
Dr Alexandra Mc Carron
NHMRC Grant-Funded Researcher A
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
I am a postdoctoral researcher with the Cystic Fibrosis Airway Research Group (CFARG), based in the Department of Respiratory Medicine at the Women's and Children's Hospital.
My research
My research is in the area of airway gene therapy, a therapeutic approach that has potential to treat or prevent cystic fibrosis lung disease by correcting the underlying genetic defect. My work includes the production of lentiviral gene vectors, characterising and employing cystic fibrosis animal models for trialing of airway gene therapy, and investigating novel methods for enhancing the efficacy of airway gene transfer.
Student projects
I have projects available for Summer Research Scholarship students, Bachelor of Health and Medical Sciences (BHMS) Third Year Research Placement students, and Honours students. The skills developed during these projects can include: rodent handling, airway gene delivery techniques, tissue collection, histology, immunohistochemistry, cell culture, gene vector production, data collection, analysis and interpretation.
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Education
Date Institution name Country Title 2021 The University of Adelaide Australia PhD in Medicine 2015 The University of Adelaide Australia Bachelor of Health Science (Honours) 2014 The University of Adelaide Australia Bachelor of Science (Animal Science)
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Journals
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Conference Papers
Year Citation 2019 Morgan, K. S., Gradl, R., Dierolf, M., Jud, C., Günther, B., Werdiger, F., . . . Donnelley, M. (2019). In vivo x-ray imaging of the respiratory system using synchrotron sources and a compact light source. In B. Müller, & G. Wang (Eds.), Developments in X-Ray Tomography XII Vol. 11113 (pp. 111130G-1-111130G-12). online: Society of Photo-optical Instrumentation Engineers.
Scopus12019 Li, J., Quirk, B. C., Delhove, J., Kirk, R., Mc Carron, A., Cmielewski, P., . . . McLaughlin, R. A. (2019). Imaging genetically-modified cells with a miniaturised multimodal optical coherence tomography + fluorescence probem. In Proceedings of the 2019 IEEE Photonics Conference (IPC) (pp. 1-2). Piscataway, NJ: IEEE.
2019 McCarron, A., Donnelley, M., Cmielewski, P., McIntyre, C., & Parsons, D. (2019). Transient Lentiviral Vector Production Using a Packed-Bed Bioreactor System. In MOLECULAR THERAPY Vol. 27 (pp. 209). Washington, DC: CELL PRESS.
2023- 2024 Channel 7 Children's Research Foundation "Does the presence of lung infection impact the efficacy of cystic fibrosis airway gene therapy?", $40,060 (Chief investigator)
2020 - 2021 Women's and Children's Hospital Foundation "Airway gene correction in neonatal cystic fibrosis rats", $100,000 (Chief investigator)
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Co-Supervisor Understanding and improving gene vector targeting with lentiviral magnetic nanoparticles Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Part Time Ms Madison Michelle Davis 2021 Co-Supervisor Improving the effectiveness of airway lentiviral gene therapy for cystic fibrosis Doctor of Philosophy Doctorate Full Time Mrs Nikki Reyne
Connect With Me
External Profiles