Dr Andrew Barrow
ARC Grant-Funded Researcher (A)
School of Agriculture, Food and Wine
College of Science
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Andrew Barrow is a postdoctoral researcher in the Soares da Costa laboratory and his research is mainly focused on the design and synthesis of novel small molecules for use as herbicidal scaffolds.Dr Barrow obtained his PhD in Chemistry from the University of Nottingham, under the supervision of Professor John Moses, where his research centred around the development of photoactive chemical probes for protein footprinting, a technique designed to elucidate information about protein-protein interactions. He relocated with the Moses group to La Trobe University, Melbourne to undertake postdoctoral research in the emerging field of SuFEx click chemistry, particularly in the synthesis of heterocycles decorated with click handles.Following his time at La Trobe University, Dr Barrow held a short-term research position in the group of Professor David Procter at the University of Manchester, exploring asymmetric catalysis before returning to Australia to join the Soares da Costa laboratory at the University of Adelaide.
| Date | Position | Institution name |
|---|---|---|
| 2022 - ongoing | Grant Funded Researcher | University of Adelaide |
| 2021 - 2021 | Research Associate | University of Manchester |
| 2017 - 2021 | Research Officer | La Trobe University |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2012 - 2016 | University of Nottingham | United Kingdom | PhD |
| 2008 - 2012 | University of Bath | United Kingdom | MChem |
| Year | Citation |
|---|---|
| 2025 | Mackie, E. R. R., Mckay, M. V., Barrow, A. S., & da Costa, T. P. S. (2025). Inhibitors of lysine biosynthesis enzymes as potential new herbicides. Functional Plant Biology, 52(5), FP25030-1-FP25030-13. |
| 2024 | Homer, J. A., Koelln, R. A., Barrow, A. S., Gialelis, T. L., Boiarska, Z., Steinohrt, N. S., . . . Moses, J. E. (2024). Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15(11), 3879-3892. Scopus13 WoS13 Europe PMC4 |
| 2023 | Mackie, E. R. R., Barrow, A. S., Giel, M. -C., Hulett, M. D., Gendall, A. R., Panjikar, S., & Soares da Costa, T. P. (2023). Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity. Communications Biology, 6(1), 1-11. Scopus3 WoS3 Europe PMC4 |
| 2022 | Smedley, C. J., Homer, J. A., Gialelis, T. L., Barrow, A. S., Koelln, R. A., & Moses, J. E. (2022). Accelerated SuFEx Click Chemistry For Modular Synthesis**. Angewandte Chemie - International Edition, 61(4), 8 pages. Scopus98 WoS101 Europe PMC58 |
| 2022 | Mackie, E. R. R., Barrow, A. S., Christoff, R. M., Abbott, B. M., Gendall, A. R., & Soares da Costa, T. P. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis. eLife, 11, 1-11. Scopus8 WoS7 Europe PMC6 |
| 2022 | Wyllie, J. A., McKay, M. V., Barrow, A. S., & Soares da Costa, T. P. (2022). Biosynthesis of uridine diphosphate N-Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?. IUBMB life, 71(12), 1232-1252. Scopus13 WoS11 Europe PMC12 |
| 2021 | Giel, M. C., Barrow, A. S., Smedley, C. J., Lewis, W., & Moses, J. E. (2021). Aminium cation-radical catalysed selective hydration of (E)-aryl enynes. Chemical Communications, 57(57), 6991-6994. Scopus6 WoS5 Europe PMC4 |
| 2020 | Smedley, C. J., Li, G., Barrow, A. S., Gialelis, T. L., Giel, M. C., Ottonello, A., . . . Moses, J. E. (2020). Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angewandte Chemie - International Edition, 59(30), 12460-12469. Scopus110 WoS111 Europe PMC59 |
| 2019 | Barrow, A. S., Smedley, C. J., Zheng, Q., Li, S., Dong, J., & Moses, J. E. (2019). The growing applications of SuFEx click chemistry. Chemical Society Reviews, 48(17), 4731-4758. Scopus456 WoS449 Europe PMC276 |
| 2018 | Randall, J. D., Eyckens, D. J., Stojcevski, F., Francis, P. S., Doeven, E. H., Barlow, A. J., . . . Henderson, L. C. (2018). Modification of Carbon Fibre Surfaces by Sulfur-Fluoride Exchange Click Chemistry. ChemPhysChem, 19(23), 3176-3181. Scopus43 WoS42 Europe PMC16 |
| 2018 | Smedley, C. J., Stanley, P. A., Qazzaz, M. E., Prota, A. E., Olieric, N., Collins, H., . . . Moses, J. E. (2018). Sustainable Syntheses of (-)-Jerantinines A & e and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Scientific Reports, 8(1), 7 pages. Scopus11 WoS13 Europe PMC10 |
| 2018 | Smedley, C. J., Giel, M. C., Molino, A., Barrow, A. S., Wilson, D. J. D., & Moses, J. E. (2018). 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry. Chemical Communications, 54(47), 6020-6023. Scopus79 WoS79 Europe PMC37 |
| 2018 | Jenner, M., Kosol, S., Griffiths, D., Prasongpholchai, P., Manzi, L., Barrow, A. S., . . . Challis, G. L. (2018). Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases. Nature Chemical Biology, 14(3), 270-275. Scopus28 WoS30 Europe PMC31 |
| 2017 | Manzi, L., Barrow, A. S., Hopper, J. T. S., Kaminska, R., Kleanthous, C., Robinson, C. V., . . . Oldham, N. J. (2017). Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angewandte Chemie - International Edition, 56(47), 14873-14877. Scopus34 WoS33 Europe PMC30 |
| 2017 | Smedley, C. J., Barrow, A. S., Spiteri, C., Giel, M. C., Sharma, P., & Moses, J. E. (2017). Sulfur–Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates. Chemistry - A European Journal, 23(42), 9990-9995. Scopus45 WoS44 Europe PMC22 |
| 2016 | Stanley, P. A., Spiteri, C., Moore, J. C., Barrow, A. S., Sharma, P., & Moses, J. E. (2016). Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design, 22(12), 1628-1657. Scopus10 WoS10 Europe PMC5 |
| 2016 | Barrow, A. S., & Moses, J. E. (2016). Synthesis of Sulfonyl Azides via Lewis Base Activation of Sulfonyl Fluorides and Trimethylsilyl Azide. Synlett, 27(12), 1840-1843. Scopus34 WoS32 |
| 2016 | Manzi, L., Barrow, A. S., Scott, D., Layfield, R., Wright, T. G., Moses, J. E., & Oldham, N. J. (2016). Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions. Nature Communications, 7(1), 9 pages. Scopus61 WoS64 Europe PMC58 |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | Structural and functional characterisation of protein targets to guide the design of novel herbicides | Master of Philosophy | Master | Full Time | Chaudhry Artemiy Hussnain |
| 2025 | Co-Supervisor | Structural and functional characterisation of protein targets to guide the design of novel herbicides | Master of Philosophy | Master | Full Time | Chaudhry Artemiy Hussnain |