Lee-anne Chapple
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Associate Professor Lee-anne Chapple.
Lee-anne Chapple is a clinical dietitian with experience in clinical dietetics, tertiary-education, and research. She was awarded her PhD in July 2017, which explored nutritional intake and muscle wasting in patients admitted to intensive care with a traumatic brain injury.
Lee-anne is currently a post-doctoral fellow with the RAH ICU Research team where she is interested in developing strategies to better feed critically ill patients to prevent muscle wasting and improve their long-term functional outcomes and quality of life.
Skills and expertise:
Nutrition, Human Nutrition, Clinical Nutrition, Muscle Metabolism, Body Composition, Dietetics, Traumatic Brain Injury, Anthropometry.
I lead the Nutrition Program in Intensive Care at the Royal Adelaide Hospital. My research focus is the role of nutrition to attenuate muscle loss and optimise functional recovery for critically ill patients, incorporating study designs from small observational data, to complex physiological studies and randomised clinical trials.
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Appointments
Date Position Institution name 2023 - ongoing Associate Professor University of Adelaide 2019 - 2023 NHMRC Early Career Fellow University of Adelaide 2017 - 2023 Affiliate Lecturer University of Adelaide 2017 - ongoing Senior Critical Care Dietitian Royal Adelaide Hospital -
Awards and Achievements
Date Type Title Institution Name Country Amount 2022 Honour Honours Supervisor of the Year Flinders University Australia - 2020 Award Best Abstract, ESPEN Congress European Society of Clinical Nutrition and Metabolism Australia - 2017 Award Research Section New Practitioner Award American Society of Parenteral and Enteral Nutrition (ASPEN) Australia - 2017 Award Ross Wishart Memorial Award Australian Society of Medical Research Australia - 2016 Award International Abstract Award ASPEN Australia - 2016 Award International Abstract of Distinction ASPEN United States - 2016 Award Conference Travel Grant Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Australia - 2016 Award Best Allied Health Paper. Australian and New Zealand Intensive Care Society Australia - -
Education
Date Institution name Country Title 2017 University of Adelaide Australia PhD 2008 Flinders University Australia Master of Nutrition and Dietetics 2005 Flinders University Australia Bachelor of Medical Science -
Research Interests
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Journals
Year Citation 2024 Chapple, L. A. S., Ridley, E. J., Ainscough, K., Ballantyne, L., Burrell, A., Campbell, L., . . . Udy, A. (2024). Nutrition delivery across hospitalisation in critically ill patients with COVID-19: An observational study of the Australian experience. Australian Critical Care, 37(3), 422-428.
Scopus22024 Louis, R., Weinel, L. M., Burrell, A., Gardner, B., McEwen, S., Chapman, M. J., . . . Chapple, L. A. S. (2024). Observed differences in nutrition management at two time points spanning a decade in critically ill trauma patients with and without head injury. Australian Critical Care, 37(3), 414-421.
Scopus12024 Yadav, N., Chapple, L. A. S., O'Connor, S., Worthington, M., Reddi, B., & Sundararajan, K. (2024). Characteristics, incidence, and outcomes of gastrointestinal complications post cardiac surgery in a quaternary referral centre: A retrospective study. Australian Critical Care, 37(4), 571-576.
Scopus22024 Viner Smith, E., Kouw, I. W. K., Summers, M. J., Louis, R., Trahair, L., O'Connor, S. N., . . . Chapple, L. -A. S. (2024). Comparison of energy intake in critical illness survivors, general medical patients and healthy volunteers: A descriptive cohort study. JPEN J Parenter Enteral Nutr, 48(3), 275-283.
Scopus22024 Viner Smith, E., Lambell, K., Tatucu-Babet, O. A., Ridley, E., & Chapple, L. A. (2024). Nutrition considerations for patients with persistent critical illness: A narrative review. Journal of Parenteral and Enteral Nutrition, 48(6), 658-666.
Scopus12024 Viner Smith, E., Kouw, I. W. K., Summers, M. J., Louis, R., Chapman, M. J., & Chapple, L. A. S. (2024). Evaluating physiological barriers to oral intake in hospitalized patients: A secondary analysis. Journal of Parenteral and Enteral Nutrition, 48(7), 833-840.
2024 Samm, D. A., Macoustra, A., Crane, R., McWilliams, L., Proudman, S., & Chapple, L. A. S. (2024). Views of nutrition needs in patients with systemic sclerosis. Journal of Scleroderma and Related Disorders, 9(3), 216-222.
2024 Viner Smith, E., Summers, M. J., Asser, I., Louis, R., Lange, K., Ridley, E. J., & Chapple, L. A. S. (2024). Nutrition intake, muscle thickness, and recovery outcomes for critically ill patients requiring non-invasive forms of respiratory support: A prospective observational study. Australian Critical Care, S1036-7314(24)00207-8.
2024 Chapple, L. A. S., & Kelly, P. (2024). Special issue: Challenges and Opportunities for ICU Recovery. Australian Critical Care, 37(6), 835-836.
2024 Wittholz, K., Fetterplace, K., Chapple, L. A., Ridley, E. J., Finnis, M., Presneill, J., . . . Deane, A. M. (2024). Six-month outcomes after traumatic brain injury in the Augmented versus Routine Approach to Giving Energy multicentre, double-blind, randomised controlled Trial (TARGET). Australian Critical Care, 101116.
2024 Page, K., Viner Smith, E., Plummer, M. P., Ridley, E. J., Burfield, K., & Chapple, L. -A. S. (2024). Nutrition practices in critically ill adults receiving noninvasive ventilation: A quantitative survey of Australian and New Zealand intensive care clinicians. Australian Critical Care, 37(1), 43-50.
Scopus22023 Summers, M. J., Chapple, L. A. S., Bellomo, R., Chapman, M. J., Ferrie, S., Finnis, M. E., . . . Deane, A. M. (2023). Study protocol for TARGET protein: The effect of augmented administration of enteral protein to critically ill adults on clinical outcomes: A cluster randomised, cross-sectional, double cross-over, clinical trial. Critical Care and Resuscitation, 25(3), 147-154.
Scopus7 Europe PMC12023 Page, K., Viner Smith, E., & Chapple, L. S. (2023). Nutrition practices in hospitalized adults receiving noninvasive forms of respiratory support: A scoping review. Nutrition in Clinical Practice, 39(2), 344-355.
Scopus12023 Davies, T. W., Kelly, E., van Gassel, R. J. J., van de Poll, M. C. G., Gunst, J., Casaer, M. P., . . . Puthucheary, Z. A. (2023). A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE). Critical Care, 27(1), 16 pages.
Scopus12023 Samm, D. -A. A., Macoustra, A. R., Crane, R. K., McWilliams, L. M., Proudman, S. M., & Chapple, L. -A. S. (2023). A survey of Australian rheumatologists’ perspectives of nutrition needs in systemic sclerosis. Journal of Scleroderma and Related Disorders, 8(3), 203-209.
2023 Viner Smith, E., D'Cruz, R. F., & Chapple, L. A. (2023). Nutrition therapy during noninvasive ventilation: Oral or enteral?. Current Opinion in Critical Care, 29(4), 346-353.
Scopus1 WoS1 Europe PMC12023 Ridley, E. J., Chapple, L. A. S., Ainscough, K., Burrell, A., Campbell, L., Dux, C., . . . Udy, A. (2023). Nutrition care processes across hospitalisation in critically ill patients with COVID-19 in Australia: A multicentre prospective observational study. Australian Critical Care, 36(6), 955-960.
2023 Ridley, E. J., & Chapple, L. -A. S. (2023). Nutrition in critical illness-research is worth the EFFORT. LANCET, 401(10376), 527-528.
Scopus12022 Whitehead, J., Summers, M. J., Louis, R., Weinel, L. M., Lange, K., Dunn, B., . . . Chapple, L. -A. S. (2022). Assessment of physiological barriers to nutrition following critical illness. Clinical Nutrition, 41(1), 11-20.
Scopus5 WoS32022 Ridley, E. J., Bailey, M., Chapman, M., Chapple, L. A. S., Deane, A. M., Hodgson, C., . . . Udy, A. A. (2022). Protocol summary and statistical analysis plan for i ntensive N utrition T herapy compar e d to usual care i N cri T ically ill adults (INTENT): A phase II randomised controlled trial. BMJ Open, 12(3), 13 pages.
Scopus8 WoS7 Europe PMC32022 Viner Smith, E., Ridley, E. J., Rayner, C. K., & Chapple, L. -A. S. (2022). Nutrition management for critically ill adult patients requiring non-Invasive ventilation: A scoping review. Nutrients, 14(7), 1446-1-1446-14.
Scopus9 WoS3 Europe PMC22022 Murthy, T. A., Chapple, L. -A. S., Lange, K., Marathe, C. S., Horowitz, M., Peake, S. L., & Chapman, M. J. (2022). Gastrointestinal dysfunction during enteral nutrition delivery in ICU patients: Risk factors, natural history and clinical implications. A post-hoc analysis of the TARGET trial. The American Journal of Clinical Nutrition, 116(2), 589-598.
Scopus22 WoS11 Europe PMC82022 Chapple, L. -A. S., Kouw, I. W. K., Summers, M. J., Weinel, L. M., Gluck, S., Raith, E., . . . Chapman, M. J. (2022). Muscle Protein Synthesis Following Protein Administration in Critical Illness. American Journal of Respiratory and Critical Care Medicine, 206(6), 740-749.
Scopus44 WoS19 Europe PMC242022 Ridley, E. J., & Chapple, L. A. S. (2022). Time to combine: Integrating physical therapy and nutrition. Intensive and Critical Care Nursing, 71, 103263.
Scopus1 WoS12022 Noyahr, J. K., Tatucu-Babet, O. A., Chapple, L. A. S., Barlow, C. J., Chapman, M. J., Deane, A. M., . . . Ridley, E. J. (2022). Systematic Review Methodological Rigor and Transparency in Clinical Practice Guidelines for Nutrition Care in Critically Ill Adults: A Systematic Review Using the AGREE II and AGREE-REX Tools. Nutrients, 14(13), 12 pages.
Scopus7 WoS4 Europe PMC52022 Viner Smith, E., Ridley, E. J., Rayner, C. K., & Chapple, L. A. S. (2022). Nutrition management of critically ill adult patients requiring non-invasive ventilation: A scoping review protocol. JBI Evidence Synthesis, 20(7), 1814-1820.
Scopus1 WoS1 Europe PMC12022 Chapple, L. -A. S., van Gassel, R. J. J., & Rooyackers, O. (2022). Protein metabolism in critical illness. CURRENT OPINION IN CRITICAL CARE, 28(4), 367-373.
Scopus8 WoS6 Europe PMC42022 Davies, T. W., van Gassel, R. J. J., van de Poll, M., Gunst, J., Casaer, M. P., Christopher, K. B., . . . Puthucheary, Z. A. (2022). Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE). Critical Care, 26(1), 12 pages.
Scopus33 WoS18 Europe PMC182022 Murthy, T. A., Plummer, M. P., Tan, E., Chapman, M. J., & Chapple, L. -A. S. (2022). Higher versus lower enteral calorie delivery and gastrointestinal dysfunction in critical illness: A systematic review and meta-analysis. Clinical Nutrition, 41(10), 2185-2194.
Scopus5 WoS4 Europe PMC12022 Chapple, L. -A. S., Summers, M. J., Weinel, L. M., Lange, K., Yang, W. H., Deane, A. M., . . . TARGET Investigators for the Australia and New Zealand Intensive Care Society Clinical Trials Group. (2022). Muscle size, strength, and physical function in response to augmented calorie delivery: A TARGET sub-study.. Journal of critical care, 72, 154140.
Scopus5 WoS5 Europe PMC32022 Chapple, L. -A. S., Parry, S. M., & Schaller, S. J. (2022). Attenuating Muscle Mass Loss in Critical Illness: the Role of Nutrition and Exercise. CURRENT OSTEOPOROSIS REPORTS, 20(5), 290-308.
Scopus13 WoS5 Europe PMC52022 Wong, H. Z., Brusseleers, M., Hall, K. A., Maiden, M. J., Chapple, L. -A. S., Chapman, M. J., . . . Gluck, S. (2022). Mixed-mode versus paper surveys for patient-reported outcomes after critical illness: A randomised controlled trial. Australian Critical Care, 35(3), 286-293.
Scopus2 Europe PMC12021 Lyons, G. C. E., Summers, M. J., Schultz, T. J., Lambell, K., Ridley, E. J., Fetterplace, K., . . . Chapple, L. S. (2021). Protein prescription and delivery practices in critically ill adults: A survey of Australian and New Zealand intensive care dietitians. Australian Critical Care, 35(5), 543-549.
Scopus2 WoS12021 Lyons, G. C. E., Summers, M. J., Marshall, A. P., & Chapple, L. (2021). Systematic review of clinicians' knowledge, attitudes, and beliefs about nutrition in intensive care. Nutr Clin Pract, 37(4), 18 pages.
Scopus5 WoS3 Europe PMC12021 Chapple, L. -A. S., Summers, M. J., Bellomo, R., Chapman, M. J., Davies, A. R., Ferrie, S., . . . TARGET Investigator Collaborative and the ANZICS Clinical Trials Group. (2021). Use of a high-protein enteral nutrition formula to increase protein delivery to critically ill patients: a randomized, blinded, parallel-group, feasibility trial. Journal of Parenteral and Enteral Nutrition, 45(4), 699-709.
Scopus26 WoS16 Europe PMC122021 Chapple, L. -A. S., Plummer, M. P., & Chapman, M. J. (2021). Gut dysfunction in the ICU: diagnosis and management.. Current opinion in critical care, 27(2), 141-146.
Scopus10 WoS9 Europe PMC62021 Chapple, L. -A. S., Summers, M. J., Weinel, L. M., Abdelhamid, Y. A., Kar, P., Hatzinikolas, S., . . . Chapman, M. J. (2021). Effects of Standard Versus Energy-Dense Formulae on Gastric Retention, Caloric Delivery, and Glycaemia in Critically Ill Patients.. JPEN J Parenter Enteral Nutr, 45(4), 710-719.
Scopus8 WoS9 Europe PMC52021 Weinel, L., Summers, M., Poole, A., & Chapple, L. (2021). Are point-of-care urine albumin–creatinine ratio measurements accurate in the critically ill?. Australian Critical Care, 34(6), 569-572.
2021 Chapple, L. A. S., Dirks, M. L., & Kouw, I. W. K. (2021). Stable isotope approaches to study muscle mass outcomes in clinical populations. Clinical Nutrition Open Science, 36, 98-108.
Scopus22021 Egan, T., Chapple, L. A., Morgan, H., Rassias, G., & Yandell, R. (2021). Nutritional risk screening in noninvasively mechanically ventilated critically ill adult patients: A feasibility trial. Australian Critical Care, 35(2), 153-158.
Scopus5 WoS2 Europe PMC22021 Chapple, L. A. S., Tatucu-Babet, O. A., Lambell, K. J., Fetterplace, K., & Ridley, E. J. (2021). Nutrition guidelines for critically ill adults admitted with COVID-19: Is there consensus?. Clinical Nutrition ESPEN, 44, 69-77.
Scopus34 WoS22 Europe PMC222021 Arunachala Murthy, T., Bellomo, R., Chapman, M., Deane, A., Ferrie, S., Finnis, M., . . . Chapple, L. -A. (2021). Protein delivery in mechanically ventilated adults in Australia and New Zealand: current practice. Critical Care and Resuscitation, 23(4), 386-393.
Scopus8 WoS2 Europe PMC12021 Sierp, E. L., Kurmis, R., Lange, K., Yandell, R., Chapman, M., Greenwood, J., . . . Kurmis, R. (2021). Nutrition and Gastrointestinal Dysmotility in Critically Ill Burn Patients: A Retrospective Observational Study.. JPEN J Parenter Enteral Nutr, 45(5), 1052-1060.
Scopus12 WoS7 Europe PMC72021 Murthy, T. A., Grivell, J., Hatzinikolas, S., Chapple, L. -A. S., Chapman, M. J., Stevens, J. E., . . . Marathe, C. S. (2021). Acceleration of gastric emptying by insulin-induced hypoglycemia is dependent on the degree of hypoglycemia. The Journal of Clinical Endocrinology and Metabolism, 106(2), 364-371.
Scopus5 WoS4 Europe PMC32020 Chapple, L. -A. S., Ridley, E. J., & Chapman, M. J. (2020). Trial design in critical care nutrition: the past, present and future. Nutrients, 12(12), 3694-1-3694-11.
Scopus11 WoS9 Europe PMC62020 Seddon, N., Chapple, L. A. S., Tatucu-Babet, O. A., & Ridley, E. J. (2020). Reporting of Randomized Controlled Trials Investigating an Enteral or Parenteral Nutrition Intervention in Critical Illness According to the CONSORT Statement: A Systematic Review and Recommendation of Minimum Standard Reporting Criteria. Journal of Parenteral and Enteral Nutrition, 45(3), 14 pages.
Scopus4 WoS4 Europe PMC12020 Chapple, L. -A. S., Weinel, L., Ridley, E. J., Jones, D., Chapman, M. J., & Peake, S. L. (2020). Clinical Sequelae From Overfeeding in Enterally Fed Critically Ill Adults: Where Is the Evidence?. JPEN. Journal of parenteral and enteral nutrition, 44(6), 980-991.
Scopus13 WoS11 Europe PMC62020 Albrich, L., Chapple, L. A. S., Nock, A., Ridley, E. J., & Hickson, M. (2020). Nutrition-related symptoms in adult survivors of critical illness who are eating orally: a scoping review protocol. JBI evidence synthesis, 18(6), 1326-1333.
Scopus1 WoS12020 Chapple, L., Fetterplace, K., Asrani, V., Burrell, A., Cheng, A. C., Collins, P., . . . Ridley, E. J. (2020). Nutrition management for critically and acutely unwell hospitalised patients with coronavirus disease 2019 (COVID-19) in Australia and New Zealand.. Nutr Diet, 77(4), 426-436.
Scopus26 WoS19 Europe PMC202020 Marshall, A. P., Austin, D. E., Chamberlain, D., Chapple, L. A. S., Cree, M., Fetterplace, K., . . . Williams, L. (2020). A critical care pandemic staffing framework in Australia. Australian Critical Care, 34(2), 123-131.
Scopus26 WoS25 Europe PMC172020 Chapple, L. A., Gan, M., Louis, R., Yaxley, A., Murphy, A., & Yandell, R. (2020). Nutrition-related outcomes and dietary intake in non–mechanically ventilated critically ill adult patients: A pilot observational descriptive study. Australian Critical Care, 33(3), 300-308.
Scopus21 Europe PMC82020 Chapple, L. A. S., Fetterplace, K., Asrani, V., Burrell, A., Cheng, A. C., Collins, P., . . . Ridley, E. J. (2020). Nutrition management for critically and acutely unwell hospitalised patients with coronavirus disease 2019 (COVID-19) in Australia and New Zealand. Australian Critical Care, 33(5), 399-406.
Scopus38 WoS29 Europe PMC252020 Yk Yeo, N., Aj Reddi, B., Schultz, C. G., O'Connor, S. N., Chapman, M. J., & S Chapple, L. -A. (2020). Early anthropometry, strength, and function in survivors of critical illness.. Australian critical care : official journal of the Confederation of Australian Critical Care Nurses, 34(1), 33-37.
Scopus3 WoS12020 Ridley, E. J., Chapple, L. A. S., & Chapman, M. J. (2020). Nutrition intake in the post-ICU hospitalization period. Current Opinion in Clinical Nutrition and Metabolic Care, 23(2), 111-115.
Scopus37 WoS25 Europe PMC112020 Lambell, K. J., Tatucu-Babet, O. A., Chapple, L. A., Gantner, D., & Ridley, E. J. (2020). Nutrition therapy in critical illness: a review of the literature for clinicians. Critical care (London, England), 24(1), 11 pages.
Scopus77 WoS53 Europe PMC232020 Chapple, L., Summers, M. J., Weinel, L. M., & Deane, A. M. (2020). Outcome Measures in Critical Care Nutrition Interventional Trials: A Systematic Review.. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 35(3), 506-513.
Scopus13 WoS12 Europe PMC52020 Fetterplace, K., Gill, B. M. T., Chapple, L., Presneill, J. J., MacIsaac, C., & Deane, A. M. (2020). Systematic Review With Meta-Analysis of Patient-Centered Outcomes, Comparing International Guideline-Recommended Enteral Protein Delivery With Usual Care.. JPEN. Journal of parenteral and enteral nutrition, 44(4), 610-620.
Scopus23 WoS17 Europe PMC82019 Weinel, L. M., Summers, M. J., & Chapple, L. -A. (2019). Ultrasonography to measure quadriceps muscle in critically ill patients: A literature review of reported methodologies.. Anaesthesia and intensive care, 47(5), 423-434.
Scopus43 WoS28 Europe PMC152019 Chapple, L. S., Weinel, L. M., Ali Abdelhamid, Y., Summers, M. J., Nguyen, T. A. N., Kar, P., . . . Deane, A. M. (2019). Observed appetite and nutrient intake three months after ICU discharge. Clinical Nutrition, 38(3), 1215-1220.
Scopus23 WoS17 Europe PMC92019 Albrich, L., Chapple, L. -A. S., Nock, A., Ridley, E. J., & Hickson, M. (2019). Nutrition-related symptoms in adult survivors of critical illness when eating orally: a scoping review protocol.. JBI database of systematic reviews and implementation reports.
2018 Parry, S. M., Chapple, L. -A. S., & Mourtzakis, M. (2018). Exploring the potential effectiveness of combining optimal nutrition with electrical stimulation to maintain muscle health in critical illness: a narrative review. Nutrition in Clinical Practice, 33(6), 772-789.
Scopus14 WoS12 Europe PMC82018 Chapple, L. -A., Chapman, M., Shalit, N., Udy, A., Deane, A., & Williams, L. (2018). Barriers to nutrition intervention for patients with a traumatic brain injury: views and attitudes of medical and nursing practitioners in the acute care setting. Journal of Parenteral and Enteral Nutrition, 42(2), 318-326.
Scopus22 WoS16 Europe PMC92018 Chapple, L. A., & Deane, A. (2018). From dysmotility to virulent pathogens: Implications of opioid use in the ICU. Current Opinion in Critical Care, 24(2), 118-123.
Scopus9 WoS7 Europe PMC32017 Chapple, L., Deane, A., Lange, K., Kranz, A., Williams, L., & Chapman, M. (2017). Weekend days are not required to accurately measure oral intake in hospitalised patients. Journal of Human Nutrition and Dietetics, 30(3), 378-384.
Scopus2 WoS1 Europe PMC12017 Nguyen, T. A., Abdelhamid, Y. A., Phillips, L. K., Chapple, L. S., Horowitz, M., Jones, K. L., & Deane, A. M. (2017). Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients.. World journal of critical care medicine, 6(1), 28-36.
Europe PMC22017 Miller, A., Deane, A., Plummer, M., Cousins, C., Chapple, L., Horowitz, M., & Chapman, M. (2017). Exogenous glucagon-like peptide-1 attenuates glucose absorption and reduces blood glucose concentration after small intestinal glucose delivery in critical illness. Critical Care and Resuscitation, 19(1), 37-42.
Scopus11 WoS9 Europe PMC62017 Chapple, L. A. S., Deane, A. M., Williams, L. T., Strickland, R., Schultz, C., Lange, K., . . . Chapman, M. J. (2017). Longitudinal changes in anthropometrics and impact on self-reported physical function after traumatic brain injury. Critical Care and Resuscitation, 19(1), 29-36.
Scopus42 WoS25 Europe PMC102017 Gluck, S., Chapple, L. S., Chapman, M. J., Iwashyna, T. J., & Deane, A. M. (2017). A scoping review of use of wearable devices to evaluate outcomes in survivors of critical illness. Critical Care and Resuscitation, 19(3), 197-204.
Scopus9 WoS7 Europe PMC42017 Davies, M. L., Chapple, L. A. S., Chapman, M. J., Moran, J. L., & Peake, S. L. (2017). Protein delivery and clinical outcomes in the critically ill: A systematic review and meta-analysis. Critical Care and Resuscitation, 19(2), 117-127.
Scopus42 WoS35 Europe PMC172016 Chapple, L., Chapman, M., Lange, K., Deane, A., & Heyland, D. (2016). Nutrition support practices in critically ill head-injured patients: a global perspective. Critical Care, 20(1), 6-1-6-11.
Scopus33 WoS21 Europe PMC102016 Summers, M., S Chapple, L., McClave, S., & Deane, A. (2016). Event-rate and delta inflation when evaluating mortality as a primary outcome from randomized controlled trials of nutritional interventions during critical illness: a systematic review. American Journal of Clinical Nutrition, 103(4), 1083-1090.
Scopus18 WoS15 Europe PMC92016 Chapple, L. A. S., Deane, A. M., Heyland, D. K., Lange, K., Kranz, A. J., Williams, L. T., & Chapman, M. J. (2016). Energy and protein deficits throughout hospitalization in patients admitted with a traumatic brain injury. Clinical Nutrition, 35(6), 1315-1322.
Scopus96 WoS64 Europe PMC372016 Reid, D. B., Chapple, L. S., O'Connor, S. N., Bellomo, R., Buhr, H., Chapman, M. J., . . . Deane, A. M. (2016). The effect of augmenting early nutritional energy delivery on quality of life and employment status one year after ICU admission. Anaesthesia and Intensive Care, 44(3), 406-412.
Scopus13 WoS11 Europe PMC62016 Liew, V. Y., Chapman, M. J., Nguyen, N. Q., Cousins, C. E., Plummer, M. P., Chapple, L. A. S., . . . Deane, A. M. (2016). A prospective observational study of the effect of critical illness on ultrastructural and microscopic morphology of duodenal mucosa. Critical Care and Resuscitation, 18(2), 102-108.
Scopus6 WoS6 Europe PMC52015 Costello, L., Chapman, M., Deane, A., Lange, K., & Heyland, D. (2015). Nutrition support practices in critically ill head injured patients: A global perspective. Intensive Care Medicine Experimental, 3(Suppl 1), A984.
Scopus32015 Dodd, J. M., Ahmed, S., Karnon, J., Umberger, W., Deussen, A. R., Tran, T., . . . Robinson, J. S. (2015). The cost-effectiveness of providing antenatal lifestyle advice for women who are overweight or obese: the LIMIT randomised trial. BMC Obesity, 2(1), 14-1-14-9.
Scopus16 Europe PMC132014 Costello, L. -A., Lithander, F., Gruen, R., & Williams, L. (2014). Nutrition therapy in the optimisation of health outcomes in adult patients with moderate to severe traumatic brain injury: findings from a scoping review. Injury, 45(12), 1834-1841.
Scopus26 WoS22 Europe PMC132013 Sui, Z., Moran, L., Costello, L., & Dodd, J. (2013). Agreement between a food frequency questionnaire and the Willett questionnaire in overweight or obese pregnant women. Journal of Nutritional Therapeutics, 2(2), 89-99.
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Book Chapters
Year Citation 2022 Chapple, L. -A., Ridley, E., Burrell, A., & Fetterplace, K. (2022). Coronavirus Disease 2019 (COVID-19): A Clinical Guide. In M. Dube, & A. Gholamrezanezhad (Eds.), Coronavirus Disease 2019 (Covid-19) A Clinical Guide. Wiley-Blackwell. 2019 Chapple, L. S., & Chapman, M. (2019). Nutrition Support in Critically Ill Surgical Patients. In P. Aseni, L. De Carlis, A. M. Grande, & A. Mazzola (Eds.), Operative Techniques and Recent Advances in Acute Care and Emergency Surgery (pp. 695-705). Cham, Switzerland: Springer.
DOI2019 Bear, D., Chapple, L. S., & Puthucheary, Z. (2019). Rehabilitation: Nutritional strategies. In J. C. Preiser, M. Herridge, & E. Azoulay (Eds.), Post-Intensive Care Syndrome (pp. 295-309). Springer Nature.
DOI Scopus1 -
Conference Papers
Year Citation 2022 Yadav, N., Chapple, L. -A., Reddi, B., Worthington, M., O'Connor, S., & Sundararajan, K. (2022). GASTROINTESTINAL COMPLICATIONS POST CARDIAC SURGERY IN A QUARTENARY REFERRAL CENTRE. In AUSTRALIAN CRITICAL CARE Vol. 35 (pp. S15). ELSEVIER SCIENCE INC. -
Conference Items
Year Citation 2023 Kouw, I. W. K., Chapple, L. -A. S., Louis, R., Summers, M., Jones, K., Horowitz, M., & Chapman, M. (2023). Comparative effects of intermittent and continuous enteral feeding on glycaemic control in critically ill patients. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2020 Murthy, T. A., Grivell, J., Hatzinikolas, S., Raynor, C., Chapman, M. J., Chapple, L. -A., . . . Marathe, C. S. (2020). The magnitude of acceleration of gastric emptying in acute hypoglycaemia in health is dependent on the level of hypoglycaemia. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
Viner Smith E, Chapple L, Ridley E, Plummer M, Peake S. Wittholz K, Haines K. 2023-2024. Title: Enhancing dietAry inTake during NonInvasive Ventilation: a feasibility randomised controlled trial (EAT-NIV). AuSPEN Australasian Society of Parenteral and Enteral Nutrition (AuSPEN). Value: $14,369.55.
Chapple L, Plummer M, Burke A, Haines K, Marshall A, Dafoe S, Summers M, McCade B. 2024-2025. Title: Enhancing recovery for intensive care survivors through an allied health-led follow-up clinic. CALHN CEO CRIPS grant. Value: $200,000.
Davis C, Chapple L, Viner Smith E, Chittleborough E, Reddi B, Peake S. 2024. Title: Nutrition practices in the long-stay critically ill patient. Royal Adelaide Hospital Allied Health, Pharmacy and Nursing Clinical Research Grant. Value: $35,000.
Ridley E, Peake S, Marshall A, Udy A, Hodgson C, Nichol A, Ayton D, Chapple L, Freeman-Sanderson A, Tatucu O, Bailey M, Butt W, Fetterplace K, King V, Winderlich J. 2023-2026. Title: A national platform for improving quality of nutrition care for critically ill adults and children, APP2023953MRFF Clinician Researcher Scheme, Value: $1,499,122.40.
Summers M, Chapple L, Plummer M, Deane A, Lambell K, Fetterplace K, Finnis M. 2022. Skeletal muscle and recovery following augmented protein during critical illness (SMART-PRO). Australasian Society of Parenteral and Enteral Nutrition (AuSPEN). Value: $13,986.75.
Jay A, Chapple L, Sammour T, Overall B. Energy expenditure following pelvic exenteration (REPLETE). Royal Adelaide Hospital Allied Health, Pharmacy and Nursing Clinical Research Grant. Value: $35,000.
Chapple LS. 2022. Nutrition intake and physical recovery for critically ill patients requiring non-invasive ventilation. Emerging Leaders Development Award, Faculty of Health and Medical Sciences. Value: $35,091.
Jones K, Horowitz M, Rayner C, Marathe C, Wu T, Chapple L, Umapathysivam M. 2022. Effect of subcutaneous semaglutide on gastric emptying measured using the 'gold standard' technique, scintigraphy, in type 2 diabetes, Diabetes Australia. Value: $50,000.
Samm D, Chapple L, Crane R, Proudman S, McWilliams L. 2022. Title: ViEws of Nutrition in patients with Scleroderma and their treating Physicians: The VENUS Study. Acraman Bequest - RAH Allied Health Research Grant. Value: $5000
Chapple LS, Deane A, Viner-Smith E, Young P, O’Connor S, Peake S, Chapman M, Bellomo R. 2022-2023. Title: TARGET Protein: The effect of augmented enteral protein administered to critically ill adults on clinical outcomes. Intensive Care Foundation. Value: $100,000
Deane A, Chapman M, Peake S, Chapple L, Presneill J, Bellomo R, Young P, Ridley E, Karahalios E, Tran-Duy A. 2022-2025. Title: Augmenting dietary protein during critical illness: A cluster cross-sectional double cross-over clinical trial. MRFF Rare Cancers Rare Diseases Unmet Need. Value: $1,992,218
Sierp EJ, Chapple LS, Kleinig T, Gardiner E. 2022. Title: The benefits of nasal bridle use in stroke patients: A before and after study. Royal Adelaide Hospital Allied Health, Pharmacy and Nursing Clinical Research Grant. Value: $35,000
Chapple LS. 2022. TARGET Protein Cluster Randomised Controlled Trial. Industry sponsored grant, Nutricia Australia. Value: $290,883
Chapple L, Jones K, Horowitz M, Viner-Smith E. 2021. Title: Phillips Lumify linear array transducer ultrasound probe and portable tablet. AMS/Biomed Small Equipment Funding Award. Value: $7,800
Nadkarni A, Besic N, Micik S, Chapple L, Farquharson M, Reddi B. 2021-2022. Title: Rationalising arterial blood gas sampling in the ICU. South Australian Blood Management Council. Value: $50,000
Jones K, Wu T, Rayner C, Marathe C, Chapple L, Horowitz M. 2021. LOGIQ E10 Ultrasound system- Portable 3D ultrasound device and software. University of Adelaide Faculty of Health and Medical Sciences Research Infrastructure Funding Award. Value: $130,328
Crane R, Chapple L. 2021. Dietitians Association Small Grant. Title: Views of nutrition in patients with scleroderma and their treating physicians: The VENUS study. Value: $5000
Kouw IWK, Chapple L, Summers M, Chapman M, Jones K, Horowitz M. 2021. Diabetes Australia. Title: The effect of enteral feeding pattern on glycaemic control and gastrointestinal function in critically ill patients. Value: $49,826
Gallagher J, Chapple L, Viner-Smith E, Chapman M, Crane R. 2021. Royal Adelaide Hospital Allied Health Grant. Title: Measuring energy expenditure in long-stay intensive care unit patients (MEELS-ICU). Value: $30,000
Perriam A, Kouw I, Chapple L, Heilbronn L, McEwen S, O’Connor S. 2021. Royal Adelaide Hospital Allied Health Grant. Title: Day and night rhythms in critically ill patients. Value: $30,000
Kouw I, Chapple L, Chapman M, Horowitz M, Jones K, Summers M. 2020. American Society of Parenteral and Enteral Nutrition. Title: The effect of enteral feeding pattern on glycemic control and gastrointestinal function in critically ill patients. Value: $US10,000
Konstantopoulos P, Chapple L, Yeung D, Corsini N. 2020. Royal Adelaide Hospital Allied Health Grant. Project title: Understanding nutritional requirements in patients undergoing haematological stem cell transplant (SCT) to improve clinical and patient-centred outcomes: A pilot study. Value: $29,699
Chapple L, Reddi B, Ridley E, Kemp P, Chapman M. 2019. Intensive Care Foundation, MUSCLE health in response to augmented PROtein delivery in critically ill patients (The MUSCLE-PRO study) Value: $24,494
Kurmis R, Gauro J, Vale E, Chapple L, Yandell R, Dowling S, Hill A, Greenwood J. 2019. Allied Health Research Collaboration (SA Health, University of South Australia, The Hospital Research Foundation), Determination of nutritional requirements for severe burn injury patients requiring application of Novosorb Biodegradable Temporising Matrix using indirect calorimetry: A pilot study. Value: $26,000
Chapple L. National Health and Medical Research Council Early Career Fellowship 2019-2022. Optimal protein dose to attenuate muscle atrophy, improve functional recovery and increase survival in critically ill patients. Value: $327,192
Jones KL, Chapman M, Horowitz M, Chapple L, Marathe C. 2018. University of Adelaide, Faculty of Health and Medical Sciences (2018 Research Infrastructure Funding Award) - Project title: Digirad/ERGO Portable Gamma Camera for the scintigraphic measurement of gastric emptying in ‘high-risk’ clinical research. Value: $136,784
Jones KL, Chapman M, Horowitz M, Chapple L, Marathe C. 2018. The Ian Potter Foundation - Project title: Digirad/ERGO Portable Gamma Camera for the scintigraphic measurement of gastric emptying in ‘high-risk’ clinical research. Value: $200,000
Jones KL, Chapman M, Horowitz M, Chapple L, Marathe C. 2018. The Hospital Research Foundation - Project title: Digirad/ERGO Portable Gamma Camera for the scintigraphic measurement of gastric emptying in ‘high-risk’ clinical research. Value: $150,000
Chapple L. The Hospital Research Foundation Project Grant, 2019-2020. Value: $240,000
Chapple L, Weinel L, Summers M, O’Connor S, Horowitz M, Chapman M. 2018. Royal Adelaide Hospital Clinical Project Grant, Nutrient regulation in survivors of critical illness. Value: $48,425
Sierp E, Chapple L, Yandell R, Kurmis R, Chapman M. 2018. Royal Adelaide Hospital Allied Health Grant, Factors that influence severity and timing of gastrointestinal motility in critically ill burn patients. Value: $26,618
Chapple L, Chapman M, Summers M, Jones K, Deane A. 2018. American Society of Parenteral and Enteral Nutrition. The effect of standard versus energy dense feeds on gastric emptying and glucose metabolism in critically ill patients. Value: $25,000 USD
Chapman M, Deane A, Soenen S, van Loon L, Jones K, Chapple L. 2018-2020. National Health and Medical Research Council Project Grant (APP1144496), Protein Absorption and Kinetics in Critical Illness. Value: $1,233,268
Chapple L, Summers M, Weinel L, Chapman M. 2017 Royal Adelaide Hospital Clinical Project Grant. Resolution of Elements Influencing Nutritional STatus After criTical illnEss (REINSTATE trial). Value: $49,959
Ridley E, Chapple L, Davies A, Deane A, Hodgson C, Cooper J, Bailey M. 2017. Baxter Healthcare Corporation, Global Scientific Review Council. Intensive nutrition in critically ill adults: A pilot randomised controlled study. Value: $2,400,000
Chapman M, Deane A, Soenen S, Chapple L. 2016. The University of Adelaide Investment for Success NHMRC Near Miss Grant: Ultrasound probe for Measurement of muscle thickness. Value: $10,080
Chapman M, Deane A, Soenen S, Van Loon L, Jones K, Chapple L, Yandell R, O’Connor S, Horowitz M, Lange K. 2016. Royal Adelaide Hospital NHMRC Near Miss Grant. Protein absorption and kinetics in critical illness. Value: $57,205
Chapple L, Summers M, Deane A, Chapman M. 2016. Australasian Society of Parenteral and Enteral Nutrition (AuSPEN). Long-term effects of critical illness on energy intake, appetite, gastric emptying and appetite-regulating hormones in adult survivors of intensive care unit admission. Value: $20,000
Costello L, Chapman M, Deane A. 2015. Royal Adelaide Hospital Clinical Project Grant Award. Quantification of muscle size and function in response to a randomised nutritional intervention in critically ill patients. Value: $46,198
Chapman M, Deane A, Soenen S, Van Loon L, Costello L. 2015. Royal Adelaide Hospital Clinical Project Grant Award. The effect of protein hydrolysis on the rate and extent of protein absorption and muscle uptake in critically ill patients. Value: $49,560
Costello L, Chapman M. 2014. Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Small Project Grant. The provision of energy and protein in adults with moderate-severe traumatic brain injury (PEP-TBI). Value: $10,000
Chapman M, Costello L. 2014. Neurosurgical Research Foundation grant. The provision of energy and protein after traumatic brain injury (PEP-TBI). Value: $28,150
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2024 Principal Supervisor Improved recovery for survivors of intensive care. Doctor of Philosophy Doctorate Full Time Mrs Simone Dafoe 2024 Principal Supervisor Optimising nutrition care following pelvic exenteration surgery. Doctor of Philosophy Doctorate Full Time Ms Alice Jay 2023 Principal Supervisor Mitigating the short and long-term complications of stress hyperglycaemia Doctor of Philosophy Doctorate Full Time Mr Aniket Nadkarni 2022 Principal Supervisor Enteral protein delivery in the critically ill Doctor of Philosophy Doctorate Full Time Mr Matthew Summers 2021 Principal Supervisor Critical care nutrition throughout the hospital continuum Doctor of Philosophy Doctorate Full Time Miss Elizabeth Viner Smith -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2018 - 2022 Co-Supervisor Nutrient delivery, absorption, and utilisation in health and illness Doctor of Philosophy Doctorate Full Time Dr Tejaswini Arunachala Murthy -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2022 - 2023 Principal Supervisor Nutrition in non-invasive ventilation in critical illness Flinders University - Honours Full Time Kaitlyn Page 2020 - ongoing Principal Supervisor Protein prescription and delivery in critically ill adults Flinders University - Honours - Gemma Lyons 2019 - ongoing Principal Supervisor Muscle wasting in response to augmented protein delivery. Royal Adelaide Hospital - Honours - Adam Vanson 2019 - ongoing Principal Supervisor Resolution of delayed gastric emptying, reduced glucose absorption and hypercatabolism in survivors of critical illness. Royal Adelaide Hospital - Honours - James Whitehead 2018 - ongoing Principal Supervisor Point of care albumin/creatinine testing in critical illness Royal Adelaide Hospital Health Science Student Research Project Other - Olivia Bellas 2018 - ongoing Principal Supervisor Point of care albumin/creatinine testing in critical illness Royal Adelaide Hospital Health Science Student Research Project Other - Zoe Tammita 2018 - ongoing Principal Supervisor Point of care albumin/creatinine testing in critical illness Royal Adelaide Hospital Health Science Student Research Project Other - Keyi Feng -
Mentoring
Date Topic Location Name 2018 - ongoing Point Prevalence Nutrition Program in critical illness ICU, Royal Adelaide Hospital Dr Anneleen Neuts
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Committee Memberships
Date Role Committee Institution Country 2022 - ongoing Member Faculty of Health Career Development Committee University of Adelaide Australia 2021 - ongoing Chair American Society of Parenteral and Enteral Nutrition Research Section Committee American Society of Parenteral and Enteral Nutrition Australia 2020 - ongoing Member Faculty of Health Research Committee University of Adelaide Australia 2019 - 2022 Member European Society of Parenteral and Enteral Nutrition Early Career Faculty Member European Society of Clinical Nutrition and Metabolism Australia 2019 - ongoing Member Australian and New Zealand Intensive Care Society Clinical Trials Group Novice Investigator Group Australian and New Zealand Intensive Care Society Clinical Trials Group Australia 2019 - ongoing - Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Conference Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) - 2018 - ongoing Member - Metabolism And Nutrition for Intensive Care (MANIC) Australia 2017 - ongoing Member American Society of Parenteral and Enteral Nutrition Research Section committee American Society of Parenteral and Enteral Nutrition Research Section Australia 2017 - ongoing Member Critical Care Professional Certificate Steering Dietitians Association of Australia (DAA) Australia 2016 - ongoing Member National Member Engagement and Development Advisory Committee Dietitians Association of Australia (DAA) Australia 2015 - 2017 Chair SA Engagement and Development Committee Dietitians Association of Australia (DAA) Australia 2015 - 2017 Member Education and Professional Development Advisory Committee Dietitians Association of Australia (DAA) Australia 2015 - ongoing Member South Australia Allied and Scientific Health Professional Associations Committee South Australia Allied and Scientific Health Professional Associations Committee Australia 2014 - 2016 Secretary SA Branch Executive Dietitians Association of Australia (DAA) Australia 2013 - 2014 Secretary ACT Branch Executive Dietitians Association of Australia (DAA) Australia -
Memberships
Date Role Membership Country 2021 - ongoing Member Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Scientific Committee Australia 2019 - ongoing Member European Society of Parenteral and Enteral Nutrition Australia 2019 - ongoing Member Australian and New Zealand Intensive Care Society Intensive Care Clinical Trials Group Australia 2018 - ongoing Council Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Australia 2015 - ongoing Member American Society of Parenteral and Enteral Nutrition Australia 2014 - ongoing Member Australasian Society of Parenteral and Enteral Nutrition Australia 2014 - ongoing Member European Society of Parenteral and Enteral Nutrition Australia 2012 - ongoing Member DAA, Accredited Practising Dietitian Australia -
Consulting/Advisories
Date Institution Department Organisation Type Country 2021 - 2021 American Society of Parenteral and Enteral Nutrition Journal of Parenteral and Enteral Nutrition Health services and related Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2022 - ongoing Editor Australian Critical Care Journal Australian Critical Care Journal Australia 2020 - ongoing Editor Frontiers in Endocrinology – Gut Endocrinology Frontiers in Endocrinology Australia 2020 - ongoing Member Gold Coast Health Research Grant Scheme Gold Coast Health Australia 2019 - 2022 Associate Editor Clinical nutrition ESPEN Clinical Nutrition ESPEN Australia 2019 - ongoing Associate Editor Clinical Nutrition ESPEN Clinical Nutrition ESPEN Australia -
Event Participation
Date Event Name Event Type Institution Country 2021 - ongoing Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) Conference Conference Australasian Society of Parenteral and Enteral Nutrition (AuSPEN) - 2021 - ongoing NTense Dinner Meeting Conference Fresenius Kabi Australia 2016 - ongoing Tracer Methodology in Metabolism Workshop European Society for Clinical Nutrition and Metabolism United Kingdom 2016 - ongoing Extended scope of practice: ‘Dietitians: Working Outside the Box’ Function Dietitians Association of Australia SA Branch - -
Presentation
Date Topic Presented at Institution Country 2017 - ongoing Neurological Conditions Master of Nutrition and Dietetics University of Canberra Australia
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