Research Interests
Biomaterials Biomedical Engineering Tumour Immunology Nanobiotechnology Immunology and InfectionDr Yannan Yang
Group Leader
SAIGENCI
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Yannan Yang completed PhD (Biomedical Engineering) in Australian Institute of Bioengineering and Nanotechnology/University of Queensland in 2019 before taking a postdoctoral research follow position in the same institute. In 2023, he established his own research group (Biomaterials and Immune Engineering Laboratory - BIEL) in SAiGENCI in the University of Adelaide. He has developed innovative synthetic approaches for biomaterials and nanoparticles with controllable architecture and composition, and demonstrated the great potential of materials based cancer immunotherapy. Dr Yang's vision is to develop novel biomaterials-enabled vaccine technology for cancer immunotherapy and promote the clinic translation of the technology to significantly improve the treatment outcome of cancers with poor prognosis.
Dr Yannan Yang is the head of Biomaterials and Immune Engineering Laboratory (BIEL). BIEL aims to leverage state-of-the-art biomaterials and nanotechnology-based approaches to modulate immune system and create translational immunotherapy strategies with improved therapeutic efficacy and minimized adverse effects. Our laboratory is specifically interested in designing and fabricating biocompatible nanoparticles, hydrogels, scaffolds and cell/bacteria derived biomimetic materials with immunomodulatory activities and controlled drug release profile for engineering immunity. We stand at the materials-bio interface and investigate how biomaterials at different scales (nano, micro and bulk) can interact with bio-systems and tumour microenvironment, and how these interactions can be further controlled to benefit the outcome of immunotherapy that aims to prevent and treat cancer.
| Date | Position | Institution name |
|---|---|---|
| 2023 - ongoing | Group Leader | University of Adelaide |
| 2022 - 2023 | NHMRC Emerging Leadership Fellow | University of Queensland |
| 2019 - 2021 | Postdoctoral research fellow | University of Queensland |
| Date | Institution name | Country | Title |
|---|---|---|---|
| University of Queensland | Australia | PhD | |
| University of Queensland | Australia | MPhil | |
| Wuhan University | China | Bachelor |
| Year | Citation |
|---|---|
| 2026 | Dai, Z., Wang, Q., Zhang, M., Shi, Y., Yang, Y., Song, H., . . . Yu, C. (2026). Tumor-activated nanocomplex reprograms cancer and macrophage metabolism in opposite directions to overcome immune suppression. Biomaterials, 326, 123655. Scopus4 WoS3 Europe PMC2 |
| 2026 | Zou, J., Meng, G., Huang, Y., Huo, J., Yuan, H., Ma, H., . . . Yang, Y. (2026). An intermediate-crystalline phase manganese nanoadjuvant potently activates cGAS-STING signaling and antitumor immunity via immunometabolism normalization. Biomaterials, 328, 123901-1-123901-17. Scopus4 WoS3 |
| 2026 | Li, J., Zhang, Y., Wang, W., Gong, Y., Zhou, Y., & Yang, Y. (2026). Dual-Powered Nanomotor In Situ Vaccine with Tumor-Confined Penetration and Acidity Neutralization Boosts Stimulator of Interferon Genes-Mediated Immunotherapy.. ACS Nano, 20(2), 2018-2033. Scopus1 WoS1 |
| 2026 | Gong, Y., Yao, Y., Ruan, Z., Mei, N., Luo, D., Liu, X., . . . Ling, Y. (2026). A macrocyclic gadolinium contrast agent bearing an assembly-dissociable feature with albumin for enhanced magnetic resonance imaging and in vivo profiles. Journal of Materials Chemistry B, 14(8), 2495-2505. |
| 2026 | Hou, Y., Shi, Y., & Yang, Y. (2026). Immunomodulatory microbials for cancer immunotherapy: A mini review. Chinese Chemical Letters, 112912. |
| 2026 | Wu, T., Wang, F. -Y., Li, J., Zhong, W., Zhang, Y., Wang, W., . . . Yang, Y. (2026). A Skin and Tumor Dual-Permeable Tumoricidal Gel for cGAS-STING Activation-Enhanced Chemoimmunotherapy. ACS Nano, 20(28), 20090-20106. |
| 2026 | Wang, W., Gong, Y., Li, J., Wu, T., Deng, M., & Yang, Y. (2026). A Glucose Metabolism-Modulatory Nanobiohybrid Vaccine Platform Promotes Anti-Tumor Immunity by Orchestrating Autophagy-Dependent Cross-Presentation and H₂S-Enhanced NLRP3 Inflammasome Signaling. Advanced Science, e76654-1-e76654-18. |
| 2026 | Zhao, X., Hu, Z., Xu, Q., Zou, J., Huo, J., Yang, Y., . . . Zhang, M. (2026). A genetically engineered biomimetic nanomedicine with radio-taxis and CD47 blockade for precision tumor radio-immunotherapy. Chemical Engineering Journal, 545, 17 pages. |
| 2025 | Gong, Y., Zhang, H., Lu, M., Sun, J., Jia, Y., Yang, Y., . . . Ling, Y. (2025). Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications. Journal of Colloid and Interface Science, 679(Pt B), 412-421. Scopus7 WoS7 Europe PMC2 |
| 2025 | Luo, D., Wu, T., Qiu, T., Li, J., Gong, Y., Weng, J., . . . Zhou, Y. (2025). Coordination-Dissociation Induced T<inf>1</inf>-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring. Advanced Functional Materials, 35(33). Scopus7 |
| 2025 | Wu, T., Chen, Y., Gong, Y., Lu, M., Yang, C., Yang, Y., . . . Zhou, Y. (2025). A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells. Molecules, 30(11), 17 pages. Scopus2 WoS2 Europe PMC2 |
| 2025 | Shi, Y., Hou, Y., Mabrouk, M. T., Yu, C., & Yang, Y. (2025). In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation.. Adv Sci (Weinh), 12(37), e09836. Scopus10 WoS9 Europe PMC4 |
| 2025 | Liu, X., Wang, W., Wu, T., Li, J., Gong, Y., Luo, D., . . . Yang, Y. (2025). Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy. ACS Applied Materials & Interfaces, 17(36), 50548-50559. |
| 2025 | Luo, J., Wang, Y., Dai, Z., Shi, Y., Wu, W., Qu, J., . . . Yang, Y. (2025). Passivation-Engineered Zinc Peroxide Nanoparticles as Th1-Biased Adjuvant for Antitumor Immunity. Small, 21(42), e05250-1-e05250-14. Scopus1 WoS1 Europe PMC2 |
| 2025 | Luo, J., Wang, Y., Yu, C., & Yang, Y. (2025). Bimetallic nanoadjuvants for cancer vaccines.. Trends Pharmacol Sci, 46(10), 958-974. Scopus2 WoS3 Europe PMC1 |
| 2025 | Wu, W., Guo, F., Wang, C., Qu, X., Wang, Q., Yang, Y., . . . Ma, Y. (2025). Biomimetic “Trojan Horse” nanoparticles with biotactic behavior toward tumor-associated bacteria for targeted therapy of colorectal cancer. Cell Biomaterials, 1(6), 100092. Scopus19 |
| 2024 | Zhang, Y., Yu, Y., Yang, Y., Wang, Y., & Yu, C. (2024). Engineered Silica Nanoparticles for Nucleic Acid Delivery. Small Methods, 8(3), 2300812-1-2300812-16. Scopus11 WoS8 Europe PMC5 |
| 2024 | Yang, Y., Chen, S., Zhang, M., Shi, Y., Luo, J., Huang, Y., . . . Yu, C. (2024). Mesoporous nanoperforators as membranolytic agents via nano- and molecular-scale multi-patterning.. Nat Commun, 15(1), 1891. Scopus10 WoS10 Europe PMC6 |
| 2024 | Zhang, M., Lu, M., Gong, Y., Yang, Y., Song, J., Li, J., . . . Zhou, Y. (2024). Tadpole-Like Carbon Nanotube with Fe Nanoparticle Encapsulated at the Head and Zn Single-Atom Anchored on the Body: One-Pot Carbonization for Tetramodal Synergistic Cancer Therapy. Small, 20(40), e2400587. Scopus6 WoS6 Europe PMC5 |
| 2024 | Huang, Y., Zou, J., Huo, J., Zhang, M., & Yang, Y. (2024). Sulfate Radical Based In Situ Vaccine Boosts Systemic Antitumor Immunity via Concurrent Activation of Necroptosis and STING Pathway. Advanced Materials, 36(41), e2407914-1-e2407914-15. Scopus40 WoS38 Europe PMC16 |
| 2024 | Zhang, Y., Yao, Y., Xie, F., Hu, W. L., Zou, Y., Zhao, Q., . . . Yu, C. (2024). Iron consumption strengthens anti-tumoral STING activation mediated by manganese-based nanoparticles. Nano Today, 58, 102446. Scopus11 WoS10 |
| 2024 | Huo, J., Zou, J., Ma, H., Meng, G., Huang, Y., Yan, X., . . . Zhang, M. (2024). Astragaloside IV microfibers assembling into injectable 3D-scaffolds with intrinsic immunoactivity for enhanced tumor vaccine efficacy. Chemical Engineering Journal, 498, 155511-1-155511-13. Scopus4 WoS3 |
| 2024 | Lu, W., Wang, W., Gong, Y., Li, J., Zhou, Y., & Yang, Y. (2024). A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis.. Small, 20(49), 2407676-1-2407676-12. Scopus12 WoS12 Europe PMC5 |
| 2024 | Jin, Y., Hu, C., Xia, J., Xie, D., Ye, L., Ye, X., . . . Hu, Z. (2024). Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization. Bioactive Materials, 42, 613-627. Scopus17 WoS18 Europe PMC5 |
| 2024 | Li, J., Wu, T., Wang, W., Gong, Y., Lu, M., Zhang, M., . . . Yang, Y. (2024). Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines. Science Advances, 10(38), eadn3002-1-eadn3002-15. Scopus30 WoS27 Europe PMC19 |
| 2023 | Zhang, M., Huang, Y., Zou, J., Yang, Y., Yao, Y., Cheng, G., & Yang, Y. (2023). Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Advanced Science, 10(22), 10 pages. Scopus19 WoS11 Europe PMC11 |
| 2023 | Li, J., Lu, W., Yang, Y., Xiang, R., Ling, Y., Yu, C., & Zhou, Y. (2023). Hybrid Nanomaterials for Cancer Immunotherapy. Advanced Science, 10(6), 42 pages. Scopus129 WoS120 Europe PMC70 |
| 2023 | Zhang, M., Wu, T., Zhang, H., Chen, Z., Yang, Y., Ling, Y., & Zhou, Y. (2023). Mesoporous carbon hemispheres integrated with Fe-Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy. Journal of Materials Chemistry B, 12(3), 9 pages. Scopus8 WoS8 Europe PMC3 |
| 2023 | Shi, Y., Dai, Z., Wang, Y., Luo, J., Cai, L., Tang, J., . . . Yang, Y. (2023). Engineering Crystallinity Gradients for Tailored CaO₂ Nanostructures: Enabling Alkalinity-Reinforced Anticancer Activity with Minimized Ca²⁺/H₂O₂ Production. Nano letters, 23(23), 10657-10666. Scopus9 WoS9 Europe PMC3 |
| 2023 | Zhang, M., Lu, M., Qiu, T., Wang, Q., Chen, Z., Deng, M., . . . Zhou, Y. (2023). Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications. Small, 19(34), e2301894. Scopus31 Europe PMC9 |
| 2022 | Dai, Z., Wang, Q., Tang, J., Qu, R., Wu, M., Li, H., . . . Yu, C. (2022). A Sub-6 nm MnFe<inf>2</inf>O<inf>4</inf>-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy. Biomaterials, 284, 11 pages. Scopus50 WoS49 Europe PMC34 |
| 2022 | Dai, Z., Wang, Q., Tang, J., Wu, M., Li, H., Yang, Y., . . . Yu, C. (2022). Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy. Biomaterials, 280, 121261-1-121261-13. Scopus69 WoS63 Europe PMC39 |
| 2022 | Zhao, L., Zhang, Y., Yang, Y., & Yu, C. (2022). Silica-based Nanoparticles for Enzyme Immobilization and Delivery. Chemistry - An Asian Journal, 17(17), 1-9. Scopus35 WoS34 Europe PMC15 |
| 2022 | Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., . . . Yu, C. (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 1-8. Scopus36 WoS37 Europe PMC17 |
| 2022 | Wang, F. Y., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie - International Edition, 61(41), 12 pages. Scopus12 WoS15 Europe PMC7 |
| 2022 | Theivendran, S., Gu, Z., Tang, J., Yang, Y., Song, H., Yang, Y., . . . Yu, C. (2022). Nanostructured Organosilica Nitric Oxide Donors Intrinsically Regulate Macrophage Polarization with Antitumor Effect. ACS Nano, 16(7), 10943-10957. Scopus80 WoS81 Europe PMC53 |
| 2022 | Yu, Z., Fang, W., Yang, Y., Yao, H., Hu, P., & Shi, J. (2022). Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an Example. Advanced Healthcare Materials, 11(17), 9 pages. Scopus5 WoS5 Europe PMC3 |
| 2022 | Zhang, M., Feng, J., Zhong, Y., Luo, J., Zhao, Y., Yang, Y., . . . Yu, C. (2022). In-situ synthesis of Drug-Containing bactericidal rough silica nanoparticles for antibacterial coating. Chemical Engineering Journal, 440, 1-11. Scopus23 WoS22 |
| 2022 | Wang, F., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie, 134(41), e202209499-1-e202209499-12. |
| 2022 | Tang, J., Yang, Y., Qu, J., Ban, W., Song, H., Gu, Z., . . . Yu, C. (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13(29), 8507-8517. Scopus23 WoS23 Europe PMC19 |
| 2022 | Kothalawala, S. G., Jiao, J., Speight, R., Song, H., Yang, Y., & Zhang, J. (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338, 1-9. Scopus31 WoS29 |
| 2021 | Zhang, M., Dai, Z., Theivendran, S., Gu, Z., Zhao, L., Song, H., . . . Yu, C. (2021). Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy. Nano Today, 36, 18 pages. Scopus33 WoS32 |
| 2021 | Luo, J., Zhang, M., Yang, Y., & Yu, C. (2021). Synthesis of dendritic mesoporous organosilica nanoparticles under a mild acidic condition with homogeneous wall structure and near-neutral surface. Chemical Communications, 57(36), 4416-4419. Scopus7 WoS6 Europe PMC3 |
| 2021 | Fu, J., Jiao, J., Ban, W., Kong, Y., Gu, Z., Song, H., . . . Yu, C. (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417, 1-7. Scopus20 WoS18 |
| 2021 | Lin, X., Wu, W., Fu, J., Yang, Y., Guo, B., Yu, C., & Song, H. (2021). Asymmetric Silica Nanoparticles with Tailored Spiky Coverage Derived from Silica-Polymer Cooperative Assembly for Enhanced Hemocompatibility and Gene Delivery. ACS Applied Materials and Interfaces, 13(43), 50695-50704. Scopus21 WoS19 Europe PMC10 |
| 2021 | Yang, Y., Zhang, M., Yang, Y., Cheng, D., & Yu, C. (2021). Designer Anticancer Nanoprodrugs with Self-Toxification Activity Realized by Acid-triggered Biodegradation and In Situ Fragment Complexation. Angewandte Chemie - International Edition, 60(20), 11504-11513. Scopus13 WoS14 Europe PMC6 |
| 2021 | Gu, Z., Liu, T., Liu, C., Yang, Y., Tang, J., Song, H., . . . Yu, C. (2021). Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities. Nano Letters, 21(15), 6471-6479. Scopus122 WoS119 Europe PMC106 |
| 2021 | Song, Y., Cheng, D., Luo, J., Zhang, M., & Yang, Y. (2021). Surfactant-free synthesis of monodispersed organosilica particles with pure sulfide-bridged silsesquioxane framework chemistry via extension of Stöber method. Journal of Colloid and Interface Science, 591, 129-138. Scopus15 WoS12 Europe PMC8 |
| 2021 | Wang, Y., Song, H., Liu, C., Zhang, Y., Kong, Y., Tang, J., . . . Yu, C. (2021). Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bioregulators for enhanced mRNa delivery in vivo. National Science Review, 8(8), 10 pages. Scopus47 WoS99 Europe PMC27 |
| 2021 | Yang, Y., Gu, Z., Tang, J., Zhang, M., Yang, Y., Song, H., & Yu, C. (2021). MnO<inf>2</inf> Nanoflowers Induce Immunogenic Cell Death under Nutrient Deprivation: Enabling an Orchestrated Cancer Starvation-Immunotherapy. Advanced Science, 8(4), 1-10. Scopus62 WoS61 |
| 2020 | Dai, Z., Tang, J., Gu, Z., Wang, Y., Yang, Y., Yang, Y., & Yu, C. (2020). Eliciting Immunogenic Cell Death via a Unitized Nanoinducer. Nano Letters, 20(9), 6246-6254. Scopus115 WoS113 Europe PMC87 |
| 2020 | Wang, Y., Tang, J., Yang, Y., Song, H., Fu, J., Gu, Z., & Yu, C. (2020). Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells. Angewandte Chemie - International Edition, 59(7), 2695-2699. Scopus66 WoS65 Europe PMC45 |
| 2020 | Yang, Y., Zhang, M., Song, H., & Yu, C. (2020). Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators. Accounts of Chemical Research, 53(8), 1545-1556. Scopus228 WoS198 Europe PMC114 |
| 2020 | Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., . . . Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430. Scopus17 WoS16 Europe PMC17 |
| 2020 | Jambhrunkar, M., Yang, Y., Yu, M., Zhang, M., Abbaraju, P. L., Ghosh, T., . . . Yu, C. (2020). Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity. Materials Today Advances, 6, 8 pages. Scopus27 WoS27 |
| 2020 | Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie, 132(27), 10923-10927. |
| 2020 | Shi, Y., Fu, J., & Yang, Y. (2020). Effects of synthetic routes on the compositional and structural properties of dendritic mesoporous organosilica nanoparticles: The unexpected reversed “double-edged sword” role of reaction time. Microporous and Mesoporous Materials, 294, 1-8. Scopus6 WoS5 |
| 2020 | Song, H., Yang, Y., Tang, J., Gu, Z., Wang, Y., Zhang, M., & Yu, C. (2020). DNA Vaccine Mediated by Rambutan-Like Mesoporous Silica Nanoparticles. Advanced Therapeutics, 3(1), 12 pages. Scopus26 WoS23 |
| 2020 | Geng, J., Song, H., Gao, F., Kong, Y., Fu, J., Luo, J., . . . Yu, C. (2020). Lyophilization enabled disentanglement of polyethylenimine on rambutan-like silica nanoparticles for enhanced plasmid DNA delivery. Journal of Materials Chemistry B, 8(21), 4593-4600. Scopus7 WoS7 Europe PMC7 |
| 2020 | Liu, Y., Kong, Y., Kumar Nanjundan, A., Yang, Y., Zhou, L., Huang, X., & Yu, C. (2020). Modulating the Void Space of Nitrogen-Doped Hollow Mesoporous Carbon Spheres for Lithium-Sulfur Batteries. ChemNanoMat, 6(6), 925-929. Scopus7 WoS7 |
| 2020 | Tang, J., Meka, A. K., Theivendran, S., Wang, Y., Yang, Y., Song, H., . . . Yu, C. (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062. Scopus130 WoS133 Europe PMC92 |
| 2020 | Wang, Y., Yang, Y., Shi, Y., Song, H., & Yu, C. (2020). Antibiotic-Free Antibacterial Strategies Enabled by Nanomaterials: Progress and Perspectives. Advanced Materials, 32(18), 1-21. Scopus773 WoS758 Europe PMC336 |
| 2020 | Yang, Y., Tang, J., Song, H., Yang, Y., Gu, Z., Fu, J., . . . Yu, C. (2020). Dendritic Mesoporous Silica Nanoparticle Adjuvants Modified with Binuclear Aluminum Complex: Coordination Chemistry Dictates Adjuvanticity. Angewandte Chemie - International Edition, 59(44), 19610-19617. Scopus45 WoS44 Europe PMC18 |
| 2020 | Zhang, M., Yang, Y., Liu, Y., Fu, J., Lu, J., Yang, Y., . . . Yu, C. (2020). 3D-Nanosponge enabled segregation: A versatile approach for highly dispersed and high content functionalization of metal oxide species. Materials Chemistry Frontiers, 4(6), 1739-1746. Scopus4 WoS3 |
| 2020 | Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie - International Edition, 59(27), 10831-10835. Scopus143 WoS141 Europe PMC88 |
| 2019 | Gu, Z., Liu, T., Tang, J., Yang, Y., Song, H., Tuong, Z. K., . . . Yu, C. (2019). Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway. Journal of the American Chemical Society, 141(15), 6122-6126. Scopus184 WoS173 Europe PMC126 |
| 2019 | Theivendran, S., Zhang, J., Tang, C., Kalantari, M., Gu, Z., Yang, Y., . . . Yu, C. (2019). Synthesis of biphenyl bridged dendritic mesoporous organosilica with extremely high adsorption of pyrene. Journal of Materials Chemistry A, 7(19), 12029-12037. Scopus26 WoS25 |
| 2019 | Yang, Y., Tang, J., Zhang, M., Gu, Z., Song, H., Yang, Y., & Yu, C. (2019). Responsively Aggregatable Sub-6 nm Nanochelators Induce Simultaneous Antiangiogenesis and Vascular Obstruction for Enhanced Tumor Vasculature Targeted Therapy. Nano Letters, 19(11), 7750-7759. Scopus43 WoS36 Europe PMC27 |
| 2019 | Song, H., Yang, Y., Geng, J., Gu, Z., Zou, J., & Yu, C. (2019). Electron Tomography: A Unique Tool Solving Intricate Hollow Nanostructures. Advanced Materials, 31(38), 1801564. Scopus47 WoS47 Europe PMC22 |
| 2019 | Fu, J., Gu, Z., Liu, Y., Zhang, J., Song, H., Yang, Y., . . . Yu, C. (2019). Bottom-up self-assembly of heterotrimeric nanoparticles and their secondary Janus generations. Chemical Science, 10(44), 10388-10394. Scopus38 WoS34 Europe PMC12 |
| 2018 | Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., & Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019. Scopus7 WoS8 Europe PMC5 |
| 2018 | Yang, Y., Lu, Y., Abbaraju, P. L., Azimi, I., Lei, C., Tang, J., . . . Yu, C. (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1-11. Scopus119 WoS113 |
| 2018 | Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off‐the‐Shelf Strategy for Concurrently Enhanced Chemo‐immunotherapy. Angewandte Chemie, 130(36), 11938-11943. |
| 2018 | Zhang, M., Yang, Y., & Yu, C. (2018). Nano-resoles-Enabled Elegant Nanostructured Materials. Chemistry A European Journal, 24(55), 14598-14607. Scopus8 WoS7 Europe PMC1 |
| 2018 | Lu, Y., Yang, Y., Gu, Z., Zhang, J., Song, H., Xiang, G., & Yu, C. (2018). Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy. Biomaterials, 175, 82-92. Scopus167 WoS155 Europe PMC109 |
| 2018 | Liu, C., Huang, X., Wang, J., Song, H., Yang, Y., Liu, Y., . . . Yu, C. (2018). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28(6), 1-8. Scopus144 WoS132 |
| 2018 | Kalantari, M., Yu, M., Jambhrunkar, M., Liu, Y., Yang, Y., Huang, X., & Yu, C. (2018). Designed synthesis of organosilica nanoparticles for enzymatic biodiesel production. Materials chemistry frontiers, 2(7), 1334-1342. Scopus32 WoS30 |
| 2018 | Abbaraju, P. L., Jambhrunkar, M., Yang, Y., Liu, Y., Lu, Y., & Yu, C. (2018). Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses. Chemical communications, 54(16), 2020-2023. Scopus54 WoS48 Europe PMC33 |
| 2018 | Zhang, M., Song, H., Yang, Y., Huang, X., Liu, Y., Liu, C., & Yu, C. (2018). Oxidative Dissolution of Resoles: A Versatile Approach to Intricate Nanostructures. Angewandte Chemie International Edition, 57(3), 654-658. Scopus17 WoS16 Europe PMC11 |
| 2018 | Kalantari, M., Liu, Y., Strounina, E., Yang, Y., Song, H., & Yu, C. (2018). Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties. Journal of Materials Chemistry A, 6(36), 17579-17586. Scopus23 WoS21 |
| 2018 | Wang, Y., Song, H., Yu, M., Xu, C., Liu, Y., Tang, J., . . . Yu, C. (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6(24), 4089-4095. Scopus81 WoS76 Europe PMC49 |
| 2018 | Wang, Y., Song, H., Yang, Y., Liu, Y., Tang, J., & Yu, C. (2018). Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling. Chemistry of Materials, 30(16), 5770-5776. Scopus55 WoS54 |
| 2018 | Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769. Scopus112 WoS114 Europe PMC80 |
| 2018 | Pan, D., Chen, W., Huang, X., Zhang, J., Yang, Y., Yu, F., . . . Yu, C. (2018). Solvothermal-assisted evaporation-induced self-assembly of ordered mesoporous alumina with improved performance. Journal of Colloid and Interface Science, 529, 432-443. Scopus25 WoS22 Europe PMC6 |
| 2017 | Song, H., Yu, M., Lu, Y., Gu, Z., Yang, Y., Zhang, M., . . . Yu, C. (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139(50), 18247-18254. Scopus138 WoS126 Europe PMC90 |
| 2017 | Yang, Y., Lu, Y., Abbaraju, P. L., Zhang, J., Zhang, M., Xiang, G., & Yu, C. (2017). Multi-shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy. Angewandte Chemie International Edition, 56(29), 8446-8450. Scopus147 WoS151 Europe PMC81 |
| 2017 | Yang, Y., Jambhrunkar, M., Abbaraju, P. L., Yu, M., Zhang, M., & Yu, C. (2017). Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency. Advanced healthcare materials, 6(17, article no. 1700466), 1-12. Scopus42 WoS44 Europe PMC31 |
| 2017 | Lin, C. X. C., Xu, C., Yang, Y., Lei, C., Zhang, H., & Yu, C. (2017). Dendritic mesoporous silica-titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760. Scopus18 WoS17 |
| 2017 | Purwajanti, S., Huang, X., Liu, Y., Yang, Y., Noonan, O., Song, H., . . . Yu, C. (2017). Mg(OH)2-MgO@reduced graphene oxide nanocomposites: The roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry A, 5(46), 24484-24492. Scopus31 WoS28 |
| 2017 | Abbaraju, P. L., Yang, Y., Yu, M., Fu, J., Xu, C., & Yu, C. (2017). Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery. Chemistry an Asian Journal, 12(13), 1465-1469. Scopus24 WoS20 Europe PMC9 |
| 2017 | Jiao, J., Fu, J., Wei, Y., Zhao, Z., Duan, A., Xu, C., . . . Liu, Y. (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal–support interaction. Journal of Catalysis, 356, 269-282. Scopus112 WoS107 |
| 2017 | Kalantari, M., Yu, M., Yang, Y., Strounina, E., Gu, Z., Huang, X., . . . Yu, C. (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10(2), 605-617. Scopus76 WoS72 |
| 2017 | Abbaraju, P. L., Meka, A. K., Song, H., Yang, Y., Jambhrunkar, M., Zhang, J., . . . Yu, C. (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American chemical society, 139(18), 6321-6328. Scopus134 WoS132 Europe PMC76 |
| 2016 | Yang, Y., Bernardi, S., Song, H., Zhang, J., Yu, M., Reid, J. C., . . . Yu, C. (2016). Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient. Chemistry of Materials, 28(3), 704-707. Scopus243 WoS237 |
| 2016 | Hartono, S. B., Hadisoewignyo, L., Yang, Y., Meka, A. K., Antaresti., & Yu, C. (2016). Amine functionalized cubic mesoporous silica nanoparticles as an oral delivery system for curcumin bioavailability enhancement. NANOTECHNOLOGY, 27(50), 7 pages. WoS52 Europe PMC28 |
| 2016 | Song, H., Ahmad Nor, Y., Yu, M., Yang, Y., Zhang, J., Zhang, H., . . . Yu, C. (2016). Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition. Journal of the American Chemical Society, 138(20), 6455-6462. Scopus279 WoS267 Europe PMC158 |
| 2016 | Yang, Y., Wan, J., Niu, Y., Gu, Z., Zhang, J., Yu, M., & Yu, C. (2016). Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery. Chemistry of Materials, 28(24), 9008-9016. Scopus167 WoS164 |
| 2016 | Yang, Y., & Yu, C. (2016). Advances in silica based nanoparticles for targeted cancer therapy. Nanomedicine Nanotechnology Biology and Medicine, 12(2), 317-332. Scopus183 WoS149 Europe PMC100 |
| 2016 | Yu, M., Niu, Y., Zhang, J., Zhang, H., Yang, Y., Taran, E., . . . Yu, C. (2016). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9(2), 291-305. Scopus38 WoS37 |
| 2016 | Purwajanti, S., Zhang, H., Huang, X., Song, H., Yang, Y., Zhang, J., . . . Yu, C. (2016). Mesoporous Magnesium Oxide Hollow Spheres as Superior Arsenite Adsorbent: Synthesis and Adsorption Behavior. ACS Applied Materials and Interfaces, 8(38), 25306-25312. Scopus86 WoS78 Europe PMC25 |
| 2016 | Liu, Y., Zhang, H., Noonan, O., Xu, C., Niu, Y., Yang, Y., . . . Yu, C. (2016). Kinetically Controlled Assembly of Nitrogen-Doped Invaginated Carbon Nanospheres with Tunable Mesopores. Chemistry A European Journal, 22(42), 14962-14967. Scopus23 WoS22 Europe PMC7 |
| 2016 | Wang, Y., Nor, Y. A., Song, H., Yang, Y., Xu, C., Yu, M., & Yu, C. (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4(15), 2646-2653. Scopus106 WoS102 Europe PMC56 |
| 2016 | Zhang, H., Noonan, O., Huang, X., Yang, Y., Xu, C., Zhou, L., & Yu, C. (2016). Surfactant-Free Assembly of Mesoporous Carbon Hollow Spheres with Large Tunable Pore Sizes. ACS Nano, 10(4), 4579-4586. Scopus471 WoS458 Europe PMC144 |
| 2015 | Niu, Y., Yu, M., Meka, A., Liu, Y., Zhang, J., Yang, Y., & Yu, C. (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4(2), 212-219. Scopus88 WoS86 Europe PMC56 |
| 2015 | Zhang, H., Yu, M., Song, H., Noonan, O., Zhang, J., Yang, Y., . . . Yu, C. (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27(18), 6297-6304. Scopus111 WoS110 |
| 2015 | Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., . . . Yu, C. (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955. Scopus172 WoS165 Europe PMC107 |
| 2015 | Yang, Y., Niu, Y., Zhang, J., Meka, A. K., Zhang, H., Xu, C., . . . Yu, C. (2015). Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery. Small, 11(23), 2743-2749. Scopus81 WoS82 Europe PMC54 |
| 2015 | Yang, Y., Yu, M., Song, H., Wang, Y., & Yu, C. (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7(28), 11894-11898. Scopus27 WoS25 Europe PMC16 |
| 2015 | Niu, Y., Yu, M., Zhang, J., Yang, Y., Xu, C., Yeh, M., . . . Yu, C. (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3(43), 8477-8485. Scopus42 WoS40 Europe PMC25 |
| 2014 | Zhang, J., Raphael, A. P., Yang, Y., Popat, A., Prow, T. W., & Yu, C. (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of materials chemistry, 2(44), 7673-7678. Scopus17 WoS16 Europe PMC10 |
| 2014 | Yang, Y., Karmakar, S., Zhang, J., Yu, M., Mitter, N., & Yu, C. (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2(30), 4929-4934. Scopus25 WoS25 Europe PMC13 |
| 2014 | Yu, M., Niu, Y., Yang, Y., Hartono, S. B., Yang, J., Huang, X., . . . Yu, C. (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6(18), 15626-15631. Scopus20 WoS19 Europe PMC11 |
| 2014 | Yang, Y., Karmakar, S., Yu, M., Popat, A., & Yu, C. (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, 43(3), 316-318. Scopus2 WoS2 |
| 2014 | Yu, M., Karmakar, S., Yang, J., Zhang, H., Yang, Y., Thorn, P., & Yu, C. (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids. Chemical Communications, 50(13), 1527-1529. Scopus17 WoS19 Europe PMC11 |
| - | Ishikawa, U., Mabrouk, M. T., & Yang, Y. (2026). Intratumoral Delivery of mRNA for Cancer Immunotherapy: Progresses, Challenges, and Clinical Translation. ACS Nano Medicine. |
| Year | Citation |
|---|---|
| - | Yang, Y. (n.d.). Development of a mesoporous silica based nanosystem for safe and efficient therapeutic delivery. |
- NHMRC Emerging Leadership Fellow (EL1), 2022-2026, Sole CI, $650,740
- ARC Discovery Project 2020-2023, CI B, $395,000
- UQ-Early Career Researcher Grant 2020.1-2020.12, Sole CI, $20,000
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2026 | Principal Supervisor | Biomaterials Bridging Innate and Adaptive Immune Cells for Enhancing Cancer Immunotherapy | Doctor of Philosophy | Doctorate | Full Time | Ms An My Tran Le |
| 2025 | Principal Supervisor | Bioengineered Therapeutic Platforms for Cancer Immunotherapy | Doctor of Philosophy | Doctorate | Full Time | Miss Yuxuan Hou |
| 2024 | Principal Supervisor | Reprogramming Tumor-Associated Macrophages with mRNA Encapsulated Plant-Based Virus-like Nanoparticles for Immunotherapy of Triple Negative Breast Cancer | Master of Philosophy (Medical Science) | Master | Full Time | Miss Uta Ishikawa |
| 2024 | Principal Supervisor | Reprogramming Tumor-Associated Macrophages with mRNA Encapsulated Plant-Based Virus-like Nanoparticles for Immunotherapy of Triple Negative Breast Cancer | Master of Philosophy (Medical Science) | Master | Full Time | Miss Uta Ishikawa |
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