Vishnu Sunil Jaikumar

Vishnu Sunil Jaikumar

Higher Degree by Research Candidate

School of Pharmacy and Biomedical Sciences

College of Health


Date Position Institution name
2019 - 2022 Veterinary Medical Officer Rajiv Gandhi Centre for Biotechnology
2016 - 2019 Veterinarian and Research Associate III Rajiv Gandhi Centre for Biotechnology
2015 - 2016 Veterinary Surgeon Animal Birth Control for Dogs (ABCD) Kochi
2014 - 2015 Research Assistant Kerala Veterinary and Animal Sciences University
2014 - 2015 Inpatient Unit Incharge Kerala Veterinary and Animal Sciences University

Date Type Title Institution Name Country Amount
2024 Award FEBS Open Bio Poster Prize ComBio 2024-Biomolecular Horizons 2024, Melbourne Australia -
2012 Scholarship Kerala Veterinary and Animal Sciences University Assistantship Kerala Veterinary and Animal Sciences University India -
2012 Award Best Clinical Case Presentation Award Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University India -

Language Competency
Divehi; Dhivehi; Maldivian Can understand spoken
English Can read, write, speak, understand spoken and peer review
Hindi Can read, speak and understand spoken
Malayalam Can read, write, speak and understand spoken
Tamil Can speak and understand spoken

Date Institution name Country Title
2012 - 2015 Kerala Veterinary and Animal Sciences University India Master of Veterinary Science
2007 - 2012 Rajiv Gandhi Institute of Veterinary Education and Research India Bachelor of Veterinary Science and Animal Husbandry

Date Title Institution name Country
Certificate in Laboratory Animal Science (FELASA A,B,C,D) Federation of European Laboratory Animal Science Associations -
Certificate in Avian Medicine QUADAM Institute -

Year Citation
2026 Rayginia, T. P., Keerthana, C. K., Aiswarya, S. U., Shifana, S. C., Jannet, S., Varma, S. S., . . . Anto, R. J. (2026). Orphan drug uttroside B impedes MASH progression and HCC development in experimental models. Jhep Reports, 8(2), 16 pages.
DOI
2026 Raj R, R., Datta, N., Krishnan U, S., Shanmugam, G., Louis, J. M., Jeyaram, R. D., . . . Maliekal, T. T. (2026). EPHA2-Ephrin-B1 cis-interaction drives an oncogenic reverse signaling, leading to the recurrence of oral cancer. Cell Communication and Signaling, 24(1), 300.
DOI
2026 Keerthana, C. K., Rayginia, T. P., Kalimuthu, K., Saha, S., Haritha, N. H., Nisthul Areekkara, A., . . . Anto, R. J. (2026). Uttroside B, a US FDA-designated ‘Orphan Drug’, mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3. Cell Death Discovery, 12(1), 250.
DOI
2025 Das, D. J., Jaikumar, V. S., Suryaletha, K., Paul, M., Shankar, A., Nath, S. R., & Thomas, S. (2025). Probiotic Lacticaseibacillus paracasei from human gut microbiome against colistin-resistant Klebsiella pneumoniae: in vitro, in vivo and probiogenomic approaches. Beneficial Microbes, 16(4), 443-463.
DOI Scopus2 WoS2 Europe PMC2
2025 Patra, D., Varghese, G. R., Jaikumar, V. S., Rajan, A., Krishnan, N., Kuppuswamy, K., . . . Srinivas, P. (2025). Decoding BRCA1 promoter hypermethylation: a new frontier in understanding sporadic breast cancer. Cancer Gene Therapy, online(12), 1-14.
DOI
2024 Nair, M. G., Mavatkar, A. D., Naidu, C. M., V. P, S., C. E, A., Rajarajan, S., . . . Prabhu, J. S. (2024). Elucidating the Role of MicroRNA-18a in Propelling a Hybrid Epithelial–Mesenchymal Phenotype and Driving Malignant Progression in ER-Negative Breast Cancer. Cells, 13(10), 24 pages.
DOI Scopus4 WoS4 Europe PMC3
2024 Remadevi, V., Jaikumar, V. S., Vini, R., Krishnendhu, B., Azeez, J. M., Sundaram, S., & Sreeja, S. (2024). Urolithin A, induces apoptosis and autophagy crosstalk in Oral Squamous Cell Carcinoma via mTOR /AKT/ERK1/2 pathway. Phytomedicine, 130, 11 pages.
DOI Scopus15 WoS14 Europe PMC12
2023 Thankamony, A. P., Ramkomuth, S., Ramesh, S. T., Murali, R., Chakraborty, P., Karthikeyan, N., . . . Nair, R. (2023). Phenotypic heterogeneity drives differential disease outcome in a mouse model of triple negative breast cancer. Frontiers in Oncology, 13, 13 pages.
DOI Scopus9 WoS7 Europe PMC7
2023 Jayalekshmi, V. S., Jaikumar, V. S., Mehra, P., Thulaseedharan, T., Vinod, V. M., & Ramachandran, S. (2023). Differential expression of lipid metabolic genes in hypercholesterolemic rabbit placenta predisposes the offspring to develop atherosclerosis in early adulthood. Life Sciences, 327, 15 pages.
DOI Scopus4 WoS4 Europe PMC3
2023 Richard, V., Nair, M. G., Jaikumar, V. S., Jones, S., Prabhu, J. S., & Kerin, M. J. (2023). Cell State Transitions and Phenotypic Heterogeneity in Luminal Breast Cancer Implicating MicroRNAs as Potential Regulators. International Journal of Molecular Sciences, 24(4), 3497.
DOI Scopus6 Europe PMC7
2023 Vini, R., Jaikumar, V. S., Remadevi, V., Ravindran, S., Azeez, J. M., Sasikumar, A., . . . Sreeja, S. (2023). Urolithin A: A promising selective estrogen receptor modulator and 27-hydroxycholesterol attenuator in breast cancer. Phytotherapy Research, 37(10), 4504-4521.
DOI Scopus11 WoS9 Europe PMC10
2023 Varghese, G. R., Patra, D., Jaikumar, V. S., Rajan, A., Latha, N. R., & Srinivas, P. (2023). βhCG mediates immune suppression through upregulation of CD11b+Gr1+ myeloid derived suppressor cells, CD206+ M2 macrophages, and CD4+FOXP3+ regulatory T-cells in BRCA1 deficient breast cancers. Immunology, 170(2), 270-285.
DOI Scopus6 WoS7 Europe PMC5
2022 Riya, P. A., Basu, B., Surya, S., Parvathy, S., Lalitha, S., Jyothi, N. P., . . . James, J. (2022). HES1 promoter activation dynamics reveal the plasticity, stemness and heterogeneity in neuroblastoma cancer stem cells. Journal of Cell Science, 135(22), 16 pages.
DOI Scopus15 WoS16 Europe PMC13
2022 Wanjale, M. V., Jaikumar, V. S., Sivakumar, K. C., Paul, R. A., James, J., & Kumar, G. S. V. (2022). Supramolecular Hydrogel Based Post-Surgical Implant System for Hydrophobic Drug Delivery Against Glioma Recurrence. International Journal of Nanomedicine, 17, 2203-2224.
DOI Scopus27 WoS25 Europe PMC19
2021 Mukesh, R. K., Kalam, A. A., Nag, J., Jaikumar, V. S., Kunnakkadan, U., Kumar, N. A., . . . Johnson, J. B. (2021). Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo. Molecular Therapy Oncolytics, 23, 254-265.
DOI Scopus6 WoS6 Europe PMC6
2020 Narendrakumar, L., Jaikumar, V. S., Chandrika, S. K., & Thomas, S. (2020). Epidemiological and pathogenic characteristics of Haitian variant V. cholerae circulating in India over a decade (2000–2018). Microbial Pathogenesis, 149, 10 pages.
DOI Scopus3 WoS3 Europe PMC3

Year Citation
2025 Padmaja, K. P., Mohan, A., Nair, M., Prabhu, J., Shabeer, H., Snijesh, V. P., . . . Maliekal, T. T. (2025). TIF1γ drives oral cancer recurrence by the transcriptional regulation of self-renewal genes, such as <i>HES1</i>.
DOI
2024 Srinivas, P., Latha, N. R., Jaikumar, V. S., Varghese, G. R., Krithiga, K., Krishnan, N., . . . Patra, D. (2024). Targeting Ezrin Can Impede Transformation of Cancer Associated Fibroblast (Caf) to Metastasis Associated Fibroblasts (Maf) in Brca1 Defective Triple Negative Breast Cancers.
DOI
2024 Rayginia, T., Keerthana, C., Aiswarya, S., Shifana, S., Jannet, S., Varma, S. S., . . . Anto, R. J. (2024). Uttroside B, a US-FDA-Designated Orphan Drug Against Hepatocellular Carcinoma (HCC), Impedes Non-alcoholic Steatohepatitis (NASH) and NASH -Induced HCC.
DOI
2022 Thankamony, A., Murali, R., Chakraborty, P., Karthikeyan, N., Varghese, B. A., Jaikumar, V. S., . . . Nair, R. (2022). Phenotypic Heterogeneity Drives Differential Disease Outcome in Triple Negative Breast Cancer.
DOI
2022 Nair, M., Apoorva, D., Chandrakala, M., Snijesh, V. P., Anupama, C. E., Rajarajan, S., . . . Prabhu, J. (2022). Acquisition of hybrid E/M phenotype associated with increased migration, drug resistance and stemness is mediated by reduced miR-18a levels in ER-negative breast cancer.
DOI Europe PMC1
2022 Patra, D., Varghese, G. R., Jaikumar, V. S., Rajan, A., Krishnan, N., Kuppuswamy, K., . . . Srinivas, P. (2022). BRCA1 Hypermethylation In Sporadic Breast Cancers: Discovering A Novel Pathway To Tumorigenesis Via Coordinate NBR2 Deregulation And TNBC Transformation.
DOI

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