Asif Chinnaratha

Asif Chinnaratha

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Asif Chinnaratha
MBBS MRCP(UK) FRACP FRCP(Glasg) PhD
Gastroenterologist/Hepatologist

Dr Chinnaratha completed his basic physician training in Western Australia in 2010. He commenced his advanced training in Gastroenterology in 2011 and was awarded Fellowship of the Royal Australasian College of Physicians in 2013. He completed another year of sub-speciality training in hepatology with the Liver Transplant unit at Flinders Medical Centre.

He completed his PhD with the Flinders University of South Australia exploring the effect of hepatitis B viral infection and its complications in South Australia.

Dr Asif Chinnaratha is a senior consultant Gastroenterologist/ hepatologist and also the co-lead in hepatology at the Northern Adelaide Local Health Network (NALHN). He has a special interest in clinical hepatology; in particular, hepatocellular carcinoma, alcoholic hepatitis and viral hepatitis. In addition to this, he also provides a general gastroenterology service at the hospital.

Research interests:

Hepatocellualr carcinoma

Alcoholic hepatitis

Portal hypertension

Viral hepatitis

  • Language Competencies
    Language Competency
    Arabic Can read and write
    English Can read, write, speak, understand spoken and peer review
    Tamil Can read, write, speak, understand spoken and peer review

  • Certifications
    Date Title Institution name Country
    — Abdominal Ultrasound workshop Australian School of Medical Imaging (NSW) -
    — Statistics in Medicine Stanford University School of Medicine United States

  • Research Interests
    Gastroenterology and Hepatology

  • Journals
    Year Citation
    2024 Tan, J. L., Lokan, T., Chinnaratha, M. A., & Veysey, M. (2024). Risk of bleeding after abdominal paracentesis in patients with chronic liver disease and coagulopathy: A systematic review and meta-analysis. JGH Open, 8(8), 7 pages.
    DOI
    2024 Tan, J. L., Heng, K., Chinnaratha, M. A., Bulamu, N. B., Kaambwa, B., & Singh, R. (2024). Incidence rates of Barrett's esophagus and esophageal adenocarcinoma: a systematic review and meta-analysis. iGIE, 3(1), 92-103.e3.
    DOI
    2024 Tan, J. L., Pitawela, D., Chinnaratha, M. A., Beany, A., Aguila, E. J., Chen, H. T., . . . Singh, R. (2024). Exploring vision transformers for classifying early Barrett's dysplasia in endoscopic images: A pilot study on white-light and narrow-band imaging. JGH Open, 8(9), e70030.
    DOI
    2023 Tan, J. L., Sidhu-Brar, S., Woodman, R., & Chinnaratha, M. A. (2023). Regular Aspirin Use Is Associated with a Reduced Risk of Hepatocellular Carcinoma (HCC) in Chronic Liver Disease: a Systematic Review and Meta-analysis. Journal of Gastrointestinal Cancer, 54(2), 325-331.
    DOI Scopus6 WoS4 Europe PMC4
    2022 Tan, J. L., Chinnaratha, M. A., Woodman, R., Martin, R., Chen, H. -T., Carneiro, G., & Singh, R. (2022). Diagnostic Accuracy of Artificial Intelligence (AI) to Detect Early Neoplasia in Barrett's Esophagus: A Non-comparative Systematic Review and Meta-Analysis. Frontiers in Medicine, 9, 1-11.
    DOI Scopus5 WoS2 Europe PMC5
    2022 Loo, K. F., Woodman, R. J., Bogatic, D., Chandran, V., Muller, K., Chinnaratha, M. A., . . . Wigg, A. (2022). High rates of treatment stage migration for early hepatocellular carcinoma and association with adverse outcomes: An Australian multicenter study. JGH Open, 6(9), 599-606.
    DOI Scopus2 Europe PMC3
    2022 Au, M., Smart, C., & Chinnaratha, M. A. (2022). A Rare Neurological Complication in Advanced Liver Disease: Acquired Hepatocerebral Degeneration. American Journal of the Medical Sciences, 363(4), e37-e38.
    DOI Scopus1 Europe PMC1
    2022 Rose, P. D., Au, M., Woodman, R. J., Tee, D., & Chinnaratha, M. A. (2022). Erratum to: “Pre-procedural use of thrombopoietin-receptor agonists in cirrhosis and severe thrombocytopenia: A systematic review and meta-analysis” [Dig. Liver Dis. 2021;53:1396–1403] (Digestive and Liver Disease (2021) 53(11) (1396–1403), (S1590865821003844), (10.1016/j.dld.2021.07.015)). Digestive and Liver Disease, 54(1), 149.
    DOI
    2022 Chandran, V., Rajandran, A., Loo, K. F., Bate, J., Wigg, A. J., & Chinnaratha, M. A. (2022). The Face of Hepatocellular Carcinoma (
    HCC
    ) is Changing: Analysis of the temporal trends in aetiology and clinical patterns of
    HCC
    in South Australia. Internal Medicine Journal, 53(7), 1131-1136.
    DOI Scopus2
    2021 Rose, P. D., Au, M., Woodman, R. J., Tee, D., & Chinnaratha, M. A. (2021). Pre-procedural use of thrombopoietin-receptor agonists in cirrhosis and severe thrombocytopenia: A systematic review and meta-analysis. Digestive and Liver Disease, 53(11), 1396-1403.
    DOI Scopus8 WoS4 Europe PMC2
    2020 Chan, A., Philpott, H., Lim, A. H., Au, M., Tee, D., Harding, D., . . . Singh, R. (2020). Anticoagulation and antiplatelet management in gastrointestinal endoscopy: A review of current evidence. WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY, 12(11), 43 pages.
    DOI
    2020 Ramachandran, J., Kaambwa, B., Muller, K., Haridy, J., Tse, E., Tilley, E., . . . Wigg, A. J. (2020). Cost effectiveness of treatment models of care for hepatitis C: the South Australian state-wide experience. European Journal of Gastroenterology and Hepatology, 32(10), 1381-1389.
    DOI Scopus3 WoS3 Europe PMC1
    2019 Chinnaratha, M. A., Campbell, K., Mathias, R., McCormick, R. J., Woodman, R. J., & Wigg, A. J. (2019). Improved Survival of Hepatocellular Carcinoma Patients Diagnosed with a Dedicated Screening Programme—a Propensity Score Adjusted Analysis. Journal of Gastrointestinal Cancer, 50(4), 888-893.
    DOI Scopus5 WoS4 Europe PMC2
    2019 Gill, M., Tee, D., & Chinnaratha, M. A. (2019). Caustic ingestion: Has the role of the gastroenterologist burnt out?. EMA - Emergency Medicine Australasia, 31(3), 479-482.
    DOI Scopus8 WoS7 Europe PMC1
    2019 Wigg, A. J., Narayana, S. K., Le, H., Iankov, I., Chinnaratha, M. A., Tse, E., . . . Gowda, R. (2019). Stereotactic body radiation therapy for early hepatocellular carcinoma: a retrospective analysis of the South Australian experience. ANZ Journal of Surgery, 89(9), 1138-1143.
    DOI Scopus4 WoS4 Europe PMC2
    2018 Hall, S. A. L., Shaikh, A., Teh, K., Tantiongco, M., Coghlan, D., Karapetis, C. S., . . . Wigg, A. J. (2018). Hepatitis B screening before rituximab therapy: a multicentre South Australian study of adherence. Internal Medicine Journal, 48(8), 936-943.
    DOI Scopus8 WoS5 Europe PMC2
    2018 Chandran, V., Neo, E. L., & Chinnaratha, M. A. (2018). Rare Presentation of Intraductal Papillary Neoplasm of the Bile Duct in a Patient With Ulcerative Colitis. Clinical Gastroenterology and Hepatology, 16(10), A38-A39.
    DOI
    2018 Haridy, J., Wigg, A., Muller, K., Ramachandran, J., Tilley, E., Waddell, V., . . . Tse, E. (2018). Real-world outcomes of unrestricted direct-acting antiviral treatment for hepatitis C in Australia: The South Australian statewide experience. Journal of Viral Hepatitis, 25(11), 1287-1297.
    DOI Scopus28 WoS24 Europe PMC16
    2017 Chinnaratha, M. A., Kaambwa, B., Woodman, R. J., Fraser, R. J., & Wigg, A. J. (2017). Assessing the clinical and economic impact of increasing treatment uptake in chronic hepatitis B infection using a Markov model.. Journal of gastroenterology and hepatology, 32(7), 1370-1377.
    DOI Scopus4 WoS4 Europe PMC3
    2017 Foo, T., & Chinnaratha, M. A. (2017). Gastrointestinal: Unusual endoscopic finding in a patient with dysphagia and gastro-esophageal reflux. Journal of Gastroenterology and Hepatology (Australia), 32(10), 1665.
    DOI
    2016 Pateria, P., Jeffrey, G., Macquillan, G., Speers, D., Ching, H., Chinnaratha, M., . . . Adams, L. (2016). The association between chronic hepatitis C infection and cardiovascular risk. Internal Medicine Journal, 46(1), 63-70.
    DOI Scopus15 WoS14 Europe PMC9
    2016 Chinnaratha, M. A., Graham, C., Fraser, R. J. L., Woodman, R. J., & Wigg, A. J. (2016). Rising incidence of hepatitis B-related hepatocellular carcinoma in South Australia: 1996–2010. Internal Medicine Journal, 46(8), 902-908.
    DOI Scopus4 WoS4 Europe PMC3
    2016 Pateria, P., Jeffrey, G. P., MacQuillan, G., Speers, D., Ching, H., Chinnaratha, M. A., . . . Adams, L. A. (2016). Author reply. Internal Medicine Journal, 46(7), 863.
    DOI
    2016 Chinnaratha, M., Chuang, M., Fraser, R., Woodman, R., & Wigg, A. (2016). Percutaneous thermal ablation for primary hepatocellular carcinoma: A systematic review and meta-analysis. Journal of Gastroenterology and Hepatology, 31(2), 294-301.
    DOI Scopus84 WoS71 Europe PMC49
    2015 Chuang, M., Chinnaratha, M., Hancock, D., Woodman, R., Biostats, M., Wong, G., . . . Fraser, R. (2015). Topical steroid therapy for the treatment of eosinophilic esophagitis (EoE): a systematic review and meta-analysis. Clinical and Translational Gastroenterology, 6(3), e82-1-e82-9.
    DOI Scopus78 WoS58 Europe PMC46
    2015 Chinnaratha, M., Chaudhary, S., Doogue, M., Mccormick, R., Woodman, R., & Wigg, A. (2015). Prevalence of hepatic osteodystrophy and vitamin D deficiency in cirrhosis. Internal Medicine Journal, 45(12), 1230-1235.
    DOI Scopus18 WoS15 Europe PMC10
    2015 Chinnaratha, M., Sathananthan, D., Pateria, P., Tse, E., Macquillan, G., Mosel, L., . . . Wigg, A. (2015). High local recurrence of early-stage hepatocellular carcinoma after percutaneous thermal ablation in routine clinical practice. European Journal of Gastroenterology and Hepatology, 27(3), 349-354.
    DOI Scopus25 WoS25 Europe PMC18
    2015 Wigg, A. J., Chinnaratha, M. A., Wundke, R., & Volk, M. L. (2015). A chronic disease management model for chronic liver failure. Hepatology, 61(2), 725-728.
    DOI Scopus7 WoS6 Europe PMC4
    2014 Chinnaratha, M., Chelvaratnam, U., Stuart, K., Strasser, S., McCaughan, G., Gow, P., . . . Wigg, A. (2014). Liver transplantation outcomes for Australian Aboriginal and Torres Strait Islanders. Liver Transplantation, 20(7), 798-806.
    DOI Scopus6 WoS4 Europe PMC3
    2014 Chinnaratha, M., Jeffrey, G., Macquillan, G., Rossi, E., de Boer, B., Speers, D., & Adams, L. (2014). Prediction of morbidity and mortality in patients with chronic hepatitis C by non-invasive liver fibrosis models. Liver International, 34(5), 720-727.
    DOI Scopus24 WoS22 Europe PMC16
    2014 Chinnaratha, M. A., & Khor, T. S. (2014). An unusual malformation predisposing to liver tumors. Clinical Gastroenterology and Hepatology, 12(1), XXXVIII-XXXIX.
    DOI
    2014 Chinnaratha, M. A., Mccormick, R., Wundke, R., Woodman, R. J., & Wigg, A. J. (2014). Prevalence of bone disease in cirrhosis. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, 71.
    2014 Chuang, M. A., Chinnaratha, M. A., Woodman, R., Cock, C., & Fraser, R. (2014). Topical steroid therapy for the treatment of eosinophilic esophagitis (EoE) - A systematic review and meta-analysis. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, 125.
    2013 Chinnaratha, M. A., Venugopal, K., de Boer, W. B., & Macquillan, G. (2013). Novel mutation in progressive familial intrahepatic cholestasis III. Liver International, 33(8), 1293.
    DOI Scopus1 WoS1 Europe PMC1
    2010 Chinnaratha, M. A., Le-Ha, C., Beilin, L., Ayonrinde, O. T., Olynyk, J. K., Mori, T., . . . Adams, L. A. (2010). Relationship between non-alcoholic fatty liver disease, vascular risk factors and arterial stiffness in adolescents. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A33-A34.
    2010 Chinnaratha, M. A., Watts, G., Ching, H., Jeffrey, G. P., Macquillan, G., Speers, D., . . . Adams, L. A. (2010). Chronic hepatitis C infection and sub-clinical vascular disease. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A127.
    2007 Chinnaratha, M. A., Criddle, R. A., & Graziotti, P. J. (2007). Spontaneous intracranial hypotension: An easily treated headache [10]. Medical Journal of Australia, 187(1), 59.
    DOI Scopus1 WoS1 Europe PMC5

  • Conference Items
    Year Citation
    2020 Loo, K. F., Woodman, R., Bogatic, D., Muller, K., Chandran, V., Chinnaratha, M. A., . . . Wigg, A. (2020). Treatment stage migration for early hepatocellular carcinoma and its impact on outcomes: A multicenter study. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
    2020 Au, M., Chinnaratha, M. A., & Harding, D. (2020). Impact of COVID-19 on alcohol-related liver disease: An emerging public health issue in Australia. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
    WoS1
    2020 Rose, P., Au, M., Woodman, R., Tee, D., & Chinnaratha, M. A. (2020). Thrombopoietin-receptor agonists for patients with cirrhosis and severe thrombocytopenia undergoing invasive procedures: A systematic review and meta-analysis. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
    2020 Rose, P., Au, M., Woodman, R., Teel, D., & Chinnaratha, M. A. (2020). THROMBOPOIETIN-RECEPTOR AGONISTS FOR PATIENTS WITH CIRRHOSIS AND SEVERE THROMBOCYTOPAENIA UNDERGOING INVASIVE PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Poster session presented at the meeting of HEPATOLOGY. ELECTR NETWORK: WILEY.
    2020 Loo, K. F., Woodman, R., Bogatic, D., Muller, K., Chandran, V., Chinnaratha, M. A., . . . Wigg, A. (2020). TREATMENT STAGE MIGRATION FOR EARLY HCCs AND ITS IMPACT ON OUTCOMES- A MULTI-CENTRE STUDY. Poster session presented at the meeting of HEPATOLOGY. ELECTR NETWORK: WILEY.
    2017 Zhou, J. Y., Chinnaratha, M. A., Woodman, R. J., & Wigg, A. J. (2017). The influence of a chronic liver failure program on variceal rebleeding rates: A multicenter study. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
    2017 Wigg, A. J., Muller, K. R., Teo, M., Rodgers, A., Mounkley, D., Chinnaratha, M. A., . . . Gowda, R. (2017). Stereotactic ablative body radiotherapy for early hepatocellular carcinoma: A promising early South Australian experience. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
    2014 Chinnaratha, M., Chuang, A., Fraser, R., Woodman, R., & Wigg, A. (2014). Percutaneous thermal ablation for hepatocellular carcinoma: A systematic review and meta-analysis. Poster session presented at the meeting of HEPATOLOGY. Boston, MA: WILEY-BLACKWELL.
    2014 Chinnaratha, M., Chuang, M. -Y., Fraser, R., Woodman, R., & Wigg, A. (2014). Percutaneous thermal ablation for primary hepatocellular carcinoma: a systematic review and meta-analysis. Poster session presented at the meeting of Abstracts of the Australian Gastroenterology Week 2014, as published in Journal of Gastroenterology and Hepatology. Broadbeach, QLD: Wiley-Blackwell.
    DOI
    2013 Chinnaratha, M. A., Chelvaratnam, U., Stuart, K. A., Strasser, S., Mccaughan, G., Gow, P., . . . Wigg, A. J. (2013). Liver transplant outcomes in an aboriginal and torres strait islander population. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL.
    2013 Chinnaratha, M. A., Sathananthan, D., Pateria, P., Tse, E., MacQuillan, G. C., Tibballs, J., & Wigg, A. J. (2013). Predictors of Hepatocellular carcinoma recurrence post thermal ablation. Poster session presented at the meeting of HEPATOLOGY. Washington, DC: WILEY-BLACKWELL.
    2013 Chinnaratha, M. A., Sathananthan, D., Pateria, P., Tse, E., Macquillan, G., & Wigg, A. J. (2013). Predictors of hepatocellular carcinoma recurrence post thermal ablation. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Melbourne, Vic.: Wiley.
    DOI
    2012 Chinnaratha, M. A., Rajakaruna, G., & Ayonrinde, O. T. (2012). Timing of variceal haemorrhage in patients with cirrhosis - is there a circadian variation?. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.

  • Report for External Bodies
    Year Citation
    - Pakuwal, E., Hargreaves, B., Moradi, M., Page, A. J., Chinnaratha, M. A., & Stringer, A. M. (n.d.). The Efficacy of Microbiome-Targeted Therapy in Modulating Gut Health in Alcohol-Induced Liver Injury: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols.
    DOI

2023     RACP research establishment fellowship for the project titled: “GENESIS: Qualitative gut microbiome assessment and the role of faecal microbiota transplantation in severe alcoholic hepatitis” (Principal Investigator: MA Chinnaratha). [Amount awarded: AU$50,000 for 12 months]

2019     NHMRC partnership grant (GN1170032) for the project titled: “Implementation of a chronic disease management model in chronic liver failure patients to improve rates of emergency admissions providing an opportunity to drive practice change” (Chief Investigator A: Alan Wigg; Associate Investigator: MA Chinnaratha). [Amount awarded: $ 452,000 (NHMRC), $ 592,000 (Partners), total=$ 1,064,000 for 3 years]

2014     Australian Postgraduate Award from Flinders University for the project titled: “Hepatocellular carcinoma incidence and mortality in chronic hepatitis B and the economic burden of chronic hepatitis B in South Australia” (Principal Investigator: MA Chinnaratha) [Amount awarded: $25,392/annum for 3 years]

2013     Seeding grant from the Flinders Medical Centre foundation for the project titled “Predictors of hepatocellular carcinoma recurrence post thermal ablation” (Chief Investigators: MA Chinnaratha and AJ Wigg) [Amount awarded: $10,000 for 1 year]

Seeding grant from the Flinders Medical Centre foundation for the project titled “Liver transplant outcomes in Aboriginal and Torres Strait Islanders” (Chief Investigators: MA Chinnaratha and AJ Wigg) [Amount awarded: $14,000 for 1 year]

I have a keen in interest in teaching and supervising medical students and trainees. Currently, co-supervising a Masters candidate at the University of Adelaide who is nearing completion. Papers arising out of his work so far include: 'Diagnostic Accuracy of Artificial Intelligence (AI) to Detect Early Neoplasia in Barrett's Esophagus: A Non-comparative Systematic Review and Meta-Analysis'. Tan JL, Chinnaratha MA et al., Front Med (Lausanne). 2022 Jun 22;9:890720. doi: 10.3389/fmed.2022.890720. eCollection 2022.

College (RACP) approved supervisor for Gastroenterology advanced trainees (AT). I have supervised 3 Gastroenterology ATs to successful completion of their college project (mandatory training requirement). Papers arising out of these projects include:

2017 - 'ALBI grade better stratifies risk of clinical decompensation in patients with compensated cirrhosis' Shaikh, A. [...] Chinnaratha MA.

2019 - Hepatocellular carcinoma (HCC) is changing its face: analysis of the temporal trends in aetiology and clinical patterns of HCC in South Australia. Chandran, V. [...] Chinnaratha MA.

2022 - Real world outcomes of patients with advanced hepatocellular carcinoma on Atezolizumab and Bevacizumab. Chan, A. [...] Chinnaratha MA.

  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2023 Co-Supervisor Artificial Intelligence and Endoscopy - Enhancing early detection and improving outcomes in dysplasia and cancer of the Upper Gastrointestinal Tracts. Doctor of Philosophy Doctorate Full Time Mr Jin Lin Tan
    2023 Principal Supervisor Qualitative gut microbiome assessment and the role of faecal microbiota transplantation (FMT) in Severe alcoholic hepatitis (sAH) Doctor of Philosophy Doctorate Full Time Miss Evance Pakuwal

  • Memberships
    Date Role Membership Country
    2009 - ongoing Member Australian Liver Association Australia
    2009 - ongoing Member Gastroenterology Society of Australia (GESA) Australia
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