Nikki Reyne

Nikki Reyne

Higher Degree by Research Candidate

PhD Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences

I am a PhD student working with the Adelaide Cystic Fibrosis Airway Research Group based in the Women's and Children's Hospital.

I completed a Bachelor of Animal Science at The University of Adelaide and spent 8 years working in animal
laboratories. In 2018 I joined Cystic Fibrosis Airway Research Group as a Research Assistant. My role primary
involves overseeing the CF rat colony and assisting with rat procedures. In 2019, I undertook an honours project where
I was awarded First Class Honours. This project successfully showed for the first time CFTR correction in vivo in the
nasal airway epithelium of CF rat models, after the delivery of lentiviral vector. I have since enrolled into a PhD project in 2021, continuing to improve the effectiveness of airway lentiviral gene therapy for cystic fibrosis.

  • Education

    Date Institution name Country Title
    The University of Adelaide Australia Bachelor of Science - Animal Science
    The University of Adelaide Australia Bachelor of Science (Honours)
  • Journals

    Year Citation
    2021 Reyne, N., Cmielewski, P., McCarron, A., Delhove, J., Parsons, D., & Donnelley, M. (2021). Single-dose lentiviral mediated gene therapy recovers CFTR function in cystic fibrosis knockout rats. Frontiers in Pharmacology, 12, 682299-1-682299-8.
    DOI Scopus1 WoS1 Europe PMC1
    2020 McCarron, A., Cmielewski, P., Reyne, N., McIntyre, C., Finnie, J., Craig, F., . . . Donnelley, M. (2020). Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing. The American Journal of Pathology, 190(5), 977-993.
    DOI Scopus10 WoS10 Europe PMC8
  • Position: PhD Candidate
  • Phone: 83135340
  • Email:
  • Campus: Women�s and Children�s Hospital
  • Building: Gilbert, floor 6
  • Room: G6-026
  • Org Unit: Adelaide Medical School

Connect With Me
External Profiles