Tracy Fitzsimmons

Dr Tracy Fitzsimmons

NHMRC Postdoctoral Researcher

Adelaide Dental School

Faculty of Health and Medical Sciences


My studies focus on the host cell immune and inflammatory response to microbial infection associated with periodontal disease, specifically Porphyromonas gingivalis.  In addition, a key area of interest is exploring the relationship between periodontitis and systemic diseases such as rheumatoid arthritis in terms of adjunct therapy to standard treatment regimes.  I have extensive experience relating to detection and quantification of inflammatory mediators locally in the oral cavity, gums and tissues, particularly gingival crevicular fluid (GCF) utilising multiplex and ELISA's in addition to a number of molecular biology techniques and cell culture.

 

Date Project Title Investigators Funding Body Amount
2018 Barbara Kidman Women's Fellowship TR Fitzsimmons University of Adelaide $24,000
2017 Azithromycin modulation of cytokine production during LPS induced/chronic inflammation in vitro:  Impact on osteoclastogenesis TR Fitzsimmons, D Haynes, PM Bartold Australian Dental Research Foundation $11,050
2014 Cytokine profiles in serum and placenta of pregnant mice following experimentally induced periodontitis P Zilm, TR Fitzsimmons, C Roberts.  Australian Dental Research Foundation $13,764
2014 Fish oil as an adjunct therapy for periodontitis – a pilot study to determine whether there are acute and chronic benefits? A Coates, TR Fitzsimmons, PM Bartold, S Ivanovski, P Howe Australian Dental Research Foundation $9000
2012 Effect of Azithromycin on cytokine expression by human gingival fibroblasts C Doyle, Bartold PM, TR Fitzsimmons, C Marchant Australian Dental Research Foundation $6000
2010 Multiplex analysis of the presence of IL-13, IL-15 and IL-17 in gingival crevicular fluid of subjects with periodontitis TR Fitzsimmons Australian Dental Research Foundation $5600
2009 A NanoDrop spectrophotometer system for micro-volume quantitation of nucleic acid and protein TR Fitzsimmons, PS Zilm, PM Bartold, P Cathro, D Haynes, S Gronthos, T Hughes, G Townsend, D Keefe National Health and Medical Research Council, Equipment Grant $10,000
2009 Identification and quantitation of periodontal pathogens by real-time polymerase chain reaction TR McNamara, N Gully, PS Zilm Australian Dental Research Foundation $4000
2009 The effects of environmental redox potential (Eh) and pH on Fusobacterium nucleatum and Porphyromonas gingivalis co-cultured biofilms J Chew, N Gully, PS Zilm, TR McNamara Australian Dental Research Foundation $4000
2009 An in-vitro evaluation of the effectiveness of endodontic irrigants, with and without ultrasonic activation, in the eradication of Enterococcus faecalis biofilm A Seet, P Cathro, PS Zilm, TR McNamara, N Gully Australian Dental Research Foundation $4000
2009 Efficacy of antimicrobial treatment involving sodium hypochlorite, ledermix and calcium hydroxide against Enterococcus faecalis cultured as a biofilm on a dentine substrate PS Zilm, P Cathro, B Plutzer, TR McNamara Australian Dental Research Foundation $4000
2008 Influence of smoking on molecules associated with bone resorption in human gingival crevicular fluid.  Australian Dental Research Foundation PM Bartold, TR McNamara, T Tang Australian Dental Research Foundation $6600
2007 Investigation of proteins in gingival crevicular fluid as a basis for disease diagnosis T McNamara, P Zilm, C Bagley, PM Bartold Australian Dental Research Foundation $4800

 

Dates Teaching Role Course School, Faculty, Institution Subject Code
Semester 1, 2009 Casual Tutor Human Biology ID Part 1 School of Dentistry, Faculty of Health Sciences, University of Adelaide 2910_DENT_1003AHO
Semester 2, 2008 Casual Tutor Dental and Health Science II Part 2 School of Dentistry, Faculty of Health Sciences, University of Adelaide 2620_DENT_2001BHO
Semester 2, 2006 Casual Ttor Dental and Health Science II Part 2 School of Dentistry, Faculty of Health Sciences, University of Adelaide 2620_DENT_2001BHO

 

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  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2018 - ongoing Principal Supervisor Oral microbiome assessment of plaque biofilms in an in vitro 3D printed flow cell Adelaide Dental School, University of Adelaide Honours Full Time Peter Varga
    2018 - ongoing Principal Supervisor Benefits of omega-3 fatty acids and their derivatives in periodontitis and rheumatoid arthritis Adelaide Dental School, University of Adelaide Honours Part Time Lucas Ciacciarelli
    2018 - ongoing Co-Supervisor Regulation of osteoimmune immunoreceptor tyrosine-based activation motif (ITAM) signalling factors in the pathogenesis of Chronic Periodontitis Adelaide Medical School, University of Adelaide Honours Full Time Adrian Duran
    2017 - 2017 Principal Supervisor Azithromycin modulation of cytokine production during LPS induced/chronic inflammation in vitro: Impact on osteoclastogenesis Adelaide Dental School, University of Adelaide Honours Full Time Dr Alen Rahulan
    2011 - 2013 Co-Supervisor Azithromycin suppresses P. gingivalis LPS induced pro-inflammatory cytokine and chemokine production (IL-6, IL-8, MCP-1 and GRO) by human gingival fibroblasts in vitro Dept of Dentistry, University of Adelaide Doctor of Clinical Dentistry (Periodontics) Other Dr Catherine Doyle
    2009 - 2011 Co-Supervisor Expression of bone resorption markers in gingival crevicular fluid of rheumatoid arthritis patients with and without periodontitis: a pilot study’ Dept of Dentistry, University of Adelaide Doctor of Clinical Dentistry (Periodontics) Other Dr Kere Kobayashi
    2009 - 2011 Co-Supervisor Expression of rheumatoid arthritis markers in normal and inflamed gingival tissues Dept of Dentistry, University of Adelaide Doctor of Clinical Dentistry (Periodontics) Other Dr Geoffrey Harvey
    2009 - 2010 Co-Supervisor C-reactive protein, periodontitis and systemic inflammation Dept of Dentistry, University of Adelaide Doctor of Clinical Dentistry (Periodontics) Other Dr Emma Megson
    2007 - 2009 Co-Supervisor C-reactive protein, periodontitis and systemic inflammation Dept of Dentistry, University of Adelaide Doctor of Clinical Dentistry (Periodontics) Other Dr Teck Tang
  • Position: NHMRC Postdoctoral Researcher
  • Phone: 83135677
  • Email: tracy.fitzsimmons@adelaide.edu.au
  • Fax: 8313 6429
  • Campus: North Terrace
  • Building: Helen Mayo South, floor 3
  • Room: 3 21
  • Org Unit: Colgate

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