| 2025 |
Shabbar, M., Manning, J., Lim, Y., Shah, S., Sinha, D., Nikolic, A., . . . Kumar, S. (2025). Phospholipid scramblase 1 (PLSCR1) is a novel substrate of NEDD4-2 (NEDD4L) mediated ubiquitination. Cell Death Discovery, 11(1, article no. 393), 1-11. DOI Scopus1 WoS1 |
| 2025 |
Shah, S. S., Manning, J. A., Lim, Y., Sinha, D., Murthy, A. M. V., Ganesan, R., . . . Kumar, S. (2025). NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury.. Cell Death Differ, online, 1-18. DOI |
| 2024 |
Nicolson, S., Manning, J. A., Lim, Y., Jiang, X., Kolze, E., Dayan, S., . . . Denton, D. (2024). The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy. Communications Biology, 7(1), 183-1-183-24. DOI Scopus5 WoS3 Europe PMC4 |
| 2024 |
Dawar, S., Benitez, M. C., Lim, Y., Dite, T. A., Yousef, J. M., Thio, N., . . . Clemons, N. J. (2024). Caspase-2 protects against ferroptotic cell death. Cell Death and Disease, 15(3), 182-1-182-12. DOI Scopus13 WoS12 Europe PMC11 |
| 2024 |
Vora, S., Andrew, A., Kumar, R. P., Nazareth, D., Bonfim-Melo, A., Lim, Y., . . . Gabrielli, B. (2024). Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition. Cell Death and Disease, 15(11, article no. 810), 810-1-810-9. DOI Scopus6 WoS6 Europe PMC4 |
| 2022 |
Kumar, S., Dorstyn, L., & Lim, Y. (2022). The role of caspases as executioners of apoptosis. Biochemical Society Transactions, 50(1), 33-45. DOI Scopus46 WoS42 Europe PMC37 |
| 2022 |
Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689. DOI Scopus17 WoS17 Europe PMC17 |
| 2022 |
Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756. DOI |
| 2021 |
Lim, Y., De Bellis, D., Sandow, J. J., Capalbo, L., D'Avino, P. P., Murphy, J. M., . . . Kumar, S. (2021). Phosphorylation by Aurora B kinase regulates caspase-2 activity and function.. Cell Death and Differentiation, 28(1), 349-366. DOI Scopus25 WoS24 Europe PMC24 |
| 2021 |
Lim, Y., Dorstyn, L., & Kumar, S. (2021). The p53-caspase-2 axis in the cell cycle and DNA damage response. Experimental and Molecular Medicine, 53(4), 517-527. DOI Scopus44 WoS40 Europe PMC36 |
| 2020 |
Li, H., Lin, L. Y., Zhang, Y., Lim, Y., Rahman, M., Beck, A., . . . Zhou, X. F. (2020). Pro-BDNF knockout causes abnormal motor behaviours and early death in mice. Neuroscience, 438, 145-157. DOI Scopus14 WoS12 Europe PMC10 |
| 2019 |
Dorstyn, L., Hackett-Jones, E., Nikolic, A., Norris, M. D., Lim, Y., Toubia, J., . . . Kumar, S. (2019). Transcriptome profiling of caspase-2 deficient EµMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling. Cell Death and Disease, 10(2), 56-1-56-16. DOI Scopus7 WoS6 Europe PMC6 |
| 2018 |
Saadipour, K., Mañucat-Tan, N. B., Lim, Y., Keating, D. J., Smith, K. S., Zhong, J. H., . . . Zhou, X. F. (2018). p75 neurotrophin receptor interacts with and promotes BACE1 localization in endosomes aggravating amyloidogenesis. Journal of Neurochemistry, 144(3), 302-317. DOI Scopus28 WoS26 Europe PMC27 |
| 2018 |
Lim, Y., Wu, L., Chen, S., Sun, Y., Vijayaraj, S., Yang, M., . . . Zhou, X. (2018). HAP1 is required for endocytosis and signalling of BDNF and its receptors in neurons. Molecular Neurobiology, 55(3), 1815-1830. DOI Scopus26 WoS23 Europe PMC21 |
| 2018 |
Lim, Y., De Bellis, D., Dorstyn, L., & Kumar, S. (2018). p53 accumulation following cytokinesis failure in the absence of caspase-2. Cell Death and Differentiation, 25(11), 2050-2052. DOI Scopus11 WoS10 Europe PMC10 |
| 2017 |
Dawar, S., Lim, Y., Puccini, J., White, M., Thomas, P., Bouchier-Hayes, L., . . . Kumar, S. (2017). Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene, 36(19), 2704-2714. DOI Scopus55 WoS52 Europe PMC50 |
| 2017 |
Lim, Y. Y., Rainey-Smith, S., Lim, Y., Laws, S. M., Gupta, V., Porter, T., . . . Maruff, P. (2017). BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF. International Psychogeriatrics, 29(11), 1825-1834. DOI Scopus22 WoS18 Europe PMC18 |
| 2017 |
Mackenzie, K. D., Lim, Y., Duffield, M. D., Chataway, T., Zhou, X. F., & Keating, D. J. (2017). Huntingtin-associated protein-1 (HAP1) regulates endocytosis and interacts with multiple trafficking-related proteins. Cellular Signalling, 35, 176-187. DOI Scopus30 WoS29 Europe PMC26 |
| 2016 |
Mackenzie, K. D., Lumsden, A. L., Guo, F., Duffield, M. D., Chataway, T., Lim, Y., . . . Keating, D. J. (2016). Huntingtin-associated protein-1 is a synapsin I-binding protein regulating synaptic vesicle exocytosis and synapsin I trafficking. Journal of Neurochemistry, 138(5), 710-721. DOI Scopus22 WoS22 Europe PMC21 |
| 2016 |
Han, Y. C., Lim, Y., Duffieldl, M. D., Li, H., Liu, J., Abdul Manaph, N. P., . . . Zhou, X. F. (2016). Direct reprogramming of mouse fibroblasts to neural stem cells by small molecules. Stem Cells International, 2016(4304916), 4304916-1-4304916-11. DOI Scopus51 WoS49 Europe PMC43 |
| 2015 |
Xiong, J., Zhou, L., Lim, Y., Yang, M., Zhu, Y., Wei Li, Z., . . . Zhou, X. (2015). Mature brain-derived neurotrophic factor and its receptor TrkB are upregulated in human glioma tissues. Oncology Letters, 10(1), 223-227. DOI Scopus32 WoS33 Europe PMC28 |
| 2015 |
Lim, Y., & Kumar, S. (2015). A single cut to pyroptosis. Oncotarget, 6(35), 36926-36927. DOI Scopus25 WoS21 Europe PMC18 |
| 2015 |
Johnson, M. E., Lim, Y., Senthilkumaran, M., Zhou, X. F., & Bobrovskaya, L. (2015). Investigation of tyrosine hydroxylase and BDNF in a low-dose rotenone model of Parkinson's disease. Journal of Chemical Neuroanatomy, 70, 33-41. DOI Scopus31 WoS27 Europe PMC23 |
| 2015 |
Lim, Y., Zhong, J. H., & Zhou, X. F. (2015). Development of mature BDNF-specific sandwich ELISA. Journal of Neurochemistry, 134(1), 75-85. DOI Scopus49 WoS46 Europe PMC43 |
| 2013 |
Xiong, J., Zhou, L., Yang, M., Lim, Y., Zhu, Y., Fu, D., . . . Zhou, X. (2013). ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro. Neuro-Oncology, 15(8), 990-1007. DOI Scopus63 WoS55 Europe PMC49 |
| 2013 |
Xiong, J., Zhou, L., Lim, Y., Yang, M., Zhu, Y., Li, Z., . . . Zhou, X. (2013). Mature BDNF promotes the growth of glioma cells in vitro. Oncology Reports, 30(6), 2719-2724. DOI Scopus43 WoS38 Europe PMC35 |
| 2013 |
Zhou, L., Xiong, J., Lim, Y., Ruan, Y., Huang, C., Zhu, Y., . . . Zhou, X. F. (2013). Upregulation of blood proBDNF and its receptors in major depression. Journal of Affective Disorders, 150(3), 776-784. DOI Scopus131 WoS121 Europe PMC107 |
| 2013 |
Saadipour, K., Yang, M., Lim, Y., Georgiou, K., Sun, Y., Keating, D., . . . Zhou, X. (2013). Amyloid beta₁–-₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway. Journal of Neurochemistry, 127(2), 152-162. DOI Scopus47 WoS42 Europe PMC40 |
| 2013 |
Yang, M., Virassamy, B., Vijayaraj, S., Lim, Y., Saadipour, K., Wang, Y., . . . Zhou, X. (2013). The intracellular domain of sortilin interacts with Amyloid precursor protein and regulates its lysosomal and lipid raft trafficking. PLoS One, 8(5), e63049-1-e63049-13. DOI Scopus30 WoS28 Europe PMC28 |
| 2012 |
Yang, G., Yang, M., Lim, Y., Lu, J., Wang, T., Qi, J., . . . Zhou, X. (2012). Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons. Journal of Neurochemistry, 122(5), 1010-1022. DOI Scopus33 WoS33 Europe PMC28 |
| 2012 |
Sun, Y., Lim, Y., Li, F., Liu, S., Lu, J. J., Haberberger, R., . . . Zhou, X. F. (2012). ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA. PLoS ONE, 7(4), 1-12. DOI Scopus133 WoS95 Europe PMC111 |
| 2011 |
Xu, Z. Q., Sun, Y., Li, H. Y., Lim, Y., Zhong, J. H., & Zhou, X. F. (2011). Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice. European journal of neuroscience, 33(8), 1376-1384. DOI Scopus57 WoS53 Europe PMC47 |
| 2011 |
Yang, M., Lim, Y., Li, X., Zhong, J., & Zhou, X. (2011). Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing. Journal of Biological Chemistry, 286(18), 16272-16284. DOI Scopus67 WoS60 Europe PMC56 |
| 2011 |
Wang, Y., Wang, X., Lu, J., Li, Q., Gao, C., Liu, X., . . . Zhou, X. (2011). p75NTR regulates Aβ deposition by increasing Aβ production but inhibiting Aβ aggregation with its extracellular domain. Journal of Neuroscience, 31(6), 2292-2304. DOI Scopus89 WoS82 Europe PMC75 |
| 2011 |
Wang, Y. J., Valadares, D., Sun, Y., Wang, X., Zhong, J. H., Liu, X. H., . . . Zhou, X. F. (2011). Erratum: Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism (Neurotoxicity Research (2010) 17 (257-267) DOI: 10.1007/s12640-009-9098-x). Neurotoxicity Research, 20(4), 402. DOI WoS1 |
| 2010 |
WANG, Y., Valadares, D., Sun, Y., Wang, X., Zhong, J., Liu, X. H., . . . Zhou, X. F. (2010). Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism. Neurotoxicity research, 17(3), 257-267. DOI Scopus35 WoS34 Europe PMC27 |