Dr Melissa Middeldorp
School of Medicine
College of Health
Dr Middeldorp completed her PhD in May 2019, with a focus on risk factors for Atrial Fibrillation. She moved to the United States in July 2021 to undertake a postdoctoral fellowship at Cedar Sinai Medical Centre, Los Angeles and is currently at the University Medical Centre Groningen, Netherlands. In May 2022 she graduated with her Masters in Public Health at Harvard University. Her research focus on the management of cardiovascular risk factors in patients with atrial fibrillation through individualised, structured clinics. Additionally, her research is focusing on the differences in outcomes between men and women with atrial fibrillation particularly outcomes, complications and treatment strategies.
Dr Middeldorp is a research scientist with a particular interest in:
1. Risk factors and the relationship with atrial fibrillation.
2. Gender differences in atrial fibrillation outcomes.
3. Ablation outcomes in patients with atrial fibrillation.
AVAILABLE PROJECTS FOR HONOURS/PHD STUDENTS
Below is a list of several projects available within our group. This list is not exhaustive and any prospective students should contact Dr Middeldorp in the first instance:
1. Atrial Fibrillation and Risk Factor Clinics.
Investigating the role of dedicated risk factor clinics to manage patients individual risk factors to improve symptoms, reversal of the disease process and outcomes in patients with atrial fibrillation.
2. Is There a Role that Gender Plays in Patients with Atrial Fibrillation.
There is much discrepancy in the role gender plays particularly regarding ablation outcomes. Currently we are running an ongoing registry of ablation patients to be able to distinguish if there is a difference and what particularly in the long term.
| Date | Position | Institution name |
|---|---|---|
| 2023 - ongoing | Postdoctoral Research Fellow | University Medical Centre of Groningen |
| 2021 - 2023 | Postdoctoral Research Fellow | Cedars-Sinai Medical Center |
| 2019 - 2021 | Postdoctoral Research Fellow | University of Adelaide |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2024 | Scholarship | HRX Allied Professional Travel Scholarship | Heart Rhythm Society | United States | - |
| 2023 | Award | Circulation Journal Outstanding Reviewer Award | American Heart Association | United States | - |
| 2023 | Award | European Heart Journal Top Reviewer Award | European Heart Journal | France | - |
| 2023 | Award | Highest Scoring Women in EP Abstract award | Heart Rhythm Society | United States | - |
| 2022 | Award | European Heart Journal Top Reviewer Award | European Heart Society | Spain | - |
| 2021 | Fellowship | Cedar-Sinai Postdoctoral Fellowship | Cedar-Sinai Medical Centre, Smit Heart Institute | United States | - |
| 2020 | Award | SA Science Excellence and Innovation PhD Excellence Award - Finalist | Government of South Australian - Department for Skills and Innovation | Australia | - |
| 2019 | Scholarship | European Society of Cardiology Educational Grant | European Society of Cardiology | France | - |
| 2019 | Award | Dean's Commendation for Doctoral Thesis Excellence | University of Adelaide | Australia | - |
| 2018 | Award | Medical Staff Society Research Prize | Royal Adelaide Hospital | Australia | - |
| 2018 | Award | AHM Research Travel Award | University of Adelaide | Australia | - |
| 2017 | Award | Best Moderated Poster Award – AF Ablation outcomes and predictors | ESC - European Society of Cardiology Congress | Spain | - |
| 2017 | Award | EO Myers Trust Fund Travel Scholarship | National Heart Foundation | Australia | - |
| 2015 | Scholarship | Robert J. Craig Scholarship | University of Adelaide | Australia | - |
| 2013 | Award | Highest Scoring Abstract in Allied Health | Heart Rhythm Society | United States | - |
| Language | Competency |
|---|---|
| English | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2022 | Harvard University, Harvard T Chan School of Public Health | United States | MPH |
| 2019 | University of Adelaide | Australia | PhD |
| Date | Title | Institution name | Country |
|---|---|---|---|
| 2009 | Certificate IV in Emergency Care | SA Ambulance Service | Australia |
| 2009 | Certificate II in Emergency - Medical service first response | SA Ambulance Service | Australia |
| 2006 | Certificate III in Business Administration | Buisness SA | Australia |
| Year | Citation |
|---|---|
| 2024 | Fitzgerald, J., Shahmohamadi, E., Emami, M., Middeldorp, M., Elliott, A., Gallagher, C., . . . Sanders, P. (2024). Intensive Risk Factor Modification for Secondary Prevention of Ischemic Stroke - a Feasibility Study. In CIRCULATION Vol. 150 (pp. 2 pages). IL, Chicago: LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2024 | Dziano, J., Howie, J., Ariyaratnam, J., Middeldorp, M., Emami, M., Mishima, R., . . . Elliott, A. (2024). Abnormalities in Cardiopulmonary Exercise Test Associated With More Advance Atrial Cardiomyopathy. In Heart Lung and Circulation Vol. 33 (pp. S146-S147). Elsevier BV. DOI |
| 2024 | Shahmohamadi, E., Middeldorp, M., Ariyaratnam, J., Jayakumar, M., Fitzgerald, J., Elliott, A., & Sanders, P. (2024). Ethnic differences in Body Mass Index Cut-off Values Associated with Cardiovascular Risks in South Asians Compared to White Population: A Systematic Review and Meta-analysis. In CIRCULATION Vol. 150 (pp. 3 pages). IL, Chicago: LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2023 | Mao, J., Middeldorp, M., Moorthy, M. V., Siddiqi, H. K., Sandhu, R. K., Cheng, S., . . . Albert, C. M. (2023). PREDICTORS OF NEW ONSET ASYMPTOMATIC ATRIAL FIBRILLATION: A VITAL RHYTHM STUDY. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 81 (pp. 124). LA, New Orleans: ELSEVIER SCIENCE INC. |
| 2023 | Middeldorp, M., Sandhu, R. K., Mao, J., Gencer, B., Danik, J. S., Moorthy, M. V., . . . Albert, C. M. (2023). RISK FACTORS ASSOCIATED WITH INCIDENT PERSISTENT ATRIAL FIBRILLATION AT TIME OF DIAGNOSIS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 81 (pp. 137). LA, New Orleans: ELSEVIER SCIENCE INC. |
| 2021 | Gallagher, C., Rowett, D., Nyfort-Hansen, K., Simmons, S., Bulto, L., Middeldorp, M. E., . . . Hendriks, J. M. (2021). Development and validation of a questionnaire to assess knowledge in patients with Atrial Fibrillation. In EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING Vol. 20 (pp. 7). OXFORD UNIV PRESS. DOI |
| 2020 | Walfridsson, U., Middeldorp, M., Walfridsson, H., Sanders, P., & Arestedt, K. (2020). Validation of the English version of the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA). In EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING Vol. 19 (pp. S41). SAGE PUBLICATIONS LTD. |
| 2017 | Mahajan, R., Lew, L., Koh, Y. H., Khokkar, K., Elliott, A. D., Gallagher, C., . . . Sanders, P. (2017). Cognitive impairment and dementia in atrial fibrillation: a meta-analysis. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 984). OXFORD UNIV PRESS. |
| 2017 | Ramkumar, S., Yang, H., Middeldorp, M., Sanders, P., & Marwick, T. H. (2017). Use of left atrial strain for risk stratification in atrial fibrillation with low clinical thromboembolic risk. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 884-885). OXFORD UNIV PRESS. |
| 2017 | Middeldorp, M. E., Elliott, A. D., Gallagher, C., Hendricks, J., Munawar, A., Khokhar, K., . . . Sanders, P. (2017). The influence of gender on 1-year outcomes of patients undergoing primary AF ablation. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 39). Barcelona, SPAIN: OXFORD UNIV PRESS. |
| 2015 | Wong, C. X., Sullivan, T., Sun, M. T., Mahajan, R., Pathak, R. K., Middeldorp, M., . . . Sanders, P. (2015). Body mass index and recurrent atrial fibrillation following catheter ablation: a meta-analysis. In EUROPEAN HEART JOURNAL Vol. 36 (pp. 737-738). London, ENGLAND: OXFORD UNIV PRESS. |
| 2015 | Pathak, R. K., Middeldorp, M. E., Stolcman, S., Willoughby, S., Mahajan, R., Lau, D. H., & Sanders, P. (2015). Aggressive Risk factor REduction STudy: Implications for the Substrate for Atrial Fibrillation (ARREST-AF Substrate Study). In CIRCULATION Vol. 132 (pp. 4 pages). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. WoS4 |
- Title: Centre of Research Excellence for Atrial Fibrillation (AF-CARE) to Reduce Burden of Disease
- Start date: 27 Jan 2026
- End date: 31 Dec 2030
- Funding scheme: NHMRC - Centres of Research Excellence
- Funder: National Health and Medical Research Council
- Total Awarded Amount: AUD $3,000,000
- Co-investigator
- Title: Establishing the Atrial Fibrillation Ablation National Cardiac Registry (AF-NCR)
- Start Date: 01 Apr 2025
- End date: 31 Mar 2031
- Funding Scheme: MRFF Enhancing Medical Device Surveillance Through Registries
- Funder: National Health and Medical Research Council
- Total Awarded Amount: AUD 6,999,911.6
- Co-investigator
- Title: Increasing Pacing Rate Amongst Patients with Heart Failure with Preserved Ejection Fraction: the PACE-UP Study
- Start date: 01 Jan 2024
- End date: 31 Dec 2025
- Funding scheme: Heart Foundation - Vanguard Grants
- Funder name: National Heart Foundation of Australia
- Total Awarded Amount: AUD $148,800
- Co-investigator
- Title: Improving Acute Atrial Fibrillation Management for better patient outcomes
- Start date: 01 Apr 2022
- End date: 31 Mar 2025
- Funding scheme: FND000838: MRFF - Emerging Priorities & Consumer Driven Research Initiative
- Funder name: National Health and Medical Research Council
- Total Awarded Amount: AUD $999,996
- Co-investigator
- Title: Epidemiology, risk factors, progression and AF
- Start Date: 01 Jul 2021
- End date: 30 Jun 2022
- Funding Scheme: AAUW International Postdoctoral Fellowship
- Funder: American Association for University Women
- Total Awarded Amount: USD $30,000
- Primary investigator
- Title: HRS Afib Awareness
- Start Date: 12 Sep 2016
- End date: 18 Sep 2016
- Funding Scheme: Afib Awareness Funding Grant
- Funder: Heart Rhythm Society
- Total Awarded Amount: USD $5,000
- Primary investigator
- Title: Weight and risk factor management and assessment of socioeconomic status to assess impact on AF progression
- Start date: 1 Jan 2017
- End date: 31 Dec 2019
- Funding scheme: NHMRC - Postgraduate Scholarships Grant
- Funder: National Health and Medical Research Council
- Total Awarded Amount: AUD $86,117.00
- Primary investigator
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | GEN-REF Study - Gender-based differences in referral to catheter ablation study | Doctor of Philosophy | Doctorate | Full Time | Ms Melanie Gunawardene |
| 2025 | Co-Supervisor | Efficacy of Combined Risk Factor Interventions for Atrial Fibrillation | Master of Philosophy (Clinical Science) | Master | Full Time | Dr Hidehiro Iwakawa |
| 2025 | Co-Supervisor | GEN-REF Study - Gender-based differences in referral to catheter ablation study | Doctor of Philosophy | Doctorate | Full Time | Ms Melanie Gunawardene |
| 2025 | Co-Supervisor | Efficacy of Combined Risk Factor Interventions for Atrial Fibrillation | - | Master | Full Time | Dr Hidehiro Iwakawa |
| 2024 | Co-Supervisor | PREDICTive value of aggressive risk factor modification on the occurrence of major cardiovascular events in patients with embolic STROKE (PREDICT-STROKE) | Doctor of Philosophy | Doctorate | Full Time | Dr Elnaz Shahmohamadi |
| 2024 | Co-Supervisor | Redesigning care with an Emergency Department protocol and rapid access clinic to reduce hospitalisations for Atrial Fibrillation (REDUCE-AF) | Master of Philosophy (Clinical Science) | Master | Full Time | Dr Alessandra Pina |
| 2024 | Co-Supervisor | PREDICTive value of aggressive risk factor modification on the occurrence of major cardiovascular events in patients with embolic STROKE (PREDICT-STROKE) | Doctor of Philosophy | Doctorate | Full Time | Dr Elnaz Shahmohamadi |
| 2024 | Co-Supervisor | Redesigning care with an Emergency Department protocol and rapid access clinic to reduce hospitalisations for Atrial Fibrillation (REDUCE-AF) | - | Master | Full Time | Dr Alessandra Pina |
| 2023 | Co-Supervisor | Efficacy of personalised exercise for the reduction of cardiovascular risk and primary prevention of cardiovascular disease | Doctor of Philosophy | Doctorate | Full Time | Mrs Jenelle Kay Dziano |
| 2023 | Co-Supervisor | The effects of exercise-based rehabilitation on atrial fibrillation recurrence following catheter ablation | Doctor of Philosophy | Doctorate | Full Time | Mr Jackson Oliver Howie |
| 2023 | Co-Supervisor | Advances in diagnostic and therapeutic cardiology provided by big data and machine learning | Doctor of Philosophy | Doctorate | Full Time | Shaun Christopher Evans |
| 2023 | Co-Supervisor | Predict Stroke - Will closer/proper risk factor management in patients with previous stroke prevents them from getting another stroke? | Doctor of Philosophy | Doctorate | Full Time | Mr Mohanaraj Jayakumar |
| 2023 | Co-Supervisor | Approaches to monitoring and management of cardiac arrhythmias | Doctor of Philosophy | Doctorate | Full Time | Dr Suraya Hani Binti Kamsani |
| 2023 | Co-Supervisor | Approaches to monitoring and management of cardiac arrhythmias | Doctor of Philosophy | Doctorate | Full Time | Dr Suraya Hani Binti Kamsani |
| 2023 | Co-Supervisor | Efficacy of personalised exercise for the reduction of cardiovascular risk and primary prevention of cardiovascular disease | Doctor of Philosophy | Doctorate | Full Time | Mrs Jenelle Kay Dziano |
| 2023 | Co-Supervisor | Advances in diagnostic and therapeutic cardiology provided by big data and machine learning | Doctor of Philosophy | Doctorate | Full Time | Shaun Christopher Evans |
| 2023 | Co-Supervisor | The effects of exercise-based rehabilitation on atrial fibrillation recurrence following catheter ablation | Doctor of Philosophy | Doctorate | Full Time | Mr Jackson Oliver Howie |
| 2023 | Co-Supervisor | Predict Stroke - Will closer/proper risk factor management in patients with previous stroke prevents them from getting another stroke? | Doctor of Philosophy | Doctorate | Full Time | Mr Mohanaraj Jayakumar |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2019 - 2023 | Co-Supervisor | Screening, risk stratification, and management of atrial fibrillation | Doctor of Philosophy | Doctorate | Full Time | Dr Jean Jacques Noubiap Nzeale |
| 2019 - 2024 | Co-Supervisor | Remote Monitoring of Cardiac Implantable Electronic Devices: Characterisation of Clinical Burden, Use in Arrhythmia Detection and Impact on Patient Outcomes | Doctor of Philosophy | Doctorate | Full Time | Dr Catherine O'shea |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2020 - 2020 | Principal Supervisor | Population screening for atrial fibrillation and stroke risk using eHealth technology | Universty of Adelaide | MBBS | Other | - | Sharadi Wijesinghe |
| 2020 - 2020 | Principal Supervisor | Population screening for atrial fibrillation and stroke risk using eHealth technology | Universty of Adelaide | MBBS | Other | - | Phoebe Chao |
| 2020 - 2020 | Principal Supervisor | Population screening for atrial fibrillation and stroke risk using eHealth technology | Universty of Adelaide | MBBS | Other | - | Samiksha Mali |
| 2020 - 2020 | Principal Supervisor | Population screening for atrial fibrillation and stroke risk using eHealth technology | Universty of Adelaide | MBBS | Other | - | Xin Lee |
| 2019 - 2019 | Principal Supervisor | Impact of Lipids on AF Development | University of Adelaide | MBBS | Other | - | Tri Nguyen |
| 2019 - 2019 | Principal Supervisor | Impact of Lipids on AF developement | University of Adelaide | MBBS | Other | - | Gabriel Lapaglia |
| 2019 - 2019 | Principal Supervisor | Impact of Lipids on AF Development | University of Adelaide | MBBS | Other | - | Tanishq Mathur |
| 2019 - 2019 | Principal Supervisor | Impact of Lipids on AF Development | University of Adelaide | MBBS | Other | - | Thisun Gange |
| 2019 - 2019 | Principal Supervisor | Role of Yoga in Atrial Fibrillation | University of Adelaide | MBBS | Other | - | Ayra Perakath |
| 2019 - 2019 | Principal Supervisor | Role of Yoga and Atrial Fibrillation | University of Adelaide | MBBS | Other | - | Elena Te |
| 2019 - 2019 | Principal Supervisor | Role of Yoga and Atrial Fibrillation | University of Adelaide | MBBS | Other | - | Meg Schulz |
| 2019 - 2019 | Principal Supervisor | Role of Yoga and Atrial Fibrillation | University of Adelaide | MBBS | Other | - | Shyanne Premnath |
| Date | Topic | Location | Name |
|---|---|---|---|
| 2021 - 2021 | Honours: Impact of intensive follow-up of cardiac implantable electronic devices via remote monitoring: a pilot study | University of Adelaide | Kyle Heath |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2024 - ongoing | Member | CSANZ Heart Rhythm Council | Cardiac Society of Australia and New Zealand | Australia |
| 2024 - ongoing | Member | Heart Rhythm Society Digital Education Committee | Heart Rhythm Society | United States |
| 2024 - ongoing | Member | Heart Rhythm Society Allied Professional Council | Heart Rhythm Society | United States |
| 2023 - ongoing | Board Member | Asia Pacific Heart Rhythm Society Program Comittee | Asia Pacific Heart Rhythm Society | Australia |
| 2023 - ongoing | Member | Heart Rhythm Society Quality Improvement Committee | Heart Rhythm Society | United States |
| 2020 - ongoing | Member | Heart Rhythm Society Leadership and Education in Allied Professional Program | Heart Rhythm Society | United States |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2019 - ongoing | Member | American Heart Association | United States |
| 2018 - ongoing | Member | European Heart Rhythm Association | France |
| 2017 - ongoing | Member | Asia Pacific Heart Rhythm Society | Singapore |
| 2017 - ongoing | Member | European Society of Cardiology | France |
| 2015 - ongoing | Member | Heart Rhythm Society | United States |
| Date | Engagement Type | Partner Name |
|---|---|---|
| 2021 - ongoing | Consultant | Fibricheck |
| 2019 - ongoing | Consultant | Pacemate |
| Date | Title | Type | Institution | Country |
|---|---|---|---|---|
| 2025 - ongoing | Abstract Grading: European Society of Cardiology 2025 | Peer Review | European Society of Cardiology | - |
| 2024 - ongoing | Abstract Grader: Heart Rhythm Society 2025 | Peer Review | Heart Rhythm Society | - |
| 2024 - ongoing | Abstract Grader: Asia Pacific Heart Rhythm Society 2024 | Peer Review | Asia Pacific Heart Rhythm Society | - |
| 2024 - ongoing | Abstract Grading: European Society of Cardiology 2024 | Peer Review | European Society of Cardiology | - |
| 2024 - ongoing | Abstract Grading: Heart Rhythm Society 2024 | Peer Review | Heart Rhythm Society | - |
| 2023 - ongoing | Abstract Grading: Annual Scientific of the Heart Rhythm Society 2023 | Peer Review | Heart Rhythm Society | - |
| 2022 - ongoing | Abstract Grading: Annual Scientific of the Heart Rhythm Society 2022 | Peer Review | Heart Rhythm Society | - |
| 2021 - ongoing | Abstract Grading: Annual Scientific of the Heart Rhythm Society 2021 | Peer Review | Heart Rhythm Society | - |
| 2020 - ongoing | Clinical Medicine Insights: Cardiology | Journal Review | Clinical Medicine Insights: Cardiology | - |
| 2020 - ongoing | PLOS ONE | Journal Review | PLOS ONE | - |
| 2020 - ongoing | European Heart Journal | Journal Review | European Heart Journal | - |
| 2020 - ongoing | The American Journal of Cardiology | Journal Review | The American Journal of Cardiology | - |
| 2020 - ongoing | International Journal of Cardiology-Heart and Vasculature | Journal Review | International Journal of Cardiology-Heart and Vasculature | - |
| 2020 - ongoing | Expert Review of Medical Devices | Journal Review | Expert Review of Medical Devices | - |
| 2020 - ongoing | BMC Medicine | Journal Review | BMC Medicine | - |
| 2020 - ongoing | Abstract Grading: Annual Scientific of the Heart Rhythm Society 2020 | Peer Review | Heart Rhythm Society | - |
| 2019 - ongoing | Clinical Cardiology | Journal Review | Clinical Cardiology | - |
| 2019 - ongoing | Journal of Cardiovascular Electrophysiology | Journal Review | Journal of Cardiovascular Electrophysiology | United States |
| 2019 - ongoing | Journal of the American College of Cardiology | Peer Review | American College of Cardiology | United States |
| 2019 - ongoing | The American Heart Journal | Peer Review | American Heart | United States |
| 2019 - ongoing | Pacing and Clinical Electrophysiology | Peer Review | PACE | United States |
| 2018 - ongoing | Journal of Interventional Cardiac Electrophysiology | Peer Review | ECAS | United States |