Associate Professor Kylie Dunning

Ext-Funded Research Fellow (D)

Robinson Research Institute

Division of Research and Innovation

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Associate Professor Kylie Dunning leads the Reproductive Success team within the Robinson Research Institute, the Institute for Photonics and Advanced Sensing, and the School of Biomedicine.

Kylie is a reproductive biologist who uses cutting-edge, light-based technologies (also referred to as photonics) to better understand the biology that underpins successful development of the oocyte (egg) and early embryo. With one-in-six Australian couples struggling to start a family without medical intervention, Kylie is committed turning her laboratory discoveries into impact for these couples, engaging early and often with clinical experts to address the greatest clinical challenges.

With a focus on how oocytes (eggs) and embryos create energy, Kylie pioneered the paradigm-shifting research describing the requirement for lipid metabolism by the oocyte and early embryo.

With a drive to see outcomes for patients, Kylie is now using this knowledge and expertise with cutting-edge imaging and diagnostic technologies, to deliver the next generation of tools for the fertility clinic, and agriculture industry. She is leading the way in the development of safe, non-invasive diagnostic technologies that will change the way fertility specialists and embryologists select the best eggs and embryos, which will ultimately improve the experience for all couples seeking fertility care.

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Professional Activities
Contact

Research Interests

In our team we use safe, cutting-edge, light-based technologies (also referred to as photonics) to better understand the biology that underpins successful development of the oocyte (egg) and early embryo. With one-in-six Australian couples struggling to start a family without medical intervention, we are committed turning our laboratory discoveries into impact for these couples, engaging early and often with clinical experts to address the greatest clinical challenges.

Research Team

We have a culturally and gender diverse team who are supportive and encouraging of each other. Our team consists of four post-doctoral researchers (Dr Megan Lim, Dr Tiffany Tan, Dr Avinash Upadhya and Dr Darren Chow), five post-graduate (Carl Campugan, Annie Whitty, Tong Li, Shan Li and Ramses Bautista Gonzalez) and one Honours students (Wenyu Li).

Current Projects

Title: Novel optical assessments of embryo development: can we pick the best embryo?

Project description: Increasingly, people are delaying starting a family until later in life. The expectation of conceiving children is often disrupted by infertility (1 in 6 Australian couples). Such a diagnosis can lead to reduced productivity, financial hardship, relationship breakdown and mental illness. Infertility is typically addressed by in vitro fertilization (IVF). Whilst IVF has seen major advancements, it still faces numerous challenges, most notably low success rates: only 18% of Australian and New Zealand initiated IVF cycles deliver a live birth. One of the reasons for the low success rate is the inability to select the healthiest embryo. In this project you will utilise cutting edge microscopy techniques combined with post-imaging assessments to better understand the pre-implantation embryo development period. You will be comparing normal healthy embryos with poor quality embryos: those which fail to complete the preimplantation period or lead to implantation failure or pregnancy loss. Our research is clinically relevant, and we are passionate about translating outcomes into the human IVF clinic and in agriculture. Don’t hesitate to contact us to discuss further.

Projects available for: Third Year / Honours / HDR

Location: Helen Mayo Building

Research project start: Semester 1 and 2

Special requirements: N/A

Appointments

Date	Position	Institution name
2023 - ongoing	Future Making Fellow	University of Adelaide
2021 - ongoing	Director	IVF Vet Solutions
2020 - ongoing	Chief Investigator	ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP)
2020 - 2023	The Hospital Research Foundation Fellow	University of Adelaide
2017 - 2019	ARC Senior Research Associate	University of Adelaide
2012 - 2017	ARC DECRA Fellow	University of Adelaide
2007 - 2011	NHMRC Research Associate	University of Adelaide, Adelaide
2002 - 2003	Research Assistant	Women's and Children's Hospital, Adelaide

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2022	Award	Rising Star Award	Society for the Study of Reproduction	United States	-
2020	Award	Women's Excellence in Research Award	Healthy Development Adelaide	Australia	-
2020	Award	Robinson Research Institute Directors Award	The Robinson Research Institute	Australia	-
2020	Award	South Australian Tall Poppy of the Year (overall winner)	Australian Institute for Policy and Science	Australia	-
2019	Award	Newcastle Reproduction Emerging Research Leader Award	Society for Reproductive Biology	Australia	-
2012	Award	Most Outstanding Early Career Researcher	Discipline of Obstetrics and Gynaecology, The University of Adelaide	-	$3000
2010	Award	First Place, Trainee Research Award	Society for the Study of Reproduction	United States	-
2010	Award	First place, Young Investigator Award	Women's and Children's Hospital	Australia	$10,000
2010	Award	Lalor Foundation Merit Award	Lalor Foundation, Society for the Study of Reproduction	United States	-
2007	Award	Robert Seamark Postgraduate Award	University of Adelaide	Australia	-
2007	Award	National Research Initiative (NRI) Merit Award	United States Department of Agriculture, CSREES	United States	-

Language Competencies

Language Competency

English Can read, write, speak, understand spoken and peer review

Language	Competency
English	Can read, write, speak, understand spoken and peer review

Education

Date	Institution name	Country	Title
2008	University of Adelaide, Adelaide	Australia	Doctor of Philosophy
2002	University of Adelaide, Adelaide	Australia	Bachelor of Science (Honours)
2001	University of Adelaide, Adelaide	Australia	Bachelor of Science

Research Interests

Animal developmental and reproductive biology Cell Metabolism Fertility Paediatrics and Reproductive Medicine Reproduction Reproductive Biology Reproductive medicine

Journals

Year	Citation
2024	Chow, D. J. X., Schartner, E. P., Corsetti, S., Upadhya, A., Morizet, J., Gunn-Moore, F. J., . . . Dholakia, K. (2024). Quantifying DNA damage following light sheet and confocal imaging of the mammalian embryo. Scientific Reports, 14(1), 20760-1-20760-12. DOI
2024	McLennan, H. J., Heinrich, S. L., Inge, M. P., Wallace, S. J., Blanch, A. J., Hails, L., . . . Love, A. K. (2024). A micro-fabricated device (microICSI) improves porcine blastocyst development and procedural efficiency for both porcine intracytoplasmic sperm injection and human microinjection. Journal of Assisted Reproduction and Genetics, 41(2), 297-309. DOI Scopus1
2024	Lee, K. J., Trowbridge, A. C., Bruce, G. D., Dwapanyin, G. O., Dunning, K. R., Dholakia, K., & Schartner, E. P. (2024). Learning algorithms for identification of whisky using portable Raman spectroscopy. Current Research in Food Science, 8, 100729-1-100729-10. DOI
2024	Chow, D. J. X., Tan, T. C. Y., Upadhya, A., Lim, M., Dholakia, K., & Dunning, K. R. (2024). Viewing early life without labels: optical approaches for imaging the early embryo†. Biology of Reproduction, 110(6), 1157-1174. DOI Scopus2 Europe PMC2
2023	Emery, A., Dunning, K. R., Dinh, D. T., Akison, L. K., Robker, R. L., & Russell, D. L. (2023). Dynamic regulation of semaphorin 7A and adhesion receptors in ovarian follicle remodeling and ovulation. Frontiers in Cell and Developmental Biology, 11, 1261038-1-1261038-9. DOI Scopus2 Europe PMC2
2023	Morizet, J., Chow, D., Wijesinghe, P., Schartner, E., Dwapanyin, G., Dubost, N., . . . Dholakia, K. (2023). UVA Hyperspectral Light-Sheet Microscopy for Volumetric Metabolic Imaging: Application to Preimplantation Embryo Development. ACS Photonics, 10(12), 4177-4187. DOI Scopus5 Europe PMC4
2023	McLennan, H. J., Blanch, A. J., Wallace, S. J., Ritter, L. J., Heinrich, S. L., Gardner, D. K., . . . Thompson, J. G. (2023). Nano-liter perfusion microfluidic device made entirely by two-photon polymerization for dynamic cell culture with easy cell recovery. Sci Rep, 13(1), 562-1-562-16. DOI Scopus27 WoS4 Europe PMC5
2023	Dwapanyin, G. O., Chow, D. J. X., Tan, T. C. Y., Dubost, N. S., Morizet, J. M., Dunning, K. R., & Dholakia, K. (2023). Investigation of refractive index dynamics during in vitro embryo development using off-axis digital holographic microscopy. Biomedical Optics Express, 14(7), 3327-3342. DOI Scopus5 Europe PMC5
2022	Capon, P. K., Li, J., Horsfall, A. J., Yagoub, S., Schartner, E. P., Khalid, A., . . . Abell, A. D. (2022). A silk‐based functionalization architecture for single fiber imaging and sensing. Advanced Functional Materials, 32(3), 2010713-1-2010713-11. DOI Scopus7 WoS6
2022	Tan, C., Mahbub, S., Campbell, J., Habibalahi, A., Campugan, C., Rose, R., . . . Dunning, K. (2022). Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo. Human Reproduction, 37(1), 14-29. DOI Scopus24 WoS15 Europe PMC14
2022	Smith, K. M., Dinh, D. T., Akison, L. K., Nicholls, M., Dunning, K. R., Morimoto, A., . . . Robker, R. L. (2022). Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation. Cells, 11(9), 1-23. DOI Scopus6 WoS2 Europe PMC4
2022	Yagoub, S. H., Thompson, J. G., Orth, A., Dholakia, K., Gibson, B. C., & Dunning, K. R. (2022). Fabrication on the microscale: a two-photon polymerized device for oocyte microinjection. Journal of Assisted Reproduction and Genetics, 39(7), 1-11. DOI Scopus9 WoS3 Europe PMC4
2022	Campugan, C. A., Lim, M., Chow, D. J. X., Tan, T. C. Y., Li, T., Saini, A. A., . . . Dunning, K. R. (2022). The effect of discrete wavelengths of visible light on the developing murine embryo. Journal of Assisted Reproduction and Genetics, 39(8), 1825-1837. DOI Scopus7 WoS3 Europe PMC3
2022	Tan, T. C. Y., Brown, H. M., Thompson, J. G., Mustafa, S., & Dunning, K. R. (2022). Optical imaging detects metabolic signatures associated with oocyte quality. Biology of Reproduction, 107(4), 1014-1025. DOI Scopus9 WoS3 Europe PMC4
2022	Yagoub, S. H., Lim, M., Tan, T. C. Y., Chow, D. J. X., Dholakia, K., Gibson, B. C., . . . Dunning, K. R. (2022). Vitrification within a nanoliter volume: oocyte and embryo cryopreservation within a 3D photopolymerized device. Journal of Assisted Reproduction and Genetics, 39(9), 1997-2014. DOI Scopus4 WoS2 Europe PMC3
2022	Tan, T. C. Y., & Dunning, K. R. (2022). Non-invasive assessment of oocyte developmental competence. Reproduction Fertility and Development, 35(1-2), 39-50. DOI Scopus9 WoS2 Europe PMC5
2022	Wijesinghe, P., Corsetti, S., Chow, D. J. X., Sakata, S., Dunning, K. R., & Dholakia, K. (2022). Experimentally unsupervised deconvolution for light-sheet microscopy with propagation-invariant beams.. Light Sci Appl, 11(1), 319. DOI Scopus12 WoS4 Europe PMC5
2021	Richani, D., Dunning, K. R., Thompson, J. G., & Gilchrist, R. B. (2021). Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence. Human Reproduction Update, 27(1), 27-47. DOI Scopus182 WoS94 Europe PMC107
2021	Santos Monteiro, C. A., Chow, D. J. X., Leal, G. R., Tan, C. Y., Reis Ferreira, A. M., Thompson, J. G., & Dunning, K. R. (2021). Optical imaging of cleavage stage bovine embryos using hyperspectral and confocal approaches reveals metabolic differences between on-time and fast-developing embryos. Theriogenology, 159, 60-68. DOI Scopus19 WoS12 Europe PMC8
2021	Lim, M., Thompson, J. G., & Dunning, K. R. (2021). HYPOXIA AND REPRODUCTIVE HEALTH: hypoxia and ovarian function: follicle development, ovulation, oocyte maturation. Reproduction, 161(1), F33-F40. DOI Scopus45 WoS24 Europe PMC25
2021	Lim, M., Brown, H. M., Rose, R. D., Thompson, J. G., & Dunning, K. R. (2021). Dysregulation of bisphosphoglycerate mutase during in vitro maturation of oocytes. Journal of Assisted Reproduction and Genetics, 38(6), 1363-1372. DOI Scopus6 WoS2 Europe PMC4
2021	Whitty, A., Kind, K. L., Dunning, K. R., & Thompson, J. G. (2021). Effect of oxygen and glucose availability during in vitro maturation of bovine oocytes on development and gene expression. Journal of Assisted Reproduction and Genetics, 38(6), 1349-1362. DOI Scopus11 WoS5 Europe PMC3
2021	Chow, D. J. X., Wijesinghe, P., Dholakia, K., & Dunning, K. R. (2021). Does artificial intelligence have a role in the IVF clinic?. Reproduction and Fertility, 2(3), C29-C34. DOI Scopus24 WoS4 Europe PMC13
2020	Campugan, C. A., Dunning, K. R., & Dholakia, K. (2020). Optical manipulation: a step change for biomedical science. Contemporary Physics, 61(4), 1-18. DOI Scopus9 WoS3
2020	Horsfall, A. J., Dunning, K. R., Keeling, K. L., Scanlon, D. B., Wegener, K. L., & Abell, A. D. (2020). A bimane‐based peptide staple for combined helical induction and fluorescent imaging. ChemBioChem, 21(23), 1-11. DOI Scopus9 WoS6 Europe PMC4
2020	McLennan, H. J., Saini, A., Sylvia, G. M., Schartner, E. P., Dunning, K. R., Purdey, M. S., . . . Thompson, J. G. (2020). A biophotonic approach to measure pH in small volumes in vitro: quantifiable differences in metabolic flux around the cumulus-oocyte-complex (COC). Journal of Biophotonics, 13(3), e201960038-1-e201960038-9. DOI Scopus7 WoS7 Europe PMC2
2020	McLennan, H. J., Saini, A., Dunning, K. R., & Thompson, J. G. (2020). Oocyte and embryo evaluation by AI and multi-spectral auto-fluorescence imaging: livestock embryology needs to catch-up to clinical practice. Theriogenology, 150, 255-262. DOI Scopus13 WoS7 Europe PMC7
2019	Kedzior, S., Bianco-Miotto, T., Breen, J., Diener, K. R., Donnelley, M. W., Dunning, K. R., . . . Rumbold, A. R. (2019). It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive. Reproductive Biomedicine and Society Online, 9, 48-63. DOI Scopus10 Europe PMC8
2019	Lim, M., Brown, H. M., Kind, K. L., Breen, J., Anastasi, M. R., Ritter, L. J., . . . Dunning, K. R. (2019). Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression. Reproduction, Fertility and Development, 31(4), 724-734. DOI Scopus7 WoS6 Europe PMC5
2019	Bromfield, E. G., Dowland, S. N., Dunleavy, J. E. M., Dunning, K. R., Holland, O. J., Houston, B. J., . . . Bertoldo, M. J. (2019). Fifty years of reproductive biology in Australia: highlights from the 50th Annual Meeting of the Society for Reproductive Biology (SRB). Reproduction, Fertility and Development, 31(5), 829-836. DOI
2019	Lim, M., Brown, H. M., Kind, K. L., Thompson, J. G., & Dunning, K. R. (2019). Hemoglobin: potential roles in the oocyte and early embryo. Biology of Reproduction, 101(2), 262-270. DOI Scopus9 WoS5 Europe PMC2
2018	Sutherland, J., Frost, E., Ford, E., Peters, A., Reed, N., Seldon, A., . . . McLaughlin, E. (2018). Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary. Molecular Human Reproduction, 24(11), 533-542. DOI Scopus26 WoS20 Europe PMC19
2017	Brown, H., Dunning, K., Sutton-McDowall, M., Gilchrist, R., Thompson, J., & Russell, D. (2017). Failure to launch: aberrant cumulus gene expression during oocyte in vitro maturation. Reproduction, 153(3), R109-R120. DOI Scopus46 WoS39 Europe PMC28
2017	Dunning, K., & Robker, R. (2017). The role of L-carnitine during oocyte in vitro maturation: essential co-factor?. Animal Reproduction, 14(3), 469-475. DOI Scopus15 WoS10
2015	Russell, D., Brown, H., & Dunning, K. (2015). ADAMTS proteases in fertility. Matrix Biology, 44-46, 54-63. DOI Scopus61 WoS49 Europe PMC33
2015	Dunning, K., Watson, L., Zhang, V., Brown, H., Kaczmarek, A., Robker, R., & Russell, D. (2015). Activation of mouse cumulus-oocyte complex maturation in vitro through EGF-like activity of versican. Biology of Reproduction, 92(5), 116-1-116-10. DOI Scopus30 WoS26 Europe PMC20
2015	Hu, F., Dzaye, O., Hahn, A., Yu, Y., Scavetta, R., Dittmar, G., . . . Kettenmann, H. (2015). Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling. Neuro-Oncology, 17(2), 200-210. DOI Scopus130 WoS108 Europe PMC88
2014	Robker, R., Watson, L., Robertson, S., Dunning, K., McLaughlin, E., & Russell, D. (2014). Identification of sites of STAT3 action in the female reproductive tract through conditional gene deletion. PLoS One, 9(7), e101182-1-e101182-9. DOI Scopus27 WoS20 Europe PMC20
2014	Dunning, K., Russell, D., & Robker, R. (2014). Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation. Reproduction, 148(1), R15-R27. DOI Scopus317 WoS228 Europe PMC166
2014	Dunning, K., Anastasi, M., Zhang, V., Russell, D., & Robker, R. (2014). Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by PPAR agonists. PLoS One, 9(2), e87327-1-e87327-11. DOI Scopus118 WoS108 Europe PMC74
2012	Dunning, K., Watson, L., Sharkey, D., Brown, H., Norman, R., Thompson, J., . . . Russell, D. (2012). Molecular filtration properties of the mouse expanded cumulus matrix: controlled supply of metabolites and extracellular signals to cumulus cells and the oocyte. Biology of Reproduction, 87(4), 1-10. DOI Scopus23 WoS23 Europe PMC14
2012	Dunning, K., & Robker, R. (2012). Promoting lipid utilization with l-carnitine to improve oocyte quality. Animal Reproduction Science, 134(1-2), 69-75. DOI Scopus80 WoS66 Europe PMC46
2012	Watson, L., Mottershead, D., Dunning, K., Robker, R., Gilchrist, R., & Russell, D. (2012). Heparan sulfate proteoglycans regulate responses to oocyte paracrine signals in ovarian follicle morphogenesis. Endocrinology, 153(9), 4544-4555. DOI Scopus49 WoS44 Europe PMC34
2012	Akison, L., Alvino, E., Dunning, K., Robker, R., & Russell, D. (2012). Transient invasive migration in mouse cumulus oocyte complexes induced at ovulation by luteinizing hormone. Biology of Reproduction, 86(4), 1-8. DOI Scopus41 WoS33 Europe PMC28
2012	McDowall, M., Inglis, D., Robker, R., Thompson, J., & Dunning, K. (2012). Utilization of endogenous fatty acid stores for energy production in bovine preimplantation embryos. Theriogenology, 77(8), 1632-1641. DOI Scopus97 WoS88 Europe PMC52
2011	Dunning, K., Akison, L., Russell, D., Norman, R., & Robker, R. (2011). Increased beta-oxidation and improved oocyte developmental competence in response to L-Carnitine during ovarian in vitro follicle development in mice. Biology of Reproduction, 85(3), 548-555. DOI Scopus97 WoS84 Europe PMC67
2011	Gebhardt, K., Inglis, D., Dunning, K., Lane, M., & Russell, D. (2011). Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer. Fertility and Sterility, 96(1), 47-54. DOI Scopus163 WoS130 Europe PMC107
2010	Dunning, K., Cashman, K., Russell, D., Thompson, J., Norman, R., & Robker, R. (2010). Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development. Biology of Reproduction, 83(6), 909-918. DOI Scopus343 WoS297 Europe PMC222
2010	Linyan Wu, L., Dunning, K., Yang, X., Russell, D., Lane, M., Norman, R., & Robker, R. (2010). High-fat diet causes lipotoxicity responses in cumulus-oocyte complexes and decreased fertilization rates. Endocrinology, 151(11), 5438-5445. DOI Scopus285 WoS240 Europe PMC183
2010	Yang, X., Dunning, K., Linyan Wu, L., Hickey, T., Norman, R., Russell, D., . . . Robker, R. (2010). Identification of Perilipin-2 as a lipid droplet protein regulated in oocytes during maturation. Reproduction Fertility and Development, 22(8), 1262-1271. DOI Scopus46 WoS43 Europe PMC29
2010	Brown, H., Dunning, K., Robker, R., Boerboom, D., Pritchard, M., Lane, M., & Russell, D. (2010). ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice. Biology of Reproduction, 83(4), 549-557. DOI Scopus131 WoS108 Europe PMC96
2007	Anson, D., McIntyre, C., Thomas, B., Koldej, R., Ranieri, E., Derrick Roberts, A., . . . Byers, S. (2007). Lentiviral-mediated gene correction of mucopolysaccharidosis type IIIA. Genetic Vaccines and Therapy, 5(6), WWW 1-WWW 8. DOI Scopus20 Europe PMC19
2007	Dunning, K., Lane, M., Brown, H., Yeo, C., Robker, R., & Russell, D. (2007). Altered composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes. Human Reproduction, 22(11), 2842-2850. DOI Scopus65 WoS59 Europe PMC45
2007	Kremer, K., Dunning, K., Parsons, D., & Anson, D. (2007). Gene delivery to airway epithetiat cells in vivo: a direct comparison of apicat and basotateral transduction strategies using pseudotyped, lentivirus vectors. Journal of Gene Medicine, 9(5), 362-368. DOI Scopus56 WoS53 Europe PMC50
2006	Brown, H., Dunning, K., Robker, R., Pritchard, M., & Russell, D. (2006). Requirement for ADAMTS-1 in extracellular matrix remodeling during ovarian folliculogenesis and lymphangiogenesis. Developmental Biology, 300(2), 699-709. DOI Scopus103 WoS85 Europe PMC70
2005	Anson, D., & Dunning, K. (2005). Codon-optimized reading frames facilitate high-level expression of the HIV-1 minor proteins. Molecular Biotechnology, 31(1), 85-88. DOI Scopus6 WoS5 Europe PMC5
2004	Hii, C., Anson, D., Costabile, M., Mukaro, V., Dunning, K., & Ferrante, A. (2004). Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response. Journal of Biological Chemistry, 279(48), 49825-49834. DOI Scopus34 WoS32 Europe PMC28

Book Chapters

Year	Citation
2019	Findlay, J. K., Dunning, K. R., Gilchrist, R. B., Hutt, K. J., Russell, D. L., & Walters, K. A. (2019). Follicle Selection in Mammalian Ovaries. In P. Leung, & E. Adashi (Eds.), The Ovary (3 ed., pp. 3-21). United Kingdom: Academic Press. DOI

Conference Papers

Year	Citation
2024	Dunning, K. (2024). Non-invasive evaluation of embryo metabolic activity through hyperspectral microscopy. In HUMAN REPRODUCTION Vol. 39 (pp. 2 pages). NETHERLANDS, Amsterdam: OXFORD UNIV PRESS.
2023	Dwapanyin, G. O., Chow, D. J. X., Tan, T. C. Y., Dubost, N. S., Morizet, J. M., Dunning, K. R., & Dholakia, K. (2023). Digital holographic microscopic assessment of embryo quality. In Frontiers in Optics: Proceedings Frontiers in Optics + Laser Science 2023, FiO, LS 2023 (pp. FM1E.2). Online: Optical Society of America. DOI
2021	Li, J., Capon, P. K., Horsfall, A. J., Yagoub, S., Schartner, E. P., Khalid, A., . . . Abell, A. D. (2021). Single-fiber-based probe for combined imaging and pH sensing. In Proceedings of the 2021 IEEE Photonics Conference (IPC 2021) (pp. 1-2). online: IEEE. DOI
2019	Dunning, K. R., Campugan, C., Tan, C., Mahbub, S., Goldys, E., Thompson, J., . . . Mustafa, S. (2019). Hyperspectral imaging of the early embryo: can it detect chromosome abnormalities and predict IVF success?. In Label-free Biomedical Imaging and Sensing (LBIS) Vol. 10890:108900I (pp. 1-3). online: SPIE. DOI Scopus2 WoS1
2019	Sylvia, G. M., Schartner, E. P., McLennan, H. J., Saini, A., Dunning, K. R., Purdey, M. S., . . . Thompson, J. G. (2019). High precision pH measurements in biological environments using a portable optical fibre pH sensor. In E. M. Goldys, & B. C. Gibson (Eds.), Biophotonics Australasia 2019 Vol. 11202 (pp. 112020F-1-112020F-2). Bellingham, Washington: SPIE. DOI
2011	Russell, D. L., Matson, L. N., Dunning, K. R., Thompson, J. G., Robker, R. L., & Gilchrist, R. B. (2011). Patterning the Response to Oocyte Signals in Ovarian Follicle Morphogenesis.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION.
2011	Akison, L. K., Alvino, E. R., Dunning, K. R., Robker, R. L., & Russell, D. L. (2011). Migratory, Invasive and Adhesive Phenotypes Are Transiently Induced in the Cumulus Oocyte Complex at Ovulation.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION.
2010	Dunning, K., Norman, R., & Robker, R. (2010). The Importance of Fatty Acid Oxidation in a 3-D Ovarian Follicle Culture System: Increased β-oxidation and Improved Oocyte Developmental Competence in Response to L-carnitine. In AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY Vol. 50 (pp. 24). WILEY-BLACKWELL PUBLISHING, INC.
2010	Dunning, K. R., Cashman, K., Russell, D. L., Thompson, J., Norman, R., & Robker, R. L. (2010). Increased Beta-Oxidation, ATP Levels, and Improved Oocyte Developmental Competence in Response to L-Carnitine. In BIOLOGY OF REPRODUCTION (pp. 84). Milwaukee, WI: SOC STUDY REPRODUCTION.
2010	Yang, X., Wu, L. L., Dunning, K. R., Norman, R. J., Liang, X., & Robker, R. L. (2010). OBESITY ON INCREASES LIPID DROPLETS AND LIPOTOXICITY RESPONSES IN THE PERIOVULATORY CUMULUS-OOCYTECOMPLEX.. In FERTILITY AND STERILITY Vol. 94 (pp. S138-S139). Denver, CO: ELSEVIER SCIENCE INC. DOI
2010	Wu, L. L., Dunning, K. R., Yang, X., Russell, D. L., Norman, R. J., & Robker, R. L. (2010). Oocytes Exhibit Lipid Accumulation, Endoplasmic Reticulum Stress, Mitochondrial Dysfunction, and Apoptosis in Response to High Fat Diet. In BIOLOGY OF REPRODUCTION (pp. 91). Milwaukee, WI: SOC STUDY REPRODUCTION. WoS1
2009	Dunning, K. R., Cashman, K., Russell, D. L., Norman, R. N., & Robker, R. L. (2009). The Role of Beta-Oxidation During Oocyte Maturation and Embryo Development.. In BIOLOGY OF REPRODUCTION (pp. 54). Pittsburgh, PA: SOC STUDY REPRODUCTION.
2008	Dunning, K. R. (2008). Normal follicle growth and maturation in a three-dimensional in vitro culture system: follicular environment manipulation and assessment of oocyte outcomes.. In Reproduction, Fertility and Development Vol. 20 (pp. 108). Australia: CSIRO Publishing.
2007	Dunning, K., Lane, M., Brown, H., Yeo, C., Thompson, J., Robker, R., & Russell, D. (2007). Altered cumulus oocyte matrix following in vitro maturation of oocytes.. In BIOLOGY OF REPRODUCTION Vol. 77 (pp. 199). San Antonio, TX: SOC STUDY REPRODUCTION. DOI WoS1
2006	Russell, D. L., Brown, H. M., Dunning, K. R., Pritchard, M. A., & Robker, R. L. (2006). Ovarian folliculogenesis and lymphangiogenesis are dependent on ECM remodelling by the protease ADAMTS-1.. In BIOLOGY OF REPRODUCTION (pp. 109). Univ Nebraska Med Ctr, Omaha, NE: SOC STUDY REPRODUCTION.
2005	Dunning, K., Yeo, C., & Russell, D. (2005). Altered matrix composition of cumulus oocyte complexes following in vitro maturation. In Reproduction Fertility and Development Vol. 17 (pp. 90). C S I R O Publishing. DOI

Conference Items

Year	Citation
2023	Dunning, K., Campugan, C., Lim, M., Chow, D., Tan, T., Li, T., . . . Dholakia, K. (2023). Does imaging affect embryo health? Comparative analysis of discrete wavelengths of light on the developing embryo. Poster session presented at the meeting of Abstracts of the 39th European Society of Human Reproduction and Embryology (ESHRE, 2023) as published in Human Reproduction. Copenhagen, Denmark: Oxford University Press. DOI
2021	Tan, C. Y., Mahbub, S. B., Campugan, C. A., Campbell, J., Habibalahi, A., Chow, D. J. X., . . . Dunning, K. R. (2021). Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo. Poster session presented at the meeting of Abstracts of the 37th Annual Meeting of the European Society of Human Reproduction and Embryology, as published in Human Reproduction. virtual online: Oxford University Press (OUP). DOI
2012	Sutton-McDowall, M., Feil, D., Robker, R., Thompson, J., & Dunning, K. (2012). UTILISATION OF ENDOGENOUS FATTY ACID STORES FOR ENERGY PRODUCTION IN BOVINE PRE-IMPLANTATION EMBRYOS. Poster session presented at the meeting of REPRODUCTION FERTILITY AND DEVELOPMENT. CSIRO PUBLISHING. DOI

Preprint

Year	Citation
2024	Peterkovic, Z., Upadhya, A., Perrella, C., Bajraktarevic, A., Gonzalez, R. B., Lim, M., . . . Dholakia, K. (2024). Optimising image capture for low-light widefield quantitative fluorescence microscopy.

2024-2027 NHMRC Ideas Grant. Suspended by sound: A novel approach to grow developmentally competent oocytes in vitro, $1,387,127.

2021-24 NHMRC Ideas Grant. A new light on diagnosing embryo health, $1,266,777

2022-24 Australasian Pork Research Institute Limited, Precision monitoring of reproductive state via development of pen side mucus testing and continuous remote monitoring, CI Dunning, $414,438

2014-20 ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), $38M (total), $5.4M pro rata – duration for which I was a Chief Investigator

2019 Awarded competitive joint Adelaide/Nottingham (UK) PhD scholarship for the group, Utilising light and sound for ART (assisted reproductive technologies), $120,000

2020-23 The Hospital Research Foundation Mid-Career Fellowship, Determining embryo health with a light touch: label-free imaging to detect chromosome mosaicism, $406,750

2020 Barbara Kidman Fellowship, The University of Adelaide $30,000

2020 Robinson Research Institute Innovation Seed Grant, $25,000

2018 Faculty of Health and Medical Sciences, Emerging Leadership Development Program, $40,000

2018 Robinson Research Institute, Invest for Success Grant, $28,250

2018 Faculty of Health and Medical Sciences, Emerging Leadership Development Program, $40,000

2018 Robinson Research Institute, Invest for Success Grant, $28,250

2018 Ian Potter Foundation Research Grant: Vevo 3100; $360,000, AI Dunning

2017 Robinson Research Institute Career Development Fellowship, $60,000

2012-17 ARC Discovery Early Career Award (DECRA), Biomimetic systems for species preservation and fertility restoration, $375,000

2017 Robinson Research Institute Grant, Story telling and science of pregnancy loss. CIB Dunning, $18,000

2017 Society for Reproductive Biology, ECR Collaborative Research Award, $1500

2015 Robinson Research Institute Innovation Seed Grant, Preventing and Alleviating Infertility: Enabling the best start in life, CIC Dunning, $25,000

2012 Channel 7 Children’s Foundation Research Grant, The impact of lipotoxicity in the ovaries and oocytes of obese women on embryo health, CIB Dunning, $48,000

2011 Women’s and Children’s Hospital Foundation Research Project Grant, Modulating Lipid Metabolism to Improve the Growth of Follicles and Oocytes in vitro, $50,000

2011 Channel 7 Children’s Foundation Research Grant, Preservation of Female Fertility, $35,000

2024 Lecturer: Life-course (third year, Medicine Degree, Bachelor of Medical Studies)

2023 Lecturer: Principles of Human Health and Disease (first year, Bachelor of Health and Medical Sciences)

2023 Lecturer: Investigative Cell Biology (third year, Bachelor of Health and Medical Sciences)

2014-2017 Lecturer, Research Projects in Reproductive Health, University of Adelaide

2015 Lecturer, Human Reproductive Health III, University of Adelaide

2010-2015 Lecturer, Honours Program, School of Paediatrics & Reproductive Health

2006-2007 Tutor, Bachelor of Surgery (MBBS) students

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2024	Principal Supervisor	Investigate the impact of discrete wavelengths of light on preimplantation embryo development.	Doctor of Philosophy	Doctorate	Full Time	Miss Shan Li
2023	Principal Supervisor	Does cryopreservation induce aneuploidy in embryos?	Doctor of Philosophy	Doctorate	Full Time	Ms Tong Li
2022	Co-Supervisor	Advanced Methods of Beam Shaping and Their Implementation in Multiphoton Microscopy	Doctor of Philosophy	Doctorate	Full Time	Mr Ramses Eduardo Bautista Gonzalez
2020	Co-Supervisor	Improving in vitro maturation of oocytes by bringing research together: can we get synergy?	Doctor of Philosophy	Doctorate	Part Time	Ms Annie Louise Whitty
2020	Principal Supervisor	Utilising light and sound in Assisted Reproductive Technologies	Doctor of Philosophy under a Jointly-awarded Degree Agreement with	Doctorate	Full Time	Mr Carl Adrian Campugan
2017	Co-Supervisor	Non-reproductive uses of Zonae Pellucida	Master of Philosophy (Medical Science)	Master	Full Time	Avishkar Saini

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2019 - 2024	Principal Supervisor	Label-free Optical Approaches for the Non-invasive Assessment of Embryo Quality	Doctor of Philosophy	Doctorate	Full Time	Mr Darren Jin Xiang Chow
2018 - 2023	Principal Supervisor	Towards Automation of In Vitro Fertilisation (IVF)	Doctor of Philosophy	Doctorate	Full Time	Mr Suliman Hassan Suliman Yagoub
2017 - 2020	Co-Supervisor	The Role of Haemoglobin in Healthy Oocyte Development	Doctor of Philosophy	Doctorate	Full Time	Ms Megan Lim
2017 - 2022	Principal Supervisor	Optical imaging detects metabolic signatures associated with oocyte and embryo quality	Doctor of Philosophy	Doctorate	Full Time	Miss Cheow Yuen Tan

Committee Memberships

Date	Role	Committee	Institution	Country
2024 - ongoing	Co-Chair	Program Organising Committee	Society for Reproductive Biology	Australia
2022 - 2025	Chair	MS McLeod Research Fund	Women's & Children's Hospital Research Foundation	Australia
2019 - 2022	Member	Society for Reproductive Biology Committee	Society for Reproductive Biology	Australia
2018 - ongoing	Co-Chair	Local Organising Committee	Society for Reproductive Biology	Australia

Memberships

Date	Role	Membership	Country
2023 - ongoing	Member	SPIE. The international society for optics and photonics	Australia
2007 - ongoing	Member	Society for the Study of Reproduction	United States
2005 - ongoing	Member	Society for Reproductive Biology	Australia

Editorial Boards

Date	Role	Editorial Board Name	Institution	Country
2024 - ongoing	Editor	Journal of Assisted Reproduction and Genetics	Springer Nature	United States
2018 - ongoing	Board Member	Scientific Reports	Nature Portfolio	United Kingdom

Position: Ext-Funded Research Fellow (D)
Phone: 83131013
Email: kylie.dunning@adelaide.edu.au
Campus: North Terrace
Building: Helen Mayo South, floor 2
Org Unit: Medical Sciences