Dr Stephen Kidd

Stephen Kidd
Microbiology & Immunology Senior Lecturer
School of Biological Sciences
Faculty of Sciences

Stephen graduated from the University of Queensland (PhD - molecular microbiology) and then undertook postdoctoral work at the University of Birmingham (UK) with Prof Nigel Brown. He moved to the University of Adelaide in 2008 where he works on pathogenic bacteria. He has consistently worked on gene regulation in bacteria.

His current research is focussed on determining the molecular and transcriptional systems bacteria use to survive under prolonged periods of time with stress. What is particularly interesting is that within an anatomical niche and importantly, over time, bacteria generate a diversity of cell types and these enable survival. Identifying and characterising these adaptive cell types is important for understanding chronic and relapsing infectious diseases. His research investigates various pathogenic bacteria. Within different anatomical niches he is interested in numerous stresses the bacteria encounter and these include nutrient stress, changes in pH as well a direct chemical stress (such as oxidative stress) and the stress generated by antibiotics.

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Dr Stephen Kidd

Stephen graduated from the University of Queensland (PhD - molecular microbiology) and then undertook postdoctoral work at the University of Birmingham (UK) with Prof Nigel Brown. He moved to the University of Adelaide in 2008 where he works on pathogenic bacteria. He has consistently worked on gene regulation in bacteria.

His current research is focussed on determining the molecular and transcriptional systems bacteria use to survive under prolonged periods of time with stress. What is particularly interesting is that within an anatomical niche and importantly, over time, bacteria generate a diversity of cell types and these enable survival. Identifying and characterising these adaptive cell types is important for understanding chronic and relapsing infectious diseases. His research investigates various pathogenic bacteria. Within different anatomical niches he is interested in numerous stresses the bacteria encounter and these include nutrient stress, changes in pH as well a direct chemical stress (such as oxidative stress) and the stress generated by antibiotics.

Appointments

Date Position Institution name
2013 Senior Lecturer University of Adelaide
2008 - 2012 Lecturer University of Adelaide

Awards and Achievements

Date Type Title Institution Name Amount
2012 Faculty of Science Early Career Teaching Award University of Adelaide
2009 Fellow of the Australian Society for Microbiology ASM

Education

Date Institution name Country Title
1995 - 1998 University of Queensland Australia PhD

Keywords

Infectious Diseases, Medical Microbiology, Microbiology

Journals

Date Citation
2017 Bui,L, Conlon,B, Kidd,S, 2017, Antibiotic tolerance and the alternative lifestyles of Staphylococcus aureus, Essays in Biochemistry, 61, 1, 71-79 10.1042/EBC20160061
2017 Zilm,P, Butnejski,V, Rossi-Fedele,G, Kidd,S, Edwards,S, Vasilev,K, 2017, D-Amino acids reduce Enterococcus faecalis biofilms in vitro and in the presence of antimicrobials used for root canal treatment, PLoS ONE, 12, 2, - 10.1371/journal.pone.0170670
2016 Jiang,D, Tikhomirova,A, Bent,S, Kidd,S, 2016, A discrete role for FNR in the transcriptional response to moderate changes in oxygen by Haemophilus influenzae Rd KW20, Research in Microbiology, 167, 2, 103-113 10.1016/j.resmic.2015.09.008
2016 Ou,J, Drilling,A, Cooksley,C, Bassiouni,A, Kidd,S, Psaltis,A, Wormald,P, Vreugde,S, 2016, Reduced innate immune response to a Staphylococcus aureus small colony variant compared to its wild-type parent strain, Frontiers in Cellular and Infection Microbiology, 6, DEC, 1-9 10.3389/fcimb.2016.00187
2016 Jiang,D, Tikhomirova,A, Kidd,S, 2016, Haemophilus influenzae strains possess variations in the global transcriptional profile in response to oxygen levels and this influences sensitivity to environmental stresses, Research in Microbiology, 167, 1, 13-19 10.1016/j.resmic.2015.08.004
2015 Tikhomirova,A, Trappetti,C, Paton,J, Kidd,S, 2015, The outcome of H. influenzae and S. pneumoniae inter-species interactions depends on pH, nutrient availability and growth phase, International Journal of Medical Microbiology, 305, 8, 881-892 10.1016/j.ijmm.2015.09.003
2015 Bui,L, Kidd,S, 2015, A full genomic characterization of the development of a stable Small Colony Variant cell-type by a clinical Staphylococcus aureus strain, Infection, Genetics and Evolution, 36, 345-355 10.1016/j.meegid.2015.10.011
2015 Bui,L, Hoffmann,P, Turnidge,J, Zilm,P, Kidd,S, 2015, Prolonged growth of a clinical Staphylococcus aureus strain selects for a stable small-colony-variant cell type, Infection and Immunity, 83, 2, 470-481 10.1128/IAI.02702-14
2015 Tikhomirova,A, Jiang,D, Kidd,S, 2015, A new insight into the role of intracellular nickel levels for the stress response, surface properties and twitching motility by Haemophilus influenzae, Metallomics, 7, 4, 650-661 10.1039/c4mt00245h
2015 Bui,L, Turnidge,J, Kidd,S, 2015, The induction of Staphylococcus aureus biofilm formation or Small Colony Variants is a strain-specific response to host-generated chemical stresses, Microbes and Infection, 17, 1, 77-82 10.1016/j.micinf.2014.09.009
2014 Ishak,N, Tikhomirova,A, Bent,SJ, Ehrlich,GD, Hu,FZ, Kidd,SP, 2014, There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation, BMC Microbiology, 14, 1, 1-10 10.1186/1471-2180-14-47
2013 Tikhomirova,A, Kidd,S, 2013, Haemophilus influenzae and Streptococcus pneumoniae: living together in a biofilm, Pathogens and Disease, 69, 2, 114-126 10.1111/2049-632X.12073
2013 Ng,J, Kidd,S, 2013, The concentration of intracellular nickel in Haemophilus influenzae is linked to its surface properties and cell-cell aggregation and biofilm formation, International Journal of Medical Microbiology, 303, 3, 150-157 10.1016/j.ijmm.2013.02.012
2012 Djoko,K, Franiek,J, Edwards,J, Falsetta,M, Kidd,S, Potter,A, Chen,N, Apicella,M, Jennings,M, McEwan,A et al, 2012, Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress, Infection and Immunity, 80, 3, 1065-1071 10.1128/IAI.06163-11
2012 Kidd,S, Jiang,C, Tikhomirova,A, Jennings,M, McEwan,A, 2012, A glutathione-based system for defense against carbonyl stress in Haemophilus influenzae, BMC Microbiology, 12, 1, 1-6 10.1186/1471-2180-12-159
2011 Kidd,SP, 2011, Advances in molecular and cellular microbiology: Stress response in pathogenic bacteria, Advances in Molecular and Cellular Microbiology: Stress Response in Pathogenic Bacteria, 1-306
2011 Kidd,S, Djoko,K, Ng,J, Argente,M, Jennings,M, McEwan,A, 2011, A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae, Metallomics; integrated biometals science, 3, 10, 1009-1018 10.1039/c1mt00127b
2011 McEwan,A, Djoko,K, Chen,N, Counago,R, Kidd,S, Potter,A, Jennings,M, 2011, Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress, Advances in Microbial Physiology, 58, 1-22 10.1016/B978-0-12-381043-4.00001-5
2010 Potter,A, Kidd,S, McEwan,A, Paton,J, 2010, The MerR/NmlR Family Transcription Factor of Streptococcus pneumoniae responds to carbonyl stress and modulates hydrogen peroxide production, Journal of Bacteriology, 192, 15, 4063-4066 10.1128/JB.00383-10
2010 Pidot,S, Porter,J, Tobias,N, Anderson,J, Catmull,D, Seemann,T, Kidd,S, Davies,J, Reynolds,E, Dashper,S et al, 2010, Regulation of the 18 kDa heat shock protein in Mycobacterium ulcerans: An alpha-crystallin orthologue that promotes biofilm formation, Molecular Microbiology, 78, 5, 1216-1231 10.1111/j.1365-2958.2010.07401.x
2010 Wu,H, Seib,K, Srikhanta,Y, Edwards,J, Kidd,SP, Maguire,TL, Hamilton,A, Pan,KT, Hsiao,HH, Yao,CW et al, 2010, Manganese regulation of virulence factors and oxidative stress resistance in Neisseria gonorrhoeae, Journal of Proteomics, 73, 5, 899-916 10.1016/j.jprot.2009.12.001
2009 Potter,A, Kidd,S, Edwards,J, Falsetta,M, Apicella,M, Jennings,M, McEwan,A, 2009, Thioredoxin reductase is essential for protection of neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells, Journal of Infectious Diseases, 199, 2, 227-235 10.1086/595737
2009 Potter,AJ, Kidd,SP, Edwards,JL, Falsetta,ML, Apicella,MA, Jennings,MP, McEwan,AG, 2009, Esterase D is essential for protection of neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells, The Journal of Infectious Diseases, 200, 2, 273-278 10.1086/599987
2007 Potter,A, Kidd,S, Jennings,M, McEwan,A, 2007, Evidence for distinctive mechanisms of S-nitrosoglutathione metabolism by AdhC in two closely related species, Neisseria gonorrhoeae and Neisseria meningitidis, Infection and Immunity, 75, 3, 1534-1536 10.1128/IAI.01634-06
2007 Stroeher,U, Kidd,S, Stafford,S, Jennings,M, Paton,J, McEwan,A, 2007, A pneumococcal MerR-like regulator and S-nitrosoglutathione reductase are required for systemic virulence, Journal of Infectious Diseases, 196, 12, 1820-1826 10.1086/523107
2007 Kidd,S, Jiang,D, Jennings,M, McEwan,A, 2007, Glutathione-dependent alcohol dehydrogenase AdhC is required for defense against nitrosative stress in Haemophilus influenzae., Infection and Immunity, 75, 9, 4506-4513 10.1128/IAI.00487-07
2006 Seib,K, Wu,HJ, Kidd,S, Apicella,M, Jennings,M, McEwan,A, 2006, Defenses against oxidative stress in Neisseria gonorrhoeae: a system tailored for a challenging environment, Microbiology and Molecular Biology Reviews, 70, 2, 344-361 10.1128/MMBR.00044-05
2006 Wu,HJ, Seib,K, Srikhanta,Y, Kidd,S, Edwards,J, Maguire,T, Grimmond,S, Apicella,M, McEwan,A, Jennings,M et al, 2006, PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae, Molecular Microbiology, 60, 2, 401-416 10.1111/j.1365-2958.2006.05079.x
2005 Kidd,S, Potter,A, Apicella,M, Jennings,M, McEwan,A, 2005, NmlR of Neisseria gonorrhoeae : a novel redox responsive transcription factor from the MerR family, Molecular Microbiology, 57, 6, 1676-1689 10.1111/j.1365-2958.2005.04773.x
2005 Tree,J, Kidd,S, Jennings,M, McEwan,A, 2005, Copper sensitivity of cueO mutants of Escherichia coli K-12 and the biochemical suppression of this phenotype, Biochemical and Biophysical Research Communications, 328, 4, 1205-1210 10.1016/j.bbrc.2005.01.084
2005 Harrison,R, Jones,A, Biggins,P, Pomeroy,N, Cox,C, Kidd,S, Hobman,J, Brown,N, Beswick,A, 2005, Climate factors influencing bacterial count in background air samples, International Journal of Biometeorology, 49, 3, 167-178 10.1007/s00484-004-0225-3
2003 Kidd,S, Brown,N, 2003, ZccR-a MerR-like regulator from Bordetella pertussis which responds to zinc, cadmium, and cobalt, Biochemical and Biophysical Research Communications, 302, 4, 697-702 10.1016/S0006-291X(03)00249-3
2003 Brown,N, Stoyanov,J, Kidd,S, Hobman,J, 2003, The MerR family of transcriptional regulators, FEMS Microbiology Reviews, 27, 2-3, 145-163 10.1016/S0168-6445(03)00051-2
2003 Essa,A, Julian,D, Kidd,S, Brown,N, Hobman,J, 2003, Mercury resistance determinants related to Tn21, Tn1696, and Tn5053 in enterobacteria from the preantibiotic era, Antimicrobial Agents and Chemotherapy, 47, 3, 1115-1119 10.1128/AAC.47.3.1115-1119.2003
2002 Kidd,SP, Pemberton,JM, 2002, The cloning and characterization of a second α-amylase of A. hydrophila JMP636, Journal of Applied Microbiology, 92, 2, 289-296 10.1046/j.1365-2672.2002.01529.x
2002 Kidd,SP, Pemberton,JM, 2002, The identification of the transcriptional regulator CRP in Aeromonas hydrophila JMP636 and its involvement in amylase production and the 'acidic toxicity' effect, Journal of Applied Microbiology, 93, 5, 787-793 10.1046/j.1365-2672.2002.01750.x
1997 Pemberton,JM, Kidd,SP, Schmidt,R, 1997, Secreted enzymes of Aeromonas, FEMS Microbiology Letters, 152, 1, 1-10 10.1111/j.1574-6968.1997.tb10401.x

Book Chapters

Date Citation
2016 Kyd,J, Krishnamurthy,A, Kidd,SP, 2016, Interactions and Mechanisms of Respiratory Tract Biofilms Involving Streptococcus Pneumoniae and Nontypeable Haemophilus Influenzae, InTech, pp. 299-327 10.5772/61499
2011 Kidd,S, 2011, Novel Regulation in Response to Host-generated Stresses: The MerR Family of Regulators in Pathogenic Bacteria, CABI Publishing, United Kingdom, pp. 93-114

Memberships

Date Role Membership Country
2015 Member Australian Society for Antimicrobials Australia
2014 Member American Society for Microbiology United States

Committee Memberships

Date Role Committee Institution Country
2016 Chair South Australian/NT ASM Branch committee Australia
2015 Founder StaphPath 2017 conference Australia
2015 Member School of Biological Sciences Teaching and Learning Committee University of Adelaide Australia
2015 Member Masters of Biotechnology (Biomed. Sciences) Steering Committee University of Adelaide
2012 Member South Australian/NT ASM committee ASM Australia

Editorial Boards

Date Role Editorial Board Name Country
2014 Consulting Editor Frontiers in cellular and infection microbiology

Offices Held

Date Office Name Institution Country
2016 Chair SA/NT branch ASM ASM Australia
Position
Microbiology & Immunology Senior Lecturer
Phone
83135396
Fax
8313 4362
Campus
North Terrace
Building
Molecular Life Sciences
Room Number
5 17
Org Unit
Molecular and Cellular Biology

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