David Torpy
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Torpy is Senior Endocrinologist and Deputy Director, Endocrine and Metabolic Unit, Royal Adelaide Hospital. He is also Professor of Medicine at the University of Adelaide School of Medicine. His research interests predominantly involve studies of the hypothalamic-pituitary-adrenal axis and stress. Recent specific areas have included corticosteroid-binding globulin (CBG) genetic variants and their effect on the stress response, immune-HPA interactions involving CBG in inflammatory states, adrenal function in septic shock, maternal cortisolaemia in complicated pregnancies, inherited forms of adrenal dysfunction causing Cushing’s, adrenocortical carcinoma, opioids and adrenal function, the stress axis in hypoglycaemia unawareness, and cortisone dosing and well-being in Addison’s disease.
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Appointments
Date Position Institution name 2012 - ongoing Professor, Discipline of Medicine University of Adelaide 2011 - ongoing Deputy Director, Endocrine & Metabolic Unit Royal Adelaide Hospital, Adelaide 2002 - ongoing Senior Consultant Endocrinologist Royal Adelaide Hospital 2002 - 2012 Associate Professor, Discipline of Medicine University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2012 Award Prof Derek Frewin AO Citation for Clinical Teaching – Recognised by MBBS students, School of Medicine University of Adelaide Australia - -
Education
Date Institution name Country Title 1996 University of Queensland Australia PhD 1991 Royal Australasian College of Physicians Australia Fellowship of the Royal Australasian College of Physicians 1984 University of Adelaide Australia MBBS -
Postgraduate Training
Date Title Institution Country 1995 - 1998 PhD University of Queensland Australia -
Certifications
Date Title Institution name Country 1993 ECFMG Certification Educational Commission for Foreign Medical Graduates United States -
Research Interests
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Journals
Year Citation 2025 Rushworth, R. L., Falhammar, H., & Torpy, D. J. (2025). Adrenal Crisis and Adrenal Insufficiency Admissions in Patients 30–59 Years: Contribution of Psychosocial Factors. Clinical Endocrinology, 102(3), 245-254.
2025 Willemsen, A. L., Torpy, D. J., De Sousa, S. M. C., Falhammar, H., & Rushworth, R. L. (2025). 17α-Hydroxylase/17,20-lyase Deficiency (17-OHD): A Meta-analysis of Reported Cases. Journal of Clinical Endocrinology and Metabolism, 110(4), e1261-e1271.
2025 Lee, J. H., Sumer-Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567, 8 pages.
Scopus1 Europe PMC12025 Torpy, H., Chau, T. H., Chatterjee, S., Chernykh, A., Torpy, D. J., Meyer, E. J., & Thaysen-Andersen, M. (2025). Impact of different pathogen classes on the serum N-glycome in septic shock. BBA Advances, 7, 100138-1-100138-9.
2025 Candy, N. G., Mignone, E., Quick, E., Koszyca, B., Brown, A., Chapman, I. M., . . . De Sousa, S. M. C. (2025). The role of BRAF testing of Rathke's cleft cysts to identify missed papillary craniopharyngioma.. Pituitary, 28(1), 30.
Scopus12025 Ramsay, S. D., Nenke, M. A., Meyer, E. J., Torpy, D. J., & Young, R. L. (2025). Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy. Frontiers in Endocrinology, 16, 1508848-1-1508848-16.
Scopus12025 Chernykh, A., Sumer-Bayraktar, Z., Lee, J. H., Meyer, E. J., Torpy, D. J., & Thaysen-Andersen, M. (2025). RCL glycosylation of serum corticosteroid-binding globulin: implications in cortisol delivery and septic shock. Glycobiology, 35(4), cwaf013-1-cwaf013-10.
2024 Peel, A., Rushworth, R. L., & Torpy, D. J. (2024). Novel agents to treat adrenal insufficiency: findings of preclinical and early clinical trials. Expert Opinion on Investigational Drugs, 33(2), 115-126.
Scopus4 Europe PMC32024 Nowell, A., Torres, S. J., Hall, S. J., Keske, M. A., Torpy, D. J., Parker, L., . . . Turner, A. I. (2024). Is high salt intake inducing obesity via production of cortisol? A novel working hypothesis and pilot study. European Journal of Nutrition, 63(4), 1315-1327.
Europe PMC12024 De Sousa, S. M. C., Jukes, A. K., Candy, N. G., Chapman, I. M., Torpy, D. J., Shivalingam, B., . . . Santoreneos, S. (2024). Tumour fibrosis in dopamine agonist-exposed prolactinomas is a diminishing concern.. Nat Rev Endocrinol, 20(5), 314.
Scopus3 Europe PMC12024 De Sousa, S. M. C., Mccormack, A., Orsmond, A., Shen, A., Yates, C. J., Clifton-Bligh, R., . . . Scott, H. S. (2024). Increased Prevalence of Germline Pathogenic CHEK2 Variants in Individuals With Pituitary Adenomas. Journal of Clinical Endocrinology and Metabolism, 109(11), 2720-2728.
Scopus3 Europe PMC22024 Torpy, D. J., & Lim, W. T. (2024). Glucocorticoid-induced adrenal suppression: physiological basis and strategies for glucocorticoid weaning. Medical Journal of Australia, 220(10), 1 page.
Scopus12024 Ramadhany, P., Trần-Phú, T., Yuwono, J. A., Ma, Z., Han, C., Nguyen, T. K. A., . . . Daiyan, R. (2024). Triggering C‒N Coupling on Metal Oxide Nanocomposite for the Electrochemical Reduction of CO₂ and NOₓ⁻ to Formamide. Advanced Energy Materials, 14(32), 2401786-1-2401786-13.
Scopus182024 Maiden, M. J., Torpy, D. J., Ludbrook, G. L., Clarke, I. J., Chacko, B., Nash, C. H., . . . Kuchel, T. R. (2024). Triiodothyronine supplementation in a sheep model of intensive care. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 28(2), 7 pages.
2024 Lee, J. H., Meyer, E. J., Nenke, M. A., Lightman, S. L., & Torpy, D. J. (2024). Cortisol, Stress, and Disease-Bidirectional Associations; Role for Corticosteroid-Binding Globulin?. Journal of Clinical Endocrinology and Metabolism, 109(9), 2161-2172.
Scopus12024 Clarke, B. M., Kireta, S., Johnston, J., Christou, C., Greenwood, J. E., Hurtado, P. R., . . . Torpy, D. J. (2024). In Vivo Formation of Adrenal Organoids in a Novel Porcine Model of Adrenocortical Cell Transplantation. Endocrinology United States, 165(8), 19 pages.
Scopus1 Europe PMC22024 Hayes, A. G., Stowasser, M., Umapathysivam, M. M., Falhammar, H., & Torpy, D. J. (2024). Approach to the Patient: Reninoma. Journal of Clinical Endocrinology and Metabolism, 109(2), e809-e816.
Scopus4 WoS1 Europe PMC42024 Ragnarsson, O., Juhlin, C. C., Torpy, D. J., & Falhammar, H. (2024). A clinical perspective on ectopic Cushing's syndrome. Trends in Endocrinology and Metabolism, 35(4), 347-360.
Scopus18 Europe PMC112023 Candy, N. G., Jukes, A. K., Van Der Veken, J., Torpy, D. J., Vrodos, N., Santoreneos, S., . . . Psaltis, A. J. (2023). The Learning Curve for Endoscopic Endonasal Transsphenoidal Pituitary Surgery: Evaluating Endocrine Outcomes.. J Clin Neurosci, 120, 14-22.
Scopus2 Europe PMC12023 De Sousa, S. M. C., Wu, K. H. C., Colclough, K., Rawlings, L., Dubowsky, A., Monnik, M., . . . Torpy, D. J. (2023). Identification of monogenic diabetes in an Australian cohort using the Exeter maturity-onset diabetes of the young (MODY) probability calculator and next-generation sequencing gene panel testing. Acta Diabetologica: an international journal devoted to the study of clinical and experimental diabetes and metabolism, 61(2), 181-188.
Scopus1 Europe PMC12023 Torpy, D. J., & Lim, W. T. (2023). Glucocorticoid-induced adrenal suppression: physiological basis and strategies for glucocorticoid weaning. Medical Journal of Australia, 219(10), 444-447.
Scopus42023 Ganni, R., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2023). Response to Letter to the Editor From Yu: “Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis”. Journal of Clinical Endocrinology and Metabolism, 108(10), e1162.
Scopus12023 Rushworth, R. L., Falhammar, H., & Torpy, D. J. (2023). Factors underlying a disproportionate increase in hospital admissions for adrenal insufficiency in women aged 20-29 years. Frontiers in Endocrinology, 14, 8 pages.
Scopus2 Europe PMC12023 De Sousa, S. M. C., Shen, A., Yates, C. J., Clifton-Bligh, R., Santoreneos, S., King, J., . . . Scott, H. S. (2023). <i>PAM</i> variants in patients with thyrotrophinomas, cyclical Cushing's disease and prolactinomas. FRONTIERS IN ENDOCRINOLOGY, 14, 10 pages.
Europe PMC32023 Lee, J. H., & Torpy, D. J. (2023). Adrenal insufficiency in pregnancy: Physiology, diagnosis, management and areas for future research. Reviews in Endocrine and Metabolic Disorders, 24(1), 57-69.
Scopus8 WoS2 Europe PMC72023 Umapathysivam, M. M., Morgan, B., Bischoff, C., Hayes, A., Wilks, M., Stowasser, M., & Torpy, D. J. (2023). Intraprocedural cortisol testing improves adrenal vein cannulation success and diagnostic accuracy in assessment of primary aldosteronism, in a medium throughput centre. Journal of Human Hypertension, 37(9), 783-787.
Scopus8 WoS2 Europe PMC52023 Heath, M., Torpy, D. J., & Rushworth, R. L. (2023). An analysis of the utilisation of medical identification jewellery among children and young adults with type 1 diabetes mellitus in Australia. Endocrine, 79(1), 72-79.
Scopus12023 Graves, L. E., Torpy, D. J., Coates, P. T., Alexander, I. E., Bornstein, S. R., & Clarke, B. (2023). Future Directions for Adrenal Insufficiency: Cellular Transplantation and Genetic Therapies. Journal of Clinical Endocrinology and Metabolism, 108(6), 1273-1289.
Scopus9 WoS2 Europe PMC72023 Hayes, A. G., Shirazi, M. G., Thiyagarajah, A., Torpy, D. J., & De Sousa, S. M. C. (2023). Cabergoline-associated valvulopathy of the tricuspid valve in the treatment of prolactinoma. Endocrine Oncology, 3(1), e220086.
2023 Lee, J. H., Meyer, E. J., Nenke, M. A., Falhammar, H., & Torpy, D. J. (2023). Corticosteroid-binding globulin (CBG): spatiotemporal distribution of cortisol in sepsis. Trends in Endocrinology and Metabolism, 34(3), 181-190.
Scopus12 WoS2 Europe PMC72023 Lee, J. H., Nenke, M. A., Flabouris, K., Torpy, D. J., & Meyer, E. J. (2023). Plasma corticosteroid-binding globulin concentrations are preserved in mild cirrhosis. Liver International, 43(3), 740-741.
Scopus12023 Rushworth, R. L., & Torpy, D. J. (2023). The Changing Epidemiology of Adrenal Insufficiency: Iatrogenic Factors Predominate. Journal of the Endocrine Society, 7(3), 13 pages.
Scopus12 WoS1 Europe PMC92023 Ganni, R., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2023). Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis. Journal of Clinical Endocrinology and Metabolism, 108(9), E885-E892.
Scopus5 WoS2 Europe PMC12022 Raftopulos, N. L., Torpy, D. J., & Louise Rushworth, R. (2022). Epidemiology of acute pancreatitis in Australia from 2007–2019. ANZ Journal of Surgery, 92(1-2), 92-98.
Scopus5 WoS4 Europe PMC32022 Hayes, A. G., Rushworth, R. L., & Torpy, D. J. (2022). Risk assessment, diagnosis, and treatment of cancer treatment-related adrenal insufficiency. Expert Review of Endocrinology and Metabolism, 17(1), 21-33.
Scopus5 WoS3 Europe PMC42022 Saranapala, D. M. M. K., Baranoff, J., Rushworth, R. L., Westley, I., Collins, K., Burke, A. L. J., . . . Torpy, D. J. (2022). The effect of cognitive behavioral stress management on perceived stress, biological stress markers and weight loss/regain, from a diet-induced weight loss program: A randomized controlled trial. Comprehensive Psychoneuroendocrinology, 10, 1-9.
Scopus3 Europe PMC12022 Meyer, E. J., Nenke, M. A., Davies, M. L., Chapman, M., Rankin, W., Rushworth, R. L., & Torpy, D. J. (2022). Corticosteroid-Binding Globulin Deficiency Independently Predicts Mortality in Septic Shock. Journal of Clinical Endocrinology and Metabolism, 107(6), 1636-1646.
Scopus16 WoS7 Europe PMC102022 Wu, D., Bampton, T. J., Scott, H. S., Brown, A., Kassahn, K., Drogemuller, C., . . . Coates, P. T. (2022). The clinical and genetic features of hereditary pancreatitis in South Australia.. Medical Journal of Australia, 216(11), 578-582.
Scopus4 Europe PMC22022 Rushworth, R. L., Chrisp, G. L., Bownes, S., Torpy, D. J., & Falhammar, H. (2022). Adrenal crises in adolescents and young adults. Endocrine, 77(1), 1-10.
Scopus14 WoS8 Europe PMC82022 Hayes, A. G., Umapathysivam, M. M., & Torpy, D. J. (2022). Accidental exposure to glimepiride from adulterated medication resulting in severe hypoglycaemia. Endocrinology Diabetes and Metabolism Case Reports, 2022(1), 4 pages.
Scopus12022 Lao, L., Bourdeau, I., Gagliardi, L., He, X., Shi, W., Hao, B., . . . Wu, J. (2022). ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia. Nucleic Acids Research, 50(11), 6343-6367.
Scopus22 WoS2 Europe PMC172022 Chrisp, G. L., Quartararo, M., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2022). Trends in hospital admissions for adrenal insufficiency in adolescents and young adults in the 21st century. Frontiers in Endocrinology, 13, 11 pages.
Scopus10 WoS1 Europe PMC62022 Meyer, E. J., Nenke, M. A., Davies, M. L., Chapman, M., Rankin, W., Rushworth, R. L., & Torpy, D. J. (2022). Erratum to: "Corticosteroid-Binding Globulin Deficiency Independently Predicts Mortality in Septic Shock" (The Journal of Clinical Endocrinology and Metabolism (2022) DOI: 10.1210/clinem/dgac035). Journal of Clinical Endocrinology and Metabolism, 107(8), E3547.
2022 Hensman, C. J., Gooley, J. L., Januszewski, A. S., Lee, M. H., MacIsaac, R. J., Boston, R. C., . . . Jenkins, A. J. (2022). Insulin antibodies are prevalent in adults with type 1 diabetes referred for islet cell transplantation and are modified by islet transplantation and immunosuppression: an Australian experience. Internal Medicine Journal, 52(8), 1434-1436.
2021 Jalleh, R., & Torpy, D. J. (2021). The Emerging Role of Copeptin.. The Clinical biochemist. Reviews, 42(1), 17-25.
Europe PMC182021 Bampton, T. J., Holmes-Walker, D. J., Drogemuller, C. J., Radford, T., Anderson, P., Etherton, C., . . . Australian Islet Consortium. (2021). Australian experience with total pancreatectomy with islet autotransplantation to treat chronic pancreatitis. ANZ Journal of Surgery, 91(12), 2663-2668.
Scopus4 WoS1 Europe PMC52021 Bichard, L. K., Rushworth, R. L., & Torpy, D. J. (2021). Flash Glucose Monitoring Compared to Capillary Glucose Levels in Patients With Diabetic Ketoacidosis: Potential Clinical Applications. Endocrine Practice, 27(8), 813-818.
Scopus8 WoS4 Europe PMC62021 Lubomski, A., Falhammar, H., Torpy, D. J., & Rushworth, R. L. (2021). The epidemiology of primary and secondary adrenal malignancies and associated adrenal insufficiency in hospitalised patients: an analysis of hospital admission data, NSW, Australia. BMC Endocrine Disorders, 21(1), 10 pages.
Scopus5 WoS3 Europe PMC32021 Meyer, E. J., Spangenberg, L., Ramírez, M. J., De Sousa, S. M. C., Raggio, V., & Torpy, D. J. (2021). CBG Montevideo: A Clinically Novel SERPINA6 Mutation Leading to Haploinsufficiency of Corticosteroid-binding Globulin. Journal of the Endocrine Society, 5(9), 8 pages.
Scopus7 WoS1 Europe PMC32021 Rushworth, R. L., Goubar, T., Ostman, C., McGrath, S., & Torpy, D. J. (2021). Interaction between hypotension and age on adrenal crisis diagnosis. Endocrinology Diabetes and Metabolism, 4(2), 5 pages.
Scopus3 WoS2 Europe PMC42021 Chatterjee, S., Kawahara, R., Tjondro, H. C., Shaw, D. R., Nenke, M. A., Torpy, D. J., & Thaysen-Andersen, M. (2021). Serum N-glycomics stratifies bacteremic patients infected with different pathogens. Journal of Clinical Medicine, 10(3), 1-18.
Scopus17 WoS5 Europe PMC122021 Rushworth, R. L., Gouvoussis, N., Goubar, T., Maguire, A., Munns, C. F., Neville, K. A., & Torpy, D. J. (2021). Acute illness in children with secondary adrenal insufficiency. Clinical Endocrinology, 94(6), 913-919.
Scopus6 WoS2 Europe PMC62021 Chrisp, G. L., Quartararo, M., Torpy, D. J., Falhammar, H., & Rushworth, R. L. (2021). Use of medical identification jewellery in children and young adults with adrenal insufficiency in Australia. Endocrine, 72(2), 539-545.
Scopus7 WoS3 Europe PMC82021 Hamblin, P. S., Yeap, B. B., & Torpy, D. J. (2021). Sepsis and adrenal insufficiency: a potentially lethal combination. Medical Journal of Australia, 214(7), 334-334.e1.
2021 Hahner, S., Ross, R. J., Arlt, W., Bancos, I., Burger-Stritt, S., Torpy, D. J., . . . Quinkler, M. (2021). Adrenal insufficiency. Nature Reviews Disease Primers, 7(1), 19.
Scopus99 WoS38 Europe PMC742020 De Sousa, S. M. C., Baranoff, J., Rushworth, R. L., Butler, J., Sorbello, J., Vorster, J., . . . Torpy, D. J. (2020). Impulse control disorders in dopamine agonist-treated hyperprolactinemia: prevalence and risk factors.. The Journal of clinical endocrinology and metabolism, 105(3), 108-118.
Scopus57 WoS24 Europe PMC322020 Dean, B., Chrisp, G. L., Quartararo, M., Maguire, A. M., Hameed, S., King, B. R., . . . Rushworth, R. L. (2020). P450 oxidoreductase deficiency: A systematic review and meta-analysis of genotypes, phenotypes and their relationships.. The Journal of clinical endocrinology and metabolism, 105(3), e43-E54.
Scopus19 WoS9 Europe PMC132020 De Sousa, S. M. C., Manavis, J., Feng, J., Wang, P., Schreiber, A. W., Scott, H. S., & Torpy, D. J. (2020). A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease. BMC Endocrine Disorders, 20(1), 6 pages.
Scopus6 WoS4 Europe PMC52020 Chrisp, G. L., Torpy, D. J., Maguire, A. M., Quartararo, M., Falhammar, H., King, B. R., . . . Rushworth, R. L. (2020). The effect of patient-managed stress dosing on electrolytes and blood pressure in acute illness in children with adrenal insufficiency. Clinical Endocrinology, 93(2), 97-103.
Scopus7 WoS5 Europe PMC42020 Mortimer, B., Naganur, V. D., Satouris, P., Greenfield, J. R., Torpy, D. J., & Rushworth, R. L. (2020). Acute illness in patients with concomitant Addison's disease and type 1 diabetes mellitus: Increased incidence of hypoglycaemia and adrenal crises. Clinical Endocrinology, 93(2), 104-110.
Scopus9 WoS5 Europe PMC72020 Hodyl, N. A., Stark, M. J., Meyer, E. J., Lewis, J. G., Torpy, D. J., & Nenke, M. A. (2020). High binding site occupancy of corticosteroid-binding globulin by progesterone increases fetal free cortisol concentrations. European Journal of Obstetrics and Gynecology and Reproductive Biology, 251, 129-135.
Scopus5 WoS3 Europe PMC32020 Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2020). Adrenal crises in older patients. The Lancet Diabetes and Endocrinology, 8(7), 628-639.
Scopus34 WoS19 Europe PMC252020 Bichard, L. K., & Torpy, D. J. (2020). Diabetes insipidus complicating apoplexy during pregnancy: the potential use of copeptin. Internal Medicine Journal, 50(7), 877-879.
Scopus5 WoS2 Europe PMC12020 Clarke, B., Loudovaris, T., Radford, T., Drogemuller, C., Coates, P. T., & Torpy, D. (2020). Ambulatory intravenous insulin and islet cell transplantation to treat severe type III insulin hypersensitivity in a patient with type 1 diabetes mellitus. Clinical Case Reports, 8(12), 2758-2761.
Scopus1 Europe PMC22020 Meyer, E. J., Torpy, D. J., Chernykh, A., Thaysen-Andersen, M., Nenke, M. A., Lewis, J., . . . Polyak, S. W. (2020). Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin. Protein Science, 29(12), 2495-2509.
Scopus10 WoS5 Europe PMC82020 De Sousa, S. M. C., Toubia, J., Hardy, T. S. E., Feng, J., Wang, P., Schreiber, A. W., . . . Torpy, D. J. (2020). Aberrant Splicing of SDHC in Families With Unexplained Succinate Dehydrogenase-Deficient Paragangliomas. Journal of the Endocrine Society, 4(12), 1-12.
Scopus12 WoS6 Europe PMC92020 Bayar, E., Bennett, P. R., Chan, D., Sykes, L., & MacIntyre, D. A. (2020). The pregnancy microbiome and preterm birth. Seminars in Immunopathology, 42(4), 487-499.
Scopus101 Europe PMC812019 Brown, R. G., Chan, D., Terzidou, V., Lee, Y. S., Smith, A., Marchesi, J. R., . . . Bennett, P. R. (2019). Prospective observational study of vaginal microbiota pre- and post-rescue cervical cerclage. BJOG an International Journal of Obstetrics and Gynaecology, 126(7), 916-925.
Scopus47 Europe PMC352019 Barthel, A., Benker, G., Berens, K., Diederich, S., Manfras, B., Gruber, M., . . . Bornstein, S. R. (2019). An Update on Addison's Disease. Experimental and Clinical Endocrinology and Diabetes, 127(2-3), 165-170.
Scopus71 WoS41 Europe PMC392019 Webster, A. C., Hedley, J. A., Anderson, P. F., Hawthorne, W. J., Radford, T., Drogemuller, C., . . . Olakkengil, S. (2019). Australia and New Zealand islet and pancreas transplant registry annual report 2018—islet donations, islet isolations, and islet transplants. Transplantation Direct, 5(2), 9 pages.
Scopus5 WoS3 Europe PMC32019 Rushworth, R. L., Chrisp, G. L., & Torpy, D. J. (2019). The use of medical identification jewellery in adults with adrenal insufficiency in Australia. Clinical Endocrinology, 91(1), 41-47.
Scopus8 WoS7 Europe PMC52019 Philpott, H., Dougherty, M., Torpy, D., & Dellon, E. (2019). Letter: reassuringly normal response to ACTH in children treated with swallowed topical corticosteroids for eosinophilic oesophagitis – authors’ reply. Alimentary Pharmacology and Therapeutics, 49(12), 1539.
2019 Tallis, P. H., Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2019). Adrenal insufficiency due to bilateral adrenal metastases – A systematic review and meta-analysis. Heliyon, 5(5), 8 pages.
Scopus30 WoS21 Europe PMC262019 De Sousa, S. M. C., Saleem, M., Rankin, W., & Torpy, D. J. (2019). Serum prolactin overestimation and risk of misdiagnosis. ENDOCRINOLOGY DIABETES & METABOLISM, 2(3), 4 pages.
Europe PMC42019 Meyer, E. J., Nenke, M. A., Rankin, W., Lewis, J. G., Konings, E., Slager, M., . . . Torpy, D. J. (2019). Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality. Clinical Endocrinology, 90(1), 232-240.
Scopus12 WoS9 Europe PMC72019 Maiden, M. J., & Torpy, D. J. (2019). Thyroid Hormones in Critical Illness. Critical Care Clinics, 35(2), 375-388.
Scopus64 WoS42 Europe PMC382019 Goubar, T., Torpy, D. J., McGrath, S., & Rushworth, R. L. (2019). Prehospital Management of Acute Addison Disease: Audit of Patients Attending a Referral Hospital in a Regional Area.. Journal of the Endocrine Society, 3(12), 2194-2203.
Scopus12 WoS10 Europe PMC92019 Rushworth, R. L., Torpy, D. J., & Falhammar, H. (2019). Adrenal Crisis. Reply. New England Journal of Medicine, 381(22), 2182-2183.
Scopus2 WoS22019 De Sousa, S. M. C., Wang, P. P. S., Santoreneos, S., Shen, A., Yates, C. J., Babic, M., . . . Scott, H. S. (2019). The Genomic Landscape of Sporadic Prolactinomas. Endocrine Pathology, 30(4), 318-328.
Scopus18 WoS8 Europe PMC152019 Louise Rushworth, R., Torpy, D. J., & Falhammar, H. (2019). Adrenal crisis. New England Journal of Medicine, 381(9), 852-861.
Scopus176 WoS101 Europe PMC1182019 Torpy, D. J. (2019). Commentary on article: Adrenal crisis in treated patients with Cushing’s syndrome. European Journal of Endocrinology, 181(4), C13-C15.
Scopus3 WoS2 Europe PMC22018 Chrisp, G. L., Maguire, A. M., Quartararo, M., Falhammar, H., King, B. R., Munns, C. F., . . . Rushworth, R. L. (2018). Variations in the management of acute illness in children with congenital adrenal hyperplasia: An audit of three paediatric hospitals. Clinical Endocrinology, 89(5), 577-585.
Scopus23 WoS20 Europe PMC142018 De Sousa, S. M. C., Hardy, T. S. E., Scott, H. S., & Torpy, D. J. (2018). Genetic testing in endocrinology. Clinical Biochemist Reviews, 39(1), 17-28.
Scopus16 Europe PMC92018 Kalra, S., Sahoo, A., Das, S., Kumar, K. V. S. H., Baliarsinha, A. K., Mohanty, B., . . . Acharya, K. (2018). The Bhubaneswar declaration on sports endocrinology, 2018. Indian Journal of Endocrinology and Metabolism, 22(7), S14-S16.
Scopus2 Europe PMC12018 Lamprecht, A., Sorbello, J., Jang, C., Torpy, D. J., & Inder, W. J. (2018). Secondary adrenal insufficiency and pituitary dysfunction in oral/transdermal opioid users with non-cancer pain. European Journal of Endocrinology, 179(6), 353-362.
Scopus39 WoS31 Europe PMC232018 Crowther, S., Rushworth, R., Rankin, W., Falhammar, H., Phillips, L., & Torpy, D. (2018). Trends in surgery, hospital admissions and imaging for pituitary adenomas in Australia. Endocrine, 59(2), 373-382.
Scopus13 WoS10 Europe PMC102018 Philpott, H., Dougherty, M. K., Reed, C. C., Caldwell, M., Kirk, D., Torpy, D. J., & Dellon, E. S. (2018). Systematic review: adrenal insufficiency secondary to swallowed topical corticosteroids in eosinophilic oesophagitis. Alimentary Pharmacology and Therapeutics, 47(8), 1071-1078.
Scopus59 WoS37 Europe PMC442018 Rushworth, R. L., Chrisp, G. L., & Torpy, D. J. (2018). Glucocorticoid-induced adrenal insufficiency: A study of the incidence in hospital patients and a review of peri-operative management. Endocrine Practice, 24(5), 437-445.
Scopus17 WoS9 Europe PMC102018 Trainer, P. J., Newell-Price, J. D. C., Ayuk, J., Aylwin, S. J. B., Rees, A., Drake, W., . . . Bidlingmaier, M. (2018). A randomised, open-label, parallel group phase 2 study of antisense oligonucleotide therapy in acromegaly. European Journal of Endocrinology, 179(2), 97-108.
Scopus32 WoS21 Europe PMC192018 Rushworth, R., Torpy, D., Stratakis, C., & Falhammar, H. (2018). Adrenal crises in children: perspectives and research directions. Hormone Research in Paediatrics, 89(5), 341-351.
Scopus44 WoS33 Europe PMC302017 De Sousa, S. M. C., McCormack, A. I., McGrath, S., & Torpy, D. J. (2017). Prolactin correction for adequacy of petrosal sinus cannulation may diminish diagnostic accuracy in Cushing's disease. Clinical Endocrinology, 87(5), 515-522.
Scopus21 WoS14 Europe PMC112017 Meyer, E. J., Nenke, M. A., Lewis, J. G., & Torpy, D. J. (2017). Corticosteroid-binding globulin: acute and chronic inflammation. Expert Review of Endocrinology and Metabolism, 12(4), 241-251.
Scopus18 WoS15 Europe PMC142017 De Sousa, S. M. C., Meyer, E. J., Rankin, W., Brautigan, P. J., Burt, M. G., & Torpy, D. J. (2017). Vasculogenic hyperprolactinemia: severe prolactin excess in association with internal carotid artery aneurysms. Pituitary, 20(6), 676-682.
Scopus5 WoS4 Europe PMC42017 Rushworth, R., Chrisp, G., Dean, B., Falhammar, H., & Torpy, D. (2017). Hospitalisation in Children with Adrenal Insufficiency and Hypopituitarism: Is There a Differential Burden between Boys and Girls and between Age Groups?. Hormone Research in Paediatrics, 88(5), 339-346.
Scopus16 WoS14 Europe PMC132017 De Sousa, S. M. C., Stowasser, M., Feng, J., Schreiber, A. W., Wang, P., Hahn, C. N., . . . Gagliardi, L. (2017). ARMC5 is not implicated in familial hyperaldosteronism type II (FH-II). Journal of Human Hypertension, 31(12), 857-859.
Scopus5 WoS1 Europe PMC42017 Rushworth, R., Torpy, D., & Falhammar, H. (2017). Adrenal crises: perspectives and research directions. Endocrine, 55(2), 336-345.
Scopus69 WoS49 Europe PMC452017 Nenke, M. A., Nielsen, S. T., Lehrskov, L. L., Lewis, J. G., Rankin, W., Møller, K., & Torpy, D. J. (2017). Pyrexia’s effect on the CBG-cortisol thermocouple, rather than CBG cleavage, elevates the acute free cortisol response to TNF-α in humans. Stress, 20(2), 183-188.
Scopus6 WoS5 Europe PMC22017 Rushworth, R. L., Bischoff, C., & Torpy, D. J. (2017). Preventing adrenal crises: home-administered subcutaneous hydrocortisone is an option. Internal Medicine Journal, 47(2), 231-232.
Scopus2 WoS2 Europe PMC32017 Du, Y. T., Roberts, A. P., & Torpy, D. J. (2017). Seizure induced by sudden cessation of pregabalin in a patient with chronic kidney disease. BMJ Case Reports, 2017, bcr-2016-219158.
Scopus5 Europe PMC22017 Nenke, M. A., Zeng, A., Meyer, E. J., Lewis, J. G., Rankin, W., Johnston, J., . . . Torpy, D. J. (2017). Differential Effects of Estrogen on Corticosteroid-Binding Globulin Forms Suggests Reduced Cleavage in Pregnancy. Journal of the Endocrine Society, 1(3), 202-210.
Scopus34 WoS24 Europe PMC192017 Torpy, D. J. (2017). GLUCOCORTICOID REPLACEMENT IN CHRONIC ADRENAL INSUFFICIENCY: EVALUATING THE EVIDENCE FOR OPTIMAL THERAPY.. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 23(1), 113-115.
Scopus2 WoS1 Europe PMC12017 De Sousa, S., Chapman, I., Falhammar, H., & Torpy, D. (2017). Dopa-testotoxicosis: disruptive hypersexuality in hypogonadal men with prolactinomas treated with dopamine agonists. Endocrine, 55(2), 618-624.
Scopus42 WoS26 Europe PMC262017 Nenke, M. A., Lewis, J. G., Rankin, W., Shaw, D., & Torpy, D. J. (2017). Corticosteroid-binding globulin cleavage may be pathogen-dependent in bloodstream infection. Clinica Chimica Acta, 464, 176-181.
Scopus7 WoS7 Europe PMC62017 Tirosh, A., Papadakis, G., Chittiboina, P., Lyssikatos, C., Belyavskaya, E., Keil, M., . . . Stratakis, C. (2017). 3D Volumetric Measurements of GH Secreting Adenomas Correlate with Baseline Pituitary Function, Initial Surgery Success Rate, and Disease Control. Hormone and Metabolic Research, 49(06), 440-445.
2016 Gerstein, H. C., Bosch, J., Dagenais, G. R., Díaz, R., Jung, H., Maggioni, A. P., . . . Bustos, B. (2016). Cardiovascular and other outcomes postintervention with insulin glargine and omega-3 fatty acids (ORIGINALE). Diabetes Care, 39(5), 709-716.
Scopus52 WoS45 Europe PMC392016 Falhammar, H., & Torpy, D. J. (2016). A 42-year-old man presented with adrenal incidentaloma due to non-classic congenital adrenal hyperplasia with a novel CYP21A2 mutation. Internal Medicine Journal, 46(9), 1115-1116.
Scopus4 WoS4 Europe PMC32016 Baumann, A., Conway, J., Rosenfeld, H., Le Cong, T., Torpy, D. J., & Rankin, W. (2016). Non-islet cell tumour-induced hypoglycaemia secondary to haemangiopericytoma: A case report.. Pathology, 48 Suppl 1, S89-S90.
2016 Nenke, M. A., Lewis, J. G., Rankin, W., & Torpy, D. J. (2016). Evidence of Reduced CBG Cleavage in Abdominal Obesity: A Potential Factor in Development of the Metabolic Syndrome.. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 48(9), 620.
Europe PMC52016 De Sousa, S. M. C., Kassahn, K. S., McIntyre, L. C., Chong, C. E., Scott, H. S., & Torpy, D. J. (2016). Case report of whole genome sequencing in the XY female: identification of a novel SRY mutation and revision of a misdiagnosis of androgen insensitivity syndrome. BMC Endocrine Disorders, 16(1), 58-1-58-7.
Scopus7 WoS4 Europe PMC42016 Henley, D., Brown, S., Pennell, C., Lye, S., & Torpy, D. (2016). Evidence for central hypercortisolism and elevated blood pressure in adolescent offspring of mothers with pre-eclampsia. Clinical Endocrinology, 85(4), 583-589.
Scopus24 WoS16 Europe PMC152016 Meyer, E., Nenke, M., Rankin, W., Lewis, J., & Torpy, D. (2016). Corticosteroid-binding globulin: a review of basic and clinical advances. Hormone and Metabolic Research, 48(6), 359-371.
Scopus103 WoS76 Europe PMC792016 Nenke, M., Lewis, J., Rankin, W., & Torpy, D. (2016). Evidence of Reduced CBG Cleavage in Abdominal Obesity: A Potential Factor in Development of the Metabolic Syndrome. Hormone and Metabolic Research, 48(8), 523-528.
Scopus7 WoS6 Europe PMC32016 Nenke, M., Lewis, J., Rankin, W., McWilliams, L., Metcalf, R., Proudman, S., & Torpy, D. (2016). Reduced corticosteroid-binding globulin cleavage in active rheumatoid arthritis. Clinical Endocrinology, 85(3), 369-377.
Scopus11 WoS7 Europe PMC72016 Nenke, M., Holmes, M., Rankin, W., Lewis, J., & Torpy, D. (2016). Corticosteroid-binding globulin cleavage is paradoxically reduced in alpha-1 antitrypsin deficiency: implications for cortisol homeostasis. Clinica Chimica Acta, 452, 27-31.
Scopus19 WoS15 Europe PMC162016 Falhammar, H., & Torpy, D. (2016). Congenital adrenal hyperplasia due to 21-hydroxylase deficiency presenting as adrenal incidentaloma: a systematic review and meta-analysis. Endocrine Practice, 22(6), 736-752.
Scopus55 WoS37 Europe PMC342016 Maiden, M., Chapman, M., Torpy, D., Kuchel, T., Clarke, I., Nash, C., . . . Ludbrook, G. (2016). Triiodothyronine administration in a model of septic shock: A randomized blinded placebo-controlled trial. Critical Care Medicine, 44(6), 1153-1160.
Scopus5 WoS5 Europe PMC52016 Bornstein, S., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G., . . . Torpy, D. (2016). Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism, 101(2), 364-389.
Scopus1257 WoS842 Europe PMC8062016 Rushworth, R., Falhammar, H., Munns, C., Maguire, A., & Torpy, D. (2016). Hospital admission patterns in children with CAH: admission rates and adrenal crises decline with age. International Journal of Endocrinology, 2016, 5748264-1-5748264-7.
Scopus21 WoS20 Europe PMC182015 Rushworth, R., & Torpy, D. (2015). Adrenal insufficiency in Australia: Is it possible that the use of lower dose, short-acting glucocorticoids has increased the risk of adrenal crises?. Hormone and Metabolic Research, 47(6), 427-432.
Scopus33 WoS29 Europe PMC262015 Nenke, M., Haylock, C., Rankin, W., Inder, W., Gagliardi, L., Eldridge, C., . . . Torpy, D. (2015). Low-dose hydrocortisone replacement improves wellbeing and pain tolerance in chronic pain patients with opioid-induced hypocortisolemic responses. A pilot randomized, placebo-controlled trial. Psychoneuroendocrinology, 56, 157-167.
Scopus26 WoS22 Europe PMC192015 Rushworth, R., & Torpy, D. (2015). Modern hydrocortisone replacement regimens in adrenal insufficiency patients and the risk of adrenal crisis. Hormone and Metabolic Research, 47(9), 637-642.
Scopus26 WoS23 Europe PMC182015 Louise Rushworth, R., Slobodian, P., & Torpy, D. J. (2015). Interruptions to supply of high-dose hydrocortisone tablets and the incidence of adrenal crises. Clinical Endocrinology, 83(6), 999-1000.
Scopus7 WoS5 Europe PMC22015 Petersen, K. S., Rushworth, R. L., Clifton, P. M., & Torpy, D. J. (2015). Recurrent nocturnal hypoglycaemia as a cause of morning fatigue in treated Addison's disease - favourable response to dietary management: A case report. BMC Endocrine Disorders, 15(1), 5 pages.
Scopus13 WoS8 Europe PMC82015 Marathe, C., Drogemuller, C., Marathe, J., Loudavaris, T., Hawthorne, W., O'Connell, P., . . . Torpy, D. (2015). Islet cell transplantation in Australia: screening, remote transplantation, and incretin hormone secretion in insulin independent patients. Hormone and Metabolic Research, 47(1), 16-23.
Scopus8 WoS8 Europe PMC52015 Dorin, R., Qualls, C., Torpy, D., Schrader, R., & Urban, F. (2015). Reversible increase in maximal cortisol secretion rate in septic shock. Critical Care Medicine, 43(3), 549-556.
Scopus13 WoS11 Europe PMC92015 Nenke, M., Rankin, W., Chapman, M., Stevens, N., Diener, K., Hayball, J., . . . Torpy, D. (2015). Depletion of high affinity corticosteroid-binding globulin corresponds to illness severity in sepsis and septic shock; clinical implications. Clinical Endocrinology, 82(6), 801-807.
Scopus49 WoS42 Europe PMC292015 Torpy, D. J. (2015). Screening for ACTH-dependent hypercortisolism in patients with pituitary incidentaloma. European Journal of Endocrinology, 172(4), C1-C4.
Scopus2 WoS2 Europe PMC22014 Jung, C., Greco, S., Nguyen, H., Ho, J., Lewis, J., Torpy, D., & Inder, W. (2014). Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers. BMC Endocrine Disorders, 14(1), 10 pages.
Scopus93 WoS65 Europe PMC702014 Gagliardi, L., Schreiber, A., Hahn, C., Feng, J., Cranston, T., Boon, H., . . . Scott, H. (2014). ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism, 99(9), E1784-E1792.
Scopus105 WoS69 Europe PMC742014 Gagliardi, L., Nenke, M., Thynne, T., von der Borch, J., Rankin, W., Henley, D., . . . Torpy, D. (2014). Continuous subcutaneous hydrocortisone infusion therapy in Addison's disease: a randomized, placebo-controlled clinical trial. The Journal of Clinical Endocrinology & Metabolism, 99(11), 4149-4157.
Scopus68 WoS48 Europe PMC432014 Nguyen, P., Lewis, J., Sneyd, J., Lee, R., Torpy, D., & Shorten, P. (2014). Development of a formula for estimating plasma free cortisol concentration from a measured total cortisol concentration when elastase-cleaved and intact corticosteroid binding globulin coexist. Journal of Steroid Biochemistry and Molecular Biology, 141, 16-25.
Scopus24 WoS22 Europe PMC152014 Rushworth, R., & Torpy, D. (2014). A descriptive study of adrenal crises in adults with adrenal insufficiency: increased risk with age and in those with bacterial infections. BMC Endocrine Disorders, 14(1), 79-1-79-8.
Scopus53 WoS42 Europe PMC392014 Gagliardi, L., Scott, H., Feng, J., & Torpy, D. (2014). A case of Aromatase deficiency due to a novel CYP19A1 mutation. BMC Endocrine Disorders, 14(1), 1-7.
Scopus37 WoS31 Europe PMC162013 Clifton, V., Hodyl, N., Fogarty, P., Torpy, D., Roberts, R., Nettelbeck, T., . . . Hetzel, B. (2013). The impact of iodine supplementation and bread fortification on urinary iodine concentrations in a mildly iodine deficient population of pregnant women in South Australia. Nutrition Journal, 12(1), 1-5.
Scopus43 WoS33 Europe PMC222013 Lim, W., Torpy, D., & Jeffries, W. (2013). The medical management of Cushing's syndrome during pregnancy. European Journal of Obstetrics Gynecology and Reproductive Biology, 168(1), 1-6.
Scopus54 WoS40 Europe PMC282013 O'Connell, P., Holmes-Walker, D., Goodman, D., Hawthorne, W., Loudovaris, T., Gunton, J., . . . Kay, T. (2013). Multicenter Australian trial of islet transplantation: Improving accessibility and outcomes. American Journal of Transplantation, 2013(13), 1850-1858.
Scopus96 WoS80 Europe PMC662013 Petersen, K., Torpy, D., Chapman, I., Guha, S., Clifton, P., Turner, K., & Keogh, J. (2013). Food label education does not reduce sodium intake in people with type 2 diabetes mellitus. A randomised controlled trial. Appetite, 68(1), 147-151.
Scopus28 WoS28 Europe PMC232012 Torpy, D. (2012). Combination chemotherapy in advanced adrenocortical carcinoma. New England Journal of Medicine, 366(23), 2189-2197.
Scopus692 WoS541 Europe PMC4852012 Gagliardi, L., Ling, K., Kok, C., Carolan, J., Brautigan, P., Kenyon, R., . . . Scott, H. (2012). Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocrine-Related Cancer, 19(3), 19-23.
Scopus6 WoS6 Europe PMC52012 Marathe, C., & Torpy, D. (2012). A role for corticosteroid-binding globulin variants in stress-related disorders. Expert Review of Endocrinology & Metabolism, 7(3), 301-308.
Scopus2 WoS32012 Torpy, D., Lundgren, B., Ho, J., Lewis, J., Scott, H., & Mericq, V. (2012). CBG Santiago: a novel CBG mutation. Journal of Clinical Endocrinology and Metabolism, 97(1), E151-E155.
Scopus25 WoS21 Europe PMC142012 Bosch, J., Gerstein, H. C., Dagenais, G. R., Díaz, R., Dyal, L., Jung, H., . . . Caccavo, A. (2012). N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. New England Journal of Medicine, 367(4), 309-318.
Scopus809 WoS663 Europe PMC5732012 Gerstein, H. C., Bosch, J., Dagenais, G. R., Díaz, R., Jung, H., Maggioni, A. P., . . . Bustamante Labarta, M. (2012). Basal insulin and cardiovascular and other outcomes in dysglycemia. New England Journal of Medicine, 367(4), 319-328.
Scopus1460 WoS1194 Europe PMC9482012 Ting, R. -D., Keech, A. C., Drury, P. L., Donoghoe, M. W., Hedley, J., Jenkins, A. J., . . . Stanton, K. (2012). Benefits and Safety of Long-Term Fenofibrate Therapy in People With Type 2 Diabetes and Renal Impairment The FIELD Study. DIABETES CARE, 35(2), 218-225.
WoS91 Europe PMC752011 Cizza, G., Bernardi, L., Smirne, N., Maletta, R., Tomaino, C., Costanzo, A., . . . Bruni, A. (2011). Clinical manifestations of highly prevalent corticosteroid-binding globulin mutations in a village in Southern Italy. Journal of Clinical Endocrinology and Metabolism, 96(10), E1684-E1693.
Scopus27 WoS22 Europe PMC182011 Simon, S., Torpy, D., Brophy, B., Blumbergs, P., Selva-Nayagam, D., & Crompton, J. (2011). Neuro-ophthalmic manifestations and outcomes of pituitary apoplexy - a life and sight-threatening emergency. New Zealand Medical Journal, 124(1335), 52-59.
Scopus19 WoS8 Europe PMC32011 Jung, C., Ho, J., Torpy, D., Rogers, A., Doogue, M., Lewis, J., . . . Inder, W. (2011). A longitudinal study of plasma and urinary cortisol in pregnancy and postpartum. Journal of Clinical Endocrinology and Metabolism, 96(5), 1533-1540.
Scopus314 WoS238 Europe PMC2112010 Ho, J., Chapman, M., O'Connor, S., Lam, S., Edwards, J., Ludbrook, G., . . . Torpy, D. (2010). Characteristics of plasma NOx levels in severe sepsis: High interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels. Clinical Endocrinology, 73(3), 413-420.
Scopus14 WoS11 Europe PMC112010 Wong, K., Wong, V., Ho, J., Torpy, D., McLean, M., & Cheung, N. (2010). High cortisol levels in hyperglycaemic myocardial infarct patients signify stress hyperglycaemia and predict subsequent normalization of glucose tolerance. Clinical Endocrinology, 72(2), 189-195.
Scopus21 WoS17 Europe PMC162010 Gagliardi, L., Ho, J., & Torpy, D. (2010). Corticosteroid-binding globulin: The clinical significance of altered levels and heritable mutations. Molecular and Cellular Endocrinology, 316(1), 24-34.
Scopus70 WoS62 Europe PMC502010 Gagliardi, L., Chapman, I., O'Loughlin, P., & Torpy, D. (2010). Screening for subclinical Cushing's Syndrome in Type 2 Diabetes Mellitus: Low false-positive rates with nocturnal salivary cortisol. Hormone and Metabolic Research, 42(4), 280-284.
Scopus22 WoS19 Europe PMC152010 Gagliardi, L., & Torpy, D. (2010). Subclinical Cushing's syndrome in adrenal incidentaloma: a common problem or an artefact of current diagnostic testing?. Clinical Endocrinology, 72(2), 277-278.
Scopus7 WoS7 Europe PMC62009 Gagliardi, L., Hotu, C., Casey, G., Braund, W., Ling, K., Dodd, T., . . . Torpy, D. (2009). Familial vasopressin-sensitive ACTH-independent macronodular adrenal hyperplasia (VPs-AIMAH): clinical studies of three kindreads. Clinical Endocrinology, 70(6), 883-891.
Scopus42 WoS35 Europe PMC302009 Pfeffer, M. A., Burdmann, E. A., Chen, C. -Y., Cooper, M. E., de Zeeuw, D., Eckardt, K. -U., . . . Toto, R. (2009). A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease. NEW ENGLAND JOURNAL OF MEDICINE, 361(21), 2019-2032.
WoS1528 Europe PMC12942008 Gerstein, H. C., Yusuf, S., Riddle, M., Ryden, L., Bosch, J., Richardson, L., . . . Falu, R. (2008). Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention). American Heart Journal, 155(1), 26-26.e13.
Scopus152 WoS163 Europe PMC1342008 Dorin, R., Pai, H., Ho, J., Lewis, J., Torpy, D., Urban, F., & Qualls, C. (2008). Validation of a simple method of estimating plasma free cortisol: Role of cortisol binding to albumin. Clinical Biochemistry, 42(1-2), 64-71.
Scopus48 WoS46 Europe PMC302008 Cukier, K., Tewari, N., Kurth, F., Schmid, H., Lai, C., & Torpy, D. (2008). Significant response to pasireotide (SOM230) in the treatment of a patient with persistent, refractory Cushing's disease. Clinical Endocrinology, 71(2), 305-307.
Scopus16 WoS15 Europe PMC112007 Torpy, D., & Ho, J. (2007). Corticosteroid-binding globulin gene polymorphisms: clinical implications and links to idiopathic chronic fatigue disorders. Clinical Endocrinology, 67(2), 161-167.
Scopus35 WoS27 Europe PMC232007 Ho, J., Lewis, J., O'Loughlin, P., Bagley, C., Romero, R., Dekker, G., & Torpy, D. (2007). Reduced maternal corticosteroid-binding globulin and cortisol levels in pre-eclampsia and gamete recipient pregnancies. Clinical Endocrinology, 66(6), 869-877.
Scopus72 WoS65 Europe PMC422007 Torpy, D. (2007). Misleading information for consumers. Medical Journal of Australia, 186(9), 483-484.
Scopus12007 Ho, J. T., Keogh, J. B., Bornstein, S. R., Ehrhart-Bornstein, M., Lewis, J. G., Clifton, P. M., & Torpy, D. J. (2007). Moderate weight loss reduces renin and aldosterone but does not influence basal or stimulated pituitary-adrenal axis function. Hormone and Metabolic Research, 39(9), 694-699.
Scopus53 WoS48 Europe PMC392007 Ho, J., & Torpy, D. J. (2007). Evaluation of adrenocortical function in adults. Australian Prescriber, 30(6), 147-149.
2006 Venkatesh, B., Prins, J., Torpy, D., Chapman, M., Joyce, C., Cooper, D. J., . . . Higgins, A. (2006). Relative adrenal insufficiency in sepsis: match point or deuce?. Critical Care and Resuscitation Journal of the Australasian Academy of Critical Care Medicine, 8(4), 376-380.
Scopus3 Europe PMC22006 Ho, J., Al Musalhi, H., Chapman, M., Quach, T., Thomas, P., Bagley, C., . . . Torpy, D. (2006). Septic shock and sepsis: A comparison of total and free plasma cortisol levels. Journal of Clinical Endocrinology and Metabolism, 91(1), 105-114.
Scopus277 WoS231 Europe PMC1692005 Bachmann, A., Sedgley, T., Jackson, R., Gibson, J., Young, R., & Torpy, D. (2005). Glucocorticoid receptor polymorphisms and post-traumatic stress disorder. PsychoNeuroendocrinology, 30(3), 297-306.
Scopus119 WoS110 Europe PMC862005 Lewis, J., Bagley, C., Elder, P., Bachmann, A., & Torpy, D. (2005). Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulin. Clinica Chimica Acta, 359(1-2), 189-194.
Scopus176 WoS144 Europe PMC1222005 Keech, A. C., Scott, R., Best, J., Forder, P., Taskinen, M. R., Simes, R. J., . . . Morris, S. (2005). Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: Baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]. Cardiovascular Diabetology, 4(1), 9 pages.
Scopus83 WoS47 Europe PMC642005 Ilias, I., Torpy, D. J., Pacak, K., Mullen, N., Wesley, R. A., & Nieman, L. K. (2005). Cushing's syndrome due to ectopic corticotropin secretion: Twenty years' experience at the National Institutes of Health. Journal of Clinical Endocrinology and Metabolism, 90(8), 4955-4962.
Scopus545 WoS448 Europe PMC3872004 Mitchell, E., Torpy, D. J., & Bagley, C. J. (2004). Pregnancy-associated corticosteroid-binding globulin: High resolution separation of glycan isoforms. Hormone and Metabolic Research, 36(6), 357-359.
Scopus27 WoS22 Europe PMC182004 Barter, P., Best, J., Colman, P., d'Emden, M., Davis, T., Drury, P., . . . Alard, F. (2004). The need for a large-scale trial of fibrate therapy in diabetes: The rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481]. Cardiovascular Diabetology, 3(1), 11 pages.
Scopus95 WoS71 Europe PMC572004 Kleinig, T., & Torpy, D. (2004). Milk-Alkali syndrome: broadening the spectrum of causes to allow early recognition. Internal Medicine Journal, 34(6), 366-NIL_2.
Scopus6 WoS7 Europe PMC62004 Torpy, D., Bachmann, A., Gartside, M., Grice, J., Harris, J., Clifton, P., . . . Whitworth, J. (2004). Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene ALA SER224 polymorphism. Endocrine Research, 30(3), 417-429.
Scopus34 WoS30 Europe PMC222003 Joyner, J. M., Hutley, L. J., Bachmann, A. W., Torpy, D. J., & Prins, J. B. (2003). Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiency. American Journal of Physiology Endocrinology and Metabolism, 284(5 47-5), E1049-E1054.
Scopus23 WoS21 Europe PMC132002 Jackson, R. V., Lafferty, A., Torpy, D. J., & Stratakis, C. (2002). New genetic insights in familial hyperaldosteronism. Annals of the New York Academy of Sciences, 970(1), 77-88.
Scopus44 WoS32 Europe PMC222001 Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Crosbie, G. V., Walters, M. M., . . . Jackson, R. V. (2001). The insulin hypoglycemia test: Hypoglycemic criteria and reproducibility. Journal of Neuroendocrinology, 13(6), 524-530.
Scopus22 WoS17 Europe PMC142001 Torpy, D. J., Bachmann, A. W., Grice, J. E., Fitzgerald, S. P., Phillips, P. J., Whitworth, J. A., & Jackson, R. V. (2001). Familial corticosteroid-binding globulin deficiency due to a novel null mutation: Association with fatigue and relative hypotension. Journal of Clinical Endocrinology and Metabolism, 86(8), 3692-3700.
Scopus102 WoS85 Europe PMC622001 Jackson, R. V., Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Walters, M. M., . . . Whitworth, J. A. (2001). Early rise in blood pressure following administration of adrenocorticotropic hormone-[1-24] in humans. Clinical and Experimental Pharmacology and Physiology, 28(9), 773-775.
Scopus7 WoS6 Europe PMC62001 Nye, E. J., Grice, J. E., Hockings, G. I., Strakosch, C. R., Crosbie, G. V., Walters, M. M., . . . Jackson, R. V. (2001). Adrenocorticotropin stimulation tests in patients with hypothalamic-pituitary disease: Low dose, standard high dose and 8-h infusion tests. Clinical Endocrinology, 55(5), 625-633.
Scopus30 WoS25 Europe PMC182001 Eaton, H. J., Phillips, P. J., Hanieh, A., Cooper, J., Bolt, J., & Torpy, D. J. (2001). Rapid onset of pituitary apoplexy after goserelin implant for prostate cancer: Need for heightened awareness. Internal Medicine Journal, 31(5), 313-314.
Scopus19 WoS15 Europe PMC132000 Lafferty, A. R., Torpy, D. J., Stowasser, M., Taymans, S. E., Lin, J. P., Huggard, P., . . . Stratakis, C. A. (2000). A novel genetic locus for low renin hypertension: Familial hyperaldosteronism type II maps to chromosome 7 (7p22). Journal of Medical Genetics, 37(11), 831-835.
Scopus178 WoS136 Europe PMC1132000 Torpy, D. J., Papanicolaou, D. A., Lotsikas, A. J., Wilder, R. L., Chrousos, G. P., & Pillemer, S. R. (2000). Responses of the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis to interleukin-6: A pilot study in fibromyalgia. Arthritis and Rheumatism, 43(4), 872-880.
Scopus210 WoS162 Europe PMC1252000 Torpy, D. J., Stratakis, C. A., & Chrousos, G. P. (2000). Familial hyperaldosteronism. Brazilian Journal of Medical and Biological Research, 33(10), 1149-1155.
Scopus4 WoS3 Europe PMC32000 Nye, E. J., Bornstein, S. R., Grice, J. E., Tauchnitz, R., Hockings, G. I., Strakosch, C. R., . . . Torpy, D. J. (2000). Interactions between the stimulated hypothalamic-pituitary-adrenal axis and leptin in humans. Journal of Neuroendocrinology, 12(2), 141-145.
Scopus25 WoS22 Europe PMC182000 Hope, P., Turnbull, H., Farr, S., Morley, J., Rice, K., Chrousos, G., . . . Wittert, G. (2000). Peripheral administration of CRF and urocortin: effects on food intake and the HPA axis in the marsupial Sminthopsis crassicaudata. Peptides, 21(5), 669-677.
Scopus36 WoS33 Europe PMC251999 Torpy, D. J., Chen, C. C., Mullen, N., Doppman, J. L., Carrasquillo, J. A., Chrousos, G. P., & Nieman, L. K. (1999). Primary localization of an ectopic ACTH-producing bronchial carcinoid tumor by Indium 111pentetreotide scintigraphy - Authors' response [5]. Journal of Clinical Endocrinology and Metabolism, 84(9), 3402-3403.
1999 Torpy, D. J., Chen, C. C., Mullen, N., Doppman, J. L., Carrasquillo, J. A., Chrousos, G. P., & Nieman, L. K. (1999). Lack of utility of 111In-pentetreotide scintigraphy in localizing ectopic ACTH producing tumors: Follow-up of 18 patients. Journal of Clinical Endocrinology and Metabolism, 84(4), 1186-1192.
Scopus76 WoS61 Europe PMC451999 Torpy, D. J., Bornstein, S. R., Taylor, W., Tauchnitz, R., & Gordon, R. D. (1999). Leptin levels are suppressed in primary aldosteronism. Hormone and Metabolic Research, 31(9), 533-536.
Scopus28 WoS27 Europe PMC211999 Torpy, D. J., Webster, E. L., Zachman, E. K., Aguilera, G., & Chrousos, G. P. (1999). Urocortin and inflammation: Confounding effects of hypotension on measures of inflammation. Neuroimmunomodulation, 6(3), 182-186.
Scopus38 WoS35 Europe PMC261999 Böttner, A., Eisenhofer, G., Torpy, D. J., Ehrhart-Bornstein, M., Keiser, H. R., Chrousos, G. P., & Bornstein, S. R. (1999). Preliminary report: Lack of leptin suppression in response to hypersecretion of catecholamines in pheochromocytoma patients. Metabolism Clinical and Experimental, 48(5), 543-545.
Scopus32 WoS28 Europe PMC131999 Nye, E. J., Hockings, G. I., Grice, J. E., Strakosch, C. R., Torpy, D. J., & Jackson, R. V. (1999). The use of naloxone for investigating disorders of the hypothalamic- pituitary-adrenal axis. Endocrinologist, 9(3), 161-182.
Scopus6 WoS61998 Stratakis, C. A., Kirschner, L. S., Taymans, S. E., Tomlinson, I. P. M., Marsh, D. J., Torpy, D. J., . . . Carney, J. A. (1998). Carney complex, Peutz-Jeghers syndrome, Cowden disease, and Bannayan- Zonana syndrome share cutaneous and endocrine manifestations, but not genetic loci. Journal of Clinical Endocrinology and Metabolism, 83(8), 2972-2976.
Scopus60 WoS43 Europe PMC321998 Joyner, J. M., Grice, J. E., Hockings, G. I., Torpy, D. J., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1998). Inhibition of naloxone-stimulated adrenocorticotropin release by alprazolam in myotonic dystrophy patients. Journal of Neuroendocrinology, 10(5), 391-395.
Scopus7 WoS6 Europe PMC41998 Bornstein, S. R., Webster, E. L., Torpy, D. J., Richman, S. J., Mitsiades, N., Igel, M., . . . Chrousos, G. P. (1998). Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation. Endocrinology, 139(4), 1546-1555.
Scopus104 WoS87 Europe PMC631998 Torpy, D. J., Gordon, R. D., Lin, J. P., Huggard, P. R., Taymans, S. E., Stowasser, M., . . . Stratakis, C. A. (1998). Familial Hyperaldosteronism Type II: Description of a Large Kindred and Exclusion of the Aldosterone Synthase (CYP11B2) Gene<sup>1</sup>. The Journal of Clinical Endocrinology & Metabolism, 83(9), 3214-3218.
1998 Torpy, D. J., & Stratakis, C. A. (1998). Linkage Analysis of Familial Hyperaldosteronism Type II—Absence of Linkage to the Gene Encoding the Angiotensin II Receptor Type 1. The Journal of Clinical Endocrinology & Metabolism, 83(3), 1046.
1998 Buyalos, R. P., Jackson, R. V., Grice, G. I., Hockings, G. I., Torpy, D. J., Fox, L. M., . . . Azziz, R. (1998). Androgen response to hypothalamic-pituitary-adrenal stimulation with naloxone in women with myotonic muscular dystrophy. Journal of Clinical Endocrinology and Metabolism, 83(9), 3219-3224.
Scopus6 WoS7 Europe PMC21998 Torpy, D. J., Bornstein, S. R., & Chrousos, G. P. (1998). Leptin and interleukin-6 in sepsis. Hormone and Metabolic Research, 30(12), 726-729.
Scopus111 WoS93 Europe PMC611998 Taymans, S. E., Pack, S., Pak, E., Torpy, D. J., Zhuang, Z., & Stratakis, C. A. (1998). Human CYP11B2 (aldosterone synthase) maps to chromosome 8q24.3. Journal of Clinical Endocrinology and Metabolism, 83(3), 1033-1036.
Scopus90 WoS70 Europe PMC441998 Torpy, D. J., Tsigos, C., Lotsikas, A. J., Defensor, R., Chrousos, G. P., & Papanicolaou, D. A. (1998). Acute and delayed effects of a single-dose injection of interleukin-6 on thyroid function in healthy humans. Metabolism Clinical and Experimental, 47(10), 1289-1293.
Scopus85 WoS65 Europe PMC471998 Bornstein, S. R., Torpy, D. J., Shek, E. W., Brands, M. W., & Hall, J. E. (1998). Leptin and the renin-angiotensin-aldosterone system [1] (multiple letters). Hypertension, 32(2), 376-377.
Scopus13 WoS14 Europe PMC131998 Torpy, D. J., Bornstein, S. R., Cizza, G., & Chrousos, G. P. (1998). The effects of glucocorticoids on leptin levels in humans may be restricted to acute pharmacologic dosing [1]. Journal of Clinical Endocrinology and Metabolism, 83(5), 1821-1822.
Scopus27 WoS24 Europe PMC211998 Torpy, D. J., Stratakis, C. A., & Gordon, R. D. (1998). Linkage analysis of familial hyperaldosteronism type II - Absence of linkage to the gene encoding the angiotensin II receptor type 1 [6]. Journal of Clinical Endocrinology and Metabolism, 83(3), 1046.
Scopus36 WoS30 Europe PMC241998 Chrousos, G. P., Torpy, D. J., & Gold, P. W. (1998). Interactions between the hypothalamic-pituitary-adrenal axis and the female reproductive system: Clinical implications. Annals of Internal Medicine, 129(3), 229-240.
Scopus602 Europe PMC3731998 Torpy, D. J., Gordon, R. D., Lin, J. P., Huggard, P. R., Taymans, S. E., Stowasser, M., . . . Stratakis, C. A. (1998). Familial hyperaldosteronism type II: Description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene. Journal of Clinical Endocrinology and Metabolism, 83(9), 3214-3218.
Scopus93 WoS65 Europe PMC511997 Webster, E. L., Torpy, D. J., Elenkov, I. J., & Chrousos, G. P. (1997). Corticotropin-releasing hormone and inflammation. Review of Clinical Pharmacology and Pharmacokinetics International Edition, 11(1), 32-39. 1997 Nye, E. J., Hockings, G. I., Grice, J. E., Torpy, D. J., Walters, M. M., Crosbie, G. V., . . . Jackson, R. V. (1997). Aspirin inhibits vasopressin-induced hypothalamic-pituitary-adrenal activity in normal humans. Journal of Clinical Endocrinology and Metabolism, 82(3), 812-817.
Scopus40 WoS36 Europe PMC301997 Torpy, D. J., Papanicolaou, D. A., & Chrousos, G. P. (1997). Sexual dimorphism of the human stress response may be due to estradiol- mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis [1]. Journal of Clinical Endocrinology and Metabolism, 82(3), 982.
Scopus21 WoS16 Europe PMC101997 Torpy, D. J., Stratakis, C. A., & Chrousos, G. P. (1997). Hyper- and Hypoaldosteronism. Vitamins and Hormones, 57(C), 177-216.
Scopus39 WoS21 Europe PMC111997 Torpy, D. J., & Chrousos, G. P. (1997). Stress and critical illness: The integrated immune/hypothalamic- pituitary-adrenal axis response. Journal of Intensive Care Medicine, 12(5), 225-238.
Scopus81997 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1997). Diurnal effects of fluoxetine and naloxone on the human hypothalamic- pituitary-adrenal axis. Clinical and Experimental Pharmacology and Physiology, 24(6), 421-423.
Scopus8 WoS5 Europe PMC31997 Bornstein, S. R., Torpy, D. J., Chrousos, G. P., Licinio, J., & Engelmann, L. (1997). Leptin levels are elevated despite low thyroid hormone levels in the 'euthyroid sick' syndrome [9]. Journal of Clinical Endocrinology and Metabolism, 82(12), 4278-4279.
Scopus21 Europe PMC101997 Torpy, D. J., Papanicolaou, D. A., & Chrousos, G. P. (1997). Sexual Dimorphism of the Human Stress Response May Be Due to Estradiol-Mediated Stimulation of Hypothalamic Corticotropin-Releasing Hormone Synthesis1. The Journal of Clinical Endocrinology & Metabolism, 82(3), 982.
1997 Nye, E. J., Hockings, G. I., Grice, J. E., Torpy, D. J., Walters, M. M., Crosbie, G. V., . . . Jackson, R. V. (1997). Aspirin Inhibits Vasopressin-Induced Hypothalamic-Pituitary-Adrenal Activity in Normal Humans1. The Journal of Clinical Endocrinology & Metabolism, 82(3), 812-817.
1997 Bornstein, S. R., Torpy, D. J., Chrousos, G. P., Licinio, J., & Engelmann, L. (1997). Leptin levels are elevated despite low thyroid hormone levels in the "euthyroid sick" syndrome. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 82(12), 4278-4279.
WoS131996 Webster, E. L., Lewis, D. B., Torpy, D. J., Zachman, E. K., Rice, K. C., & Chrousos, G. P. (1996). In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral inflammation. Endocrinology, 137(12), 5747-5750.
Scopus291 WoS275 Europe PMC1991996 Papanicolaou, O. A., Tsigos, C., Torpy, D., Defensor, R., Thompson, B., & Chrousos, O. P. (1996). Recombinant interleukin-6 effects on pituitary secretion in humans. Journal of Investigative Medicine, 44(3), 266.
Scopus81996 Torpy, D. J., & Chrousos, G. P. (1996). The three-way interactions between the hypothalamic-pituitary-adrenal and gonadal axes and the immune system. Bailliere S Clinical Rheumatology, 10(2), 181-198.
Scopus70 WoS52 Europe PMC341995 Torpy, D. J., Grice, J. E., Hockings, G. I., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1995). EFFECT OF SODIUM VALPROATE ON NALOXONE‐STIMULATED ACTH AND CORTISOL RELEASE IN HUMANS. Clinical and Experimental Pharmacology and Physiology, 22(6-7), 441-443.
Scopus12 WoS13 Europe PMC21995 Torpy, D. J., Grice, J. E., Hockings, G. I., Crosbie, G. V., Walters, M. M., & Jackson, R. V. (1995). The effect of desipramine on basal and naloxone-stimulated cortisol secretion in humans: Interaction of two drugs acting on noradrenergic control of adrenocorticotropin secretion. Journal of Clinical Endocrinology and Metabolism, 80(3), 802-806.
Scopus15 WoS13 Europe PMC81995 Grice, J. E., Jackson, R. V., Hockings, G. I., Torpy, D. J., Walters, M. M., & Crosbie, G. V. (1995). Adrenocorticotropin hyperresponse to the corticotropin-releasing hormone-mediated stimulus of naloxone in patients with myotonic dystrophy. Journal of Clinical Endocrinology and Metabolism, 80(1), 179-184.
Scopus17 WoS17 Europe PMC81995 Jackson, R. V., Grice, J. E., Hockings, G. I., & Torpy, D. J. (1995). Naloxone-induced ACTH release: Mechanism of action in humans. Clinical Endocrinology, 43(4), 423-424.
Scopus18 WoS16 Europe PMC121995 Hlockings, G. I., Grice, J. E., Watters, M. M., Crosbie, G. V., Torpy, D. J., & Jackson, R. V. (1995). A synergistic adrenocorticotropin response to naloxone and vasopressin in normal humans: Evidence that naloxone stimulates endogenous corticotropin-releasing hormone. Neuroendocrinology, 61(2), 198-206.
Scopus21 WoS22 Europe PMC91994 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1994). Alprazolam attenuates vasopressin-stimulated adrenocorticotropin and cortisol release: Evidence for synergy between vasopressin and corticotropin-releasing hormone in humans. Journal of Clinical Endocrinology and Metabolism, 79(1), 140-144.
Scopus45 WoS41 Europe PMC281994 Torpy, D. J., Jackson, R. V., Grice, J. E., Hockings, G. I., Crosbie, G. V., & Walters, M. M. (1994). EFFECT OF FLUMAZENIL ON BASAL AND NALOXONE‐STIMULATED ACTH AND CORTISOL RELEASE IN HUMANS. Clinical and Experimental Pharmacology and Physiology, 21(2), 157-161.
Scopus2 WoS11994 Hockings, G. I., Jackson, R. V., Grice, J. E., Crosbie, G. V., Walters, M. M., Torpy, D. J., & Jackson, A. J. (1994). Paradoxical inhibition by aspirin of naloxone-induced adrenocorticotropin secretion in myotonic dystrophy. Journal of Clinical Endocrinology and Metabolism, 78(6), 1424-1427.
Scopus6 WoS6 Europe PMC41993 Torpy, D. J., Grice, J. E., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1993). Alprazolam blocks the naloxone-stimulated hypothalamo-pituitary-adrenal axis in man. Journal of Clinical Endocrinology and Metabolism, 76(2), 388-391.
Scopus63 WoS63 Europe PMC361993 Torpy, D. J., Jackson, R. V., Grice, J. E., Hockings, G. I., Strakosch, C. R., & Topliss, D. J. (1993). NALOXONE STIMULATION OF ACTH SECRETION DURING PETROSAL SINUS SAMPLING IN CUSHING'S SYNDROME. Clinical and Experimental Pharmacology and Physiology, 20(5), 299-302.
Scopus10 WoS11 Europe PMC4- Coates, P., Penko, D., Nitschke, J., Johnson, J., Kireta, S., Concannon, E., . . . Drogemuller, C. (n.d.). The Proof of Concept INCEPTR trial 12 month outcomes - Intracutaneous islet transplant in humans into pre-vascularised Novosorb® neodermis. Endocrine Abstracts.
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Book Chapters
Year Citation 2022 Torpy, D. J., O’Reilly, M. W., & De Sousa, S. M. C. (2022). Adrenal Disease in Pregnancy. In J. A. H. Wass, W. Arlt, & R. K. Semple (Eds.), Oxford Textbook of Endocrinology and Diabetes 3e (pp. 1479-1488). Oxford University PressOxford.
DOI2012 Marathe, C., & Torpy, D. (2012). Corticosteroid-Binding Globulin Gene Mutations and Chronic Fatigue/Pain Syndromes: An Overview of Current Evidence. In C. R. Snell (Ed.), An International Perspective on the Future of Research in Chronic Fatigue Syndrome. 2011 Torpy, D. (2011). A woman with palpitations.. In P. Devitt, J. Mitchell, & C. Hamilton Craig (Eds.), Clinical Problems in Medicine and Surgery E-Book (3rd ed., pp. 336-342). Elsevier Health Sciences. 2003 Stergiopoulos, S. G., Torpy, D. J., & Stratakis, C. A. (2003). Primary aldosteronism: Pathophysiology, diagnosis and management. In Endocrine Surgery (pp. 401-410). 2001 Torpy, D., & Jackson, R. V. (2001). Adrenocorticotropin - physiology and clinical aspects.. In K. L. Becker (Ed.), Principles and Practice of Endocrinology and Metabolism (3rd ed., pp. 153-159). Lippincott Williams & Wilkins. 1999 Ratnaike, R. N., Buttery, J. E., & Torpy, D. (1999). Endocrine, metabolic and miscellaneous causes of diarrhoea.. In R. N. Ratnaike (Ed.), Diarrhoea and Constipation in Geriatric Practice (pp. 171-184). Cambridge University Press. 1997 Torpy, D., & Chrousos, G. P. (1997). The general adaptation syndrome: an overview.. In K. P. Ober (Ed.), Endocrinology of Critical Disease (pp. 1-24). Humana Press. -
Conference Papers
Year Citation 2023 Wu, D., Rushworth, L., Torpy, D. J., & Coates, P. T. H. (2023). Chronic Pancreatitis in children under 18 in New South Wales, Australia: establishing suitable candidates for total pancreatectomy and islet auto transplantation (TPIAT). In TRANSPLANTATION Vol. 107 (pp. 189). CA, San Diego: LIPPINCOTT WILLIAMS & WILKINS.
DOI2018 De Sousa, S. M. C., McCormack, A. I., McGrath, S., & Torpy, D. J. (2018). Use of prolactin in inferior petrosal sinus sampling is misleading. In CLINICAL ENDOCRINOLOGY Vol. 89 (pp. 32). Perth, AUSTRALIA: WILEY.
WoS12016 Nenke, M. A., Holmes, M., Rankin, W., Lewis, J. G., & Torpy, D. J. (2016). Paradoxical reduction in corticosteroid-binding globulin cleavage is seen in alpha-1 antitrypsin deficiency: implications for cortisol homeostasis. In CLINICAL ENDOCRINOLOGY Vol. 84 (pp. 41). Adelaide, AUSTRALIA: WILEY. 2016 Hodyl, N. A., Stark, M. J., Nenke, M. A., Lewis, J. G., & Torpy, D. J. (2016). Displacement of Cortisol from Corticosteroid-Binding Globulin by High Fetal Progesterone May Drive Free Fetal Cortisol.. In REPRODUCTIVE SCIENCES Vol. 23 (pp. 310A). Montreal, CANADA: SAGE PUBLICATIONS INC. 2016 Hue, S. M., Torpy, D. J., Bennett, G., Kay, T. W., Thomas, H. E., Goodman, D., . . . Coates, P. T. (2016). De-novo donor-specific anti-HLA antibodies in islet cell transplant recipients in Australia. In TRANSPLANTATION Vol. 100 (pp. S405). LIPPINCOTT WILLIAMS & WILKINS. 2015 O'Connell, P., Holmes-Walker, D. J., Goodman, D., Hawthorne, W. J., Loudovaris, T., Gunton, J. E., . . . Kay, T. W. (2015). Five years outcomes from the Australian multicentre trial of islet transplantation. In XENOTRANSPLANTATION Vol. 22 (pp. S10-S11). Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2015 Drogemuller, C., Radford, T. M., Torpy, D. J., Rainis, H. A., Barton, F. B., & Coates, P. T. (2015). Effects of etanercept route of administration in clinical allogeneic islet transplantation: an analysis from the collaborative islet transplant registry (CITR). In XENOTRANSPLANTATION Vol. 22 (pp. S187-S188). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
WoS22015 O'Connell, P. J., Holmes-Walker, D. J., Goodman, D., Hawthorne, W. J., Loudovaris, T., Gunton, J. E., . . . Kay, T. W. (2015). FIVE YEARS OUTCOMES FROM THE AUSTRALIAN MULTICENTRE TRIAL OF ISLET TRANSPLANTATION.. In TRANSPLANTATION Vol. 99 (pp. S17). Melbourne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS. 2015 Drogemuller, C., Radford, T. M., Torpy, D. J., Rainis, H. A., Barton, F. B., & Coates, P. T. (2015). EFFECTS OF ETANERCEPT ROUTE OF ADMINISTRATION IN CLINICAL ALLOGENEIC ISLET TRANSPLANTATION: AN ANALYSIS FROM THE COLLABORATIVE ISLET TRANSPLANT REGISTRY (CITR).. In TRANSPLANTATION Vol. 99 (pp. S313). Melbourne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS. 2010 Ho, J. T., O'Connor, S., Chapman, M. J., Edwards, J., Lam, S., Ludbrook, G., . . . Torpy, D. J. (2010). Plasma NOx Is Not a Suitable Tissue Marker To Guide Glucocorticoid Therapy in Severe Sepsis.. In ENDOCRINE REVIEWS Vol. 31 (pp. 1 page). San Diego, CA: ENDOCRINE SOC. 2010 Jung, C., Ho, J. T., Torpy, D. J., Lewis, J. G., & Inder, W. J. (2010). A Longitudinal Study of Plasma and Urinary Cortisol in Pregnancy and the Post-Partum Period.. In ENDOCRINE REVIEWS Vol. 31 (pp. 1 page). San Diego, CA: ENDOCRINE SOC. 2007 Torpy, D. J., & Ho, J. T. (2007). Value of free cortisol measurement in systemic infection. In Hormone and Metabolic Research Vol. 39 (pp. 439-444). Bethesda, MD: GEORG THIEME VERLAG KG.
DOI Scopus35 WoS30 Europe PMC232002 Torpy, D. J., Mullen, N., Ilias, I., & Nieman, L. K. (2002). Association of hypertension and hypokalemia with Cushing's syndrome caused by ectopic ACTH secretion: A series of 58 cases. In K. Pacak, & G. Eisenhofer (Eds.), Annals of the New York Academy of Sciences Vol. 970 (pp. 134-144). BETHESDA, MARYLAND: NEW YORK ACAD SCIENCES.
DOI Scopus150 WoS108 Europe PMC901999 Elenkov, I. J., Webster, E. L., Torpy, D. J., & Chrousos, G. P. (1999). Stress, corticotropin-releasing hormone, glucocorticoids, and the immune/inflammatory response: Acute and chronic effects. In M. Cutolo, A. T. Masi, J. W. J. Bijlsma, I. C. Chikanza, H. L. Bradlow, & L. Castagnetta (Eds.), Annals of the New York Academy of Sciences Vol. 876 (pp. 1-13). GENOA, ITALY: NEW YORK ACAD SCIENCES.
DOI Scopus213 WoS170 Europe PMC1191999 Lafferty, A. R., Torpy, D. J., Huggard, P., Gordon, R. D., & Stratakis, C. A. (1999). Familial hyperaldosteronism type II: Identification of potential disease loci using linkage analysis. In PEDIATRIC RESEARCH Vol. 45 (pp. 92A). INT PEDIATRIC RESEARCH FOUNDATION, INC. 1998 Grice, J. E., Torpy, D. J., Hockings, G. I., Walters, M. M., Crosbie, G. V., & Jackson, R. V. (1998). Pituitary-adrenal responses to combined oral D-fenfluramine and intravenous naloxone in humans. In Clinical and Experimental Pharmacology and Physiology Vol. 25 (pp. 621-623). FREMANTLE, AUSTRALIA: BLACKWELL SCIENCE.
DOI Scopus2 WoS2 Europe PMC21998 Webster, E. L., Torpy, D. J., Elenkov, I. J., & Chrousos, G. P. (1998). Corticotropin-releasing hormone and inflammation. In S. M. McCann, J. M. Lipton, E. M. Sternberg, G. P. Chrousos, P. W. Gold, & C. C. Smith (Eds.), Annals of the New York Academy of Sciences Vol. 840 (pp. 21-32). BETHESDA, MARYLAND: NEW YORK ACAD SCIENCES.
DOI Scopus156 WoS137 Europe PMC841996 Jackson, R. V., Hockings, G. I., Torpy, D. J., Grice, J. E., Crosbie, G. V., Walters, M. M., & Strakosch, C. R. (1996). New diagnostic tests for Cushing's syndrome: Uses of naloxone, vasopressin and alprazolam. In Clinical and Experimental Pharmacology and Physiology Vol. 23 (pp. 579-581). Australia: WILEY.
DOI Scopus5 WoS5 Europe PMC21990 BANNISTER, K. M., GAFFNEY, R., & TORPY, D. J. (1990). REDUCING THE FALSE NEGATIVE RATE OF RADIONUCLIDE SCANS IN RENAL-ARTERY STENOSIS (RAS) - THE VALUE OF CAPTOPRIL. In KIDNEY INTERNATIONAL Vol. 38 (pp. 544). BLACKWELL SCIENCE INC. -
Conference Items
Year Citation 2023 Wu, D., Zuiani, J., Drogemuller, C., De Sousa, S., Adelson, D., Torpy, D. J., & Coates, P. T. H. (2023). The Epidemiology of Hereditary Pancreatitis in Australia and its effect on patient of Total Pancreatectomy with Islet Auto-Transplantation (TPIAT). Poster session presented at the meeting of Abstracts of the IPITA-IXA-CTRMS Joint Congress 2023, as published in Transplantation. San Diego, CA, USA: Lippincott Williams & Wilkins.
DOI2019 Baranoff, J., Saranapala, M., Burke, A. L., Collins, K., & Torpy, D. (2019). Acceptability, credibility, and effectiveness of group-based cognitive behavioral stress management (CBSM) during diet-induced weight loss. Poster session presented at the meeting of 'Applying New Solutions in Health Psychology’ 2019 APS College of Health Psychologists Conference. Stamford Grand Hotel, Glenelg, South Australia. 2017 De Sousa, S. M. C., Chapman, I. M., Falhammar, H., & Torpy, D. J. (2017). Dopa-testotoxicosis: a novel drug toxicity of dopamine agonists in male prolactinoma patients. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2017 De Sousa, S. M. C., Stowasser, M., Feng, J., Schreiber, A. W., Hahn, C. N., Torpy, D. J., . . . Scott, H. S. (2017). Sequence variants in <i>ARMC5</i> are not implicated in familial hyperaldosteronism type II. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2017 Meyer, E. J., De Sousa, S. M. C., Burt, M. G., & Torpy, D. J. (2017). Cavernous internal carotid artery ansurysm: a rare cause of marked hyperprolactinaemia. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL. 2014 Gagliardi, L., Nenke, M. A., Thynne, T. R. J., von der Borch, J., Rankin, W. A., Henley, D. E., . . . Torpy, D. J. (2014). Continuous Subcutaneous Hydrocortisone Infusion Therapy in Addison's Disease; Effects on Health Status in a Randomised Placebo-Controlled Clinical Trial. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC. 2014 Gagliardi, L., Nenke, M. A., Thynne, T. R. J., von der Borch, J., Rankin, W. A., Henley, D. E., . . . Torpy, D. J. (2014). Continuous Subcutaneous Hydrocortisone Infusion Therapy in Addison's Disease; Effects on Health Status in a Randomised Placebo Controlled Clinical Trial. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC. 2012 Marathe, C., Irish, G., & Torpy, D. (2012). The clinical outcome of pituitary adenomas in the cavernous sinus. Poster session presented at the meeting of Endocrine. Florence, Italy. -
Report for External Bodies
Year Citation 2008 Bassett, D., Edwards-Smith, C., Goldney, R., Beltrame, J. F., Riessen, R., Torpy, D., . . . Wilson, D. (2008). The Management of Cardiometabolic Effects in Patients Receiving Antipsychotic Medications.
Grants
| 2011 | ACTH-independent macronodular adrenal hyperplasia. | Royal Adelaide Hospital Research Grant. | Gagliardi L, Scott H, Torpy DJ, Hahn C. | $25,000 |
| 2012 | A randomized placebo controlled crossover pilot study of cortisol replacement in chronic pain patients. | Royal Adelaide Hospital Clinical Research Grant. | Torpy DJ, Rolan P. | $30,000 |
| 2013 | Effect of depletion of cleaved CBG on inflammation in preeclampsia, rheumatoid arthritis and sepsis. | Royal Adelaide Hospital Research Grant. | Nenke M, Lewis J, Torpy DJ. | $50,000 |
| 2015 | Obesity, Stress and the Metebolic Syndrome: Effect of cognitive behavior stress management (CBSM) on the extent and durability of diet-induced weight loss. Role of the biological stress system. | Flinders Medical Centre (FMC) Foundation. Seeding Grant. | Licinio J, Torpy DJ. | $15,000 |
| 2015 | Effect of plasma corticosteroid binding globulin on noradrenaline weaning in septic shock. | RAH Research Grant. | $40,000 | |
| 2016 | High-affinity corticosteroid binding globulin depletion in septic shock: clinical implications | NHMRC Near Miss grant. RAH Special purposes fund. | $40,000 | |
| 2019 | Adrenal cell transplantation for Addison’s disease using biodegradable temporizing matrix technology. | RRC Clinical Project Grant. | Torpy, DJ | $48,000 |
| 2020 | Development of new approaches to measure proteolysis and glycosylation profiling of high and low affinity corticosteroid-binding globulin (CBG) in septic shock using mass spectrometry. | RRC Clinical Project Grant. | $47,840 | |
| 2020 | Purification of CBG for glycosylation analysis in sepsis and distribution studies | Near Miss Funding | $50,000/FHMS $30,511/SAHMRI $19,489 |
Teaching
In addition to the teaching activities below, Prof. Torpy has supervised 11 HDR students to completion from 2001-2021 and currently supervises 5 HDR students.
Undergraduate:
| 1988 – 1991 | Bedside teaching and small group tutorials to undergraduate medical students at the Universities of Adelaide and Queensland in my capacities as Senior Medical Registrar. |
| 1992 – 1995 | Clinical Instructor in Medicine |
| 1998 | Clinical Senior Lecturer in Medicine |
| 1997 – 1998 | Teaching in the field of clinical endocrinology at the National Institutes of Health, USA. Supervision of junior scientific staff in specific laboratory procedures at the NIH. |
| 1997 - 1998 | Lecturer in Endocrinology – MBBS Course Year 2. Includes provision of web-based learning materials. |
| 2000 – 2001 | Supervision of foreign elective students in endocrinology – clinical and research, through postgraduate Medical Education Association of Queensland. |
| 2000 - 2001 |
Problem Based Learning Tutor, Graduate Medical Course, University of Queensland. Provision of case wraps / end core based learning in endocrine related cases University of Adelaide Year 4 students. |
| 2002- | Group based tutorials University of Adelaide Year 4 students diabetes topics. |
Postgraduate:
| 1998 - 1999 | Responsibilities for coordinating an internal medicine training program for basic physician trainees. |
| 2000 – 2001 | Co-supervision of RACP advanced trainees in endocrinology (core year). |
| 2002 – 2012 | Provision of endocrinology tutorials for basic physician trainees. |
| 2002 – 2012 | Supervision of RACP advanced trainees in endocrinology (required year). |
| 2002 - 2012 | Participation in postgraduate teaching of advanced trainees, weekly long cases, and trial exam program. |
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2025 Co-Supervisor Novel applications of molecular imaging and theranostics in endocrine neoplasia. Doctor of Philosophy Doctorate Part Time Mr James Michael McNeil 2025 Co-Supervisor Harnessing a native corticosteroid-binding globulin to treat chronic inflammation and life-threatening septic shock Doctor of Philosophy Doctorate Full Time Mr Declan Emmett Kilgariff 2023 Co-Supervisor Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock Master of Clinical Science Master Part Time Mr Benjamin James Young -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 - 2024 Co-Supervisor Understanding the Relationship of Incretin Hormones, Gastric Emptying and the Glucoregulatory Responses to Nutrients Doctor of Philosophy Doctorate Full Time Dr Ryan Joseph Jalleh 2019 - 2025 Principal Supervisor Exploring Adrenocortical Cell Transplantation for Primary Adrenal Insufficiency Doctor of Philosophy Doctorate Full Time Dr Brigette Marie Clarke 2017 - 2022 Principal Supervisor Corticosteroid-Binding Globulin in Inflammation and Septic Shock Doctor of Philosophy Doctorate Full Time Dr Emily Jane Meyer 2016 - 2020 Principal Supervisor Clinical and Genetic Aspects of Prolactin Hypersecretion Doctor of Philosophy Doctorate Full Time APrf Sunita Maria Christina De Sousa 2015 - 2017 Co-Supervisor The Effect of Dairy 0n Insulin Sensitivity Master of Philosophy (Medical Science) Master Full Time Jordan Linley Peters 2014 - 2017 Principal Supervisor Corticosteroid-Binding Globulin – a Targeted Delivery System for Cortisol. Physiology and Responses to Acute and Chronic Inflammation Doctor of Philosophy Doctorate Full Time Dr Marni Anne Nenke 2010 - 2013 Co-Supervisor Neuro-endocrine Function in Older Men with Chronic Pain - Effects of Chronic Opioid Usage Master of Medical Science Master Part Time Ms Clare Haylock 2010 - 2015 Co-Supervisor Tri-iodothyronine (T3) Therapy in a Pre-Clinical Model of Septic Shock Doctor of Philosophy Doctorate Full Time Dr Matthew Jerome Maiden 2008 - 2011 Principal Supervisor Regulation of Cortisol Secretion in Humans; Relation to Vasopressin Action at the Adrenals in Macronodular and Micronodular Adrenocortical Tumours and Well-Being in Addison's Disease Doctor of Philosophy Doctorate Full Time Dr Lucia Gagliardi 2004 - 2007 Principal Supervisor Nutrition and Vascular Function Doctor of Philosophy Doctorate Full Time Jennifer Beatrice Keogh 2004 - 2007 Principal Supervisor Corticosteroid Binding Globulin: High Resolution Separation of Glycan Isoforms from Plasma of Pregnant Women and Women taking the Combined Oral Contraceptive Pill Master of Medical Science Master Full Time Miss Elizabeth Mitchell 2004 - 2007 Principal Supervisor Cortisol and Blood Pressure Perturbation in the Pathophysiology of Septicaemia, Complicated Pregnancy and Weight Loss/Obesity Doctor of Philosophy Doctorate Full Time Dr Jui Ho -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2011 - 2014 Co-Supervisor The effects of dietary salt restriction and potassium augmentation on diabetes mellitus and hypertension University of South Australia Doctor of Philosophy Doctorate Full Time Kristina Petersen
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Committee Memberships
Date Role Committee Institution Country 2010 - 2012 Chair Organising Committee Annual Endocrine Clinical Education Weekend Update (SA). Australia 2009 - 2012 Member Program Organising Committee Endocrine Society of Australia Annual Scientific Meeting Australia -
Memberships
Date Role Membership Country 2003 - ongoing Member Hanson Institute of Medical Research Australia 1994 - ongoing Member The Endocrine Society (US) United States 1991 - ongoing Member Fellow of the Royal Australasian College of Physicians Australia 1990 - ongoing Member Endocrine Society of Australia Australia 1984 - ongoing Member Australian Medical Association Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2016 - ongoing Board Member Journal of the Endocrine Society Oxford University Press United Kingdom 2011 - 2016 Associate Editor Journal of Clinical Endocrinology and Metabolism Oxford University Press United Kingdom 2010 - 2014 Board Member Hormone and Metabolic Research Thieme India -
Review, Assessment, Editorial and Advice
Date Title Type Institution Country 2012 - 2012 Cancer Grant Reviewer Grant Assessment Pfizer Australia 2009 - 2012 Abstract reviewer Conference Review Endocrine Society of Australia Annual Scientific Meeting Australia 2001 - ongoing Grant reviewer Grant Assessment National Heart Foundation Australia 2000 - 2000 Grant reviewer Grant Assessment Canterbury Medical Research Foundation, University of Otago New Zealand 1999 - 1999 Grant reviewer Grant Assessment The Royal Adelaide Hospital Project Grant Committee Australia 1998 - 2018 Abstract reviewer Conference Review The Endocrine Society (US) Annual Scientific Meeting United States 1997 - ongoing Grant reviewer Grant Assessment National Health and Medical Research Council Australia
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