Yannan Yang

Dr Yannan Yang

Group Leader, Biomat & Immune Eng Lab (BIEL)

South Australian Immunogenomics Cancer Institute

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Yannan Yang completed PhD (Biomedical Engineering) in Australian Institute of Bioengineering and Nanotechnology/University of Queensland in 2019 before taking a postdoctoral research follow position in the same institute. In 2023, he established his own research group (Biomaterials and Immune Engineering Laboratory - BIEL) in SAiGENCI in the University of Adelaide. He has developed innovative synthetic approaches for biomaterials and nanoparticles with controllable architecture and composition, and demonstrated the great potential of materials based cancer immunotherapy. Dr Yang's vision is to develop novel biomaterials-enabled vaccine technology for cancer immunotherapy and promote the clinic translation of the technology to significantly improve the treatment outcome of cancers with poor prognosis.

Dr Yannan Yang is the head of Biomaterials and Immune Engineering Laboratory (BIEL). BIEL aims to leverage state-of-the-art biomaterials and nanotechnology-based approaches to modulate immune system and create translational immunotherapy strategies with improved therapeutic efficacy and minimized adverse effects. Our laboratory is specifically interested in designing and fabricating biocompatible nanoparticles, hydrogels, scaffolds and cell/bacteria derived biomimetic materials with immunomodulatory activities and controlled drug release profile for engineering immunity. We stand at the materials-bio interface and investigate how biomaterials at different scales (nano, micro and bulk) can interact with bio-systems and tumour microenvironment, and how these interactions can be further controlled to benefit the outcome of immunotherapy that aims to prevent and treat cancer.

  • Journals
    Year Citation
    2025 Gong, Y., Zhang, H., Lu, M., Sun, J., Jia, Y., Yang, Y., . . . Ling, Y. (2025). Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications. Journal of Colloid and Interface Science, 679(Pt B), 412-421.
    DOI Scopus4 Europe PMC1
    2025 Luo, D., Wu, T., Qiu, T., Li, J., Gong, Y., Weng, J., . . . Zhou, Y. (2025). Coordination-Dissociation Induced T<inf>1</inf>-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring. Advanced Functional Materials.
    DOI
    2024 Zhang, M., Lu, M., Gong, Y., Yang, Y., Song, J., Li, J., . . . Zhou, Y. (2024). Tadpole-Like Carbon Nanotube with Fe Nanoparticle Encapsulated at the Head and Zn Single-Atom Anchored on the Body: One-Pot Carbonization for Tetramodal Synergistic Cancer Therapy. Small, 20(40), e2400587.
    DOI Scopus2
    2024 Huang, Y., Zou, J., Huo, J., Zhang, M., & Yang, Y. (2024). Sulfate Radical Based In Situ Vaccine Boosts Systemic Antitumor Immunity via Concurrent Activation of Necroptosis and STING Pathway. Advanced Materials, 36(41), e2407914-1-e2407914-15.
    DOI Scopus5 Europe PMC1
    2024 Zhang, Y., Yao, Y., Xie, F., Hu, W. L., Zou, Y., Zhao, Q., . . . Yu, C. (2024). Iron consumption strengthens anti-tumoral STING activation mediated by manganese-based nanoparticles. Nano Today, 58, 102446.
    DOI Scopus2
    2024 Huo, J., Zou, J., Ma, H., Meng, G., Huang, Y., Yan, X., . . . Zhang, M. (2024). Astragaloside IV microfibers assembling into injectable 3D-scaffolds with intrinsic immunoactivity for enhanced tumor vaccine efficacy. Chemical Engineering Journal, 498, 155511-1-155511-13.
    DOI
    2024 Lu, W., Wang, W., Gong, Y., Li, J., Zhou, Y., & Yang, Y. (2024). A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis.. Small, 20(49), 2407676-1-2407676-12.
    DOI Scopus2 Europe PMC3
    2024 Jin, Y., Hu, C., Xia, J., Xie, D., Ye, L., Ye, X., . . . Hu, Z. (2024). Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization. Bioactive Materials, 42, 613-627.
    DOI Scopus1
    2024 Li, J., Wu, T., Wang, W., Gong, Y., Lu, M., Zhang, M., . . . Yang, Y. (2024). Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines. Science Advances, 10(38), eadn3002-1-eadn3002-15.
    DOI Scopus2 Europe PMC1
    2024 Brown, D. A., Reid, A., Jagodzinski, E. A., Williams, M., Simpson, A., Pawley, M., . . . Glorie, S. (2024). Testing in-situ apatite Lu-Hf dating in polymetamorphic mafic rocks: a case study from Palaeoproterozoic southern Australia. Contributions to Mineralogy and Petrology, 179(5), 46-1-46-25.
    DOI Scopus3
    2024 Gallagher, S., Attinger, S., Sassano, A., Sutton, E., Kerridge, I., Newson, A., . . . Lipworth, W. (2024). Medicine in the marketplace: clinician and patient views on commercial influences on assisted reproductive technology. Reproductive BioMedicine Online, 48(6), 103850-1-103850-9.
    DOI Scopus4 Europe PMC2
    2024 Hamilton, S., Oxlad, M., & Sianis, Y. (2024). Experiences of women with breast cancer disclosing cancer-related cognitive impairment symptoms to health professionals: a Systematic review and meta-synthesis. Journal of Psychosocial Oncology, 42(6), 888-908.
    DOI
    2024 Zhang, Y., Yu, Y., Yang, Y., Wang, Y., & Yu, C. (2024). Engineered Silica Nanoparticles for Nucleic Acid Delivery. Small Methods, 8(3), 2300812-1-2300812-16.
    DOI Scopus4 Europe PMC2
    2024 Yang, Y., Chen, S., Zhang, M., Shi, Y., Luo, J., Huang, Y., . . . Yu, C. (2024). Mesoporous nanoperforators as membranolytic agents via nano- and molecular-scale multi-patterning.. Nat Commun, 15(1), 1891.
    DOI Scopus2 Europe PMC2
    2024 Singh, P., Teixeira, J. C., Bolch, C., & Armbrecht, L. (2024). Marine sedimentary ancient DNA from Antarctic diatoms. Palaeogeography, Palaeoclimatology, Palaeoecology, 640, 112090-1-112090-9.
    DOI Scopus1
    2024 Ho, H. T., Jia, R., Habibi, N., Stern, C., Carter, G., Santin, O., . . . Aromataris, E. (2024). Experiences of informal caregivers of people with dementia in low- and middle-income countries: A systematic review protocol. JBI Evidence Synthesis, 22(7), 1362-1370.
    DOI
    2024 Thorsteinsson, E. B., Cosh, S. M., & Loi, N. M. (2024). Older individuals and preventative behavioural interventions for COVID-19: a scoping review and perspective on wellbeing. Journal of Global Health Reports, 8.
    DOI
    2023 Zhang, M., Lu, M., Qiu, T., Wang, Q., Chen, Z., Deng, M., . . . Zhou, Y. (2023). Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications. Small, 19(34), e2301894.
    DOI Scopus18 Europe PMC3
    2023 Zhang, M., Huang, Y., Zou, J., Yang, Y., Yao, Y., Cheng, G., & Yang, Y. (2023). Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Advanced Science, 10(22), 10 pages.
    DOI Scopus8 Europe PMC5
    2023 Li, J., Lu, W., Yang, Y., Xiang, R., Ling, Y., Yu, C., & Zhou, Y. (2023). Hybrid Nanomaterials for Cancer Immunotherapy. Advanced Science, 10(6), 42 pages.
    DOI Scopus70 WoS13 Europe PMC39
    2023 Zhang, M., Wu, T., Zhang, H., Chen, Z., Yang, Y., Ling, Y., & Zhou, Y. (2023). Mesoporous carbon hemispheres integrated with Fe-Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy. Journal of Materials Chemistry B, 12(3), 9 pages.
    DOI Scopus2 Europe PMC1
    2023 Shi, Y., Dai, Z., Wang, Y., Luo, J., Cai, L., Tang, J., . . . Yang, Y. (2023). Engineering Crystallinity Gradients for Tailored CaO₂ Nanostructures: Enabling Alkalinity-Reinforced Anticancer Activity with Minimized Ca²⁺/H₂O₂ Production. Nano letters, 23(23), 10657-10666.
    DOI Scopus3
    2022 Tang, J., Yang, Y., Qu, J., Ban, W., Song, H., Gu, Z., . . . Yu, C. (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13(29), 8507-8517.
    DOI Scopus18 WoS7 Europe PMC13
    2022 Wang, F. Y., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie - International Edition, 61(41), 12 pages.
    DOI Scopus9 WoS2 Europe PMC3
    2022 Theivendran, S., Gu, Z., Tang, J., Yang, Y., Song, H., Yang, Y., . . . Yu, C. (2022). Nanostructured Organosilica Nitric Oxide Donors Intrinsically Regulate Macrophage Polarization with Antitumor Effect. ACS Nano, 16(7), 10943-10957.
    DOI Scopus62 WoS21 Europe PMC21
    2022 Yu, Z., Fang, W., Yang, Y., Yao, H., Hu, P., & Shi, J. (2022). Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an Example. Advanced Healthcare Materials, 11(17), 9 pages.
    DOI Scopus3 Europe PMC2
    2022 Zhang, M., Feng, J., Zhong, Y., Luo, J., Zhao, Y., Yang, Y., . . . Yu, C. (2022). In-situ synthesis of Drug-Containing bactericidal rough silica nanoparticles for antibacterial coating. Chemical Engineering Journal, 440, 1-11.
    DOI Scopus20 WoS5
    2022 Wang, F., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie, 134(41).
    DOI
    2022 Zhao, L., Zhang, Y., Yang, Y., & Yu, C. (2022). Silica-based Nanoparticles for Enzyme Immobilization and Delivery. Chemistry - An Asian Journal, 17(17), 1-9.
    DOI Scopus19 WoS5 Europe PMC4
    2022 Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., . . . Yu, C. (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 1-8.
    DOI Scopus27 WoS7 Europe PMC14
    2022 Dai, Z., Wang, Q., Tang, J., Qu, R., Wu, M., Li, H., . . . Yu, C. (2022). A Sub-6 nm MnFe<inf>2</inf>O<inf>4</inf>-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy. Biomaterials, 284, 11 pages.
    DOI Scopus32 WoS11 Europe PMC18
    2022 Dai, Z., Wang, Q., Tang, J., Wu, M., Li, H., Yang, Y., . . . Yu, C. (2022). Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy. Biomaterials, 280, 121261-1-121261-13.
    DOI Scopus45 WoS18 Europe PMC22
    2022 Kothalawala, S. G., Jiao, J., Speight, R., Song, H., Yang, Y., & Zhang, J. (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338, 1-9.
    DOI Scopus15
    2021 Yang, Y., Gu, Z., Tang, J., Zhang, M., Yang, Y., Song, H., & Yu, C. (2021). MnO<inf>2</inf> Nanoflowers Induce Immunogenic Cell Death under Nutrient Deprivation: Enabling an Orchestrated Cancer Starvation-Immunotherapy. Advanced Science, 8(4), 1-10.
    DOI Scopus49
    2021 Luo, J., Zhang, M., Yang, Y., & Yu, C. (2021). Synthesis of dendritic mesoporous organosilica nanoparticles under a mild acidic condition with homogeneous wall structure and near-neutral surface. Chemical Communications, 57(36), 4416-4419.
    DOI Scopus5 WoS4 Europe PMC1
    2021 Fu, J., Jiao, J., Ban, W., Kong, Y., Gu, Z., Song, H., . . . Yu, C. (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417, 1-7.
    DOI Scopus14 WoS6
    2021 Lin, X., Wu, W., Fu, J., Yang, Y., Guo, B., Yu, C., & Song, H. (2021). Asymmetric Silica Nanoparticles with Tailored Spiky Coverage Derived from Silica-Polymer Cooperative Assembly for Enhanced Hemocompatibility and Gene Delivery. ACS Applied Materials and Interfaces, 13(43), 50695-50704.
    DOI Scopus16 WoS11 Europe PMC5
    2021 Zhang, M., Dai, Z., Theivendran, S., Gu, Z., Zhao, L., Song, H., . . . Yu, C. (2021). Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy. Nano Today, 36, 18 pages.
    DOI Scopus34 WoS21
    2021 Song, Y., Cheng, D., Luo, J., Zhang, M., & Yang, Y. (2021). Surfactant-free synthesis of monodispersed organosilica particles with pure sulfide-bridged silsesquioxane framework chemistry via extension of Stöber method. Journal of Colloid and Interface Science, 591, 129-138.
    DOI Scopus10 WoS4 Europe PMC3
    2021 Yang, Y., Zhang, M., Yang, Y., Cheng, D., & Yu, C. (2021). Designer Anticancer Nanoprodrugs with Self-Toxification Activity Realized by Acid-triggered Biodegradation and In Situ Fragment Complexation. Angewandte Chemie - International Edition, 60(20), 11504-11513.
    DOI Scopus11 WoS5 Europe PMC2
    2021 Gu, Z., Liu, T., Liu, C., Yang, Y., Tang, J., Song, H., . . . Yu, C. (2021). Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities. Nano Letters, 21(15), 6471-6479.
    DOI Scopus95 WoS51 Europe PMC59
    2021 Wang, Y., Song, H., Liu, C., Zhang, Y., Kong, Y., Tang, J., . . . Yu, C. (2021). Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bioregulators for enhanced mRNa delivery in vivo. National Science Review, 8(8), 10 pages.
    DOI Scopus33 WoS39 Europe PMC12
    2020 Wang, Y., Yang, Y., Shi, Y., Song, H., & Yu, C. (2020). Antibiotic-Free Antibacterial Strategies Enabled by Nanomaterials: Progress and Perspectives. Advanced Materials, 32(18), 1-21.
    DOI Scopus645 WoS396 Europe PMC176
    2020 Tang, J., Meka, A. K., Theivendran, S., Wang, Y., Yang, Y., Song, H., . . . Yu, C. (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062.
    DOI Scopus105 WoS64 Europe PMC42
    2020 Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie, 132(27), 10923-10927.
    DOI
    2020 Shi, Y., Fu, J., & Yang, Y. (2020). Effects of synthetic routes on the compositional and structural properties of dendritic mesoporous organosilica nanoparticles: The unexpected reversed “double-edged sword” role of reaction time. Microporous and Mesoporous Materials, 294, 1-8.
    DOI Scopus6 WoS4
    2020 Song, H., Yang, Y., Tang, J., Gu, Z., Wang, Y., Zhang, M., & Yu, C. (2020). DNA Vaccine Mediated by Rambutan-Like Mesoporous Silica Nanoparticles. Advanced Therapeutics, 3(1), 12 pages.
    DOI Scopus21 WoS11
    2020 Liu, Y., Kong, Y., Kumar Nanjundan, A., Yang, Y., Zhou, L., Huang, X., & Yu, C. (2020). Modulating the Void Space of Nitrogen-Doped Hollow Mesoporous Carbon Spheres for Lithium-Sulfur Batteries. ChemNanoMat, 6(6), 925-929.
    DOI Scopus7 WoS7
    2020 Wang, Y., Tang, J., Yang, Y., Song, H., Fu, J., Gu, Z., & Yu, C. (2020). Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells. Angewandte Chemie - International Edition, 59(7), 2695-2699.
    DOI Scopus53 WoS42 Europe PMC21
    2020 Geng, J., Song, H., Gao, F., Kong, Y., Fu, J., Luo, J., . . . Yu, C. (2020). Lyophilization enabled disentanglement of polyethylenimine on rambutan-like silica nanoparticles for enhanced plasmid DNA delivery. Journal of Materials Chemistry B, 8(21), 4593-4600.
    DOI Scopus5 WoS4 Europe PMC2
    2020 Dai, Z., Tang, J., Gu, Z., Wang, Y., Yang, Y., Yang, Y., & Yu, C. (2020). Eliciting Immunogenic Cell Death via a Unitized Nanoinducer. Nano Letters, 20(9), 6246-6254.
    DOI Scopus104 WoS60 Europe PMC42
    2020 Yang, Y., Zhang, M., Song, H., & Yu, C. (2020). Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators. Accounts of Chemical Research, 53(8), 1545-1556.
    DOI Scopus171 WoS92 Europe PMC59
    2020 Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., . . . Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430.
    DOI Scopus15 WoS10 Europe PMC14
    2020 Jambhrunkar, M., Yang, Y., Yu, M., Zhang, M., Abbaraju, P. L., Ghosh, T., . . . Yu, C. (2020). Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity. Materials Today Advances, 6, 8 pages.
    DOI Scopus25 WoS14
    2020 Yang, Y., Tang, J., Song, H., Yang, Y., Gu, Z., Fu, J., . . . Yu, C. (2020). Dendritic Mesoporous Silica Nanoparticle Adjuvants Modified with Binuclear Aluminum Complex: Coordination Chemistry Dictates Adjuvanticity. Angewandte Chemie - International Edition, 59(44), 19610-19617.
    DOI Scopus33 Europe PMC11
    2020 Zhang, M., Yang, Y., Liu, Y., Fu, J., Lu, J., Yang, Y., . . . Yu, C. (2020). 3D-Nanosponge enabled segregation: A versatile approach for highly dispersed and high content functionalization of metal oxide species. Materials Chemistry Frontiers, 4(6), 1739-1746.
    DOI Scopus4
    2020 Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie - International Edition, 59(27), 10831-10835.
    DOI Scopus125 Europe PMC33
    2020 Sun, J., Wang, Z., Luo, X., Shi, P., Wang, W., Wang, L., . . . Zhao, W. (2020). A Parallel Recommender System Using a Collaborative Filtering Algorithm with Correntropy for Social Networks. IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING, 7(1), 91-103.
    DOI WoS13
    2020 Shi, P., Guan, W., & Wang, J. (2020). Analytical expressions of the dynamic permeability and electrokinetic coupling coefficient in fluid-saturated rock. CHINESE JOURNAL OF GEOPHYSICS-CHINESE EDITION, 63(4), 1695-1704.
    DOI WoS1
    2019 Shi, P., Li, N., Wang, S., Liu, Z., Ren, M., & Ma, H. (2019). Quantum Multi-User Broadcast Protocol for the "Platform as a Service" Model. SENSORS, 19(23), 11 pages.
    DOI WoS15
    2019 Zhao, Z., Jin, Y., Shi, P., Xue, Y., Zhao, B., Zhang, Y., . . . Wang, Q. (2019). An Improved High-Throughput Data Processing Based on Combinatorial Materials Chip Approach for Rapid Construction of Fe-Cr-Ni Composition-Phase Map. ACS COMBINATORIAL SCIENCE, 21(12), 833-842.
    DOI WoS6
    2019 Li, Y., Li, J., Shi, P., & Qin, X. (2019). Building an Open Cloud Virtual Dataspace Model for Materials Scientific Data. INTELLIGENT AUTOMATION AND SOFT COMPUTING, 25(3), 615-624.
    DOI WoS3
    2019 Shi, P., Cui, Y., Xu, K., Zhang, M., & Ding, L. (2019). Data Consistency Theory and Case Study for Scientific Big Data. INFORMATION, 10(4), 15 pages.
    DOI WoS8
    2019 Gu, Z., Liu, T., Tang, J., Yang, Y., Song, H., Tuong, Z. K., . . . Yu, C. (2019). Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway. Journal of the American Chemical Society, 141(15), 6122-6126.
    DOI Scopus150 WoS100 Europe PMC64
    2019 Theivendran, S., Zhang, J., Tang, C., Kalantari, M., Gu, Z., Yang, Y., . . . Yu, C. (2019). Synthesis of biphenyl bridged dendritic mesoporous organosilica with extremely high adsorption of pyrene. Journal of Materials Chemistry A, 7(19), 12029-12037.
    DOI Scopus24 WoS21
    2019 Yang, Y., Tang, J., Zhang, M., Gu, Z., Song, H., Yang, Y., & Yu, C. (2019). Responsively Aggregatable Sub-6 nm Nanochelators Induce Simultaneous Antiangiogenesis and Vascular Obstruction for Enhanced Tumor Vasculature Targeted Therapy. Nano Letters, 19(11), 7750-7759.
    DOI Scopus36 WoS20 Europe PMC12
    2019 Song, H., Yang, Y., Geng, J., Gu, Z., Zou, J., & Yu, C. (2019). Electron Tomography: A Unique Tool Solving Intricate Hollow Nanostructures. Advanced Materials, 31(38), 1801564.
    DOI Scopus42 WoS43 Europe PMC9
    2019 Fu, J., Gu, Z., Liu, Y., Zhang, J., Song, H., Yang, Y., . . . Yu, C. (2019). Bottom-up self-assembly of heterotrimeric nanoparticles and their secondary Janus generations. Chemical Science, 10(44), 10388-10394.
    DOI Scopus32 WoS20 Europe PMC3
    2018 Lu, Y., Yang, Y., Gu, Z., Zhang, J., Song, H., Xiang, G., & Yu, C. (2018). Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy. Biomaterials, 175, 82-92.
    DOI Scopus152 WoS115 Europe PMC52
    2018 Zhang, M., Yang, Y., & Yu, C. (2018). Nano-resoles-Enabled Elegant Nanostructured Materials. Chemistry - A European Journal, 24(55), 14598-14607.
    DOI Scopus8 WoS7
    2018 Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off‐the‐Shelf Strategy for Concurrently Enhanced Chemo‐immunotherapy. Angewandte Chemie, 130(36), 11938-11943.
    DOI
    2018 Yang, Y., Lu, Y., Abbaraju, P. L., Azimi, I., Lei, C., Tang, J., . . . Yu, C. (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1-11.
    DOI Scopus111 WoS94
    2018 Niu, L., Zhu, X., Pan, M., Derek, A., Xu, L., Meng, L., & Zheng, H. (2018). Influence of vascular geometry on local hemodynamic parameters: Phantom and small rodent study. BioMedical Engineering Online, 17(1), 10 pages.
    DOI Scopus7 Europe PMC5
    2018 Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., & Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019.
    DOI Scopus6 Europe PMC2
    2018 Wang, Y., Song, H., Yu, M., Xu, C., Liu, Y., Tang, J., . . . Yu, C. (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6(24), 4089-4095.
    DOI Scopus64 WoS39 Europe PMC27
    2018 Kalantari, M., Liu, Y., Strounina, E., Yang, Y., Song, H., & Yu, C. (2018). Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties. Journal of Materials Chemistry A, 6(36), 17579-17586.
    DOI Scopus20 WoS14
    2018 Abbaraju, P. L., Jambhrunkar, M., Yang, Y., Liu, Y., Lu, Y., & Yu, C. (2018). Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses. Chemical Communications, 54(16), 2020-2023.
    DOI Scopus49 WoS35 Europe PMC16
    2018 Zhang, M., Song, H., Yang, Y., Huang, X., Liu, Y., Liu, C., & Yu, C. (2018). Oxidative Dissolution of Resoles: A Versatile Approach to Intricate Nanostructures. Angewandte Chemie - International Edition, 57(3), 654-658.
    DOI Scopus17 WoS14 Europe PMC2
    2018 Liu, C., Huang, X., Wang, J., Song, H., Yang, Y., Liu, Y., . . . Yu, C. (2018). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28(6), 1-8.
    DOI Scopus135 WoS101
    2018 Kalantari, M., Yu, M., Jambhrunkar, M., Liu, Y., Yang, Y., Huang, X., & Yu, C. (2018). Designed synthesis of organosilica nanoparticles for enzymatic biodiesel production. Materials Chemistry Frontiers, 2(7), 1334-1342.
    DOI Scopus30 WoS22
    2018 Wang, Y., Song, H., Yang, Y., Liu, Y., Tang, J., & Yu, C. (2018). Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling. Chemistry of Materials, 30(16), 5770-5776.
    DOI Scopus45
    2018 Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769.
    DOI Scopus102 WoS90 Europe PMC36
    2018 Pan, D., Chen, W., Huang, X., Zhang, J., Yang, Y., Yu, F., . . . Yu, C. (2018). Solvothermal-assisted evaporation-induced self-assembly of ordered mesoporous alumina with improved performance. Journal of Colloid and Interface Science, 529, 432-443.
    DOI Scopus17 Europe PMC3
    2018 Triplett, J., Hee, G., McLean-Tooke, A., & Lucas, M. (2018). Long-term control of laryngeal plasma cell mucositis with systemic immunosuppression. BMJ Case Reports, 2018, bcr-2017-221333.
    DOI Scopus3 Europe PMC1
    2017 Abbaraju, P. L., Meka, A. K., Song, H., Yang, Y., Jambhrunkar, M., Zhang, J., . . . Yu, C. (2017). Asymmetric Silica Nanoparticles with Tunable Head-Tail Structures Enhance Hemocompatibility and Maturation of Immune Cells. Journal of the American Chemical Society, 139(18), 6321-6328.
    DOI Scopus123 WoS94 Europe PMC43
    2017 Kalantari, M., Yu, M., Yang, Y., Strounina, E., Gu, Z., Huang, X., . . . Yu, C. (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10(2), 605-617.
    DOI Scopus68 WoS57
    2017 Lin, C. X. C., Xu, C., Yang, Y., Lei, C., Zhang, H., & Yu, C. (2017). Dendritic mesoporous silica-titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760.
    DOI Scopus17 WoS14
    2017 Yang, Y., Jambhrunkar, M., Abbaraju, P. L., Yu, M., Zhang, M., & Yu, C. (2017). Understanding the Effect of Surface Chemistry of Mesoporous Silica Nanorods on Their Vaccine Adjuvant Potency. Advanced Healthcare Materials, 6(17), 12 pages.
    DOI Scopus40 WoS34 Europe PMC16
    2017 Song, H., Yu, M., Lu, Y., Gu, Z., Yang, Y., Zhang, M., . . . Yu, C. (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139(50), 18247-18254.
    DOI Scopus124 WoS88 Europe PMC43
    2017 Yang, Y., Lu, Y., Abbaraju, P. L., Zhang, J., Zhang, M., Xiang, G., & Yu, C. (2017). Multi-shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy. Angewandte Chemie - International Edition, 56(29), 8446-8450.
    DOI Scopus137 WoS114 Europe PMC42
    2017 Purwajanti, S., Huang, X., Liu, Y., Yang, Y., Noonan, O., Song, H., . . . Yu, C. (2017). Mg(OH)<inf>2</inf>-MgO@reduced graphene oxide nanocomposites: The roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry A, 5(46), 24484-24492.
    DOI Scopus25 WoS22
    2017 Abbaraju, P. L., Yang, Y., Yu, M., Fu, J., Xu, C., & Yu, C. (2017). Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery. Chemistry - An Asian Journal, 12(13), 1465-1469.
    DOI Scopus24 WoS18 Europe PMC5
    2017 Jiao, J., Fu, J., Wei, Y., Zhao, Z., Duan, A., Xu, C., . . . Liu, Y. (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal–support interaction. Journal of Catalysis, 356, 269-282.
    DOI Scopus98 WoS65
    2016 Wang, Y., Nor, Y. A., Song, H., Yang, Y., Xu, C., Yu, M., & Yu, C. (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4(15), 2646-2653.
    DOI Scopus93 WoS76 Europe PMC28
    2016 Purwajanti, S., Zhang, H., Huang, X., Song, H., Yang, Y., Zhang, J., . . . Yu, C. (2016). Mesoporous Magnesium Oxide Hollow Spheres as Superior Arsenite Adsorbent: Synthesis and Adsorption Behavior. ACS Applied Materials and Interfaces, 8(38), 25306-25312.
    DOI Scopus79 WoS64 Europe PMC13
    2016 Liu, Y., Zhang, H., Noonan, O., Xu, C., Niu, Y., Yang, Y., . . . Yu, C. (2016). Kinetically Controlled Assembly of Nitrogen-Doped Invaginated Carbon Nanospheres with Tunable Mesopores. Chemistry - A European Journal, 22(42), 14962-14967.
    DOI Scopus23 WoS18 Europe PMC4
    2016 Yang, Y., & Yu, C. (2016). Advances in silica based nanoparticles for targeted cancer therapy. Nanomedicine: Nanotechnology, Biology, and Medicine, 12(2), 317-332.
    DOI Scopus166 WoS123 Europe PMC69
    2016 Yu, M., Niu, Y., Zhang, J., Zhang, H., Yang, Y., Taran, E., . . . Yu, C. (2016). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9(2), 291-305.
    DOI Scopus36 WoS30
    2016 Yang, Y., Bernardi, S., Song, H., Zhang, J., Yu, M., Reid, J. C., . . . Yu, C. (2016). Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient. Chemistry of Materials, 28(3), 704-707.
    DOI Scopus214 WoS166
    2016 Hartono, S. B., Hadisoewignyo, L., Yang, Y., Meka, A. K., Antaresti., & Yu, C. (2016). Amine functionalized cubic mesoporous silica nanoparticles as an oral delivery system for curcumin bioavailability enhancement. NANOTECHNOLOGY, 27(50), 7 pages.
    DOI WoS40 Europe PMC19
    2016 Song, H., Ahmad Nor, Y., Yu, M., Yang, Y., Zhang, J., Zhang, H., . . . Yu, C. (2016). Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition. Journal of the American Chemical Society, 138(20), 6455-6462.
    DOI Scopus252 WoS193 Europe PMC78
    2016 Yang, Y., Wan, J., Niu, Y., Gu, Z., Zhang, J., Yu, M., & Yu, C. (2016). Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery. Chemistry of Materials, 28(24), 9008-9016.
    DOI Scopus152 WoS123
    2016 Zhang, H., Noonan, O., Huang, X., Yang, Y., Xu, C., Zhou, L., & Yu, C. (2016). Surfactant-Free Assembly of Mesoporous Carbon Hollow Spheres with Large Tunable Pore Sizes. ACS Nano, 10(4), 4579-4586.
    DOI Scopus434 WoS346 Europe PMC77
    2015 Zhang, H., Yu, M., Song, H., Noonan, O., Zhang, J., Yang, Y., . . . Yu, C. (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27(18), 6297-6304.
    DOI Scopus105 WoS92
    2015 Niu, Y., Yu, M., Meka, A., Liu, Y., Zhang, J., Yang, Y., & Yu, C. (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4(2), 212-219.
    DOI Scopus79 WoS67 Europe PMC31
    2015 Yang, Y., Yu, M., Song, H., Wang, Y., & Yu, C. (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7(28), 11894-11898.
    DOI Scopus27 WoS23 Europe PMC11
    2015 Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., . . . Yu, C. (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955.
    DOI Scopus157 WoS123 Europe PMC53
    2015 Yang, Y., Niu, Y., Zhang, J., Meka, A. K., Zhang, H., Xu, C., . . . Yu, C. (2015). Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery. Small, 11(23), 2743-2749.
    DOI Scopus78 WoS75 Europe PMC34
    2015 Niu, Y., Yu, M., Zhang, J., Yang, Y., Xu, C., Yeh, M., . . . Yu, C. (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3(43), 8477-8485.
    DOI Scopus40 WoS34 Europe PMC12
    2014 Yu, M., Karmakar, S., Yang, J., Zhang, H., Yang, Y., Thorn, P., & Yu, C. (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids. Chemical Communications, 50(13), 1527-1529.
    DOI Scopus15 WoS17 Europe PMC6
    2014 Yu, M., Niu, Y., Yang, Y., Hartono, S. B., Yang, J., Huang, X., . . . Yu, C. (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6(18), 15626-15631.
    DOI Scopus19 WoS18 Europe PMC6
    2014 Yang, Y., Karmakar, S., Yu, M., Popat, A., & Yu, C. (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, 43(3), 316-318.
    DOI Scopus2 WoS2
    2014 Yang, Y., Karmakar, S., Zhang, J., Yu, M., Mitter, N., & Yu, C. (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2(30), 4929-4934.
    DOI Scopus25 WoS21 Europe PMC8
    2014 Zhang, J., Raphael, A. P., Yang, Y., Popat, A., Prow, T. W., & Yu, C. (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of Materials Chemistry B, 2(44), 7673-7678.
    DOI Scopus16 WoS14 Europe PMC2
    2012 Jozwiak, M., Bloemenkamp, K. W. M., Kelly, A. J., Mol, B. W. J., Irion, O., & Boulvain, M. (2012). Mechanical Methods for Induction of Labor. BAHRAIN MEDICAL BULLETIN, 34(2), 2 pages.
    2009 Glaser, M., & Robins, E. G. (2009). 'Click labelling' in PET radiochemistry. Journal of Labelled Compounds and Radiopharmaceuticals, 52(10), 407-414.
    DOI Scopus88

  • Theses
    Year Citation
    - Yang, Y. (n.d.). Development of a mesoporous silica based nanosystem for safe and efficient therapeutic delivery.
  • NHMRC Emerging Leadership Fellow (EL1), 2022-2026, Sole CI, $650,740
  • ARC Discovery Project 2020-2023, CI B, $395,000
  • UQ-Early Career Researcher Grant 2020.1-2020.12, Sole CI, $20,000
  • Position: Group Leader, Biomat & Immune Eng Lab (BIEL)
  • Phone: 83133776
  • Email: yannan.yang@adelaide.edu.au
  • Campus: West End Health Precinct
  • Building: AHMS - Adelaide Health and Medical Sciences, floor Ninth Floor
  • Room: 9069
  • Org Unit: South Australian Immunogenomics Cancer Institute
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