Dr Wai Low

• Appointments

  Date	Position	Institution name
  2017 - ongoing	Bioinformatics data scientist	University of Adelaide
  2014 - 2017	Assistant Professor	Perdana University

• Language Competencies

  Language	Competency
  Chinese (Cantonese)	Can speak and understand spoken
  English	Can read, write, speak, understand spoken and peer review
  Malay	Can read, write, speak, understand spoken and peer review

• Education

  Date	Institution name	Country	Title
  2017 - 2022	University of Adelaide	Australia	Post-graduate Diploma in Biostatistics
  2009 - 2009	University of Melbourne	Australia	PhD (Genetics)

• Research Interests

  Bioinformatics Biostatistics Genetics Genome Structure and Regulation Molecular Evolution

• Journals

  Year	Citation
  2022	Doan, P. T. K., Low, W. Y., Ren, Y., Tearle, R., & Hemmatzadeh, F. (2022). Newcastle disease virus genotype VII gene expression in experimentally infected birds.. Scientific reports, 12(1), 8 pages. DOI
  2022	Low, W. Y., Rosen, B. D., Ren, Y., Bickhart, D. M., To, T. -H., Martin, F. J., . . . Smith, T. P. L. (2022). Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle.. BMC genomics, 23(1), 15 pages. DOI Scopus1 WoS1
  2022	Alhamami, T., Low, W. Y., Ren, Y., Taylor, K., Khazandi, M., Veltman, T., . . . Trott, D. J. (2022). Antimicrobial susceptibility and genomic analysis of Histophilus somni isolated from cases of bovine respiratory disease in Autralian feedlot cattle. Veterinary Microbiology, 270, 9 pages. DOI
  2022	MacPhillamy, C., Alinejad-Rokny, H., Pitchford, W. S., & Low, W. Y. (2022). Cross-species enhancer prediction using machine learning. Genomics, 114(5), 12 pages. DOI
  2022	Messele, Y. E., Alkhallawi, M., Veltman, T., Trott, D. J., McMeniman, J. P., Kidd, S. P., . . . Petrovski, K. R. (2022). Phenotypic and Genotypic Analysis of Antimicrobial Resistance in Escherichia coli Recovered from Feedlot Beef Cattle in Australia. Animals, 12(17), 15 pages. DOI
  2022	Messele, Y. E., Hasoon, M. F., Trott, D. J., Veltman, T., McMeniman, J. P., Kidd, S. P., . . . Petrovski, K. R. (2022). Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit. Animals, 12(19), 18 pages. DOI
  2021	Abdel-Shafy, H., Deng, T., Zhou, Y., Low, W. Y., & Hua, G. (2021). Editorial: Buffalo Genetics and Genomics.. Front Genet, 12, 820627. DOI Scopus1 WoS1 Europe PMC1
  2021	Macciotta, N. P. P., Colli, L., Cesarani, A., Ajmone-Marsan, P., Low, W. Y., Tearle, R., & Williams, J. L. (2021). The distribution of runs of homozygosity in the genome of river and swamp buffaloes reveals a history of adaptation, migration and crossbred events.. Genet Sel Evol, 53(1), 1-21. DOI Scopus12 WoS12 Europe PMC7
  2021	Pineda, P. S., Flores, E. B., Herrera, J. R. V., & Low, W. Y. (2021). Opportunities and Challenges for Improving the Productivity of Swamp Buffaloes in Southeastern Asia.. Frontiers in genetics, 12, 629861. DOI Scopus5 WoS2 Europe PMC1
  2021	Kronenberg, Z. N., Rhie, A., Koren, S., Concepcion, G. T., Peluso, P., Munson, K. M., . . . Kingan, S. B. (2021). Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C.. Nature communications, 12(1), 1935. DOI Scopus25 WoS23 Europe PMC15
  2021	Stephenson, T., Speight, N., Low, W. Y., Woolford, L., Tearle, R., & Hemmatzadeh, F. (2021). Molecular Diagnosis of Koala Retrovirus (KoRV) in South Australian Koalas (Phascolarctos cinereus). Animals, 11(5), 1-13. DOI Scopus3 WoS3 Europe PMC2
  2021	Liu, R., Tearle, R., Low, W. Y., Chen, T., Thomsen, D., Smith, T. P. L., . . . Williams, J. L. (2021). Distinctive gene expression patterns and imprinting signatures revealed in reciprocal crosses between cattle sub-species. BMC Genomics, 22(1), 1-10. DOI Scopus2 Europe PMC1
  2021	Ren, Y., Macphillamy, C., To, T. -H., Smith, T. P. L., Williams, J. L., & Low, W. Y. (2021). Adaptive selection signatures in river buffalo with emphasis on immune and major histocompatibility complex genes.. Genomics, 113(6), 3599-3609. DOI Scopus4 WoS3 Europe PMC2
  2021	Liu, N., Low, W. Y., Alinejad-Rokny, H., Pederson, S., Sadlon, T., Barry, S., & Breen, J. (2021). Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C. Epigenetics & chromatin, 14(1), 1-17. DOI
  2021	Rabiei, M., Low, W. Y., Ren, Y., Cahyono, M. I., Doan, P. T. K., Dharmayanti, I., . . . Hemmatzadeh, F. (2021). Indicators of the molecular pathogenesis of virulent Newcastle disease virus in chickens revealed by transcriptomic profiling of spleen.. Sci Rep, 11(1), 1-14. DOI Scopus2 WoS1 Europe PMC1
  2021	Macphillamy, C., Pitchford, W. S., Alinejad-Rokny, H., & Low, W. Y. (2021). Opportunity to improve livestock traits using 3D genomics. Animal Genetics, 52(6), 785-798. DOI
  2020	Rosen, B. D., Bickhart, D. M., Schnabel, R. D., Koren, S., Elsik, C. G., Tseng, E., . . . Medrano, J. F. (2020). De novo assembly of the cattle reference genome with single-molecule sequencing.. GigaScience, 9(3), 9 pages. DOI Scopus200 WoS197 Europe PMC148
  2020	Chong, C. W., Alkatheeri, A. H. S., Ali, N., Tay, Z. H., Lee, Y. L., Paramasivam, S. J., . . . Lim, S. H. E. (2020). Association of antimicrobial resistance and gut microbiota composition in human and non-human primates at an urban ecotourism site.. Gut Pathogens, 12(1), 14. DOI Scopus3 WoS2 Europe PMC1
  2020	Barbato, M., Reichel, M. P., Passamonti, M., Low, W. Y., Colli, L., Tearle, R., . . . Ajmone Marsan, P. (2020). A genetically unique Chinese cattle population shows evidence of common ancestry with wild species when analysed with a reduced ascertainment bias SNP panel.. PLoS One, 15(4), 1-6. DOI Scopus4 WoS4 Europe PMC4
  2020	Low, W. Y., Tearle, R., Liu, R., Koren, S., Rhie, A., Bickhart, D. M., . . . Williams, J. L. (2020). Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle. Nature communications, 11(1), 1-14. DOI Scopus44 WoS47 Europe PMC32
  2020	Nowland, T. L., Torok, V. A., Low, W. Y., Barton, M. D., Plush, K. J., & Kirkwood, R. N. (2020). Faecal microbiota analysis of piglets during lactation. Animals, 10(5), 13 pages. DOI Scopus3 WoS3 Europe PMC2
  2020	Rabiei, M., Cahyono, M. I., Doan, P. T. K., Pandarangga, P., Tarigan, S., Indriani, R., . . . Hemmatzadeh, F. (2020). Genome Sequences of Newly Emerged Newcastle Disease Virus Strains Isolated from Disease Outbreaks in Indonesia.. Microbiol Resour Announc, 9(23), 4 pages. DOI Scopus3 Europe PMC2
  2020	Pandarangga, P., Cahyono, M. I., McAllister, M. M., Peaston, A. E., Tearle, R., Low, W. Y., . . . Hemmatzadeh, F. (2020). Full-Genome Sequences of Two Newcastle Disease Virus Strains Isolated in West Java, Indonesia.. Microbiology resource announcements, 9(24), e00221-e00220. DOI Scopus2 Europe PMC1
  2020	Doan, P. T. K., Cahyono, M. I., Rabiei, M., Pandarangga, P., McAllister, M. M., Low, W. Y., . . . Hemmatzadeh, F. (2020). Genome Sequences of Newcastle Disease Virus Strains from Two Outbreaks in Indonesia.. Microbiology resource announcements, 9(23), e00205-e00220. DOI Scopus5 Europe PMC3
  2020	Lai, P. -J., Ng, E. -V., Yang, S. -K., Moo, C. -L., Low, W. Y., Yap, P. S. -X., . . . Lai, K. -S. (2020). Transcriptomic analysis of multi-drug resistant Escherichia coli K-12 strain in response to Lavandula angustifolia essential oil.. 3 Biotech, 10(7), 1-9. DOI Scopus8 WoS6 Europe PMC4
  2020	Ong, J. S., Liu, Y. W., Liong, M. T., Choi, S. B., Tsai, Y. C., & Low, W. Y. (2020). Molecular evolutionary and 3D protein structural analyses of Lactobacillus fermentum elongation factor Tu, a novel brain health promoting factor. Genomics, 112(6), 3915-3924. DOI Scopus1 WoS1
  2020	Ren, Y., Yu, M., Low, W. Y., Ruhlman, T. A., Hajrah, N. H., El Omri, A., . . . Rather, I. A. (2020). Nucleotide substitution rates of diatom plastid encoded protein genes are positively correlated with genome architecture.. Scientific reports, 10(1), 14358. DOI Scopus3 WoS3 Europe PMC1
  2020	Rabiei, M., Cahyono, M. I., Doan, P. T. K., Pandarangga, P., Tarigan, S., Indriani, R., . . . Hemmatzadeh, F. (2020). Correction for Rabiei et al., "Genome Sequences of Newly Emerged Newcastle Disease Virus Strains Isolated from Disease Outbreaks in Indonesia".. Microbiol Resour Announc, 9(38), e00681-e00620. DOI
  2020	Dutta, P., Talenti, A., Young, R., Jayaraman, S., Callaby, R., Jadhav, S. K., . . . Prendergast, J. G. D. (2020). Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication.. Nature communications, 11(1), 1-13. DOI Scopus22 WoS21 Europe PMC13
  2020	Nowland, T. L., Torok, V. A., Low, W. Y., Plush, K. J., Barton, M. D., & Kirkwood, R. N. (2020). A Single Faecal Microbiota Transplantation Altered the Microbiota of Weaned Pigs.. Life (Basel, Switzerland), 10(9), 17 pages. DOI Scopus2 WoS2 Europe PMC1
  2019	Low, W. Y., Tearle, R., Bickhart, D., Rosen, B., Kingan, S., Swale, T., . . . Williams, J. (2019). Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity. Nature Communications, 10(1), 1-11. DOI Scopus79 WoS86 Europe PMC54
  2019	Liu, S., Kang, X., Catacchio, C. R., Liu, M., Fang, L., Schroeder, S. G., . . . Liu, G. E. (2019). Computational detection and experimental validation of segmental duplications and associated copy number variations in water buffalo (Bubalus bubalis). Functional and Integrative Genomics, 19(3), 409-419. DOI Scopus5 WoS5 Europe PMC1
  2019	Liu, Y. W., Ong, J. S., Gan, C. Y., Khoo, B. Y., Yahaya, S., Choi, S. B., . . . Liong, M. T. (2019). Lactobacillus fermentum PS150 showed psychotropic properties by altering serotonergic pathway during stress. Journal of Functional Foods, 59, 352-361. DOI Scopus10 WoS8
  2019	Low, W. Y., Tearle, R., Liu, R., Koren, S., Rhie, A., Bickhart, D., . . . Williams, J. (2019). Haplotype-Resolved Cattle Genomes Provide Insights Into Structural Variation and Adaptation. DOI
  2019	Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (2019). New insights into mammalian sex chromosome structure and evolution using high-quality sequences from bovine X and Y chromosomes.. BMC Genomics, 20(1), 1000. DOI Scopus15 WoS17 Europe PMC12
  2018	Tan, H., & Low, W. Y. (2018). Rapid birth-death evolution and positive selection in detoxification-type glutathione S-transferases in mammals. PLoS ONE, 13(12), 1-15. DOI Scopus9 WoS8 Europe PMC5
  2017	Davis, G. M., Low, W. Y., Anderson, J. W., & Boag, P. R. (2017). Exploring potential germline associated roles of the TRIM-NHL protein NHL-2 through RNAi screening. G3 : Genes, Genomes, Genetics, 7(10), 3251-3256. DOI Scopus5 WoS5 Europe PMC1
  2017	Williams, J., Iamartino, D., Pruitt, K., Sonstegard, T., Smith, T., Low, W., . . . Zimin, A. (2017). Genome assembly and transcriptome resource for river buffalo, Bubalus bubalis (2n = 50). GigaScience, 6(10), 1-6. DOI Scopus30 WoS29 Europe PMC22
  2017	Lye, H., Kato, T., Low, W., Taylor, T., Prakash, T., Lew, L., . . . Liong, M. (2017). Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration of gut microbiota. Journal of Biotechnology, 262, 75-83. DOI Scopus38 WoS33 Europe PMC12
  2017	Kanagarajah, R. R., Lee, D. C. W., Lee, D. Z. F., Yusoff, K., Paramasivam, S. J., Low, W. Y., . . . Lim, S. H. E. (2017). Antibiotic profiling of Methicillin Resistant Staphylococcus aureus (MRSA) isolates in stray canines and felines. Cogent Biology, 3(1), 1412280. DOI
  2013	Sengupta, M., Low, W., Patterson, J., Kim, H. -M., Traven, A., Beilharz, T., . . . Boag, P. (2013). ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans. Journal of Cell Science, 126(3), 850-859. DOI WoS25 Europe PMC20
  2010	Low, W., Feil, S., Ng, H., Gorman, M., Morton, C., Pyke, J., . . . Batterham, P. (2010). Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1. Journal of Molecular Biology, 399(3), 358-366. DOI Scopus57 WoS56 Europe PMC33
  2007	Low, W. Y., Ng, H. L., Morton, C. J., Parker, M. W., Batterham, P., & Robin, C. (2007). Molecular evolution of glutathione S-transferases in the genus Drosophila. Genetics, 177(3), 1363-1375. DOI WoS78 Europe PMC66
  2007	Clark, A. G., Eisen, M. B., Smith, D. R., Bergman, C. M., Oliver, B., Markow, T. A., . . . Han, M. V. (2007). Evolution of genes and genomes on the Drosophila phylogeny. Nature, 450(7167), 203-218. DOI Scopus1524 WoS1488 Europe PMC1290
  2005	Low, W. Y. (2005). Homocysteine, Folic Acid and Vitamin C in Young Malaysian Smokers and Non Smokers. Malaysian Journal of Biochemistry and Molecular Biology.
  -	Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (n.d.). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. DOI
  -	Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (n.d.). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. DOI
  -	Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (n.d.). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. DOI

• Book Chapters

  Year	Citation
  2019	Ong, C. K., Kwong, Q. B., Ong, A. L., Heng, H. Y., & Low, W. Y. (2019). Pipeline of High Throughput Sequencing. In S. Ranganathan, M. Gribskov, K. Nakai, & C. Schönbach (Eds.), Encyclopedia of Bioinformatics and Computational Biology (Vol. 3, pp. 144-151). Elsevier. DOI
  2017	Low, W. L., & Tammi, M. T. (2017). Introduction to next generation sequencing technologies. In W. L. Low, & M. Tammi (Eds.), Bioinformatics: A practical handbook of next generation sequencing and Its applications (pp. 1-21). World Scientific Publishing. DOI

• Conference Papers

  Year	Citation
  2018	Vidovic, S., & An, R. (2018). The influence of single nucleotide polymorphism (SNP) mutations in gyrA, gyrB, parC and parE on the acquisition of fluoroquinolone and cross-resistances in Salmonella enterica subspecies enterica serovar Enteritidis. In Archives of Clinical Microbiology Vol. 04. OMICS Publishing Group. DOI
  2017	Low, W. (2017). Population entropies estimates of proteins. In Proceedings of the 3rd ISM International Statistical Conference 2016: Bringing Professionalism and Prestige in Statistics, as published in AIP Conference Proceedings Vol. 1842 (pp. 1-7). Kuala Lumpur, Malaysia: American Institute of Physics. DOI Scopus1 WoS1

• Patents

  Year	Citation
  2017	Low, W. Y. (2017). WO 2018/129722 A1, A novel lactic acid bacteria and its applications. Taiwan.

• Theses

  Year	Citation
  2009	Low, W. Y. (2009). Molecular evolution, structure and function of Glutathione S-Transferases in the genus Drosophila. (PhD Thesis, The University of Melbourne).

Taught Biostatistics, Genetics and Molecular Evolution to post-graduate students at Perdana University (Sep 2014 – Jan 2017).

Senior Lecturer and Head of Biotechnology undergraduate program at the Manipal International University (Aug 2013 – Sep 2014). Taught Computational Biology and Genetics to undergraduate students and prepared documents in compliance with Malaysian Qualifications Agency (MQA).

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2021	Principal Supervisor	Bovine Pangenome Assembly	Master of Philosophy	Master	Full Time	Miss Paulene Santos Pineda
  2020	Principal Supervisor	Deciphering 3D Genome Structure of Ruminants using Machine Learning	Doctor of Philosophy	Doctorate	Full Time	Mr Callum Macphillamy
  2019	Co-Supervisor	Antimicrobial resistance in Escherichia coli and enterococci isolated from beef cattle	Doctor of Philosophy	Doctorate	Full Time	Dr Yohannes Equar Messele

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2019 - 2021	Co-Supervisor	Investigation of the molecular pathogenesis of newly emerged Newcastle disease virus in Indonesia	Doctor of Philosophy	Doctorate	Full Time	Mr Mohammad Rabiei

• Memberships

  Date	Role	Membership	Country
  2016 - ongoing	Member	The Asia Pacific Bioinformatics Network	-

• Position: Grant-Funded Researcher (C)
• Phone: 83130030
• Email: wai.low@adelaide.edu.au
• Campus: Roseworthy
• Building: J.S. Davies, floor G
• Org Unit: School of Animal and Veterinary Science