Tara Pukala

Research Interests

Analytical Biochemistry Analytical Chemistry Analytical Spectrometry Biochemistry & Molecular Biology Biologically Active Molecules Characterisation of Biological Macromolecules General Chemistry Medicinal and Biomolecular Chemistry Organic Chemistry Proteins and Peptides Proteomics and Intermolecular Interactions Structural Biology Structural Chemistry and Spectroscopy

Professor Tara Pukala

Professor

Office of Science

College of Science

Tara Pukala obtained a PhD from the University of Adelaide in 2006, under the supervision of Prof John Bowie. This was followed by a postdoctoral position at the University of Cambridge, UK, working with Prof Dame Carol Robinson in the field of native mass spectrometry.Tara returned to Australia to her current role as lecturer in the Discipline of Chemistry at the University of Adelaide in 2008. Here she leads a multidisciplinary research group focused on developing new approaches, primarily utilising mass spectrometry, to investigate the structure, function and interactions of macromolecules important in biology.Since 2017 she has had the role of Scientific Director of the Adelaide Proteomics Centre.

Biological macromolecules such as proteins and DNA form the machinery that underlies all biological functions. The ability to ‘see’ the atomic detail of these assemblies, including their structures and interactions with other molecules, provides an opportunity to understand their biological activity. It also helps unravel processes which have gone astray to cause disease, and therefore find new treatments for a range of human illnesses.

In recent years mass spectrometry has emerged as a powerful tool for structural biology, in many cases capable of exceeding other techniques by diversity in application and information content. This is due to the ability of mass spectrometry to precisely identify biomolecules, binding interactions, detect individual species present in a mixture, and offer conformational information for large, dynamic and heterogeneous structures, with physiological relevance.

Research in the Pukala group is directed towards development of new approaches, primarily using mass spectrometry, to obtain insight into the structure, function and interactions of macromolecules, with a focus on enhancing understanding of multi-molecular systems involved in disease.

Current projects include;

  • development of ion mobility-mass spectrometry (and complementary tools) for the study of large protein complexes
  • design of novel mass spectrometry amenable protein cross-linking strategies
  • mechanistic studies of protein misfolding and aggregation
  • structural analysis of triplex DNA

For more details of current projects, see the Pukala Group website.

Date Position Institution name
2023 - ongoing Professor University of Adelaide
2022 - ongoing Associate Dean of Graduate Studies University of Adelaide
2017 - 2022 Associate Professor University of Adelaide
2012 - 2016 Senior Lecturer University of Adelaide
2008 - 2011 Lecturer University of Adelaide
2007 - 2008 Postdoctoral Research Fellow University of Cambridge

Date Type Title Institution Name Country Amount
2023 Recognition Superstar of STEM Science and Technology Australia Australia -
2021 Research Award Faculty of Sciences Mid Career Research Excellence Award University of Adelaide Australia -
2017 Research Award Australian and New Zealand Society of Mass Spectrometry Bowie Medal Australian and New Zealand Society of Mass Spectrometry Australia -
2014 Teaching Award University of Adelaide Faculty of Sciences Award for Excellence in Teaching University of Adelaide Australia -
2012 Research Award HG Andrewartha Medal Royal Society of South Australia Australia -
2011 Award Young Tall Poppy Science Award Australian Institute of Policy and Science Australia -
2010 Award South Australian Young Achiever (Science and Technology) Awards Australia Australia -
2009 Research Award University of Adelaide Faculty of Sciences Early Career Research Excellence Award University of Adelaide Australia -
2003 Award University of Adelaide Medal University of Adelaide Australia -
2003 Scholarship George Fraser PhD Scholarship University of Adelaide Australia -
2001 Scholarship Ferry Scholarship Cedric Arnold Seth Ferry Trust - -

Date Institution name Country Title
2003 - 2006 University of Adelaide Australia PhD
1999 - 2002 University of Adelaide Australia BSc (Hons)

Year Citation
2025 Pachulicz, R. J., Jovcevski, B., Bulone, V., & Pukala, T. L. (2025). Acid-catalysed esterification of anthocyanin glucosyl units by organic acids: Chemical factors and structural implications. Food Chemistry, 480, 143878-1-143878-8.
DOI Scopus1 WoS1
2025 Pederick, J. L., Kumar, A., Pukala, T. L., & Bruning, J. B. (2025). Functional and structural characterization of Staphylococcus aureus N-acetylglucosamine 1-phosphate uridyltransferase (GlmU) reveals a redox-sensitive acetyltransferase activity.. Protein Sci, 34(4), e70111.
DOI Scopus1 WoS1 Europe PMC3
2025 Matthews, R. K., Nguyen, H. T. L., Yang, F., Pukala, T. L., Evans, J. D., & Shearer, C. J. (2025). La Doping ATaO₃ (A = Li, Na, K) to Improve Performance for Photocatalytic Pollutant Degradation. Chemistry of Materials, 37(10), 3696-3708.
DOI
2025 Rusli, O., Bakels, S., Hes, K., Mun, H., Lloyd Williams, O. H., Pachulicz, R. J., . . . Rijs, N. J. (2025). Gas Phase Mass- and Mobility-Resolved Structures of Metalated Glyphosate Dimers. Journal of the American Society for Mass Spectrometry, 36(6), 1296-1307.
DOI Scopus1 WoS2 Europe PMC1
2025 Noye, T. M., Mittal, P., Price, Z. K., Fewster, A., Williams, G., Pukala, T. L., . . . Ricciardelli, C. (2025). Identification of Proteins Associated with Ovarian Cancer Chemotherapy Resistance Using MALDI-MSI. International Journal of Molecular Sciences, 26(12), 5893.
DOI
2025 Yao, Y., Zhang, J., Duan, X., Zhang, P., Shi, L., Hu, K., . . . Wang, S. (2025). Asymmetrically Tipped MoS₂/CdS Heterostructure for High-Performance Photocatalytic Plastic Reforming. Materials Horizons, 12(18), 7439-7449.
DOI Scopus1 WoS1
2025 Nkurunziza, D., Kumorkiewicz-Jamro, A., Yu, L., Duggan, J., Collins, H., Pukala, T., . . . Coad, B. R. (2025). Differential Release of Biologically Active Cell-Wall-Bound Phenolics from Brewer’s Spent Grain Using Conventional and Deep Eutectic Solvents. ACS Sustainable Chemistry & Engineering, 13(28), 10794-10806.
DOI Scopus1
2025 Tasoulis, T., Wang, C. R., Ellis, S., Pukala, T. L., Sumner, J., Murphy, K., . . . Isbister, G. K. (2025). The Venom Proteome of the Ecologically Divergent Australian Elapid, Southern Death Adder Acanthophis antarcticus. Toxins, 17(7), 352-1-352-19.
DOI Scopus1 WoS1 Europe PMC1
2025 Harratt, A., Wu, W., Strube, P., Ceravolo, J., Beattie, D., Pukala, T., . . . Blencowe, A. (2025). Comparison of Preservatives for the Prevention of Microbial Spoilage of Apple Pomace During Storage. Foods, 14(14), 2438.
DOI
2025 Klose, J. W., Urbina, G., & Pukala, T. L. (2025). Molecular insights into nucleic acid triplexes: methodologies and biological applications. Crit Rev Biochem Mol Biol, 60(4-6), 1-25.
DOI
2025 Sternicki, L. M., Pukala, T. L., Pacholarz, K. J., Barran, P., Booker, G. W., Polyak, S. W., & Wegener, K. L. (2025). Hydrogen-Deuterium Exchange Defines Ligand-Induced Conformational Changes to the Class III Biotin Protein Ligase from Saccharomyces cerevisiae. ChemBioChem, 26(20), e202500439-1-e202500439-12.
DOI
2025 Kumorkiewicz-Jamro, A., Pachulicz, R. J., Fitter, S., Górska, R., Duggan, J., Vandyke, K., . . . Zannettino, A. C. W. (2025). Atriplex hortensis var. 'rubra' extracts and purified amaranthin-type pigments reduce oxidative stress and inflammatory response in LPS-stimulated RAW264.7 cells. Food Chemistry, 462, 14 pages.
DOI Scopus9 WoS9 Europe PMC2
2025 Rusli, O., Lloyd Williams, O. H., Chakraborty, P., Neumaier, M., Hennrich, F., Bakels, S., . . . Rijs, N. J. (2025). Structural complexity of glyphosate and aminomethylphosphonate metal complexes. Physical Chemistry Chemical Physics : PCCP, 27(15), 7519-7531.
DOI Scopus5 WoS5 Europe PMC3
2024 Wang, C. R., Zenaidee, M. A., Snel, M. F., & Pukala, T. L. (2024). Exploring Top-Down Mass Spectrometric Approaches To Probe Forest Cobra (Naja melanoleuca) Venom Proteoforms.. Journal of Proteome Research, 23(10), 4601-4613.
DOI Scopus2 WoS2 Europe PMC2
2024 Wang, C. R., Trim, P. J., Truong, J. X., Snel, M. F., & Pukala, T. L. (2024). Interrogation of three-finger toxin and phospholipase A<inf>2</inf> higher order structures from the forest cobra (Naja melanoleuca) venom using a mass spectrometric approach. International Journal of Mass Spectrometry, 506, 117346.
DOI Scopus1 WoS1
2024 Wang, C. R., Harlington, A. C., Snel, M. F., & Pukala, T. L. (2024). Characterisation of the forest cobra (Naja melanoleuca) venom using a multifaceted mass spectrometric-based approach. BBA: Proteins and Proteomics, 1872(2), 140992-1-140992-10.
DOI Scopus9 WoS9 Europe PMC4
2024 Tasoulis, T., Wang, C. R., Sumner, J., Dunstan, N., Pukala, T. L., & Isbister, G. K. (2024). The Eastern Bandy Bandy Vermicella annulata, expresses high abundance of SVMP, CRiSP and Kunitz protein families in its venom proteome. Journal of Proteomics, 295, 105086-1-105086-11.
DOI Scopus1 WoS1 Europe PMC1
2024 McFarlane, L. O., & Pukala, T. L. (2024). Proteomic Investigation of Cape Cobra (Naja nivea) Venom Reveals First Evidence of Quaternary Protein Structures. Toxins, 16(2), 63.
DOI Scopus7 WoS6 Europe PMC4
2024 Petit, S., Scanlon, A. T., Naikatini, A., & Pukala, T. (2024). Dillenia (Dilleniaceae) pollen heteromorphy and presentation, and implications for pollination by bats.. Ecol Evol, 14(2), e10997.
DOI Scopus3 WoS2 Europe PMC2
2024 Klose, J. W., Begbie, A. J., Toronjo-Urquiza, L., & Pukala, T. L. (2024). Native Mass Spectrometric Insights into the Formation and Stability of DNA Triplexes. Journal of the American Society for Mass Spectrometry, 35(3), 613-621.
DOI Scopus2 WoS2 Europe PMC1
2024 Yao, Y., Wang, Y., Lu, T., Zhang, J., Hu, K., Zhang, H., . . . Wang, S. (2024). In-plane implanting carbon rings into carbon nitride to intrigue nonradical photodegradation. Applied Catalysis B: Environmental, 342, 123363-1-123363-11.
DOI Scopus34 WoS34
2024 Yu, L., Jovcevski, B., Pukala, T. L., & Bulone, V. (2024). Profiling and optimized extraction of bioactive polyphenolic compounds from young, red-fleshed apple using eco-friendly deep eutectic solvents. Food Research International, 187, 114334.
DOI Scopus6 WoS4 Europe PMC4
2024 Wang, C. R., McFarlane, L. O., & Pukala, T. L. (2024). Exploring snake venoms beyond the primary sequence: From proteoforms to protein-protein interactions.. Toxicon, 247, 107841.
DOI Scopus4 WoS5 Europe PMC4
2024 Chandrasegaran, S., Klose, J. W., & Pukala, T. L. (2024). Unraveling DNA Triplex Assembly: Mass Spectrometric Investigation of Modified Triplex Forming Oligonucleotides for Enhanced Gene Targeting. Journal of the American Society for Mass Spectrometry, 35(9), 2056-2063.
DOI Scopus2 WoS2 Europe PMC1
2023 Gee, A. R., Stone, I., Stockdale, T. P., Pukala, T. L., De Voss, J. J., & Bell, S. G. (2023). Efficient biocatalytic C-H bond oxidation: an engineered heme-thiolate peroxygenase from a thermostable cytochrome P450. Chemical Communications, 59(90), 13486-13489.
DOI Scopus9 WoS8 Europe PMC4
2023 Zhou, M., Borotto, N. B., Li, H., Pukala, T. L., & Webb, I. K. (2023). Editorial: Emerging structural proteomics methodologies. Frontiers in Analytical Science, 3, 2 pages.
DOI
2023 Pukala, T. L. (2023). Mass spectrometric insights into protein aggregation. Essays in Biochemistry, 67(2), 243-253.
DOI Scopus13 WoS13 Europe PMC14
2023 Pederick, J. L., Klose, J., Jovcevski, B., Pukala, T. L., & Bruning, J. B. (2023). <i>Escherichia coli</i> YgiC and YjfC Possess Peptide─Spermidine Ligase Activity. Biochemistry, 62(4), 899-911.
DOI Scopus5 WoS5 Europe PMC5
2023 Pachulicz, R. J., Yu, L., Jovcevski, B., Bulone, V., & Pukala, T. L. (2023). Structural Analysis and Identity Confirmation of Anthocyanins in Brassica oleracea Extracts by Direct Injection Ion Mobility-Mass Spectrometry. ACS Measurement Science Au, 3(3), 200-207.
DOI Scopus9 WoS8 Europe PMC4
2023 Miller, J. C., Lee, J. H. Z., Mclean, M. A., Chao, R. R., Stone, I. S. J., Pukala, T. L., . . . Bell, S. G. (2023). Engineering C–C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society, 145(16), 9207-9222.
DOI Scopus20 WoS20 Europe PMC9
2023 Frkic, R. L., Pederick, J. L., Horsfall, A. J., Jovcevski, B., Crame, E. E., Kowalczyk, W., . . . Bruning, J. B. (2023). PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles.. ACS Chemical Biology, 18(5), 1115-1123.
DOI Scopus6 WoS6 Europe PMC10
2023 Hua, Q. Q. H., Young, C., Pukala, T. L., Martino, J. C., Hoffmann, P., Gillanders, B. M., & Doubleday, Z. A. (2023). Better late than never: Optimising the proteomic analysis of field-collected octopus.. PloS one, 18(7), e0288084.
DOI Scopus1 WoS1 Europe PMC1
2023 Rogers, C. A., Gaskin, S. E., Thredgold, L. D., & Pukala, T. L. (2023). An approach to quantify ortho-phthalaldehyde contamination on work surfaces.. Annals of work exposures and health, 67(7), wxad039.
DOI Scopus1 WoS1
2023 Clark, S., Wilton, L., Dawson, J., Chiew, K., Jawahar, M. C., Toben, C., . . . Saleem, M. (2023). Dotting the I’s and crossing the T’s: A South Australian perspective on variability in troponin thresholds for myocarditis risk in clozapine treatment. Schizophrenia Research, 268, 114-117.
DOI Scopus3 WoS3 Europe PMC3
2023 Sanyal, S. K., Pukala, T., Mittal, P., Reith, F., Brugger, J., Etschmann, B., & Shuster, J. (2023). From biomolecules to biogeochemistry: Exploring the interaction of an indigenous bacterium with gold. Chemosphere, 339, 139657-1-139657-12.
DOI Scopus1
2023 Vandborg, B., Holroyd, D. L., Pukala, T., & Bruning, J. B. (2023). Production of recombinant human proliferating cellular nuclear antigen (PCNA) for structural and biophysical characterization. Protein Expression and Purification, 212, 1-7.
DOI Scopus2 WoS2 Europe PMC2
2022 Sanders, H. M., Jovcevski, B., Marty, M. T., & Pukala, T. L. (2022). Structural and mechanistic insights into amyloid-β and α-synuclein fibril formation and polyphenol inhibitor efficacy in phospholipid bilayers. The FEBS Journal, 289(1), 215-230.
DOI Scopus23 WoS23 Europe PMC19
2022 Nguyen, S., Jovcevski, B., Pukala, T. L., & Bruning, J. B. (2022). Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta Crystallographica Section D Structural Biology, 78(2), 1-12.
DOI Scopus8 WoS7 Europe PMC7
2022 Tasoulis, T., Pukala, T. L., & Isbister, G. K. (2022). Investigating toxin diversity and abundance in snake venom proteomes. Frontiers in Pharmacology, 12, 768015-1-768015-13.
DOI Scopus61 WoS58 Europe PMC44
2022 Petit, S., Scanlon, A. T., Naikatini, A., Pukala, T., & Schumann, R. (2022). A novel bat pollination system involving obligate flower corolla removal has implications for global Dillenia conservation.. PloS one, 17(2), 1-16.
DOI Scopus2 WoS3 Europe PMC1
2022 Nguyen, S., Jovcevski, B., Truong, J. Q., Pukala, T. L., & Bruning, J. B. (2022). A structural model of the human plasminogen and Aspergillus fumigatus enolase complex.. Proteins, 90(8), 1509-1520.
DOI Scopus1 WoS2 Europe PMC1
2022 Pukala, T., & Robinson, C. V. (2022). Introduction: Mass Spectrometry Applications in Structural Biology.. Chem Rev, 122(8), 7267-7268.
DOI Scopus11 WoS9 Europe PMC9
2022 Tasoulis, T., Wang, C. R., Sumner, J., Dunstan, N., Pukala, T. L., & Isbister, G. K. (2022). The Unusual Metalloprotease-Rich Venom Proteome of the Australian Elapid Snake Hoplocephalus stephensii. Toxins, 14(5), 314-1-314-21.
DOI Scopus3 WoS3 Europe PMC3
2022 Pachulicz, R. J., Yu, L., Jovcevski, B., Bulone, V., & Pukala, T. L. (2022). Polyphenol characterisation and diverse bioactivities of native Australian lilly pilly (Syzygium paniculatum) extract.. Food & Function, 13(16), 8585-8592.
DOI Scopus7 WoS7 Europe PMC5
2022 Horsley, J. R., Jovcevski, B., Pukala, T. L., & Abell, A. D. (2022). Designer D-peptides targeting the N-terminal region of α-synuclein to prevent parkinsonian-associated fibrilization and cytotoxicity. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1870(10), 140826-1-140826-9.
DOI Scopus10 WoS12 Europe PMC7
2022 Pederick, J. L., Horsfall, A. J., Jovcevski, B., Klose, J., Abell, A. D., Pukala, T. L., & Bruning, J. B. (2022). Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism. Journal of Biological Chemistry, 298(10), 102392-1-102392-16.
DOI Scopus6 WoS7 Europe PMC5
2022 Hull, A., Li, Y., Bartholomeusz, D., Hsieh, W., Tieu, W., Pukala, T. L., . . . Bezak, E. (2022). Preliminary Development and Testing of C595 Radioimmunoconjugates for Targeting MUC1 Cancer Epitopes in Pancreatic Ductal Adenocarcinoma.. Cells, 11(19), 18 pages.
DOI Scopus5 WoS3 Europe PMC3
2022 McNicholas, K., François, M., Liu, J. W., Doecke, J. D., Hecker, J., Faunt, J., . . . Leifert, W. R. (2022). Salivary inflammatory biomarkers are predictive of mild cognitive impairment and Alzheimer’s disease in a feasibility study. Frontiers in Aging Neuroscience, 14, 11 pages.
DOI Scopus16 WoS12 Europe PMC12
2021 Stevens, K. G., McFarlane, L. O., Platts, K., O'Brien-Simpson, N., Li, W., Blencowe, A., . . . Pukala, T. L. (2021). Retro Diels-Alder fragmentation of fulvene-maleimide bioconjugates for mass spectrometric detection of biomolecules. Analytical Chemistry, 93(36), 12204-12212.
DOI Scopus4 WoS4 Europe PMC1
2021 Sajid, M. S., Saleem, S., Jabeen, F., Fatima, B., Zulfikar, M., Ashiq, M. N., . . . Najam-ul-Haq, M. (2021). Iminodiacetic acid (IDA)-generated mesoporous nanopolymer: a template to relate surface area, hydrophilicity, and glycopeptides enrichment. Microchimica Acta, 188(12), 8 pages.
DOI Scopus4 WoS3 Europe PMC1
2021 Pukala, T. L., & Chen, H. (2021). Editorial: Technical and Methodological Advances in Proteomics.. Frontiers in chemistry, 9, 795426.
DOI Scopus2 WoS1 Europe PMC1
2021 Nguyen, S., Jovcevski, B., Pukala, T. L., & Bruning, J. B. (2021). Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.. The FEBS journal, 288(7), 2398-2417.
DOI Scopus8 WoS8 Europe PMC7
2021 Enot, M. M., Weiland, F., Mittal, P., Hoffmann, P., Sillero-Mahinay, M., & Pukala, T. (2021). Differential proteome analysis of the leaves of lead hyperaccumulator, Rhoeo discolor (L. Her.) Hance. Journal of Mass Spectrometry, 56(4), e4689-1-e4689-11.
DOI Scopus10 WoS6 Europe PMC3
2020 Tasoulis, T., Pukala, T. L., & Isbister, G. K. (2020). Comments on proteomic investigations of two Pakistani Naja snake venoms species unravel the venom complexity, posttranslational modifications, and presence of extracellular vesicles. toxins 2020, 12, 669. Toxins, 12(12), 1-3.
DOI Scopus2 WoS2 Europe PMC2
2020 Jovcevski, B., Das, S., Smid, S., & Pukala, T. L. (2020). Polyphenol honokiol and flavone 2′,3′,4′-trihydroxyflavone differentially interact with α-synuclein at distinct phases of aggregation. ACS Chemical Neuroscience, 11(24), 4469-4477.
DOI Scopus18 WoS15 Europe PMC11
2020 Horsley, J. R., Jovcevski, B., Wegener, K. L., Yu, J., Pukala, T. L., & Abell, A. (2020). Rationally Designed Peptide-Based Inhibitor of Aβ42 Fibril Formation and Toxicity: A Potential Therapeutic Strategy for Alzheimer's Disease.. Biochemical Journal, 477(11), 2039-2054.
DOI Scopus35 WoS57 Europe PMC43
2020 Shrestha, S., Zhang, W., Begbie, A. J., Pukala, T. L., & Smid, S. D. (2020). Ecklonia radiata extract containing eckol protects neuronal cells against Aβ1-42 evoked toxicity and reduces aggregate density.. Food Funct, 11(7), 6509-6516.
DOI Scopus16 WoS13 Europe PMC7
2020 Sternicki, L. M., Nguyen, S., Pacholarz, K. J., Barran, P., Pendini, N. R., Booker, G. W., . . . Polyak, S. W. (2020). Biochemical characterisation of class III biotin protein ligases from Botrytis cinerea and Zymoseptoria tritici. Archives of Biochemistry and Biophysics, 691, 108509-1-108509-11.
DOI Scopus3 WoS3 Europe PMC2
2020 Salman Sajid, M., Jovcevski, B., Mittal, P., Fatima, B., Hussain, D., Jabeen, F., . . . Najam-ul-Haq, M. (2020). Glycosylation heterogeneity and low abundant serum glycoproteins MS analysis by boronic acid immobilized Fe<inf>3</inf>O<inf>4</inf>@1,2-Epoxy-5-Hexene/DVB magnetic core shell nanoparticles. Microchemical Journal, 159, 8 pages.
DOI Scopus7 WoS8
2020 Stevens, K. G., & Pukala, T. L. (2020). Conjugating immunoassays to mass spectrometry: solutions to contemporary challenges in clinical diagnostics.. Trends Analyt Chem, 132, 1-10.
DOI Scopus29 WoS23 Europe PMC13
2020 Sajid, M. S., Jovcevski, B., Pukala, T. L., Jabeen, F., & Najam-Ul-Haq, M. (2020). Fabrication of Piperazine Functionalized Polymeric Monolithic Tip for Rapid Enrichment of Glycopeptides/Glycans.. Anal Chem, 92(1), 683-689.
DOI Scopus16 WoS15 Europe PMC10
2020 Sanders, H. M., Jovcevski, B., Carver, J., & Pukala, T. L. (2020). The molecular chaperone β-casein prevents amorphous and fibrillar aggregation of α-lactalbumin by stabilisation of dynamic disorder. Biochemical Journal, 477(3), 629-643.
DOI Scopus23 WoS22 Europe PMC15
2020 Wang, C. R., Bubner, E. R., Jovcevski, B., Mittal, P., & Pukala, T. L. (2020). Interrogating the higher order structures of snake venom proteins using an integrated mass spectrometric approach.. J Proteomics, 216, 103680.
DOI Scopus21 WoS20 Europe PMC19
2020 Hayes, A. J., Satiaputra, J., Sternicki, L. M., Paparella, A. S., Feng, Z., Lee, K. J., . . . Polyak, S. W. (2020). Advanced resistance studies identify two discrete mechanisms in staphylococcus aureus to overcome antibacterial compounds that target biotin protein ligase. Antibiotics, 9(4), 1-20.
DOI Scopus6 WoS6 Europe PMC4
2019 Liu, Y., Jovcevski, B., & Pukala, T. L. (2019). C-Phycocyanin from Spirulina Inhibits α-synuclein and amyloid-β fibril formation but not amorphous aggregation. Journal of Natural Products, 82(1), 66-73.
DOI Scopus32 WoS29 Europe PMC19
2019 Satiaputra, J., Sternicki, L. M., Hayes, A. J., Pukala, T. L., Booker, G. W., Shearwin, K. E., & Polyak, S. W. (2019). Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureus. Scientific Reports, 9(1), 2767-1-2767-13.
DOI Scopus6 WoS5 Europe PMC5
2019 Alcock, L. J., Oliveira, B. L., Deery, M. J., Pukala, T. L., Perkins, M. V., Bernardes, G. J. L., & Chalker, J. M. (2019). Norbornene probes for the detection of cysteine sulfenic acid in cells. ACS chemical biology, 14(4), 594-598.
DOI Scopus36 WoS37 Europe PMC25
2019 Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P., Bernfur, K., . . . Sinz, A. (2019). First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study. Analytical Chemistry, 91(11), 6953-6961.
DOI Scopus104 WoS101 Europe PMC102
2019 Aung, T. N., Nourmohammadi, S., Qu, Z., Harata-Lee, Y., Cui, J., Shen, H. Y., . . . Adelson, D. L. (2019). Fractional deletion of Compound Kushen Injection indicates cytokine signaling pathways are critical for its perturbation of the cell cycle. Scientific Reports, 9(1), 14200-1-14200-16.
DOI Scopus12 WoS10 Europe PMC13
2019 Li, J., Begbie, A., Boehm, B. J., Button, A., Whidborne, C., Pouferis, Y., . . . Pukala, T. L. (2019). Ion mobility-mass spectrometry reveals details of formation and structure for GAA·TCC DNA and RNA triplexes. Journal of the American Society for Mass Spectrometry, 30(1), 103-112.
DOI Scopus18 WoS19 Europe PMC13
2019 Harrison, J. A., Kelso, C., Pukala, T. L., & Beck, J. L. (2019). Conditions for analysis of native protein structures using uniform field drift tube ion mobility mass spectrometry and characterization of stable calibrants for TWIM-MS. Journal of The American Society for Mass Spectrometry, 30(2), 256-267.
DOI Scopus27 WoS30 Europe PMC21
2018 Child, S. A., Bradley, J. M., Pukala, T. L., Svistunenko, D. A., Le Brun, N. E., & Bell, S. G. (2018). Electron transfer ferredoxins with unusual cluster binding motifs support secondary metabolism in many bacteria. Chemical Science, 9(41), 7948-7957.
DOI Scopus36 WoS35 Europe PMC24
2018 Alcock, L., Farrell, K., Akol, M., Jones, G., Tierney, M., Kramer, H., . . . Chalker, J. (2018). Norbornene probes for the study of cysteine oxidation. Tetrahedron, 74(12), 1220-1228.
DOI Scopus33 WoS33
2018 Boehm, B., Whidborne, C., Button, A., Pukala, T., & Huang, D. (2018). DNA triplex structure, thermodynamics, and destabilisation: insight from molecular simulations. Physical Chemistry Chemical Physics, 20(20), 14013-14023.
DOI Scopus17 WoS16 Europe PMC10
2018 Das, S., Pukala, T., & Smid, S. (2018). Exploring the structural diversity in inhibitors of α-Synuclein amyloidogenic folding, aggregation, and neurotoxicity. Frontiers in Chemistry, 6(MAY), 181-1-181-12.
DOI Scopus25 WoS26 Europe PMC16
2018 Young, T., Pukala, T., Cappai, R., Wedd, A., & Xiao, Z. (2018). The human amyloid precursor protein binds copper ions dominated by picomolar-affinity site in the helix-rich E2 domain. Biochemistry, 57(28), 4165-4176.
DOI Scopus24 WoS23 Europe PMC19
2018 Frkic, R. L., Marshall, A. C., Blayo, A. -L., Pukala, T. L., Kamenecka, T. M., Griffin, P. R., & Bruning, J. B. (2018). PPARγ in complex with an antagonist and inverse agonist: a tumble and trap mechanism of the activation helix. iScience, 5, 69-79.
DOI Scopus59 WoS56 Europe PMC49
2018 Pukala, T. (2018). Importance of collision cross section measurements by ion mobility-mass spectrometry in structural biology. Rapid communications in mass spectrometry : RCM, 33(S3), 1-10.
DOI Scopus27 WoS27 Europe PMC17
2016 Calabrese, A., Liu, Y., Wang, T., Musgrave, I., Pukala, T., Tabor, R., . . . Bowie, J. (2016). The amyloid fibril-forming properties of the amphibian antimicrobial peptide uperin 3.5. ChemBioChem, 17(3), 239-246.
DOI Scopus45 WoS44 Europe PMC34
2016 Das, S., Stark, L., Musgrave, I., Pukala, T., & Smid, S. (2016). Bioactive polyphenol interactions with β amyloid: a comparison of binding modelling, effects on fibril and aggregate formation and neuroprotective capacity. Food & Function, 7(2), 1138-1146.
DOI Scopus50 WoS45 Europe PMC27
2015 Liu, Y., Graetz, M., Ho, L., & Pukala, T. (2015). Ion mobility-mass spectrometry-based screening for inhibition of α-synuclein aggregation. European Journal of Mass Spectrometry, 21(3), 255-264.
DOI Scopus15 WoS15 Europe PMC12
2015 Calabrese, A., Bowie, J., & Pukala, T. (2015). Structural Analysis of Calmodulin Binding by nNOS Inhibitory Amphibian Peptides. Biochemistry, 54(2), 567-576.
DOI Scopus8 WoS8 Europe PMC8
2014 Liu, Y., Carver, J., Calabrese, A., & Pukala, T. (2014). Gallic acid interacts with α-synuclein to prevent the structural collapse necessary for its aggregation. Biochimica et Biophysica Acta, 1844(9), 1481-1485.
DOI Scopus102 WoS100 Europe PMC70
2014 Liu, Y., Carver, J., Ho, L., Elias, A., Musgrave, I., & Pukala, T. (2014). Hemin as a generic and potent protein misfolding inhibitor. Biochemical and Biophysical Research Communications, 454(2), 295-300.
DOI Scopus24 WoS24 Europe PMC19
2013 Liu, Y., Pukala, T., Musgrave, I., Williams, D., Dehle, F., & Carver, J. (2013). Gallic acid is the major component of grape seed extract that inhibits amyloid fibril formation. Bioorganic & Medicinal Chemistry Letters, 23(23), 6336-6340.
DOI Scopus112 WoS108 Europe PMC69
2013 Calabrese, A., & Pukala, T. (2013). Chemical cross-linking and mass spectrometry for the structural analysis of protein assemblies. Australian Journal of Chemistry, 66(7), 749-759.
DOI Scopus15 WoS15
2013 Cottam, J., Scanlon, D., Karas, J., Calabrese, A., Pukala, T., Forbes, B., . . . Abell, A. (2013). Chemical synthesis of a fluorescent IGF-II analogue. International Journal of Peptide Research and Therapeutics, 19(1), 61-69.
DOI Scopus5 WoS4
2013 Williams, D., & Pukala, T. (2013). Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry. Mass Spectrometry Reviews, 32(3), 169-187.
DOI Scopus36 WoS34 Europe PMC30
2013 Scott, D., Ehebauer, M., Pukala, T., Marsh, M., Blundell, T., Venkitaraman, A., . . . Hyvonen, M. (2013). Using a fragment-based approach to target protein-protein interactions. ChemBioChem, 14(3), 332-342.
DOI Scopus113 WoS102 Europe PMC81
2013 Calabrese, A., Wang, T., Bowie, J., & Pukala, T. (2013). Negative ion fragmentations of disulfide-containing cross-linking reagents are competitive with aspartic acid side-chain-induced cleavages. Rapid Communications in Mass Spectrometry, 27(1), 238-248.
DOI Scopus6 WoS6 Europe PMC3
2012 Calabrese, A., Good, N., Wang, T., He, J., Bowie, J., & Pukala, T. (2012). A negative ion mass spectrometry approach to identify cross-linked peptides utilizing characteristic disulfide fragmentations. Journal of the American Society for Mass Spectrometry, 23(8), 1364-1375.
DOI Scopus15 WoS15 Europe PMC10
2012 Calabrese, A., Speechley, L., & Pukala, T. (2012). Characterisation of calmodulin structural transitions by ion mobility mass spectrometry. Australian Journal of Chemistry, 65(5), 504-511.
DOI Scopus9 WoS9
2012 Leung, H., Mohan, P., Pukala, T., Scanlon, D., Lincoln, S., & Kee, T. (2012). Reduction of Copper(II) to Copper(I) in the Copper-Curcumin Complex Induces Decomposition of Curcumin. Australian Journal of Chemistry, 65(5), 490-495.
DOI Scopus6 WoS6
2012 McColl, G., Roberts, B., Pukala, T., Kenche, V., Roberts, C., Link, C., . . . Cherny, R. (2012). Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease. Molecular Neurodegeneration, 7(1), 1-9.
DOI Scopus203 WoS188 Europe PMC179
2011 Pukala, T. (2011). Mass spectrometry for structural biology: determining the composition and architecture of protein complexes. Australian Journal of Chemistry, 64(6), 681-691.
DOI Scopus5 WoS5
2011 Wang, T., Andreazza, H., Pukala, T., Sherman, P., Calabrese, A., & Bowie, J. (2011). Histidine-containing host-defence skin peptides of anurans bind Cu²⁺. An electrospray ionisation mass spectrometry and computational modelling study. Rapid Communications in Mass Spectrometry, 25(9), 1209-1221.
DOI Scopus7 WoS7 Europe PMC4
2011 Sanchez, L., Madurga, S., Pukala, T., Vilaseca, M., Lopez-Iglesias, C., Robinson, C., . . . Carulla, N. (2011). Aβ40 and Aβ42 amyloid fibrils exhibit distinct molecular recycling. Journal of the American Chemical Society, 133(17), 6505-6508.
DOI Scopus100 WoS97 Europe PMC85
2011 Jackway, R., Pukala, T., Donnellan, S., Sherman, P., Tyler, M., & Bowie, J. (2011). Skin peptide and cDNA profiling of Australian anurans: Genus and species identification and evolutionary trends. Peptides, 32(1), 161-172.
DOI Scopus22 WoS19 Europe PMC17
2011 Liu, Y., Ho, L., Carver, J., & Pukala, T. (2011). Ion mobility mass spectrometry studies of the inhibition of alpha synuclein amyloid fibril formation by (-)-epigallocatechin-3-gallate. Australian Journal of Chemistry, 64(1), 36-40.
DOI Scopus20 WoS20
2009 Pukala, T., Ruotolo, B., Zhou, M., Politis, A., Stefanescu, R., Leary, J., & Robinson, C. (2009). Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements. Structure, 17(9), 1235-1243.
DOI Scopus99 WoS96 Europe PMC80
2008 Pukala, T., Urathamakul, T., Watt, S., Beck, J., Jackway, R., & Bowie, J. (2008). Binding studies of nNOS-active amphibian peptides and Ca²⁺ calmodulin, using negative ion electrospray ionisation mass spectrometry. Rapid Communications in Mass Spectrometry, 22(22), 3501-3509.
DOI Scopus13 WoS13 Europe PMC8
2008 Jackway, R., Pukala, T., Maselli, V., Musgrave, I., Bowie, J., Liu, Y., . . . Tyler, M. (2008). Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: Structure, activity and evolutionary trends. Regulatory Peptides, 151(1-3), 80-87.
DOI Scopus10 WoS10 Europe PMC8
2008 Gehman, J., Luc, F., Hall, K., Lee, T., Boland, M., Pukala, T., . . . Separovic, F. (2008). Effect of antimicrobial peptides from Australian tree frogs on anionic phospholipid membranes. Biochemistry, 47(33), 8557-8565.
DOI Scopus77 WoS79 Europe PMC59
2007 Pukala, T., Boland, M., Gehman, J., Kuhn-Nentwig, L., Separovic, F., & Bowie, J. (2007). Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers. Biochemistry, 46(11), 3576-3585.
DOI Scopus42 WoS43 Europe PMC35
2007 Pukala, T., Doyle, J., Llewellyn, L., Kuhn-Nentwig, L., Sorrell, M., Separovic, F., & Bowie, J. (2007). Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase. FEBS Journal, 274(7), 1778-1784.
DOI Scopus18 WoS17 Europe PMC12
2006 Pukala, T., Bertozzi, T., Donnellan, S., Bowie, J., Surinya, K., Liu, Y., . . . Tyler, M. (2006). Host-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea. FEBS Journal, 273(15), 3511-3519.
DOI Scopus25 WoS27 Europe PMC21
2006 Pukala, T., Bowie, J., Maselli, V., Musgrave, I., & Tyler, M. (2006). Host-defence peptides from the glandular secretions of amphibians: structure and activity. Natural Product Reports, 23(3), 368-393.
DOI Scopus184 WoS177 Europe PMC139
2004 Sorrell, M., Pukala, T., Brinkworth, C., Maselli, V., Bowie, J., Tyler, M., . . . Llewellyn, L. (2004). Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides, 25(6), 1035-1054.
DOI Scopus211 WoS202 Europe PMC136
2004 Brinkworth, C., Pukala, T., Bowie, J., & Tyler, M. (2004). Host defence peptides from the skin glands of Australian amphibians. Caerulein neuropeptides and antimicrobial, anticancer, and nNOS inhibiting citropins from the glandular frog Litoria subglandulosa.. Australian Journal of Chemistry, 57(7), 693-701.
DOI Scopus5 WoS6
2004 Pukala, T., Brinkworth, C., Carver, J., & Bowie, J. (2004). Investigating the importance of the flexible hinge in caerin 1.1: Solution structures and activity of two synthetically modified caerin peptides. Biochemistry, 43(4), 937-944.
DOI Scopus66 WoS66 Europe PMC46

Year Citation
2023 Nguyen, S., Jovcevski, B., Truong, J. Q., Pukala, T. L., & Bruning, J. B. (2023). A structural model of the human plasminogen and <i>Aspergillus fumigatus</i> enolase complex: insights for antifungal drug discovery. In ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES Vol. 79 (pp. C706). INT UNION CRYSTALLOGRAPHY.
2015 Smid, S., Das, S., Musgrave, I., & Pukala, T. (2015). Bioactive polyphenol interactions with β amyloid: a comparison of binding, fibril inhibition and neuroprotection. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 363-364). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2008 Sanchez-Torner, L., Pukala, T., Vilaseca, M., Robinson, C., Giralt, E., & Carulla, N. (2008). Recycling in Aβ(1-42) amyloid fibrils. In JOURNAL OF PEPTIDE SCIENCE Vol. 14 (pp. 108). WILEY.
2008 Sanchez, L., Pukala, T., Zhou, M., Vilaseca, M., Carulla, N. L., & Giralt, E. (2008). Structure and dynamic characterization of βA aggregates using HID exchange experiments by mass spectrometry. In JOURNAL OF PEPTIDE SCIENCE Vol. 14 (pp. 110). WILEY.
2007 Gehman, J. D., Boland, M. P., Pukala, T. L., Bowie, J. H., & Separovic, F. (2007). Membrane interactions of antimicrobial peptides from Australian tree frogs.. In BIOPHYSICAL JOURNAL (pp. 70A). Baltimore, MD: BIOPHYSICAL SOCIETY.

Year Citation
2021 Hull, A., Li, Y., Hsieh, W., Staudacher, A., Pukala, T., Tieu, W., . . . Bezak, E. (2021). RADIOIMMUNOCONJUGATE DEVELOPMENT: PRELIMINARY TESTING OF A C595 BASED IMMUNOCONJUGATE. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY.
2019 Pukala, T., Begbie, A., & Li, J. (2019). Ion mobility mass spectrometry to characterize formation and structure of DNA assemblies. Poster session presented at the meeting of ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. San Diego, CA: AMER CHEMICAL SOC.

Year Citation
2025 Rusli, O., Wang, R., Pachulicz, R. J., Zenaidee, M. A., Pukala, T. L., Ucur, B., . . . Rijs, N. J. (2025). Cross-Platform Ion Mobility-Mass Spectrometry of Cationized Imidacloprid and Chlorpyrifos.
DOI
2025 Rusli, O., Wang, R., Pachulicz, R. J., Zenaidee, M. A., Pukala, T. L., Ucur, B., . . . Rijs, N. J. (2025). Cationized Imidacloprid and Chlorpyrifos via Cross-Platform Ion Mobility-Mass Spectrometry.
DOI

Australian Research Council Projects

2024-26: ARC Linkage Project (LP230100307)

D Adelson, T Pukala, S Semple, B Simpson, J Conran, D Claudie, W Wang. Finding the targets of natural products in complex botanical extracts, $453K

2020-22:  ARC Discovery Project (DP200102291)

T Pukala Revealing molecular detail of DNA triplexes to underpin antigene technology, $450K

2018-20:  ARC Discovery Project (DP180103974)

V Bulone and T Pukala.  Characterisation of vital carbohydrate synthases in pathogenic oomycetes, $546K 

2017-19:  ARC Discovery Project (DP170102033)

T Pukala and A Politis. Mass spectrometry to reveal the role of lipids in protein misfolding, $324K

2011-13:  ARC Discovery Project (DP110100496)

T Pukala. Structural and functional investigations of the human transcription machinery by ion mobility mass spectrometry, $340K

2010-12:  ARC Discovery Project (DP1093143)

T Pukala and J Bowie. Novel mass spectrometric approaches to the study of protein-protein interactions, $360K

Equipment

2024: ARC LIEF (LE240100135)

T Pukala, P Hoffmann, M Herderich, M Snel, E Watson, K Shearwin, S Gaskin, N Lloyd, P Trim, G Goodall. An ion mobility-mass spectrometry based platform for structural proteomics, $880K

2020:  ARC LIEF (LE200100183)

P Hoffmann, T Chataway, T Pukala, M Herderich, E Hilder, D Keating, K Kirkbride, S Plush, S Pitson, C Proud, D Brooks.  Protein Quantitation Centre of South Australia renewal for Systems Biology, $950K

2013:  ARC LIEF (LE130100199)

P Hoffmann, T Chataway, J Bowie, G Fincher, M Brown, T Pukala, C Franco, D Keating, D Brooks, L Cosgrove, K Fung, M Herderich, W Hines.  Establishment of the peptide and protein quantitation centre of South Australia: PAPQuaC-SA, $475K

2012:  ARC LIEF (LE120100181)

L Botten, D Leinweber, L Radom, J Gready, M England, A Mark, H Blackburn, A Hogg, C Jakob, A Pitman, BJ Powell, K Rasmussen, L Moresi, A Yu, M Knackstedt, M Bilek, M Ragan, B Schmidt, R Muller, T Pukala, J Sori, C Turney, K Hourigan, D Adelson, R Khanna, J Denier, B Pailthorpe. Strengthened merit-based access and support at the new NCI petascale supercomputing facility, $650K

Other

2022: AWRI-UA Collaborative Research Investment Fund

Pukala T, Herderich M.  A cyclic ion-mobility mass spectrometer and platform technologies for structural proteomics, $50K

2019-2022: Department of Industry and Skills Research Consortia Program (FND000639)

Bulone V, Pukala T, Abell A, Zannettino A, Beattie D, Krasowska M, Zhou Q, Koltunow A. Research Consortium Program for Agricultural Product Development, $4M

2021-2022: Worksafe BC Specific Priorities/Systematic Reviews Grant Program

Gaskin S, Pukala T, Thredgold L.  Developing a measurement method to determine the Threshold Limit Value-Surface Limit concentration of o-phthalaldehyde, $75K (CAD)

2016-2018:  The Australia & Pacific Science Foundation

S Petit, T Pukala, R Schumann, A Naikatini, A Scanlon. Unique pollination system of an important rainforest tree involving obligate manipulation by bats, $45K



2016-17: University of Adelaide Interdisciplinary Research Fund

V Bulone, T Pukala, A Zannettino, C Doonan, C Sumby. An interdisciplinary research program to map the protein-glycan interactome of key eukaryotic cellular systems: interfacing biophysics and chemistry with cancer research, microbiology and plant sciences, $25K

2016: University of Adelaide Faculty of Sciences eLearning Program

NM Williamson, TL Pukala, CJ Doonan.  Development of level II chemistry online assessment and student feedback. $7K

2013-14: University of Adelaide Interdisciplinary Research Fund

I Musgrave, S Smid, L O’Keefe, T Pukala. Structure function relationships of antiamyloid drugs: verification in an in-vivo model, $21K



2013-14: University of Adelaide Interdisciplinary Research Fund

T Pukala and M Fuller. Mass spectrometric approaches to characterise alpha-synuclein-glucosylsphingosine interations: application to the Parkinsonian Syndrome, $25K

Teaching interests include:

Biological structure determination

Mass spectrometry and NMR spectroscopy

Biological and synthetic organic chemistry

Physical organic chemistry

Foundations of chemistry

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Characterisation and Profiling of Bioactive Molecules from Food Waste as Inhibitors of Protein Aggregation in Motor Neuron Disease Master of Philosophy Master Full Time Miss Rebekah Grace Munro
2025 Co-Supervisor The analysis of mouse and human models of clozapine related adverse effects Doctor of Philosophy Doctorate Full Time Miss Noor Ul Ain
2024 Co-Supervisor Tantalum-Based Metal Oxides for the Photocatalytic Degradation of Per- or Polyfluoroalkyl Substances (PFAS) Doctor of Philosophy Doctorate Full Time Miss Rachael Kate Matthews
2024 Co-Supervisor In vitro neuroprotective effects of alpha-1 adrenoceptor antagonists Doctor of Philosophy Doctorate Full Time Mr Aari Jasper Oliphant-Hand
2024 Co-Supervisor Development of a novel method for the solution-phase synthesis of sequence-defined polymers with potential biomimetic application Doctor of Philosophy Doctorate Full Time Ms Rachel Josephine Tishler
2024 Principal Supervisor Investigating links between lipid metabolism and protein post-translational modifications in Alzheimer's disease Doctor of Philosophy Doctorate Full Time Mrs Elaheh Eskandari
2024 Principal Supervisor Mass spectrometry method development for the analysis of intact proteins Doctor of Philosophy Doctorate Full Time Mr Shaun Thomas Ellis
2024 Co-Supervisor Diagnosis and Treatment of Clozapine Associated Adverse Events and their Association with Inflammation Doctor of Philosophy Doctorate Full Time Mr Wei Ching Shawn Yong
2024 Principal Supervisor Mass spectrometry Approaches to Analysis Intact Protein Assemblies in the context of protein-misfolding disorders Doctor of Philosophy Doctorate Full Time Ms Shima Amini
2023 Co-Supervisor Identification and Exploitation of Carbohydrate Polymers and Bioactive Compounds from Plant Biomass Doctor of Philosophy Doctorate Full Time Mr David Nkurunziza
2023 Principal Supervisor Fundamental understanding of DNA triplex formation and its antigene properties to control gene expression Doctor of Philosophy Doctorate Full Time Miss Sarveenah RGChandrasegaran
2023 Co-Supervisor Development of protein biomarker assays for Alzheimer's disease Doctor of Philosophy Doctorate Full Time Mr Nicholas Ronan John Graham
2022 Principal Supervisor Diagnosis and therapeutics of intrinsically disordered protein misfolding disorders Doctor of Philosophy Doctorate Full Time Mr Zohaib Raza
2022 Principal Supervisor Characterisation and design of DNA-binding oligonucleotides: A concerted experimental and computational investigation. Doctor of Philosophy Doctorate Full Time Mr Gerardo Urbina
2021 Principal Supervisor Characterisation of Snake Venom Proteins to Inform New Advances in Biotechnology Doctor of Philosophy Doctorate Part Time Mr Lewis Owen McFarlane

Date Role Research Topic Program Degree Type Student Load Student Name
2021 - 2025 Principal Supervisor Development of novel mass spectrometry methods for phosphorylated protein analysis Doctor of Philosophy Doctorate Full Time Miss Siqi Li
2021 - 2024 Principal Supervisor Mass spectrometry-based approaches towards characterising anthocyanin structures in plant extracts Doctor of Philosophy Doctorate Full Time Dr River Jack Pachulicz
2021 - 2024 Principal Supervisor Development of Mass Spectrometric-Immunoassays for the Detection of Neurodegenerative Disease Biomarkers Master of Philosophy Master Full Time Mr Shaun Thomas Ellis
2020 - 2024 Principal Supervisor Structural Characterisation of Snake Venom Proteins by Mass Spectrometry Doctor of Philosophy Doctorate Full Time Miss Chia-De Ruth Wang
2020 - 2024 Principal Supervisor Biophysical characterisation of DNA triplexes for antigene applications Doctor of Philosophy Doctorate Full Time Mr Jack William Klose
2019 - 2021 Principal Supervisor Mass Spectrometric Characterisation of Protein Assemblies from Bitis arietans Snake Venom Master of Philosophy Master Full Time Miss Emily Rose Bubner
2019 - 2023 Co-Supervisor Identification of human biomarkers in saliva for early detection of Alzheimer's disease and other dementia related illnesses Doctor of Philosophy Doctorate Full Time Ms Kym McNicholas
2018 - 2020 Principal Supervisor Structural Investigation of Snake Venom Proteins by Mass Spectrometry Master of Philosophy Master Full Time Miss Chia-De Ruth Wang
2017 - 2021 Principal Supervisor Mass Spectrometric Methods for the Analysis of Chemically Modified Proteins Doctor of Philosophy Doctorate Full Time Miss Katherine Stevens
2017 - 2022 Principal Supervisor A Biophysical Investigation of Nucleic Acid Triplexes and Inversion Site Recognising Analogues Doctor of Philosophy Doctorate Part Time Mr Alexander Jacob Begbie
2016 - 2021 Principal Supervisor MASS SPECTROMETRY-BASED STRUCTURAL INSIGHTS INTO PROTEIN ASSEMBLIES Doctor of Philosophy Doctorate Part Time Mr Henry Michael Sanders
2016 - 2018 Co-Supervisor A Mechanistic Study of the Stability of Triple-Stranded DNA Structures Master of Philosophy Master Full Time Mrs Belinda Jayne Boehm
2015 - 2018 Co-Supervisor Small molecular inhibitors of Amyloid beta and alpha Synuclein amyloidogenic aggregation, toxicity and in silico design of amyloid-binding ligands Doctor of Philosophy Doctorate Full Time Mrs Sukanya Das
2014 - 2017 Principal Supervisor Design and Synthesis of Protein Chemical Crosslinkers: A Modular Approach Master of Philosophy Master Full Time Miss Kayla Monique Downey
2012 - 2018 Principal Supervisor Biological and Structure Characterisation of Eukaryotic Prefoldin Doctor of Philosophy Doctorate Full Time Denise Tran
2011 - 2019 Co-Supervisor Application of Synchrotron-Based Spectroscopic Techniques XAS and XFM towards Probing the Cellular Metallome Doctor of Philosophy Doctorate Full Time Mr Jason Lee Wedding
2010 - 2014 Co-Supervisor Structural and mechanistic studies of post-translationally modified peptides and proteins Doctor of Philosophy Doctorate Full Time Miss Thi Thanh Nha Tran
2009 - 2013 Co-Supervisor Characterisation of Protein Structure and Interactions: Novel Applications to the Study of Bioactive Peptides Doctor of Philosophy Doctorate Full Time Antonio Calabrese
2009 - 2014 Co-Supervisor Linked beta-cyclodextrin trimers: From molecular recognition to polymer network hydrogels Doctor of Philosophy Doctorate Full Time Mrs Trang Thi Hanh Nguyen
2009 - 2014 Co-Supervisor A study on the interactions of synthetic IGF-II analogues with the type 1 IGF and insulin receptors Doctor of Philosophy Doctorate Part Time Miss Jade Misty Cottam

Date Role Committee Institution Country
2011 - ongoing Member Australian and New Zealand Society for Mass Spectrometry Executive Committee Australian and New Zealand Society for Mass Spectrometry Australia

Date Role Membership Country
2009 - ongoing Member Australian Society for Biophysics Australia
2005 - ongoing Member Royal Australian Chemical Institute Australia
2004 - ongoing - Australian and New Zealand Society for Mass Spectrometry Australia

Date Role Editorial Board Name Institution Country
2024 - ongoing Board Member International Journal of Mass Spectrometry Elsevier Netherlands
2019 - ongoing Board Member Analytical Chemistry ACS Publications United States
2017 - ongoing Associate Editor Frontiers in Chemistry (Medicinal and Pharmaceutical Chemistry) Frontiers Switzerland
2017 - ongoing Associate Editor Rapid Communications in Mass Spectrometry Wiley United States
2017 - ongoing Editor European Journal of Mass Spectrometry SAGE Journals United Kingdom
2013 - ongoing Board Member Nature Scientific Reports Nature Publishing Group United States

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