Research Interests
Bioinformatics Biostatistics Genetics Genome Structure and Regulation Molecular EvolutionDr Wai Low
Grant-Funded Senior Research Fellow
School of Animal and Veterinary Sciences
College of Science
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
I have more than 10 years post-doctoral experience in academia, mainly in genomics and bioinformatics. I have expertise in analysing genomic data of a diverse range of bovine species such as cattle, water buffalo and gaur, which has resulted more than 50 research publications, including multiple papers in Nature Communications and Nature. I have edited 2 books, authored 2 book chapters and has an international patent. One of my Nature Communications papers described a high-quality water buffalo reference genome that was the most contiguous mammalian reference genome at the time of publication. This paper has received substantial online attention and was featured as a news feed item by the Roslin Institute, a world leader in animal research, and by Pacific Biosciences, a key company innovating in the field of long-read sequencing. I have created the first indicine cattle (Brahman) reference genome and played a key role in the creation of more cattle genomes through my affiliation with the Bovine Pangenome Consortium. Please get in touch with me if you wish to pursue advanced studies in bioinformatics.
I am currently a Bioinformatics Data Scientist at Davies Research Centre, University of Adelaide. My research interests are in the areas of next generation sequencing (NGS) technology, genome assembly, gene annotation, molecular evolution, transcriptomics, comparative genomics and metagenomics. The species I have worked on include fly, worm, human, primate, bacteria, water buffalo and cattle. I have authored/co-authored research articles at internationally recognized, peer-reviewed journals and I have presented my work at numerous international conferences. I am a co-author of two patents related to the important discovery and genomic analyses of a probiotic bacteria. I have also written a practical handbook on NGS and regularly contributing to a bioinformatics website (https://bioinformaticshome.com).
| Date | Position | Institution name |
|---|---|---|
| 2017 - ongoing | Bioinformatics data scientist | University of Adelaide |
| 2014 - 2017 | Assistant Professor | Perdana University |
| Language | Competency |
|---|---|
| Chinese (Cantonese) | Can speak and understand spoken |
| English | Can read, write, speak, understand spoken and peer review |
| Malay | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2017 - 2022 | University of Adelaide | Australia | Post-graduate Diploma in Biostatistics |
| 2009 - 2009 | University of Melbourne | Australia | PhD (Genetics) |
| Year | Citation |
|---|---|
| 2025 | Ge, F., Guo, Y., Xu, L., Low, W. Y., Ma, H., Li, Q., . . . Chen, Y. (2025). The chromosome-level genome of Chinese indicine cattle breed provides insights into bovine adaptation and immunity.. DNA Res, dsaf034. |
| 2025 | Pineda, P. S., MacPhillamy, C., Ren, Y., Chen, T., Zhong, L., Adelson, D. L., . . . Low, W. Y. (2025). Insights into natural neocentromere evolution from a cattle T2T X chromosome. Nature Communications, 16(1), 16 pages. |
| 2025 | Xia, X., Wang, F., Luo, X., Li, S., Lyu, Y., Zheng, Y., . . . Chen, N. (2025). Structural Variations Associated with Adaptation and Coat Color in Qinghai-Tibetan Plateau Cattle. Advanced Science, 12(31), 17 pages. Scopus2 WoS2 Europe PMC2 |
| 2024 | Rabiei, M., McAllister, M. M., Gassman, N. R., Lee, K. J., Acton, S., Liebhart, D., . . . Hemmatzadeh, F. (2024). Newcastle Disease Virus Induces Profound Lymphoid Depletion with Different Patterns of Necroptosis, Necrosis, and Oxidative DNA Damage in Bursa, Spleen, and Other Lymphoid Tissues. Pathogens, 13(8), 619. Scopus1 WoS1 Europe PMC1 |
| 2024 | Pandarangga, P., Doan, P. T. K., Tearle, R., Low, W. Y., Ren, K., Nguyen, H. T. H., . . . Hemmatzadeh, F. (2024). mRNA Profiling and Transcriptomics Analysis of Chickens Received Newcastle Disease Virus Genotype II and Genotype VII Vaccines. Pathogens, 13(8), 23 pages. Scopus1 WoS1 Europe PMC1 |
| 2024 | Kalbfleisch, T. S., McKay, S. D., Murdoch, B. M., Adelson, D. L., Almansa-Villa, D., Becker, G., . . . Rosen, B. D. (2024). The Ruminant Telomere-to-Telomere (RT2T) Consortium. Nature Genetics, 56(8), 1566-1573. Scopus13 WoS13 Europe PMC14 |
| 2024 | Pineda, P. S., Flores, E. B., Villamor, L. P., Parac, C. J. M., Khatkar, M. S., Thu, H. T., . . . 1000 Buffalo Genomes Consortium. (2024). Disentangling river and swamp buffalo genetic diversity: initial insights from the 1000 Buffalo Genomes Project.. GigaScience, 13, 14 pages. Scopus6 WoS6 Europe PMC5 |
| 2024 | Ren, Y., Khatkar, M. S., MacPhillamy, C., Wang, H., McEwin, R. A., Chen, T., . . . Low, W. Y. (2024). Evaluating the Efficacy of Target Capture Sequencing for Genotyping in Cattle. Genes, 15(9), 1218. |
| 2024 | Low, W. Y. (2024). The case for bovine pangenome. Animal Research and One Health, 2(4), 363-365. Scopus2 WoS2 |
| 2024 | MacPhillamy, C., Chen, T., Hiendleder, S., Williams, J. L., Alinejad-Rokny, H., & Low, W. Y. (2024). DNA methylation analysis to differentiate reference, breed, and parent-of-origin effects in the bovine pangenome era. Gigascience, 13, giae061-1-giae061-18. Scopus6 WoS5 Europe PMC5 |
| 2024 | Jafari Jozani, R., Khallawi, M. F. H. A., Trott, D., Petrovski, K., Low, W. Y., & Hemmatzadeh, F. (2024). Unravelling Antimicrobial Resistance in Mycoplasma hyopneumoniae: Genetic Mechanisms and Future Directions. Veterinary Sciences, 11(11), 17 pages. Scopus2 WoS2 Europe PMC1 |
| 2024 | Jafari Jozani, R., Khallawi, M. F. H. A., Nguyen, H. T. H., Mohammed, M. H., Petrovski, K., Ren, Y., . . . Low, W. Y. (2024). Phenotypic and Genotypic Analysis of Antimicrobial Resistance in Mycoplasma hyopneumoniae Isolated from Pigs with Enzootic Pneumonia in Australia. Pathogens, 13(12), 13 pages. |
| 2024 | Kalbfleisch, T. S., McKay, S. D., Murdoch, B. M., Adelson, D. L., Almansa-Villa, D., Becker, G., . . . Rosen, B. D. (2024). The Ruminant Telomere-to-Telomere (RT2T) Consortium. NATURE GENETICS, 56(8), 8 pages. WoS13 |
| 2023 | Smith, T. P. L., Bickhart, D. M., Boichard, D., Chamberlain, A. J., Djikeng, A., Jiang, Y., . . . Bovine Pangenome Consortium. (2023). The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species.. Genome biology, 24(1), 139. Scopus37 WoS33 Europe PMC33 |
| 2023 | Messele, Y. E., Trott, D. J., Hasoon, M. F., Veltman, T., McMeniman, J. P., Kidd, S. P., . . . Low, W. Y. (2023). Phylogeny, Virulence, and Antimicrobial Resistance Gene Profiles of Enterococcus faecium Isolated from Australian Feedlot Cattle and Their Significance to Public and Environmental Health. Antibiotics, 12(7), 1122. Scopus8 WoS8 Europe PMC4 |
| 2023 | Messele, Y. E., Hasoon, M. F., Trott, D. J., Veltman, T., McMeniman, J. P., Kidd, S. P., . . . Petrovski, K. R. (2023). Correction: Messele et al. Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit. Animals 2022, 12, 2690. Animals, 13(16), 2684. |
| 2023 | MacPhillamy, C., Ren, Y., Chen, T., Hiendleder, S., & Low, W. Y. (2023). MicroRNA breed and parent-of-origin effects provide insights into biological pathways differentiating cattle subspecies in fetal liver. Frontiers in Genetics, 14, 13 pages. Scopus1 WoS1 Europe PMC1 |
| 2023 | Ren, Y., Tseng, E., Smith, T. P. L., Hiendleder, S., Williams, J. L., & Low, W. Y. (2023). Long read isoform sequencing reveals hidden transcriptional complexity between cattle subspecies.. BMC genomics, 24(1), 15 pages. Scopus4 WoS4 Europe PMC6 |
| 2023 | Aldersey, J. E., Liu, N., Tearle, R., Low, W. Y., Breen, J., Williams, J. L., & Bottema, C. D. K. (2023). Topologically associating domains in the POLLED region are the same for Angus- and Brahman-specific Hi-C reads from F1 hybrid fetal tissue.. Anim Genet, 54(4), 536-543. Scopus1 WoS1 Europe PMC1 |
| 2023 | Messele, Y. E., Trott, D. J., Hasoon, M. F., Veltman, T., McMeniman, J. P., Kidd, S. P., . . . Low, W. Y. (2023). Phylogenetic Analysis of Escherichia coli Isolated from Australian Feedlot Cattle in Comparison to Pig Faecal and Poultry/Human Extraintestinal Isolates. Antibiotics, 12(5), 895. Scopus8 WoS8 Europe PMC8 |
| 2022 | Doan, P. T. K., Low, W. Y., Ren, Y., Tearle, R., & Hemmatzadeh, F. (2022). Newcastle disease virus genotype VII gene expression in experimentally infected birds.. Scientific reports, 12(1), 8 pages. Scopus8 WoS6 Europe PMC3 |
| 2022 | Low, W. Y., Rosen, B. D., Ren, Y., Bickhart, D. M., To, T. -H., Martin, F. J., . . . Smith, T. P. L. (2022). Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle.. BMC genomics, 23(1), 15 pages. Scopus9 WoS9 Europe PMC8 |
| 2022 | Alhamami, T., Low, W. Y., Ren, Y., Taylor, K., Khazandi, M., Veltman, T., . . . Trott, D. J. (2022). Antimicrobial susceptibility and genomic analysis of Histophilus somni isolated from cases of bovine respiratory disease in Autralian feedlot cattle.. Veterinary microbiology, 270(109460), 1-9. Scopus6 WoS6 Europe PMC4 |
| 2022 | MacPhillamy, C., Alinejad-Rokny, H., Pitchford, W. S., & Low, W. Y. (2022). Cross-species enhancer prediction using machine learning.. Genomics, 114(5), 1-12. Scopus12 WoS12 Europe PMC9 |
| 2022 | Messele, Y. E., Alkhallawi, M., Veltman, T., Trott, D. J., McMeniman, J. P., Kidd, S. P., . . . Petrovski, K. R. (2022). Phenotypic and Genotypic Analysis of Antimicrobial Resistance in Escherichia coli Recovered from Feedlot Beef Cattle in Australia. Animals, 12(17), 1-15. Scopus16 WoS14 Europe PMC8 |
| 2022 | Messele, Y. E., Hasoon, M. F., Trott, D. J., Veltman, T., McMeniman, J. P., Kidd, S. P., . . . Petrovski, K. R. (2022). Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit. Animals, 12(19), 18 pages. Scopus13 WoS11 Europe PMC10 |
| 2021 | Abdel-Shafy, H., Deng, T., Zhou, Y., Low, W. Y., & Hua, G. (2021). Editorial: Buffalo Genetics and Genomics.. Front Genet, 12, 820627. Scopus3 WoS2 Europe PMC1 |
| 2021 | Macciotta, N. P. P., Colli, L., Cesarani, A., Ajmone-Marsan, P., Low, W. Y., Tearle, R., & Williams, J. L. (2021). The distribution of runs of homozygosity in the genome of river and swamp buffaloes reveals a history of adaptation, migration and crossbred events.. Genet Sel Evol, 53(1), 1-21. Scopus28 WoS27 Europe PMC21 |
| 2021 | Pineda, P. S., Flores, E. B., Herrera, J. R. V., & Low, W. Y. (2021). Opportunities and Challenges for Improving the Productivity of Swamp Buffaloes in Southeastern Asia.. Frontiers in genetics, 12, 629861. Scopus35 WoS21 Europe PMC11 |
| 2021 | Kronenberg, Z. N., Rhie, A., Koren, S., Concepcion, G. T., Peluso, P., Munson, K. M., . . . Kingan, S. B. (2021). Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C.. Nature communications, 12(1), 1935. Scopus88 WoS87 Europe PMC99 |
| 2021 | Stephenson, T., Speight, N., Low, W. Y., Woolford, L., Tearle, R., & Hemmatzadeh, F. (2021). Molecular Diagnosis of Koala Retrovirus (KoRV) in South Australian Koalas (Phascolarctos cinereus). Animals, 11(5), 1-13. Scopus9 WoS9 Europe PMC8 |
| 2021 | Liu, R., Tearle, R., Low, W. Y., Chen, T., Thomsen, D., Smith, T. P. L., . . . Williams, J. L. (2021). Distinctive gene expression patterns and imprinting signatures revealed in reciprocal crosses between cattle sub-species. BMC Genomics, 22(1), 1-10. Scopus9 WoS8 Europe PMC7 |
| 2021 | Ren, Y., Macphillamy, C., To, T. -H., Smith, T. P. L., Williams, J. L., & Low, W. Y. (2021). Adaptive selection signatures in river buffalo with emphasis on immune and major histocompatibility complex genes.. Genomics, 113(6), 3599-3609. Scopus8 WoS6 Europe PMC5 |
| 2021 | Liu, N., Low, W. Y., Alinejad-Rokny, H., Pederson, S., Sadlon, T., Barry, S., & Breen, J. (2021). Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C. Epigenetics & chromatin, 14(1), 1-17. Scopus8 WoS8 Europe PMC11 |
| 2021 | Rabiei, M., Low, W. Y., Ren, Y., Cahyono, M. I., Doan, P. T. K., Dharmayanti, I., . . . Hemmatzadeh, F. (2021). Indicators of the molecular pathogenesis of virulent Newcastle disease virus in chickens revealed by transcriptomic profiling of spleen.. Sci Rep, 11(1), 1-14. Scopus18 WoS17 Europe PMC13 |
| 2021 | Macphillamy, C., Pitchford, W. S., Alinejad-Rokny, H., & Low, W. Y. (2021). Opportunity to improve livestock traits using 3D genomics. Animal Genetics, 52(6), 785-798. Scopus3 WoS2 Europe PMC2 |
| 2020 | Rosen, B. D., Bickhart, D. M., Schnabel, R. D., Koren, S., Elsik, C. G., Tseng, E., . . . Medrano, J. F. (2020). De novo assembly of the cattle reference genome with single-molecule sequencing.. GigaScience, 9(3), 9 pages. Scopus463 WoS460 Europe PMC461 |
| 2020 | Chong, C. W., Alkatheeri, A. H. S., Ali, N., Tay, Z. H., Lee, Y. L., Paramasivam, S. J., . . . Lim, S. H. E. (2020). Association of antimicrobial resistance and gut microbiota composition in human and non-human primates at an urban ecotourism site.. Gut Pathogens, 12(1), 14. Scopus21 WoS17 Europe PMC13 |
| 2020 | Barbato, M., Reichel, M. P., Passamonti, M., Low, W. Y., Colli, L., Tearle, R., . . . Ajmone Marsan, P. (2020). A genetically unique Chinese cattle population shows evidence of common ancestry with wild species when analysed with a reduced ascertainment bias SNP panel.. PLoS One, 15(4), 1-6. Scopus13 WoS13 Europe PMC11 |
| 2020 | Low, W. Y., Tearle, R., Liu, R., Koren, S., Rhie, A., Bickhart, D. M., . . . Williams, J. L. (2020). Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle. Nature communications, 11(1), 1-14. Scopus97 WoS94 Europe PMC91 |
| 2020 | Nowland, T. L., Torok, V. A., Low, W. Y., Barton, M. D., Plush, K. J., & Kirkwood, R. N. (2020). Faecal microbiota analysis of piglets during lactation. Animals, 10(5), 1-13. Scopus6 WoS7 Europe PMC7 |
| 2020 | Rabiei, M., Cahyono, M. I., Doan, P. T. K., Pandarangga, P., Tarigan, S., Indriani, R., . . . Hemmatzadeh, F. (2020). Genome Sequences of Newly Emerged Newcastle Disease Virus Strains Isolated from Disease Outbreaks in Indonesia.. Microbiol Resour Announc, 9(23), 4 pages. Scopus4 WoS3 Europe PMC3 |
| 2020 | Pandarangga, P., Cahyono, M. I., McAllister, M. M., Peaston, A. E., Tearle, R., Low, W. Y., . . . Hemmatzadeh, F. (2020). Full-Genome Sequences of Two Newcastle Disease Virus Strains Isolated in West Java, Indonesia.. Microbiology resource announcements, 9(24), 2 pages. Scopus7 WoS6 Europe PMC6 |
| 2020 | Doan, P. T. K., Cahyono, M. I., Rabiei, M., Pandarangga, P., McAllister, M. M., Low, W. Y., . . . Hemmatzadeh, F. (2020). Genome Sequences of Newcastle Disease Virus Strains from Two Outbreaks in Indonesia.. Microbiology resource announcements, 9(23), 3 pages. Scopus8 WoS8 Europe PMC7 |
| 2020 | Lai, P. -J., Ng, E. -V., Yang, S. -K., Moo, C. -L., Low, W. Y., Yap, P. S. -X., . . . Lai, K. -S. (2020). Transcriptomic analysis of multi-drug resistant Escherichia coli K-12 strain in response to Lavandula angustifolia essential oil.. 3 Biotech, 10(7), 1-9. Scopus11 WoS9 Europe PMC8 |
| 2020 | Ong, J. S., Liu, Y. W., Liong, M. T., Choi, S. B., Tsai, Y. C., & Low, W. Y. (2020). Molecular evolutionary and 3D protein structural analyses of Lactobacillus fermentum elongation factor Tu, a novel brain health promoting factor. Genomics, 112(6), 3915-3924. Scopus4 WoS4 Europe PMC1 |
| 2020 | Ren, Y., Yu, M., Low, W. Y., Ruhlman, T. A., Hajrah, N. H., El Omri, A., . . . Rather, I. A. (2020). Nucleotide substitution rates of diatom plastid encoded protein genes are positively correlated with genome architecture.. Scientific reports, 10(1), 14358. Scopus8 WoS6 Europe PMC4 |
| 2020 | Rabiei, M., Cahyono, M. I., Doan, P. T. K., Pandarangga, P., Tarigan, S., Indriani, R., . . . Hemmatzadeh, F. (2020). Correction for Rabiei et al., "Genome Sequences of Newly Emerged Newcastle Disease Virus Strains Isolated from Disease Outbreaks in Indonesia".. Microbiol Resour Announc, 9(38), 2 pages. |
| 2020 | Dutta, P., Talenti, A., Young, R., Jayaraman, S., Callaby, R., Jadhav, S. K., . . . Prendergast, J. G. D. (2020). Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication.. Nature communications, 11(1), 1-13. Scopus58 WoS52 Europe PMC49 |
| 2020 | Nowland, T. L., Torok, V. A., Low, W. Y., Plush, K. J., Barton, M. D., & Kirkwood, R. N. (2020). A Single Faecal Microbiota Transplantation Altered the Microbiota of Weaned Pigs.. Life (Basel, Switzerland), 10(9), 17 pages. Scopus8 WoS7 Europe PMC7 |
| 2019 | Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (2019). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. |
| 2019 | Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (2019). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. |
| 2019 | Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (2019). New Insights into Mammalian Sex Chromosome Structure and Evolution from High-quality Bovine X and Y Chromosome Sequences. |
| 2019 | Low, W. Y., Tearle, R., Bickhart, D., Rosen, B., Kingan, S., Swale, T., . . . Williams, J. (2019). Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity. Nature Communications, 10(1), 1-11. Scopus116 WoS118 Europe PMC113 |
| 2019 | Liu, S., Kang, X., Catacchio, C. R., Liu, M., Fang, L., Schroeder, S. G., . . . Liu, G. E. (2019). Computational detection and experimental validation of segmental duplications and associated copy number variations in water buffalo (Bubalus bubalis). Functional and Integrative Genomics, 19(3), 409-419. Scopus13 WoS12 Europe PMC9 |
| 2019 | Liu, Y. W., Ong, J. S., Gan, C. Y., Khoo, B. Y., Yahaya, S., Choi, S. B., . . . Liong, M. T. (2019). Lactobacillus fermentum PS150 showed psychotropic properties by altering serotonergic pathway during stress. Journal of Functional Foods, 59, 352-361. Scopus21 WoS17 |
| 2019 | Low, W. Y., Tearle, R., Liu, R., Koren, S., Rhie, A., Bickhart, D., . . . Williams, J. (2019). Haplotype-Resolved Cattle Genomes Provide Insights Into Structural Variation and Adaptation. Europe PMC1 |
| 2019 | Liu, R., Low, W. Y., Tearle, R., Koren, S., Ghurye, J., Rhie, A., . . . Williams, J. L. (2019). New insights into mammalian sex chromosome structure and evolution using high-quality sequences from bovine X and Y chromosomes.. BMC Genomics, 20(1), 1000. Scopus32 WoS32 Europe PMC25 |
| 2018 | Tan, H., & Low, W. Y. (2018). Rapid birth-death evolution and positive selection in detoxification-type glutathione S-transferases in mammals. PLoS ONE, 13(12), 1-15. Scopus17 WoS16 Europe PMC12 |
| 2017 | Davis, G. M., Low, W. Y., Anderson, J. W., & Boag, P. R. (2017). Exploring potential germline associated roles of the TRIM-NHL protein NHL-2 through RNAi screening. G3 : Genes, Genomes, Genetics, 7(10), 3251-3256. Scopus7 WoS6 Europe PMC6 |
| 2017 | Williams, J., Iamartino, D., Pruitt, K., Sonstegard, T., Smith, T., Low, W., . . . Zimin, A. (2017). Genome assembly and transcriptome resource for river buffalo, Bubalus bubalis (2n = 50). GigaScience, 6(10), 1-6. Scopus42 WoS41 Europe PMC36 |
| 2017 | Lye, H., Kato, T., Low, W., Taylor, T., Prakash, T., Lew, L., . . . Liong, M. (2017). Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration of gut microbiota. Journal of Biotechnology, 262, 75-83. Scopus60 WoS50 Europe PMC35 |
| 2017 | Kanagarajah, R. R., Lee, D. C. W., Lee, D. Z. F., Yusoff, K., Paramasivam, S. J., Low, W. Y., . . . Lim, S. H. E. (2017). Antibiotic profiling of Methicillin Resistant Staphylococcus aureus (MRSA) isolates in stray canines and felines. Cogent Biology, 3(1), 10 pages. WoS5 |
| 2013 | Sengupta, M., Low, W., Patterson, J., Kim, H. -M., Traven, A., Beilharz, T., . . . Boag, P. (2013). ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans. Journal of Cell Science, 126(3), 850-859. Scopus33 WoS34 Europe PMC38 |
| 2010 | Low, W. Y., Feil, S. C., Ng, H. L., Gorman, M. A., Morton, C. J., Pyke, J., . . . Batterham, P. (2010). Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1. Journal of Molecular Biology, 399(3), 358-366. Scopus71 WoS69 Europe PMC58 |
| 2007 | Low, W. Y., Ng, H. L., Morton, C. J., Parker, M. W., Batterham, P., & Robin, C. (2007). Molecular evolution of glutathione S-transferases in the genus Drosophila. Genetics, 177(3), 1363-1375. WoS88 Europe PMC84 |
| 2007 | Clark, A. G., Eisen, M. B., Smith, D. R., Bergman, C. M., Oliver, B., Markow, T. A., . . . Han, M. V. (2007). Evolution of genes and genomes on the Drosophila phylogeny. Nature, 450(7167), 203-218. Scopus1620 WoS1575 Europe PMC1606 |
| 2005 | Low, W. Y. (2005). Homocysteine, Folic Acid and Vitamin C in Young Malaysian Smokers and Non Smokers. Malaysian Journal of Biochemistry and Molecular Biology. |
| Year | Citation |
|---|---|
| 2023 | MacPhillamy, C., & Low, W. Y. (2023). Predicting Human Enhancers with Machine Learning. In L. Low, & M. Tammi (Eds.), Practical Bioinformatics for Beginners: From Raw Sequence Analysis to Machine Learning Applications (pp. 223-250). London: World Scientific Publishing Co.. DOI |
| 2023 | Ren, Y., Saidin, A., & Low, W. Y. (2023). Transcriptomics. In Practical Bioinformatics for Beginners: From Raw Sequence Analysis to Machine Learning Applications (pp. 141-163). DOI |
| 2019 | Ong, C. K., Kwong, Q. B., Ong, A. L., Heng, H. Y., & Low, W. Y. (2019). Pipeline of High Throughput Sequencing. In S. Ranganathan, M. Gribskov, K. Nakai, & C. Schönbach (Eds.), Encyclopedia of Bioinformatics and Computational Biology (Vol. 3, pp. 144-151). Elsevier. DOI |
| 2019 | Ong, C. K., Kwong, Q. B., Ong, A. L., Heng, H. Y., & Low, W. Y. (2019). Pipeline of High Throughput Sequencing. In Encyclopedia of Bioinformatics and Computational Biology Abc of Bioinformatics (pp. 144-151). DOI |
| 2017 | Low, W. L., & Tammi, M. T. (2017). Introduction to next generation sequencing technologies. In W. L. Low, & M. Tammi (Eds.), Bioinformatics: A practical handbook of next generation sequencing and Its applications (pp. 1-21). World Scientific Publishing. DOI |
| Year | Citation |
|---|---|
| 2018 | Vidovic, S., & An, R. (2018). The influence of single nucleotide polymorphism (SNP) mutations in gyrA, gyrB, parC and parE on the acquisition of fluoroquinolone and cross-resistances in Salmonella enterica subspecies enterica serovar Enteritidis. In Archives of Clinical Microbiology Vol. 04. OMICS Publishing Group. DOI |
| 2017 | Low, W. (2017). Population entropies estimates of proteins. In Proceedings of the 3rd ISM International Statistical Conference 2016: Bringing Professionalism and Prestige in Statistics, as published in AIP Conference Proceedings Vol. 1842 (pp. 1-7). Kuala Lumpur, Malaysia: American Institute of Physics. DOI Scopus1 WoS1 |
| Year | Citation |
|---|---|
| 2022 | Messele, Y., Alkhallawi, M., Veltman, T., Trott, D., Mcmeniman, J., Kidd, S., . . . Petrovski, K. (2022). LONGITUDINAL ANALYSIS OF ANTIMICROBIAL RESISTANCE IN ESCHERICHIA COLI RECOVERED FROM FEEDLOT BEEF CATTLE IN AUSTRALIA. Poster session presented at the meeting of JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE. ELSEVIER SCI LTD. |
| Year | Citation |
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| 2017 | Low, W. Y. (2017). WO 2018/129722 A1, A novel lactic acid bacteria and its applications. Taiwan. |
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| 2009 | Low, W. Y. (2009). Molecular evolution, structure and function of Glutathione S-Transferases in the genus Drosophila. (PhD Thesis, The University of Melbourne). |
| Year | Citation |
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| 2025 | Low, W., Pineda, P., Macphillamy, C., Ren, Y., Chen, T., Zhong, L., . . . Smith, T. (2025). Cattle T2T X Chromosome: Insights into Natural Neocentromere Evolution. DOI |
| 2024 | Kalbfleisch, T., McKay, S., Murdoch, B., Adelson, D., Almansa, D., Becker, G., . . . Rosen, B. (2024). RT2T: A Global Collaborative Project to Study Chromosomal Evolution in the Suborder Ruminantia. DOI |
| 2024 | Kalbfleisch, T., McKay, S., Murdoch, B., Adelson, D. L., Almansa, D., Becker, G., . . . Rosen, B. (2024). RT2T: A Global Collaborative Project to Study Chromosomal Evolution in the Suborder Ruminantia. DOI |
A case control study to discover systemic gut microbiome changes in spinal muscular atrophy. (2016 - ongoing) Funded by the Malaysian Medical Association Foundation. Role: Principal Investigator
Post-transcriptional gene regulation in RNA-granules (2010 – 2013) Funded by National Health and Medical Research Council. Role: Postdoctoral Research Fellow.
Using comparative genomics to identify genes responsible for adaptation to environmental toxins (Discovery Projects) (2005 – 2008) Funded by Australia Research Council. Role: PhD student.
Taught Biostatistics, Genetics and Molecular Evolution to post-graduate students at Perdana University (Sep 2014 – Jan 2017).
Senior Lecturer and Head of Biotechnology undergraduate program at the Manipal International University (Aug 2013 – Sep 2014). Taught Computational Biology and Genetics to undergraduate students and prepared documents in compliance with Malaysian Qualifications Agency (MQA).
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Principal Supervisor | 1000 Buffalo Genomes Project: SNP Discovery for Establishing a Foundational Water Buffalo Genetic Resource | Master of Philosophy | Master | Full Time | Ms Connie Parac |
| 2025 | Principal Supervisor | 1000 Buffalo Genomes Project: SNP Discovery for Establishing a Foundational Water Buffalo Genetic Resource | Master of Philosophy | Master | Full Time | Ms Connie Parac |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2023 - 2025 | Principal Supervisor | Bovine Genome Assemblies | Doctor of Philosophy | Doctorate | Full Time | Miss Paulene Santos Pineda |
| 2020 - 2024 | Principal Supervisor | Genetic and Epigenetic Regulation in Angus and Brahman Cattle | Doctor of Philosophy | Doctorate | Full Time | Mr Callum Macphillamy |
| 2019 - 2023 | Co-Supervisor | Antimicrobial resistance in Escherichia coli and enterococci isolated from beef cattle | Doctor of Philosophy | Doctorate | Full Time | Dr Yohannes Equar Messele |
| 2019 - 2021 | Co-Supervisor | Investigation of the molecular pathogenesis of newly emerged Newcastle disease virus in Indonesia | Doctor of Philosophy | Doctorate | Full Time | Mr Mohammad Rabiei |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2016 - ongoing | Member | The Asia Pacific Bioinformatics Network | - |
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