Janna Morrison

Prof Janna Morrison

Research Professor of Physiology

School of Pharmacy and Biomedical Science

College of Health

Available For Media Comment.


Professor Janna Morrison is Head of the Early Origins of Adult Health Research Group at the University of South Australia. Prof Morrison has been funded as a research fellow by the Heart Foundation (2004-13) and the NHMRC (2014-17). She currently holds an ARC Future Fellowship (2018-2021). She is the inaugral Director of Health and Biomedical Innovation at UniSA.
After completing her PhD at the University of British Columbia, Janna held postdoctoral positions at University of Toronto and the University of Adelaide before joining UniSA in 2006. Among her numerous awards and achievements, Janna received a South Australian Tall Poppy Science Award (2006) in recognition of her work examining the link between low birth weight and heart disease in adulthood. Prof Janna Morrison has authored >170 peer reviewed publications, has been cited over 6,850 times and has an h-Index of 35 (Scopus).
Her current research focusses on how the fetal cardiovascular system responds to changes in nutrient supply before conception and during pregnancy. She uses Magnetic Resonance Imaging (MRI) to measure blood flow and oxygen saturation in the fetus and then links this data to the molecular signalling pathways that control cardiac growth. She also studies how the fetus regulates its blood pressure to maintain adequate perfusion to organs to promote optimal growth and development. More recently, she has looked at the other end of the spectrum, the effects of maternal obesity on heart development.
Prof Morrison shares her passion for understanding life before birth with students through teaching second and third year students in Physiology (BIOL 2035) as well as supervising research students. She has supervised 10 HDR students to completion with another 6 currently in the team. She enjoys introducing undergraduate and Honours students to the research environment. Her team provides a positive and supportive environment for answering a range of questions about how babies develop before birth and how this may influence their lifelong health.

My vision is for fewer Australians to die from heart disease and my research examines the molecular and cellular mechanisms linking poor prenatal growth with increased risk of cardiovascular disease in adult life.

Babies born small have hearts with fewer but larger heart muscle cells (hypertrophy). World-wide epidemiological studies show that small babies (<2.5kg) are at 50% higher risk for heart disease as adults, including hypertension, stroke and heart attack. My SRF will use well- established and clinically-relevant large animal models of pregnancy and heart disease to: (A) enable development and testing of new MRI- based in utero diagnosis to identify small fetuses at-risk of hypertrophic heart development, improving on current ultrasound methods that miss some small babies; and then, test two molecular interventions to halt or reverse unhealthy heart development in utero, specifically: (B) an epigenetic modifying agent, provided orally to the mother or intracardiac to the fetus, or (C) microRNAs, administered to the fetal heart. Both interventions ultimately aim to increase the number of cells in the developing heart and ensure their size is physiologically correct.

Year Citation
2025 Roff, A. J., Robinson, J. L., Hammond, S. J., Bednarz, J., Tai, A., Clifton, V. L., . . . Gatford, K. L. (2025). Maternal asthma during pregnancy and risks of allergy and asthma in progeny: A systematic review and meta-analysis. BJOG: an International Journal of Obstetrics and Gynaecology, 132(8), 1045-1055.
DOI Scopus3 WoS3 Europe PMC4
2025 Amanollahi, R., Holman, S. L., Meakin, A. S., Padhee, M., Botting-Lawford, K. J., Zhang, S., . . . Morrison, J. L. (2025). In Vitro Embryo Culture Impacts Heart Mitochondria in Male Adolescent Sheep. Journal of Developmental Biology, 13(2), 17-1-17-20.
DOI
2025 Meakin, A. S., Lock, M. C., Holman, S. L., Robinson, J. L., Clifton, V. L., Roberts, C. T., . . . Morrison, J. L. (2025). Sex-specific effects of betamethasone on glucocorticoid and apoptotic signalling pathways in the sheep placenta. Journal of Physiology, 603(17), 4867-4886.
DOI
2025 Amanollahi, R., Meakin, A. S., Holman, S. L., Clifton, V. L., Thornburg, K. L., Wiese, M. D., . . . Morrison, J. L. (2025). Antenatal betamethasone impairs markers of cardiac development and function in near-term lambs. Experimental Physiology, online, EP093025-1-EP093025-20.
DOI
2025 Meakin, A. S., Nathanielsz, P. W., Li, C., Clifton, V. L., Huber, H. F., Wiese, M. D., & Morrison, J. L. (2025). Sexually dimorphic responses in androgen metabolism and signalling in the non-human primate placenta to moderate maternal undernutrition. Biology Of Sex Differences, 16(1, article no. 93), 1-14.
DOI
2025 Hammond, S. J., Roff, A. J., Robinson, J. L., Darby, J. R. T., Meakin, A. S., Clifton, V. L., . . . Gatford, K. L. (2025). In utero exposure to experimental maternal asthma alters fetal airway development in sheep. Experimental Physiology, 110(6), 899-907.
DOI Scopus2 WoS2 Europe PMC3
2025 Roff, A. J., Davies, A. N., Clifton, V. L., Stark, M. J., Tai, A., Robinson, J. L., . . . Gatford, K. L. (2025). Pregnancy does not affect progression of mild experimental asthma in sheep. The Journal of Physiology, 603(5), 1241-1261.
DOI Scopus2 WoS2 Europe PMC2
2025 Amanollahi, R., Holman, S. L., Bertossa, M. R., Meakin, A. S., Clifton, V. L., Thornburg, K. L., . . . Morrison, J. L. (2025). Elevated cortisol concentration in preterm sheep fetuses impacts heart development. Experimental Physiology, online(12), 1-20.
DOI Scopus2 WoS2 Europe PMC1
2025 Flouri, D., Darby, J. R. T., Holman, S. L., Williams, G., Vavourakis, V., David, A. L., . . . Melbourne, A. (2025). Feasibility of multimodal magnetic resonance imaging to assess maternal hyperoxygenation in sheep pregnancy. The Journal of Physiology, 603(5), 1029-1044.
DOI
2025 Mcgillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Morrison, J. L. (2025). Antenatal Vitamin C differentially affects lung development in normally grown and growth restricted sheep. Pediatric Research, online(1), 1-12.
DOI
2025 Bennett, M. G. A., Meakin, A. S., Botting-Lawford, K. J., Niu, Y., Ford, S. G., Murphy, M. P., . . . Morrison, J. L. (2025). Maternal MitoQ Treatment Is Protective Against Programmed Alterations in CYP Activity Due to Antenatal Dexamethasone. Pharmaceutics, 17(3), 16 pages.
DOI Scopus2 WoS2
2025 Amanollahi, R., Holman, S. L., Bertossa, M. R., Meakin, A. S., Thornburg, K. L., McMillen, I. C., . . . Morrison, J. L. (2025). Ontogeny of Fetal Cardiometabolic Pathways: The Potential Role of Cortisol and Thyroid Hormones in Driving the Transition from Preterm to Near-Term Heart Development in Sheep. Journal of Cardiovascular Development and Disease, 12(2), 21 pages.
DOI Scopus6 WoS6 Europe PMC6
2025 Cho, S. K. S., Darby, J. R. T., Williams, G. K., Holman, S. L., Rai, A., Van Amerom, J. F. P., . . . Seed, M. (2025). Post-myocardial infarction remodeling and hyperkinetic remote myocardium in sheep measured by cardiac MRI feature tracking. Journal of Magnetic Resonance Imaging, 61(3), 1323-1335.
DOI Scopus2 Europe PMC2
2024 Bertossa, M. R., Darby, J. R. T., Holman, S. L., Meakin, A. S., Li, C., Huber, H. F., . . . Morrison, J. L. (2024). Maternal high fat–high energy diet alters metabolic factors in the non-human primate fetal heart. Journal of Physiology, 602(17), 4251-4269.
DOI Scopus5 WoS4 Europe PMC3
2024 Zhang, S., Lock, M. C., Tie, M., McMillen, I. C., Botting, K. J., & Morrison, J. L. (2024). Cardiac programming in the placentally restricted sheep fetus in early gestation. Journal of Physiology, 602(15), 3815-3832.
DOI Scopus5 WoS5 Europe PMC4
2024 Robinson, J. L., Roff, A. J., Hammond, S. J., Darby, J. R. T., Meakin, A. S., Holman, S. L., . . . Gatford, K. L. (2024). Betamethasone improved near-term neonatal lamb lung maturation in experimental maternal asthma. Experimental Physiology, 109(11), 1967-1979.
DOI Scopus4 WoS4 Europe PMC6
2024 Sadiku, E., Sun, L., Macgowan, C. K., Seed, M., & Morrison, J. L. (2024). Advanced magnetic resonance imaging in human placenta: insights into fetal growth restriction and congenital heart disease. Frontiers in Cardiovascular Medicine, 11(1426593), 1-14.
DOI Scopus4 Europe PMC2
2024 Kühle, H., Cho, S. K. S., Charest Pekeski, A. J., Chow, J. S. M., Lee, F. T., Aujla, T., . . . Haller, C. (2024). Echocardiographic assessment of cardiovascular physiology of preterm miniature piglets supported with a pumped artificial placenta system. Prenatal Diagnosis, 44(6-7), 888-898.
DOI Scopus1 Europe PMC1
2024 Holmes, H., Saini, B. S., Moir, O. J., Darby, J. R. T., Morrison, J. L., Sun, L., & Seed, M. (2024). Pulmonary vascular regulation in the fetal and transitional lung. Clinics in Perinatology, 51(1), 1-19.
DOI Scopus1
2024 Cho, S. K. S., Darby, J. R. T., Saini, B. S., Holman, S. L., Lock, M. C., Perumal, S. R., . . . Morrison, J. L. (2024). Late-gestation maternal undernutrition induces circulatory redistribution while preserving uteroplacental function independent of fetal glycaemic state. Journal of Physiology, 602(24), 7065-7083.
DOI Scopus3 WoS2 Europe PMC3
2024 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Bertossa, M. R., Holman, S. L., . . . Giussani, D. A. (2024). Chronic fetal hypoxia and antenatal Vitamin C exposure differentially regulate molecular signalling in the lung of female lambs in early adulthood. Frontiers in Physiology, 15, 14 pages.
DOI Scopus2 WoS1 Europe PMC1
2024 Dimasi, C. G., Darby, J. R. T., Holman, S. L., Quinn, M., Meakin, A. S., Seed, M., . . . Morrison, J. L. (2024). Cardiac growth patterns and metabolism before and after birth in swine: Role of miR in proliferation, hypertrophy and metabolism. Journal of Molecular and Cellular Cardiology Plus, 9(100084), 14 pages.
DOI Scopus4 WoS4 Europe PMC4
2024 Dimasi, C. G., Darby, J. R. T., Cho, S. K. S., Saini, B. S., Holman, S. L., Meakin, A. S., . . . Morrison, J. L. (2024). Reduced in utero substrate supply decreases mitochondrial abundance and alters the expression of metabolic signalling molecules in the fetal sheep heart. Journal of Physiology, 602(21), 5901-5922.
DOI Scopus16 WoS17 Europe PMC15
2024 Darby, J. R. T., Saini, B. S., Holman, S. L., Hammond, S. J., Perumal, S. R., Macgowan, C. K., . . . Morrison, J. L. (2024). Acute-on-chronic: using magnetic resonance imaging to disentangle the haemodynamic responses to acute and chronic fetal hypoxaemia. Frontiers in Medicine, 11, 1340012-1-1340012-14.
DOI WoS1
2024 Meakin, A. S., Nathanielsz, P. W., Li, C., Huber, H. F., Clifton, V. L., Wiese, M. D., & Morrison, J. L. (2024). Maternal obesogenic diet during pregnancy and its impact on fetal hepatic function in baboons. Obesity (Silver Spring), 32(10), 1910-1922.
DOI Scopus5 WoS4 Europe PMC5
2024 Meakin, A. S., Nathanielsz, P. W., Li, C., Clifton, V. L., Wiese, M. D., & Morrison, J. L. (2024). Maternal obesity impacts fetal liver androgen signalling in a sex-specific manner. Life Sciences, 337(122344), 122344-1-122344-9.
DOI Scopus10 WoS9 Europe PMC7
2024 Robinson, J. L., Gatford, K. L., Clifton, V. L., Morrison, J. L., & Stark, M. J. (2024). The impact of maternal asthma on the fetal lung: Outcomes, mechanisms and interventions. Paediatric Respiratory Reviews, 51, 38-45.
DOI Scopus9 WoS6 Europe PMC5
2024 Meakin, A. S., Smith, M., Morrison, J. L., Roberts, C. T., Lappas, M., Ellery, S. J., . . . Clifton, V. L. (2024). Placenta-Specific Transcripts Containing Androgen Response Elements Are Altered In Silico by Male Growth Outcomes. International Journal of Molecular Sciences, 25(3), 1688-1-1688-13.
DOI Scopus1
2024 Robinson, J. L., Gatford, K. L., Bailey, D. N., Roff, A. J., Clifton, V. L., Morrison, J. L., & Stark, M. J. (2024). Preclinical models of maternal asthma and progeny outcomes: a scoping review. European Respiratory Review, 33(171, article no. 230174), 230174-1-230174-14.
DOI Scopus2 WoS1 Europe PMC1
2024 Meakin, A. S., Gatford, K. L., Lien, Y. -C., Wiese, M. D., Simmons, R. A., & Morrison, J. L. (2024). Characterisation of ciclesonide metabolism in human placentae across gestation. Placenta, 154, 42-48.
DOI Scopus1 WoS1 Europe PMC1
2023 Padhee, M., Lock, M. C., McMillen, I. C., Zhang, S., Botting, K. J., Nyengaard, J. R., . . . Morrison, J. L. (2023). Sex-specific effects of in vitro culture and embryo transfer on cardiac growth in sheep offspring. Journal of Molecular and Cellular Cardiology Plus, 5(100039), 100039-1-100039-12.
DOI Scopus3 WoS2 Europe PMC2
2023 Meakin, A. S., Amirmostofian, M., Darby, J. R., Holman, S. L., Morrison, J. L., & Wiese, M. D. (2023). Characterisation of cytochrome P450 isoenzyme activity in sheep liver and placental microsomes. Placenta, 131, 82-89.
DOI Scopus3 WoS3 Europe PMC2
2023 Robinson, J. L., Gatford, K. L., Hurst, C. P., Clifton, V. L., Morrison, J. L., & Stark, M. J. (2023). Do improvements in clinical practice guidelines alter pregnancy outcomes in asthmatic women? A single-center retrospective cohort study.. Journal of Asthma, 60(10), 1907-1917.
DOI Scopus5 WoS5 Europe PMC5
2023 Paramasivan, S., Morrison, J. L., Lock, M. C., Darby, J. R. T., Barrero, R. A., Mills, P. C., & Sadowski, P. (2023). Automated proteomics workflows for high-throughput library generation and biomarker detection using data-independent acquisition. Journal of proteome research, 22(6), 2018-2029.
DOI Scopus7 WoS7 Europe PMC6
2023 Robinson, J. L., Gatford, K. L., Clifton, V. L., Morrison, J. L., & Stark, M. J. (2023). Preclinical models of maternal asthma and progeny outcomes: a scoping review protocol. JBI Evidence Synthesis, 21(10), 2115-2126.
DOI Scopus1 WoS1 Europe PMC1
2023 Darby, J. R. T., Zhang, S., Holman, S. L., Muhlhausler, B. S., McMillen, I. C., & Morrison, J. L. (2023). Cardiac growth and metabolism of the fetal sheep are not vulnerable to a 10 day increase in fetal glucose and insulin concentrations during late gestation. Heliyon, 9(7), e18292-1-e18292-14.
DOI Scopus5 WoS5 Europe PMC5
2023 Dimasi, C. G., Darby, J. R. T., & Morrison, J. L. (2023). A change of heart: understanding the mechanisms regulating cardiac proliferation and metabolism before and after birth. Journal of Physiology, 601(8), 1319-1341.
DOI
2023 Lock, M. C., Botting, K. J., Allison, B. J., Niu, Y., Ford, S. G., Murphy, M. P., . . . Morrison, J. L. (2023). MitoQ as an antenatal antioxidant treatment improves markers of lung maturation in healthy and hypoxic pregnancy. Journal of Physiology, 601(16), 3647-3665.
DOI Scopus13 WoS14 Europe PMC11
2023 Saini, B. S., Ducas, R., Darby, J. R. T., Marini, D., Sun, L., Macgowan, C. K., . . . Seed, M. (2023). Feasibility of MRI assessment of maternal-fetal oxygen transport and consumption relative to maternal position in healthy late gestational pregnancies. Journal of Physiology, 601(23), 5413-5436.
DOI Scopus4 Europe PMC4
2023 Kühle, H., Cho, S. K. S., Barber, N., Goolaub, D. S., Darby, J. R. T., Morrison, J. L., . . . Seed, M. (2023). Advanced imaging of fetal cardiac function. Frontiers in Cardiovascular Medicine, 10(1206138), 1-16.
DOI Scopus13 Europe PMC13
2023 Darby, J. R. T., Williams, G. K., Cho, S. K. S., Meakin, A. S., Holman, S. L., Quinn, M., . . . Morrison, J. L. (2023). Acute resveratrol exposure does not impact hemodynamics of the fetal sheep. Physiological Reports, 11(12), 12 pages.
DOI Scopus5 WoS5 Europe PMC5
2022 Morrison, J. L., Williams, G. K., Cho, S. K. S., Saini, B. S., Meakin, A. S., Holman, S. L., . . . Darby, J. R. T. (2022). MRI Characterization of Blood Flow and Oxygen Delivery in the Fetal Sheep whilst Exposed to Sildenafil Citrate. Neonatology, 119(6), 735-744.
DOI Scopus8 WoS8 Europe PMC8
2022 Charest Pekeski, A. J., Cho, S. K. S., Aujla, T., Sun, L., Quinn, M., Darby, J. R. T., . . . Haller, C. (2022). Impact of the addition of a centrifugal pump in a preterm miniature pig model of the artificial placenta. Frontiers in Physiology, 13(article number 925772), 1-17.
DOI Scopus12 Europe PMC11
2022 Flouri, D., Darby, J. R. T., Holman, S. L., Cho, S. K. S., Dimasi, C. G., Perumal, S. R., . . . Morrison, J. L. (2022). Placental MRI predicts fetal oxygenation and growth rates in sheep and human pregnancy. Advanced Science, 9(30, article no. 2203738), 1-14.
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2022 Meakin, A. S., Darby, J. R. T., Holman, S. L., Wiese, M. D., & Morrison, J. L. (2022). Maternal-placental-fetal drug metabolism is altered by late gestation undernutrition in the pregnant ewe. Life Sciences, 298(article no. 120521), 1-9.
DOI Scopus15 WoS13 Europe PMC8
2022 Darby, J. R. T., Chiu, J., Regnault, T. R. H., & Morrison, J. L. (2022). Placental insufficiency induces a sexually dimorphic response in the expression of cardiac growth and metabolic signalling molecules upon exposure to a postnatal western diet in guinea pigs. Journal of Developmental Origins of Health and Disease, 13(3), 345-357.
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2022 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Giussani, D. A. (2022). Molecular regulation of lung maturation in near-term fetal sheep by maternal daily vitamin C treatment in late gestation. Pediatric Research, 91(4), 828-838.
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2022 Zhang, W. Q., Sorvina, A., Morrison, J. L., Darby, J. R. T., Brooks, D. A., Plush, S. E., & Afshar Vahid, S. (2022). Development of an optical fiber-based redox monitoring system for tissue metabolism. Journal of Biophotonics, 15(4, article no, e202100304), 1-11.
DOI Scopus2 WoS2 Europe PMC1
2022 Wiese, M. D., Berry, M. J., Hissaria, P., Darby, J. R. T., & Morrison, J. L. (2022). COVID-19: Can we treat the mother without harming her baby?. Journal of Developmental Origins of Health and Disease, 13(1), 9-19.
DOI Scopus6 WoS5 Europe PMC5
2022 Ward, S. J., Hill, A. M., Buckley, J. D., Banks, S., Dhillon, V. S., Holman, S. L., . . . Coates, A. M. (2022). Minimal changes in telomere length after a 12-week dietary intervention with almonds in mid-age to older, overweight and obese Australians: Results of a randomised clinical trial. British Journal of Nutrition, 127(6), 872-884.
DOI Scopus6 WoS7 Europe PMC5
2021 Roff, A. J., Morrison, J. L., Tai, A., Clifton, V. L., & Gatford, K. L. (2021). Maternal asthma during pregnancy and risks of allergy and asthma in progeny: a systematic review protocol.. JBI evidence synthesis, Publish Ahead of Print(8), 2007-2013.
DOI Scopus4 WoS3 Europe PMC3
2021 Paget, T. L., Parkinson-Lawrence, E. J., Trim, P. J., Autilio, C., Panchal, M. H., Koster, G., . . . Orgeig, S. (2021). Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse.. Cells, 10(4), 849.
DOI Scopus8 WoS7 Europe PMC5
2021 Meakin, A. S., Cuffe, J. S. M., Darby, J. R. T., Morrison, J. L., & Clifton, V. L. (2021). Let’s talk about placental sex, baby: Understanding mechanisms that drive female-and male-specific fetal growth and developmental outcomes. International Journal of Molecular Sciences, 22(12), 6386-1-6386-17.
DOI Scopus112 WoS107 Europe PMC103
2021 Gillam, T. A., Caporale, C., Brooks, R. D., Bader, C. A., Sorvina, A., Werrett, M. V., . . . Plush, S. E. (2021). Neutral Re(I) complex platform for live intracellular imaging. Inorganic Chemistry, 60(14), 10173-10185.
DOI Scopus14 WoS14 Europe PMC8
2021 Dimasi, C. G., Lazniewska, J., Plush, S. E., Saini, B. S., Holman, S. L., Cho, S. K. S., . . . Darby, J. R. T. (2021). Redox ratio in the left ventricle of the growth restricted fetus is positively correlated with cardiac output. Journal of Biophotonics, 14(12, article no. e202100157), 1-13.
DOI Scopus16 WoS16 Europe PMC15
2021 McBride, G. M., Meakin, A. S., Soo, J. Y., Darby, J. R. T., Varcoe, T. J., Bradshaw, E. L., . . . Morrison, J. L. (2021). Intrauterine growth restriction alters the activity of drug metabolising enzymes in the maternal-placental-fetal unit. Life Sciences, 285(120016), 1-9.
DOI Scopus21 WoS20 Europe PMC16
2021 Wiese, M. D., Meakin, A. S., Varcoe, T. J., Darby, J. R. T., Sarr, O., Kiser, P., . . . Morrison, J. L. (2021). Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight. Life Sciences, 287(120133), 120133-1-120133-11.
DOI Scopus8 WoS8 Europe PMC5
2021 Darby, J. R. T., Varcoe, T. J., Holman, S. L., McMillen, I. C., & Morrison, J. L. (2021). The reliance on α‐adrenergic receptor stimuli for blood pressure regulation in the chronically hypoxaemic fetus is not dependent on post‐ganglionic activation. The Journal of Physiology, 599(4), 1307-1318.
DOI Scopus10 WoS10 Europe PMC7
2021 Lazniewska, J., Darby, J. R. T., Holman, S. L., Sorvina, A., Plush, S. E., Massi, M., . . . Morrison, J. L. (2021). In utero substrate restriction by placental insufficiency or maternal undernutrition decreases optical redox ratio in foetal perirenal fat. Journal of Biophotonics, 14(4), e202000322-1-e202000322-13.
DOI Scopus4 WoS3 Europe PMC2
2021 Ren, J., Lock, M. C., Darby, J. R. T., Orgeig, S., Holman, S. L., Quinn, M., . . . Morrison, J. L. (2021). PPARγ activation in late gestation does not promote surfactant maturation in the fetal sheep lung. Journal of Developmental Origins of Health and Disease, 12(6), 963-974.
DOI Scopus4 WoS12 Europe PMC3
2021 Meakin, A. S., Morrison, J. L., Bradshaw, E. L., Holman, S. L., Saif, Z., Gatford, K. L., . . . Clifton, V. L. (2021). Identification of placental androgen receptor isoforms in a sheep model of maternal allergic asthma. Placenta, 104, 232-235.
DOI Scopus10 WoS9 Europe PMC5
2021 Padhee, M., McMillen, C., Zhang, S., Armitage, J. A., Head, G. A., MacLaughlin, S. M., . . . Morrison, J. L. (2021). Impact of in vitro embryo culture and transfer on blood pressure regulation in the adolescent lamb. Journal of Developmental Origins of Health and Disease, 12(5), 731-737.
DOI Scopus3 WoS3 Europe PMC3
2021 Lock, M. C., Botting, K. J., Niu, Y., Ford, S. G., Orgeig, S., Giussani, D. A., & Morrison, J. L. (2021). Dexamethasone reduces 11b-hydroxysteroid dehydrogenase 1 expression the fetal lung following hypoxic pregnancy. Reproductive Sciences, 28(S1), 260.
2021 Charest Pekeski, A. J., Sheta, A., Taniguchi, L., McVey, M. J., Aujla, T., Cho, S. K. S., . . . Haller, C. (2021). Achieving sustained extrauterine life: challenges of an artificial placenta in fetal pigs as a model of the preterm human fetus. Physiological Reports, 9(5, article number e14742), 1-20.
DOI Scopus27 Europe PMC19
2021 Ren, J., Darby, J. R. T., Lock, M. C., Holman, S. L., Saini, B. S., Bradshaw, E. L., . . . Morrison, J. L. (2021). Impact of maternal late gestation undernutrition on surfactant maturation, pulmonary blood flow and oxygen delivery measured by magnetic resonance imaging in the sheep fetus. Journal of Physiology, 599(20), 4705-4724.
DOI Scopus11 WoS8 Europe PMC8
2021 Schrauben, E. M., Darby, J. R. T., Berry, M. J., Saini, B. S., Quinn, M., Holman, S. L., . . . Morrison, J. L. (2021). Open or closed: Changes in ductus arteriosus flow patterns at birth using 4D flow MRI in newborn piglets. Physiological Reports, 9(17), 15 pages.
DOI Scopus5 WoS5 Europe PMC6
2021 Saini, B. S., Darby, J. R. T., Marini, D., Portnoy, S., Lock, M. C., Soo, J. Y., . . . Seed, M. (2021). An MRI approach to assess placental function in healthy humans and sheep. The Journal of Physiology, 599(10), 2573-2602.
DOI Scopus26 WoS23 Europe PMC24
2021 Aujla, T., Darby, J. R. T., Saini, B. S., Lock, M. C., Holman, S. L., Bradshaw, E. L., . . . Morrison, J. L. (2021). Impact of resveratrol-mediated increase in uterine artery blood flow on fetal haemodynamics, blood pressure and oxygenation in sheep. Experimental Physiology, 106(5), 1166-1180.
DOI Scopus9 WoS9 Europe PMC9
2021 Morrison, J. L., Darby, J. R. T., & Michael, N. (2021). Themed issue on the DOHaD workshop on fetal, placental and pediatric imaging. Journal of Developmental Origins of Health and Disease, 12(2), 151-152.
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2021 Flouri, D., Darby, J. R. T., Holman, S. L., Perumal, S. R., David, A. L., Morrison, J. L., & Melbourne, A. (2021). Magnetic resonance imaging of placentome development in the pregnant ewe. Placenta, 105, 61-69.
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2021 South, A. M., Alexander, B. T., Morrison, J. L., & Sehgal, A. (2021). Fetal growth restriction, nutrition, and the renin-angiotensin system-reply. Journal Of Pediatrics, 230, 275-276.
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2021 Darby, J. R. T., Berry, M. J., Quinn, M., Holman, S. L., Bradshaw, E. L., Jesse, S. M., . . . Morrison, J. L. (2021). Haemodynamics and cerebral oxygenation of neonatal piglets in the immediate ex utero period supported by mechanical ventilation or ex utero oxygenator. Journal of Physiology, 599(10), 2751-2761.
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2020 Schrauben, E. M., Darby, J. R. T., Saini, B. S., Holman, S. L., Lock, M. C., Perumal, S. R., . . . Macgowan, C. K. (2020). Technique for comprehensive fetal hepatic blood flow assessment in sheep using 4D flow MRI. Journal of Physiology, 598(17), 3555-3567.
DOI Scopus9 WoS9 Europe PMC9
2020 Darby, J. R. T., Schrauben, E. M., Saini, B. S., Holman, S. L., Rajan Perumal, S., Seed, M., . . . Morrison, J. L. (2020). Umbilical vein infusion of Prostaglandin I2 increases ductus venosus shunting of oxygen rich blood but does not increase cerebral oxygen delivery in the fetal sheep. The Journal of Physiology, 598(21), 4957-4967.
DOI
2020 Cho, S. K. S., Darby, J. T. R., Saini, B. S., Lock, M. C., Holman, S. L., Lim, J. M., . . . Seed, M. (2020). Feasibility of ventricular volumetry by cardiovascular MRI to assess cardiac function in the fetal sheep. The Journal of Physiology, 598(13), 2557-2573.
DOI Scopus24 WoS22 Europe PMC20
2020 Saini, B. S., Darby, J. R. T., Portnoy, S., Sun, L., van Amerom, J., Lock, M. C., . . . Seed, M. (2020). Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging. The Journal of Physiology, 598(15), 3259-3281.
DOI Scopus59 WoS53 Europe PMC49
2020 Reynolds, C. M., & Morrison, J. L. (2020). Editorial: Outcomes from the 2018 Australia and New Zealand developmental origins of health and disease (ANZ DOHaD) scientific meeting. Journal of developmental origins of health and disease, 11(3), 199-200.
DOI
2020 Bansal, A., & Morrison, J. L. (2020). The Journal of Developmental Origins of Health and Disease (JDOHaD) celebrates the contribution of women in DOHaD on International Women's Day. Journal of Developmental Origins of Health and Disease, 97(2), 97-98.
DOI
2020 Soo, J. Y., Wiese, M. D., Dyson, R. M., Gray, C. L., Clarkson, A. N., Morrison, J. L., & Berry, M. J. (2020). Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs. PLoS ONE, 15(5, article no. e0233010), 1-16.
DOI
2020 Sehgal, A., Alexander, B. T., Morrison, J. L., & South, A. M. (2020). Fetal growth restriction and hypertension in the offspring: mechanistic links and therapeutic directions. Journal of Pediatrics, 224, 115.e2-123.e2.
DOI
2020 Darby, J. R. T., Varcoe, T. J., Orgeig, S., & Morrison, J. L. (2020). Cardiorespiratory consequences of intrauterine growth restriction: influence of timing, severity and duration of hypoxaemia. Theriogenology, 150, 84-95.
DOI Scopus54 WoS49 Europe PMC40
2020 Jones, A. R., Tuckwell, C., Wright, I. M. R., Morrison, J. L., Kandasamy, Y., Wittwer, M. R., . . . Clifton, V. L. (2020). The impact of maternal asthma during pregnancy on offspring retinal microvascular structure and its relationship to placental growth factor production in utero. Microcirculation, 27(6), 1-10.
DOI Scopus3 WoS3
2020 Lock, M. C., Tellam, R. L., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Seed, M., . . . Morrison, J. L. (2020). Identification of novel miRNAs involved in cardiac repair following infarction in fetal and adolescent sheep hearts. Frontiers in Physiology, 11(article no. 614), 614-1-614-21.
DOI Scopus9 WoS9 Europe PMC8
2020 McBride, G. M., Wiese, M. D., Soo, J. Y., Darby, J. R., Berry, M. J., Varcoe, T. J., & Morrison, J. L. (2020). The impact of intrauterine growth restriction on cytochrome P450 enzyme expression and activity. Placenta, 99, 50-62.
DOI Scopus12 WoS12 Europe PMC8
2020 Muhlhausler, B., Morrison, J., Wlodek, M., Tolcos, M., McGillick, E., Armitage, J., . . . Bertram, J. (2020). DOHaD in the land down under: 11th World Congress 2019. Journal of Developmental Origins of Health and Disease, 11(16), 543-544.
DOI
2020 Morrison, J. L., Ayonrinde, O. T., Care, A. S., Clarke, G. D., Darby, J. R. T., David, A. L., . . . Velan, S. S. (2020). Seeing the fetus from a DOHaD perspective: Discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress. Journal of Developmental Origins of Health and Disease, 12(2), 1-15.
DOI Scopus6 WoS5 Europe PMC4
2020 McBride, G. M., Soo, J. Y., Varcoe, T., Morrison, J. L., & Wiese, M. D. (2020). Development of a method to determine cytochrome P450 1A2, 2C9, 2D6 and 3A4 activity sheep hepatic microsomes. Journal of Pharmacological and Toxicological Methods, 106, 106934-1-106934-8.
DOI Scopus7 WoS7 Europe PMC4
2020 Copping, K. J., Hernandez-Medrano, J., Hoare, A., Hummitzsch, K., McMillen, I. C., Morrison, J., . . . Perry, V. (2020). Maternal periconceptional and first trimester protein restriction in beef heifers: effects on placental parameters and fetal and neonatal calf development. Reproduction, Fertility and Development, 32(5), 495-507.
DOI Scopus21 WoS19 Europe PMC13
2020 Varcoe, T. J., Darby, J. R. T., Holman, S. L., Bradshaw, E. L., Kuchel, T., Vaughan, L., . . . Morrison, J. L. (2020). Fetal cardiovascular response to acute hypoxia during maternal anesthesia. Physiological reports, 8(3), e14365.
DOI Scopus14 Europe PMC12
2020 Darby, J. R. T., Sorvina, A., Bader, C. A., Lock, M. C., Soo, J. Y., Holman, S. L., . . . Morrison, J. L. (2020). Detecting metabolic differences in fetal and adult sheep adipose and skeletal muscle tissues. Journal of Biophotonics, 13(3), e201960085-1-e201960085-13.
DOI Scopus16 WoS17 Europe PMC14
2020 Lock, M. C., Tellam, R. L., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Macgowan, C. K., . . . Morrison, J. L. (2020). Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart. Physiological Genomics, 52(3), 143-159.
DOI Scopus6 WoS5 Europe PMC4
2019 Lock, M. C., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Perumal, S. R., Selvanayagam, J. B., . . . Morrison, J. L. (2019). Differential response to injury in fetal and adolescent sheep hearts in the immediate post in the immediate post-myocardial myocardial myocardial infarction period. Frontiers in Physiology, 10(208), 208-1-208-24.
DOI Scopus31 WoS32 Europe PMC31
2019 Wooldridge, A. L., Clifton, V. L., Moss, T. J. M., Lu, H., Jamali, M., Agostino, S., . . . Gatford, K. L. (2019). Maternal allergic asthma during pregnancy alters fetal lung and immune development in sheep: potential mechanisms for programming asthma and allergy. Journal of Physiology, 597(16), 4251-4262.
DOI Scopus19 WoS16 Europe PMC12
2019 Clifton, V. L., McDonald, M., Morrison, J. L., Holman, S. L., Lock, M. C., Saif, Z., . . . Moss, T. J. M. (2019). Placental glucocorticoid receptor isoforms in a sheep model of maternal allergic asthma. Placenta, 83, 33-36.
DOI Scopus17 WoS17 Europe PMC14
2019 Varcoe, T. J., Darby, J. R. T., Gatford, K. L., Holman, S. L., Cheung, P., Berry, M. J., . . . Morrison, J. L. (2019). Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery. Animal Frontiers, 9(3), 60-67.
DOI Scopus34 WoS32 Europe PMC28
2019 Berry, M. J., Darby, J. R. T., O'Byrne, D. M., Dyson, R. M., Sixtus, R., Holman, S. L., . . . Morrison, J. L. (2019). Arginine Vasopressin improves cerebral perfusion following controlled haemorrhage in adult ewes. The journal of physiology, 597(16), 4165-4173.
DOI
2019 Darby, J. R. T., Saini, B. S., Soo, J. Y., Lock, M. C., Holman, S. L., Bradshaw, E. L., . . . Morrison, J. L. (2019). Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth. The journal of physiology, 597(20), 5063-5077.
DOI Scopus40 WoS39 Europe PMC34
2019 Duan, A. Q., Darby, J. R. T., Soo, J. Y., Lock, M. C., Zhu, M. Y., Flynn, L. V., . . . Seed, M. (2019). Feasibility of phase-contrast cine magnetic resonance imaging for measuring blood flow in the sheep fetus. American journal of physiology - Regulatory integrative and comparative physiology, 317(6), R780-R792.
DOI Scopus36 WoS36 Europe PMC25
2019 Darby, J. R. T., & Morrison, J. L. (2019). And the beat goes on.... Journal of physiology, 596(21), 5073-5074.
DOI
2019 Schrauben, E. M., Saini, B. S., Darby, J. R. T., Soo, J. Y., Lock, M. C., Stirrat, E., . . . MacGowan, C. K. (2019). Fetal hemodynamics and cardiac streaming assessed by 4D flow cardiovascular magnetic resonance in fetal sheep. Journal of cardiovascular magnetic resonance, 21(article no 8), 1-11.
DOI Scopus51 WoS53 Europe PMC48
2019 Singh, G., Morrison, J., & Hoy, W. (2019). DOHaD in Indigenous populations: DOHaD, epigenetics, equity and race. Journal of Developmental Origins of Health and Disease, 10(1), 63-64.
DOI Scopus14 WoS11 Europe PMC3
2019 Darby, J. R. T., Mohd Dollah, M. H. B., Regnault, T. R. H., Williams, M. T., & Morrison, J. L. (2019). Systematic review: impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications-are we ready for the clinic?. Pharmacological research, 144, 264-278.
DOI Scopus37 WoS36 Europe PMC27
2018 Soo, J. Y., Wiese, M. D., Berry, M. J., & Morrison, J. L. (2018). Does poor fetal growth influence the extent of fetal exposure to maternal medications?. Pharmacological research, 130, 74-84.
DOI
2018 Soo, J. Y., Wiese, M. D., Berry, M. J., McMillen, I. C., & Morrison, J. L. (2018). Intrauterine growth restriction may reduce hepatic drug metabolism in the early neonatal period. Pharmacological research, 134, 68-78.
DOI
2018 Darby, J. R. T., McMillen, I. C., & Morrison, J. L. (2018). Maternal undernutrition in late gestation increases IGF2 signalling molecules and collagen deposition in the right ventricle of the fetal sheep heart. Journal of physiology, 596(12), 2345-2358.
DOI
2018 Morrison, J., Botting, K., Darby, J., David, A., Dyson, R., Gatford, K., . . . Berry, M. (2018). Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic. The Journal of Physiology, 596(23), 5535-5569.
DOI Scopus116 WoS113 Europe PMC116
2018 Gillam, T., Sweetman, M., Bader, C., Morrison, J., Hayball, J., Brooks, D., & Plush, S. (2018). Bright lights down under: metal ion complexes turning the spotlight on metabolic processes at the cellular level. Coordination Chemistry Reviews, 375, 234-255.
DOI Scopus9 WoS7
2018 Morrison, J., Sorvina, A., Darby, J., Bader, C., Lock, M., Seed, M., . . . Brooks, D. (2018). Label-free imaging of redox status and collagen deposition showing metabolic differences in the heart. Journal of Biophotonics, 11(3), e20170024-12-e201700242-7.
DOI Scopus5 WoS6 Europe PMC4
2018 Lock, M. C., Tellam, R. L., Botting, K. J., Wang, K. C. W., Selvanayagam, J. B., Brooks, D. A., . . . Morrison, J. L. (2018). The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults. The Journal of Physiology, 596(23), 5625-5640.
DOI Scopus45 WoS38 Europe PMC36
2018 Sorvina, A., Bader, C. A., Darby, J. R. T., Lock, M. C., Soo, J. Y., Johnson, I. R. D., . . . Brooks, D. A. (2018). Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex. Scientific Reports, 8(1, article no. 8191), 8191-1-8191-8.
DOI Scopus33 WoS29 Europe PMC22
2018 Morrison, J. L., Berry, M. J., Botting, K. J., Darby, J. R., Frasch, M. G., Gatford, K. L., . . . Tellam, R. L. (2018). Improving pregnancy outcomes in humans through studies in sheep. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 315(6), 1123-1153.
DOI Scopus148 WoS141 Europe PMC129
2018 Sorvina, A., Bader, C., Lock, M., Brooks, D., Morrison, J., & Plush, S. (2018). Label-free imaging of healthy and infarcted fetal sheep hearts by two-photon microscopy. Journal of Biophotonics, 11(1), e201600296-1-e201600296-8.
DOI Scopus6 WoS4 Europe PMC5
2018 Botting, K. J., Loke, X. Y., Zhang, S., Andersen, J. B., Nyengaard, J. R., & Morrison, J. L. (2018). IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex-and cause-of-IUGR-specific manner. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 315(1), 48-67.
DOI Scopus52 WoS48 Europe PMC44
2018 Warland, J., Dorrian, J., Morrison, J. L., & O'Brien, L. M. (2018). Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis. Sleep Medicine Reviews, 41, 197-219.
DOI Scopus183 WoS159 Europe PMC140
2018 Warland, J., Dorrian, J., Kember, A. J., Phillips, C., Borazjani, A., Morrison, J. L., & O’Brien, L. M. (2018). Modifying maternal sleep position in late pregnancy through positional therapy: A feasibility study. Journal of Clinical Sleep Medicine, 14(8), 1387-1397.
DOI Scopus23 WoS22 Europe PMC16
2017 Wang, K., Botting, K., Zhang, S., McMillen, C., Brooks, D., & Morrison, J. (2017). Akt signaling as a mediator of cardiac adaptation to low birth weight. Journal of Endocrinology, 233(2), R81-R94.
DOI Scopus17 WoS18 Europe PMC15
2017 Stevens, K., Bader, C., Sorvina, A., Brooks, D., Plush, S., & Morrison, J. (2017). Imaging and lipidomics methods for lipid analysis in metabolic and cardiovascular disease. Proceedings of the Scientific Meeting on Australia and New Zealand Developmental Origins of Health and Disease (2016 ANZ DOHaD), as published in Journal of Developmental Origins of Health and Disease, 8(5), 566-574.
DOI Scopus4 WoS3 Europe PMC3
2017 Lock, M., McGillick, E., Orgeig, S., McMillen, I., Mühlhäusler, B., Zhang, S., & Morrison, J. (2017). Differential effects of late gestation maternal overnutrition on the regulation of surfactant maturation in fetal and postnatal life. The Journal of physiology, 595(21), 6635-6652.
DOI Scopus24 WoS23 Europe PMC22
2017 Caporale, C., Bader, C., Sorvina, A., MaGee, K., Skelton, B., Gillam, T., . . . Massi, M. (2017). Investigating intracellular localisation and cytotoxicity trends for neutral and cationic iridium tetrazolato complexes in live cells. Chemistry - A European Journal, 23(62), 15666-15679.
DOI Scopus53 WoS50 Europe PMC25
2017 Soo, J., Orgeig, S., McGillick, E., Zhang, S., McMillen, I., & Morrison, J. (2017). Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old. PLoS ONE, 12(9), e0181185.
DOI Scopus10 WoS9 Europe PMC9
2017 Leggett, C., Costi, L., Morrison, J., Clifton, V., & Grzeskowiak, L. (2017). Antidepressant use in late gestation and breastfeeding rates at discharge from hospital. Journal of Human Lactation, 33(4), 701-709.
DOI Scopus15 WoS12 Europe PMC11
2017 Lock, M. C., Botting, K. J., Tellam, R. L., Brooks, D., & Morrison, J. L. (2017). Adverse intrauterine environment and cardiac miRNA expression. International Journal of Molecular Sciences, 18(12), 2628-1-2628-19.
DOI Scopus26 WoS24 Europe PMC19
2017 Ghazanfar, S., Vuocolo, T., Morrison, J. L., Nicholas, L. M., McMillen, I. C., Yang, J. Y. H., . . . Tellam, R. L. (2017). Gene expression allelic imbalance in ovine brown adipose tissue impacts energy homeostasis. PLoS ONE, 12(6), e0180378.
DOI Scopus9 WoS9 Europe PMC12
2017 McGillick, E. V., Lock, M. C., Orgeig, S., & Morrison, J. (2017). Maternal obesity mediated predisposition to respiratory complications at birth and in later life: understanding the implications of the obesogenic intrauterine environment. Paediatric respiratory reviews, 21, 11-18.
DOI Scopus51 WoS45 Europe PMC38
2017 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Morrison, J. L. (2017). Maternal chronic hypoxia increases expression of genes regulating lung liquid movement and surfactant maturation in male fetuses in late gestation. Journal of Physiology, 595(13), 4329-4350.
DOI
2017 Duan, A. Q., Lock, M. C., Perumal, S. R., Darby, J. R., Soo, J. Y., Selvanayagam, J. B., . . . Morrison, J. L. (2017). Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging. Journal of cardiovascular magnetic resonance, 19(1, article no, 69), 1-11.
DOI Scopus35 WoS32 Europe PMC31
2017 Dickinson, H., & Morrison, J. L. (2017). Australian perspectives: outcomes from the 2016 ANZ DOHaD Scientific Meeting. Journal of developmental origins of health and disease, 8(5), 510-511.
DOI
2017 McGillick, E. V., Orgeig, S., Giussani, D. A., & Morrison, J. L. (2017). Chronic hypoxaemia as a molecular regulator of fetal lung development: implications for risk of respiratory complications at birth. Paediatric respiratory reviews, 21, 3-10.
DOI
2017 Darby, J., McMillen, C., & Morrison, J. (2017). Maternal undernutrition increases fibrosis in the late gestation fetal heart. Heart, Lung and Circulation, 26(S2), 107.
DOI
2017 Orgeig, S., McGillick, E. V., Allison, B. J., Brain, K. L., Niu, Y. G., Itani, N., . . . Morrison, J. L. (2017). Antenatal vitamin C administration in sheep is protective against fetal hypoxemia-induced oxidative stress and airway remodelling in early adulthood. Respirology, 22(S2), 68.
2016 Lock, M., Tellam, R., Porrello, E., Soo, J., Darby, J., Brooks, D., & Morrison, J. (2016). miR-133a and target gene expression in the foetus and 6 month old sheep heart in response to myocardial infarction. Heart, lung and circulation, 25(S2), 117.
DOI
2016 Dickinson, H., & Morrison, J. L. (2016). Australian perspectives: outcomes from the 2015 Australia and New Zealand Developmental Origins of Health and Disease (ANZ DOHaD) scientific meeting. Journal of developmental origins of health and disease, 7(5), 432.
DOI
2016 Morrison, J., & Regnault, T. R. H. (2016). Nutrition in pregnancy: optimising maternal diet and fetal adaptations to altered nutrient supply. Nutrients, 8(6, article no. 342), 1-5.
DOI
2016 McGillick, E. V., Orgeig, S., Williams, M. T., & Morrison, J. L. (2016). Risk of respiratory distress syndrome and efficacy of glucocorticoids: are they the same in the normally grown and growth-restricted infant?. Reproductive sciences, 23(11), 1459-1472.
DOI Scopus24 WoS20 Europe PMC17
2016 Morrison, J. L. (2016). Is there a dirty side to personal care products?. Endocrinology, 157(7), 2575-2577.
DOI
2016 Orgeig, S., Morrison, J. L., & Daniels, C. B. (2016). Evolution, development, and function of the pulmonary surfactant system in normal and perturbed environments. Comprehensive Physiology, 6(1), 363-422.
DOI
2016 McGillick, E. V., Orgeig, S., & Morrison, J. L. (2016). Structural and molecular regulation of lung maturation by intratracheal vascular endothelial growth factor administration in the normally grown and placentally restricted fetus. Journal of physiology, 594(5), 1399-1420.
DOI
2016 McGillick, E. V., Orgeig, S., & Morrison, J. L. (2016). Regulation of lung maturation by prolyl hydroxylase domain inhibition in the lung of the normally grown and placentally restricted fetus in late gestation. American journal of physiology, 310(11), 1226-1243.
DOI
2016 Lie, S., Morrison, J. L., Williams-Wyss, O., Suter, C. M., Humphreys, D. T., Ozanne, S. E., . . . McMillen, I. C. (2016). Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses. American Journal of Physiology: Endocrinology and Metabolism, 310(2), E148-E159.
DOI Scopus12 WoS11 Europe PMC9
2016 Dickinson, H., Moss, T., Gatford, K., Moritz, K., Akison, L., Fullston, T., . . . Morrison, J. (2016). A review of fundamental principles for animal models of DOHaD research: an Australian perspective. Journal of Developmental Origins of Health and Disease, 7(5), 449-472.
DOI Scopus94 WoS95 Europe PMC78
2016 Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., . . . Bagniewska-Zadworna, A. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), 1-222.
DOI Scopus4570 WoS3817 Europe PMC4060
2016 Bazargan, M., Foster, D., Muhlhausler, B., Morrison, J., McMillen, C., & Davey, A. (2016). Limited fetal metabolism of rosiglitazone: elimination via the maternal compartment in the pregnant ewe. Reproductive Toxicology, 61, 162-168.
DOI Scopus8 WoS5 Europe PMC4
2016 Zhang, S., Barker, P., Botting, K., Roberts, C., McMillan, C., McMillen, I., & Morrison, J. (2016). Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia. Physiological Reports, 4(23), e13049-1-e13049-19.
DOI Scopus42 WoS40 Europe PMC36
2016 Clifton, V., Moss, T., Wooldridge, A., Gatford, K., Liravi, B., Kim, D., . . . Bischof, R. (2016). Development of an experimental model of maternal allergic asthma during pregnancy. Journal of Physiology, 594(5), 1311-1325.
DOI Scopus25 WoS22 Europe PMC18
2016 Grzeskowiak, L., Morrison, J., Henriksen, T., Bech, B., Obel, C., Olsen, J., & Pedersen, L. (2016). Prenatal antidepressant exposure and child behavioural outcomes at 7 years of age: a study within the Danish National Birth Cohort. BJOG: An International Journal of Obstetrics and Gynaecology, 123(12), 1919-1928.
DOI Scopus46 WoS29 Europe PMC28
2016 Nicholas, L., Morrison, J., Rattanatray, L., Zhang, S., Ozanne, S., & McMillen, I. (2016). The early origins of obesity and insulin resistance: Timing, programming and mechanisms. International Journal of Obesity, 40(2), 229-238.
DOI Scopus128 WoS102 Europe PMC99
2015 Grzeskowiak, L., Hodyl, N., Stark, M., Morrison, J., & Clifton, V. (2015). Association of early and late maternal smoking during pregnancy with offspring body mass index at 4 to 5 years of age. Journal of Developmental Origins of Health and Disease, 6(6), 485-492.
DOI Scopus15 WoS12 Europe PMC12
2015 van Dijk, S., Tellam, R., Morrison, J., Muhlhausler, B., & Molloy, P. (2015). Recent developments on the role of epigenetics in obesity and metabolic disease. Clinical Epigenetics, 7(article no. 66), 66-1-66-13.
DOI Scopus177 WoS155 Europe PMC133
2015 Kleemann, D., Kelly, J., Rudiger, S., McMillen, I., Morrison, J., Zhang, S., . . . Walker, S. (2015). Effect of periconceptional nutrition on the growth, behaviour and survival of the neonatal lamb. Animal Reproduction Science, 160, 12-22.
DOI Scopus19 WoS20 Europe PMC11
2015 Lie, S., Morrison, J., Williams-Wyss, O., Suter, C., Humphreys, D., Ozanne, S., . . . McMillen, I. (2015). Impact of periconceptional and preimplantation undernutrition on factors regulating myogenesis and protein synthesis in muscle of singleton and twin fetal sheep. Physiological Reports, 3(8), e12495-1-e12495-15.
DOI Scopus12 WoS11 Europe PMC8
2015 Morrison, J., Zhang, S., Tellam, R., Brooks, D., McMillen, I., Porrello, E., & Botting, K. (2015). Regulation of microRNA during cardiomyocyte maturation in sheep. BMC Genomics, 16(1), 541-1-541-15.
DOI Scopus18 WoS22 Europe PMC18
2015 Wang, K., Brooks, D., Summers-Pearce, B., Bobrovskaya, L., Tosh, D., Duffield, J., . . . Morrison, J. (2015). Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life. Physiological Reports, 3(2), e12270-1-e12270-16.
DOI Scopus23 WoS19 Europe PMC19
2015 Lock, M., McGillick, E., Orgeig, S., Zhang, S., McMillen, I., & Morrison, J. (2015). Mature Surfactant Protein-B Expression by Immunohistochemistry as a Marker for Surfactant System Development in the Fetal Sheep Lung. Journal of Histochemistry and Cytochemistry, 63(11), 866-878.
DOI Scopus25 WoS23 Europe PMC19
2015 Poudel, R., McMillen, I., Dunn, S., Zhang, S., & Morrison, J. (2015). Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 308(3), 151-162.
DOI Scopus114 WoS104 Europe PMC85
2015 Orgeig, S., McGillick, E., Botting, K., Zhang, S., McMillen, I., & Morrison, J. (2015). Increased lung prolyl hydroxylase and decreased glucocorticoid receptor are related to decreased surfactant protein in the growth-restricted sheep fetus. American Journal of Physiology-Lung Cellular and Molecular Physiology, 309(1), L84-L97.
DOI Scopus42 WoS35 Europe PMC34
2015 Zhang, S., Regnault, T., Barker, P., Botting, K., McMillen, I., McMillan, C., . . . Morrison, J. (2015). Placental adaptations in growth restriction. Nutrients, 7(1), 360-389.
DOI Scopus200 WoS181 Europe PMC151
2015 Wang, K., Tosh, D., Zhang, S., McMillen, I., Duffield, J., Brooks, D., & Morrison, J. (2015). IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 308(7), R627-R635.
DOI Scopus34 WoS34 Europe PMC29
2015 Padhee, M., Zhang, S., Lie, S., Wang, K., Botting, K., Caroline McMillen, I., . . . Morrison, J. (2015). The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health?. Nutrients, 7(3), 1378-1425.
DOI Scopus34 WoS35 Europe PMC30
2015 Van Dijk, S., Molloy, P., Varinli, H., Morrison, J., Muhlhausler, B., Buckley, M., . . . Tellam, R. (2015). Epigenetics and human obesity. International Journal of Obesity, 39(1), 85-97.
DOI Scopus290 WoS263 Europe PMC220
2015 Kohlmeier, K. A., Morrison, J. L., & Kristensen, M. P. (2015). Postnatal consequences of prenatal nicotine exposure. Journal of developmental origins of health and disease, 6(3), 161-162.
DOI
2015 Harvey, T. J., Murphy, R. M., Morrison, J. L., & Posterino, G. S. (2015). Maternal nutrient restriction alters Ca2+ handling properties and contractile function of isolated left ventricle bundles in male but not female juvenile rats. PLoS ONE, 10(9, article no. 0138388), 1-18.
DOI
2015 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Giussani, D. A. (2015). Maternal antioxidant treatment increases expression of genes regulating hypoxia signalling, sodium movement and surfactant maturation in the fetal lung. Reproductive sciences, 22(no. 0-073), 80A.
2015 Darby, J., Zhang, S., McMillen, I., Mühlhausler, B., & Morrison, J. (2015). Late gestation over nutrition alters the cardiac metabolic profile. Heart, Lung and Circulation, 24(S3), S189.
DOI
2014 Lie, S., Morrison, J., Williams-Wyss, O., Suter, C., & Roberts, C. (2014). Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep. Biology of Reproduction, 90(1), 1-10.
DOI Scopus52 WoS40 Europe PMC29
2014 Lie, S., Hui, M., McMillen, I., Muhlhausler, B., Posterino, G., Dunn, S., . . . Morrison, J. (2014). Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 306(6), R429-R437.
DOI Scopus20 WoS20 Europe PMC20
2014 Botting, K., McMillen, I., Forbes, H., Nyengaard, J., & Morrison, J. (2014). Chronic hypoxemia in late gestation decreases cardiomyocyte number but does not change expression of hypoxia-responsive genes. Journal of the American Heart Association, 3(4), e000531-1-e000531-14.
DOI Scopus102 WoS97 Europe PMC91
2014 Lie, S., Morrison, J., Williams-Wyss, O., Suter, C., Humphreys, D., Ozanne, S., . . . McMillen, I. (2014). Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep. American Journal of Physiology: Endocrinology and Metabolism, 306(9), E1013-E1024.
DOI Scopus48 WoS46 Europe PMC41
2014 Williams-Wyss, O., Zhang, S., MacLaughlin, S., Kleemann, D., Walker, S., Suter, C., . . . Caroline McMillen, I. (2014). Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development. American Journal of Physiology: Endocrinology and Metabolism, 307(2), E141-E150.
DOI Scopus27 WoS23 Europe PMC21
2014 Lee, A., Morrison, J., Botting, K., Shandala, T., & Xian, C. (2014). Effects of maternal hypoxia during pregnancy on bone development in offspring: a guinea pig model. International Journal of Endocrinology, 2014(article no. 916918), 916918-1-916918-12.
DOI Scopus9 WoS9 Europe PMC9
2014 Rattanatray, L., Muhlhausler, B., Nicholas, L., Morrison, J., & McMillen, I. (2014). Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver. Pediatric Research, 75(1), 14-21.
DOI Scopus11 WoS13 Europe PMC10
2014 Nicholas, L., Rattanatray, L., Morrison, J., Kleemann, D., Walker, S., Zhang, S., . . . McMillen, I. (2014). Maternal obesity or weight loss around conception impacts hepatic fatty acid metabolism in the offspring. Obesity, 22(7), 1685-1693.
DOI Scopus21 WoS21 Europe PMC20
2014 McGillick, E. V., Morrison, J. L., McMillen, I. C., & Orgeig, S. (2014). Intrafetal glucose infusion alters glucocorticoid signalling and reduces surfactant protein mRNA expression in the lung of the late gestation sheep fetus. American Journal of Physiology : Regulatory, Integrative and Comparative Physiology, 307(5), R538-R545.
DOI Scopus48 Europe PMC38
2013 Lock, M., McGillick, E. V., Orgeig, S., McMillen, I. C., & Morrison, J. L. (2013). Regulation of fetal lung development in response to maternal overnutrition. Clinical and experimental pharmacology and physiology, 40(11), 803-816.
DOI Scopus43 WoS39 Europe PMC32
2013 McGillick, E. V., Orgeig, S., McMillen, I. C., & Morrison, J. L. (2013). The fetal sheep lung does not respond to cortisol infusion during the late canalicular phase of development. Physiological reports, 1(6, article no. e00130), 1-15.
DOI Scopus50
2013 Grzeskowiak, L. E., & Morrison, J. L. (2013). Long-term effects of prenatal SSRI exposure on child growth: weighing the evidence. American Journal of Psychiatry, 170(11), 1364.
DOI Scopus1 WoS1 Europe PMC1
2013 Grzeskowiak, L., Gilbert, A., Sorensen, T., Olsen, J., Sorensen, H., Pedersen, L., & Morrison, J. (2013). Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age. Annals of Epidemiology, 23(11), 681-687.
DOI Scopus21 WoS17 Europe PMC18
2013 Grzeskowiak, L. E., Gilbert, A. L., & Morrison, J. L. (2013). Methodological challenges in using routinely collected health data to investigate long-term effects of medication use during pregnancy. Therapeutic Advances in Drug Safety, 4(1), 27-37.
DOI Scopus15 WoS15 Europe PMC14
2013 Nicholas, L., Morrison, J., Rattanatray, L., Ozanne, S., Kleemann, D., Walker, S., . . . McMillen, I. (2013). Differential effects of exposure to maternal obesity or maternal weight loss during the periconceptional period in the sheep on insulin signalling molecules in skeletal muscle of the offspring at 4 months of age. PLoS One, 8(12), 1-11.
DOI Scopus34 WoS32 Europe PMC25
2013 Zhang, S., Morrison, J., Gill, A., Rattanatray, L., MacLaughlin, S., Kleemann, D., . . . McMillen, I. (2013). Maternal dietary restriction during the periconceptional period in normal-weight or obese ewes results in adrenocortical hypertrophy, an up-regulation of the JAK/STAT and down-regulation of the IGF1R signaling pathways in the adrenal of the postnatal lamb. Endocrinology, 154(12), 4650-4662.
DOI Scopus24 WoS23 Europe PMC17
2013 Wang, K., Lim, C., McMillen, I., Duffield, J., Brooks, D., & Morrison, J. (2013). Alteration of cardiac glucose metabolism in association to low birth weight: experimental evidence in lambs with left ventricular hypertrophy. Metabolism-clinical and Experimental, 62(11), 1662-1672.
DOI Scopus53 WoS51 Europe PMC48
2013 Lie, S., Morrison, J., Wyss, O., Ozanne, S., Zhang, S., Walker, S., . . . McMillen, I. (2013). Impact of embryo number and periconceptional undernutrition on factors regulating adipogenesis, lipogenesis, and metabolism in adipose tissue in the sheep fetus. American Journal of Physiology-Endocrinology and Metabolism, 305(8), 931-941.
DOI Scopus16 WoS16 Europe PMC12
2013 Zhang, S., Morrison, J., Gill, A., Rattanatray, L., MacLaughlin, S., Kleemann, D., . . . McMillen, I. (2013). Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in the adrenal of the offspring. Reproduction, 146(5), 443-454.
DOI Scopus19 WoS20 Europe PMC15
2013 Nicholas, L., Rattanatray, L., MacLaughlin, S., Ozanne, S., Kleemann, D., Walker, S., . . . McMillen, I. (2013). Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring. The FASEB Journal, 27(9), 3786-3796.
DOI Scopus100 WoS93 Europe PMC82
2013 Zhang, S., Wyss, O., MacLaughlin, S., Walker, S., Kleemann, D., Suter, C., . . . McMillen, I. (2013). Maternal undernutrition during the first week after conception results in decreased expression of glucocorticoid receptor mRNA in the absence of GR exon 1₇ hypermethylation in the fetal pituitary in late gestation. Journal of Developmental Origins of Health and Disease, 4(5), 391-401.
DOI Scopus11 WoS11 Europe PMC9
2013 Lie, S., Sim, S., McMillen, I., Wyss, O., MacLaughlin, S., Kleemann, D., . . . Morrison, J. (2013). Maternal undernutrition around the time of conception and embryo number each impact on the abundance of key regulators of cardiac growth and metabolism in the fetal sheep heart. Journal of Developmental Origins of Health and Disease, 4(5), 377-390.
DOI Scopus23 WoS22 Europe PMC20
2013 Lie, S., Duffield, J., McMillen, I., Morrison, J., Ozanne, S., Pilgrim, C., & Muhlhausler, B. (2013). The effect of placental restriction on insulin signaling and lipogenic pathways in omental adipose tissue in the postnatal lamb. Journal of Developmental Origins of Health and Disease, 4(5), 421-429.
DOI Scopus6 WoS6 Europe PMC4
2013 Morrison, J. L., Suter, C., Botting, K. J., & Nyengaard, J. R. (2013). Does maternal obesity change cardiomyocyte endowment?. Expert Review of Obstetrics and Gynecology, 8(1), 1-3.
DOI
2013 Grzeskowiak, L. E., Pedersen, L. H., & Morrison, J. L. (2013). Antidepressant use and gestational hypertension: does evidence support causality?. British Journal of Clinical Pharmacology, 75(5), 1373-1374.
DOI Scopus4 WoS4 Europe PMC3
2013 Morrison, J. L., Lumbers, E., Bennet, L., & Black, J. (2013). Introduction: Celebrating Emeritus Scientia Professor Eugenie R Lumbers AM and Professor Caroline McMillen. Clinical and experimental pharmacology and physiology, 40(11), 740-742.
DOI
2013 Regnault, T. R. H., Nijland, M. J., Budge, H., & Morrison, J. L. (2013). Basic experimental and clinical advances in the mechanisms underlying abnormal pregnancy outcomes. Journal of Pregnancy, 2013(327638), 1-3.
DOI
2012 Wang, K., Brooks, D., Pearce, B., Bobrovskaya, L., Duffield, J., McMillen, C., & Morrison, J. (2012). Impact with low birth weight on the expression of the renin-angiotensin system, factors which regulate autophagy, fibrosis and capillary density in the heart during early postnatal life. Journal of hypertension, 30(Supplement 1), 76.
DOI
2012 Grzeskowiak, L., Gilbert, A., & Morrison, J. (2012). Prenatal exposure to selective serotonin reuptake inhibitors and risk of childhood overweight. Journal of Developmental Origins of Health and Disease, 3(4), 253-261.
DOI Scopus19 WoS18 Europe PMC17
2012 Morrison, J. L., & Botting, K. J. (2012). Does a growth-restricted fetus have fewer cardiomyocytes than a normally grown fetus?. Expert reviews in obstetrics and gynecology, 7(4), 301-303.
DOI
2012 Morrison, J. L., Botting, K. J., Soo, P. S., McGillick, E. V., Hiscock, J., Zhang, S., . . . Orgeig, S. (2012). Antenatal steroids and the IUGR fetus: are exposure and physiological effects on the lung and cardiovascular system the same as in normally grown fetuses?. Journal of pregnancy, 2012(839656), 1-15.
DOI Scopus78 WoS61 Europe PMC44
2012 Wang, K., Brooks, D., Thornburg, K., & Morrison, J. (2012). Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus. Journal of Physiology, 590(21), 5425-5437.
DOI Scopus39 WoS39 Europe PMC37
2012 Wang, K., Botting, K., Padhee, M., Zhang, S., McMillen, I., Suter, C., . . . Morrison, J. (2012). Early origins of heart disease: low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy. Clinical and Experimental Pharmacology and Physiology, 39(11), 958-964.
DOI Scopus21 WoS19 Europe PMC15
2012 Botting, K., Wang, K., Padhee, M., McMillen, I., Pearce, B., Rattanatray, L., . . . Morrison, J. (2012). Early origins of heart disease: low birth weight and determinants of cardiomyocyte endowment. Clinical and Experimental Pharmacology and Physiology, 39(9), 814-823.
DOI Scopus77 WoS73 Europe PMC72
2012 Wang, K., Brooks, D., Botting, K., & Morrison, J. (2012). IGF-2R-mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep. Biology of Reproduction, 86(6), 1-8.
DOI Scopus28 WoS28 Europe PMC25
2012 Soo, P., Hiscock, J., Botting, K., Roberts, C., Davey, A., & Morrison, J. (2012). Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation. Reproductive Toxicology, 33(3), 374-381.
DOI Scopus81 WoS78 Europe PMC72
2012 Grzeskowiak, L., Gilbert, A., & Morrison, J. (2012). Neonatal outcomes after late-gestation exposure to selective serotonin reuptake inhibitors. Journal of Clinical Psychopharmacology, 32(5), 615-621.
DOI Scopus46 WoS43 Europe PMC41
2012 Grzeskowiak, L. E., Gilbert, A. L., & Morrison, J. L. (2012). Long term impact of prenatal exposure to SSRIs on growth and body weight in childhood: evidence from animal and human studies. Reproductive Toxicology, 34(1), 101-109.
DOI Scopus29 WoS27 Europe PMC26
2012 Grzeskowiak, L., Gilbert, A., & Morrison, J. (2012). Investigating outcomes associated with medication use during pregnancy: a review of methodological challenges and observational study designs. Reproductive Toxicology, 33(3), 280-289.
DOI Scopus26 WoS24 Europe PMC23
2012 Grzeskowiak, L., Gilbert, A., & Morrison, J. (2012). Exposed or not exposed? Exploring exposure classification in studies using administrative data to investigate outcomes following medication use during pregnancy. European Journal of Clinical Pharmacology, 68(5), 459-467.
DOI Scopus49 WoS48 Europe PMC39
2012 Morrison, J. L., & Gordon, A. (2012). Drugs, chemicals and nutrition during pregnancy : impact on fetal, neonatal and adult health. Journal of developmental origins of health and disease, 3(4), 213-215.
DOI
2011 Grzeskowiak, L., Gilbert, A., & Morrison, J. (2011). Investigating outcomes following the use of selective serotonin reuptake Inhibitors for treating depression in pregnancy a focus on methodological issues. Drug Safety, 34(11), 1027-1048.
DOI Scopus30 WoS30 Europe PMC26
2011 Wang, K., Zhang, L., McMillen, I., Botting, K., Duffield, J., Zhang, S., . . . Morrison, J. (2011). Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb. Journal of Physiology-London, 589(19), 4709-4722.
DOI Scopus79 WoS78 Europe PMC69
2011 Bazargan, M., Davey, A., Muhlhausler, B., Morrison, J., McMillen, I., & Foster, D. (2011). Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model. Journal of Pharmaceutical and Biomedical Analysis, 55(2), 360-365.
DOI Scopus13 WoS13 Europe PMC9
2011 Zhang, S., Rattanatray, L., McMillen, I. C., Suter, C. M., & Morrison, J. L. (2011). Periconceptional nutrition and the early programming of a life of obesity or adversity. Progress in biophysics and molecular biology, 106(1), 307-314.
DOI Scopus54 WoS47 Europe PMC34
2011 Posterino, G., Dunn, S., Botting, K., Wang, W., Gentili, S., & Morrison, J. (2011). Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus. Journal of Applied Physiology, 111(1), 236-243.
DOI Scopus18 WoS16 Europe PMC15
2011 Zhang, S., Rattanatray, L., Morrison, J., Nicholas, L., Lie, S., & McMillen, I. (2011). Maternal obesity and the early origins of childhood obesity: Weighing up the benefits and costs of maternal weight loss in the periconceptional period for the offspring. Experimental Diabetes Research, 2011(585749), 10 pages.
DOI Scopus62 WoS57 Europe PMC40
2011 Orgeig, S., Morrison, J. L., & Daniels, C. B. (2011). Prenatal development of the pulmonary surfactant system and the influence of hypoxia. Respiratory physiology and neurobiology, 178(1), 129-145.
DOI
2010 Orgeig, S., & Morrison, J. L. (2010). Does the intrauterine growth-restricted fetus benefit from antenatal glucocorticoids. Expert reviews in obstetrics and gynecology, 5(2), 149-152.
DOI
2010 Grzeskowiak, L., Gilbert, A. L., & Morrison, J. L. (2010). Conception and beyond : using population-based record linkage to monitor long-term effects of medications used during pregnancy. Journal of pharmacy practice and research, 40(1), 46-49.
DOI Scopus7
2010 Grzeskowiak, L., Morrison, J. L., & Gilbert, A. L. (2010). Hospital pharmacy dispensing records for pharmacoepidemiology research into late gestation exposure to antidepressants. Journal of pharmacy practice and research, 40(4), 265-268.
DOI Scopus10
2010 Zhang, S., Rattanatray, L., MacLaughlin, S., Cropley, J., Suter, C., Molloy, L., . . . McMillen, I. (2010). Periconceptional undernutrition in normal and overweight ewes leads to increased adrenal growth and epigenetic changes in adrenal IGF2/H19 gene in offspring. FASEB Journal, 24(8), 2772-2782.
DOI Scopus100 WoS89 Europe PMC82
2010 Nguyen, L., Muhlhausler, B., Botting, K., & Morrison, J. (2010). Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus. Placenta, 31(10), 902-909.
DOI Scopus23 WoS22 Europe PMC20
2010 Morrison, J., Duffield, J., Muhlhausler, B., Gentili, S., & McMillen, I. (2010). Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity. Pediatric Nephrology, 25(4), 669-677.
DOI Scopus161 WoS152 Europe PMC130
2010 Orgeig, S., Crittenden, T. A., Marchant, C., McMillen, I. C., & Morrison, J. L. (2010). Intrauterine growth restriction delays surfactant protein maturation in the sheep fetus. American journal of physiology : lung cellular and molecular physiology, 298(4), L575-L583.
DOI Scopus99 Europe PMC74
2009 Dyer, J. L., McMillen, I. C., Warnes, K. E., & Morrison, J. L. (2009). No evidence for an enhanced role of endothelial nitric oxide in the maintenance of arterial blood pressure in the IUGR sheep fetus. Placenta, 30(8), 705-710.
DOI Scopus29 Europe PMC25
2009 Gentili, S., Morrison, J. L., & McMillen, I. C. (2009). Intrauterine growth restriction and differential patterns of hepatic growth and expression of IGF1, PCK2, and HSDL1 mRNA in the sheep fetus in late gestation. Biology of reproduction, 80(6), 1121-1127.
DOI Scopus66 WoS65 Europe PMC59
2009 Muhlhausler, B., Duffield, J., Ozanne, S., Pilgrim, C., Turner, N., Morrison, J., & McMillen, I. (2009). The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle. Journal of Physiology-London, 587(17), 4199-4211.
DOI Scopus92 WoS85 Europe PMC79
2009 Muhlhausler, B., Morrison, J., & McMillen, I. (2009). Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-γ target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation. Endocrinology, 150(9), 4287-4294.
DOI Scopus36 WoS34 Europe PMC31
2009 McMillen, I., Rattanatray, L., Duffield, J., Morrison, J., MacLaughlin, S., Gentili, S., & Muhlhausler, B. (2009). The early originis of later obesity: pathways and mechanisms. Advances in experimental medicine and biology, 646, 71-82.
DOI Scopus90 WoS84 Europe PMC73
2009 Morrison, J. L., Wang, K. C. W., Brooks, D. A., & Botting, K. J. (2009). Fetal heart growth: IGF-1 and sex. Expert review of obstetrics and gynecology, 4(3), 255-259.
DOI
2009 Morrison, J. L., & Orgeig, S. (2009). Antenatal glucocorticoid treatment of the growth-restricted fetus : benefit or cost?. Reproductive sciences, 16(6), 527-538.
DOI
2008 Morrison, J. L. (2008). Sheep models of intrauterine growth restriction: Fetal adaptations and consequences. Clinical and experimental pharmacology and physiology, 35(7), 730-743.
DOI
2008 Snell, A., McMillen, I. C., Gentili, S., & Morrison, J. L. (2008). The effect of hypoxia on NGF expression in the aorta and femoral artery in the growth restricted sheep fetus. Reproductive sciences, 15(1, article no. 224), 124.
2008 Wallace, S., Morrison, J., Botting, K., & Kee, T. (2008). Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments. Journal of Biomedical Optics, 13(6), 1.
DOI Scopus27 WoS24 Europe PMC18
2008 McMillen, I., MacLaughlin, S., Muhlhausler, B., Gentili, S., Duffield, J., & Morrison, J. (2008). Developmental origins of adult health and disease: The role of periconceptional and foetal nutrition. Basic ' Clinical Pharmacology ' Toxicology, 102(2), 82-89.
DOI Scopus217 WoS192 Europe PMC158
2007 Morrison, J., Botting, K., Wright, J., Williams, S., Thornburg, K., & McMillen, I. (2007). Restriction of placental function alters heart development in the sheep fetus. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 293(1), R306-R313.
DOI Scopus166 WoS153 Europe PMC139
2006 Morrison, J. L. (2006). Two-day subpressor cortisol infusion increases proliferation of cardiomyocytes in the late gestation sheep fetus. Expert reviews in obstetrics and gynecology, 1(2), 145-148.
DOI
2006 Spencer, T. N., Botting, K. J., Morrison, J. L., & Posterino, G. S. (2006). Contractile and Ca2+-handling properties of the right ventricular papillary muscle in the late-gestation sheep fetus. Journal of applied physiology, 101(3), 728-733.
DOI
2005 Sood, S., Morrison, J. L., Liu, H., & Horner, R. (2005). Role of endogenous serotonin in modulating genioglossus muscle activity in awake and sleeping rats. American journal of respiratory and critical care medicine, 172(10), 1338-1347.
DOI
2005 Morrison, J. L., Carmichael, L., Homan, J., White, S., & Richardson, B. (2005). Cerebral blood flow during spontaneous and cholinergically induced behavioral states in the sheep fetus. Pediatric research, 57(5 Part 1), 667-673.
DOI
2005 Morrison, J. L., Riggs, K., & Rurak, D. (2005). Fluoxetine during pregnancy: impact on fetal development.. Reproduction, fertility, and development, 17(6), 641-650.
DOI
2005 Schwartz, I., & Morrison, J. L. (2005). Impact and mechanisms of fetal physiological programming. American journal of physiology: regulatory, integrative and comparative physiology, 288(1), R11-R15.
DOI
2005 Danielson, L., McMillen, I., Wright, J., & Morrison, J. (2005). Restriction of placental growth results in greater hypotensive response to ?- adrenergic blockade in fetal sheep during late gestation. Journal of Physiology-London, 563(2), 611-620.
DOI Scopus94 Europe PMC81
2005 Morrison, J., Rurak, D., Chien, C., Kennaway, D., Gruber, N., McMillen, I., & Riggs, K. (2005). Maternal fluoxetine infusion does not alter fetal endocrine and biophysical circadian rhythms in pregnant sheep. Journal of the Society for Gynecologic Investigation, 12(5), 356-364.
DOI Scopus17 WoS17 Europe PMC13
2004 Morrison, J., Riggs, K., Chien, C., Gruber, N., McMillen, I., & Rurak, D. (2004). Chronic maternal fluoxetine infusion in pregnant sheep: effects on the maternal and fetal hypothalamic-pituitary-adrenal axes. Pediatric Research, 56(1), 40-46.
DOI Scopus40 Europe PMC35
2003 Liu, X., Sood, S., Liu, H., Nolan, P., Morrison, J. L., & Horner, R. (2003). Suppression of genioglossus muscle tone and activity during reflex hypercapnic stimulation by GABA(A) mechanisms at the hypoglossal motor nucleus in vivo. Neuroscience, 116(1), 249-259.
DOI
2003 Morrison, J. L., Sood, S., Liu, H., Park, E., Liu, X., Nolan, P., & Horner, R. (2003). Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats. Journal of physiology, 552(3), 975-991.
DOI
2003 Morrison, J. L., Sood, S., Liu, H., Park, E., Nolan, P., & Horner, R. (2003). GABA(A) receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM not REM sleep. Journal of physiology, 548(2), 569-583.
DOI
2002 Morrison, J. L., Chien, C., Riggs, K., Gruber, N., & Rurak, D. (2002). Effect of maternal fluoxetine administration on uterine blood flow, fetal blood gas status, and growth. Pediatric research, 51(4), 433-442.
DOI
2002 Morrison, J. L., Sood, S., Liu, X., Liu, H., Park, E., Nolan, P., & Horner, R. (2002). Glycine at hypoglossal motor nucleus. Journal of applied physiology, 93(5), 1786-1796.
DOI
2001 Morrison, J. L., Chien, C., Gruber, N., Rurak, D., & Riggs, K. (2001). Fetal behavioural state changes following maternal fluoxetine infusion in sheep. Developmental brain research, 131(1-2), 47-56.
DOI

Year Citation
2024 McGillick, E. V., Morrison, J. L., Parkinson Lawrence, E. J., & Paget, T. L. (2024). The development and function of the pulmonary surfactant system in health, prematurity, and genetic disease. In Source details - Title: The Lung: Development, Aging and the Environment (pp. 159-201). UK: Academic Press.
DOI
2024 McGillick, E. V., Morrison, J. L., & Orgeig, S. (2024). Effect of environment on the developing and adult pulmonary surfactant system and in the aging lung. In Source details - Title: The Lung: Development, Aging and the Environment (pp. 505-542). UK: Academic Press.
DOI
2020 Saini, B. S., Morrison, J. L., & Seed, M. (2020). Gas exchange across the placenta. In S. Lapinsky, & L. Plante (Eds.), Source details - Title: Respiratory Disease in Pregnancy (pp. 34-56). UK: Cambridge University Press.
DOI
2015 Orgeig, S., Morrison, J., & Daniels, C. B. (2015). Effect of environment and aging on the pulmonary surfactant system. In R. Harding, & K. Pinkerton (Eds.), Source details - Title: The lung: development, aging and the enivronment (2 ed., pp. 447-470). Amsterdam: Academic Press.
DOI
2014 Orgeig, S., Morrison, J. L., Sullivan, L. C., & Daniels, C. B. (2014). The development of the pulmonary surfactant system. In R. Harding, & K. E. Pinkerton (Eds.), Source details - Title: The lung: development, aging and the environment (2nd ed ed., pp. 183-210). UK: Academic Press.
DOI
2014 Morrison, J. L., & Wright, I. M. R. (2014). Intrauterine Growth Restriction. In W. F. Malcolm (Ed.), Source details - Title: Beyond the NICU : comprehensive care of the high-risk infant (pp. 424-450). US: McGraw-Hill Medical.

Year Citation
2023 Amanollahi, R., Bertossa, M., Holman, S. L., McMillen, I. C., & Morrison, J. L. (2023). Impact of 7-Day Fetal Cortisol Infusion in Mid-Late Gestation on Cardiac Growth in Sheep. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Germany: SPRINGER HEIDELBERG.
2023 Bennett, M. G. A., Meakin, A. S., Botting, K. J., Niu, Y., Ford, S. G., Wiese, M. D., . . . Morrison, J. L. (2023). Programming of Impaired Hepatic Drug Metabolism in Adult Offspring: Effects of Hypoxic Pregnancy and Antioxidant Treatment. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Germany: SPRINGER HEIDELBERG.
2023 Meakin, A., Nathanielsz, P., Li, C., Wiese, M., & Morrison, J. (2023). Maternal Obesity During Pregnancy and Its Impact on Fetal Hepatic Function in Baboons. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Germany: SPRINGER HEIDELBERG.
2023 Darby, J. R. T., Flouri, D., Cho, S. K. S., Williams, G. K., Holman, S. L., Macgowan, C. K., . . . Morrison, J. L. (2023). Maternal tadalafil treatment does not increase uterine artery blood flow or oxygen delivery in the pregnant ewe. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Sarah, H. J., Ahdi, N., Darby, J. R. T., Holman, S. L., Saini, B. S., Macgowan, C. K., . . . Davidson, J. O. (2023). Does low oxygen availability affect oligodendrocyte density in the brain of the growth restricted fetus?. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Bertossa, M. R., Darby, J. R. T., Holman, S. L., Cho, S. K., Macgowan, C. K., Seed, M., & Morrison, J. L. (2023). The impact of maternal undernutrition in late gestation on fetal cardiac remodelling in sheep. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Minns, A., Holman, S. L., Darby, J. R. T., & Morrison, J. L. (2023). The role of endothelial nitric oxide in fetal baroreflex sensitivity in a pregnant sheep model of late gestation undernutrition. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Dimasi, C. G., Darby, J. R. T., Holman, S., Quinn, M., Bradshaw, E. L., Jesse, S. M., & Morrison, J. L. (2023). Developmental origins of cardiac disease: understanding cardiac maturation in pigs. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Roff, A. J., Robinson, J. L., Hammond, S. J., Davies, A., Clifton, V. L., Wallace, M. J., . . . Donnelley, M. (2023). X-ray Velocimetry Detects Changes in Local Airflow in a Sheep Model of Asthma During Pregnancy. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Germany: SPRINGER HEIDELBERG.
2018 Clifton, V. L., Jones, A., Morrison, J., Wright, I. M. R., Kandasamy, Y., Wittwer, M. R., & Arstall, M. A. (2018). Maternal Asthma during Pregnancy is Associated with Altered Retinal Microvascular Structure in Childhood.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. San Diego, CA: SAGE PUBLICATIONS INC.
2017 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Morrison, J. L. (2017). Chronic fetal hypoxaemia & maternal antioxidants: identifying mechanisms and treatments to improve postnatal lung structure & function in growth restricted offspring. Poster session presented at the meeting of Reproductive sciences. US: Sage Publications.
2016 Orgeig, S., Mcgillick, E., & Morrison, J. (2016). Regulation of lung maturation by prolyl hydroxylase domain (PHD) inhibition in the lung of the normally grown and placentally restricted foetus in late gestation. Poster session presented at the meeting of Respirology. Australia: Wiley Blackwell Publishing Asia.
2016 McGillick, E. V., Orgeig, S., Allison, B. J., Brain, K. L., Niu, Y., Itani, N., . . . Morrison, J. L. (2016). Differential effect of early versus late onset chronic hypoxemia on molecular mechanisms regulating lung maturation in the late gestation fetus. Poster session presented at the meeting of Reproductive sciences. US: Sage Publications.
2016 McGillick, E. V., Orgeig, S., & Morrison, J. L. (2016). Understanding delayed surfactant maturation in the chronically hypoxemic intrauterine growth restricted fetus by prolyl hydroxylase domain (PHD) inhibition in late gestation... Poster session presented at the meeting of Reproductive sciences. US: Sage Publications Inc.
DOI
2015 Zhang, S., Harding, J. E., Padhee, M., Botting, K. J., Dunn, S. L., Brooks, D. A., . . . Morrison, J. L. (2015). Does increasing maternal insulin sensitivity during the periconceptional period correct the cardiac deficits induced by interauterine growth restriction in the sheep fetus?. Poster session presented at the meeting of Hypertension. US: Lippincott Williams and Wilkins.
2010 Christiaens, I., Dorian, C., Olson, D. M., & Robertson, S. A. (2010). Interleukin-6 regulates the timing of birth in mice through a direct uterine effect. Poster session presented at the meeting of Scientific abstracts of the 57th Annual Scientific Meeting, as published in Reproductive Sciences. US: SAGE Publications.
DOI
  • Going with the flow: Directing nutrient rich blood to the brain, ARC - Discovery Projects, 01/01/2019 - 31/12/2021

  • Normal heart development before birth, ARC - Future Fellowship, 01/01/2018 - 31/12/2021

  • The haemodynamics of intrauterine growth restriction, Sick Kids Hospital, 01/07/2016 - 30/09/2019

  • Understanding the consequences of impaired cardiac development on heart health after birth, NHMRC - Career Development Fellowship, 01/01/2014 - 31/12/2017

Date Role Research Topic Program Degree Type Student Load Student Name
2025 External Supervisor Oxygen Physiology in Preterm Infants Doctor of Philosophy Doctorate Part Time Mr Chad Andersen
2025 External Supervisor Oxygen Physiology in Preterm Infants Doctor of Philosophy Doctorate Full Time Mr Chad Andersen
2024 External Supervisor Investigating the variable response of preterm infants to treatment with antenatal corticosteroids. Doctor of Philosophy Doctorate Full Time Ms Yoshi Tan
2024 External Supervisor Investigating the variable response of preterm infants to treatment with antenatal corticosteroids. Doctor of Philosophy Doctorate Full Time Ms Yoshi Tan
2024 Co-Supervisor - - Master Full Time Mr David Brock Harman
2024 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mrs Sheila Mizani
2024 Principal Supervisor - - Master Full Time Mr Jesse Thomas Tu
2024 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Laura Jane Hale
2023 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mrs Saba Albetawi
2023 Co-Supervisor - - Master Full Time Mr Troy Gordon Pearce
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Melanie Bertossa
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Sarah Jane Hammond
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Milly Bennett
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mr Jordan Minns
2021 External Supervisor Asthma during pregnancy and pregnancy during asthma Doctor of Philosophy Doctorate Part Time Mrs Andrea Jane Roff
2021 External Supervisor Asthma during pregnancy and pregnancy during asthma Doctor of Philosophy Doctorate Full Time Mrs Andrea Jane Roff
2021 External Supervisor - Doctor of Philosophy Doctorate Full Time Mrs Shaghayegh Baghapour

Date Role Research Topic Program Degree Type Student Load Student Name
2021 - 2024 External Supervisor Evaluating the Impact of Maternal Asthma on Neonatal and Childhood Lung Function and Its Underlying Mechanisms Doctor of Philosophy Doctorate Full Time Mr Joshua Luke Robinson
2010 - 2014 Principal Supervisor The Effect of Prenatal Hypoxia on Cardiomyocyte Development and Postnatal Heart Health Doctor of Philosophy Doctorate Full Time Ms Kimberley Botting