Andrea Stringer

APrf Andrea Stringer

Associate Professor of Medical Sciences

School of Pharmacy and Biomedical Science

College of Health

Available For Media Comment.

A/Prof Andrea Stringer leads the Gut Pathology and Microbiome Science group, with research focussing on the role of vitamin D in the intestine.  Andrea's broad area of research has focussed primarily on gut function, particularly on the role of the gut microbiome in this environment.  She works closely with the Musculoskeletal Biology Research Group investigating links between the gut health and bone outcomes.
Andrea's broad area of expertise is in developing strategies for preventing or treating oral and gastrointestinal damage following cancer treatments (mucositis) to reduce the burden of cancer. She has been involved in multiple pre-clinical investigations with growth factors, and probiotics to investigate their effectiveness in treating cancer treatment-induced mucositis.  Andrea's work has also encompassed identifying the mechanisms underpinning the damage that occurs following cancer treatments, with studies investigating the microbiome, inflammatory cytokines, the mucus barrier, and the enteric nervous system.  Her current work focusses on the role of vitamin D in the intestine, specifically the effects of the microbiome, inflammatory cytokines and the mucus barrier.

My current research focusses on the digestive tract.  The two streams of work are the undesirable effects of cancer therapy (those other than curing the cancer), and the role of the intestine in vitamin D metabolism and bone health and repair. My current projects are:

  • damage to tissue along the entire digestive tract, including the mouth, and the role of endogenous microbiota and inflammatory signalling following cancer therapy
  • intestinal function related to vitamin D synthesis in the intestine and the downstream effects on bone, and the effects of vitamin D on the intestine.

Year Citation
2026 Thianhlun, P. C. K., Sylvester, C. L., Sawyer, R. K., Wardill, H. R., Stringer, A. M., & Anderson, P. H. (2026). Targeted deletion of Cyp24a1 in the intestine reduces mucosal injury and preserves epithelial proliferation after 5-fluorouracil treatment. Journal of Steroid Biochemistry and Molecular Biology, 255(106857), 10 pages.
DOI
2025 Kamath, S., Bryant, R. V., Costello, S. P., Day, A. S., Forbes, B., Haifer, C., . . . Joyce, P. (2025). Translational strategies for oral delivery of faecal microbiota transplantation. Gut, online(12), 1-22.
DOI Scopus7 WoS7 Europe PMC5
2025 Pakuwal, E., Tan, J. L., Page, A. J., Stringer, A. M., Woodman, R. J., & Chinnaratha, M. A. (2025). A systematic review and meta-analysis on the efficacy of fecal microbiome transplantation in patients with severe alcohol-associated hepatitis. European Journal of Gastroenterology and Hepatology, online(11), 1-9.
DOI Scopus1 WoS1
2024 McGuinness, A. J., Stinson, L. F., Snelson, M., Loughman, A., Stringer, A., Hannan, A. J., . . . Wardill, H. R. (2024). From hype to hope: considerations in conducting robust microbiome science. Brain, Behavior, and Immunity, 115, 120-130.
DOI Scopus18 WoS16 Europe PMC12
2024 Stringer, A. M., Hargreaves, B. M., Mendes, R. A., Blijlevens, N. M. A., Bruno, J. S., Joyce, P., . . . Wardill, H. R. (2024). Updated perspectives on the contribution of the microbiome to the pathogenesis of mucositis using the MASCC/ISOO framework. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 32(8), 558-1-558-15.
DOI Scopus11 WoS12 Europe PMC7
2024 Harmon, J., Brown, A., Birbeck, D., Crockett, J., Panadgoo, S., Nawas, A., . . . Costabile, M. (2024). Interdisciplinary reflection by higher education academics using teaching squares: A scoping review. Nurse Education Today, 142(106353), 106353-1-106353-10.
DOI Scopus3 WoS2
2024 Stringer, A. (2024). The systemic outcomes of gastrointestinal mucositis: host-microbe interaction leading to systemic inflammatory responses. Current Opinion in Supportive and Palliative Care, 18(2), 71-72.
DOI Scopus1 WoS1 Europe PMC1
2023 Kamath, S., Stringer, A. M., Prestidge, C. A., & Joyce, P. (2023). Targeting the gut microbiome to control drug pharmacomicrobiomics: the next frontier in oral drug delivery. Expert Opinion on Drug Delivery, 20(10), 1315-1331.
DOI Scopus23 WoS22 Europe PMC19
2023 Munem, F., Thianhlun, P. C. K., Anderson, P. H., & Stringer, A. M. (2023). Vitamin D is a potential treatment for the management of gastrointestinal mucositis. Current Opinion in Supportive and Palliative Care, 17(3), 247-252.
DOI Scopus8 WoS8 Europe PMC6
2022 Araújo, R. S., Oliveira, M. C., Cardoso, V. N., Keefe, D. M. K., & Stringer, A. M. (2022). The effect of free and encapsulated cisplatin into long-circulating and pH-sensitive liposomes on IEC-6 cells during wound healing in the presence of host-microbiota. Journal of Pharmacy and Pharmacology, 74(5), 711-717.
DOI Scopus1 WoS1 Europe PMC2
2022 Malipatlolla, D. K., Devarakonda, S., Patel, P., Sjöberg, F., Rascón, A., Grandér, R., . . . Bull, C. (2022). A fiber-rich diet and radiation-induced injury in the murine intestinal mucosa. International Journal of Molecular Sciences, 23(1, article no. 439), 1-23.
DOI Scopus7 WoS6 Europe PMC5
2022 Alshabrawy, A. K., Cui, Y., Sylvester, C., Yang, D., Petito, E. S., Barratt, K. R., . . . Anderson, P. H. (2022). Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding. Biomolecules, 12(7), 1-14.
DOI Scopus7 WoS8 Europe PMC8
2022 Stringer, A. M. (2022). Effects of coronavirus disease 19 on the gastrointestinal tract and the potential impact on gastrointestinal toxicities during cancer treatment. Current opinion in supportive and palliative care, 16(3), 168-173.
DOI
2022 Ellis, J., Menjak, I. B., Hales, S., Li, M., Blijlevens, N., & Stringer, A. (2022). Editorial introductions. Current Opinion in Supportive and Palliative Care, 16(3), V-VI.
DOI
2020 Dickenson, A. H., Farquhar-Smith, P., Bannister, K., Blijlevens, N., & Stringer, A. (2020). Editorial introductions. Current Opinion in Supportive and Palliative Care, 14(2), V-VI.
DOI
2020 Thorpe, D., Butler, R., Sultani, M., Vanhoecke, B., & Stringer, A. (2020). Irinotecan-induced mucositis is associated with goblet cell dysregulation and neural cell damage in a tumour bearing DA rat model. Pathology and oncology research, 26(2), 955-965.
DOI Scopus19 WoS22 Europe PMC16
2020 Logan, R. M., Al-Azri, A. R., Bossi, P., Stringer, A. M., Joy, J. K., Soga, Y., . . . Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). (2020). Systematic review of growth factors and cytokines for the management of oral mucositis in cancer patients and clinical practice guidelines.. Support Care Cancer, 28(5), 2485-2498.
DOI Scopus62 WoS46 Europe PMC32
2020 Stringer, A. M. (2020). Maintaining anorectal function in patients with rectal cancer using biofeedback training. ANNALS OF TRANSLATIONAL MEDICINE, 8(4), 2 pages.
DOI
2020 Stringer, A. M. (2020). New innovations in therapeutic targets for gastrointestinal toxicity: exploring targets beyond the intestine. Current Opinion in Supportive and Palliative Care, 14(2), 118-119.
DOI
2020 Sylvester, C. L., Anderson, P. H., & Stringer, A. M. (2020). New therapeutic strategies for combatting gastrointestinal toxicity. Current Opinion in Supportive and Palliative Care, 14(2), 142-152.
DOI Scopus5 WoS4 Europe PMC3
2020 Patel, P., Malipatlolla, D. K., Devarakonda, S., Bull, C., Rascon, A., Nyman, M., . . . Sjoberg, F. (2020). Dietary oat bran reduces systemic inflammation in mice subjected to pelvic irradiation. Nutrients, 12(8, article no. 2172), 1-26.
DOI Scopus25 WoS19 Europe PMC13
2020 Elad, S., Cheng, K. K. F., Lalla, R. V., Yarom, N., Hong, C., Logan, R. M., . . . Zur, E. (2020). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer, 126(19), 4423-4431.
DOI Scopus536 WoS506 Europe PMC361
2019 Malipatlolla, D. K., Patel, P., Sjöberg, F., Devarakonda, S., Kalm, M., Angenete, E., . . . Bull, C. (2019). Long-term mucosal injury and repair in a murine model of pelvic radiotherapy. Scientific reports, 9(article no. 13803), 1-10.
DOI Scopus15 WoS15 Europe PMC12
2019 Dickenson, A. H., Farquhar-Smith, P., Bannister, K., Blijlevens, N., & Stringer, A. M. (2019). Editorial introductions. Current Opinion in Supportive and Palliative Care, 13(2), v-vi.
DOI
2019 Wardill, H. R., Tissing, W. J. E., Kissow, H., & Stringer, A. M. (2019). Animal models of mucositis: critical tools for advancing pathobiological understanding and identifying therapeutic targets. Current Opinion in Supportive and Palliative Care, 13(2), 119-133.
DOI Scopus19 WoS18 Europe PMC15
2019 Stringer, A. M., & Blijlevens, N. (2019). Knowledge of gastrointestinal toxicity mechanisms is paving the way for improved assessment and management of patient supportive care. Current opinion in supportive and palliative care, 13(2), 111-113.
DOI
2019 Bowen, J. M., Gibson, R. J., Coller, J. K., Blijlevens, N., Bossi, P., Al-Dasooqi, N., . . . Elad, S. (2019). Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines. Supportive Care in Cancer, 27(10), 4011-4022.
DOI Scopus75 WoS60 Europe PMC46
2019 Bowen, J., Al-Dasooqi, N., Bossi, P., Wardill, H., Van Sebille, Y., Al-Azri, A., . . . Elad, S. (2019). The pathogenesis of mucositis: updated perspectives and emerging targets. Supportive Care in Cancer, 27(10), 4023-4033.
DOI Scopus144 WoS124 Europe PMC100
2019 Hassanshahi, M., Anderson, P. H., Sylvester, C. L., & Stringer, A. M. (2019). Highlight article: Current evidence for vitamin D in intestinal function and disease. Experimental Biology and Medicine, 244(12), 1040-1052.
DOI Scopus13 WoS12 Europe PMC6
2019 Thorpe, D., Sultani, M., & Stringer, A. (2019). Irinotecan induces enterocyte cell death and changes to muc2 and muc4 composition during mucositis in a tumour-bearing DA rat model. Cancer Chemotherapy and Pharmacology, 83(5), 893-904.
DOI Scopus10 WoS10 Europe PMC11
2019 Hedelin, M., Skokic, V., Wilderang, U., Ahlin, R., Bull, C., Sjoberg, F., . . . Steineck, G. (2019). Intake of citrus fruits and vegetables and the intensity of defecation urgency syndrome among gynecological cancer survivors. PLoS ONE, 14(1, article no. e0208115), 1-18.
DOI Scopus6 WoS6 Europe PMC3
2018 Johnson, M. E., Stringer, A., & Bobrovskaya, L. (2018). Rotenone induces gastrointestinal pathology and microbiota alterations in a rat model of Parkinson's disease. NeuroToxicology, 65, 174-185.
DOI Scopus105 WoS88 Europe PMC89
2018 Mahendran, V. J., Stringer, A. M., Semple, S. J., Song, Y., & Garg, S. (2018). Advances in the use of anti-inflammatory agents to manage chemotherapy-induced oral and gastrointestinal mucositis. Current pharmaceutical design, 24(14), 1518-1532.
DOI Scopus25 WoS20 Europe PMC19
2018 Stansborough, R. L., Al-Dasooqi, N., Bateman, E. H., Bowen, J. M., Keefe, D. M. K., Logan, R. M., . . . Gibson, R. J. (2018). Matrix metalloproteinase expression is altered in the small and large intestine following fractionated radiation in vivo. Supportive Care in Cancer, 26(11), 3873-3882.
DOI Scopus8 WoS8 Europe PMC6
2018 Stansborough, R. L., Bateman, E. H., Al-Dasooqi, N., Bowen, J. M., Wignall, A., Keefe, D. M., . . . Gibson, R. J. (2018). Vascular endothelial growth factor (VEGF), transforming growth factor beta (TGFβ), angiostatin, and endostatin are increased in radiotherapy-induced gastrointestinal toxicity. International Journal of Radiation Biology, 94(7), 645-655.
DOI Scopus8 WoS6 Europe PMC6
2017 Mayo, B., Stringer, A., Bowen, J., Bateman, E., & Keefe, D. (2017). Irinotecan-induced mucositis: the interactions and potential role of GLP-2 analogues. Cancer Chemotherapy and Pharmacology, 79(2), 233-249.
DOI Scopus19 WoS17 Europe PMC15
2017 Stansborough, R., Bateman, E., Al-Dasooqi, N., Bowen, J., Keefe, D., Yeoh, A., . . . Gibson, R. (2017). Fractionated abdominal irradiation induces intestinal microvascular changes in an in vivo model of radiotherapy-induced gut toxicity. Supportive Care in Cancer, 25(6), 1973-1983.
DOI Scopus15 WoS14 Europe PMC13
2017 Vanlancker, E., Vanhoecke, B., Stringer, A., & Van de Wiele, T. (2017). 5-Fluorouracil and irinotecan (SN-38) have limited impact on colon microbial functionality and composition in vitro. PeerJ, 2017(11), e4017-1-e4017-20.
DOI Scopus30 WoS26 Europe PMC13
2015 Vanhoecke, B., & Stringer, A. (2015). Host-microbe cross talk in cancer therapy. Current Opinion in Supportive and Palliative Care, 9(2), 174-181.
DOI Scopus11 WoS11 Europe PMC8
2015 Vanhoecke, B., Bateman, E., Mayo, B., Vanlancker, E., Stringer, A., Thorpe, D., & Keefe, D. (2015). Dark Agouti rat model of chemotherapy-induced mucositis: establishment and current state of the art. Experimental Biology and Medicine, 240(6), 725-741.
DOI Scopus30 WoS26 Europe PMC22
2015 Vanhoecke, B., De Ryck, T., Stringer, A., Van de Wiele, T., & Keefe, D. (2015). Microbiota and their role in the pathogenesis of oral mucositis. Oral Diseases, 21(1), 17-30.
DOI Scopus94 WoS78 Europe PMC74
2015 Al-Azri, A. R., Gibson, R. J., Bowen, J. M., Stringer, A. M., Keefe, D. M., & Logan, R. M. (2015). Involvement of matrix metalloproteinases (MMP-3 and MMP-9) in the pathogenesis of irinotecan-induced oral mucositis. Journal of Oral Pathology & Medicine, 44(6), 459-467.
DOI Scopus33 WoS31 Europe PMC24
2015 Stringer, A., & Logan, R. (2015). The role of oral flora in the development of chemotherapy-induced oral mucositis. Journal Of Oral Pathology and Medicine, 44(2), 81-87.
DOI Scopus74 WoS66 Europe PMC53
2014 Bowen, J., Mayo, B., Plews, E., Bateman, E., Wignall, A., Stringer, A., . . . Keefe, D. (2014). Determining the mechanisms of lapatinib-induced diarrhoea using a rat model. Cancer Chemotherapy and Pharmacology, 74(3), 617-627.
DOI Scopus27 WoS22 Europe PMC19
2014 Lalla, R. V., Bowen, J., Barasch, A., Elting, L., Epstein, J., Keefe, D. M., . . . The Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO). (2014). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer, 120(10), 1453-1461.
DOI Scopus925 WoS693 Europe PMC645
2013 Stringer, A. (2013). Interaction between host cells and microbes in chemotherapy-induced mucositis. Nutrients, 5(5), 1488-1499.
DOI Scopus75 WoS70 Europe PMC62
2013 Al-Dasooqi, N., Sonis, S., Bowen, J., Bateman, E., Blijlevens, N., Gibson, R., . . . Lalla, R. (2013). Emerging evidence on the pathobiology of mucositis. Supportive Care in Cancer, 21(11), 3233-3241.
DOI Scopus105 WoS86 Europe PMC83
2013 Bateman, E., Bowen, J., Stringer, A., Mayo, B., Plews, E., Wignall, A., . . . Keefe, D. (2013). Investigation of effect of nutritional drink on chemotherapy-induced mucosal injury and tumor growth in an established animal model. Nutrients, 5(10), 3948-3963.
DOI Scopus9 WoS10 Europe PMC9
2013 Thorpe, D., Stringer, A., & Butler, R. (2013). Chemotherapy-induced mucositis: the role of mucin secretion and regulation, and the enteric nervous system. Neurotoxicology, 38, 101-105.
DOI Scopus31 WoS26 Europe PMC23
2013 Al-Dasooqi, N., Sonis, S., Bowen, J., Bateman, E., Blijlevens, N., Gibson, R., . . . Lalla, R. (2013). Emerging evidence on the pathobiology of mucositis. Supportive Care in Cancer, 21(7), 2075-2083.
DOI Scopus134 WoS115 Europe PMC92
2013 Thorpe, D., Stringer, A., & Gibson, R. (2013). Chemotherapy-induced mucositis: the role of the gastrointestinal microbiome and toll-like receptors. Experimental Biology and Medicine (Maywood), 238(1), 1-6.
DOI Scopus32 WoS28 Europe PMC24
2013 Stringer, A., Al-Dasooqi, N., Bowen, J., Tan, T., Radzuan, M., Logan, R., . . . Gibson, R. (2013). Biomarkers of chemotherapy-induced diarrhoea: a clinical study of intestinal microbiome alterations, inflammation and circulating matrix metalloproteinases. Supportive Care in Cancer, 21(7), 1843-1852.
DOI Scopus120 WoS114 Europe PMC104
2013 Gibson, R., Keefe, D., Lalla, R., Bateman, E., Blijlevens, N., Fijlstra, M., . . . Bowen, J. (2013). Systematic review of agents for the management of gastrointestinal mucositis in cancer patients. Supportive Care in Cancer, 21(1), 313-326.
DOI Scopus181 WoS161 Europe PMC132
2012 Bowen, J., Mayo, B., Plews, E., Bateman, E., Stringer, A., Boyle, F., . . . Keefe, D. (2012). Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea. Cancer Biology & Therapy, 13(13), 1269-1275.
DOI Scopus33 WoS32 Europe PMC33
2012 Sultani, M., Stringer, A., Bowen, J., & Gibson, R. (2012). Anti-inflammatory cytokines: important immunoregulatory factors contributing to chemotherapy-induced gastrointestinal mucositis. Chemotherapy Research and Practice, 2012, 1-11.
DOI Europe PMC67
2011 Keefe, D., Bowen, J., Gibson, R., Tan, T., Okera, M., & Stringer, A. (2011). Noncardiac vascular toxicities of vascular endothelial growth factor inhibitors in advanced cancer: a review. The Oncologist, 16(4), 432-444.
DOI Scopus87 WoS69 Europe PMC51
2011 Al-Dasooqi, N., Bowen, J., Gibson, R., Logan, R., Stringer, A., & Keefe, D. (2011). Selection of housekeeping genes for gene expression studies in a rat model of irinotecan-induced mucositis. Chemotherapy, 57(1), 43-53.
DOI Scopus15 WoS16 Europe PMC14
2011 Al-Dasooqi, N., Bowen, J., Gibson, R., Logan, R., Stringer, A., & Keefe, D. (2011). Irinotecan-induced alterations in intestinal cell kinetics and extracellular matrix component expression in the dark agouti rat. International Journal of Experimental Pathology, 92(5), 357-365.
DOI Scopus36 WoS32 Europe PMC28
2010 Al-Dasooqi, N., Gibson, R., Bowen, J., Logan, R., Stringer, A., & Keefe, D. (2010). Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat. Experimental Biology and Medicine (Maywood), 235(10), 1244-1256.
DOI Scopus59 WoS50 Europe PMC49
2010 Ong, Z., Gibson, R., Bowen, J., Stringer, A., Darby, J., Logan, R., . . . Keefe, D. (2010). Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis. Radiation Oncology, 5(22), 1-8.
DOI Scopus125 WoS114 Europe PMC99
2010 Bowen, J., Tsykin, A., Stringer, A., Logan, R., Gibson, R., & Keefe, D. (2010). Kinetics and regional specificity of irinotecan-induced gene expression in the gastrointestinal tract. Toxicology, 269(1), 1-12.
DOI Scopus11 WoS8 Europe PMC9
2010 Keefe, D., & Stringer, A. (2010). The potential successes and challenges of targeted anticancer therapies. Current opinion in supportive and pallative care, 4(1), 16-18.
DOI Scopus4 Europe PMC4
2010 Al-Dasooqi, N., Gibson, R., Bowen, J., Logan, R., Stringer, A., & Keefe, D. (2010). Matrix metalloproteinases and their inhibitors are altered in a time-course model of irinotecan-induced mucositis. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(s3), A2.
DOI
2009 Stringer, A., Gibson, R., Logan, R., Bowen, J., Yeoh, A., Laurence, J., & Keefe, D. (2009). Irinotecan-induced mucositis is associated with changes in intestinal mucins. Cancer Chemotherapy and Pharmacology, 64(1), 123-132.
DOI Scopus77 WoS73 Europe PMC69
2009 Stringer, A., Gibson, R., Bowen, J., Logan, R., Ashton, K., Yeoh, A., . . . Keefe, D. (2009). Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile. International Journal of Experimental Pathology, 90(5), 489-499.
DOI Scopus136 WoS123 Europe PMC109
2009 Gibson, R., & Stringer, A. (2009). Chemotherapy-induced diarrhoea. Current Opinion in Supportive and Palliative Care, 3(1), 31-35.
DOI Scopus63 Europe PMC44
2009 Stringer, A., Gibson, R., Logan, R., Bowen, J., Yeoh, A., Hamilton, J., & Keefe, D. (2009). Gastrointestinal Microflora and Mucins May Play a Critical Role in the Development of 5-Fluorouracil-Induced Gastrointestinal Mucositis. Experimental Biology and Medicine (Maywood), 234(4), 430-441.
DOI Scopus199 WoS183 Europe PMC153
2009 Stringer, A., Gibson, R., Bowen, J., & Keefe, D. (2009). Chemotherapy-induced modifications to gastrointestinal microflora: Evidence and implications of change. Current Drug Metabolism, 10(1), 79-83.
DOI Scopus98 WoS86 Europe PMC76
2009 Logan, R., Stringer, A., Bowen, J., Gibson, R., Sonis, S., & Keefe, D. (2009). Is the pathobiology of chemotherapy-induced alimentary tract mucositis inXuenced by the type of mucotoxic drug administered?. Cancer Chemotherapy and Pharmacology, 63(2), 239-251.
DOI Scopus144 WoS132 Europe PMC113
2009 Stringer, A. M., Gibson, R. J., Bowen, J. M., Logan, R. M., Al-Dasooqi, N., & Keefe, D. M. K. (2009). The importance of the gut microbiome in gastrointestinal mucositis. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24, A237.
2008 Logan, R., Gibson, R., Bowen, J., Stringer, A., Sonis, S., & Keefe, D. (2008). Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis. Cancer Chemotherapy and Pharmacology, 62(1), 33-41.
DOI Scopus164 WoS150 Europe PMC145
2008 Stringer, A., Gibson, R., Logan, R., Bowen, J., Yeoh, A., & Keefe, D. (2008). Faecal microflora and β-glucuronidase expression are altered in an irinotecan-induced diarrhea model in rats. Cancer Biology & Therapy, 7(12), 1919-1925.
DOI Scopus178 WoS157 Europe PMC143
2008 Logan, R., Stringer, A., Bowen, J., Gibson, R., Sonis, S., & Keefe, D. (2008). Serum levels of NF kappa B and pro-inflammatory cytokines following administration of mucotoxic drugs. Cancer Biology & Therapy, 7(7), 1139-1145.
DOI Scopus165 WoS142 Europe PMC125
2007 Bowen, J., Gibson, R., Stringer, A., Chan, T., Prabowo, A., Cummins, A., & Keefe, D. (2007). Role of p53 in irinotecan-induced intestinal cell death and mucosal damage. Anti-Cancer Drugs, 18(2), 197-210.
DOI Scopus24 WoS21 Europe PMC21
2007 Stringer, A., Gibson, R., Logan, R., Bowen, J., Yeoh, A., Burns, J., & Keefe, D. (2007). Chemotherapy-induced diarrhea is associated with changes in the luminal environment in the DA rat. Experimental Biology and Medicine (Maywood), 232(1), 96-106.
Scopus98 WoS83 Europe PMC55
2007 Bowen, J., Stringer, A., Gibson, R., Yeoh, A., Hannam, S., & Keefe, D. (2007). VSL#3 probiotic treatment reduces chemotherapy-induced diarrhoea and weight loss. Cancer Biology & Therapy, 6(9), 1449-1454.
DOI Scopus189 WoS169 Europe PMC138
2007 Stringer, A., Gibson, R., Bowen, J., Logan, R., Yeoh, A., & Keefe, D. (2007). Chemotherapy-induced mucositis: The role of gastrointestinal microflora and mucins in the luminal environment. The Journal of Supportive Oncology, 5(6), 259-267.
Scopus72 Europe PMC48
2007 Logan, R., Stringer, A., Bowen, J., Yeoh, A., Gibson, R., Sonis, S., & Keefe, D. (2007). The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: Pathobiology, animal models and cytotoxic drugs. Cancer Treatment Reviews, 33(5), 448-460.
DOI Scopus246 WoS223 Europe PMC193
2007 Bowen, J., Gibson, R., Tsykin, A., Stringer, A., Logan, R., & Keefe, D. (2007). Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy. International Journal of Cancer, 121(8), 1847-1856.
DOI Scopus41 WoS39 Europe PMC36
2007 Yeoh, A., Gibson, R., Yeoh, E., Bowen, J., Stringer, A., Giam, K., & Keefe, D. (2007). A novel animal model to investigate fractionated radiotherapy-induced alimentary mucositis: the role of apoptosis p53 nuclear factor-kappa B COX-1 and COX-2. Molecular Cancer Therapeutics, 6(8), 2319-2327.
DOI Scopus53 WoS46 Europe PMC44
2007 Gibson, R., Stringer, A., Bowen, J., Logan, R., Yeoh, A., Burns, J., . . . Keefe, D. (2007). Velafermin improves gastrointestinal mucositis following irinotecan treatment in tumor-bearing DA rats. Cancer Biology & Therapy, 6(4), 541-547.
DOI Scopus16 WoS14 Europe PMC10
2007 Stringer, A. M., Gibson, R., Logan, R., Bowen, J., Yeoh, A., Burns, J., & Keefe, D. (2007). Chemotherapy-induced diarrhea is associated with changes in the luminal environment in the DA rat. Experimental Biology and Medicine.
2006 Yeoh, A., Gibson, R., Yeoh, E., Bowen, J., Stringer, A., Giam, K., . . . Keefe, D. (2006). Radiation therapy-induced mucositis: Relationships between fractionated radiation, NF-kappa B, COX-1, and COX-2. Cancer Treatment Reviews, 32(8), 645-651.
DOI Scopus45 WoS40 Europe PMC32
2006 von Bultzingslowen, I., Brennan, M., Spijkervet, F., Logan, R., Stringer, A., Raber-Durlacher, J., & Keefe, D. (2006). Growth factors and cytokines in the prevention and treatment of oral and gastrointestinal mucositis. Supportive Care in Cancer, 14(6), 519-527.
DOI Scopus62 WoS52 Europe PMC44
2006 Stringer, A. M., Gibson, R. J., Logan, R. M., Bowen, J. M., Yeoh, A. S. J., & Keefe, D. M. K. (2006). Chemotherapy-induced changes in mucin secretion and composition. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21, A266.
WoS2
2006 Yeoh, A., Gibson, R., Yeoh, E., Bowen, J., Stringer, A., Giam, K., & Keefe, D. (2006). A novel animal model to investigate radiation-induced mucositis: a qualitative assessment of mucosal injury resulting from fractionated radiotherapy. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21, A260.
1999 Gordon, A. N., Hancock, K. C., Matthews, C. M., Stringer, A., Boston, J., & Nemunaitis, J. (1999). A phase I/II dose escalation study of carboplatin in the treatment of newly diagnosed patients with advanced ovarian cancer receiving paclitaxel. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 22(6), 601-605.
DOI WoS5 Europe PMC5

Year Citation
2020 Sylvester, C. L., Anderson, P. H., & Stringer, A. M. (2020). Therapeutic inhibition vs. intestinal deletion of CYP24A1 and its effects on chemotherapy-induced gastrointestinal mucositis. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 16 (pp. 111). WILEY.
2020 Sylvester, C., Anderson, P., & Stringer, A. (2020). Inhibition of vitamin D catabolism and its effects on chemotherapy-induced gastrointestinal mucositis. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 32 (pp. 2 pages). WILEY.
2019 Sylvester, C. L., Anderson, P. H., & Stringer, A. M. (2019). Inhibition of vitamin D catabolism and its effects on chemotherapy-induced gastrointestinal mucositis. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 15 (pp. 62). WILEY.
2018 Wardill, H., Secombe, K., Gibson, R., Stringer, A., Al-Dasooqi, N., Mayo, B., & Bowen, J. (2018). Pre-treatment blautia abundance regulates chemo-toxicity in colorectal cancer patients: A pilot study. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 30 (pp. 1 page). WILEY.
2018 Secombe, K., Bowen, J., Coller, J., Gibson, R., Stringer, A., Al-Dasooqi, N., . . . Wardill, H. R. (2018). Pre-treatment Blautia abundance regulates chemotherapy-induced gastrointestinal toxicity risk: a pilot study. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 14 (pp. 59). WILEY.
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2017 Mullen, C. M., Halkos, M. E., Anderson, A., Carssow, K., Cook, R., Bove, J. M., & Stringer, A. M. (2017). The Relationship of Coronary Artery Disease to Neuropsychological Functioning. In CLINICAL NEUROPSYCHOLOGIST Vol. 31 (pp. 725). TAYLOR & FRANCIS INC.
2017 Mullen, C. M., Halkos, M. E., Anderson, A., Carssow, K., Cook, R., Bove, J. M., & Stringer, A. M. (2017). The Relationship of Coronary Artery Disease to Neuropsychological Functioning. In CLINICAL NEUROPSYCHOLOGIST Vol. 31 (pp. 728). TAYLOR & FRANCIS INC.
2016 Ikanga, J., Penna, S., Gravano, J., Mccartney, R., & Stringer, A. (2016). Posterior cortical atrophy: does early age onset lead to more aggressive presentation? A case series. In CLINICAL NEUROPSYCHOLOGIST Vol. 30 (pp. 381). TAYLOR & FRANCIS INC.
2015 Vanhoecke, B., Mayo, B., Wignall, A., Ziegler, V., Stringer, A., Bateman, E., . . . Keefe, D. (2015). Irinotecan induces DNA damage in the oral cavitiy of the Dark Agouti rats without visual signs of lesions. In Supportive Care in Cancer Vol. 23 (pp. S115). Copenhagen, Denmark: Springer Verlag (Germany).
DOI
2015 Mayo, B., Stringer, A., Lucchesi, C., Bowen, J., Bateman, E., Wignall, A., . . . Keefe, D. (2015). Microbial alterations and toll-like receptor expression play a role in the improvement of irinotecan-induced mucositis after treatment with the new selective GLP-2 receptor agonist, Elsiglutide. In Supportive Care in Cancer Vol. 23 (pp. S111). Copenhagen, Denmark: Springer Verlag (Germany).
DOI
2013 Al-Azri, A. S., Logan, R., Gibson, R., Keefe, D., stringer, A., & Bowen, J. (2013). The role of matrix metalloproteinases and tissue inhibitors of metalloproteinase in irinotecan induced-chemotherapy. In Supportive Care in Cancer. Berlin Genrmany: Springer Verlag (Germany).
2011 Al-Dasooqi, N., Mayo, B., Bowen, J., Stringer, A., Gibson, R., & Keefe, D. (2011). Pilot study of biomarkers of chemotherapy-induced Gastrointestinal Toxicity. In Proceedings of the COSA Annual Scientific Meeting Vol. 7 (pp. 1). United Kingdom: Blackwell Publishing Ltd..
DOI
2011 Stringer, A., Gibson, R., Yeoh, A., Bowen, J., & Keefe, D. (2011). Chemotherapy-induced diarrhoea is associated with a modified intestinal microbiome and intestinal inflammation. In Abstracts of the 2011 International MASCC/ISOO Symposium Vol. 19 (pp. 153). 175 Fifth Ave New York NY 10010: Springer-Verlag.
DOI
2011 Mayo, B., Bowen, J., Stringer, A., Bateman, E., Plews, E., Darby, J., . . . Keefe, D. (2011). The effect of ErbB inhibition on chemotherapy-induced intestinal damage. In Abstracts of the 2011 International MASCC/ISOO Symposium Vol. 19 (pp. 0 pages). 175 Fifth Ave New York NY 10010: Springer-Verlag.
DOI
2010 Al-Dasooqi, N., Bowen, J., Gibson, R., Logan, R., Stringer, A., & Keefe, D. (2010). Irinotecan-induced mucositis encompasses changes in intestinal and colonic cell kinetics and this is associated with altered extracellular matrix component expression. In Abstracts of the 2010 International MASCC/ISOO Symposium Vol. 25 (pp. 0 pages). Vancouver, Canada: Springer-Verlag.
DOI
2010 Al-Dasooqi, N., Gibson, R., Bowen, J., Logan, R., Stringer, A., & Keefe, D. (2010). Matrix metalloproteinases play a pivotal role in the development of alimentary tract mucositis. In Sydney Cancer Conference (pp. 0 pages). The University of Sydney, NSW, Australia.
2009 Stringer, A., Gibson, R., Yeoh, A., Bowen, J., Logan, R., & Keefe, D. (2009). CHEMOTHERAPY-INDUCED DIARRHOEA IS ASSOCIATED WITH A MODIFIED MICROBIOME IN GI CANCER PATIENTS. In ANNALS OF ONCOLOGY Vol. 20 (pp. 73). Barcelona, SPAIN: OXFORD UNIV PRESS.
2007 Logan, R., Gibson, R., Stringer, A., Bowen, J., Sonis, S., & Keefe, D. (2007). Serum levels of nuclear factor-κB and tumour necrosis factor following irinotecan administration in the Dark Agouti rat. In ORAL ONCOLOGY (pp. 211). Amsterdam, NETHERLANDS: ELSEVIER SCIENCE BV.
2007 Logan, R., Gibson, R., Stringer, A., Bowen, J., Sonis, S., & Keefe, D. (2007). Nuclear factor-KB and cyclooxygenase-2 expression in the oral mucosa following cancer chemotherapy. In ORAL ONCOLOGY (pp. 171). Amsterdam, NETHERLANDS: ELSEVIER SCIENCE BV.

Year Citation
2014 Stringer, A., McInnes, H., Mayo, B., Logan, R., & Vanhoecke, B. (2014). The effect of oral microbes on the proliferation, healing, and immune response of intestinal epithelial cells, IEC, treated with SN-, metabolite of irinotecan. Poster session presented at the meeting of Asia-Pacific Journal Of Clinical Oncology. Melbourne, Vic.: Wiley.
DOI
2014 Mayo, B., Bateman, E., Stringer, A., Plews, E., Wignall, A., Wozniak, B., . . . Keefe, D. (2014). The new selective glp-2 receptor agonist, elsiglutide, improves irinotecan-induced diarrhoea and mucositis in the rat. Poster session presented at the meeting of Asia-Pacific Journal Of Clinical Oncology. Melbourne, Vic.: Wiley.
DOI WoS1
2014 Mayo, B., Stringer, A., Bateman, E., Bowen, J., Wignall, A., Wozniak, B., . . . Keefe, D. (2014). Apoptosis, proliferation and inflammation are improved after treatment with the new selective glp-2 receptor agonist, elsiglutide, in a rat model of irinotecan-induced mucositis. Poster session presented at the meeting of Asia-Pacific Journal Of Clinical Oncology. Melbourne, Vic.: Wiley.
DOI
2014 Mayo, B., Bateman, E., Stringer, A., Plews, E., Wignall, A., Wozniak, B., . . . Keefe, D. (2014). The new selective GLP-2 receptor agonist, Elsiglutide, improved irinotecan-induced diarrhoea and mucositis in the rat. Poster session presented at the meeting of Supportive Care in Cancer. Miami, USA: Springer Verlag (Germany).
2014 Mayo, B., Stringer, A., Bateman, E., Bowen, J., Pietra, C., Cantoreggi, S., & Keefe, D. (2014). Apoptosis, proliferation and inflammation are improved after treatment with the new selective GLP-2 receptor agonist, Elsiglutide, in a rat model of irinotecan-induced mucositis. Poster session presented at the meeting of Supportive Care in Cancer. Miami, USA: Springer Verlag (Germany).
2014 Thorpe, D., Stringer, A., & Butler, R. (2014). GASTROINTESTINAL MUCOSITIS IS ASSOCIATED WITH MUC 2 AND 4 EXPRESSION, AND EXOCYTOSIS OF MUCIN STORES. Poster session presented at the meeting of ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY-BLACKWELL.
2013 Mayo, B., Bateman, E., Stringer, A., Plews, E., Pishas, K., Pietra, C., . . . Keefe, D. (2013). The effect of the new selective GLP-2 agonist, Elsiglutide, on irinotecan-induced diarrhoea and mucositis in the rat.. Poster session presented at the meeting of Supportive Care in Cancer. Berlin, Germany: Springer Verlag (Germany).
DOI
2013 Radzuan, M., Bateman, E., Bowen, J., Keefe, D., & Stringer, A. (2013). Intestinal Lactobacillus spp. increase following radiotherapy in rats: an unusual finding. Poster session presented at the meeting of Supportive Care in Cancer. Berlin, Germany: Springer Verlag (Germany).
2013 Mayo, B., Bateman, E., Stringer, A., Plews, E., Pishas, K., Pietra, C., . . . Keefe, D. (2013). The effect of the new selective GLP-2 agonist, elsiglutide, on irinotecan-induced diarrhoea and mucositis in the rat. Poster session presented at the meeting of Asia-Pacific Journal of Clinical Oncology. Adelaide Convention Centre, Adelaide, South Australia: Wiley Publishing Asia.
DOI
2011 Bateman, E., Bowen, J., Mayo, B., Plews, E., Darby, J., Stringer, A., . . . Keefe, D. (2011). Further characterisation of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor-induced diarrhoea. Poster session presented at the meeting of Abstracts of the 2011 International MASCC/ISOO Symposium, as published in Supportive Care in Cancer. Athens: Springer-Verlag.
DOI
2009 Stringer, A. M., Gibson, R. J., Bowen, J. M., Logan, R. M., Al-Dasooqi, N., & Keefe, D. M. K. (2009). Chemotherapy-induced diarrhoea is associated with a modified microbiome in cancer patients. Poster session presented at the meeting of Abstracts of the Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, as published in Journal of Gastroenterology and Hepatology. Sydney, N.S.W.: Wiley-Blackwell.
DOI

Year Citation
- Pakuwal, E., Hargreaves, B., Moradi, M., Page, A. J., Chinnaratha, M. A., & Stringer, A. M. (n.d.). The Efficacy of Microbiome-Targeted Therapy in Modulating Gut Health in Alcohol-Induced Liver Injury: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols.
DOI

Year Citation
2024 Thorpe, D., Wang, W., Milne, R., & Stringer, A. (2024). Different liposomal formulations of 5-Fluorouracil result in variations to gastrointestinal toxicities.
DOI

Date Role Research Topic Program Degree Type Student Load Student Name
2023 External Supervisor Qualitative gut microbiome assessment and the role of faecal microbiota transplantation (FMT) in Severe alcoholic hepatitis (sAH) Doctor of Philosophy Doctorate Full Time Miss Evance Pakuwal

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