Tom Gonda

Prof Tom Gonda

Research Professor

Centre for Cancer Biology

College of Health

Available For Media Comment.

Professor Tom GondaBSc (Hons) Adel., PhD Adel. Research Leader, Cancer BiologyBiography:Professor Tom Gonda carried out postdoctoral research from 1979-81 at the University of California, San Francisco in the laboratory of Nobel Laureate Professor J Michael Bishop. This position started Professor Gonda’s continuing interest in leukaemia and the myb oncogene. He returned to Australia in 1982 as a Research Fellow at the Ludwig Institute for Cancer Research, Melbourne, where he expanded his research to include retroviral vectors, cytokines and leukaemia. He returned to Adelaide in 1990 as an NHMRC Research Fellow at the Hanson Centre for Cancer Research. In 2001 he tried his hand at biotechnology as Chief Scientist, Bionomics Ltd, Adelaide, where he directed the company’s research and development programs. In 2003 he returned to academia in his current position at the Diamantina Institute. He has been a member of ARC and NHMRC grant review panels and involved in the organisation of a number of scientific conferences.Research Interests:Professor Gonda’s major research interest is in identifying and characterising oncogenes involved in major human cancers – particularly leukaemia and breast cancer. His work has a particular focus on the MYB oncogene, which is a key player in normal haemopoiesis and leukaemia. He has also been extensively involved in work on cytokines and their receptors. The other main focus of Professor Gonda’s work has been the development and application of functional gene discovery using retroviral vectors. His work has a long-term goal not only to enhance understanding of cancer but also to apply the results to developing novel cancer therapeutics.Research Projects:Identification and Characterisation of MYB target genesApproaches to therapeutic targeting of MYB in leukaemia and other cancersRole of MYB in human breast cancerTranscriptional regulation of MYB expressionMyeloid leukaemia gene discoveryDevelopment and application of high-throughput retroviral expression cloning – the ARVEC initiative.

Year Citation
2025 Liu, L., Glaser, A., Isiaku, A. I., Fairfax, K., Casolari, D. A., Ristovski, A., . . . Deans, A. J. (2025). Fancl-mutant mice reveal central role of monoubiquitination in Fanconi anemia and a model for therapeutic gene editing.. Blood advances, bloodadvances.2025017217.
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2023 Gonda, T. J. (2023). MYB deficiency leads to myeloid neoplasia too. Blood, 141(15), 1786-1787.
DOI Scopus1 WoS1 Europe PMC1
2022 Bassal, M. A., Samaraweera, S. E., Lim, K., Bernard, B. A., Bailey, S., Kaur, S., . . . D'Andrea, R. J. (2022). Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia. Nature Communications, 13(1), 1-12.
DOI Scopus18 WoS19 Europe PMC16
2022 Bassal, M. A., Samaraweera, S. E., Lim, K., Benard, B. A., Bailey, S., Kaur, S., . . . D'Andrea, R. J. (2022). Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.. Nat Commun, 13(1), 4131.
DOI Scopus2 WoS2 Europe PMC1
2022 Hannan, K. M., Soo, P., Wong, M. S., Lee, J. K., Hein, N., Poh, P., . . . George, A. J. (2022). Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway. Cell Reports, 41(5), 111571.
DOI Scopus33 Europe PMC42
2021 Yusenko, M. V., Trentmann, A., Casolari, D. A., Abdel Ghani, L., Lenz, M., Horn, M., . . . Klempnauer, K. H. (2021). C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia. Oncogene, 40(29), 4746-4758.
DOI Scopus20 WoS16 Europe PMC14
2021 Samaraweera, S. E., Wang, P. P. S., Li, K. L., Casolari, D. A., Feng, J., Maung, K. Z. Y., . . . D'Andrea, R. J. (2021). Childhood acute myeloid leukemia shows a high level of germline predisposition. Blood, 138(22), 2293-2298.
DOI Scopus11 WoS9 Europe PMC9
2019 Yang, R. M., Nanayakkara, D., Kalimutho, M., Mitra, P., Khanna, K. K., Dray, E., & Gonda, T. J. (2019). MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells. Oncogene, 38(26), 5239-5249.
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2019 Cao, L., Mitra, P., & Gonda, T. J. (2019). The mechanism of MYB transcriptional regulation by MLL-AF9 oncoprotein. Scientific reports, 9(1, article no. 20084), 1-11.
DOI Scopus11 WoS9 Europe PMC7
2018 Artuz, C. M., Knights, A. J., Funnell, A. P. W., Gonda, T. J., Ravid, K., Pearson, R. C. M., . . . Crossley, M. (2018). Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules. Biotechnology Reports, 20(e00285), e00285-1-e00285-4.
DOI Scopus3 Europe PMC2
2018 Jamaludin, S. Y. N., Azimi, I., Davis, F. M., Peters, A. A., Gonda, T. J., Thompson, E. W., . . . Monteith, G. R. (2018). Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells. Oncology letters, 15(4), 4289-4295.
DOI Scopus8 WoS6 Europe PMC5
2018 Maung, K. Z. Y., Leo, P. J., Bassal, M., Casolari, D. A., Gray, J. X., Bray, S. C., . . . Gonda, T. J. (2018). Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia. Blood Cancer Journal, 8(6), 50-1-50-5.
DOI Scopus16 WoS16 Europe PMC13
2017 Peters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Gonda, T. J., & Monteith, G. R. (2017). Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells. Oncogene, 36(46), 6490-6500.
DOI Scopus77 WoS70 Europe PMC66
2017 Lee, W. J., Škalamera, D., Dahmer Heath, M., Shakhbazov, K., Ranall, M. V., Fox, C., . . . Gabrielli, B. (2017). Genome-wide overexpression screen identifies genes able to bypass p16-mediated senescence in melanoma. SLAS discovery, 22(3), 298-308.
DOI Scopus10 WoS11 Europe PMC9
2017 Worton, L., Shi, Y. -C., Smith, E., Barry, S., Gonda, T., Whitehead, J., & Gardiner, E. (2017). Ectodermal-neural cortex 1 isoforms have contrasting effects on MC3T3-E1 osteoblast mineralization and gene expression. Journal of Cellular Biochemistry, 118(8), 2141-2150.
DOI Scopus7 WoS7 Europe PMC8
2016 Škalamera, D., Dahmer-Heath, M., Stevenson, A. J., Pinto, C., Shah, E. T., Daignault, S. M., . . . Gonda, T. J. (2016). Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. Oncotarget, 7(38), 61000-61020.
DOI Scopus9 WoS9 Europe PMC6
2016 Mitra, P., Yang, R. M., Sutton, J., Ramsay, R. G., & Gonda, T. J. (2016). CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression. Oncotarget, 7(8), 9069-9083.
DOI Scopus43 WoS41 Europe PMC40
2016 Gonda, T. J., & Ramsay, R. G. (2016). Adenoid cystic carcinoma can be driven by MYB or MYBL1 rearrangements: new insights into MYB and tumor biology. Cancer discovery, 6(2), 125-127.
DOI Scopus24 WoS22 Europe PMC20
2015 Gonda, T. J., & Ramsay, R. G. (2015). Directly targeting transcriptional dysregulation in cancer. Nature reviews cancer, 15(11), 686-694.
DOI Scopus88 WoS86 Europe PMC85
2015 Pereira, L. A., Hugo, H. J., Malaterre, J., Huiling, X., Sonza, S., Cures, A., . . . Ramsay, R. G. (2015). MYB elongation is regulated by the nucleic acid binding of NFekB p50 to the intronic stem-loop region. PLoS ONE, 10(4, article no. e0122919), 1-25.
DOI Scopus11 WoS11 Europe PMC11
2015 Gagoski, D., Mureev, S., Giles, N., Johnston, W., Dahmer-Heath, M., Škalamera, D., . . . Alexandrov, K. (2015). Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems. Journal of Biotechnology, 195, 1-7.
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2015 Gabrielli, B., Bokhari, F., Ranall, M. V., Oo, Z. Y., Stevenson, A. J., Wang, W., . . . McMillan, N. A. J. (2015). Aurora A is critical for survival in HPV-transformed cervical cancer. Molecular cancer therapeutics, 14(12), 2753-2761.
DOI Scopus31 WoS33 Europe PMC31
2014 Sierecki, E., Stevers, L. M., Giles, N., Polinkovsky, M. E., Moustaqil, M., Mureev, S., . . . Gambin, Y. (2014). Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by alphascreen and single-molecule spectroscopy. Molecular and cellular proteomics, 13(9), 2233-2245.
DOI Scopus34 WoS35 Europe PMC34
2014 Pattabiraman, D. R., McGirr, C., Shakhbazov, K., Barbier, V., Krishnan, K., Mukhopadhyay, P., . . . Gonda, T. J. (2014). Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes. Blood, 123(17), 2682-2690.
DOI Scopus106 WoS101 Europe PMC97
2014 Brooks, K., Ranall, M., Spoerri, L., Stevenson, A., Gunasingh, G., Pavey, S., . . . Gabrielli, B. (2014). Decatenation checkpoint-defective melanomas are dependent on PI3K for survival. Pigment Cell and Melanoma Research, 27(5), 813-821.
DOI Scopus11 WoS11 Europe PMC8
2014 Zhao, L., Ye, P., & Gonda, T. J. (2014). The MYB proto-oncogene suppresses monocytic differentiation of acute myeloid leukemia cells via transcriptional activation of its target gene GFI1. Oncogene, 33(35), 4442-4449.
DOI Scopus31 WoS29 Europe PMC30
2014 Ye, P., Zhao, L., McGirr, C., & Gonda, T. J. (2014). MYB down-regulation enhances sensitivity of U937 myeloid leukemia cells to the histone deacetylase inhibitor LBH589 in vitro and in vivo. Cancer letters, 343(1), 98-106.
DOI Scopus14 WoS13 Europe PMC12
2014 Zhao, L., Pattabiraman, D. R., & Gonda, T. J. (2014). MYB (v-myb myeloblastosis viral oncogene homolog (avian)). Atlas of Genetics and Cytogenetics in Oncology and Haematology, 14(1), 36-38.
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2013 Ye, P., Zhao, L., & Gonda, T. J. (2013). The MYB oncogene can suppress apoptosis in acute myeloid leukemia cells by transcriptional repression of DRAK2 expression. Leukemia research, 37(5), 595-601.
DOI Scopus20 WoS21 Europe PMC19
2013 Hugo, H. J., Pereira, L., Suryadinata, R., Drabsch, Y., Gonda, T. J., Gunasinghe, N. P. A. D., . . . Thompson, E. W. (2013). Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells. Breast cancer research, 15(6), 1-19.
DOI Scopus62 WoS61 Europe PMC60
2013 Pattabiraman, D. R., & Gonda, T. J. (2013). Role and potential for therapeutic targeting of MYB in leukemia. Leukemia, 27(2), 269-277.
DOI Scopus113 WoS113 Europe PMC108
2012 Mitra, P., Pereira, L. A., Drabsch, Y., Ramsay, R. G., & Gonda, T. J. (2012). Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene. Nucleic acids research, 40(13), 5988-6000.
DOI Scopus40 WoS39 Europe PMC40
2012 Waddell, N., Stein, S. R., Wagner, S. A., Bennett, I., Djougarian, A., Melana, S., . . . Francis, G. D. (2012). Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong. Pathology, 44(5), 469-472.
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2012 Skalamera, D., Dahmer, M., Purdon, A. S., Wilson, B. M., Ranall, M. V., Blumenthal, A., . . . Gonda, T. J. (2012). Generation of a genome scale lentiviral vector library for EF1a promoter-driven expression of human ORFs and identification of human genes affecting viral titer. PLoS ONE, 7(12, article number e51733), 1-15.
DOI Scopus23 WoS23 Europe PMC19
2012 Mori, S., Bernardi, R., Laurent, A., Resnati, M., Crippa, A., Gabrieli, A., . . . Blasi, F. (2012). Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor. PLoS One, 7(10), e39723-1-e39723-14.
DOI Scopus37 WoS37 Europe PMC35
2012 Hochstatter, J., Hoelzel, M., Rohrmoser, M., Schermelleh, L., Leonhardt, H., Keough, R., . . . Nemeth, A. (2012). Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. Journal of Biological Chemistry, 287(29), 24365-24377.
DOI Scopus35 WoS36 Europe PMC34
2012 Brown, A., Salerno, D., Sadras, T., Engler, G., Kok, C., Wilkinson, C., . . . D'Andrea, R. (2012). The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation. Differentiation, 83(1), 47-59.
DOI Scopus23 WoS21 Europe PMC20
2011 Skalamera, D., Ranall, M., Wilson, B., Leo, P., Purdon, A., Hyde, C., . . . Gonda, T. (2011). A high-throughput platform for lentiviral overexpression screening of the human ORFeome. PLoS One, 6(5), e20057-1-e20057-14.
DOI Scopus41 WoS42 Europe PMC40
2011 Miao, R. Y., Drabsch, Y., Cross, R. S., Cheasley, D., Carpinteri, S., Pereira, L., . . . Ramsay, R. G. (2011). MYB is essential for mammary tumorigenesis. Cancer research, 71(22), 7029-7037.
DOI Scopus54 WoS54 Europe PMC52
2011 Zhao, L., Glazov, E. A., Pattabiraman, D. R., Al Owaidi, F., Zhang, P., Brown, M. A., . . . Gonda, T. J. (2011). Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb. Nucleic acids research, 39(11), 4664-4679.
DOI Scopus81 WoS79 Europe PMC82
2011 Ranall, M. V., Gabrielli, B. G., & Gonda, T. J. (2011). High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene. BioTechniques, 51(1), 35-42.
DOI Scopus27 WoS24 Europe PMC21
2011 Dredge, K., Hammond, E., Handley, P., Gonda, T. J., Smith, M. T., Vincent, C., . . . Bytheway, I. (2011). PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models. British journal of cancer, 104(4), 635-642.
DOI Scopus164 WoS153 Europe PMC130
2011 Sæther, T., Pattabiraman, D. R., Alm Kristiansen, A. H., Vogt Kielland, L. T., Gonda, T. J., & Gabrielsen, O. S. (2011). A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability. Oncogene, 30(2), 212-222.
DOI Scopus24 WoS23 Europe PMC20
2011 Bender, T. P., Gonda, T. J., Frampton, J., Ness, S. A., & Ramsay, R. G. (2011). Professor Alan M Gewirtz (1949-2010) OBITUARY. ONCOGENE, 30(19), 2187.
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2010 Papathanasiou, P., Tunningley, R., Pattabiraman, D. R., Ye, P., Gonda, T. J., Whittle, B., . . . Perkins, A. C. (2010). A recessive screen for genes regulating hematopoietic stem cells. Blood, 116(26), 5849-5858.
DOI Scopus24 WoS22 Europe PMC23
2010 Drabsch, Y., Ramsay, R. G., & Gonda, T. J. (2010). MYB suppresses differentiation and apoptosis of human breast cancer cells. Breast cancer research, 12(4), 1-17.
DOI Scopus55 WoS54 Europe PMC49
2010 Ranall, M. V., Gabrielli, B. G., & Gonda, T. J. (2010). Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening. BioTechniques, 48(5), 379-386.
DOI Scopus14 WoS12 Europe PMC9
2010 Dredge, K., Hammond, E., Davis, K., Li, C. P., Liu, L., Johnstone, K., . . . Bytheway, I. (2010). The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy. Investigational new drugs, 28(3), 276-283.
DOI Scopus101 WoS93 Europe PMC83
2010 Johnstone, K. D., Karoli, T., Liu, L., Dredge, K., Copeman, E., Li, C. P., . . . Ferro, V. (2010). Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. Journal of medicinal chemistry, 53(4), 1686-1699.
DOI Scopus69 WoS67 Europe PMC50
2010 Brown, C., Sadlon, T., Gargett, T., Melville, E., Zhang, R., Drabsch, Y., . . . Barry, S. (2010). Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector. Human Gene Therapy, 21(8), 1005-1017.
DOI Scopus27 WoS28 Europe PMC24
2010 Fuller, H., Nguyen, T., Lam, L., Thanh, L., Keough, R., Asperger, A., . . . Morris, G. (2010). The SMN interactome includes Myb-binding protein 1a. Journal of Proteome Research, 9(1), 556-563.
DOI Scopus27 WoS27 Europe PMC23
2010 Perugini, M., Brown, A., Salerno, D., Booker, G., Stojkoski, C., Hercus, T., . . . D'Andrea, R. (2010). Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit. Blood, 115(16), 3346-3353.
DOI Scopus59 WoS52 Europe PMC45
2009 Perugini, M., Kok, C., Brown, A., Wilkinson, C., Salerno, D., Young, S., . . . D'Andrea, R. (2009). Repression of Gadd45α by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation. Leukemia, 23(4), 729-738.
DOI Scopus20 WoS19 Europe PMC21
2009 Ciznadija, D., Tothill, R., Waterman, M. L., Zhao, L., Huynh, D., Yu, R. M., . . . Malaterre, J. (2009). Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling. Cell death and differentiation, 16(11), 1530-1538.
DOI Scopus40 WoS38 Europe PMC35
2009 Pattabiraman, D. R., Sun, J., Dowhan, D. H., Ishii, S., & Gonda, T. J. (2009). Mutations in multiple domains of c-Myb disrupt interaction with CBP/p300 and abrogate myeloid transforming ability. Molecular cancer research, 7(9), 1477-1486.
DOI Scopus30 WoS30 Europe PMC29
2008 Drabsch, Y., Hugo, H., Zhang, R., Dowhan, D. H., Miao, Y. R., Gewirtz, A. M., . . . Gonda, T. J. (2008). Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, (13762-13767) DOI: 10.1073/pnas.0700104104). Proceedings of the National Academy of Sciences of the United States of America, 105(2), 825.
DOI Scopus1 WoS1
2008 Zhao, L., Neumann, B., Murphy, K., Silke, J., & Gonda, T. J. (2008). Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro. Blood cells, molecules, and diseases g, 41(2), 188-193.
DOI Scopus22 WoS17 Europe PMC19
2008 Ramsay, R. G., & Gonda, T. J. (2008). MYB function in normal and cancer cells. Nature reviews cancer, 8(7), 523-534.
DOI Scopus533 WoS510 Europe PMC475
2008 Gonda, T. J., Leo, P., & Ramsay, R. G. (2008). Estrogen and MYB in breast cancer: potential for new therapies. Expert opinion on biological therapy, 8(6), 713-717.
DOI Scopus37 WoS36 Europe PMC34
2008 Neumann, B., Zhao, L., Murphy, K., & Gonda, T. J. (2008). Subcellular localization of the Schlafen protein family. Biochemical and biophysical research communications, 370(1), 62-66.
DOI Scopus71 WoS66 Europe PMC66
2008 Yamauchi, T., Keough, R., Gonda, T., & Ishii, S. (2008). Ribosomal stress induces processing of Mybbp1a and its translocation from the nucleolus to the nucleoplasm. Genes to Cells, 13(1), 27-39.
DOI Scopus37 WoS38 Europe PMC34
2007 Drabsch, Y., Hugo, H., Zhang, R., Dowhan, D., Miao, Y., Gewirtz, A., . . . Gonda, T. (2007). Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 104(34), 13762-13767.
DOI Scopus114 WoS118 Europe PMC105
2006 Brown, A., Wilkinson, C., Waterman, S., Kok, C., Salerno, D., Diakiw, S., . . . D'Andrea, R. (2006). Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling. Journal of Leukocyte Biology, 80(2), 433-447.
DOI Scopus39 WoS37 Europe PMC39
2006 Lutwyche, J., Keough, R., Hunter, J., Coles, L., & Gonda, T. (2006). DNA binding-independent transcriptional activation of the vascular endothelial growth factor gene (VEGF) by the Myb oncoprotein. Biochemical and Biophysical Research Communications, 344(4), 1300-1307.
DOI Scopus13 WoS12 Europe PMC12
2006 Hugo, H., Cures, A., Suraweera, N., Drabsch, Y., Purcell, D., Mantamadiotis, T., . . . Ramsay, R. G. (2006). Mutations in the MYB intron 1 regulatory sequence increase transcription in colon cancers. Genes Chromosomes and Cancer, 45(12), 1143-1154.
DOI Scopus74 WoS75 Europe PMC66
2005 Phan, V. T., Shultz, D. B., Truong, B. T. H., Blake, T. J., Brown, A. L., Gonda, T. J., . . . Kogan, S. C. (2005). Erratum: Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation (Molecular and Cellular Biology (2003) 23, 13 (4573-4585)). Molecular and Cellular Biology, 25(13), 5787.
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2004 Tanikawa, J., Nomura, T., Macmillan, E. M., Shinagawa, T., Jin, W., Kokura, K., . . . Ishii, S. (2004). p53 suppresses c-myb-induced trans-activation and transformation by recruiting the corepressor mSin3A. Journal of Biological Chemistry, 279(53), 55393-55400.
DOI Scopus13 WoS12 Europe PMC12
2004 D'Andrea, R., Sadlon, T., & Gonda, T. (2004). Overlapping motifs in the membrane-proximal region of cytokine receptor accessory and signaling subunits. Cytokine & Growth Factor Reviews, 15(2-3), 83-85.
DOI Scopus3 WoS3 Europe PMC2
2004 Brown, A., Peters, M., D'Andrea, R., & Gonda, T. (2004). Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation. Blood, 103(2), 507-516.
DOI Scopus14 WoS16 Europe PMC11
2003 Vajjhala, P., Macmillan, E., Gonda, T., & Little, M. (2003). The Wilms' tumour suppressor protein, WT1, undergoes CRM1-independent nucleocytoplasmic shuttling. FEBS Letters, 554(1-2), 143-148.
DOI Scopus32 Europe PMC30
2003 Ferrao, P., Gonda, T., & Ashman, L. (2003). Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver. Leukemia Research, 27(6), 547-555.
DOI Scopus25 WoS24 Europe PMC22
2003 Bartley, P., Keough, R., Lutwyche, J., & Gonda, T. (2003). Regulation of the gene encoding glutathione S-transferase M1 (GSTM1) by the Myb oncoprotein. Oncogene, 22(48), 7570-7575.
DOI Scopus12 WoS12 Europe PMC11
2003 Keough, R., Macmillan, E., Lutwyche, J., Gardner, J., Tavner, F., Jans, D., . . . Gonda, T. (2003). Myb-binding protein 1a is a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways. Experimental Cell Research, 289(1), 108-123.
DOI Scopus22 WoS22 Europe PMC22
2003 Mourtada-Maarabouni, M., Kirkham, L., Jenkins, B., Rayner, J., Gonda, T., Starr, R., . . . Williams, G. (2003). Functional expression cloning reveals proapoptotic role for protein phosphatase 4. Cell Death and Differentiation, 10(9), 1016-1024.
DOI Scopus40 WoS39 Europe PMC36
2003 Ramsay, R. G., Barton, A. L., & Gonda, T. J. (2003). Targeting c-Myb expression in human disease. Expert Opinion on Therapeutic Targets, 7(2), 235-248.
DOI Scopus83 WoS79 Europe PMC66
2003 Phan, V., Shultz, D., Truong, B., Blake, T., Brown, A., Gonda, T., . . . Kogan, S. (2003). Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation. Molecular and Cellular Biology, 23(13), 4573-4585.
DOI Scopus12 WoS10 Europe PMC10
2002 Jones, L. C., Okino, S. T., Gonda, T. J., & Whitlock, J. P. (2002). Myb-binding protein 1a augments AhR-dependent gene expression. Journal of Biological Chemistry, 277(25), 22515-22519.
DOI Scopus34 WoS34 Europe PMC25
2002 Blake, T., Jenkins, B., D'Andrea, R., & Gonda, T. (2002). Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the β-subunit of the GM-CSF receptor. Journal of Leukocyte Biology, 72(6), 1246-1255.
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2001 Gonda, T., & Ramsay, R. (2001). The Second International Workshop on Myb Genes: Foreword. Blood Cells Molecules and Diseases, 27(2), 407-408.
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2001 Lutwyche, J., Keough, R., Hughes, T., & Gonda, T. (2001). Mutation screening of the c-MYB negative regulatory domain in acute and chronic myeloid leukaemia. British Journal of Haematology, 114(3), 632-634.
DOI Scopus9 WoS9 Europe PMC9
2001 Bartley, P., Lutwyche, J., & Gonda, T. (2001). Identification and validation of candidate Myb target genes. Blood Cells Molecules and Diseases, 27(2), 409-415.
DOI Scopus7 WoS6 Europe PMC6
2000 Le, F., Stomski, F., Woodcock, J., Lopez, A., & Gonda, T. (2000). The role of disulfide-linked dimerization in interleukin-3 receptor signaling and biological activity. Journal of Biological Chemistry, 275(7), 5124-5130.
DOI Scopus21 WoS19 Europe PMC17
2000 D'Andrea, R., & Gonda, T. (2000). A model for assembly and activation of the GM-CSF, IL-3 and IL-5 receptors: insights from activated mutants of the common b subunit. Experimental Hematology, 28(3), 231-243.
DOI Scopus53 WoS46 Europe PMC39
2000 McCormack, M., & Gonda, T. (2000). Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor b subunit. Blood, 95(1), 120-127.
DOI Scopus19 WoS19 Europe PMC14
1999 McCormack, M., & Gonda, T. (1999). Myeloproliferative disorder and leukaemia in mice induced by different classes of constitutive mutants of the human IL-3/IL-5/GM-CSF receptor common B subunit. Oncogene, 18(-), 7190-7199.
1999 Jenkins, B., Le, F., & Gonda, T. (1999). A cell type-specific constitutive point mutant of the common β-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor α-subunit for activation. Journal of Biological Chemistry, 274(13), 8669-8677.
DOI Scopus17 WoS17 Europe PMC12
1999 Keough, R., Woollatt, E., Crawford, J., Sutherland, G., Plummer, S., Casey, G., & Gonda, T. (1999). Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3. Genomics, 62(3), 483-489.
DOI Scopus17 WoS18 Europe PMC15
1999 McCormack, M. P., & Gonda, T. J. (1999). Myeloproliferative disorder and leukaemia in mice induced by different classes of constitutive mutants of the human IL-3/IL-5/GM-CSF receptor common β subunit. Oncogene, 18(51), 7190-7199.
DOI Scopus14 WoS17 Europe PMC16
1998 Jenkins, B. J., Blake, T. J., & Gonda, T. J. (1998). Saturation mutagenesis of the β subunit of the human granulocyte-macrophage colony-stimulating factor receptor shows clustering of constitutive mutations, activation of ERK MAP kinase and STAT pathways, and differential β subunit tyrosine phosphorylation. BLOOD, 92(6), 1989-2002.
DOI WoS34 Europe PMC21
1998 Jenkins, B., Blake, T., & Gonda, T. (1998). Saturation mutagenesis of the β subunit of the human GM-CSF receptor shows clustering of constitutive mutations, activation of ERK MAP kinase and STAT pathways, and differential β subunit tyrosine phosphorylation. Blood, 92(6), 1989-2002.
DOI Scopus36
1998 Gonda, T. (1998). The c-Myb oncoprotein. International Journal of Biochemistry and Cell Biology, 30(5), 547-551.
DOI Scopus41 WoS38 Europe PMC36
1998 D'Andrea, R., Harrison-Findik, D., Butcher, C., Finnie, J., Blumbergs, P., Bartley, P., . . . Vadas, M. (1998). Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common β chain in transgenic mice. Journal of Clinical Investigation, 102(11), 1951-1960.
DOI Scopus29 WoS30 Europe PMC24
1998 Tavner, F., Simpson, R., Tashiro, S., Favier, D., Jenkins, N., Gilbert, D., . . . Gonda, T. (1998). Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly necleolar protein which may play a role in transactivation by Myb. Molecular and Cellular Biology, 18(2), 989-1002.
DOI Scopus76 WoS76 Europe PMC70
1998 Caruana, G., Cambarer, A., Gonda, T., & Ashman, L. (1998). Transformation of NIH3T3 fibroblasts by the c-kit receptor tyrosine kinase; effect of receptor density and ligand-requirement. Oncogene, 16(2), 179-190.
DOI Scopus24 WoS24 Europe PMC19
1998 Bartley, P., & Gonda, T. (1998). The Tenth Annual Lorne Cancer Conference. Cancer Forum, 22(2), 156-158.
1997 Starr, R., Willson, T., Viney, E., Murray, L., Rayner, J., Jenkins, B., . . . Hilton, D. (1997). A family of cytokine-inducible inhibitors of signalling.. Nature, 387(6636), 917-921.
DOI Scopus1884 WoS1808 Europe PMC1523
1997 Hogg, A., Schirm, S., Nakagoshi, H., Bartley, P., Ishii, S., Bishop, J., & Gonda, T. (1997). Inactivation of a c-Myb/estrogen receptor fusion protein in transformed primary cells leads to granulocyte/macrophage differentiation and down regulation of c-kit but not c-myc or cdc2.. Oncogene, 15(24), 2885-2898.
DOI Scopus53 WoS56 Europe PMC47
1997 Ferrao, P., Gonda, T., & Ashman, L. (1997). Expression of constitutively activated human c'Kit in Myb transformed early myeloid cells leads to factor independence.. Blood, 90, 4539-4552.
1997 McCormack, M., & Gonda, T. (1997). Expression of activated mutants of the human interleukin-3/interleukin-5/granulocyte-macrophage colony-stimulating factor receptor common beta subunit in primary hematopoietic cells induces factor-independent proliferation and differentiation.. Blood, 90(4), 1471-1481.
DOI Scopus27 WoS30 Europe PMC18
1997 Gonda, T., & D'Andrea, R. (1997). Activating mutations in cytokine receptors: implications for receptor function and role in disease.. Blood, 89(2), 355-369.
DOI Scopus45 WoS47 Europe PMC24
1997 Ferrao, P., Gonda, T. J., & Ashman, L. K. (1997). Expression of constitutively activated human c-Kit in Myb transformed early myeloid cells leads to factor independence, histiocytic differentiation, and tumorigenicity. Blood, 90(11), 4539-4552.
DOI Scopus36 WoS39 Europe PMC21
1996 Gonda, T. J., Favier, D., Ferrao, P., Macmillan, E. M., Simpson, R., & Tavner, F. (1996). The c-myb negative regulatory domain. Current Topics in Microbiology and Immunology, 211, 99-109.
DOI Scopus12 WoS12 Europe PMC9
1996 Zannettino, A., Rayner, J., Ashman, L., Gonda, T., & Simmons, P. (1996). A powerful new technique for isolating genes encoding cell surface antigens using retroviral expression cloning. Journal of Immunology, 156(2), 611-620.
DOI Scopus41 WoS41 Europe PMC25
1996 Jenkins, B., Bagley, C., Woodcock, J., Lopez, A., & Gonda, T. (1996). Interacting residues ion the extracellular region of the common β subunit of the human granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptors involved in constitutive activation. Journal of Biological Chemistry, 271(47), 29707-29714.
DOI Scopus22 WoS22 Europe PMC20
1995 Jenkins, B., D'Andrea, R., & Gonda, T. (1995). Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling. EMBO Journal, 14(17), 4276-4287.
DOI Scopus76 WoS78 Europe PMC46
1995 Ferrao, P., Macmillan, E., Ashman, L., & Gonda, T. (1995). Enforced expression of full length c-Myb leads to density dependent transformation of murine haemopoietic cells. Oncogene, 11(8), 1631-1638.
Scopus42 WoS43 Europe PMC32
1994 D'Andrea, R., Rayner, J., Moretti, P., Lopez, A., Goodall, G. J., Gonda, T. J., & Vadas, M. (1994). A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. Blood, 83(10), 2802-2808.
DOI Scopus54 WoS57 Europe PMC27
1994 Rayner, J. R., & Gonda, T. J. (1994). A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector. Molecular and Cellular Biology, 14(2), 880-887.
DOI Scopus76 WoS75 Europe PMC40
1994 Favier, D., & Gonda, T. J. (1994). Detection of proteins that bind to the leucine zipper motif of c-Myb. Oncogene, 9(1), 305-311.
Scopus43 WoS56 Europe PMC43
1994 Macmillan, E. M., & Gonda, T. J. (1994). Murine Myeloid Cells Transformed by myb Require Fibroblast-Derived or Autocrine Growth Factors in Addition to Granulocyte-Macrophage Colony-Stimulating Factor for Proliferation. Blood, 83(1), 209-216.
DOI Scopus9 WoS10 Europe PMC2
1994 Favier, D., & Gonda, T. J. (1994). Detection of proteins that bind to the leucine zipper motif of c-Myb. Oncogene, 9(1), XXIII-XXIV.
Scopus7
1993 Gonda, T. J., Macmillan, E. M., Townsend, P. V., & Hapel, A. J. (1993). Differentiation state and responses to hematopoietic growth factors of murine myeloid cells transformed by myb. Blood, 82(9), 2813-2822.
DOI Scopus23 WoS26 Europe PMC15
1993 Caruana, G., Ashman, L. K., Fujita, J., & Gonda, T. J. (1993). Responses of the murine myeloid cell line FDC-P1 to soluble and membrane-bound forms of steel factor (SLF). Experimental Hematology, 21(6), 761-768.
Scopus35 WoS37 Europe PMC15
1993 ZANNETTINO, A. C. W., RAYNER, J. R., ASHMAN, L. K., GONDA, T. J., & SIMMONS, P. J. (1993). USE OF A RETROVIRAL CDNA EXPRESSION LIBRARY TO CLONE GENES ENCODING NOVEL HUMAN STROMAL CELL ANTIGENS. JOURNAL OF LEUKOCYTE BIOLOGY, 103.
1993 Nomura, T., Sakai, N., Sarai, A., Sudo, T., Kanei-Ishii, C., Ramsay, R. G., . . . Ishii, S. (1993). Negative autoregulation of c-myb activity by homodimer formation through the leucine zipper. Journal of Biological Chemistry, 268(29), 21914-21923.
DOI Scopus71 WoS76 Europe PMC51
1992 Kanei-Ishii, C., Macmillan, E. M., Nomura, T., Sarai, A., Ramsay, R. G., Aimoto, S., . . . Gonda, T. J. (1992). Transactivation and transformation by Myb are negatively regulated by a leucine-zipper structure. Proceedings of the National Academy of Sciences of the United States of America, 89(7), 3088-3092.
DOI Scopus113 WoS122 Europe PMC85
1992 Ramsay, R. G., Thompson, M. A., Hayman, J. A., Reid, G., Gonda, T. J., & Whitehead, R. H. (1992). Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa.. Cell Growth Differentiation the Molecular Biology Journal of the American Association for Cancer Research, 3(10), 723-730.
Scopus85 WoS84 Europe PMC60
1992 Ramsay, R. G., Ishii, S., & Gonda, T. J. (1992). Interaction of the Myb protein with specific DNA binding sites. Journal of Biological Chemistry, 267(8), 5656-5662.
DOI Scopus37 WoS40 Europe PMC27
1991 Ramsay, R. G., Ishii, S., & Gonda, T. J. (1991). Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb. Oncogene, 6(10), 1875-1879.
Scopus55 WoS57 Europe PMC36
1991 Hu, Y., Ramsay, R. G., Kanei-Ishii, C., Ishii, S., & Gonda, T. J. (1991). Transformation by carboxyl-deleted Myb reflects increased transactivating capacity and disruption of a negative regulatory domain. Oncogene, 6(9), 1549-1553.
Scopus108 WoS115 Europe PMC70
1991 Gonda, T. J. (1991). Targets for trans-activation by myb. Cancer Cells, 3(1), 22-23.
Scopus1 WoS3 Europe PMC1
1990 Vairo, G., Argyriou, S., Bordun, A. M., Gonda, T. J., Cragoe, E. J., & Hamilton, J. A. (1990). Na+/H+ exchange involvement in colony-stimulating factor-1-stimulated macrophage proliferation: Evidence for a requirement during late G1 of the cell cycle but not for early growth factor responses. Journal of Biological Chemistry, 265(28), 16929-16939.
DOI Scopus45 WoS43 Europe PMC30
1989 Ramsay, R. G., Ishi, S., Nishina, Y., Soe, G., & Gonda, T. J. (1989). Characterization of alternate and truncated forms of murine c-myb proteins. Oncogene Research, 4(4), 259-269.
Scopus68 WoS71 Europe PMC52
1989 Sobieszczuk, P. W., Gonda, T. J., & Dunn, A. R. (1989). Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene. Nucleic Acids Research, 17(23), 9593-9611.
DOI Scopus14 WoS14 Europe PMC12
1989 Nishina, Y., Nakagoshi, H., Imamoto, F., Gonda, T. J., & Ishii, S. (1989). Trans-activation by the c-myb proto-oncogene. Nucleic Acids Research, 17(1), 107-117.
DOI Scopus131 WoS150 Europe PMC89
1989 Chang, J. M., Metcalf, D., Lang, R. A., Gonda, T. J., & Johnson, G. R. (1989). Nonneoplastic hematopoietic myeloproliferative syndrome induced by dysregulated Multi-CSF (IL-3) expression. Blood, 73(6), 1487-1497.
DOI Scopus114 WoS135 Europe PMC64
1989 Hamilton, J. A., Veis, N., Bordun, A., Vairo, G., Gonda, T. J., & Phillips, W. A. (1989). Activation and proliferation signals in murine macrophages: Relationships among c‐fos and c‐myc expression, phosphoinositide hydrolysis, superoxide formation, and DNA synthesis. Journal of Cellular Physiology, 141(3), 618-626.
DOI Scopus39 WoS40 Europe PMC26
1989 Hariharan, I. K., Johnson, G. R., Gonda, T. J., Metcalf, D., Adams, J. M., & Cory, S. (1989). Analysis of the leukemogenic properties of the bcr-v-abl and GM-CSF genes using a new retroviral vector.. Current Topics in Microbiology and Immunology, 149, 99-107.
DOI Scopus2 WoS2
1989 Johnson, G. R., Gonda, T. J., Metcalf, D., Kariharan, I. K., & Cory, S. (1989). A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor. EMBO Journal, 8(2), 441-448.
DOI Scopus180 WoS201 Europe PMC116
1989 Gonda, T. J., Ramsay, R. G., & Johnson, G. R. (1989). Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses. EMBO Journal, 8(6), 1767-1775.
DOI Scopus54 WoS56 Europe PMC31
1989 Gonda, T. J., Buckmaster, C., & Ramsay, R. G. (1989). Activation of c-myb by carboxy-terminal truncation: Relationship to transfomration of murine haemopoietic cells in vitro. EMBO Journal, 8(6), 1777-1783.
DOI Scopus100 WoS105 Europe PMC70
1989 Sakura, H., Kanei-Ishii, C., Nagase, T., Nakagoshi, H., Gonda, T. J., & Ishii, S. (1989). Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene. Proceedings of the National Academy of Sciences of the United States of America, 86(15), 5758-5762.
DOI Scopus354 WoS374 Europe PMC234
1989 Chang, J. M., Metcalf, D., Gonda, T. J., & Johnson, G. R. (1989). Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice. Journal of Clinical Investigation, 84(5), 1488-1496.
DOI Scopus75 WoS82 Europe PMC47
1988 Bowtell, D. D. L., Cory, S., Johnson, G. R., & Gonda, T. J. (1988). Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes. Journal of Virology, 62(7), 2464-2473.
DOI Scopus96 WoS109 Europe PMC73
1987 Gonda, T. J., Cory, S., Sobieszczuk, P., Holtzman, D., & Adams, J. M. (1987). Generation of altered transcripts by retroviral insertion within the c-myb gene in two murine monocytic leukemias. Journal of Virology, 61(9), 2754-2763.
DOI Scopus44 WoS58 Europe PMC36
1987 Lang, R. A., Metcalf, D., Cuthbertson, R. A., Lyons, I., Stanley, E., Kelso, A., . . . Dunn, A. R. (1987). Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage. Cell, 51(4), 675-686.
DOI Scopus325 WoS370 Europe PMC257
1986 Gonda, T., & Dunn, A. (1986). A molecular basis for growth regulation in normal and neoplastic hemopoiesis. Cancer Reviews, Vol. 3, 58-90.
1985 Lang, R. A., Metcalf, D., Gough, N. M., Dunn, A. R., & Gonda, T. J. (1985). Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity. Cell, 43(2 PART 1), 531-542.
DOI Scopus200 WoS295 Europe PMC168
1985 Gonda, T. J., Gough, N. M., Dunn, A. R., & de Blaquiere, J. (1985). Nucleotide sequence of cDNA clones of the murine myb proto-oncogene.. EMBO Journal, 4(8), 2003-2008.
DOI Scopus150 WoS194 Europe PMC146
1984 Gonda, T. J., & Metcalf, D. (1984). Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia. Nature, 310(5974), 249-251.
DOI Scopus457 WoS630 Europe PMC409
1983 Gonda, T. J., & Bishop, J. M. (1983). Structure and transcription of the cellular homolog (c-myb) of the avian myeloblastosis virus transforming gene (v-myb). Journal of Virology, 46(1), 212-220.
DOI Scopus55 WoS83 Europe PMC53
1982 Gonda, T. J., Sheiness, D. K., & Bishop, J. M. (1982). Transcripts from the cellular homologs of retroviral oncogenes: Distribution among chicken tissues. Molecular and Cellular Biology, 2(6), 617-624.
DOI Scopus318 WoS485 Europe PMC283
1982 Klempnauer, K. H., Gonda, T. J., & Michael Bishop, J. (1982). Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene. Cell, 31(2 PART 1), 453-463.
DOI Scopus416 WoS523 Europe PMC399
1981 Gonda, T. J., Sheiness, D. K., Fanshier, L., Michael Bishop, J., Moscovici, C., & Giovannella Moscovici, M. (1981). The genome and the intracellular RNAs of avian myeloblastosis virus. Cell, 23(1), 279-290.
DOI Scopus26 WoS79 Europe PMC59
1980 Sheiness, D., Bister, K., Moscovici, C., Fanshier, L., Gonda, T., & Bishop, J. M. (1980). Avian retroviruses that cause carcinoma and leukemia: Identification of nucleotide sequences associated with pathogenicity. Journal of Virology, 33(3), 962-968.
DOI Scopus22 Europe PMC31
1979 Gonda, T. J., & Symons, R. H. (1979). Cucumber mosaic virus replication in cowpea protoplasts: Time course of virus, coat protein and RNA synthesis. Journal of General Virology, 45(3), 723-736.
DOI Scopus26 WoS31
1978 Gonda, T. J., & Symons, R. H. (1978). The use of hybridization analysis with complementary DNA to determine the RNA sequence homology between strains of plant viruses: Its application to several strains of cucumoviruses. Virology, 88(2), 361-370.
DOI Scopus50 WoS77 Europe PMC34
1974 Scholz, M., Karpati, G., Varadi, I., & Gonda, T. (1974). Histomorphological and histochemical study of uterine cancer after preoperative irradiation (Hungarian). Magyar Onkologia, 18(3), 179-185.

Year Citation
2016 Bassal, M. A., Leo, P., Samaraweera, S. E., Maung, K. Z. Y., Babic, M., Venugopal, P., . . . D'Andrea, R. (2016). Metabolic Profiling of Adult Acute Myeloid Leukemia (AML). In BLOOD Vol. 128 (pp. 6 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI WoS1
2016 Maung, K. Z. Y., Leo, P., Brown, A. L., Bassal, M. A., Casolari, D. A., Ewing, A., . . . D'Andrea, R. (2016). Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML. In BLOOD Vol. 128 (pp. 5 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI
2016 Yang, R. -M., Dray, E., Mitra, P., & Gonda, T. J. (2016). MYB is involved in the DNA damage response in human ER<SUP>+</SUP> breast cancer cells. In CANCER RESEARCH Vol. 76 (pp. 2 pages). TX, San Antonio: AMER ASSOC CANCER RESEARCH.
DOI
2015 Gabrielli, B. G., Bokhari, F., Ranall, M., Oo, Z. Y., Stevenson, A., Wang, W., . . . McMillan, N. A. J. (2015). Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer. In CANCER RESEARCH Vol. 75 (pp. 3 pages). PA, Philadelphia: AMER ASSOC CANCER RESEARCH.
DOI
2015 Hahn, C. N., Babic, M., Schreiber, A. W., Kutyna, M. M., Wee, L. A., Brown, A. L., . . . Hiwase, D. (2015). Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome. In BLOOD Vol. 126 (pp. 4 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS3
2014 Brown, A. L., Sadras, T., Engler, G. A., Tunningley, R., Kofler, J., Leo, P. J., . . . D'Andrea, R. J. (2014). An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm. In BLOOD Vol. 124 (pp. 3 pages). San Francisco, CA: AMER SOC HEMATOLOGY.
2013 Gonda, T. J. (2013). THE <i>MYB</i> ONCOGENE AS A THERAPEUTIC TARGET IN MULTIPLE CANCER TYPES: WHY AND HOW?. In CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY Vol. 40 (pp. 15-16). PEOPLES R CHINA, Hangzhou: WILEY-BLACKWELL.
2010 Brown, A. L., Salerno, D. G., Wilkinson, C., Sadras, T., Kok, C., Perugini, M., . . . D'Andrea, R. J. (2010). THE GM-CSF RECEPTOR UTILIZES BETA-CATENIN AND TCF4 TO SPECIFY MACROPHAGE LINEAGE DIFFERENTIATION. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S46). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2009 Hammond, E., Bytheway, I., Handley, P., Kappler, M., McGirr, C., Gonda, T. J., . . . Dredge, K. (2009). The dual angiogenesis/heparanase inhibitor PG545 inhibits solid tumor progression in models of breast, prostate and liver cancer: A comparative assessment of once versus twice weekly administration schedules. In MOLECULAR CANCER THERAPEUTICS Vol. 8 (pp. 2 pages). AMER ASSOC CANCER RESEARCH.
DOI
2008 Zhao, L., Al-Owaidi, F., Pattabiraman, D. R., Verrier, E., Tsykin, A., Goodall, G. J., . . . Gonda, T. J. (2008). Identification of Novel MYB Target Genes. In BLOOD Vol. 112 (pp. 1224-1225). San Francisco, CA: AMER SOC HEMATOLOGY.
2007 Perugini, M., Kok, C. H., Wilkinson, C. R., Salerno, D. G., Brown, A. L., Gonda, T. J., & D'Andrea, R. J. (2007). Down-regulation of GADD45A by FLT3 and GMCSF receptor activated mutants results in suppression of myeloid differentiation and enhanced proliferative potential. In EXPERIMENTAL HEMATOLOGY Vol. 35 (pp. 101). Hamburg, GERMANY: ELSEVIER SCIENCE INC.
2007 Diakiw, S. M., Brown, A. L., Salerno, D. G., Gonda, T. J., Murphy, K., Bardy, P. G., . . . D'Andrea, R. J. (2007). Identification of oncogenes from myeloid leukemias by retroviral expression cloning. In EXPERIMENTAL HEMATOLOGY Vol. 35 (pp. 72). Hamburg, GERMANY: ELSEVIER SCIENCE INC.
2005 Perugini, M., Brown, A., Gonda, T. J., & D'Andrea, R. J. (2005). Signal transduction changes induced by constitutive mutants of the granulocyte macrophage colony-stimulating factor receptor: Understanding the leukemogenic potential of mutants of the common beta subunit. In EXPERIMENTAL HEMATOLOGY Vol. 33 (pp. 87). Univ Glasgow, Glasgow, SCOTLAND: ELSEVIER SCIENCE INC.
2005 Brown, A. L., Wilkinson, C., Waterman, S., Salerno, D., Diakiw, S., Tsykin, A., . . . D'Andrea, R. J. (2005). Analysis of gene expression changes induced by leukaemogenic mutants of the GM-CSF receptor reveals genes important for self-renewal versus differentiation of myeloid cells. In EXPERIMENTAL HEMATOLOGY Vol. 33 (pp. 65). Univ Glasgow, Glasgow, SCOTLAND: ELSEVIER SCIENCE INC.
2005 Wilkinson, C., Brown, A., Kok, C., Solomon, P., Goodall, G., Gonda, T., & D'Andrea, M. (2005). Expression profiling of a myeloid cell line model to identify novel transcription factors influencing myeloid cell differentiation proliferation and leukaemia. In Proceedings of 5th Australian Microarray Conference 2005 (pp. unknown). Australia: Unknown.
2001 Phan, V. T., Gonda, T. J., & Hogan, S. C. (2001). PML-RARα cooperates with activated cytokine receptors to cause acute leukemia. In BLOOD Vol. 98 (pp. 456A). AMER SOC HEMATOLOGY.
1999 Gonda, T. J., McCormack, M. P., Blake, T. J., & D'Andrea, R. J. (1999). Effects of constitutive mutants of the GM-CSF/IL-3/IL-5 receptor β subunit on proliferation and differentiation of haemopoietic cells <i>in vitro</i> and <i>in vivo</i>.. In BLOOD Vol. 94 (pp. 148B). AMER SOC HEMATOLOGY.
1998 McCormack, M. P., Jenkins, B. J., & Gonda, T. J. (1998). Activated mutants of the human gm-csf receptor β subunit cause myeloproliferative disorders and leukaemia in mice. In Experimental Hematology Vol. 26 (pp. 754). CARDEN JENNINGS PUBL CO LTD.
1998 McCormack, M. P., & Gonda, T. J. (1998). Activated mutants of the human GM-CSF receptor β subunit cause myeloproliferative disorders and leukaemia in mice.. In BRITISH JOURNAL OF CANCER Vol. 78 (pp. 22). CHURCHILL LIVINGSTONE.
1993 FAVIER, D., NOMURA, T., ISHII, S., & GONDA, T. J. (1993). IDENTIFICATION OF PROTEINS WHICH INTERACT WITH THE C-MYB LEUCINE-ZIPPER - IMPLICATIONS FOR THE REGULATION OF MYB ACTIVITY. In JOURNAL OF LEUKOCYTE BIOLOGY (pp. 133). FEDERATION AMER SOC EXP BIOL.
1989 HARIHARAN, I. K., JOHNSON, G. R., GONDA, T. J., METCALF, D., ADAMS, J. M., & CORY, S. (1989). ANALYSIS OF THE LEUKEMOGENIC PROPERTIES OF THE BCR-V-ABL AND GM-CSF GENES USING A NEW RETROVIRAL VECTOR. In G. L. C. SHENONG, M. POTTER, & N. G. COPELAND (Eds.), MECHANISMS IN MYELOID TUMORIGENESIS 1988 Vol. 149 (pp. 99-107). MD, NCI, BETHESDA: SPRINGER-VERLAG BERLIN.
1987 HAMILTON, J. A., RILEY, C. G., VAIRO, G., & GONDA, T. J. (1987). ONCOGENE EXPRESSION IN PROLIFERATING AND NONPROLIFERATING MACROPHAGES. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE Vol. 17 (pp. 167). ADIS PRESS AUSTRALASIA P/L.
1986 DUNN, A. R., GOUGH, N. M., STANLEY, E., GONDA, T. J., LANG, R., & METCALF, D. (1986). HEMATOPOIETIC GROWTH-FACTOR GENE-SEQUENCES AND THEIR ROLE IN GROWTH-CONTROL. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE Vol. 16 (pp. 126). ADIS PRESS AUSTRALASIA P/L.
1986 GONDA, T. J., DEBLAQUIERE, J., & JOHNSON, G. (1986). REQUIREMENTS FOR TRANSFORMATION BY THE MYB ONCOGENE. In JOURNAL OF CELLULAR BIOCHEMISTRY (pp. 151). WILEY-LISS.
1984 GONDA, T. J. (1984). CELLULAR ONCOGENES IN HEMATOPOIESIS. In PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY Vol. 16 (pp. S21). PROC AUST BIOCHEMICAL SOC.
1979 GOULD, A. R., & GONDA, T. J. (1979). 2 DIMENSIONAL ELECTROPHORETIC ANALYSIS OF CUCUMBER MOSAIC-VIRUS INDUCED PROTEINS UPON INFECTION OF COWPEA PROTOPLASTS. In PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY Vol. 12 (pp. 73). PROC AUST BIOCHEMICAL SOC.

Year Citation
2014 Maung, K. Z., Gray, J. X., Leo, P. J., Bassal, M., Brown, A. L., Bray, S. C., . . . Gonda, T. J. (2014). Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes. Poster session presented at the meeting of BLOOD. San Francisco, CA: AMER SOC HEMATOLOGY.

Year Citation
2011 Gonda, T. J., & Kremmidiotis, G. (2011). US20110064730, Method of modulating angiogenesis.

  • The role of the GADD45A gene in AML pathogenesis and response to therapy, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017

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