Timothy Kleinig

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Timothy Kleinig - Clinical Professor.
My research interests include acute stroke reperfusion treatments, acute intracerebral haemorrhage treatment, multimodal stroke imaging, secondary prevention, stroke epidemiology and rare stroke variants. I also collaborate with other teams on stroke in Aboriginal patients and also Biomedical engineers on a novel post-stroke bioprosthesis.

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Professional Activities
Contact

My research interests include acute stroke reperfusion treatments, multimodal stroke imaging, secondary prevention, stroke epidemiology and rare stroke variants, including embolic stroke of undetermined source in the young. I also collaborate with other teams on stroke in Aboriginal patients and also Biomedical engineers on a novel post-stroke bioprosthesis.

Appointments

Date	Position	Institution name
2020 - ongoing	Clinical Professor	University of Adelaide
2013 - 2020	Clinical Associate Professor	University of Adelaide
2012 - ongoing	Head of Department of Neurology and Stroke	Lyell McEwin Hospital
2012 - ongoing	Head of Stroke Unit	Royal Adelaide Hospital
2010 - ongoing	Clinical Senior Lecturer	University of Adelaide
2007 - 2010	Duty Medical Officer	Memorial Private Hospital
2007 - ongoing	Consultant Neurologist	Royal Adelaide Hospital
2006 - 2007	Elective year as stroke fellow	Royal Adelaide Hospital
2004 - 2006	Neurology Registrar Core training	Royal Adelaide Hospital
2004 - ongoing	Chief Medical Resident	Royal Adelaide Hospital
2003 - 2010	Clinical Associate Lecturer	University of Adelaide
2001 - 2003	Basic Physician trainee	Royal Adelaide Hospital
2000 - ongoing	Resident Medical Officer	Flinders Medical Centre
1999 - ongoing	Intern	Flinders Medical Centre
1996 - 1998	Senior Academic Tutor	St Peter's College, Boarding House
1995 - ongoing	President	Adelaide University Union

Awards and Achievements

Date	Type	Title	Institution Name	Country
2013	Award	LMH award for best Medical grand round of the Year
2012	Award	Preofessor Derek Frewin citation for Excellence in Clinical teaching
2010	Award	Elizabeth Simpson Memorial Prize		Australia
2008	Recognition	Best Oral Presentation by a PhD candidate	University of Adelaide, Faculty of Health Sciences Research Expo	Australia
2007	Scholarship	Joint NHMRC/NHF PhD scholarship
2007	Scholarship	Dawes' PhD scholarship	Royal Adelaide Hospital	Australia
2007	Award	Professor John Chalmers Prize for the best research by an advanced physician trainee in South Australia		Australia
2007	Recognition	National		Australia
2006	Recognition	New Investigator Award	Stroke Society of Australasia annual meeting	Australia
2006	Recognition	Young Investigator Award	Australian and New Zealand Association of Neurologists	Australia
2003	Recognition	Nominee 'Best clinical teacher' by 6th Year Medical Students		Australia
2001	Recognition	Finalist Nimmo prize	Royal Adelaide Hospital	Australia
1995	Recognition	Dux of Ancient Greek 1
1993	Scholarship	D.A.A.D. Scholarship for language course in Freiburg, Germany		Germany

Education

Date	Institution name	Country	Title
2007 - 2010	University of Adelaide	Australia	Docor of Philosophy
2001 - 2007	Royal Australasian College of Physicians (Neurology)	Australia	Fellow
1995 - 1998	University of Adelaide	Australia	M.B.B.S. (Hons)
1995	Elder Conservatorium	Australia	Single Studies in Composition
1991 - 1995	University of Adelaide	Australia	Bachelor of Arts (double German major)
1991 - 1993	University of Adelaide	Australia	M.B.B.S (Hons)

Journals

Year	Citation
2022	Bacchi, S., Tan, Y., Oakden-Rayner, L., Jannes, J., Kleinig, T., & Koblar, S. (2022). Machine Learning in the Prediction of Medical Inpatient Length of Stay.. Intern Med J, 52(2), 176-185. DOI Scopus5 WoS1 Europe PMC2
2022	Kelly, J., Dowling, A., Hillier, S., Brown, A., Kleinig, T., Goldsmith, K., . . . Thrift, A. G. (2022). Perspectives on rehabilitation for Aboriginal people with stroke: a qualitative study. Topics in Stroke Rehabilitation, 29(4), 295-309. DOI
2022	Hostettler, I. C., Wilson, D., Fiebelkorn, C. A., Aum, D., Ameriso, S. F., Eberbach, F., . . . Werring, D. J. (2022). Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis. Journal of Neurology, 269(3), 1427-1438. DOI
2022	Bacchi, S., Gilbert, T., Gluck, S., Cheng, J., Tan, Y., Chim, I., . . . Koblar, S. (2022). Daily estimates of individual discharge likelihood with deep learning natural language processing in general medicine: a prospective and external validation study. Internal and Emergency Medicine, 17(2), 411-415. DOI
2022	Yogendrakumar, V., Churilov, L., Mitchell, P. J., Kleinig, T. J., Yassi, N., Thijs, V., . . . Sharma, G. (2022). Safety and Efficacy of Tenecteplase in Older Patients with Large Vessel Occlusion: A Pooled Analysis of the EXTEND-IA TNK Trials. Neurology, 98(12), E1292-E1301. DOI Scopus2 WoS1
2022	Milton, A. G., Lau, S., Kremer, K. L., Rao, S. R., Mas, E., Snel, M. F., . . . Koblar, S. A. (2022). FAST-IT: F ind A S imple T est- I n T IA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass spectrometry, neuroimaging and machine learning - study protocol. BMJ Open, 12(4), 9 pages. DOI
2022	Cadilhac, D. A., Kim, J., Cloud, G., Anderson, C. S., Tod, E. K., Breen, S. J., . . . AuSCR COVID-19 Reporting Consortium Group. (2022). Effect of the coronavirus disease 2019 pandemic on the quality of stroke care in stroke units and alternative wards: a national comparative analysis. Journal of Stroke, 24(1), 79-87. DOI
2022	Ng, F. C., Churilov, L., Yassi, N., Kleinig, T. J., Thijs, V., Wu, T. Y., . . . EXTEND-IA TNK Part 1 and 2 Investigators. (2022). Reduced Severity of Tissue Injury Within the Infarct May Partially Mediate the Benefit of Reperfusion in Ischemic Stroke. Stroke, 53(6), 1915-1923. DOI Scopus1 WoS1
2022	Bacchi, S., Gluck, S., Koblar, S., Jannes, J., & Kleinig, T. (2022). Automated information extraction from free-text medical documents for stroke key performance indicators: a pilot study. Internal Medicine Journal, 52(2), 315-317. DOI
2022	Yogendrakumar, V., Wu, T. Y., Churilov, L., Tatlisumak, T., Strbian, D., Jeng, J. S., . . . Yassi, N. (2022). Does tranexamic acid affect intraventricular hemorrhage growth in acute ICH? An analysis of the STOP-AUST trial. European Stroke Journal, 7(1), 15-19. DOI WoS1
2022	Ovenden, C. D., Hiwase, A., Gyi, A. A., Abou-Hamden, A., & Kleinig, T. (2022). The Predictive Accuracy of the Delayed Spot Sign for Haematoma Expansion in Spontaneous Supratentorial Intracerebral Haemorrhage: A Systematic Review and Meta-Analysis. Journal of Stroke and Cerebrovascular Diseases, 31(5), 9 pages. DOI Scopus1 WoS1
2022	Ryan, A., Paul, C. L., Cox, M., Whalen, O., Bivard, A., Attia, J., . . . Levi, C. R. (2022). TACTICS - Trial of Advanced CT Imaging and Combined Education Support for Drip and Ship: evaluating the effectiveness of an 'implementation intervention' in providing better patient access to reperfusion therapies: protocol for a non-randomised controlled stepped wedge cluster trial in acute stroke. BMJ open, 12(2), e055461. DOI
2022	Sarraj, A., Parsons, M., Bivard, A., Hassan, A. E., Abraham, M. G., Wu, T., . . . SELECT Investigators, the EXTEND-IA Investigators, the EXTEND-IA TNK Investigators, the EXTEND-IA TNK Part II Investigators, and the INSPIRE Study Group. (2022). Endovascular Thrombectomy versus Medical Management in Isolated M2 Occlusions: Pooled Patient-Level Analysis from the EXTEND-IA Trials, INSPIRE and SELECT Studies. Annals of Neurology, 91(5), 629-639. DOI Scopus1 WoS1
2022	Alemseged, F., Rocco, A., Arba, F., Schwabova, J. P., Wu, T., Cavicchia, L., . . . Campbell, B. C. V. (2022). Posterior National Institutes of Health Stroke Scale Improves Prognostic Accuracy in Posterior Circulation Stroke. Stroke, 53(4), 1247-1255. DOI Scopus2
2022	Garcia-Esperon, C., Bladin, C. F., Kleinig, T. J., Brown, H., Majersik, J. J., Wesseldine, A., & Butcher, K. (2022). The acute telestroke model of care in Australia: a potential roadmap for other emergency medical services?. Medical Journal of Australia, 216(10), 498-500. DOI
2022	Truong, M. Q., Metcalfe, A. V., Ovenden, C. D., Kleinig, T. J., & Barras, C. D. (2022). Intracerebral hemorrhage markers on non-contrast computed tomography as predictors of the dynamic spot sign on CT perfusion and associations with hematoma expansion and outcome. Neuroradiology, 10 pages. DOI
2022	Ovenden, C. D., Hewitt, J., Kovoor, J., Gupta, A., Edwards, S., Abou-Hamden, A., & Kleinig, T. (2022). Time to hospital presentation following intracerebral haemorrhage: Proportion of patients presenting within eight hours and factors associated with delayed presentation.. J Stroke Cerebrovasc Dis, 31(11), 106758. DOI
2022	van de Munckhof, A., Lindgren, E., Kleinig, T. J., Field, T. S., Cordonnier, C., Krzywicka, K., . . . Coutinho, J. M. (2022). Outcomes of Cerebral Venous Thrombosis due to Vaccine-Induced Immune Thrombotic Thrombocytopenia After the Acute Phase.. Stroke, 101161STROKEAHA122039575. DOI
2022	Truong, M. Q., Metcalfe, A. V., Ovenden, C. D., Kleinig, T. J., & Barras, C. D. (2022). Correction to: Intracerebral hemorrhage markers on non‑contrast computed tomography as predictors of the dynamic spot sign on CT perfusion and associations with hematoma expansion and outcome.. Neuroradiology. DOI
2022	Zeng, M., Oakden-Rayner, L., Bird, A., Smith, L., Wu, Z., Scroop, R., . . . Palmer, L. J. (2022). Pre-thrombectomy prognostic prediction of large-vessel ischemic stroke using machine learning: A systematic review and meta-analysis.. Front Neurol, 13, 945813. DOI
2022	Lindgren, E., Rentzos, A., Hiltunen, S., Serrano, F., Heldner, M. R., Zuurbier, S. M., . . . Tatlisumak, T. (2022). Dural arteriovenous fistulas in cerebral venous thrombosis: Data from the International Cerebral Venous Thrombosis Consortium. European Journal of Neurology, 29(3), 761-770. DOI Scopus1 WoS1
2022	Yassi, N., Zhao, H., Churilov, L., Campbell, B. C. V., Wu, T., Ma, H., . . . Davis, S. M. (2022). Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial. Stroke and vascular neurology, 7(2), 158-165. DOI Scopus2 WoS2 Europe PMC2
2022	Jacob, M. A., Ekker, M. S., Allach, Y., Cai, M., Aarnio, K., Arauz, A., . . . De Leeuw, F. E. (2022). Global Differences in Risk Factors, Etiology, and Outcome of Ischemic Stroke in Young Adults-A Worldwide Meta-analysis. Neurology, 98(6), E573-E588. DOI Scopus2 WoS2 Europe PMC1
2022	Sarraj, A., Albers, G. W., Blasco, J., Arenillas, J. F., Ribo, M., Hassan, A. E., . . . PERFECT-MILD Collaborators. (2022). Thrombectomy vs Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort. Annals of Neurology, 92(3), 364-378. DOI Scopus1 WoS1
2022	Scutelnic, A., Krzywicka, K., Mbroh, J., van de Munckhof, A., van Kammen, M. S., de Sousa, D. A., . . . Tatlisumak, T. (2022). Management of Cerebral Venous Thrombosis Due to Adenoviral COVID-19 Vaccination. Annals of Neurology, 92(4), 12 pages. DOI Scopus1 WoS1
2022	Gall, S., Feigin, V. L., Thrift, A. G., Kleinig, T., Cadilhac, D., Bennett, D., . . . Krishnamurthi, R. (2022). Personalised knowledge to reduce the risk of stroke (PERKS-International): protocol for a randomised controlled trial. International Journal of Stroke, 7 pages. DOI
2022	Mitchell, P. J., Yan, B., Churilov, L., Dowling, R. J., Bush, S. J., Bivard, A., . . . DIRECT-SAFE Investigators. (2022). Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial. Lancet (London, England), 400(10346), 116-125. DOI Scopus4 WoS4
2022	Garcia-Esperon, C., Bivard, A., Johns, H., Chen, C., Churilov, L., Lin, L., . . . INSPIRE Study group. (2022). Association of Endovascular Thrombectomy With Functional Outcome in Patients With Acute Stroke With a Large Ischemic Core.. Neurology, 10.1212/WNL.0000000000200908. DOI
2022	Bacchi, S., Oakden-Rayner, L., Menon, D. K., Moey, A., Jannes, J., Kleinig, T., & Koblar, S. (2022). Prospective and external validation of stroke discharge planning machine learning models. Journal of Clinical Neuroscience, 96, 80-84. DOI
2021	Gao, L., Bivard, A., Parsons, M., Spratt, N. J., Levi, C., Butcher, K., . . . Moodie, M. (2021). Real-world cost-effectiveness of late time window thrombectomy for patients With ischemic stroke. Frontiers in Neurology, 12, 1-9. DOI
2021	Noubiap, J. J., Feteh, V. F., Middeldorp, M. E., Fitzgerald, J. L., Thomas, G., Kleinig, T., . . . Sanders, P. (2021). A meta-analysis of clinical risk factors for stroke in anticoagulant-naïve patients with atrial fibrillation. EP-Europace, 23(10), 1528-1538. DOI Scopus3 WoS7 Europe PMC2
2021	Ng, F. C., Churilov, L., Yassi, N., Kleinig, T. J., Thijs, V., Wu, T., . . . Campbell, B. (2021). Prevalence and Significance of Impaired Microvascular Tissue Reperfusion Despite Macrovascular Angiographic Reperfusion (No-Reflow). Neurology, 98(8), e790-e801. DOI Scopus6 WoS5
2021	Ng, F. C., Churilov, L., Yassi, N., Kleinig, T. J., Thijs, V., Wu, T. Y., . . . EXTEND-IA TNK Part 1 and 2 Investigators. (2021). Microvascular Dysfunction in Blood-Brain Barrier Disruption and Hypoperfusion Within the Infarct Posttreatment Are Associated With Cerebral Edema. Stroke, 53(5), 1597-1605. DOI Scopus6 WoS8
2021	De Sciscio, M., De Sciscio, P., Vallat, W., & Kleinig, T. (2021). Cerebral microbleed distribution following cardiac surgery can mimic cerebral amyloid angiopathy. BMJ Neurology Open, 3(2), e000166. DOI Scopus2 Europe PMC1
2021	Bacchi, S., Gluck, S., Koblar, S., Jannes, J., & Kleinig, T. (2021). Improving the accuracy of stroke clinical coding with open-source software and natural language processing. Journal of Clinical Neuroscience, 94, 233-236. DOI
2021	Mahawish, K., Gommans, J., Kleinig, T., Lallu, B., Tyson, A., & Ranta, A. (2021). Switching to Tenecteplase for Stroke Thrombolysis: Real-World Experience and Outcomes in a Regional Stroke Network. Stroke, 52(10), E590-E593. DOI Scopus6 WoS5 Europe PMC1
2021	Bivard, A., Levi, C., Lin, L., Cheng, X., Aviv, R., Spratt, N. J., . . . Parsons, M. (2021). Assessing the Relative Value of CT Perfusion Compared to Non-contrast CT and CT Angiography in Prognosticating Reperfusion-Eligible Acute Ischemic Stroke Patients. Frontiers in Neurology, 12, 736768. DOI Scopus1
2021	Sánchez Van Kammen, M., Aguiar De Sousa, D., Poli, S., Cordonnier, C., Heldner, M. R., Van De Munckhof, A., . . . Bandettini Di Poggio, M. (2021). Characteristics and Outcomes of Patients with Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia. JAMA Neurology, 78(11), 1314-1323. DOI Scopus36 Europe PMC19
2021	Ng, F. C., Churilov, L., Yassi, N., Kleinig, T. J., Thijs, V., Wu, T. Y., . . . Campbell, B. C. (2021). Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke. Journal of Cerebral Blood Flow and Metabolism, 41(11), 271678X211017696-1-271678X211017696-11. DOI Scopus4 WoS4
2021	Zhao, H., Smith, K., Bernard, S., Stephenson, M., Ma, H., Chandra, R. V., . . . Campbell, B. C. V. (2021). Utility of Severity-Based Prehospital Triage for Endovascular Thrombectomy: ACT-FAST Validation Study. Stroke, 52(1), 70-79. DOI Scopus3 WoS6 Europe PMC1
2021	Alemseged, F., Ng, F. C., Williams, C., Puetz, V., Boulouis, G., Kleinig, T. J., . . . BATMAN study group EXTEND IA TNK study group. (2021). Tenecteplase versus alteplase before endovascular therapy in basilar artery occlusion. Neurology, 96(9), e1272-e1277. DOI Scopus12 WoS13 Europe PMC7
2021	Nogueira, R. G., Abdalkader, M., Qureshi, M. M., Frankel, M. R., Mansour, O. Y., Yamagami, H., . . . Novakovic-White, R. (2021). Global impact of COVID-19 on stroke care. International Journal of Stroke, 16(5), 573-584. DOI Scopus52 WoS41 Europe PMC24
2021	Chen, C., Parsons, M. W., Levi, C. R., Spratt, N. J., Lin, L., Kleinig, T., . . . Bivard, A. (2021). What is the “optimal” target mismatch criteria for acute ischemic stroke?. Frontiers in Neurology, 11, 1-11. DOI WoS1 Europe PMC1
2021	Hordacre, B., Austin, D., Brown, K. E., Graetz, L., Pareés, I., De Trane, S., . . . Rothwell, J. C. (2021). Evidence for a window of enhanced plasticity in the human motor cortex following ischemic stroke. Neurorehabilitation and Neural Repair, 35(4), 307-320. DOI Scopus6 WoS7 Europe PMC2
2021	Bacchi, S., Gluck, S., Tan, Y., Chim, I., Cheng, J., Gilbert, T., . . . Koblar, S. (2021). Mixed-data deep learning in repeated predictions of general medicine length of stay: a derivation study. Internal and Emergency Medicine, 16(6), 1613-1617. DOI Scopus4 WoS4 Europe PMC3
2021	Boyd, C., Brown, G., Kleinig, T., Dawson, J., McDonnell, M. D., Jenkinson, M., & Bezak, E. (2021). Machine Learning Quantitation of Cardiovascular and Cerebrovascular Disease: A Systematic Review of Clinical Applications. Diagnostics, 11(3), 1-23. DOI Scopus5 WoS2 Europe PMC1
2021	Cadilhac, D. A., Kim, J., Tod, E. K., Morrison, J. L., Breen, S. J., Jaques, K., . . . Campbell, B. C. V. (2021). COVID-19 pandemic impact on care for stroke in Australia: emerging evidence from the Australian Stroke Clinical Registry. Frontiers in Neurology, 12, 9 pages. DOI Scopus5 WoS5 Europe PMC2
2021	Nogueira, R. G., Qureshi, M. M., Abdalkader, M., Martins, S. O., Yamagami, H., Qiu, Z., . . . Yazawa, Y. (2021). Global Impact of COVID-19 on Stroke Care and IV Thrombolysis. Neurology, 96(23), e2824-e2838. DOI Scopus39 Europe PMC26
2021	Noubiap, J. J., Agbaedeng, T. A., Kamtchum-Tatuene, J., Fitzgerald, J. L., Middeldorp, M. E., Kleinig, T., & Sanders, P. (2021). Rhythm monitoring strategies for atrial fibrillation detection in patients with cryptogenic stroke: A systematic review and meta-analysis. IJC Heart and Vasculature, 34, 1-8. DOI Scopus5 Europe PMC2
2021	Sarraj, A., Campbell, B., Ribo, M., Hussain, M. S., Chen, M., Abraham, M. G., . . . Albers, G. W. (2021). SELECTion criteria for large core trials: Dogma or data?. Journal of NeuroInterventional Surgery, 13(6), 500-504. DOI Scopus7 WoS7 Europe PMC2
2021	Balabanski, A. H., Dos Santos, A., Woods, J. A., Thrift, A. G., Kleinig, T. J., Suchy-Dicey, A., . . . Katzenellenbogen, J. M. (2021). The incidence of stroke in Indigenous populations of countries with a Very High Human Development Index: a systematic review protocol. Frontiers in Neurology, 12, 661570-1-661570-12. DOI Scopus1 WoS1
2020	Pandos, O. C., Milton, A. G., Nagpal, A., Kleinig, T. J., Jannes, J., Koblar, S. A., & Hamilton-Bruce, M. A. (2020). Stroke Unit Legislation – Mandating a Uniform Standard of Care?. International Journal of Stroke, 15(2), NP6-NP7. DOI Scopus1
2020	Bacchi, S., Gluck, S., Tan, Y., Chim, I., Cheng, J., Gilbert, T., . . . Koblar, S. (2020). Prediction of general medical admission length of stay with natural language processing and deep learning: a pilot study.. Intern Emerg Med, 15(6), 989-995. DOI Scopus13 WoS14 Europe PMC8
2020	Meretoja, A., Yassi, N., Wu, T. Y., Churilov, L., Sibolt, G., Jeng, J. -S., . . . Davis, S. M. (2020). Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre, randomised, placebo-controlled, phase 2 trial. The Lancet Neurology, 19(12), 980-987. DOI Scopus34 WoS36 Europe PMC22
2020	Campbell, B. C. V., Ma, H., Parsons, M. W., Churilov, L., Yassi, N., Kleinig, T. J., . . . Davis, S. M. (2020). Association of reperfusion after thrombolysis with clinical outcome across the 4.5- to 9-hours and wake-up stroke time window: a meta-analysis of the EXTEND and EPITHET randomized clinical trials. JAMA Neurology, 78(2), 236-240. DOI Scopus6 WoS7 Europe PMC1
2020	Thomalla, G., Boutitie, F., Ma, H., Koga, M., Ringleb, P., Schwamm, L. H., . . . Cogez, J. (2020). Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data. The Lancet, 396(10262), 1574-1584. DOI Scopus47 WoS43 Europe PMC19
2020	Lillicrap, T., Keragala, C. B., Draxler, D. F., Chan, J., Ho, H., Harman, S., . . . Medcalf, R. L. (2020). Plasmin generation potential and recanalization in acute ischaemic stroke; an observational cohort study of stroke biobank samples. Frontiers in Neurology, 11, 589628-1-589628-4. DOI Scopus2 WoS2 Europe PMC1
2020	Gao, L., Tan, E., Moodie, M., Parsons, M., Spratt, N. J., Levi, C., . . . Bivard, A. (2020). Reduced impact of endovascular thrombectomy on disability in real-world practice, relative to randomized controlled trial evidence in Australia. Frontiers in Neurology, 11, 593238-1-593238-9. DOI Scopus1 WoS1
2020	Campbell, B. C. V., Mitchell, P. J., Churilov, L., Yassi, N., Kleinig, T. J., Yan, B., . . . Davis, S. M. (2020). Determining the optimal dose of tenecteplase before endovascular therapy for ischemic stroke (EXTEND-IA TNK Part 2): A multicenter, randomized, controlled study. International Journal of Stroke, 15(5), 567-572. DOI Scopus6 WoS6 Europe PMC4
2020	Abbott, A. L., Brunser, A. M., Giannoukas, A., Harbaugh, R. E., Kleinig, T., Lattanzi, S., . . . Topakian, R. (2020). Misconceptions regarding the adequacy of best medical intervention alone for asymptomatic carotid stenosis. Journal of Vascular Surgery, 71(1), 257-269. DOI Scopus34 WoS33 Europe PMC4
2020	Bacchi, S., Zerner, T., Oakden-Rayner, L., Kleinig, T., Patel, S., & Jannes, J. (2020). Deep Learning in the Prediction of Ischaemic Stroke Thrombolysis Functional Outcomes: A Pilot Study. Academic Radiology, 27(2), e19-e23. DOI Scopus23 WoS20 Europe PMC6
2020	Campbell, B. C., Mitchell, P. J., Churilov, L., Yassi, N., Kleinig, T. J., Dowling, R. J., . . . EXTEND-IA TNK Part 2 investigators. (2020). Effect of intravenous tenecteplase dose on cerebral reperfusion before thrombectomy in patients with large vessel occlusion ischemic stroke: the EXTEND-IA TNK part 2 randomized clinical trial. JAMA, 323(13), 1257-1265. DOI Scopus66 WoS71 Europe PMC21
2020	Hill, M. D., Goyal, M., Menon, B. K., Nogueira, R. G., McTaggart, R. A., Demchuk, A. M., . . . Alsultan, A. (2020). Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. The Lancet, 395(10227), 878-887. DOI Scopus198 WoS208 Europe PMC96
2020	Chabriat, H., Bassetti, C. L., Marx, U., Audoli-Inthavong, M. L., Sors, A., Lambert, E., . . . WEIN, T. (2020). Safety and efficacy of GABA<inf>A</inf> α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial. The Lancet Neurology, 19(3), 226-233. DOI Scopus16 WoS16 Europe PMC7
2020	Beharry, J., Waters, M. J., Drew, R., Fink, J. N., Wilson, D., Campbell, B. C. V., . . . Wu, T. Y. (2020). Dabigatran Reversal before Intravenous Tenecteplase in Acute Ischemic Stroke. Stroke, 51(5), 1616-1619. DOI Scopus11 WoS12 Europe PMC6
2020	Holliday, E., Lillicrap, T., Kleinig, T., Choi, P. M. C., Maguire, J., Bivard, A., . . . Levi, C. (2020). Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study. BMJ Open, 10(4), e038180-1-e038180-7. DOI Scopus1 WoS2
2020	Abbott, A. L., Brunser, A. M., Giannoukas, A., Harbaugh, R. E., Kleinig, T., Lattanzi, S., . . . Topakian, R. (2020). Reply. Journal of Vascular Surgery, 72(1), 384-385. DOI
2020	Abbott, A. L., Brunser, A. M., Giannoukas, A., Harbaugh, R. E., Kleinig, T., Lattanzi, S., . . . Topakian, R. (2020). Rectifying the misconceptions about current best management of asymptomatic carotid stenosis is not about revising history. Journal of Vascular Surgery, 72(2), 765-767. DOI
2020	Diener, H. C., Sacco, R. L., Easton, J. D., Granger, C. B., Bar, M., Bernstein, R. A., . . . Schäbitz, W. R. (2020). Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups. Stroke, 51(6), 1758-1765. DOI Scopus15 WoS13 Europe PMC4
2020	Bivard, A., Kleinig, T., Churilov, L., Levi, C., Lin, L., Cheng, X., . . . Parsons, M. (2020). Permeability measures predict hemorrhagic transformation after ischemic stroke. Annals of Neurology, 88(3), 466-476. DOI Scopus11 WoS11 Europe PMC5
2020	Hankey, G. J., Hackett, M. L., Almeida, O. P., Flicker, L., Mead, G. E., Dennis, M. S., . . . Dao, P. V. (2020). Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial. The Lancet Neurology, 19(8), 651-660. DOI Scopus58 WoS54 Europe PMC21
2020	Bacchi, S., Oakden-Rayner, L., Menon, D. K., Jannes, J., Kleinig, T., & Koblar, S. (2020). Stroke prognostication for discharge planning with machine learning: A derivation study. Journal of Clinical Neuroscience, 79, 100-103. DOI Scopus7 WoS8 Europe PMC5
2020	Lindgren, E., Silvis, S. M., Hiltunen, S., Heldner, M. R., Serrano, F., de Scisco, M., . . . Jood, K. (2020). Acute symptomatic seizures in cerebral venous thrombosis. Neurology, 95(12), e1706-e1715. DOI Scopus20 WoS23 Europe PMC7
2020	Lim, A., Singhal, S., Lavallee, P., Amarenco, P., Rothwell, P. M., Albers, G., . . . Phan, T. (2020). An International Report on the Adaptations of Rapid Transient Ischaemic Attack Pathways During the COVID-19 Pandemic. Journal of Stroke and Cerebrovascular Diseases, 29(11), 8 pages. DOI Scopus1 WoS1
2020	Gao, L., Moodie, M., Mitchell, P. J., Churilov, L., Kleinig, T. J., Yassi, N., . . . EXTEND-IA TNK Investigators. (2020). Cost-effectiveness of tenecteplase before thrombectomy for ischemic stroke. Stroke, 51(12), 3681-3689. DOI Scopus9 WoS9 Europe PMC3
2020	Balabanski, A. H., Goldsmith, K., Giarola, B., Buxton, D., Castle, S., McBride, K., . . . Kleinig, T. J. (2020). Stroke incidence and subtypes in Aboriginal people in remote Australia: a healthcare network population-based study.. BMJ open, 10(10), e039533. DOI Scopus6 WoS5 Europe PMC1
2020	Noubiap, J. J., Agbaedeng, T. A., Tochie, J. N., Nkeck, J. R., Ndoadoumgue, A. L., Fitzgerald, J. L., . . . Sanders, P. (2020). Meta-analysis comparing the frequency of carotid artery stenosis in patients with atrial fibrillation and vice versa. The American Journal of Cardiology, 138, 72-79. DOI Scopus6 WoS7
2019	Bacchi, S., Oakden-Rayner, L., Zerner, T., Kleinig, T., Patel, S., & Jannes, J. (2019). Deep learning natural language processing successfully predicts the cerebrovascular cause of transient ischemic attack-like presentations. Stroke, 50(3), 758-760. DOI Scopus25 WoS20 Europe PMC6
2019	Tian, H., Parsons, M. W., Levi, C. R., Lin, L., Aviv, R. I., Spratt, N. J., . . . Bivard, A. (2019). Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke. Neurology, 92(23), e2626-e2643. DOI Scopus19 WoS21 Europe PMC7
2019	Campbell, B., Majoie, C., Albers, G., Menon, B., Yassi, N., Sharma, G., . . . Stijnen, T. (2019). Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. The Lancet Neurology, 18(1), 46-55. DOI Scopus176 WoS168 Europe PMC63
2019	Silvis, S. M., Lindgren, E., Hiltunen, S., Devasagayam, S., Scheres, L. J., Jood, K., . . . Coutinho, J. M. (2019). Postpartum period is a risk factor for cerebral venous thrombosis: A case-control study. Stroke, 50(2), 501-503. DOI Scopus22 WoS24 Europe PMC11
2019	Alemseged, F., Shah, D., Bivard, A., Kleinig, T., Yassi, N., Diomedi, M., . . . Campbell, B. (2019). Cerebral blood volume lesion extent predicts functional outcome in patients with vertebral and basilar artery occlusion. International Journal of Stroke, 14(5), 540-547. DOI Scopus18 WoS17 Europe PMC7
2019	Ma, H., Campbell, B., Parsons, M., Churilov, L., Levi, C., Hsu, C., . . . Donnan, G. (2019). Thrombolysis guided by perfusion imaging up to 9 Hours after onset of stroke. The New England Journal of Medicine, 380(19), 1795-1803. DOI Scopus385 WoS372 Europe PMC129
2019	Alemseged, F., Van der Hoeven, E., Di Giuliano, F., Shah, D., Sallustio, F., Arba, F., . . . Fifi, J. (2019). Response to late-window endovascular revascularization is associated with collateral status in basilar artery occlusion. Stroke, 50(6), 1415-1422. DOI Scopus32 WoS33 Europe PMC5
2019	Campbell, B., Ma, H., Ringleb, P., Parsons, M., Churilov, L., Bendszus, M., . . . Simpson, M. (2019). Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. The Lancet, 394(10193), 139-147. DOI Scopus218 WoS208 Europe PMC66
2019	Chen, C., Parsons, M. W., Levi, C. R., Spratt, N. J., Miteff, F., Lin, L., . . . Bivard, A. (2019). Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis. Neurology, 93(3), E283-E292. DOI Scopus10 WoS10 Europe PMC2
2019	Mahadevan, J., Bacchi, S., Kiley, M., Moore, L., Manudhane, R., Pal, M., . . . Kleinig, T. (2019). Paediatric acute lymphoblastic leukaemia causing acute leukaemic occlusion of the proximal middle cerebral artery: Treatment with endovascular thrombectomy. Journal of Clinical Neuroscience, 68, 336-338. DOI Scopus3 WoS3 Europe PMC1
2019	Ekker, M., Jacob, M., Van Dongen, M., Aarnio, K., Annamalai, A., Arauz, A., . . . De Leeuw, F. E. (2019). Global Outcome Assessment Life-long after stroke in young adults initiative - The GOAL initiative: Study protocol and rationale of a multicentre retrospective individual patient data meta-analysis. BMJ Open, 9(11), 10 pages. DOI Scopus4 WoS3 Europe PMC1
2018	Zuurbier, S. M., Hiltunen, S., Lindgren, E., Silvis, S. M., Jood, K., Devasagayam, S., . . . Coutinho, J. M. (2018). Cerebral Venous Thrombosis in Older Patients.. Stroke, 49(1), 197-200. DOI Scopus17 WoS16 Europe PMC5
2018	Campbell, B., Mitchell, P., Churilov, L., Yassi, N., Kleinig, T., Yan, B., . . . Davis, S. (2018). Tenecteplase versus alteplase before endovascular thrombectomy (EXTEND-IA TNK): multicenter, randomized, controlled study. International Journal of Stroke, 13(3), 328-334. DOI Scopus32 WoS30 Europe PMC20
2018	Cheong, E., Dodd, L., Smith, W., & Kleinig, T. (2018). Icatibant as a Potential Treatment of Life-Threatening Alteplase-Induced Angioedema. Journal of Stroke and Cerebrovascular Diseases, 27(2), e36-e37. DOI Scopus14 WoS11 Europe PMC3
2018	Campbell, B., van Zwam, W., Goyal, M., Menon, B., Dippel, D., Demchuk, A., . . . van der Heijden, E. (2018). Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. The Lancet Neurology, 17(1), 47-53. DOI Scopus135 WoS136 Europe PMC52
2018	Campbell, B., van Zwam, W., Goyal, M., Menon, B., Dippel, D., Demchuk, A., . . . van der Heijden, E. (2018). Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. The Lancet Neurology, 17(1), 47-53. DOI Scopus135 WoS136 Europe PMC52
2018	Waters, M., Cheong, E., Jannes, J., & Kleinig, T. (2018). Ischaemic stroke may symptomatically manifest as migraine aura. Journal of Clinical Neuroscience, 12, 37. DOI Scopus8 WoS8 Europe PMC3
2018	Kasner, S. E., Swaminathan, B., Lavados, P., Sharma, M., Muir, K., Veltkamp, R., . . . Baumgartner, P. (2018). Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial. The Lancet Neurology, 17(12), 1053-1060. DOI Scopus101 WoS99 Europe PMC26
2018	Román, L., Menon, B., Blasco, J., Hernández-Pérez, M., Dávalos, A., Majoie, C., . . . Brown, M. (2018). Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. The Lancet Neurology, 17(10), 895-904. DOI Scopus188 WoS195 Europe PMC58
2018	Giarola, B. F., Leyden, J., Castle, S., Jannes, J., Anderson, C., Newbury, J., & Kleinig, T. (2018). Transient Ischaemic Attack Rarely Precedes Stroke in a Cohort with Low Proportions of Large Artery Atherosclerosis: A Population-Based Study. Cerebrovascular Diseases Extra, 8(2), 101-105. DOI Scopus2
2018	Cheong, E., Toner, P., Dowie, G., Jannes, J., & Kleinig, T. (2018). Evaluation of a CTA-Triage Based Transient Ischemic Attack Service: A Retrospective Single Center Cohort Study. Journal of Stroke and Cerebrovascular Diseases, 27(12), 3436-3442. DOI Scopus6 WoS7 Europe PMC3
2018	Reeves, P., Edmunds, K., Levi, C., Lin, L., Cheng, X., Aviv, R., . . . Bivard, A. (2018). Cost-effectiveness of targeted thrombolytic therapy for stroke patients using multi-modal CT compared to usual practice. PLoS ONE, 13(10), e0206203-1-e0206203-11. DOI Scopus3 WoS4 Europe PMC2
2018	Waters, M. J., & Kleinig, T. (2018). Black-blood magnetic resonance imaging demonstrates varicella zoster vasculitis. Internal Medicine Journal, 48(11), 1408-1410. DOI Scopus4 WoS4 Europe PMC2
2018	Lin, L., Bivard, A., Kleinig, T., Spratt, N. J., Levi, C. R., Yang, Q., & Parsons, M. W. (2018). Correction for delay and dispersion results in more accurate cerebral blood flow ischemic core measurement in acute stroke. Stroke, 49(4), 924-930. DOI Scopus23 WoS23 Europe PMC6
2018	Campbell, B., Mitchell, P., Churilov, L., Yassi, N., Kleinig, T., Dowling, R., . . . Davis, S. (2018). Tenecteplase versus alteplase before thrombectomy for ischemic stroke. New England Journal of Medicine, 378(17), 1573-1582. DOI Scopus306 WoS301 Europe PMC112
2018	Balabanski, A., Newbury, J., Leyden, J., Arima, H., Anderson, C., Castle, S., . . . Kleinig, T. (2018). Excess stroke incidence in young Aboriginal people in South Australia: pooled results from two population-based studies. International Journal of Stroke, 13(8), 811-814. DOI Scopus17 WoS16 Europe PMC6
2018	Tian, H., Parsons, M. W., Levi, C. R., Cheng, X., Aviv, R. I., Spratt, N. J., . . . Bivard, A. (2018). Intravenous thrombolysis may not improve clinical outcome of acute ischemic stroke patients without a baseline vessel occlusion. Frontiers in Neurology, 9(JUN), 405-1-405-7. DOI Scopus4 WoS4 Europe PMC2
2017	Chen, C., Parsons, M. W., Clapham, M., Oldmeadow, C., Levi, C. R., Lin, L., . . . Bivard, A. (2017). Influence of penumbral reperfusion on clinical outcome depends on baseline ischemic core volume. Stroke, 48(10), 2739-2745. DOI Scopus12 WoS12 Europe PMC8
2017	Wai, K., Balabanski, A., Chia, N., & Kleinig, T. (2017). Reversible hemispheric hypoperfusion in two cases of SMART syndrome. Journal of Clinical Neuroscience, 43, 146-148. DOI Scopus13 WoS12 Europe PMC4
2017	Bivard, A., Levi, C., Lin, L., Cheng, X., Aviv, R., Spratt, N., . . . Parsons, M. (2017). Validating a predictive model of acute advanced imaging biomarkers in ischemic stroke. Stroke, 48(3), 645-650. DOI Scopus34 WoS32 Europe PMC17
2017	Campbell, B., Mitchell, P., Churilov, L., Keshtkaran, M., Hong, K., Kleinig, T., . . . Davis, S. (2017). Endovascular thrombectomy for ischemic stroke increases disability-free survival, quality of life, and life expectancy and reduces cost. Frontiers in Neurology, 8(DEC), 6570-1-657-17. DOI Scopus35 WoS33 Europe PMC9
2017	Goldfinch, A. I., & Kleinig, T. J. (2017). Stroke-like migraine attacks after radiation therapy syndrome: a case report and literature review. Radiology Case Reports, 12(3), 610-614. DOI Scopus6 Europe PMC5
2017	Bivard, A., Kleinig, T., Miteff, F., Butcher, K., Lin, L., Levi, C., & Parsons, M. (2017). Ischemic core thresholds change with time to reperfusion: A case control study. Annals of Neurology, 82(6), 995-1003. DOI Scopus58 WoS56 Europe PMC24
2017	Newbury, J., Kleinig, T., Leyden, J., Arima, H., Castle, S., Cranefield, J., . . . Anderson, C. (2017). Stroke Epidemiology in an Australian Rural Cohort (SEARCH). International Journal of Stroke, 12(2), 161-168. DOI Scopus23 WoS24 Europe PMC11
2017	Kleinig, T. (2017). Antihypertensive treatment should be commenced in hospital after stroke: Pro. International Journal of Stroke, 12(2), 121-122. DOI Scopus2 WoS3 Europe PMC1
2017	Waters, M., Kleinig, T., Cheong, E., & Jannes, J. (2017). Ischaemic stroke may symptomatically manifest as migraine aura. INTERNATIONAL JOURNAL OF STROKE, 12, 37.
2016	Bivard, A., Cheng, X., Lin, L., Levi, C., Spratt, N., Kleinig, T., . . . Parsons, M. (2016). Global white matter hypoperfusion on CT predicts larger infarcts and hemorrhagic transformation after acute ischemia. CNS Neuroscience and Therapeutics, 22(3), 238-243. DOI Scopus14 WoS14 Europe PMC8
2016	Chia, N., Leyden, J., Newbury, J., Jannes, J., & Kleinig, T. (2016). Determining the number of ischemic strokes potentially eligible for endovascular thrombectomy: a population-based study. Stroke, 47(5), 1377-1380. DOI Scopus89 WoS85 Europe PMC49
2016	Adey-Wakeling, Z., Liu, E., Crotty, M., Leyden, J., Kleinig, T., Anderson, C., & Newbury, J. (2016). Hemiplegic shoulder pain reduces quality of life after acute stroke: a prospective population-based study. American Journal of Physical Medicine and Rehabilitation, 95(10), 758-763. DOI Scopus31 WoS28 Europe PMC10
2016	Bivard, A., Lou, M., Levi, C. R., Krishnamurthy, V., Cheng, X., Aviv, R. I., . . . Parsons, M. W. (2016). Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis. Annals of Neurology, 80(2), 286-293. DOI Scopus24 WoS24 Europe PMC16
2016	Devasagayam, S., Wyatt, B., Leyden, J., & Kleinig, T. (2016). Cerebral Venous Sinus Thrombosis Incidence Is Higher Than Previously Thought: A Retrospective Population-Based Study. Stroke, 47(9), 2180-2182. DOI Scopus168 WoS139 Europe PMC73
2015	Carey, L., Crewther, S., Salvado, O., Lindén, T., Connelly, A., Wilson, W., . . . START Research Team. (2015). STroke imAging pRevention and treatment (START): a longitudinal stroke cohort study: clinical trials protocol. International Journal of Stroke, 10(4), 636-644. DOI Scopus17 WoS16 Europe PMC8
2015	Chia, N., & Kleinig, T. (2015). Complete reversibility of a 'malignant profile' left MCA territory stroke. International Journal of Stroke, 10(5), E46. DOI Scopus1 WoS1 Europe PMC1
2015	Borg, S., Tonkin, A., Kleinig, T., & Waters, M. (2015). Unusual presentation of Epstein-Barr virus encephalitis in an older patient with a dramatic clinical response to intravenous immunoglobulin. Internal Medicine Journal, 45(8), 879-881. DOI Scopus2 WoS2 Europe PMC2
2015	Adey-Wakeling, Z., Arima, H., Crotty, M., Leyden, J., Kleinig, T., Anderson, C., & Newbury, J. (2015). Incidence and associations of hemiplegic shoulder pain poststroke: prospective population-based study. Archives of Physical Medicine and Rehabilitation, 96(2), 241-247.e1. DOI Scopus55 WoS48 Europe PMC26
2015	Campbell, B., Mitchell, P., Kleinig, T., Dewey, H., Churilov, L., Yassi, N., . . . Davis, S. (2015). Endovascular therapy for ischemic stroke with perfusion-imaging selection. New England Journal of Medicine, 372(11), 1009-1018. DOI Scopus3708 WoS3518 Europe PMC2026
2015	CADISS trial investigators., Markus, H., Hayter, E., Levi, C., Feldman, A., Venables, G., . . . Delcourt, C. (2015). Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial. Lancet Neurology, 14(4), 361-367. DOI WoS270 Europe PMC155
2014	Paul, N., & Kleinig, T. (2014). Therapy of paraneoplastic disorders of the CNS. Expert Review of Neurotherapeutics, 15(2), 187-193. DOI Scopus6 WoS6 Europe PMC3
2014	Khurram, A., Kleinig, T., & Leyden, J. (2014). Clinical associations and causes of convexity subarachnoid hemorrhage. Stroke, 45(4), 1151-1153. DOI Scopus54 WoS50 Europe PMC30
2014	Chia, N., & Kleinig, T. (2014). Verapamil-responsive coital cephalalgia as reversible cerebral vasoconstriction prodrome. Journal of Neurology, 261(8), 1641-1643. DOI Scopus1 WoS1 Europe PMC1
2014	Campbell, B., Mitchell, P., Yan, B., Parsons, M., Christensen, S., Churilov, L., . . . Davis, S. (2014). A multicenter, randomized, controlled study to investigate EXtending the time for thrombolysis in emergency neurological deficits with intra-arterial therapy (EXTEND-IA). International Journal of Stroke, 9(1), 126-132. DOI Scopus114 WoS103 Europe PMC63
2014	Meretoja, A., Churilov, L., Campbell, B., Aviv, R., Yassi, N., Barras, C., . . . Davis, S. (2014). The Spot sign and Tranexamic acid On Preventing ICH growth - AUStralasia Trial (STOP-AUST): Protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial. International Journal of Stroke, 9(4), 519-524. DOI Scopus58 WoS50 Europe PMC30
2014	Barber, P., & Kleinig, T. (2014). INTERACT2: a reason for optimism with spontaneous intracerebral hemorrhage?. International Journal of Stroke, 9(1), 59-60. DOI Scopus3 WoS3 Europe PMC1
2013	Tidswell, J., Kleinig, T., Ash, D., Thompson, P., & Galletly, C. (2013). Early recognition of anti-N-methyl D-aspartate (Nmda) receptor encephalitis presenting as acute psychosis. Australasian Psychiatry, 21(6), 596-599. DOI Scopus12 WoS10 Europe PMC8
2013	Kleinig, T. (2013). Associations and implications of cerebral microbleeds. Journal of Clinical Neuroscience, 20(7), 919-927. DOI Scopus15 WoS14 Europe PMC10
2013	Leyden, J., Kleinig, T., Newbury, J., Castle, S., Cranefield, J., Anderson, C., . . . Greenhill, J. (2013). Adelaide Stroke Incidence Study: declining stroke rates but many preventable cardioembolic strokes. Stroke, 44(5), 1226-1231. DOI Scopus108 WoS104 Europe PMC72
2013	Abbott, A., & Kleinig, T. (2013). Why calls for more routine carotid stenting are currently inappropriate: an international, multispecialty, expert review and position statement. Stroke, 44(4), 1186-1190. DOI Scopus49 WoS38 Europe PMC26
2013	Kleinig, T. (2013). Mesiotemporal neuroimaging abnormalities in neurosyphilis and other causes of limbic encephalitis. Internal Medicine Journal, 43(4), 470. DOI Scopus2 WoS1 Europe PMC1
2013	Yang, J., Zhao, K., Sun, J., Yang, W., Qiu, Y., Kleinig, T., . . . Chen, S. (2013). Comparison between the formula 1/2ABC and 2/3Sh in intracerebral parenchyma hemorrhage. Neurological Research, 35(4), 382-388. DOI Scopus8 WoS7 Europe PMC4
2013	Vallat, W., Maundrell, A., Leyden, J., & Kleinig, T. J. (2013). Cerebral amyloid angiopathy causing cortical microinfarction. Journal of Clinical Neuroscience, 20(12), 1802-1804. DOI Scopus2 WoS4 Europe PMC2
2013	Kleinig, T. J., Churilov, L., Parsch, C. S., Dewey, H. M., & Barber, P. A. (2013). Stroke thrombolysis and the third international stroke trial: examining 'the totality of the evidence'. Emergency Medicine Australasia, 25(2), 107-109. DOI Scopus3 WoS3 Europe PMC3
2013	Butt, S., Vatandoust, S., Kleinig, T., Adams, J., Basu, S., Otto, G., & Joshi, R. (2013). Anti-Ri antibody-associated paraneoplastic brainstem encephalitis successfully treated after treating the underlying malignancy with letrozole. Internal Medicine Journal, 2013(5), 605-606. DOI Scopus2 WoS2
2013	Vallat, W., Maundrell, A., Leyden, J., & Kleinig, T. (2013). Cerebral amyloid angiopathy causing cortical microinfarction. Journal of Clinical Neuroscience, 20(12), 1802-1804. DOI Scopus4
2012	Abbott, A. L., Adelman, M. A., Alexandrov, A. V., Barnett, H. J. M., Beard, J., Bell, P., . . . Zhou, W. (2012). Why the United States Center for Medicare and Medicaid Services (CMS) should not extend reimbursement indications for carotid artery angioplasty/stenting (International Angiology 31, 1 (85-89)). International Angiology, 31(3), 305.
2012	Irani, S. R., Alexander, S., & Vincent, A. (2012). Case 34-2011: A Man with Memory Loss and Partial Seizures. NEW ENGLAND JOURNAL OF MEDICINE, 366(8), 768-769. DOI
2012	Abbott, A. L., Adelman, M. A. A., Alexandrov, A. V., Barnett, H. J. M., Beard, J., Bell, P., . . . Zhou, W. (2012). Why the United States Center for Medicare and Medicaid Services (CMS) should not extend reimbursement indications for carotid artery angioplasty/stenting. Brain and Behavior, 2(2), 200-207. DOI Scopus4 WoS3
2012	Abbott, A. L., Adelman, M. A., Alexandrov, A. V., Barnett, H. J. M., Beard, J., Bell, P., . . . Zhou, W. (2012). Why the United States Center for Medicare and Medicaid Services (CMS) should not extend reimbursement indications for carotid artery angioplasty/stenting. European Journal of Vascular and Endovascular Surgery, 43(3), 247-251. DOI Scopus18 WoS18 Europe PMC10
2012	Beadnall, H., Kiley, M., & Kleinig, T. (2012). Case 34-2011: a man with memory loss and partial seizures. New England Journal of Medicine, 366(8), 768. DOI
2012	Abbott, A. L., Adelman, M. A., Alexandrov, A. V., Barnett, H. J. M., Beard, J., Bell, P., . . . Zhou, W. (2012). Why the United States Center for Medicare and Medicaid Services should not extend reimbursement indications for carotid artery angioplasty/stenting. Vascular, 20(1), 1-7. DOI Scopus1 WoS1 Europe PMC1
2012	Abbott, A. L., Adelman, M. A., Alexandrov, A. V., Barnett, H. J. M., Beard, J., Bell, P., . . . Zhou, W. (2012). Why the United States Center for Medicare and Medicaid Services (CMS) should not extend reimbursement indications for carotid artery angioplasty/stenting. International Angiology, 31(1), 85-90. Scopus2 WoS3 Europe PMC1
2012	Ma, H., Parsons, M., Christensen, S., Campbell, B., Churilov, L., Connelly, A., . . . Donnan, G. (2012). A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND). International Journal of Stroke, 7(1), 74-80. DOI Scopus160 WoS142 Europe PMC106
2012	Abbott, A., & Kleinig, T. (2012). Why the US center for Medicare and Medicaid services should not extend reimbursement indications for carotid artery angioplasty/stenting. Angiology, 63(8), 639-644. DOI Scopus4 WoS4 Europe PMC3
2012	Helps, S., Thornton, E., Kleinig, T., Manavis, J., & Vink, R. (2012). Automatic nonsubjective estimation of antigen content visualized by immunohistochemistry using color deconvolution. Applied Immunohistochemistry and Molecular Morphology, 20(1), 82-90. DOI Scopus54 WoS50 Europe PMC35
2011	Phillips, M., Leyden, J., Chong, W., Kleinig, T., Czapran, P., Lee, A., . . . Jannes, J. (2011). Ischaemic stroke among young people aged 15 to 50 years in Adelaide, South Australia. Medical Journal of Australia, 195(10), 610-614. DOI Scopus29 WoS27 Europe PMC19
2011	Field, D., & Kleinig, T. (2011). Aura attacks from acute convexity subarachnoid haemorrhage not due to cerebral amyloid angiopathy. Cephalalgia, 31(3), 368-371. DOI Scopus13 WoS10 Europe PMC7
2011	Leyden, J., Chong, W., Kleinig, T., Lee, A., Field, J., & Jannes, J. (2011). A population-based study of thrombolysis for acute stroke in South Australia. Medical Journal of Australia, 194(3), 111-115. DOI Scopus18 WoS19 Europe PMC12
2011	Kleinig, T. J., Brophy, B. P., & Maher, C. G. (2011). Back pain and leg weakness. Medical Journal of Australia, 195(8), 454-457. DOI Scopus6 WoS4 Europe PMC4
2011	Kleinig, T., Leyden, J., Lee, A., & Jannes, J. (2011). RE: A population-based study of thrombolysis for acute stroke in south australia. Medical Journal of Australia, 194(8), 432.
2011	Kleinig, T., Leyden, J. M., Lee, A., & Jannes, J. (2011). A population-based study of thrombolysis for acute stroke in South Australia Reply. MEDICAL JOURNAL OF AUSTRALIA, 194(8), 431-432. DOI
2010	Field, D., Kleinig, T., Thompson, P., & Kimber, T. (2010). Reversible cerebral vasoconstriction, internal carotid artery dissection and renal artery stenosis. Cephalalgia, 30(8), 983-986. DOI Scopus12 WoS9 Europe PMC7
2010	Cook, N., Kleinig, T., Van Den Heuvel, C., & Vink, R. (2010). Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage. BMC Molecular Biology, 11(1), 1-11. DOI Scopus15 WoS15 Europe PMC14
2010	Ghali, J., Allison, D., Kleinig, T., Ooi, S., Bastiampillai, S., Ashby, D., . . . Broadley, S. (2010). Elevated serum concentrations of troponin T in acute stroke: What do they mean?. Journal of Clinical Neuroscience, 17(1), 69-73. DOI Scopus10 WoS8 Europe PMC6
2009	Kleinig, T., Kimber, T., & Thompson, P. (2009). Stroke prevention and stroke thrombolysis: quantifying the potential benefits of best practice therapies. Medical Journal of Australia, 190(12), 678-682. DOI Scopus3 WoS2 Europe PMC1
2009	Kleinig, T., Helps, S., Ghabriel, M., Manavis, J., Leigh, C., Blumbergs, P., & Vink, R. (2009). Hemoglobin crystals: A pro-inflammatory potential confounder of rat experimental intracerebral hemorrhage. Brain Research, 1287, 164-172. DOI Scopus16 WoS15 Europe PMC10
2009	Kumar, K., & Kleinig, T. (2009). Malignant ischaemic stroke of an entire cerebral hemisphere. Journal of Neurology Neurosurgery and Psychiatry, 80(1), 87. DOI Scopus1 WoS1 Europe PMC1
2009	Kleinig, T., Thompson, P., & Kneebone, C. (2009). Chorea, transverse myelitis, neuropathy and a distinctive MRI: Paraneoplastic manifestations of probable small cell lung cancer. Journal of Clinical Neuroscience, 16(7), 964-966. DOI Scopus8 WoS5 Europe PMC4
2009	Kleinig, T., & Vink, R. (2009). Suppression of inflammation in ischemic and hemorrhagic stroke: therapeutic options. Current Opinion in Neurology, 22(3), 294-301. DOI Scopus103 WoS98 Europe PMC65
2009	Kleinig, T., Koszyca, B., Blumbergs, P., & Thompson, P. (2009). Fulminant leucocytoclastic brainstem vasculitis in a patient with otherwise indolent systemic lupus erythematosus. Lupus, 18(6), 486-490. DOI Scopus10 WoS7 Europe PMC4
2009	Kleinig, T., Kimber, T., & Thompson, P. (2009). Convexity subarachnoid haemorrhage associated with bilateral internal carotid artery stenoses. Journal of Neurology, 256(4), 669-671. DOI Scopus30 WoS24 Europe PMC17
2008	Kleinig, T., Thompson, P., Walid, M., Duggins, A., Kimber, T., Morris, J., . . . Blumbergs, P. (2008). The distinctive movement disorder of ovarian teratoma-associated encephalitis. Movement Disorders, 23(9), 1256-1261. DOI Scopus116 WoS95 Europe PMC65
2008	Kleinig, T., Harley, H., & Thompson, P. (2008). Neurological deterioration during treatment in Wilson's disease: Question. Journal of Clinical Neuroscience, 15(5), 575. DOI Scopus2 WoS2 Europe PMC1
2008	Kleinig, T., Kiley, M., & Thompson, P. (2008). Acute convexity subarachnoid haemorrhage: a cause of aura-like symptoms in the elderly. Cephalalgia, 28(6), 658-663. DOI Scopus20 WoS18 Europe PMC14
2008	Fleury, V., Kleinig, T., Thompson, P., & Ravindran, J. (2008). Cardio-embolic cerebellar stroke secondary to mitral valve chordae rupture as a delayed complication of a high-voltage electrical injury. Journal of Clinical Neuroscience, 15(2), 210-212. DOI Scopus5 WoS6 Europe PMC3
2008	Leyden, J., & Kleinig, T. (2008). The role of the basal ganglia in data processing. Medical Hypotheses, 71(1), 61-64. DOI Scopus17 WoS17 Europe PMC14
2008	Kong, A., Kleinig, T., Van Der Vliet, A., Bergin, P., Coscia, C., Ring, S., & Brooder, R. (2008). MRI of sporadic Creutzfeldt-Jakob disease. Journal of Medical Imaging and Radiation Oncology, 52(4), 318-324. DOI Scopus6 WoS3 Europe PMC2
2007	Kleinig, T. J. (2007). Health effects of war are devastating: Pre-emptive war demands pre-emptive criticism by the medical profession [7]. Internal Medicine Journal, 37(8), 585. DOI Scopus1 WoS1 Europe PMC1
2007	Kleinig, T., Kimber, T., & Thompson, P. (2007). Acute encephalopathy as the initial symptom of CADASIL. Internal Medicine Journal, 37(11), 786-787. DOI Scopus6 WoS5 Europe PMC3
2006	Leong, D., Kleinig, T., Kimber, T., & Bardy, P. (2006). Severe hypermagnesaemia related to laxative use in acute gastrointestinal graft-versus-host disease. Bone Marrow Transplantation, 38(1), 71-72. DOI Scopus1 WoS3 Europe PMC3
2004	Kleinig, T., & Torpy, D. (2004). Milk-Alkali syndrome: broadening the spectrum of causes to allow early recognition. Internal Medicine Journal, 34(6), 366-NIL_2. DOI Scopus5 WoS6 Europe PMC5
	Ng, F., Churilov, L., Yassi, N., Kleinig, T., Thijs, V., Wu, T. Y., . . . Group, E. -I. T. N. K. P. 1. A. 2. I. (n.d.). Prevalence, Characteristics and Clinical Significance of Impaired Tissue Reperfusion Despite Complete Recanalization in Ischemic Stroke (No-Reflow): A Pooled Analysis of 3 Randomized Clinical Trials.

Book Chapters

Year	Citation
2015	Thompson, P., Kleinig, T., & Kimber, T. (2015). Myoclonus and asterixis. In J. Friedman (Ed.), Medication-Induced Movement Disorders (pp. 160-167). Cambridge: Cambridge University Press. DOI Scopus1
2008	Kleinig, T., & Thompson, P. (2008). A woman with recurrent ataxia and facial myoclonus. In Movement Disorders: 100 Instructive Cases (pp. 171-173).

Conference Papers

Year	Citation
2022	Yogendrakumar, V., Churilov, L., Mitchell, P. J., Kleinig, T. J., Yassi, N., Thijs, V., . . . Campbell, B. (2022). Safety Of Tenecteplase And Alteplase In Tandem Lesion Stroke: A Pooled Analysis Of The Extend-IA TNK Trials. In STROKE Vol. 53 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2022	Warach, S. J., Ranta, A., Song, S. S., Gibson, D., Wallace, A., Beharry, J., . . . Wu, T. Y. (2022). Comparative Effectiveness Of Routine Tenecteplase Thrombolysis In Acute Stroke Compared With Alteplase: An INternational Collaboration (CERTAIN Collaboration): Rates Of Symptomatic Intracranial Hemorrhage. In STROKE Vol. 53 (pp. 3 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2022	Sarraj, A., Albers, G., Hassan, A., Abraham, M. G., Blackburn, S., Hussain, M., . . . Campbell, B. C. (2022). The Effect Of Anesthesia On Thrombectomy Outcomes Is Modified By Collateral Flow: Pooled Patient Level Analysis From EXTEND-IA, EXTEND-IA TNK Part I And II, And SELECT. In STROKE Vol. 53 (pp. 3 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2022	Sarraj, A., Hassan, A. E., Abraham, M. G., Cardona Portela, P., Manning, N. W., Cordato, D., . . . Albers, G. W. (2022). Endovascular Thrombectomy Beyond 24 Hours From Last Known Well: A Pooled Multicenter International Cohort. In STROKE Vol. 53 (pp. 3 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2022	Mahadevan, J., Lui, M., Jin, A., Dixon, K., Jannes, J., Kurunawai, C., . . . Kleinig, T. (2022). A whole-of-state South Australian telestroke service shows sustained increase in reperfusion therapies; a population-based study. In INTERNATIONAL JOURNAL OF STROKE Vol. 17 (pp. 13). SAGE PUBLICATIONS LTD.
2022	Goh, R., Bacchi, S., Vallat, W., Schultz, D., Jannes, J., & Kleinig, T. (2022). Factors associated with delay to Carotid Endarterectomy for Acute Ischaemic Stroke in South Australia: A multicentre retrospective cohort study. In INTERNATIONAL JOURNAL OF STROKE Vol. 17 (pp. 10-11). SAGE PUBLICATIONS LTD.
2021	Ng, F., Sharma, G., Churilov, L., Yassi, N., Kleinig, T., Davis, S., . . . Campbell, B. (2021). Post-Treatment Blood-Brain Barrier Disruption is Associated With Cerebral Edema and Extends Into Penumbral Tissue in Anterior Circulation Large Vessel Occlusion.. In STROKE Vol. 52 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2021	Sarraj, A., Ribo, M., Blasco, J., Perez de la Ossa, N., Chen, M., Hassan, A. E., . . . Albers, G. (2021). Perfusion Imaging Identifies Patients With Mild Deficits Due to Large Vessel Occlusion Who May Benefit From Endovascular Thrombectomy: A Pooled International Cohort Study. In STROKE Vol. 52 (pp. 3 pages). LIPPINCOTT WILLIAMS & WILKINS. DOI
2021	Gupta, A. K., Sabab, A., Ovenden, C. D., & Kleinig, T. J. (2021). Endovascular clot retrieval for large vessel acute ischaemic stroke after cardiac surgery. In INTERNATIONAL JOURNAL OF STROKE Vol. 16 (pp. 11-12). SAGE PUBLICATIONS LTD.
2021	Robinson, K., Katzenellenbogen, J. M., Thrift, A. G., Budgeon, C., Kim, J., Kleinig, T. J., & Nedkoff, L. (2021). Risk of stroke onset in patients with incident cardiac disease. In INTERNATIONAL JOURNAL OF STROKE Vol. 16 (pp. 26). SAGE PUBLICATIONS LTD.
2019	Kleinig, T., Cheong, E., Harvey, J., Cagi, L., Cranefield, J., Koblar, S., . . . Campbell, B. (2019). Head-down position improves blood flow in acute stroke measured by CT perfusion (CTP): interim results of the Head-START study. In INTERNATIONAL JOURNAL OF STROKE Vol. 14 (pp. 4). SAGE PUBLICATIONS LTD.
2019	Trott, R., Kleinig, T., Hillier, S., Hobbs, D., & Reynolds, K. (2019). A Modular Hybrid Exoskeletal-Soft Glove for High Degree of Freedom Monitoring Capability. In Proceedings of the 2019 IEEE International Conference on Rehabilitation Robotics Vol. 2019 (pp. 577-582). online: IEEE. DOI Scopus1 WoS1
2018	De Sciscio, M., Kleinig, T., De Sciscio, P., & Jannes, J. (2018). Cortical cerebral microbleeds are common following cardiac surgery, especially valve replacement, however distribution ratio distinguishes from cerebral amyloid angiopathy. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 24). SAGE PUBLICATIONS LTD. DOI
2018	Lillicrap, T., Harman, S., Draxler, D., Niego, B., Ho, H., McCutcheon, F., . . . Medcalf, R. (2018). Ex-vivo generation of plasmin from patients with acute ischaemic stroke is predictive of successful thrombolysis. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 4). SAGE PUBLICATIONS LTD.
2018	Milton, A. G., Kleinig, T., Young, A. -M., Nagpal, A., Kim, S., Koblar, S. A., . . . Jannes, J. (2018). Central Adelaide Local Health Network - Stroke Unit Access Update. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 47). SAGE PUBLICATIONS LTD.
2018	Levi, C., Lillicrap, T., Harman, S., Draxler, D., Niego, B., Ho, H., . . . Medcalf, R. (2018). EX-VIVO GENERATION OF PLASMIN FROM PATIENTS WITH ACUTE ISCHAEMIC STROKE IS PREDICTIVE OF SUCCESSFUL THROMBOLYSIS. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 89 (pp. E6). Darwin, AUSTRALIA: BMJ PUBLISHING GROUP. DOI
2018	Harvey, J., Dodd, L., Hampton, C., Bronca, M., Laubscher, S., James, A., . . . Kleinig, T. (2018). Centralisation of Adelaide stroke services is associated with increased utilisation of endovascular thrombectomy, but no change in reperfusion time metrics. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 26). SAGE PUBLICATIONS LTD.
2018	Alemseged, F., Van der Hoeven, E., Di Giuliano, F., Shah, D., Yassi, N., Arba, F., . . . Campbell, B. (2018). Endovascular therapy in basilar artery occlusion: impact of time to treatment, collaterals and thrombus burden. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 23). SAGE PUBLICATIONS LTD.
2018	Mahadevan, J., Kleinig, T., & Jannes, J. (2018). Fat embolism: an important differential diagnosis to multi-embolic stroke following Coronary Artery Bypass grafting (CABG). In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 46). SAGE PUBLICATIONS LTD.
2018	Waters, M., & Kleinig, T. (2018). Black-Blood Magnetic Resonance Imaging Demonstrates Varicella Zoster Vasculitis. In INTERNATIONAL JOURNAL OF STROKE Vol. 13 (pp. 40). SAGE PUBLICATIONS LTD.
2018	Clarke, A., Vallat, W., & Kleinig, T. (2018). CEREBRAL FAT EMBOLISM IN A CASE OF ENDOSCOPIC OESOPHAGEAL DILATATION. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 89 (pp. E35). Darwin, AUSTRALIA: BMJ PUBLISHING GROUP. DOI
2018	Zuurbier, S., Hiltunen, S., Lindgren, E., Silvis, S., Jood, K., Devasagayam, S., . . . Coutinho, J. (2018). Cerebral Venous Thrombosis in Older Patients. In NEUROLOGY Vol. 90 (pp. 2 pages). Los Angeles, CA: LIPPINCOTT WILLIAMS & WILKINS.
2015	Moey, A., Hamilton-Bruce, M., Howell, S., Leyden, J., Chong, W., Dodd, L., . . . Jannes, J. (2015). Significant increase in thrombolysis therapy rates for stroke in South Australia. In International Journal of Stroke Vol. 10 (pp. E49). England: Wiley. DOI Scopus2 WoS4 Europe PMC2
2010	Kleinig, T. J., Helps, S. C., Cook, N., Blumbergs, P. C., & Vink, R. (2010). Inhibition of Substance P Reduces Edema and Blood-Brain Barrier Dysfunction Following Rat Collagenase Intracerebral Hemorrhage, but Does Not improve Functional Outcome. In STROKE Vol. 41 (pp. E212-E213). San Antonio, TX: LIPPINCOTT WILLIAMS & WILKINS. WoS1
2005	Kleinig, T. J. (2005). Acute encephalopathy as the initial symptom of CADASIL. In JOURNAL OF THE NEUROLOGICAL SCIENCES Vol. 238 (pp. S409-S410). Sydney, AUSTRALIA: ELSEVIER.
2005	Kleinig, T. J., Thompson, P. D., & Blumbergs, P. C. (2005). Unusual axonal bodies in autopsy-proven Hodgkin's disease-associated paraneoplastic limbic encephalitis. In JOURNAL OF THE NEUROLOGICAL SCIENCES Vol. 238 (pp. S273). Sydney, AUSTRALIA: ELSEVIER.
2005	Fleury, V., Kleinig, T., & Ravindran, J. (2005). Cardio-embolic cerebellar stroke secondary to mitral valve chordae tendinae rupture as a delayed complication of a high-voltage electrical injury. In JOURNAL OF THE NEUROLOGICAL SCIENCES Vol. 238 (pp. S397). Sydney, AUSTRALIA: ELSEVIER.

Conference Items

Year	Citation
2021	Bacchi, S., Oakden-Rayner, L., Menon, D. K., Moey, A., Jannes, J., Kleinig, T., & Koblar, S. (2021). STROKE PROGNOSTICATION FOR DISCHARGE PLANNING WITH MACHINE LEARNING: DERIVATION, PROSPECTIVE VALIDATION AND EXTERNAL VALIDATION. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY.
2020	Ng, F. C., Churilov, L., Yassi, N., Kleinig, T. J., Thijs, V., Wu, T. Y., . . . Campbell, B. C. V. (2020). Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies. Poster session presented at the meeting of International Journal of Stroke. Helsinki: SAGE Publications. DOI
2019	Jin, A., Dixon, K., Jannes, J., Kurunawai, C., Tan, A., Willcourt, M., & Kleinig, T. (2019). A South Australian whole-of-state tele stroke service increases rural population reperfusion therapy rates and decreases unnecessary metropolitan transfers. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2019	Waters, M., Scroop, R., Jin, A., Dixon, K., Willcourt, M., Jannes, J., . . . Kleinig, T. (2019). Pre-retrieval tenecteplase for large vessel occlusion stroke in a rural setting: real world experience. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2019	Milton, A., Harvey, J., Edwards, S., Young, A. -M., Dodd, L., Hampton, C., . . . Koblar, S. (2019). Central Adelaide Local Health Network (CALHN) Stroke Unit (SU) administrative data and Stroke Clinical Registry data analyses. Poster session presented at the meeting of International Journal of Stroke. Canberra, Australia: International Journal of Stroke.
2018	Vallat, W., & Kleinig, T. (2018). A 47-year old female with slowly progressive cognitive impairment and motor decline. Poster session presented at the meeting of Abstracts of the Annual Scientific Meeting of the Australian-and-New Zealand-Association-of-Neurologists, as published in Journal of Neurology, Neurosurgery and Psychiatry. Darwin, AUSTRALIA: BMJ Publishing Group. DOI
2017	Goldsmith, K., Balabanski, A., Giarola, B., Buxton, D., Castle, S., McBride, K., . . . Kleinig, T. (2017). Excessive stroke incidence in Aboriginal people in Central Australia: a retrospective population-based study. Poster session presented at the meeting of Abstracts of the RACP Congress 2017 - Bringing Specialists Together. Sharing Knowledge. Building Skills, as published in Internal Medicine Journal. Melbourne, VIC: Wiley-Blackwell. DOI WoS2
2017	Clarke, A., Vallat, W., & Kleinig, T. (2017). MULTIPLE BITHALAMIC MICROBLEEDS IN A CASE OF DEEP CEREBRAL DURAL ARTERIOVENOUS FISTULA. Poster session presented at the meeting of JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. Gold Coast, AUSTRALIA: BMJ PUBLISHING GROUP. DOI
2017	Pandos, O., Nagpal, A. N., Milton, A., Kleinig, T., Jannes, J., Koblar, S., & Hamilton-Bruce, M. A. (2017). Legislative requirements increase availability of access to certified stroke unit care. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Milton, A., Kleinig, T., Nagpal, A., Young, A. -M., Kim, S., Koblar, S. A., . . . Jannes, J. (2017). Stroke unit access update. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Balabanski, A., Goldsmith, K., Giarola, B., Buxton, D., Castle, S., McBride, K., . . . Kleinig, T. (2017). Excessive stroke incidence in Aboriginal people in Central Australia: a retrospective population-based study. Poster session presented at the meeting of Abstracts of the 27th Annual Scientific Meeting of the Stroke Society of Australasia, as published in International Journal of Stroke. Queenstown, New Zealand: SAGE Publications. DOI
2017	Kelly, J., Dowling, A., Lynch, D., Brown, A., Goldsmith, K., Hillier, S., . . . Thrift, A. (2017). Stroke rehabilitation for Aboriginal people in urban, regional and remote settings across South Australia and the Northern Territory: a qualitative study. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Balabanski, A., Newbury, J., Leyden, J., Arima, H., Anderson, C., Castle, S., . . . Kleinig, T. (2017). Excessive stroke incidence in Aboriginal people in urban and rural South Australia: Results from two population-based studies. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Bladin, C., Bagot, K., Kim, J., Vu, M., Cadigan, G., Castley, H., . . . Cadilhac, D. (2017). Working towards "no stroke untreated'': planning for the Australian Telestroke Network. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Dowie, G., Toner, P., Kleinig, T., Jannes, J., & Cheong, E. (2017). A nurse coordinated, investigation outsourced 'One Stop TIA Clinic' is feasible and economic in a resource-constrained setting. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. SAGE PUBLICATIONS LTD.
2017	Tian, H., Parsons, M., Lin, L., Aviv, R., Butcher, K., Lou, M., . . . Bivard, A. (2017). The Influence of Arterial Occlusion Location and Baseline Ischemic Core Volume on Outcome in Patients with Acute Ischemic Stroke. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2016	Goldsmith, K., Balabanski, A., Giarola, B., Buxton, D., Castle, S., McBride, K., . . . Kleinig, T. (2016). Comparison of Aboriginal and Non-Aboriginal Stroke in Central Australia: A Retrospective Cohort Study. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2016	Hamilton-Bruce, A., Kleinig, T., Royle, E., Milton, A., Koblar, S., & Jannes, J. (2016). Quantifying and Overcoming Barriers to Stroke Unit Access. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2016	Chia, N., Leyden, J., Newbury, J., Jannes, J., & Kleinig, T. (2016). Determining the Number of Ischemic Strokes Potentially Eligible for Endovascular Thrombectomy: A Population-Based Study. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2016	Goldsmith, K., Balabanski, A., Giarola, B., Buxton, D., Castle, S., McBride, K., . . . Kleinig, T. (2016). Excessive stroke incidence in Aboriginal people in Central Australia: a retrospective population-based study. Poster session presented at the meeting of Abstracts of the 10th World Stroke Congress, as published in International Journal of Stroke. Hyderabad, INDIA: SAGE Publications. DOI
2016	Asia Pacific Stroke Conference 2016. Abstracts of the Annual Conference of theAsia Pacific Stroke Organization (APSO) Combined with Stroke Society of Australasia, Brisbane, Qld., Australia, July 14-17, 2016: Abstracts (2016). Poster session presented at the meeting of Cerebrovascular Diseases. S. Karger AG. DOI
2016	Hamilton-Bruce, A., Milton, A., Miller, S., Kleinig, T., Jannes, J., & Koblar, S. (2016). Transforming Stroke Research in South Australia - A Management Program to Support Change. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2015	Campbell, B. C. V., Mitchell, P. J., Kleinig, T. J., Dewey, H. M., Churilov, L., Parsons, M. W., . . . Davis, S. M. (2015). Severe hypoperfusion in the absence of a large ischemic core should not exclude patients from reperfusion therapies. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Campbell, B. C. V., Mitchell, P. J., Kleinig, T. J., Dewey, H. M., Churilov, L., Yassi, N., . . . Davis, S. (2015). Severe hypoperfusion in the absence of a large ischemic core should not exclude patients from reperfusion therapies. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Campbell, B. C. V., Mitchell, P. J., Kleinig, T. J., Dewey, H. M., Churilov, L., Parsons, M. W., . . . Davis, S. M. (2015). CT perfusion 'target mismatch' patients have poor outcome in the absence of reperfusion. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Campbell, B. C. V., Mitchell, P. J., Kleinig, T. J., Dewey, H. M., Churilov, L., Parsons, M. W., . . . Davis, S. M. (2015). Endovascular thrombectomy reduces length of stay and treatment costs within 3 months of stroke. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL. WoS1
2015	Ben Freedman, S., Leyden, J. M., Jannes, J., Gall, S. L., Kleinig, T., Sturm, J. W., & Thrift, A. G. (2015). Stroke in people with atrial fibrillation: Is the treatment gap improving?. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Campbell, B., Mitchell, P., Kleinig, T., Dewey, H., Churilov, L., Yassi, N., . . . Davis, S. (2015). Endovascular stent-thrombectomy reduces length of stay and treatment costs within 3 months of stroke. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Campbell, B., Mitchell, P., Kleinig, T., Dewey, H., Churilov, L., Yassi, N., . . . Davis, S. (2015). Reperfusion and clinical outcome in the EXTEND-IA randomized trial. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2015	Newbury, J., Leyden, J., Castle, S., Patterson, T., Cranefield, J., Crotty, M., . . . Kleinig, T. (2015). The stroke epidemiology in a rural cohort (SEARCH) study: Lower than expected incidence but high proportions of cardioembolic stroke. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2014	Campbell, B. C. V., Mitchell, P. J., Yassi, N., Kleinig, T. J., Dewey, H., Bladin, C. F., . . . Davis, S. M. (2014). Generalizability of imaging selection for intra-arterial therapy in ischemic stroke - up to 30% of tPA patients are potentially eligible.. Poster session presented at the meeting of CEREBROVASCULAR DISEASES. KARGER.
2014	Devasagayam, S., Wyatt, B., Kleinig, T., & Leyden, J. (2014). Cerebral venous sinus thrombosis is more common than previously thought: A retrospective population-based study. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2014	Giarola, B. F., James, L. M., Kleinig, T., Newbury, J., Anderson, C. S., Jannes, J., & Lee, A. (2014). Transient ischaemic attack rarely precedes stroke in a cohort with low proportions of large artery atherosclerosis: A population-based study. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2013	Grantham, H., Larsen, R., Goldsmith, K., Leyden, J., Kleinig, T., Lee, A., & Jannes, J. (2013). Implementation of an ambulance-based stroke early notification system. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2013	Kleinig, T., Hall, L., Dowie, G., & Thompson, P. (2013). Clinical evidence for spreading cortical depression triggered by cerebral microembolism. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2013	Kleinig, T., Hall, L., Jannes, J., & Dowie, G. (2013). There's (almost) no such thing as a TIA; high rates of TIA-mimics and minor stroke in a tertiary MRI-and emergency referral-based TIA service. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL. WoS1
2013	Hall, L., & Kleinig, T. (2013). CT pulmonary angiography and duplex sonography have a high diagnostic yield in young patients with cryptogenic embolic stroke. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2012	Moey, A., Jannes, J., Koblar, S., Leyden, J., Kleinig, T., Lee, A., & Chong, K. (2012). Thrombolysis for Acute Stroke in South Australia: Have We Improved?. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.

Original Creative Works

Year	Citation
2019	Authors: Milton A, Kremer K, Rao S, Trim P, Snel M, Kleinig T, Jannes J, Koblar S. Title: FAST-IT TIA Biomarker Study. Description: N/A. Extent: Poster and Oral presentation (AGM).

Date	Project/ No.	Role	Funding Body	Amount
2015	Identifying the needs of Indigenous Australians who suffer a stroke	CID	Monash University Strategic grant Scheme	$50,000
2014	Indigenous vs Non-Indigenous stroke incidence, mortality and disease burden	CI	Heart Foundation Vanguard Grant (South Australia and Northern Territory Stroke Study (initial phase) (SAiNTSS1	$73,98
2014	Helping Stroke Physicians Choose Who to Thrombolyse – the “Targeting Optimal Thrombolysis Outcomes” (TOTO) Study. (Project Grant APP1085550)	AI	NHMRC	$1.031M
2013	Characterising post-stroke cortical plasticity in humans – identifying a critical window for rehabilitation”. (Project Grant APP1058639) .	AI	NHMRC	$735K
2009	Incidence and outcome of stroke in rural South Australia. (Project Grant: APP565042)	AI	NHMRC	$735K
2008			Pfizer Neuroscience Research Grant recipient	$37,974

Educational activities

Date	Course Title
2015-current	RACP College Examiner
2013-current	Fourth Year Medical Student Clinical Preceptor, Royal Adelaide Hospital
2013-current	Student Intern supervisor, Royal Adelaide Hospital
2011-current	Intern supervisor RAH
2011-present	Advanced trainee supervisor LMH
2010-present	Med 4/5 MSA supervisor, Lyell McEwin Hospitals
2009-present	Regular teaching sessions for nursing, allied health and junior medical staff on stroke
2009-present	Basic Physician trainee tutorials of stroke (LMH and RAH)
2007-present	LMH and RAH clinical physician trainee teaching
2004-2012	Third Year Medical Student Bed-side clinical tutor
2004-present	Occasional lectures to Medical, Dental and Health Science students on Stroke and Neurological diseases (University of Adelaide)
2004-2007	Neurology tutor for AMC candidates

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2021	Co-Supervisor	Population Based Studies of Stroke Incidence, Subtypes, Treatments and Outcomes in South Australia	Doctor of Philosophy	Doctorate	Part Time	Mr Joshua Mahadevan
2020	Co-Supervisor	PREDICTive value of aggressive risk factor modification on the occurrence of major cardiovascular events in patients with embolic STROKE	Doctor of Philosophy	Doctorate	Full Time	Dr John Leonard Fitzgerald

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2019 - 2022	Co-Supervisor	Deep Learning in the Prediction of Clinically Significant Outcomes in Stroke and General Medicine Patients	Doctor of Philosophy	Doctorate	Part Time	Mr Stephen Daniel Bacchi
2019 - 2022	Principal Supervisor	Diagnosis and Acute Management of Intracerebral Haemorrhage	Master of Philosophy (Surgery)	Master	Part Time	Mr Christopher Dillon Ovenden

Committee Memberships

Date	Role	Committee	Institution	Country
2016 - ongoing	Treasurer	Stroke Society of Australasia		Australia
2016 - ongoing	Member	Australian Stroke Triallists' Network		Australia
2016 - ongoing	Member	Australian Stroke Coalition		Australia
2015 - 2015	Co-Chair	Scientific Committee	Stroke Society of Australasia scientific meeting	Australia
2014 - 2015	Member	Adelaide Neurology/Neurosurgery Society		Australia
2013 - ongoing	Member	National Stroke Foundation Clinical Council		Australia
2013 - 2016	Treasurer	Stroke Society of Australasia		Australia
2013 - 2016	Member	Scientific Committee		Australia
2011 - ongoing	Member	State Stroke Network steering committee		Australia
2011 - ongoing	Member	Organising and Scientific Committee	Stroke society of Australasia Annual Scientific meeting	Australia
2010 - ongoing	Member	Stroke Society of Australasia		Australia
2000 - ongoing	Co-Chair	Flinders Medical Centre Resident Medical Officers' Society		Australia

Email: timothy.kleinig@adelaide.edu.au
Org Unit: Medical Specialties