Vicky Staikopoulos

Laboratory Manager - RA

Adelaide Medical School

Faculty of Health and Medical Sciences

Vicky Staikopoulos.

Vicky is currently working as a post-doc within the Neuroimmunopharmacology Laboratory (School Medicine/ Faculty Health Sciences), headed by supervisor Prof. Mark Hutchinson. Vicky is also a member of the ARC Centre of Excellence for Nanoscale Biophotonics (Origins of Sensations biological theme).

Title of her PhD research project is: The role of nitroxyl (HNO) in neuropathic pain signalling and development of morphine tolerance.

Prior to starting her PhD, Vicky worked in a similar capacity within various labs from the Universities of Adelaide and Melbourne for the last 16 years.

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Vicky Staikopoulos is a Early Career Researcher within the Adelaide Medical School and a member of the ARC Centre of Excellence for Nanoscale BioPhotonics.

Dr Staikopoulos returned to the University of Adelaide in 2010 as a Research Assistant with Associate Professor Elizabeth Beckett's team before joining the Neuroimmunopharmacology research laboratory, headed by Prof Mark Hutchinson, in 2012. From 2003 to 2010 Vicky worked in the Department of Anatomy and Cell Biology under Prof John Furness and Drs Ernie Jennings and Martin Stebbing at the University of Melbourne, Victoria. Here she worked on projects focused on understanding neural mechanisms driving migraine and chronic pain within the central nervous system.

Vicky's work has contributed to several journal publications and referred conference proceedings on various areas of research.

After many years working as a Research Assistant providing support and training to students and teaching laboratory techniques ranging from small animal surgeries to immunofluorescent staining and imaging, Vicky enrolled in a PhD research program with Prof Mark Hutchinson and A/Prof Elizabeth Beckett. The research carried out during this time was done in collaboration with Chemists, Physicists and Biologists based locally, interstate and overseas who are part of the broader CNBP community.

Her thesis titled: "The role of nitroxyl in the development of neuropathic pain" was completed in 2019.

Vicky currently works with Prof Robert McLaughlin and his Miniprobes team based at the University of Adelaide.

Appointments

Date	Position	Institution name
2011 - 2020	Research Associate	University of Adelaide
2003 - 2010	Research Assistant	University of Melbourne
1999 - 2003	Research Assistant	University of Adelaide

Language Competencies

Language Competency

Greek, Modern (1453-) Can read, write, speak and understand spoken

Language	Competency
Greek, Modern (1453-)	Can read, write, speak and understand spoken

Education

Date	Institution name	Country	Title
2016 - 2020	University of Adelaide	Australia	PhD
2003 - 2004	Monash University	Australia	Graduate Certificate - Secondary Education
1997 - 2000	University of Adelaide	Australia	BSc (Honours)

Research Interests

Animal Physiology - Cell Animal Physiology _ Systems Medical Physiology Physiology

Journals

Year	Citation
2020	Doyle, T. M., Largent-Milnes, T. M., Chen, Z., Staikopoulos, V., Esposito, E., Delgarno, R., . . . Salvemini, D. (2020). Chronic morphine-induced changes in signaling at the A3 adenosine receptor contribute to morphine-induced hyperalgesia, tolerance and withdrawal.. The Journal of pharmacology and experimental therapeutics, 374(2), 331-341. DOI Scopus5 WoS3
2020	Doyle, T. M., Hutchinson, M. R., Braden, K., Janes, K., Staikopoulos, V., Chen, Z., . . . Salvemini, D. (2020). Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents. Journal of Neuroinflammation, 17(1), 8 pages. DOI
2020	Staikopoulos, V., Qiao, S., Liu, J., Song, X., Yang, X., Luo, Q., . . . Zhang, Z. (2020). Graded peripheral nerve injury creates mechanical allodynia proportional to the progression and severity of microglial activity within the spinal cord of male mice. Brain, Behavior, and Immunity, 91, 568-577. DOI
2019	Grundy, L., Harrington, A., Caldwell, A., Castro, J., Staikopoulos, V., Zagorodnyuk, V., . . . Brierley, S. (2019). Translating peripheral bladder afferent mechanosensitivity to neuronal activation within the lumbosacral spinal cord of mice. Pain, 160(4), 793-804. DOI Scopus5 WoS6 Europe PMC1
2019	Parker, L. M., Sayyadi, N., Staikopoulos, V., Shrestha, A., Hutchinson, M. R., & Packer, N. H. (2019). Visualizing neuroinflammation with fluorescence and luminescent lanthanide-based in situ hybridization. Journal of Neuroinflammation, 16(1), 65-1-65-13. DOI Scopus3 WoS3 Europe PMC1
2018	Beckett, E., Staikopoulos, V., & Hutchinson, M. (2018). Differential effect of morphine on gastrointestinal transit, colonic contractions and nerve-evoked relaxations in Toll-Like Receptor deficient mice. Scientific Reports, 8(1), 5923-1-5923-13. DOI Scopus5 WoS5 Europe PMC2
2016	Jacobsen, J., Parker, L., Everest-Dass, A., Schartner, E., Tsiminis, G., Staikopoulos, V., . . . Mustafa, S. (2016). Novel imaging tools for investigating the role of immune signalling in the brain. Brain, Behavior, and Immunity, 58, 40-47. DOI Scopus9 WoS9 Europe PMC2
2016	Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I., . . . Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15(6), 1376-1386. DOI Scopus43 WoS40 Europe PMC17
2016	Grace, P., Gaudet, A., Staikopoulos, V., Maier, S., Hutchinson, M., Salvemini, D., & Watkins, L. (2016). Nitroxidative signaling mechanisms in pathological pain. Trends in Neurosciences, 39(12), 862-879. DOI Scopus37 WoS31 Europe PMC16
2015	Lee, S., Hutchinson, M., Staikopoulos, V., & Saint, D. (2015). Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury. International Journal of Cardiology, 190, 353-359. DOI Scopus7 WoS6 Europe PMC5
2015	Dodds, K., Staikopoulos, V., & Beckett, E. (2015). Uterine contractility in the nonpregnant mouse: changes during the estrous cycle and effects of chloride channel blockade. Biology of Reproduction, 92(6), 141-1-141-15. DOI Scopus19 WoS17 Europe PMC11
2013	Spencer, N., Nicholas, S., Sia, T., Staikopoulos, V., Kyloh, M., & Spencer, E. (2013). By what mechanism does ondansetron inhibit colonic migrating motor complexes: does it require endogenous serotonin in the gut wall?. Neurogastroenterology and Motility, 25(8), 677-685. DOI Scopus19 WoS18 Europe PMC14
2012	Jennings, E. A., Williams, M. C., Staikopoulos, V., & Ivanusic, J. J. (2012). Neurobiology of Temporomandibular Joint Pain: Therapeutic Implications. Seminars in Orthodontics, 18(1), 63-72. DOI Scopus1
2011	Ivanusic, J., Beaini, D., Hatch, R., Staikopoulos, V., Sessle, B., & Jennings, E. (2011). Peripheral N-methyl-ᴅ-aspartate receptors contribute to mechanical hypersensitivity in a rat model of inflammatory temporomandibular joint pain. European Journal of Pain, 15(2), 179-185. DOI Scopus18 Europe PMC19
2009	Cho, H., Staikopoulos, V., Furness, J., & Jennings, E. (2009). Inflammation-induced increase in hyperpolarization-activated, cyclic nucleotide-gated channel protein in trigeminal ganglion neurons and the effect of buprenorphine. Neuroscience, 162(2), 453-461. DOI Scopus33 Europe PMC25
2009	Weston, R., Subasinghe, K., Staikopoulos, V., & Jarrott, B. (2009). Design and Assessment of a Potent Sodium Channel Blocking Derivative of Mexiletine for Minimizing Experimental Neuropathic Pain in Several Rat Models. Neurochemical Research, 34(10), 1816-1823. DOI Scopus8 Europe PMC6
2009	Cho, H., Staikopoulos, V., Ivanusic, J., & Jennings, E. (2009). Hyperpolarization-activated cyclic-nucleotide gated 4 (HCN4) protein is expressed in a subset of rat dorsal root and trigeminal ganglion neurons. Cell and Tissue Research, 338(2), 171-177. DOI Scopus20 Europe PMC16
2008	Janovska, A., Hatzinikolas, G., Staikopoulos, V., McInerney, J., Mano, M., & Wittert, G. (2008). AMPK and ACC phosphorylation: Effect of leptin, muscle fibre type and obesity. Molecular and Cellular Endocrinology, 284(1-2), 1-10. DOI Scopus37 WoS34 Europe PMC22
2008	Albanese, V., Lawson, V., Hill, A., Cappai, R., Di Guardo, G., Staikopoulos, V., . . . Chiocchetti, R. (2008). Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine. Autonomic Neuroscience-Basic & Clinical, 140(1-2), 17-23. DOI Scopus21 Europe PMC14
2007	Staikopoulos, V., Sessle, B., Furness, J., & Jennings, E. (2007). Localization of P2X2 and P2X3 receptors in rat trigeminal ganglion neurons. Neuroscience, 144(1), 208-216. DOI Scopus79 Europe PMC58
2005	Hind, A., Migliori, M., Thacker, M., Staikopoulos, V., Nurgali, K., Chiocchetti, R., & Furness, J. (2005). Primary afferent neurons intrinsic to the guinea-pig intestine, like primary afferent neurons of spinal and cranial sensory ganglia, bind the lectin, IB4. Cell and Tissue Research, 321(2), 151-157. DOI Scopus21 Europe PMC15

Conference Papers

Year	Citation
2016	Staikopoulos, V., Gosnell, M., Anwer, A., Mustafa, S., Hutchinson, M., & Goldys, E. (2016). Hyperspectral imaging of endogenous fluorescent metabolic molecules to identify pain states in central nervous system tissue. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 1-8). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI Scopus2 WoS1
2015	Dodds, K., Beckett, E., Staikopoulos, V., Evans, S., & Hutchinson, M. (2015). Novel mouse model of endometriosis permits identification of spinal glia and nociception characteristics involved in pelvic pain. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 267). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	Staikopoulos, V., Jin, D., Lu, Y., Gibson, B., Reineck, P., Goldys, E., . . . Hutchinson, M. (2015). Ultra-structural imaging in cleared mouse cns using nanoparticles. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 382). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	Jacobsen, J., Staikopoulos, V., & Hutchinson, M. (2015). Optimisation and utilisation of a novel whole-brain imaging technique (clarity) to analyse addiction-like behaviours. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 351). Cairns, AUSTRALIA: WILEY-BLACKWELL.

Conference Items

Year	Citation
2020	Rolan, P., Dodds, K., Lees, F., Staikopoulos, V., Gosnell, M., Goldys, E., & Hutchinson, M. (2020). TWO NOVEL BIOMARKERS FOR MIGRAINE IN PERIPHERAL BLOOD MONONUCLEAR CELLS. Poster session presented at the meeting of CEPHALALGIA. ELECTR NETWORK: SAGE PUBLICATIONS LTD.

Work carried out during this PhD is being funded by an Australian Postgraduate Award and the ARC Centre of Excellence for Nanoscale Biophotonics.

APA

cnbp

http://www.cnbp.org.au/

Committee Memberships

Date	Role	Committee	Institution	Country
2016 - ongoing	Representative	ARC CNBP Executive Memebers Committee	University of Adelaide	Australia
2016 - ongoing	Representative	ANS Student Body	Australiasian Neuroscience Society	Australia

Memberships

Date Role Membership Country

2015 - ongoing Member Society of Neuroscience United States

2015 - ongoing Member Australasian Neuroscience Society Australia

Date	Role	Membership	Country
2015 - ongoing	Member	Society of Neuroscience	United States
2015 - ongoing	Member	Australasian Neuroscience Society	Australia

Position: Laboratory Manager - RA
Phone: 83134566
Email: vicky.staikopoulos@adelaide.edu.au
Campus: North Terrace
Building: Helen Mayo South, floor S5
Room: S5 13A
Org Unit: Faculty of Health and Medical Sciences

Vicky Staikopoulos

Appointments

Language Competencies

Education

Research Interests

Journals

Conference Papers

Conference Items

http://www.cnbp.org.au/

Committee Memberships

Memberships

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