Mr Zhenwei Lan
Higher Degree by Research Candidate
School of Chemical Engineering
College of Engineering and Information Technology
The advanced understanding of diseases underscores the pressing need for precision medicine, where LNP-based mRNA therapy offers considerable promise. Here, I will focus on the development of platform technology for mRNA-LNP adapting to precision medicine, streamlining the transition from diagnostic affirmation to drug availability, and mitigating the influence of factors such as mRNA itself and formula instability on products to a certain extent. Additionally, we will work to devise an integrated functional module to adapt to different source of data input, so that users can easily enter parameters to obtain the target product.
| Language | Competency |
|---|---|
| Chinese (Mandarin) | Can read, write, speak, understand spoken and peer review |
| English | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2019 - 2022 | Guangdong Pharmaceutical University | China | Master of Medicine |
| Year | Citation |
|---|---|
| 2026 | Wang, X., Xu, L., Lan, Z., Hui, Y., Liu, Y., Yang, G., & Zhao, C. X. (2026). Advances in the Development of Lipid Nanoparticles for mRNA Delivery. Small Structures, 7(2), e202500568-1-e202500568-37. Scopus1 |
| 2026 | Xu, L., Lan, Z., Zewail, M. B., Fan, Y., & Zhao, C. X. (2026). Nanoprecipitation-induced formation of nanoparticles for drug delivery. Current Opinion in Colloid and Interface Science, 83, 102014-1-102014-20. Scopus5 WoS4 |
| 2026 | Li, Y., Hui, Y., Wang, J., Guo, Z., Ye, Z., Orchard, M., . . . Zhao, C. -X. (2026). Minimal Peptide Surfactants for Long-Lasting Nanoemulsions via Noncovalent Interfacial Interactions. ACS applied materials & interfaces, 18(17), 25590-25602. |
| 2025 | Lan, Z., Chen, R., Zou, D., & Zhao, C. -X. (2025). Microfluidic Nanoparticle Separation for Precision Medicine. Advanced Science, 12(4), 2411278-1-2411278-38. Scopus56 WoS53 Europe PMC25 |
| 2025 | Lan, Z., Zhang, X., Cai, X., Pan, W., Li, W., Sun, Y., . . . Meng, J. (2025). Metabolite profiling and ‘dryness’-like effect analysis of ‘Chenpi’ plant tea (Citri Reticulatae Pericarpium peel) with and without steaming peocessing. Food Research International, 206, 116089-1-116089-17. Scopus7 WoS7 Europe PMC2 |
| 2024 | Lan, Z., Yang, R., Wang, H., Xue, X., Sun, Y., Wang, S., . . . Meng, J. (2024). Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation. Bioorganic Chemistry, 147, 11 pages. Scopus11 WoS11 Europe PMC5 |
| 2024 | Jin, S., Lan, Z., Yang, G., Li, X., Shi, J. Q., Liu, Y., & Zhao, C. (2024). Computationally guided design and synthesis of dual‐drug loaded polymeric nanoparticles for combination therapy. Aggregate, 5(5), e606-1-e606-10. Scopus15 WoS13 |
| 2024 | Yang, R., Cui, L., Xu, S., Zhong, Y., Xu, T., Liu, J., . . . Guo, Y. (2024). Membrane-Targeting Amphiphilic Honokiol Derivatives Containing an Oxazole Moiety as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus. Journal of Medicinal Chemistry, 67(18), 16858-16872. Scopus36 WoS38 Europe PMC18 |
| 2022 | Lan, Z., Zhang, Y., Lin, H., Sun, Y., Wang, S., & Meng, J. (2022). Efficient monitoring for the nutrient changes in stir-fried Moutan Cortex using non-destructive near-infrared spectroscopy sensors. Microchemical Journal, 183, 9 pages. Scopus2 WoS2 |
| 2022 | Lan, Z., Zhang, Y., Chen, X., Li, S., Cao, H., Wang, S., & Meng, J. (2022). Efficient Detection of Limonoid From Citrus Seeds by Handheld NIR: Compared with Benchtop NIR. Food Analytical Methods, 15(7), 1909-1921. Scopus8 WoS7 |
| 2022 | Li, S., Dong, L., Tang, K., Lan, Z., Liu, R., Wang, Y., . . . Lin, H. (2022). Simultaneous and trace level quantification of two potential genotoxic impurities in valsartan drug substance using UPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 212, 6 pages. Scopus19 WoS15 Europe PMC5 |
| 2021 | Lan, Z., Zhang, Y., Sun, Y., Wang, L., Huang, Y., Cao, H., . . . Meng, J. (2021). Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS. Frontiers in Pharmacology, 12, 16 pages. Scopus16 WoS14 |
| 2021 | Lan, Z., Zhang, Y., Zhang, Y., Liu, F., Ji, D., Cao, H., . . . Meng, J. (2021). Rapid evaluation on pharmacodynamics of Curcumae Rhizoma based on Micro-NIR and benchtop-NIR. Journal of Pharmaceutical and Biomedical Analysis, 200, 10 pages. Scopus19 WoS18 Europe PMC7 |
| 2021 | Lan, Z., Zhang, Y., Sun, Y., Ji, D., Wang, S., Lu, T., . . . Meng, J. (2021). Rapid quantitative detection of the discrepant compounds in differently processed Curcumae Rhizoma products by FT-NIR combined with VCPA-GA technology. Journal of Pharmaceutical and Biomedical Analysis, 195, 10 pages. Scopus21 WoS18 Europe PMC13 |
| 2020 | Lan, Z., Zhang, Y., Sun, Y., Ji, D., Wang, S., Lu, T., . . . Meng, J. (2020). A mid-level data fusion approach for evaluating the internal and external changes determined by FT-NIR, electronic nose and colorimeter in Curcumae Rhizoma processing. Journal of Pharmaceutical and Biomedical Analysis, 188, 11 pages. Scopus54 WoS41 Europe PMC18 |
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