Research Interests
Biomaterials Biomedical Engineering Tumour Immunology Nanobiotechnology Immunology and InfectionDr Yannan Yang
Group Leader
SAIGENCI
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Yannan Yang completed PhD (Biomedical Engineering) in Australian Institute of Bioengineering and Nanotechnology/University of Queensland in 2019 before taking a postdoctoral research follow position in the same institute. In 2023, he established his own research group (Biomaterials and Immune Engineering Laboratory - BIEL) in SAiGENCI in the University of Adelaide. He has developed innovative synthetic approaches for biomaterials and nanoparticles with controllable architecture and composition, and demonstrated the great potential of materials based cancer immunotherapy. Dr Yang's vision is to develop novel biomaterials-enabled vaccine technology for cancer immunotherapy and promote the clinic translation of the technology to significantly improve the treatment outcome of cancers with poor prognosis.
Dr Yannan Yang is the head of Biomaterials and Immune Engineering Laboratory (BIEL). BIEL aims to leverage state-of-the-art biomaterials and nanotechnology-based approaches to modulate immune system and create translational immunotherapy strategies with improved therapeutic efficacy and minimized adverse effects. Our laboratory is specifically interested in designing and fabricating biocompatible nanoparticles, hydrogels, scaffolds and cell/bacteria derived biomimetic materials with immunomodulatory activities and controlled drug release profile for engineering immunity. We stand at the materials-bio interface and investigate how biomaterials at different scales (nano, micro and bulk) can interact with bio-systems and tumour microenvironment, and how these interactions can be further controlled to benefit the outcome of immunotherapy that aims to prevent and treat cancer.
| Date | Position | Institution name |
|---|---|---|
| 2023 - ongoing | Group Leader | University of Adelaide |
| 2022 - 2023 | NHMRC Emerging Leadership Fellow | University of Queensland |
| 2019 - 2021 | Postdoctoral research fellow | University of Queensland |
| Date | Institution name | Country | Title |
|---|---|---|---|
| University of Queensland | Australia | PhD | |
| University of Queensland | Australia | MPhil | |
| Wuhan University | China | Bachelor |
| Year | Citation |
|---|---|
| 2026 | Dai, Z., Wang, Q., Zhang, M., Shi, Y., Yang, Y., Song, H., . . . Yu, C. (2026). Tumor-activated nanocomplex reprograms cancer and macrophage metabolism in opposite directions to overcome immune suppression. Biomaterials, 326, 12 pages. |
| 2026 | Zou, J., Meng, G., Huang, Y., Huo, J., Yuan, H., Ma, H., . . . Yang, Y. (2026). An intermediate-crystalline phase manganese nanoadjuvant potently activates cGAS-STING signaling and antitumor immunity via immunometabolism normalization. BIOMATERIALS, 328, 17 pages. |
| 2025 | Luo, J., Wang, Y., Yu, C., & Yang, Y. (2025). Bimetallic nanoadjuvants for cancer vaccines.. Trends Pharmacol Sci, 46(10), 958-974. |
| 2025 | Wu, W., Guo, F., Wang, C., Qu, X., Wang, Q., Yang, Y., . . . Ma, Y. (2025). Biomimetic “Trojan Horse” nanoparticles with biotactic behavior toward tumor-associated bacteria for targeted therapy of colorectal cancer. Cell Biomaterials, 1(6), 100092. Scopus2 |
| 2025 | Gong, Y., Zhang, H., Lu, M., Sun, J., Jia, Y., Yang, Y., . . . Ling, Y. (2025). Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications. Journal of Colloid and Interface Science, 679(Pt B), 412-421. Scopus5 WoS6 Europe PMC1 |
| 2025 | Luo, D., Wu, T., Qiu, T., Li, J., Gong, Y., Weng, J., . . . Zhou, Y. (2025). Coordination-Dissociation Induced T<inf>1</inf>-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring. Advanced Functional Materials, 35(33). Scopus3 |
| 2025 | Wu, T., Chen, Y., Gong, Y., Lu, M., Yang, C., Yang, Y., . . . Zhou, Y. (2025). A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells. Molecules, 30(11), 17 pages. |
| 2025 | Shi, Y., Hou, Y., Mabrouk, M. T., Yu, C., & Yang, Y. (2025). In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation. Advanced Science, 12(37), 23 pages. Scopus1 WoS2 Europe PMC1 |
| 2025 | Liu, X., Wang, W., Wu, T., Li, J., Gong, Y., Luo, D., . . . Yang, Y. (2025). Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy. ACS Applied Materials & Interfaces, 17(36), 50548-50559. |
| 2025 | Luo, J., Wang, Y., Dai, Z., Shi, Y., Wu, W., Qu, J., . . . Yang, Y. (2025). Passivation-Engineered Zinc Peroxide Nanoparticles as Th1-Biased Adjuvant for Antitumor Immunity. Small, 21(42), e05250-1-e05250-14. |
| 2024 | Zhang, Y., Yu, Y., Yang, Y., Wang, Y., & Yu, C. (2024). Engineered Silica Nanoparticles for Nucleic Acid Delivery. Small Methods, 8(3), 2300812-1-2300812-16. Scopus8 WoS5 Europe PMC5 |
| 2024 | Yang, Y., Chen, S., Zhang, M., Shi, Y., Luo, J., Huang, Y., . . . Yu, C. (2024). Mesoporous nanoperforators as membranolytic agents via nano- and molecular-scale multi-patterning.. Nat Commun, 15(1), 1891. Scopus2 WoS2 Europe PMC2 |
| 2024 | Zhang, M., Lu, M., Gong, Y., Yang, Y., Song, J., Li, J., . . . Zhou, Y. (2024). Tadpole-Like Carbon Nanotube with Fe Nanoparticle Encapsulated at the Head and Zn Single-Atom Anchored on the Body: One-Pot Carbonization for Tetramodal Synergistic Cancer Therapy. Small, 20(40), e2400587. Scopus3 WoS3 Europe PMC3 |
| 2024 | Huang, Y., Zou, J., Huo, J., Zhang, M., & Yang, Y. (2024). Sulfate Radical Based In Situ Vaccine Boosts Systemic Antitumor Immunity via Concurrent Activation of Necroptosis and STING Pathway. Advanced Materials, 36(41), e2407914-1-e2407914-15. Scopus22 WoS20 Europe PMC12 |
| 2024 | Zhang, Y., Yao, Y., Xie, F., Hu, W. L., Zou, Y., Zhao, Q., . . . Yu, C. (2024). Iron consumption strengthens anti-tumoral STING activation mediated by manganese-based nanoparticles. Nano Today, 58, 102446. Scopus6 WoS6 |
| 2024 | Huo, J., Zou, J., Ma, H., Meng, G., Huang, Y., Yan, X., . . . Zhang, M. (2024). Astragaloside IV microfibers assembling into injectable 3D-scaffolds with intrinsic immunoactivity for enhanced tumor vaccine efficacy. Chemical Engineering Journal, 498, 155511-1-155511-13. Scopus2 WoS1 |
| 2024 | Lu, W., Wang, W., Gong, Y., Li, J., Zhou, Y., & Yang, Y. (2024). A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis.. Small, 20(49), 2407676-1-2407676-12. Scopus7 WoS5 Europe PMC4 |
| 2024 | Jin, Y., Hu, C., Xia, J., Xie, D., Ye, L., Ye, X., . . . Hu, Z. (2024). Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization. Bioactive Materials, 42, 613-627. Scopus9 WoS7 Europe PMC4 |
| 2024 | Li, J., Wu, T., Wang, W., Gong, Y., Lu, M., Zhang, M., . . . Yang, Y. (2024). Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines. Science Advances, 10(38), eadn3002-1-eadn3002-15. Scopus11 WoS6 Europe PMC7 |
| 2023 | Zhang, M., Lu, M., Qiu, T., Wang, Q., Chen, Z., Deng, M., . . . Zhou, Y. (2023). Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications. Small, 19(34), e2301894. Scopus24 Europe PMC9 |
| 2023 | Zhang, M., Huang, Y., Zou, J., Yang, Y., Yao, Y., Cheng, G., & Yang, Y. (2023). Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Advanced Science, 10(22), 10 pages. Scopus15 WoS7 Europe PMC10 |
| 2023 | Li, J., Lu, W., Yang, Y., Xiang, R., Ling, Y., Yu, C., & Zhou, Y. (2023). Hybrid Nanomaterials for Cancer Immunotherapy. Advanced Science, 10(6), 42 pages. Scopus98 WoS94 Europe PMC61 |
| 2023 | Zhang, M., Wu, T., Zhang, H., Chen, Z., Yang, Y., Ling, Y., & Zhou, Y. (2023). Mesoporous carbon hemispheres integrated with Fe-Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy. Journal of Materials Chemistry B, 12(3), 9 pages. Scopus2 WoS3 Europe PMC2 |
| 2023 | Shi, Y., Dai, Z., Wang, Y., Luo, J., Cai, L., Tang, J., . . . Yang, Y. (2023). Engineering Crystallinity Gradients for Tailored CaO₂ Nanostructures: Enabling Alkalinity-Reinforced Anticancer Activity with Minimized Ca²⁺/H₂O₂ Production. Nano letters, 23(23), 10657-10666. Scopus5 WoS5 Europe PMC2 |
| 2022 | Tang, J., Yang, Y., Qu, J., Ban, W., Song, H., Gu, Z., . . . Yu, C. (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13(29), 8507-8517. Scopus22 WoS21 Europe PMC17 |
| 2022 | Wang, F. Y., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie International Edition, 61(41), 12 pages. Scopus10 WoS13 Europe PMC7 |
| 2022 | Theivendran, S., Gu, Z., Tang, J., Yang, Y., Song, H., Yang, Y., . . . Yu, C. (2022). Nanostructured Organosilica Nitric Oxide Donors Intrinsically Regulate Macrophage Polarization with Antitumor Effect. ACS Nano, 16(7), 10943-10957. Scopus70 WoS69 Europe PMC43 |
| 2022 | Yu, Z., Fang, W., Yang, Y., Yao, H., Hu, P., & Shi, J. (2022). Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an Example. Advanced Healthcare Materials, 11(17), 9 pages. Scopus4 WoS4 Europe PMC3 |
| 2022 | Zhang, M., Feng, J., Zhong, Y., Luo, J., Zhao, Y., Yang, Y., . . . Yu, C. (2022). In-situ synthesis of Drug-Containing bactericidal rough silica nanoparticles for antibacterial coating. Chemical Engineering Journal, 440, 1-11. Scopus21 WoS20 |
| 2022 | Wang, F., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie, 134(41). |
| 2022 | Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., . . . Yu, C. (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 1-8. Scopus30 WoS30 Europe PMC14 |
| 2022 | Zhao, L., Zhang, Y., Yang, Y., & Yu, C. (2022). Silica-based Nanoparticles for Enzyme Immobilization and Delivery. Chemistry - An Asian Journal, 17(17), 1-9. Scopus22 WoS22 Europe PMC9 |
| 2022 | Dai, Z., Wang, Q., Tang, J., Qu, R., Wu, M., Li, H., . . . Yu, C. (2022). A Sub-6 nm MnFe<inf>2</inf>O<inf>4</inf>-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy. Biomaterials, 284, 11 pages. Scopus44 WoS42 Europe PMC30 |
| 2022 | Dai, Z., Wang, Q., Tang, J., Wu, M., Li, H., Yang, Y., . . . Yu, C. (2022). Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy. Biomaterials, 280, 121261-1-121261-13. Scopus56 WoS50 Europe PMC38 |
| 2022 | Kothalawala, S. G., Jiao, J., Speight, R., Song, H., Yang, Y., & Zhang, J. (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338, 1-9. Scopus23 WoS20 |
| 2021 | Yang, Y., Gu, Z., Tang, J., Zhang, M., Yang, Y., Song, H., & Yu, C. (2021). MnO<inf>2</inf> Nanoflowers Induce Immunogenic Cell Death under Nutrient Deprivation: Enabling an Orchestrated Cancer Starvation-Immunotherapy. Advanced Science, 8(4), 1-10. Scopus56 WoS55 |
| 2021 | Luo, J., Zhang, M., Yang, Y., & Yu, C. (2021). Synthesis of dendritic mesoporous organosilica nanoparticles under a mild acidic condition with homogeneous wall structure and near-neutral surface. Chemical Communications, 57(36), 4416-4419. Scopus6 WoS5 Europe PMC3 |
| 2021 | Zhang, M., Dai, Z., Theivendran, S., Gu, Z., Zhao, L., Song, H., . . . Yu, C. (2021). Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy. Nano Today, 36, 18 pages. Scopus33 WoS31 |
| 2021 | Fu, J., Jiao, J., Ban, W., Kong, Y., Gu, Z., Song, H., . . . Yu, C. (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417, 1-7. Scopus20 WoS18 |
| 2021 | Lin, X., Wu, W., Fu, J., Yang, Y., Guo, B., Yu, C., & Song, H. (2021). Asymmetric Silica Nanoparticles with Tailored Spiky Coverage Derived from Silica-Polymer Cooperative Assembly for Enhanced Hemocompatibility and Gene Delivery. ACS Applied Materials and Interfaces, 13(43), 50695-50704. Scopus17 WoS15 Europe PMC9 |
| 2021 | Song, Y., Cheng, D., Luo, J., Zhang, M., & Yang, Y. (2021). Surfactant-free synthesis of monodispersed organosilica particles with pure sulfide-bridged silsesquioxane framework chemistry via extension of Stöber method. Journal of Colloid and Interface Science, 591, 129-138. Scopus12 WoS10 Europe PMC5 |
| 2021 | Yang, Y., Zhang, M., Yang, Y., Cheng, D., & Yu, C. (2021). Designer Anticancer Nanoprodrugs with Self-Toxification Activity Realized by Acid-triggered Biodegradation and In Situ Fragment Complexation. Angewandte Chemie - International Edition, 60(20), 11504-11513. Scopus11 WoS12 Europe PMC3 |
| 2021 | Gu, Z., Liu, T., Liu, C., Yang, Y., Tang, J., Song, H., . . . Yu, C. (2021). Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities. Nano Letters, 21(15), 6471-6479. Scopus108 WoS106 Europe PMC94 |
| 2021 | Wang, Y., Song, H., Liu, C., Zhang, Y., Kong, Y., Tang, J., . . . Yu, C. (2021). Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bioregulators for enhanced mRNa delivery in vivo. National Science Review, 8(8), 10 pages. Scopus39 WoS85 Europe PMC22 |
| 2020 | Wang, Y., Yang, Y., Shi, Y., Song, H., & Yu, C. (2020). Antibiotic-Free Antibacterial Strategies Enabled by Nanomaterials: Progress and Perspectives. Advanced Materials, 32(18), 1-21. Scopus710 WoS696 Europe PMC297 |
| 2020 | Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie, 132(27), 10923-10927. |
| 2020 | Shi, Y., Fu, J., & Yang, Y. (2020). Effects of synthetic routes on the compositional and structural properties of dendritic mesoporous organosilica nanoparticles: The unexpected reversed “double-edged sword” role of reaction time. Microporous and Mesoporous Materials, 294, 1-8. Scopus6 WoS5 |
| 2020 | Song, H., Yang, Y., Tang, J., Gu, Z., Wang, Y., Zhang, M., & Yu, C. (2020). DNA Vaccine Mediated by Rambutan-Like Mesoporous Silica Nanoparticles. Advanced Therapeutics, 3(1), 12 pages. Scopus24 WoS21 |
| 2020 | Geng, J., Song, H., Gao, F., Kong, Y., Fu, J., Luo, J., . . . Yu, C. (2020). Lyophilization enabled disentanglement of polyethylenimine on rambutan-like silica nanoparticles for enhanced plasmid DNA delivery. Journal of Materials Chemistry B, 8(21), 4593-4600. Scopus6 WoS6 Europe PMC5 |
| 2020 | Tang, J., Meka, A. K., Theivendran, S., Wang, Y., Yang, Y., Song, H., . . . Yu, C. (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062. Scopus117 WoS120 Europe PMC76 |
| 2020 | Liu, Y., Kong, Y., Kumar Nanjundan, A., Yang, Y., Zhou, L., Huang, X., & Yu, C. (2020). Modulating the Void Space of Nitrogen-Doped Hollow Mesoporous Carbon Spheres for Lithium-Sulfur Batteries. ChemNanoMat, 6(6), 925-929. Scopus7 WoS7 |
| 2020 | Dai, Z., Tang, J., Gu, Z., Wang, Y., Yang, Y., Yang, Y., & Yu, C. (2020). Eliciting Immunogenic Cell Death via a Unitized Nanoinducer. Nano Letters, 20(9), 6246-6254. Scopus109 WoS107 Europe PMC75 |
| 2020 | Yang, Y., Zhang, M., Song, H., & Yu, C. (2020). Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators. Accounts of Chemical Research, 53(8), 1545-1556. Scopus202 WoS173 Europe PMC95 |
| 2020 | Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., . . . Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430. Scopus15 WoS15 Europe PMC15 |
| 2020 | Jambhrunkar, M., Yang, Y., Yu, M., Zhang, M., Abbaraju, P. L., Ghosh, T., . . . Yu, C. (2020). Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity. Materials Today Advances, 6, 8 pages. Scopus26 WoS26 |
| 2020 | Wang, Y., Tang, J., Yang, Y., Song, H., Fu, J., Gu, Z., & Yu, C. (2020). Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells. Angewandte Chemie - International Edition, 59(7), 2695-2699. Scopus58 WoS59 Europe PMC35 |
| 2020 | Yang, Y., Tang, J., Song, H., Yang, Y., Gu, Z., Fu, J., . . . Yu, C. (2020). Dendritic Mesoporous Silica Nanoparticle Adjuvants Modified with Binuclear Aluminum Complex: Coordination Chemistry Dictates Adjuvanticity. Angewandte Chemie - International Edition, 59(44), 19610-19617. Scopus37 WoS37 Europe PMC16 |
| 2020 | Zhang, M., Yang, Y., Liu, Y., Fu, J., Lu, J., Yang, Y., . . . Yu, C. (2020). 3D-Nanosponge enabled segregation: A versatile approach for highly dispersed and high content functionalization of metal oxide species. Materials Chemistry Frontiers, 4(6), 1739-1746. Scopus4 WoS3 |
| 2020 | Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie - International Edition, 59(27), 10831-10835. Scopus134 WoS132 Europe PMC66 |
| 2019 | Theivendran, S., Zhang, J., Tang, C., Kalantari, M., Gu, Z., Yang, Y., . . . Yu, C. (2019). Synthesis of biphenyl bridged dendritic mesoporous organosilica with extremely high adsorption of pyrene. Journal of Materials Chemistry A, 7(19), 12029-12037. Scopus25 WoS24 |
| 2019 | Gu, Z., Liu, T., Tang, J., Yang, Y., Song, H., Tuong, Z. K., . . . Yu, C. (2019). Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway. Journal of the American Chemical Society, 141(15), 6122-6126. Scopus166 WoS157 Europe PMC113 |
| 2019 | Yang, Y., Tang, J., Zhang, M., Gu, Z., Song, H., Yang, Y., & Yu, C. (2019). Responsively Aggregatable Sub-6 nm Nanochelators Induce Simultaneous Antiangiogenesis and Vascular Obstruction for Enhanced Tumor Vasculature Targeted Therapy. Nano Letters, 19(11), 7750-7759. Scopus40 WoS34 Europe PMC22 |
| 2019 | Song, H., Yang, Y., Geng, J., Gu, Z., Zou, J., & Yu, C. (2019). Electron Tomography: A Unique Tool Solving Intricate Hollow Nanostructures. Advanced Materials, 31(38), 1801564. Scopus43 WoS44 Europe PMC19 |
| 2019 | Fu, J., Gu, Z., Liu, Y., Zhang, J., Song, H., Yang, Y., . . . Yu, C. (2019). Bottom-up self-assembly of heterotrimeric nanoparticles and their secondary Janus generations. Chemical Science, 10(44), 10388-10394. Scopus37 WoS33 Europe PMC10 |
| 2018 | Lu, Y., Yang, Y., Gu, Z., Zhang, J., Song, H., Xiang, G., & Yu, C. (2018). Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy. Biomaterials, 175, 82-92. Scopus161 WoS149 Europe PMC102 |
| 2018 | Zhang, M., Yang, Y., & Yu, C. (2018). Nano-resoles-Enabled Elegant Nanostructured Materials. Chemistry A European Journal, 24(55), 14598-14607. Scopus8 WoS7 Europe PMC1 |
| 2018 | Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off‐the‐Shelf Strategy for Concurrently Enhanced Chemo‐immunotherapy. Angewandte Chemie, 130(36), 11938-11943. |
| 2018 | Yang, Y., Lu, Y., Abbaraju, P. L., Azimi, I., Lei, C., Tang, J., . . . Yu, C. (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1-11. Scopus114 WoS110 |
| 2018 | Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., & Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019. Scopus6 WoS7 Europe PMC3 |
| 2018 | Liu, C., Huang, X., Wang, J., Song, H., Yang, Y., Liu, Y., . . . Yu, C. (2018). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28(6), 1-8. Scopus140 WoS129 |
| 2018 | Kalantari, M., Yu, M., Jambhrunkar, M., Liu, Y., Yang, Y., Huang, X., & Yu, C. (2018). Designed synthesis of organosilica nanoparticles for enzymatic biodiesel production. Materials chemistry frontiers, 2(7), 1334-1342. Scopus31 WoS29 |
| 2018 | Abbaraju, P. L., Jambhrunkar, M., Yang, Y., Liu, Y., Lu, Y., & Yu, C. (2018). Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses. Chemical communications, 54(16), 2020-2023. Scopus51 WoS44 Europe PMC28 |
| 2018 | Zhang, M., Song, H., Yang, Y., Huang, X., Liu, Y., Liu, C., & Yu, C. (2018). Oxidative Dissolution of Resoles: A Versatile Approach to Intricate Nanostructures. Angewandte Chemie International Edition, 57(3), 654-658. Scopus17 WoS16 Europe PMC9 |
| 2018 | Kalantari, M., Liu, Y., Strounina, E., Yang, Y., Song, H., & Yu, C. (2018). Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties. Journal of Materials Chemistry A, 6(36), 17579-17586. Scopus21 WoS20 |
| 2018 | Wang, Y., Song, H., Yu, M., Xu, C., Liu, Y., Tang, J., . . . Yu, C. (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6(24), 4089-4095. Scopus72 WoS69 Europe PMC44 |
| 2018 | Wang, Y., Song, H., Yang, Y., Liu, Y., Tang, J., & Yu, C. (2018). Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling. Chemistry of Materials, 30(16), 5770-5776. Scopus47 WoS46 |
| 2018 | Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769. Scopus108 WoS111 Europe PMC70 |
| 2018 | Pan, D., Chen, W., Huang, X., Zhang, J., Yang, Y., Yu, F., . . . Yu, C. (2018). Solvothermal-assisted evaporation-induced self-assembly of ordered mesoporous alumina with improved performance. Journal of Colloid and Interface Science, 529, 432-443. Scopus23 WoS20 Europe PMC6 |
| 2017 | Jiao, J., Fu, J., Wei, Y., Zhao, Z., Duan, A., Xu, C., . . . Liu, Y. (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal–support interaction. Journal of Catalysis, 356, 269-282. Scopus107 WoS102 |
| 2017 | Abbaraju, P. L., Meka, A. K., Song, H., Yang, Y., Jambhrunkar, M., Zhang, J., . . . Yu, C. (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American chemical society, 139(18), 6321-6328. Scopus129 WoS126 Europe PMC62 |
| 2017 | Kalantari, M., Yu, M., Yang, Y., Strounina, E., Gu, Z., Huang, X., . . . Yu, C. (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10(2), 605-617. Scopus71 WoS68 |
| 2017 | Purwajanti, S., Huang, X., Liu, Y., Yang, Y., Noonan, O., Song, H., . . . Yu, C. (2017). Mg(OH)2-MgO@reduced graphene oxide nanocomposites: The roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry A, 5(46), 24484-24492. Scopus28 WoS27 |
| 2017 | Abbaraju, P. L., Yang, Y., Yu, M., Fu, J., Xu, C., & Yu, C. (2017). Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery. Chemistry an Asian Journal, 12(13), 1465-1469. Scopus24 WoS20 Europe PMC8 |
| 2017 | Lin, C. X. C., Xu, C., Yang, Y., Lei, C., Zhang, H., & Yu, C. (2017). Dendritic mesoporous silica-titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760. Scopus18 WoS17 |
| 2017 | Yang, Y., Jambhrunkar, M., Abbaraju, P. L., Yu, M., Zhang, M., & Yu, C. (2017). Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency. Advanced healthcare materials, 6(17, article no. 1700466), 1-12. Scopus42 WoS44 Europe PMC24 |
| 2017 | Song, H., Yu, M., Lu, Y., Gu, Z., Yang, Y., Zhang, M., . . . Yu, C. (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139(50), 18247-18254. Scopus130 WoS120 Europe PMC84 |
| 2017 | Yang, Y., Lu, Y., Abbaraju, P. L., Zhang, J., Zhang, M., Xiang, G., & Yu, C. (2017). Multi-shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy. Angewandte Chemie International Edition, 56(29), 8446-8450. Scopus143 WoS146 Europe PMC68 |
| 2016 | Yang, Y., Bernardi, S., Song, H., Zhang, J., Yu, M., Reid, J. C., . . . Yu, C. (2016). Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient. Chemistry of Materials, 28(3), 704-707. Scopus228 WoS223 |
| 2016 | Hartono, S. B., Hadisoewignyo, L., Yang, Y., Meka, A. K., Antaresti., & Yu, C. (2016). Amine functionalized cubic mesoporous silica nanoparticles as an oral delivery system for curcumin bioavailability enhancement. NANOTECHNOLOGY, 27(50), 7 pages. WoS51 Europe PMC24 |
| 2016 | Song, H., Ahmad Nor, Y., Yu, M., Yang, Y., Zhang, J., Zhang, H., . . . Yu, C. (2016). Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition. Journal of the American Chemical Society, 138(20), 6455-6462. Scopus265 WoS254 Europe PMC138 |
| 2016 | Yang, Y., Wan, J., Niu, Y., Gu, Z., Zhang, J., Yu, M., & Yu, C. (2016). Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery. Chemistry of Materials, 28(24), 9008-9016. Scopus161 WoS157 |
| 2016 | Yang, Y., & Yu, C. (2016). Advances in silica based nanoparticles for targeted cancer therapy. Nanomedicine Nanotechnology Biology and Medicine, 12(2), 317-332. Scopus175 WoS146 Europe PMC96 |
| 2016 | Yu, M., Niu, Y., Zhang, J., Zhang, H., Yang, Y., Taran, E., . . . Yu, C. (2016). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9(2), 291-305. Scopus37 WoS36 |
| 2016 | Zhang, H., Noonan, O., Huang, X., Yang, Y., Xu, C., Zhou, L., & Yu, C. (2016). Surfactant-Free Assembly of Mesoporous Carbon Hollow Spheres with Large Tunable Pore Sizes. ACS Nano, 10(4), 4579-4586. Scopus453 WoS439 Europe PMC132 |
| 2016 | Wang, Y., Nor, Y. A., Song, H., Yang, Y., Xu, C., Yu, M., & Yu, C. (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4(15), 2646-2653. Scopus98 WoS95 Europe PMC51 |
| 2016 | Purwajanti, S., Zhang, H., Huang, X., Song, H., Yang, Y., Zhang, J., . . . Yu, C. (2016). Mesoporous Magnesium Oxide Hollow Spheres as Superior Arsenite Adsorbent: Synthesis and Adsorption Behavior. ACS Applied Materials and Interfaces, 8(38), 25306-25312. Scopus83 WoS77 Europe PMC20 |
| 2016 | Liu, Y., Zhang, H., Noonan, O., Xu, C., Niu, Y., Yang, Y., . . . Yu, C. (2016). Kinetically Controlled Assembly of Nitrogen-Doped Invaginated Carbon Nanospheres with Tunable Mesopores. Chemistry A European Journal, 22(42), 14962-14967. Scopus23 WoS22 Europe PMC7 |
| 2015 | Niu, Y., Yu, M., Zhang, J., Yang, Y., Xu, C., Yeh, M., . . . Yu, C. (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3(43), 8477-8485. Scopus42 WoS40 Europe PMC21 |
| 2015 | Yang, Y., Yu, M., Song, H., Wang, Y., & Yu, C. (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7(28), 11894-11898. Scopus27 WoS25 Europe PMC13 |
| 2015 | Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., . . . Yu, C. (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955. Scopus164 WoS156 Europe PMC92 |
| 2015 | Yang, Y., Niu, Y., Zhang, J., Meka, A. K., Zhang, H., Xu, C., . . . Yu, C. (2015). Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery. Small, 11(23), 2743-2749. Scopus80 WoS80 Europe PMC51 |
| 2015 | Zhang, H., Yu, M., Song, H., Noonan, O., Zhang, J., Yang, Y., . . . Yu, C. (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27(18), 6297-6304. Scopus108 WoS107 |
| 2015 | Niu, Y., Yu, M., Meka, A., Liu, Y., Zhang, J., Yang, Y., & Yu, C. (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4(2), 212-219. Scopus85 WoS83 Europe PMC49 |
| 2014 | Yu, M., Niu, Y., Yang, Y., Hartono, S. B., Yang, J., Huang, X., . . . Yu, C. (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6(18), 15626-15631. Scopus20 WoS19 Europe PMC11 |
| 2014 | Yang, Y., Karmakar, S., Yu, M., Popat, A., & Yu, C. (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, 43(3), 316-318. Scopus2 WoS2 |
| 2014 | Yang, Y., Karmakar, S., Zhang, J., Yu, M., Mitter, N., & Yu, C. (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2(30), 4929-4934. Scopus25 WoS24 Europe PMC10 |
| 2014 | Zhang, J., Raphael, A. P., Yang, Y., Popat, A., Prow, T. W., & Yu, C. (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of materials chemistry, 2(44), 7673-7678. Scopus17 WoS16 Europe PMC8 |
| 2014 | Yu, M., Karmakar, S., Yang, J., Zhang, H., Yang, Y., Thorn, P., & Yu, C. (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids. Chemical Communications, 50(13), 1527-1529. Scopus17 WoS19 Europe PMC9 |
| Year | Citation |
|---|---|
| - | Yang, Y. (n.d.). Development of a mesoporous silica based nanosystem for safe and efficient therapeutic delivery. |
- NHMRC Emerging Leadership Fellow (EL1), 2022-2026, Sole CI, $650,740
- ARC Discovery Project 2020-2023, CI B, $395,000
- UQ-Early Career Researcher Grant 2020.1-2020.12, Sole CI, $20,000
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Principal Supervisor | Bioengineered Therapeutic Platforms for Cancer Immunotherapy | Doctor of Philosophy | Doctorate | Full Time | Miss Yuxuan Hou |
| 2025 | Principal Supervisor | Bioengineered Therapeutic Platforms for Cancer Immunotherapy | Doctor of Philosophy | Doctorate | Full Time | Miss Yuxuan Hou |
| 2024 | Principal Supervisor | Reprogramming Tumor-Associated Macrophages with mRNA Encapsulated Plant-Based Virus-like Nanoparticles for Immunotherapy of Triple Negative Breast Cancer | Master of Philosophy (Medical Science) | Master | Full Time | Miss Uta Ishikawa |
| 2024 | Principal Supervisor | Reprogramming Tumor-Associated Macrophages with mRNA Encapsulated Plant-Based Virus-like Nanoparticles for Immunotherapy of Triple Negative Breast Cancer | - | Master | Full Time | Miss Uta Ishikawa |
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