Eugene Roscioli

Research Interests

Biochemistry & Molecular Biology Biochemistry and Cell Biology Biological Sciences Biotechnology Cell Biology Cell Development, Proliferation and Death Cell Physiology Entrepreneurship Genetics Physiology Cardiac, Respiratory and Vascular Health

Dr Eugene Roscioli

School of Medicine

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Principle investigator, Central Adelaide Local Health Network, RAH, Dept. Thoracic MedicineSenior Adjunct Lecturer (Level C), University of AdelaidePhD, Bachelor of Biotechnology (Hons), Grad Cert. Science and Technology CommerceEugene.Roscioli@adelaide.edu.auEugene.Roscioli@sa.gov.au

Date Position Institution name
2022 - ongoing Florey Research Fellow Royal Adelaide Hospital
2019 - 2021 Mary-Overton Research Fellow Royal Adelaide Hospital
2018 - ongoing Adelaide Medical School Research Committee Member University of Adelaide
2018 - 2022 Chair Adelaide Medical School Early-Mid Career Research Committee University of Adelaide
2018 - ongoing Senior Adjunct Lecturer University of Adelaide
2018 - 2018 Research fellow Royal Adelaide Hospital
2016 - 2017 AstraZeneca Research Fellow Royal Adelaide Hospital
2015 - 2018 Adjunct Lecturer University of Adelaide, Adelaide
2014 - 2015 Research fellow Royal Adelaide Hospital

Date Institution name Country Title
University of Adelaide, Adelaide Australia PhD
University of Adelaide, Adelaide Australia Graduate Certificate
Flinders University, Adelaide Australia Bachelor of Biotechnology
Flinders University, Adelaide Australia Honours (Biotechnology)

Date Title Institution Country
2014 Postdoctoral Research Fellow Royal Adelaide Hospital, Adelaide Australia

Year Citation
2024 Gunn, N. J., Kidd, S. P., Solomon, L. B., Yang, D., Roscioli, E., & Atkins, G. J. (2024). Staphylococcus aureus persistence in osteocytes: weathering the storm of antibiotics and autophagy/xenophagy. Frontiers in Cellular and Infection Microbiology, 14, 1403289-1-1403289-13.
DOI Scopus5 WoS5 Europe PMC2
2023 Asare, P. F., Hurtado, P. R., Tran, H. B., Perkins, G. B., Roscioli, E., & Hodge, S. (2023). Reduction in Rubicon by cigarette smoke is associated with impaired phagocytosis and occurs through lysosomal degradation pathway. Clinical and Experimental Medicine, 23(7), 4041-4055.
DOI Scopus4 WoS4 Europe PMC4
2023 Hodge, G., Jersmann, H., Holmes, M., Asare, P., Roscioli, E., Reynolds, P. N., & Hodge, S. (2023). BLTR1 Is Decreased in Steroid Resistant Pro-Inflammatory CD28nullCD8+ T Lymphocytes in Patients with COPD—The Spillover Hypothesis Explained?. Biology, 12(9), 1261-1-1261-13.
DOI Europe PMC1
2022 Delhove, J., Alawami, M., Macowan, M., Lester, S. E., Nguyen, P. T., Jersmann, H. P. A., . . . Roscioli, E. (2022). Organotypic sinonasal airway culture systems are predictive of the mucociliary phenotype produced by bronchial airway epithelial cells. Scientific Reports, 12(1), 19225-1-19225-11.
DOI Scopus1 WoS1 Europe PMC2
2021 Asare, P. F., Tran, H. B., Hurtado, P. R., Perkins, G. B., Nguyen, P., Jersmann, H., . . . Hodge, S. (2021). Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke. Therapeutic Advances in Respiratory Disease, 15, 17534666211039769-1-17534666211039769-15.
DOI Scopus21 WoS19 Europe PMC18
2021 Gunn, N. J., Zelmer, A. R., Kidd, S. P., Solomon, L. B., Roscioli, E., Yang, D., & Atkins, G. J. (2021). A Human Osteocyte Cell Line Model for Studying Staphylococcus aureus Persistence in Osteomyelitis. Frontiers in Cellular and Infection Microbiology, 11, 781022-1-781022-10.
DOI Scopus14 WoS13 Europe PMC16
2020 Kicic, A., de Jong, E., Ling, K. M., Nichol, K., Anderson, D., Wark, P. A. B., . . . Veerati, P. C. (2020). Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium. Journal of Allergy and Clinical Immunology, 154(6), 1562-1573.
DOI Scopus47 WoS45 Europe PMC42
2020 Poh, W. P., Kicic, A., Lester, S. E., Nguyen, P. T., Bakaletz, L. O., Reynolds, P. N., . . . Roscioli, E. (2020). COPD-related modification to the airway epithelium permits intracellular residence of nontypeable haemophilus influenzae and may be potentiated by macrolide arrest of autophagy. International Journal of COPD, 15, 1253-1260.
DOI Scopus7 WoS7 Europe PMC7
2020 Asari, P., Roscioli, E., Hurtado, P., Tran, H., Mah, C., & Hodge, S. (2020). LC3-associated phagocytosis (LAP): a potentially influential mediator of efferocytosis-related tumour progression and aggressiveness.. Frontiers in Oncology-Molecular and Cellular Oncology, 10, 1298-1-1298-14.
DOI Scopus42 WoS37 Europe PMC36
2019 Poh, M., Kicic, A., Lester, S., Nguyen, P., Bakaletz, L., Reynolds, P., . . . Roscioli, E. (2019). Modification of the airway epithelium during COPD and exposure to macrolides potentiate intracellular infection by Nontypeable Haemophilus influenzae (NTHi) by inhibiting xenophagy.. European Respiratory Journal.
2019 Murphy, J., Ramezanpour, M., Drilling, A., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2019). In vitro characteristics of an airway barrier-disrupting factor secreted by Staphylococcus aureus. International Forum of Allergy and Rhinology, 9(2), 187-196.
DOI Scopus14 WoS13 Europe PMC11
2018 Roscioli, E., Hamon, R., Lester, S., Jersmann, H., Reynolds, P., & Hodge, S. (2018). Airway epithelial cells exposed to wildfire smoke extract exhibit dysregulated autophagy and barrier dysfunction consistent with COPD. Respiratory Research, 19(1), 234-1-234-13.
DOI Scopus46 WoS42 Europe PMC41
2018 Murphy, J., Ramezanpour, M., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2018). Mucosal zinc deficiency in chronic rhinosinusitis with nasal polyposis contributes to barrier disruption and decreases ZO-1. Allergy European Journal of Allergy and Clinical Immunology, 73(10), 2095-2097.
DOI Scopus27 WoS26 Europe PMC22
2018 Hamon, R., Tran, H. B., Roscioli, E., Ween, M., Jersmann, H., & Hodge, S. (2018). Bushfire smoke is pro-inflammatory and suppresses macrophage phagocytic function. Scientific Reports, 8(1), 13424-1-13424-11.
DOI Scopus24 WoS24 Europe PMC21
2018 Farrow, N., Donnelley, M., Cmielewski, P., Roscioli, E., Rout-Pitt, N., McIntyre, C., . . . Parsons, D. (2018). Role of basal cells in producing persistent lentivirus-mediated airway gene expression. Human Gene Therapy, 29(6), 653-662.
DOI Scopus17 WoS18 Europe PMC13
2017 Roscioli, E., Jersmann, H., Lester, S., Badiei, A., Fon, A., Zalewski, P., & Hodge, S. (2017). Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD. International Journal of Chronic Obstructive Pulmonary Disease, 12, 3503-3510.
DOI Scopus44 WoS40 Europe PMC36
2017 Hodge, S., Tran, H., Hamon, R., Roscioli, E., Hodge, G., Jersmann, H., . . . Wilbert, S. (2017). Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. American Journal of Physiology - Lung Cellular and Molecular Physiology, 312(5), L678-L687.
DOI Scopus51 WoS46 Europe PMC40
2017 Roscioli, E., Tran, H., Jersmann, H., Nguyen, P., Hopkins, E., Lester, S., . . . Hodge, S. (2017). The uncoupling of autophagy and zinc homeostasis in airway epithelial cells as a fundamental contributor to COPD. American Journal of Physiology - Lung Cellular and Molecular Physiology, 313(3), L453-L465.
DOI Scopus32 WoS29 Europe PMC26
2017 Tran, H., Jersmann, H., Truong, T., Hamon, R., Roscioli, E., Ween, M., . . . Hodge, S. (2017). Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. PLoS ONE, 12(11), e0179577-1-e0179577-14.
DOI Scopus30 WoS28 Europe PMC22
2017 Roscioli, E., Hamon, R., Ruffin, R., Grant, J., Hodge, S., Zalewski, P., & Lester, S. (2017). BIRC3 single nucleotide polymorphism associate with asthma susceptibility and the abundance of eosinophils and neutrophils. Journal of Asthma, 54(2), 116-124.
DOI Scopus12 WoS12 Europe PMC11
2016 Hodge, G., Roscioli, E., Jersmann, H., Tran, H. B., Holmes, M., Reynolds, P. N., & Hodge, S. (2016). Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes. RESPIRATORY RESEARCH, 17(1), 12 pages.
DOI Scopus30 WoS32 Europe PMC30
2016 Tran, H. B., Barnawi, J., Ween, M., Hamon, R., Roscioli, E., Hodge, G., . . . Hodge, S. (2016). Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. Journal of Leukocyte Biology, 100(1), 195-202.
DOI Scopus29 WoS29 Europe PMC26
2016 Barnawi, J., Tran, H. B., Roscioli, E., Hodge, G., Jersmann, H., Haberberger, R., & Hodge, S. (2016). Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(5), 653-661.
DOI Scopus22 WoS21 Europe PMC20
2015 Cantero, D., Cooksley, C., Bassiouni, A., Tran, H., Roscioli, E., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus biofilms induce apoptosis and expression of interferon-γ, interleukin-10, and interleukin-17A on human sinonasal explants. American Journal of Rhinology and Allergy, 29(1), 23-28.
DOI Scopus21 WoS18 Europe PMC12
2015 Malik, Z., Roscioli, E., Murphy, J., Ou, J., Bassiouni, A., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus impairs the airway epithelial barrier in vitro. International Forum of Allergy and Rhinology, 5(6), 551-556.
DOI Scopus62 WoS56 Europe PMC48
2015 Cooksley, C., Roscioli, E., Wormald, P., & Vreugde, S. (2015). TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells. Molecular Immunology, 68(2 part B), 476-483.
DOI Scopus20 WoS19 Europe PMC16
2015 Barnawi, J., Hai, T., Jersmann, H., Pitson, S., Roscioli, E., Hodge, G., . . . Hodge, S. (2015). Potential link between the Sphingosine-1-Phosphate (S1P) system and defective alveolar macrophage phagocytic function in Chronic Obstructive Pulmonary Disease (COPD). PLoS One, 10(10), e0122771-1-e0122771-21.
DOI Scopus50 WoS44 Europe PMC43
2015 Hodge, G., Jersmann, H., Tran, H., Roscioli, E., Holmes, M., Reynolds, P., & Hodge, S. (2015). Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes. Respiratory Research, 16(1), 130-1-130-11.
DOI Scopus36 WoS13 Europe PMC30
2014 Hamon, R., Homan, C., Tran, H., Mukaro, V., Lester, S., Roscioli, E., . . . Hodge, S. (2014). Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPD. PLoS ONE, 9(10), e110056-1-e110056-9.
DOI Scopus58 WoS58 Europe PMC49
2014 Tan, N., Cooksley, C., Roscioli, E., Drilling, A., Douglas, R., Wormald, P., & Vreugde, S. (2014). Small-colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis. Allergy, 69(10), 1364-1371.
DOI Scopus38 WoS38 Europe PMC35
2013 Roscioli, E., Hamon, R., Ruffin, R., Lester, S., & Zalewski, P. (2013). Cellular inhibitor of apoptosis-2 is a critical regulator of apoptosis in airway epithelial cells treated with asthma-related inflammatory cytokines. Physiological Reports, 1(5), e00123-1-e00123-11.
DOI Scopus13 WoS13 Europe PMC9
2013 Roscioli, E., Hamon, R., Lester, S., Murgia, C., Grant, J., & Zalewski, P. (2013). Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways. Biometals, 26(2), 205-227.
DOI Scopus19 WoS15 Europe PMC13
2013 Roscioli, E., Hamon, R., Ruffin, R., Zalewski, P., Grant, J., & Lester, S. (2013). X-linked inhibitor of apoptosis single nucleotide polymorphisms and copy number variation are not risk factors for asthma. Respirology, 18(4), 697-703.
DOI Scopus5 WoS5 Europe PMC3
2012 Tan, N. W., Tran, H., Roscioli, E., Wormald, P. J., & Vreugde, S. (2012). Prevention of false positive binding during immunofluorescence of Staphylococcus aureus infected tissue biopsies. Journal of Immunological Methods, 384(1-2), 111-117.
DOI Scopus8 WoS8 Europe PMC7
2011 Murgia, C., Grosser, D., TruongTran, A., Roscioli, E., Michalczyk, A., Ackland, M., . . . Zalewski, P. (2011). Apical localization of zinc transporter ZnT4 in human airway epithelial cells and its loss in a murine model of allergic airway inflammation. Nutrients, 3(11), 910-928.
DOI Scopus24 WoS22 Europe PMC18
2011 Lang, C., Hansen, M., Roscioli, E., Jones, J., Murgia, C., Ackland, M., . . . Ruffin, R. (2011). Dietary zinc mediates inflammation and protects against wasting and metabolic derangement caused by sustained cigarette smoke exposure in mice. Biometals, 24(1), 23-39.
DOI Scopus20 WoS19 Europe PMC15

Year Citation
2025 Liu, S., Chirstone, F., & Roscioli, E. (2025). TISSUE ENGINEERING IS REQUIRED FOR PREDICTIVE MODELS OF PERFLUOROCARBON EXPOSURE IN THE HUMAN AIRWAYS. In INTERNAL MEDICINE JOURNAL Vol. 55 (pp. 92). WILEY.
2025 Sabatini, I., & Roscioli, E. (2025). OVERCOMING THE ARREST OF AUTOPHAGY CAUSED BY AZITHROMYCIN: A CO-EXPOSURE MODEL OF THE AIRWAY EPITHELIUM. In INTERNAL MEDICINE JOURNAL Vol. 55 (pp. 93). WILEY.
2022 Alawami, M., Macowan, M., Delhove, J., Lester, S., Nguyen, P., Jersmann, H., . . . Roscioli, E. (2022). Sinonasal-airway epithelial cultures as surrogate models of the lower airway. In RESPIROLOGY Vol. 27 (pp. 72). WILEY.
2022 Roscioli, E., Kos, V., Kok, C., Sallustio, B., Kopp, B., & Blencowe, A. (2022). Overcoming off-target block of autophagy by azithromycin in epithelial cells. In RESPIROLOGY Vol. 27 (pp. 74). WILEY.
2021 Asare, P., Roscioli, E., Hurtado, P., Tran, H., & Hodge, S. (2021). INHIBITION OF LC3-ASSOCIATED PHAGOCYTOSIS (LAP) IN COPD AND IN RESPONSE TO CIGARETTE SMOKE. In RESPIROLOGY Vol. 26 (pp. 21-22). WILEY.
2018 Hodge, G., Jersmann, H., Tran, H., Hamon, R., Roscioli, E., Holmes, M., . . . Hodge, S. (2018). Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. In EUROPEAN RESPIRATORY JOURNAL Vol. 52 (pp. 2 pages). Paris, FRANCE: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
DOI
2018 Hai, T., Roscioli, E., Hamon, R., Ween, M., Hodge, G., Jersmann, H., & Hodge, S. (2018). Differential inflammasome activation in alveoli and bronchioles in response to cigarette smoke or double stranded DNA. In EUROPEAN RESPIRATORY JOURNAL Vol. 52 (pp. 2 pages). Paris, FRANCE: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
DOI

Year Citation
2023 Roscioli, E., Blencowe, A., Lester, S. E., Miller, M. M., Kos, V. M., Kopp, B. T., . . . Reynolds, P. N. (2023). Modification of azithromycin to counter its arrest of autophagy. Poster session presented at the meeting of Abstracts of the International Congress of European Respiratory Society (ERS 2023), as published in European Respiratory Journal. Milan, Italy and virtual online: European Respiratory Society (ERS).
DOI
2021 Poh, M., Roscioli, E., Fonceca, A., Kicic, A., Everard, M., & Waerp. (2021). NTHi HOST DEFENCE EVASION AS A RESULT OF POLYMICROBIAL INFECTION. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2020 Asare, P., Roscioli, E., Tran, B. H., & Hodge, S. (2020). POTENTIAL DYSREGULATION OF LC3-ASSOCIATED PHAGOCYTOSIS (LAP) BY CIGARETTE SMOKE EXPOSURE. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2020 Asare, P. F., Roscioli, E., Hurtado, P. R., Tran, H. B., Maiolo, S., & Hodge, S. (2020). THP-1 Macrophages Exposed to the Factors in Cigarette Smoke Exhibit Dysregulation of LC3-Associated Phagocytosis (LAP). Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. ELECTR NETWORK: AMER THORACIC SOC.
2019 Roscioli, E., Poh, M., Kicic, A., Lester, S. E., Nguyen, P., Jersmann, H. P. A., . . . Hodge, S. (2019). Nontypeable haemophilus influenzae (NTHi) exploits disease-related defects in xenophagy to persist and traffic within the epithelial compartment during COPD. Poster session presented at the meeting of American Journal of Respiratory and Critical Care Medicine. Dallas, TX: American Thoracic Society.
DOI
2018 Roscioli, E., Bac-Tran, H., Kicic, A., Poh, M., Jersmann, H., & Hodge, S. (2018). NONTYPEABLE HAEMOPHILUS INFLUENZAE (NTHI) EXPLOITS DEFECTS IN AIRWAY EPITHELIAL CELL XENOPHAGY AS A MEANS OF PERSISTENCE DURING COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2018 Roscioli, E., Hamon, R., Jersmann, H., & Hodge, S. (2018). SHORT TERM EXPOSURE TO WILDFIRE SMOKE EXTRACT POTENTIATES AUTOPHAGIC INSUFFICIENCY AND BARRIER DYSFUNCTION IN EX VIVO MODELS OF THE AIRWAY EPITHELIUM. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2018 Tran, H., Roscioli, E., Hamon, R., Ween, M., Hodge, G., Jersmann, H., & Hodge, S. (2018). DIFFERENTIAL NLRP3/AIM2 INFLAMMASOME ACTIVATION IN COPD AND RESPONSE TO CIGARETTE SMOKE. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2017 Hodge, S., Tran, H. B., Jersmann, H., Tung, T. T., Hamon, R., Roscioli, E., . . . Reynolds, P. N. (2017). Differential expression of the S1P transporter, Spinster homologue 2 (Spns2), in airway epithelial cells and macrophages may drive defective macrophage function in COPD. Poster session presented at the meeting of EUROPEAN RESPIRATORY JOURNAL. Milan, ITALY: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
DOI
2017 Roscioli, E., Hamon, R., Jersmann, H., Reynolds, P., & Hodge, S. (2017). Airway cells exposed to wildfire smoke extract exhibit dysregulation of autophagy and changes characteristic of inflammatory airway disease. Poster session presented at the meeting of EUROPEAN RESPIRATORY JOURNAL. Milan, ITALY: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
DOI WoS2
2017 Hamon, R., Hai, T., Roscioli, E., Jersmann, H., Reynolds, P. N., Wilbert, S., & Hodge, S. (2017). Non-antibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. Poster session presented at the meeting of Proceedings of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ)Annual Scientific Meeting, 2017, as published in Respirology. Canberra, ACT: Wiley.
2017 Roscioli, E., Bac-Tran, H., Jersmann, H., Hodge, G., Hopkins, E., Hamon, R., . . . Hodge, S. (2017). Zinc dyshomeostasis and autophagy as critical determinants for airway epithelial dysfunction in COPD. Poster session presented at the meeting of Proceedings of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ)Annual Scientific Meeting, 2017, as published in Respirology. Canberra, ACT: Wiley.
2017 Roscioli, E. (2017). Defective xenophagic destruction of potentially pathogenic bacteria by airway epithelial cells in COPD. Poster session presented at the meeting of TSANZ Annual Scientific Meeting 2017. Canberra.
2016 Tran, H., Hamon, R., Roscioli, E., Ween, M., Hodge, G., Jersmann, H., . . . Hodge, S. (2016). CIGARETTE SMOKE INDUCED MULTIPLE INFLAMMASOME ACTIVATION AND ANTI-INFLAMMATORY EFFECTS OF S1P AND FTY720 SUGGEST NOVEL TARGETS IN COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016 Roscioli, E., Bac-Tran, H., Hamon, R., Zalewski, P., & Hodge, S. J. (2016). Association Of Increased Autophagy In COPD And Dysregulation Of Zinc Handling Systems. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. San Francisco, CA: AMER THORACIC SOC.
2016 Roscioli, E., Bac-Tran, H., Hamon, R., Zalewski, P., Hodge, G., Reynolds, P., & Hodge, S. (2016). AUTOPHAGY-RELATED EPITHELIAL DISINTEGRATION IN AN EX VIVO MODEL OF COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016 Tran, H., Barnawi, J., Ween, M., Hamon, R., Roscioli, E., Hodge, G., . . . Hodge, S. (2016). CHANGED INTRACELLULAR LOCALIZATION OF SPHINGOSINE KINASES BY CIGARETTE SMOKE IN MACROPHAGES MAY CONTRIBUTE TO DEFECTIVE PHAGOCYTIC FUNCTION. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016 Tran, H., Hamon, R., Ween, M., Hodge, G., Roscioli, E., Barnawi, J., . . . Hodge, S. (2016). DIFFERENTIAL SUBCELLULAR LOCALIZATION AND EXPRESSION OF SPINSTER HOMOLOG 2 (DROSOPHILA) IN AIRWAY EPITHELIAL CELLS AND MACROPHAGES IN RESPONSE TO CIGARETTE SMOKE AND IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE MAY CONTRIBUTE TO MACROPHAGE PHAGOCYTIC DYSFUNCTION. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016 Hamon, R., Roscioli, E., Jersmann, H., & Hodge, S. (2016). BUSHFIRE SMOKE AND ITS EFFECTS ON AIRWAY CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016 Hodge, G., Jersman, H., Holmes, M., Roscioli, E., Tran, H., Reynolds, P., & Hodge, S. (2016). STEROID RESISTANCE IN COPD IS ASSOCIATED WITH IMPAIRED MOLECULAR CHAPERONE HSP90 EXPRESSION BY PRO-INFLAMMATORY LYMPHOCYTES. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2015 Tran, H., Zalewski, P., Roscioli, E., Barnawi, J., Hodge, G., Reynolds, P., & Hodge, S. (2015). ZINC DYSHOMEOSTASIS IS LINKED TO DEFECTIVE LUNG MACROPHAGE PHAGOCYTIC FUNCTION AND AIRWAY INFLAMMATION IN MICE EXPOSED TO CIGARETTE SMOKE. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015 Roscioli, E., Tran, H., Zalewski, P., Hodge, G., Carrol, A., Rix, S., . . . Hodge, S. (2015). ZINC HANDLING SYSTEM AND AUTOPHAGY IN COPD. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015 Roscioli, E., Hamon, R., Ruffin, R., Zalewski, P., Hodge, S., Grant, J., & Lester, S. (2015). BIRC2 SINGLE NUCLEOTIDE POLYMORPHISMS MODULATE THE SEVERITY OF ASTHMA IN A CAUCASIAN COMMUNITY-BASED COHORT. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015 Lau, A., Bosco, M., Lester, S., Roscioli, E., Zalewski, P., & Rischmueller, M. (2015). ARA3 Inflammasome activation in salivary gland epithelial cells - a disease model for primary sjögren's syndrome. Poster session presented at the meeting of Abstracts of the Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, as published in Internal Medicine Journal. Adelaide, South Australia: Wiley.
DOI
2015 Hodge, G., Jersmann, H., Holmes, M., Reynolds, P., & Hodge, S. (2015). LYMPHOCYTE SENESCENCE IN COPD IS ASSOCIATED WITH DECREASED HISTONE DEACETYLASE 2 EXPRESSION BY PRO-INFLAMMATORY LYMPHOCYTES. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2014 Tran, H., Roscioli, E., Tan, N., Cooksley, C., Zalewski, P., Wormald, P., & Vreudge, S. (2014). ABSENT IN MELANOMA 2 (AIM2) INFLAMMASOME ACTIVATION IN SINUS EPITHELIUM OF ASTHMATIC CHRONIC RHINOSINUSITIS PATIENTS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2010 Hamon, R., Roscioli, E., Lang, C., Murgia, C., Ruffin, R., & Zalewski, P. (2010). Zinc Chelation Induced Depletion Of X-Linked Inhibitor Of Apoptosis Protein (XIAP) In Airway Epithelial Cells. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Year Citation
2024 Quarrington, R., Sapula, S., Lester, S., Miller, M., Munic Kos, V., Kopp, B., . . . Roscioli, E. (2024). Modification of Azithromycin to Mitigate its Arrest of Autophagy.
DOI
2024 Liu, S., Christone, F., Quarrington, R., & Roscioli, E. (2024). Organotypic tissue architecture is a requisite for predictive outcomes of perfluorocarbon exposure in airway models.
DOI

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor Photoaffinity labeling approach to elucidate azithromycin host-directed mechanisms and mitigating off-target effects with novel therapeutics Doctor of Philosophy Doctorate Full Time Mr Shawn Wen Han Liu
2025 Principal Supervisor A novel approach to measure and target the dysregulation of autophagy in Chronic Obstructive Pulmonary Disease Master of Philosophy (Medical Science) Master Full Time Miss Shiye Chen

Date Role Research Topic Program Degree Type Student Load Student Name
2020 - 2025 Co-Supervisor An Investigation into the Mechanisms of Persistence Utilised by Intra-Osteocytic Staphylococcus aureus Doctor of Philosophy Doctorate Full Time Mr Nicholas James Gunn
2018 - 2022 Co-Supervisor An investigation of the Rubicon/LC3 associated phagocytosis (LAP) dysregulation as a therapeutic target in chronic obstructive pulmonary diseases (COPD) and in response to cigarette smoke exposure Doctor of Philosophy Doctorate Full Time Dr Patrick Fordjour Asare

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2025 - ongoing Principal Supervisor Assessment of next generation azithromycin derivatives in models of the human airway The University of Adelaide Bchelor of Health and Medical Sciences Honours Full Time Duc Quang Doan
2024 - ongoing Principal Supervisor Antibiotic perfluorocarbon emulsion delivery in airway models The University of Adelaide Biotechnology, School of Biological Sciences; Faculty of Sciences, Engineering and Technology Master Full Time Dishant Patel
2024 - 2024 Principal Supervisor Co-treatment strategies to mitigate azithromycin's off-target block of autophagy The University of Adelaide Biotechnology, School of Biological Sciences; Faculty of Sciences, Engineering and Technology Master Full Time Izabella R Sabatini
2024 - 2024 Principal Supervisor Organotypic tissue architecture is a requisite for predictive outcomes of perfluorocarbon exposure in airway models The University of Adelaide Science; School of Biological Sciences; Faculty of Sciences, Engineering and Technology Honours Full Time Shawn W Liu
2021 - 2021 Principal Supervisor Overcoming azithromycin's block of autophagy by using autophagy promoters in Chronic Obstructed Pulmonary Disease models The University of Adelaide Biotechnology, School of Biological Sciences; Faculty of Sciences, Engineering and Technology Master Full Time Harpreet Kaur
2017 - 2025 Co-Supervisor The role of persistent lifestyles of Staphylococcus aureus in bone infections The University of Adelaide Surgery Specialties Doctorate Full Time Nicholas James Gunn

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