Dr Brian Dale

Teaching Strengths

Haematology
Haemostasis
Transfusion Medicine
Real world experience
Work integrated learning

Dr Brian Dale

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Prior to moving to UniSA I gained extensive real-world experience as a medical laboratory scientist in haematology, transfusion medicine and haemostasis including senior scientist and managerial roles. I have a PhD in Medicine from the University of Western Australia and am a Fellow of the Australian Institute of Medical and Clinical Scientists (AIMS). I coordinate haematology and clinical practice courses in the Laboratory Medicine Program in Clinical and Health Sciences. As a member of the AIMS Program Accreditation Council I am involved with accreditation of Laboratory Medicine programs across Australia. My research is currently focussed on identifying contributors to thrombosis in haematological cancer.

Haematological malignancy and thrombosis, Platelet microparticle activity, Thrombin generation assays for the assessment of haemostasis, Global tests of haemostasis, New Diagnostic Tests and therapies,Thrombosis and bleeding disorders, Fibrin clot stability, Heparin induced thrombocytopenia

Year Citation
2023 Ross, D. M., Liang, H. P. H., Iqra, Z., Whittaker, S., Tan, C. W., Dale, B. J., & Chen, V. M. (2023). Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin.. Sci Rep, 13(1), 14 pages.
DOI Scopus14 WoS14 Europe PMC11
2021 Martini, C., DeNichilo, M., King, D. P., Cockshell, M. P., Ebert, B., Dale, B., . . . Bonder, C. S. (2021). CD36 promotes vasculogenic mimicry in melanoma by mediating adhesion to the extracellular matrix. BMC Cancer, 21(1), 765-1-765-14.
DOI Scopus29 WoS31 Europe PMC26
2020 Martini, C., Thompson, E. J., Hyslop, S. R., Cockshell, M. P., Dale, B. J., Ebert, L. M., . . . Bonder, C. S. (2020). Platelets disrupt vasculogenic mimicry by cancer cells. Scientific Reports, 10(1), 5869-1-5869-18.
DOI Scopus25 WoS21 Europe PMC21
2019 Waudby, H. P., Petit, S., Matthews, B., Sharp, A., Pradhan, R., & Dale, B. (2019). Investigation of ticks and red blood cell parasites of a population of reintroduced mainland tammar wallabies (Notamacropus eugenii eugenii). Australian mammalogy, 41(2), 269-272.
DOI Scopus2 WoS2
2018 Xu, K., Chan, N. C., Hirsh, J., Ginsberg, J. S., Bhagirath, V., Kruger, P., . . . Eikelboom, J. W. (2018). Quantifying immature platelets as markers of increased platelet production after coronary artery bypass grafting surgery. European journal of haematology, 101(3), 362-367.
DOI Scopus6 WoS6 Europe PMC4
2018 Kruger, P. C., Hirsh, J., Bhagirath, V. C., Xu, K., Dale, B., de Vries, T. A. C., . . . Chan, N. C. (2018). In vitro reversal of the anti-aggregant effect of ticagrelor using untreated platelets. Thrombosis and haemostasis, 118(11), 1895-1901.
DOI Scopus8 WoS8 Europe PMC5
2016 Dale, B. J., Chan, N. C., & Eikelboom, J. W. (2016). Laboratory measurement of the direct oral anticoagulants. British Journal of Haematology, 172(3), 315-336.
DOI Scopus93 WoS80 Europe PMC73
2015 Chan, N. C., Bhagirath, V., Dale, B. J., & Eikelboom, J. W. (2015). Evaluating coagulation tests in patients with atrial fibrillation using direct oral anticoagulants. Expert Review of Cardiovascular Therapy, 13(11), 1213-1223.
DOI Scopus1 WoS1 Europe PMC1
2014 Duncan, E., Dale, B., & Lloyd, J. (2014). Investigation of a link between raised levels of pepsinogen in blood as a mediator of in-vitro clot lysis in acid and a cause of abnormal factor XIII screening tests. Blood Coagulation & Fibrinolysis, 25(4), 340-348.
DOI Scopus5 WoS5 Europe PMC4
2014 Dale, B. J., Ginsberg, J. S., Johnston, M., Hirsh, J., Weitz, J. I., & Eikelboom, J. W. (2014). Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents. Journal of thrombosis and haemostasis, 12(11), 1810-1815.
DOI Scopus57 WoS56 Europe PMC46
2014 Rodgers, S. E., Wong, A., Gupal, R. D., Dale, B. J., Duncan, E. M., & McRae, S. J. (2014). Evaluation of pre-analytical variables in a commercial thrombin generation assay. Thrombosis research, 134(1), 160-164.
DOI Scopus42 WoS39 Europe PMC31
2012 Dale, B., Eikelboom, J. W., Weitz, J. I., Young, E., Paikin, J. S., Coppens, M., . . . Hirsh, J. (2012). Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?. Journal of thrombosis and thrombolysis, 35(2), 295-301.
DOI Scopus66 WoS62 Europe PMC51
2012 Arsenault, K. A., Paikin, J. S., Hirsh, J., Dale, B., Whitlock, R. P., Teoh, K., . . . Eikelboom, J. W. (2012). Subtle differences in commercial heparins can have serious consequences for cardiopulmonary bypass patients : a randomized controlled trial. Journal of thoracic and cardiovascular surgery, 144(4), 944-950.
DOI Scopus19 WoS16 Europe PMC13
2003 Dale, B. J. (2003). Platelets, Australian Journal of Medical Science, Book review. Australian Institute of Medical Scientists.

Courses I teach

  • MEDI 3012 Transfusion and Haemostasis (2024)
  • MEDI 4012 Advanced Clinical Practice A (2024)
  • MEDI 4013 Advanced Clinical Practice B (2024)

Programs I'm associated with

  • IHBL - Bachelor of Laboratory Medicine (Honours)

Date Role Research Topic Program Degree Type Student Load Student Name
2021 Principal Supervisor The Role of Platelet-Derived Microparticles and Mitochondria inMyeloproliferative Neoplasms (MPN) Doctor of Philosophy Doctorate Part Time Miss Zeenet Iqra

Date Role Research Topic Program Degree Type Student Load Student Name
2014 - 2018 Co-Supervisor The role of platelets in vasculogenic mimicry Doctor of Philosophy Doctorate Part Time Miss Carmela Martino
2006 - 2017 Principal Supervisor Laboratory assessment of factor XIII: impact of aspartic proteases and other influences on clot lysis and activity methods Doctor of Philosophy Doctorate Part Time Ms Elizabeth Duncan
2005 - 2009 Principal Supervisor Development and evaluation of a novel flurometric microsphere platelet antibody detection method (FM-PAD) for the identification and quantitation of anti-HPA-1a platelet antibodies Master of Science (Laboratory Medicine) Master Part Time Mrs Natalie Villalta

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