Patrick Asare

Dr Patrick Asare

NHMRC Ext-Funded Rsch Fellow B

School of Medicine

College of Health

Eligible to supervise Masters and PhD as Co-Supervisor only - email supervisor to discuss availability.


Summary

Dr Patrick Asare is a translational respiratory researcher and Team Leader of the Chronic Inflammatory Lung Disease Laboratory at Adelaide University. A pharmacist by training, his research focuses on chronic respiratory diseases including chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), interstitial lung disease and environmental lung injury.
His work integrates clinical trials, human biospecimens, molecular and cellular models, proteomics and biomarker development, with a focus on translating mechanistic discoveries into clinically relevant interventions and tools. He currently supervises two PhD students and leads multidisciplinary research involving clinicians, laboratory scientists, consumers and external research partners.

Research experience

Dr Asare has developed an independent translational research program spanning COPD, CF and related inflammatory lung diseases. He conceived and leads an MRFF-funded randomised controlled trial investigating zinc supplementation in COPD and its linked biomarker program, with responsibility for scientific direction, clinical coordination, recruitment, laboratory workflows, governance and consumer engagement.
He has also established a CF research program arising from paediatric airway proteomics and extending into biomarker development, airway stress and remodelling, ageing-associated biology and mechanistic epithelial studies. His research has involved collaborations across Adelaide University, CALHN/Royal Adelaide Hospital, the Women’s and Children’s Hospital and QIMR Berghofer Medical Research Institute.
Dr Asare has secured more than AUD $2 million in competitive research funding as CIA/PI/CI, including more than AUD $1.1 million as lead investigator. His broader academic contribution includes postgraduate supervision, multidisciplinary team leadership, national grant assessment through NHMRC and MRFF, editorial and peer-review service, and consumer-engaged research.

Areas of expertise

Chronic respiratory disease | Translational respiratory research | Clinical trials | Biomarker development | Proteomics | Human biospecimen research | Molecular and cellular respiratory biology | Preclinical models | Multidisciplinary research leadership | Consumer-engaged research.

Research and technical capabilities

Clinical trial design and management | Participant recruitment and clinical research coordination | Flow cytometry | Cell culture and airway epithelial models | Western blotting | RT-qPCR | ELISA | Proteomics | Microscopy | Molecular biology | Animal/preclinical studies | Data analysis and interpretation | Scientific writing | Grant development | Project management | Stakeholder engagement

Research outputs

20 published journal articles and 1 accepted manuscript, together with 8 conference outputs. Two further manuscripts are currently under revision. His research has received more than 750 citations, with an h-index of 14.

Evidence of success and emerging reputation in the field:

  • 2025 - MRFF Early to Mid-Career Researchers Grant – CI, AUD $980,783
  • 2024 - Derek Frewin Early Career Research Fellowship – PI, AUD $5,000
  • 2024 - Adelaide Medical School Equipment Grant – PI, AUD $9,311
  • 2023 - MRFF Early to Mid-Career Researchers Grant – CIA, AUD $990,064
  •  2023 - QIMR Berghofer/CALHN environmental lung-health project funding – PI
  • 2022 - Dean’s Commendation for Doctoral Thesis Excellence, University of Adelaide
  • 2020 - TSANZ South Australia New Investigator Award
  • 2020 - Royal Adelaide Hospital Medical Staff Society Research Prize

Collaborations

Dr Asare has established multidisciplinary collaborations across Adelaide University, CALHN/Royal Adelaide Hospital, the Women’s and Children’s Hospital and QIMR Berghofer Medical Research Institute. These collaborations bring together expertise in respiratory medicine, paediatric CF, proteomics, mass spectrometry, environmental exposure biology and translational biomedical research, enabling access to clinically characterised biospecimens, advanced analytical platforms, publications, preliminary datasets and competitive grant development.

Consumer and community engagement

Dr Asare integrates consumer perspectives into the design and delivery of his translational respiratory research. He established and chairs a COPD Advisory Group comprising respiratory clinicians and people living with COPD, providing a structured mechanism for clinical and lived-experience input into research implementation.
He has also established engagement with Lung Foundation Australia to support participant recruitment and community engagement and is extending consumer involvement into his cystic fibrosis research through engagement with people living with CF and Cystic Fibrosis South Australia. This approach supports the development of research that is clinically relevant, feasible and responsive to the priorities of people affected by chronic respiratory disease.

Contribution to research, training and the profession

Dr Asare currently supervises two PhD students and has previously supervised or co-supervised undergraduate and Master’s research students. He provides research direction, experimental design support, data interpretation, scientific writing guidance and career development to students and junior researchers.
He contributes nationally to research assessment, having reviewed 33 NHMRC Ideas Grant applications across 2025 and 2026 and served in leadership roles on MRFF Grant Assessment Committees, including Chair and Assistant Chair. He also serves as a Review Editor for Frontiers in Oncology and undertakes peer review for journals in inflammation, respiratory and cellular biology.
His contribution to research culture includes leadership of multidisciplinary research activities, mentoring of junior researchers, development of reusable research resources and integration of clinicians and consumers into translational respiratory research.

Society memberships and affiliations

  • 2018-present: Thoracic Society of Australia and New Zealand
  • 2019-present: American Thoracic Society
  • 2022-present: University of Adelaide Alumni

Date Institution name Country Title
2018 - 2022 University of Adelaide Australia PhD in Medicine
2013 - 2016 Tianjin University of Traditional Chinese Medicine China Master's in Medicine
2008 - 2012 University of Ghana Ghana Bachelor of Pharmacy

Year Citation
2026 Asare, P. F., Reisen, F., Elkaee, S., Li, Z., Hu, W. -P., Vivian, E. R., . . . Quek, H. (2026). Multi-Element ICP-MS Profiling of Bushfire Smoke Preparations for Composition-Based Exposure Characterization. Fire, 9(10), 425-1-425-27.
DOI
2024 Asare, P. F., Jayapal, M., Tai, A., Maiolo, S., Chapman, S., Morton, J., . . . Tran, H. B. (2024). Mechanisms underlying the roles of leukocytes in the progression of cystic fibrosis. Experimental Lung Research, 50(1), 208-220.
DOI
2023 Asare, P. F., Hurtado, P. R., Tran, H. B., Perkins, G. B., Roscioli, E., & Hodge, S. (2023). Reduction in Rubicon by cigarette smoke is associated with impaired phagocytosis and occurs through lysosomal degradation pathway. Clinical and Experimental Medicine, 23(7), 4041-4055.
DOI Scopus6 WoS6 Europe PMC5
2023 Hodge, G., Jersmann, H., Holmes, M., Asare, P., Roscioli, E., Reynolds, P. N., & Hodge, S. (2023). BLTR1 Is Decreased in Steroid Resistant Pro-Inflammatory CD28nullCD8+ T Lymphocytes in Patients with COPD—The Spillover Hypothesis Explained?. Biology, 12(9), 1261-1-1261-13.
DOI Scopus3 WoS2 Europe PMC3
2022 Hodge, G., Jersmann, H., Tran, H. B., Asare, P. F., Jayapal, M., Reynolds, P. N., . . . Hodge, S. (2022). COPD is associated with increased pro-inflammatory CD28null CD8 T and NKT-like cells in the small airways. Clinical and Experimental Immunology, 207(3), 351-359.
DOI Scopus14 WoS13 Europe PMC12
2022 Agyemang, K., Johansen, A. M., Barker, G. W., Pennison, M. J., Sheffield, K., Jimenez, H., . . . Pasche, B. (2022). TGFBR1*6A as a modifier of breast cancer risk and progression: advances and future prospects. npj Breast Cancer, 8(1), 84-1-84-9.
DOI Scopus6 WoS5 Europe PMC6
2022 Tran, H. B., Jakobczak, R., Abdo, A., Asare, P., Reynolds, P., Beltrame, J., . . . Zalewski, P. (2022). Immunolocalization of zinc transporters and metallothioneins reveals links to microvascular morphology and functions. Histochemistry and Cell Biology, 158(5), 485-496.
DOI Scopus10 WoS9 Europe PMC8
2021 Asare, P. F., Tran, H. B., Hurtado, P. R., Perkins, G. B., Nguyen, P., Jersmann, H., . . . Hodge, S. (2021). Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke. Therapeutic Advances in Respiratory Disease, 15, 17534666211039769-1-17534666211039769-15.
DOI Scopus26 WoS22 Europe PMC25
2021 Tran, H. B., Hamon, R., Jersmann, H., Ween, M. P., Asare, P., Haberberger, R., . . . Hodge, S. J. (2021). AIM2 nuclear exit and inflammasome activation in chronic obstructive pulmonary disease and response to cigarette smoke. Journal of Inflammation-London, 18(1), 1-13.
DOI Scopus16 WoS15 Europe PMC15
2020 Asari, P., Roscioli, E., Hurtado, P., Tran, H., Mah, C., & Hodge, S. (2020). LC3-associated phagocytosis (LAP): a potentially influential mediator of efferocytosis-related tumour progression and aggressiveness.. Frontiers in Oncology-Molecular and Cellular Oncology, 10, 1298-1-1298-14.
DOI Scopus46 WoS42 Europe PMC43
2017 Wang, L., Yu, J., Fordjour, P. A., Xing, X., Gao, H., Li, Y., . . . Fan, G. (2017). Danshen injection prevents heart failure by attenuating post-infarct remodeling. Journal of Ethnopharmacology, 205, 22-32.
DOI Scopus56 WoS54 Europe PMC47
2017 Xiaoyan, W., Pais, E. M. A., Lan, L., Jingrui, C., Lin, M., Asare, P., & Guanwei, F. (2017). MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases. Inflammation, 40(2), 708-716.
DOI Scopus28 WoS30 Europe PMC25
2016 Xing, X., Su, L., Asare, P. F., Wang, L., Li, L., Liu, E., . . . Fan, G. (2016). Danzhi Qing'e (DZQE) activates AMPK pathway and regulates lipid metabolism in a rat model of perimenopausal hyperlipidaemia. Experimental Physiology, 101(11), 1406-1417.
DOI Scopus12 WoS10 Europe PMC11
2016 Chen, J., Cao, W., Asare, P. F., Lv, M., Zhu, Y., Li, L., . . . Fan, G. (2016). Amelioration of cardiac dysfunction and ventricular remodeling after myocardial infarction by danhong injection are critically contributed by anti-TGF-β-mediated fibrosis and angiogenesis mechanisms. Journal of Ethnopharmacology, 194, 559-570.
DOI Scopus57 WoS53 Europe PMC47
2016 Fan, G., Yu, J., Asare, P. F., Wang, L., Zhang, H., Zhang, B., . . . Gao, X. (2016). Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling. Journal of Cellular and Molecular Medicine, 20(10), 1908-1919.
DOI Scopus87 WoS78 Europe PMC70
2016 Gao, H., Li, L., Li, L., Gong, B., Dong, P., Fordjour, P. A., . . . Fan, G. (2016). Danshensu Promotes Cholesterol Efflux in RAW264.7 Macrophages. Lipids, 51(9), 1083-1092.
DOI Scopus37 WoS34 Europe PMC29
2016 Fordjour, P. A., Wang, L., Gao, H., Li, L., Wang, Y., Nyagblordzro, M., . . . Fan, G. (2016). Targeting BNIP3 in inflammation-mediated heart failure: a novel concept in heart failure therapy. Heart Failure Reviews, 21(5), 489-497.
DOI Scopus19 WoS19 Europe PMC20
2016 Fan, G., Jiang, X., Wu, X., Fordjour, P. A., Miao, L., Zhang, H., . . . Gao, X. (2016). Anti-Inflammatory Activity of Tanshinone IIA in LPS-Stimulated RAW264.7 Macrophages via miRNAs and TLR4–NF-κB Pathway. Inflammation, 39(1), 375-384.
DOI Scopus107 WoS107 Europe PMC82
2015 Liu, W., Wang, L., Yu, J., Asare, P. F., & Zhao, Y. Q. (2015). Gastrodin reduces blood pressure by intervening with RAAS and PPAR γ in SHRs. Evidence Based Complementary and Alternative Medicine, 2015, 8 pages.
DOI Scopus46 WoS30 Europe PMC27
2015 Fordjour, P. A., Wang, Y., Shi, Y., Agyemang, K., Akinyi, M., Zhang, Q., & Fan, G. (2015). Possible mechanisms of C-reactive protein mediated acute myocardial infarction. European Journal of Pharmacology, 760, 72-80.
DOI Scopus52 WoS50 Europe PMC41

Year Citation
2025 Asare, P., White, A., Quek, H., Reisen, F., Jersmann, H., & Reynolds, P. (2025). IMPACT OF BUSHFIRE SMOKE EXTRACT ON MACROPHAGE FUNCTION AND INFLAMMATION: IMPLICATIONS FOR RESPIRATORY HEALTH. In INTERNAL MEDICINE JOURNAL Vol. 55 (pp. 13-14). WILEY.
2025 Asare, P., White, A., Quek, H., Reisen, F., Jersmann, H., & Reynolds, P. (2025). Impact of bushfire smoke extract on macrophage function and inflammation: Implications for respiratory health. In EUROPEAN RESPIRATORY JOURNAL Vol. 66 (pp. 3 pages). NETHERLANDS, Amsterdam: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
DOI
2023 Asare, P., Tran, H., Tai, A., Chapman, S., Morton, J., Reynolds, P., & Hodge, S. (2023). Mechanisms underlying roles of leukocytes in progression of cystic fibrosis. In RESPIROLOGY Vol. 28 (pp. 159). WILEY.

Year Citation
2026 Quek, H., Asare, P., Vivian, E. R., Kim, D., Etebar, F., Cuni-Lopez, C., . . . White, A. R. (2026). Redox biology of wildfire smoke and impacts on human health. Poster session presented at the meeting of Abstracts of the Society for Free Radical Research Europe (SFRR-E2026) as published in Free Radical Biology and Medicine. US: Elsevier BV.
DOI
2021 Asare, P., Roscioli, E., Hurtado, P., Tran, H., & Hodge, S. (2021). INHIBITION OF LC3-ASSOCIATED PHAGOCYTOSIS (LAP) IN COPD AND IN RESPONSE TO CIGARETTE SMOKE. Poster session presented at the meeting of Abstracts of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science (TSANZSRS 2021) as published in Respirology. Australia: Wiley.
2020 Asare, P. F., Roscioli, E., Hurtado, P. R., Tran, H. B., Maiolo, S., & Hodge, S. (2020). THP-1 Macrophages Exposed to the Factors in Cigarette Smoke Exhibit Dysregulation of LC3-Associated Phagocytosis (LAP). Poster session presented at the meeting of Abstracts of the International Conference of the American-Thoracic-Society (ATS 2020), as published in the American Journal of Respiratory and Critical Care Medicine. US: Oxford Academic.
DOI
2019 Hodge, S., Rosciolo, E., Tran, H., & Asare, P. (2019). LC3-ASSOCIATED PHAGOCYTOSIS (LAP) IN COPD AND IN RESPONSE TO CIGARETTE SMOKE. Poster session presented at the meeting of Abstracts of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting (TSANZSRS 2019), as published in Respirology. Australian: John Wiley & Sons, Inc..

Year Citation
2024 Asare, P. F., Hodge, G., Ween, M., Hamon, R., Truong, T. T., Jersmann, H., . . . Tran, H. B. (2024). Double Targeting Inflammasome Activation and Accelerated Cellular Senescence in Alveolar Macrophages Exposed to Cigarette Smoke and COPD.
DOI
2024 Cuní-López, C., Ng, M. F., Stewart, R., Milton, L. A., Etebar, F., Sun, Y., . . . Quek, H. (2024). Impact of wildfire smoke and diesel exhaust on inflammatory response in aging human microglia.
DOI
  • 2025 - MRFF Early to Mid-Career Researchers Grant ($980,783)
  • 2024 - Derek Frewin Early Career Early Career Fellowship ($5,000)
  • 2023 - MRFF Early to Mid-Career Researchers Grant ($990,064)
  • 2023 - Queensland Institute of Medical Research ($110,714) 

Date Role Research Topic Program Degree Type Student Load Student Name
2026 Co-Supervisor Investigating Multi-Omics Factors Underlying Healthy Ageing Index (Human Intrinsic Capacity) Doctor of Philosophy Doctorate Full Time Miss Goodness Chizorom Nwokebu
2025 Co-Supervisor Repurposing mTOR inhibitors to improve immunological response to vaccination in older adults. Doctor of Philosophy Doctorate Full Time Ms Deborah Pratt

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