Yali Zhang

Yali Zhang

School of Chemical Engineering

Faculty of Sciences, Engineering and Technology

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


Emerging therapies are more likely to rely on the delivery of biological therapeutics to the cytosol. Nanoparticles (NPs) have shown significant potential for delivery and successfully entered clinical use. However, most nanoparticles taken up by endocytosis either accumulate in endosomes and lysosomes or are pumped out through exocytosis, where they are not active for therapeutic functions. Current studies on how to enhance endosomal escape and release are hampered by a lack of quantitative methodology to detect NP delivery efficiency. Dr Yali Zhang is a specialist in cellular and molecular biology with a focus on RNA, with expertise lies in unraveling the complex roles and regulatory mechanisms and driving innovative research and potential applications in RNA (AHM, IJMS, JCP, Biomedicines, etc.) She is now developing quantitative assays to probe endosomal escape and cytosolic delivery of NPs, which provides a better understanding of endocytosis pathways and is beneficial to nanomedicine engineering.

2018 Griffith University: Academic and lab demonstrator and assistant 

2021 University of South Australia: Academic and lab demonstrator and assistant  

2022 The University of Adelaide College/Kaplan: Academic teacher for biology 

2024 The University of Adelaide: invited lecturer for Fundamental Materials

  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2024 Co-Supervisor Development of Cancer-on-a-Chip Platforms for Drug Screening Doctor of Philosophy Doctorate Full Time Mr Max George Higham
  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2023 - 2023 Co-Supervisor Fighting Cancer with Space Nanomedicines The University of Adelaide - Master Full Time Isabel Elizabeth Lean

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