Ying Ying Wong

Dr Ying Ying Wong

Grant-Funded Researcher (A)

School of Biomedicine

Faculty of Health and Medical Sciences

No information available as at 19/3/2018.

I am currently undertaking post-doctoral research that focuses on the identification of genetic and epigenetic changes that contribute to Type 1 Diabetes (T1D). T1D results from immune cell-mediated destruction of insulin-producing pancreatic beta cells. The reason a child develops T1D is poorly understood but appears to depend on a complex interaction of genetic predisposition and environmental factors, leading to a breakdown in tolerance normally maintained by Regulatory T (Treg) cells.

My research aims to identify alterations in chromatin accessibility and transcriptome in T cells from T1D patients. Incorporation of chromatin conformation capture contact maps allows us to connect dysregulated non-coding, regulatory enhancers to their long-range target genes. A key aspect of this research is the longitudinal nature of the sample collection so that genetic and epigenetic alterations causing immune dysregulation can be identified prior to the loss of pancreatic beta-cells for the development of interventions that prevent T1D occurrence. 

  • Appointments

    Date Position Institution name
    2022 - ongoing Grant-funded researcher University of Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2022 Award Dean’s Commendation for Doctoral Thesis Excellence University of Adelaide Australia
    2022 Award JDRF Career Support and Travel Grant JDRF Australia
    2021 Award The Australasian Society for Immunology Bursary Australian and New Zealand Society for Immunology Australia
    2019 Award Hans-Jürgen & Marianne Ohff Research Grant University of Adelaide Australia
    2019 Award Robinson Research Institute Travel Grants University of Adelaide Australia
    2018 Award Adelaide Medical School Research Travel Awards University of Adelaide Australia
    2017 Scholarship ENDIA Study Supplementary Scholarship ENDIA/University of Adelaide Australia
    2017 Scholarship Adelaide Graduate Research Scholarships University of Adelaide Australia
    2014 Scholarship Adelaide International Undergraduate Scholarships University of Adelaide Australia
  • Education

    Date Institution name Country Title
    2017 - 2021 University of Adelaide Australia Doctor of Philosophy
    2014 - 2016 University of Adelaide Australia Bachelor of Science (Honours)
    2010 - 2013 Singapore Polytechnic Singapore Diploma in Biomedical Science (Medical Technology)
  • Research Interests

2021-2023 Using 3D genomics to functionally connect genetic risk of Type 1 diabetes to the genes that drive loss of immune tolerance, Juvenile Diabetes Research Foundation Australia.

2021-2022 Connecting the genetic risk of T1D to the genes that are altered by it in immune cells, Diabetes Australia Research Trust.

  • Position: Grant-Funded Researcher (A)
  • Email: yingying.wong@adelaide.edu.au
  • Campus: Womens and Childrens Hospital
  • Building: WCH - Clarence Rieger, floor 2
  • Org Unit: Medical Sciences

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