Andrew Barrow
Waite Research Institute
Division of Research and Innovation
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Andrew Barrow is a postdoctoral researcher in the Soares da Costa laboratory and his research is mainly focused on the design and synthesis of novel small molecules for use as herbicidal scaffolds.
Dr Barrow obtained his PhD in Chemistry from the University of Nottingham, under the supervision of Professor John Moses, where his research centred around the development of photoactive chemical probes for protein footprinting, a technique designed to elucidate information about protein-protein interactions. He relocated with the Moses group to La Trobe University, Melbourne to undertake postdoctoral research in the emerging field of SuFEx click chemistry, particularly in the synthesis of heterocycles decorated with click handles.
Following his time at La Trobe University, Dr Barrow held a short-term research position in the group of Professor David Procter at the University of Manchester, exploring asymmetric catalysis before returning to Australia to join the Soares da Costa laboratory at the University of Adelaide.
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Appointments
Date Position Institution name 2022 - ongoing Grant Funded Researcher University of Adelaide 2021 - 2021 Research Associate University of Manchester 2017 - 2021 Research Officer La Trobe University -
Education
Date Institution name Country Title 2012 - 2016 University of Nottingham United Kingdom PhD 2008 - 2012 University of Bath United Kingdom MChem
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Journals
Year Citation 2024 Homer, J. A., Koelln, R. A., Barrow, A. S., Gialelis, T. L., Boiarska, Z., Steinohrt, N. S., . . . Moses, J. E. (2024). Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15(11), 3879-3892.
Scopus8 Europe PMC22023 Mackie, E. R. R., Barrow, A. S., Giel, M. -C., Hulett, M. D., Gendall, A. R., Panjikar, S., & Soares da Costa, T. P. (2023). Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity. Communications Biology, 6(1), 1-11.
Scopus2 Europe PMC32022 Smedley, C. J., Homer, J. A., Gialelis, T. L., Barrow, A. S., Koelln, R. A., & Moses, J. E. (2022). Accelerated SuFEx Click Chemistry For Modular Synthesis**. Angewandte Chemie - International Edition, 61(4), 8 pages.
Scopus85 WoS33 Europe PMC392022 Mackie, E. R. R., Barrow, A. S., Christoff, R. M., Abbott, B. M., Gendall, A. R., & Soares da Costa, T. P. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis. eLife, 11, 1-11.
Scopus6 WoS4 Europe PMC42022 Wyllie, J. A., McKay, M. V., Barrow, A. S., & Soares da Costa, T. P. (2022). Biosynthesis of uridine diphosphate N-Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?. IUBMB life, 71(12), 1232-1252.
Scopus12 WoS5 Europe PMC72021 Giel, M. C., Barrow, A. S., Smedley, C. J., Lewis, W., & Moses, J. E. (2021). Aminium cation-radical catalysed selective hydration of (E)-aryl enynes. Chemical Communications, 57(57), 6991-6994.
Scopus6 WoS3 Europe PMC32020 Smedley, C. J., Li, G., Barrow, A. S., Gialelis, T. L., Giel, M. C., Ottonello, A., . . . Moses, J. E. (2020). Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angewandte Chemie - International Edition, 59(30), 12460-12469.
Scopus95 WoS61 Europe PMC362019 Barrow, A. S., Smedley, C. J., Zheng, Q., Li, S., Dong, J., & Moses, J. E. (2019). The growing applications of SuFEx click chemistry. Chemical Society Reviews, 48(17), 4731-4758.
Scopus389 WoS233 Europe PMC1402018 Randall, J. D., Eyckens, D. J., Stojcevski, F., Francis, P. S., Doeven, E. H., Barlow, A. J., . . . Henderson, L. C. (2018). Modification of Carbon Fibre Surfaces by Sulfur-Fluoride Exchange Click Chemistry. ChemPhysChem, 19(23), 3176-3181.
Scopus40 WoS28 Europe PMC92018 Smedley, C. J., Stanley, P. A., Qazzaz, M. E., Prota, A. E., Olieric, N., Collins, H., . . . Moses, J. E. (2018). Sustainable Syntheses of (-)-Jerantinines A & e and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Scientific Reports, 8(1), 7 pages.
Scopus11 WoS9 Europe PMC92018 Smedley, C. J., Giel, M. C., Molino, A., Barrow, A. S., Wilson, D. J. D., & Moses, J. E. (2018). 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry. Chemical Communications, 54(47), 6020-6023.
Scopus72 WoS58 Europe PMC182018 Jenner, M., Kosol, S., Griffiths, D., Prasongpholchai, P., Manzi, L., Barrow, A. S., . . . Challis, G. L. (2018). Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases. Nature Chemical Biology, 14(3), 270-275.
Scopus27 WoS21 Europe PMC242017 Manzi, L., Barrow, A. S., Hopper, J. T. S., Kaminska, R., Kleanthous, C., Robinson, C. V., . . . Oldham, N. J. (2017). Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angewandte Chemie - International Edition, 56(47), 14873-14877.
Scopus33 WoS26 Europe PMC262017 Smedley, C. J., Barrow, A. S., Spiteri, C., Giel, M. C., Sharma, P., & Moses, J. E. (2017). Sulfur–Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates. Chemistry - A European Journal, 23(42), 9990-9995.
Scopus40 WoS33 Europe PMC92016 Stanley, P. A., Spiteri, C., Moore, J. C., Barrow, A. S., Sharma, P., & Moses, J. E. (2016). Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design, 22(12), 1628-1657.
Scopus10 WoS9 Europe PMC32016 Barrow, A. S., & Moses, J. E. (2016). Synthesis of Sulfonyl Azides via Lewis Base Activation of Sulfonyl Fluorides and Trimethylsilyl Azide. Synlett, 27(12), 1840-1843.
Scopus31 WoS242016 Manzi, L., Barrow, A. S., Scott, D., Layfield, R., Wright, T. G., Moses, J. E., & Oldham, N. J. (2016). Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions. Nature Communications, 7(1), 9 pages.
Scopus58 WoS53 Europe PMC49
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2025 Co-Supervisor Structural and functional characterisation of protein targets to guide the design of novel herbicides Master of Philosophy Master Full Time Mr Chaudhry Artemiy Razovich Hussnain
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