Nikki Reyne

Nikki Reyne

Research Assistant

Adelaide Medical School

Faculty of Health and Medical Sciences

I am a PhD student working with the Adelaide Cystic Fibrosis Airway Research Group based in the Women's and Children's Hospital.

My research goals have focused around reducing or preventing CF lung disease using genetic therapies. In 2019, I undertook an honours project where I was awarded First Class Honours. This project successfully showed for the first time CFTR correction in vivo in the nasal airway epithelium of CF rat models, after the delivery of lentiviral vector.

My current work involves using XV imaging to study the lung function and structure of animal disease models in high detail. I have used this technology to identify lung function differences in CF rats, B-ENaC mice, and obstructive lung models. I also have an interest in Pseudomonas aeruginosa respiratory infections in CF and has developed and characterised a CF rat pseudomonas model.

I am responsible for breeding and managing the only two CF rat models in the Southern Hemisphere.

I am a PhD candidate at the University of Adelaide (submitting August 2024) and am based in Respiratory Medicine at the Women’s and Children’s Hospital.

  • Education
    Date Institution name Country Title
    The University of Adelaide Australia Bachelor of Science - Animal Science
    The University of Adelaide Australia Bachelor of Science (Honours)

2024     N. Reyne, R, Smith, M. Donnelley and D. Parsons. Robinson Research Institute Step Funding. “X-ray velocimetry lung function imaging in the β-ENaC mouse model of cystic fibrosis.” $14,979.

2024     N. Rout-Pitt, A. McCarron, N. Reyne, D. Parsons. M. Donnelley. Cystic Fibrosis Foundation, "Unravelling the Role of Epithelial-Mesenchymal Transition (EMT) in Cystic Fibrosis Lung Disease: Insights, Challenges, and Therapeutic Prospects", $175,000.

2023     E. Schneider-Futschik, J. Bourke, D. Parsons, H. Chinnery. J. Taylor-Cousar, P. Middleton, A. McCarron and N. Reyne. Cystic Fibrosis Foundation “Delaying the onset of cystic fibrosis pathologies” $282,000

2023     A. McCarron, N. Reyne, P. Cmielewski, M. Donnelley, D. Parsons. Channel 7 Children’s Research Foundation. “Does the presence of lung infection impact the efficacy of cystic fibrosis airway gene therapy?” $40,060.

  • Position: Research Assistant
  • Phone: 83135340
  • Email: nikki.reyne@adelaide.edu.au
  • Campus: Women�s and Children�s Hospital
  • Building: Gilbert, floor 6
  • Org Unit: Adelaide Medical School
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