17 Europe PMC17
2016 Neubauer, H. A., Pham, D. H., Zebol, J. R., Moretti, P. A. B., Peterson, A. L., Leclercq, T. M., . . . Pitson, S. M. (2016). An oncogenic role for sphingosine kinase 2. Oncotarget, 7(40), 64886-64899.
DOI Scopus54 WoS50 Europe PMC52
2015 Pitman, M., Powell, J., Coolen, C., Moretti, P., Zebol, J., Pham, D., . . . Pitson, S. (2015). A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties. Oncotarget, 6(9), 7065-7083.
DOI Scopus65 WoS64 Europe PMC56
2015 Parham, K., Zebol, J., Tooley, K., Sun, W., Moldenhauer, L., Cockshell, M., . . . Bonder, C. (2015). Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis. The FASEB Journal, 29(9), 3638-3653.
DOI Scopus82 WoS77 Europe PMC70
2014 Pham, D., Powell, J., Gliddon, B., Moretti, P., Tsykin, A., Van der Hoek, M., . . . Pitson, S. (2014). Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1. Oncogene, 33(48), 5559-5568.
DOI Scopus26 WoS25 Europe PMC23
2013 Nguyen, N., Kozer Gorevich, N., Gliddon, B. L., Smolka, A. J., Clayton, A. H., Gleeson, P. A., & van Driel, I. R. (2013). Independent trafficking of the KCNQ1 K+ channel and H+ -K+ -ATPase in gastric parietal cells from mice. American journal of physiology: gastrointestinal and liver physiology, 304(2), 157-166.
DOI
2011 Gunn, P. A., Gliddon, B. L., Londrigan, S. L., Lew, A. M., van Driel, I. R., & Gleeson, P. A. (2011). The Golgi apparatus in the endomembrane-rich gastric parietal cells exist as functional stable mini-stacks dispersed throughout the cytoplasm. Biology of the cell, 103(12), 559-572.
DOI
2011 Pitman, M., Barr, R., Gliddon, B., Magarey, A., Moretti, P., & Pitson, S. (2011). A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1. International Journal of Biochemistry & Cell Biology, 43(3), 342-347.
DOI Scopus23 WoS18 Europe PMC20
2008 Gliddon, B. L., Nguyen, N., Gunn, P., Gleeson, P., & Van, D. I. (2008). Isolation, culture and adenoviral transduction of parietal cells from mouse gastric mucosa. Biomedical materials, 3(3), 1-9.
DOI
2006 Crawley, A., Gliddon, B., Auclair, D., Brodie, S., Hirte, C., King, B., . . . Hopwood, J. (2006). Characterization of a C57BL/6 congenic mouse strain of mucopolysaccharidosis type IIIA. Brain Research, 1104(1), 1-17.
DOI Scopus94 WoS93 Europe PMC87
2004 Gliddon, B., Yogalingam, G., & Hopwood, J. (2004). Purification and characterization of recombinant murine sulfamidase. Molecular Genetics and Metabolism, 83(3), 239-245.
DOI Scopus9 WoS7 Europe PMC5
2004 Gliddon, B., & Hopwood, J. (2004). Enzyme-replacement therapy from birth delays the development of behavior and learning problems in mucopolysaccharidosis type IIIA mice. Pediatric Research, 56(1), 65-72.
DOI Scopus75 WoS67 Europe PMC60
2002 Yogalingam, G., Pollard, T., Gliddon, B., Jolly, R., & Hopwood, J. (2002). Identification of a mutation causing mucopolysaccharidosis type IIIA in New Zealand Huntaway dogs. Genomics, 79(2), 150-153.
DOI Scopus47 WoS38 Europe PMC34
2001 Bhattacharyya, R., Gliddon, B., Beccari, T., Hopwood, J., & Stanley, P. (2001). A novel missense mutation in lysosomal sulfamidase is the basis of MPS III A in a spontaneous mouse mutant. Glycobiology, 11(1), 99-103.
DOI Scopus72 WoS71 Europe PMC64

  • Harnessing an unexpected new role of the CD47:SPRPA axis to target glioblastome invasion, NHMRC - Ideas Grants, 01/01/2024 - 31/12/2027

  • Overcoming the blood-brain barrier for improved brain tumour therapy, Fay Fuller Foundation, 01/07/2024 - 30/06/2027

  • Understanding therapy-induced glioblastoma evolution to overcome treatment resistance, Neurosurgical Research Foundation, 01/01/2026 - 31/12/2026

  • Examining sphingosine kinase 2 as a therapeutic target in diffuse midline glioma, Neurosurgical Research Foundation, 08/10/2025 - 31/12/2026

  • Combined targeting of CD47 and cysteine metabolism to treat glioblastoma, Neurosurgical Research Foundation, 01/10/2024 - 31/03/2026

  • A new therapeutic approach for glioblastoma, Brain Foundation - Annual Research Awards, 01/01/2025 - 31/12/2025

  • Understanding the biology of treatment resistant brain tumours so that new therapeutic approaches can be developed, Neurosurgical Research Foundation, 04/07/2024 - 31/12/2025

  • Targeting sphingosine kinase 1 as a novel therapeutic strategy in childhood medulloblastoma, Neurosurgical Research Foundation, 01/10/2024 - 30/09/2025

  • Pre-clinical evaluation of sphingosine kinase 2 inhibitors as new glioblastoma therapeutics, Neurosurgical Research Foundation, 01/10/2024 - 30/09/2025

  • Harnessing S1P receptor 1 to enhance CAR-T cell immunotherapy, Neurosurgical Research Foundation, 30/08/2021 - 31/08/2022

  • Developing clinically relevant models of recurrent glioblastoma, Neurosurgical Research Foundation, 30/08/2021 - 31/08/2022

  • Targeting cyclin-dependent kinase 4 in glioblastoma, Neurosurgical Research Foundation, 24/08/2020 - 21/08/2021

Date Role Research Topic Program Degree Type Student Load Student Name
2025 External Supervisor A new therapeutic approach for the childhood brain tumour diffuse midline glioma Master of Philosophy Master Full Time Mr Ca Dat Pham
2025 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Sarmad Khan
2025 External Supervisor A new therapeutic approach for the childhood brain tumour diffuse midline glioma Master of Philosophy Master Full Time Mr Ca Dat Pham

Date Role Research Topic Program Degree Type Student Load Student Name
2010 - 2015 External Supervisor The Role of Sphingosine Kinases and SKAM1 in Cutaneous Wound Healing Doctor of Philosophy Doctorate Full Time Mr Huasheng Chan

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